大場 崇旦 (オオバ タカアキ)   

学術研究院(医学系(附属病院))

医学部附属病院 乳腺内分泌外科 

助教 

研究者情報

学位

  • 博士(医学), 信州大学

研究分野

  • 外科学一般、小児外科学, 内分泌・甲状腺・副甲状腺・乳腺外科

メールアドレス

    bes★shinshu-u.ac.jp
研究活動情報

論文

  • Fluctuations in Gut MicrobiomeComposition During Immune Checkpoint Inhibitor Therapy.
    Sarkar J, Cortes Gomez E, Oba T, Chen H, Dy GK, Segal BH, Ernstoff MS, Ito F.
    World J Oncol., 2023年
  • Predictive and Prognostic Implications of Circulating CX3CR1+ CD8+ T Cells in Non-Small Cell LungCancer Patients Treated with Chemo-Immunotherapy.
    Abdelfatah E, Long MD, Kajihara R, Oba T, Yamauchi T, Chen H, Sarkar J, Attwood K, Matsuzaki J, Segal B, DyGK, Ito F.
    Cancer Res Commun, 2023年
  • Changes in thepathophysiology of primary hyperparathyroidism and analysis of postoperative recurrence cases at a regional corehospital in Japan: experience of 35 years in Shinshu University Hospital.
    Kanai T, Oba T, Morikawa H, Amitani M, Chino T, Shimizu T, Ono MT, Maeno K, Ito KI, Ito T.
    Ann Palliat Med., 2023年
  • The Advantage of Using an Optical See-Through Head-Mounted Displayin Ultrasonography-Guided Needle Biopsy Procedures: A Prospective Randomized Study.
    Shimizu T, Oba T (co-first author), Ito KI.
    J Clin Med, 2023年
  • Neutrophil-to-lymphocyte ratio is associated with the proportion of poorly differentiated components in papillarythyroid carcinoma.
    Oba T, Kazuma M, Kiyosawa N, Morikawa H, Amitani M, Chino T Shimizu T, Ono M, Ito T, Kanai T, Ito KI.
    J Surg Res, 2023年
  • 著しい副甲状腺機能亢進を呈しながら術前画像診断が困難であった嚢胞性副甲状腺腺腫の1例
    久保田 諭史, 島田 恭輔, 髙山 昇平, 大場 崇旦, 伊藤 研一, 駒津 光久
    信州医学雑誌, 70(3), 189-194, 2022年06月電子ジャーナル
  • CD40 and CD80/86 signaling in cDC1s mediate effective neoantigen vaccination and generation of antigen-specific CX3CR1(+) CD8(+) T cells
    Yamauchi, Takayoshi; Hoki, Toshifumi; Oba, Takaaki; Kajihara, Ryutaro; Attwood, Kristopher; Cao, Xuefang; Ito, Fumito;
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 71(1), 137-151, 2022年01月WebofScience電子ジャーナル
  • がん免疫療法におけるT細胞に発現するCX3CR1の重要性
    大場 崇旦;オオバ タカアキ;伊藤 史人;イトウ フミト
    臨床免疫・アレルギー科 = Clinical immunology & allergology / 臨床免疫・アレルギー科編集委員会 編, 76(5), 573-580, 2021年11月
  • The mechanisms involved in the resistance of estrogen receptor-positive breast cancer cells to palbociclib are multiple and change over time
    Ono, Mayu; Oba, Takaaki; Shibata, Tomohiro; Ito, Ken-Ichi;
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 147(11), 3211-3224, 2021年11月WebofScience電子ジャーナル
  • In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models
    Oba, Takaaki; Makino, Kenichi; Kajihara, Ryutaro; Yokoi, Toshihiro; Araki, Ryoko; Abe, Masumi; Minderman, Hans; Chang, Alfred E.; Odunsi, Kunle; Ito, Fumito;
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 9(5), e002432, 2021年05月WebofScience電子ジャーナル
  • HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
    Oba T, Ono M, Matoba H, Uehara T, Hasegawa Y, Ito KI.
    Breast Cancer Res Treat., 186(1), 37-51, 2021年02月
