OGASAWARA Hiroshi

Academic Assembly School of Science and Technology Institute of Textile Science and Technology

Research Center for Advanced Science and Technology 

Associate Professor 

Degree

  • Doctor of Agriculture, Kinki University

Research Keyword

    Escherichia coli, Stress response, transcription, Biofilm

Educational Background

  • 2002, Kinki University, Graduate School, Division of Agriculture, Applied Biological Chemistry
  • 2005, Kinki University, Graduate School, Division of Agriculture, Applied Biological Chemistry
  • 2000, Kinki University, Faculty of Agriculture, Agricultural Chemistry

Paper

  • Roles of methionine and cysteine residues of the Escherichia coli sensor kinase HprS in reactive chlorine species sensing
    Yamaji, K., Taniguchi, R., Urano, H., Ogasawara, H.
    FEBS Lett., 597, 573-584, 2023, Refereed
  • CsgI (YccT) Is a novel Inhibitor of Curli fimbriae formation in Escherichia coli preventing CsgA polymerization and curli gene expression.
    Sano, K., Kobayashi, H., Chuta, H., Matsuyoshi, N., Kato, Y., Ogasawara, H.
    Int. J. Mol. Sci., 24, 4357, 2023, Refereed
  • Single-target regulators constitute the minority group of transcription factors in Escherichia coli K-12
    Shimada, T., Ogasawara, H., Kobayashi, I., Kobayashi, N., Ishihama, A.
    Frontiers in Microbiology, 12, 697803, 2021, Refereed
  • Cellulose acetate/multi-wall carbon nanotube/Ag nanofiber composite for antibacterial applications
    Jatoi A. W, Ogasawara H, Kim I. S. Ni Q-Q
    Materials Science & Engineering C, 110, 110679, 2020, Refereed
  • Novel regulators of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli K-12
    Ogasawara H, Ishizuka T, Hotta S, Aoki M, Shimada T, Ishihama A.
    Microbiology-SGM, 166, 880-890, 2020, Refereed
  • Fabrication of antibacterial electrospun cellulose acetate/ silver-sulfadiazine nanofibers composites for wound dressings applications
    Khan M. Q, Kharaghani D, Sanaullah, Shahzad A, Saito Y, Yamamoto T, Ogasawara H, Kim I. S
    Polymer Testing, 74, 39-44, 2019, Refereed
  • Polyvinyl alcohol nanofiber based three phase wound dressings for sustained wound healing applications
    Jatoi A. W, Ogasawara H, Kim I. S. Ni Q-Q
    Materials Letters, 241, 168-171, 2019, Refereed
  • Characterizations and application of CA/ZnO/AgNP composite nanofibers for sustained antibacterial properties
    Jatoi A. W, Kim I. S. Ogasawara H, Ni Q-Q
    Materials Science & Engineering C, 105, 110077, 2019, Refereed
  • Regulatory role of pyruvate-sensing BtsSR in biofilm formation by Escherichia coli K-12.
    Ogasawara H, Ishizuka T, Yamaji K, Kato Y, Shimada T, Ishihama A
    FEMS Microbiol Lett., 366, fnz251, 2019, Refereed
  • Dopa-based facile procedure to synthesize AgNP/cellulose nanofiber composite for antibacterial applications
    Jatoi A. W, Ogasawara H, Kim I. S. Ni Q-Q
    Applied Nanoscience, 2019, Refereed電子ジャーナル
  • Digestion of peptidoglycan near the cross-link is necessary for the growth of Bacillus subtilis
    Hashimoto, M., Matsushima, H., Suparthana, I., P., Ogasawara, H., Yamamoto, H., Teng, C., Sekiguchi, J.
    Microbiology-SGM, 164, 299-307, 2018, Refereed
  • Single-target regulators form a minor group of transcription factors in Escherichia coli K-12.
    Shimada, T., Ogasawara, H., Ishihama, A.
    Nucleic Acids Res., 46, 3921-3936, 2018, Refereed
  • Fabrication of electrospun antibacterial PVA/Cs nanofibers loaded with CuNPs and AgNPs by an in-situ method
    Kharaghani D, Khan M. Q, Tamada Y, Ogasawara H, Inoue Y, Saito, Y, Hashmi M, Kim I. S
    Polymer Testing, 72, 315-321, 2018, Refereed
  • Cross-regulation between two common ancestral response regulators, HprR and CusR, in Escherichia coli
    Urano H, Yoshida M, Ogawa A, Yamamoto K, Ishihama A, Ogasawara H
    Microbiology-SGM, 163, 243-252, 2017, Refereed
  • A structural sketch of RcdA, a transcription factor controlling the master regulator of biofilm formation
    Sugino H, Usui T, Shimada T, Nakano M, Ogasawara H, Ishihama H, Hirata A
    FEBS Lett., 591, 2019-2031, 2017, Refereed
  • Role of transcription factor NimR (YeaM) in sensitivity control of Escherichia coli to 2-nitroimidazole.
    Ogasawara H, Ohe S, Ishihama A
    FEMS Microbiol Lett., 362, 1-8, 2015, Refereed
  • Cooperative regulation of the common target genes between hydrogen peroxide-response YedVW and copper-response CusSR in Escherichia coli.
    Urano H, Umezawa Y, Yamamoto K, Ishihama A, Ogasawara H
    Microbiology-SGM, 161, 729-738, 2015, Refereed
  • Repression of flagellar genes in exponential phase by CsgD and CpxR, two crucial modulators of Escherichia coli biofilm formation.
    Dudin O, Geiselmann J, Ogasawara H, Ishihama A, Lacour S.
    J Bacteriol., 196, 707-715, 2014, Refereed
  • Involvement of cAMP-CRP in transcription activation and repression of the pck gene encoding PEP carboxykinase, the key enzyme of gluconeogenesis.
    Nakano M., Ogasawara H., Shimada T., Yamamoto K., Ishihama A.
    FEMS Microbiol. Lett, 355, 93-99, 2014, Refereed
  • Identification of the set of genes, including nonannotated morA, under the direct control of ModE in Escherichia coli.
    Kurata T, Katayama A, Hiramatsu M, Kiguchi Y, Takeuchi M, Watanabe T, Ogasawara H, Ishihama A, Yamamoto K.
    J Bacteriol, 195, 4496-4505, 2013, Refereed
  • Screening of promoter-specific transcription factors: multiple regulators for the sdiA gene involved in cell division control and quorum sensing.
    Shimada K, Ogasawara H, Yamada K, Shimura M, Kori A, Shimada T, Yamanaka Y, Yamamoto K, Ishihama A.
    Microbiology-SGM, 159, 2501-2512, 2013, Refereed
  • A novel regulation targets of the metal response BasS-BasR two-component system of Escherichia coli.
    Ogasawara H., Shinohara S, Yamamoto K, Ishihama A
    Microbiology-SGM, 158, 1482-1492, 2012, Refereed
  • A novel regulator RcdA of the csgD gene encoding the master regulator of biofilm formation in Escherichia coli.
    Shimada T, Katayama Y, Kawakita S, Ogasawara H, Nakano M, Yamamoto K, Ishihama A
    Microbiologyopen, 1, 381-394, 2012, Refereed
  • Role of the biofilm master regulator CsgD in cross-regulation between biofilm formation and flagellar synthesis
    Ogasawara, H., Yamamoto, K., Ishihama, A.
    Journal of Bacteriology, 193, 2587-2597, 2011, Refereed
  • Regulatory role of MlrA in transcription activation of csgD, the master regulator of biofilm formation in Escherichia coli.
    Ogasawara, H., Yamamoto, K., Ishihama, A.
    FEMS Microbiology Letters, 312, 160-168, 2010, Refereed
  • Regulation of the Escherichia coli csgD promoter: interplay between five transcription factors.
    Ogasawara, H., Yamada, K., Kori, A., Yamamoto, K., Ishihama, A.
    Microbiology-SGM, 156, 2470-2483, 2010, Refereed
  • The transcription regulator AllR senses both allantoin and glyoxylate and controls a set of genes for degradation and reutilization of purines.
    Hasegawa A., Ogasawara H., Kori A., Teramoto J., Ishihama A.
    Microbiology-SGM, 154, 3366 – 3378, 2008, Refereed
  • Involvement of multiple transcription factors for metal-induced spy gene expression in Escherichia coli.
    Yamamoto K., Ogasawara H., Ishihama A.
    Journal of Biotechnology, 133, 196-200, 2008, Refereed
  • PdhR (pyruvate dehydrogenase complex regulator) controls the respiratory electron transport system in Escherichia coli.
    Ogasawara H., Ishida Y., Yamada K., Yamamoto K., Ishihama A.
    Journal of Bacteriology, 189, 5534-5541, 2007, Refereed
  • Genomic SELEX Search for Target Promoters under the Control of PhoQP-RstBA Signal Relay Cascade.
    Ogasawara H., Hasegawa A., Kanda E., Miki T., Yamamoto K., Ishihama A.
    Journal of Bacteriology, 189, 4791-4799, 2007, Refereed
  • Negative regulation of DNA repair gene (uvrA) expression by ArcA/ArcB two-component system in Escherichia coli.
    Ogasawara H., Teramoto J., Yamamoto S., Hirao K., Yamamoto K., Ishihama A., Utsumi R.
    FEMS Microbiology Letters, 251, 243-249, 2005, Refereed
  • Negative regulation of DNA repair gene (ung) expression by the CpxR/CpxA two-component system in Escherichia coli K-12 and induction of mutations by increased expression of CpxR.
    Ogasawara H., Teramoto J., Hirao K., Yamamoto K., Ishihama A., Utsumi R.
    Journal of Bacteriology, 186, 8317-8325, 2004, Refereed
  • Identification and molecular characterization of the Mg2+ stimulon of Escherichia coli.
    Minagawa S., Ogasawara H., Kato A., Yamamoto K., Eguchi Y., Oshima T., Mori H., Ishihama A., Utsumi R.
    Journal of Bacteriology, 185, 3696-3702, 2003, Refereed
  • Novel mode of transcription regulation of divergently overlapping promoters by PhoP, the regulator of two-component system sensing external magnesium availavility.
    Yamamoto K., Ogasawara H., Fujita N., Utsumi R., Ishihama A.
    Molecular Microbiology, 45, 423-438, 2002, Refereed