  • Prognostic Nutritional Index Is Superior to Neutrophil-to-lymphocyte Ratio as a Prognostic Marker in Metastatic Breast Cancer Patients Treated With Eribulin
    Oba, Takaaki; Maeno, Kazuma; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
    ANTICANCER RESEARCH, 41(1), 445-452, 2021年01月WebofScience電子ジャーナル
  • Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer.
    9. Watanabe T, Oba T, Tanimoto K, Shibata T, Kamijo S, Ito KI.
    PLOS ONE, 2021年
  • Papillary thyroid microcarcinoma with lung metastases: a case report and review of the literature.
    11. Shimizu T, Oba T, Chino T, Soma A, Ono M, Ito T, Kanai T, Maeno K, Sato Y, Uehara T, Ito KI.
    Thyroid Res, 2021年
  • Fibroadenoma in a young male breast: A case report and review of the literature.
    13. Morikawa H, Nobuoka M, Amitani M, Shimizu T, Ohno K, Ono M, Oba T, Ito T, Kanai T, Maeno K, Uehara T, Ito KI.
    Clin Case Rep., 2021年
  • Neoadjuvant In Situ Immunomodulation Enhances Systemic Antitumor Immunity against Highly Metastatic Tumors
    Oba, Takaaki; Kajihara, Ryutaro; Yokoi, Toshihiro; Repasky, Elizabeth A.; Ito, Fumito;
    CANCER RESEARCH, 81(24), 6183-6195, 2021年WebofScience電子ジャーナル
  • Multimodal Intralesional Therapy for Reshaping the Myeloid Compartment of Tumors Resistant to Anti-PD-L1 Therapy via IRF8 Expression
    Patel, Ankit; Oba, Takaaki; Kajihara, Ryutaro; Yokoi, Toshihiro; Abrams, Scott I.; Ito, Fumito;
    JOURNAL OF IMMUNOLOGY, 207(5), 1298-1309, 2021年WebofScience電子ジャーナル
  • Local, multimodal intralesional therapy renders distant brain metastases susceptible to PD-L1 blockade in a preclinical model of triple-negative breast cancer
    Yokoi, Toshihiro; Oba, Takaaki; Kajihara, Ryutaro; Abrams, Scott, I; Ito, Fumito;
    SCIENTIFIC REPORTS, 11(1), 21992, 2021年WebofScience電子ジャーナル
  • T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors
    Yamauchi, Takayoshi; Hoki, Toshifumi; Oba, Takaaki; Jain, Vaibhav; Chen, Hongbin; Attwood, Kristopher; Battaglia, Sebastiano; George, Saby; Chatta, Gurkamal; Puzanov, Igor; Morrison, Carl; Odunsi, Kunle; Segal, Brahm H.; Dy, Grace K.; Ernstoff, Marc S.; Ito, Fumito;
    NATURE COMMUNICATIONS, 12(1), 1402, 2021年WebofScience電子ジャーナル
  • Prognostic significance of neutrophil-to-lymphocyte ratio for long-term outcomes in patients with poorly differentiated thyroid cancer
    Oba, Takaaki; Maeno, Kazuma; Amitani, Masatsugu; Shimizu, Tadafumi; Ohno, Koichi; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Uehara, Takeshi; Ito, Ken-Ichi;
    Endocrine journal, 68(11), 1329-1336, 2021年WebofScience
  • Multicenter retrospective study on the use of Curebest (TM) 95GC Breast for estrogen receptor-positive and node-negative early breast cancer
    Tsukamoto, Fumine; Arihiro, Koji; Takahashi, Mina; Ito, Ken-ichi; Ohsumi, Shozo; Takashima, Seiki; Oba, Takaaki; Yoshida, Masayuki; Kishi, Kazuki; Yamagishi, Keisuke; Kinoshita, Takayuki;
    BMC CANCER, 21(1), 1077, 2021年WebofScience電子ジャーナル