MISC

  • 細菌アミロイドファイバーの制御と機能性材料としての利用
    大山壮哉, 松吉志, 小笠原寛
    アグリバイオ(北隆館), 7(10), 893-896, 2023, Invited
    Last, Corresponding
  • Regulation of the E. coli csgD gene encoding the master regulator of biofilm formation: Interplay between multiple transcription factors.
    Ogasawara, H., Kori, A., Yamada, K., Yamamoto, K., Ishihama, A.
    In: Proc. 2009 Internatl. Symp. Micro-Nano Mechatronics Human Sci. (Fukuda, T. et al., eds), IEEE (Institute of Electrical and Electronics Engineers), 186-189, 2009, Refereed
    Lead
  • Multi-scale genetics of transcription network: Understanding the regulatory roles of all 300 transcription factors from a single organism Escherichia coli.
    Ishihama A., Ogasawara H., Shimada T., Teramoto J., Hasegawa A., Umezawa Y., Yabuki K., Ishida Y., Inaba T., Kori A., Yamada K., Kitai Y., Kobayashi N., Kato D., and Yamamoto K.
    In Micro-Nano Mechatronics and Human Science (Fukuda, T., ed.), IEEE (Institute of Electrical and Electronics Engineers), 21-27, 2007, Refereed
  • Transcription factor promoter interaction networks.
    Ishihama A, Shimada T, Ogasawara H, Teramoto J, and Yamamoto K
    In Micro-Nano Mechatronics and Human Science (Fukuda, T., ed.), IEEE (Institute of Electrical and Electronics Engineers), 165-169, 2005, Refereed

Books and other publications

  • バイオフィルム革新的制御技術
    小笠原寛(分担), Joint work, 「大腸菌のバイオフィルム形成と遺伝子発現制御機構」
    NTS, 85-92 2023
  • Methods in Molecular Biology
    Shimada, T., Ogasawara, H., Ishihama, A., Joint work, Genomic SELEX Screening of Regulatory Targets of Escherichia coli Transcription Factors
    Springer, 49-69 2018, Refereed
  • Survival and Death in Bacteria
    Eguchi Y, Minagawa S, Ogasawara H, Yamamoto K, Utsumi R, Joint work, Signal transduction network for environmental adaptation in Escherichia coli
    Research Signport, 69-76 2005, Refereed

Lectures, oral presentations, etc.

  • Control of biofilm formation by Escherichia coli: Interplay between multiple transcription factors
    Ogasawara H, Kori A, Yamada K, Yamamoto K, and Ishihama A
    20th Internatl. Symp. Micro-NanoMechatronics Human Sci., Symp. “Systems Cell Engineering by Multi-scale Manipulation.”, 2009
  • Growth phase-dependent regulation of csgD, the master regulator of biofilm formation: Interplay between multiple transcription factors
    Ishihama, A., Ogasawara, H., Shimada, T., Teramoto, J., Kori,A., Yamada, K., Yamamoto, K
    3rd Internatl. Conf. Environmental, Industrial and Applied Microbiology (BioMicroWorld2009), 2009
  • The E.coli csgD promoter for control of biofilm formation: Interplay between eight transcription factors in promoter binding.
    Ogasawara H, Kori A.,Yamada K., Yamamoto K., Ishihama A.
    JSPS-DST Asian Academic Seminar 2008, 2008
  • Negative regulation of DNA repair gene (ung) expression by CpxR/CpxA two-component system in Escherichia coli K-12 and increased expression of CpxR.
    Ogasawara H, Teramoto J, Hirao K, Yamamoto K, Ishihama A, and Utsumi R.
    Gordon Research Conference., 2004
  • Mg2+ regulon in Escherichia coli K-12: DNA microarray-directed identification of PhoP binding site
    Ogasawara H, Minagawa S, Yamamoto K, Ishihama A, Oshima T, Mori H and Utsumi R.
    The 4th International workshop of Advanced Genomics. From Genomics to Proteomics., 2001