太田 正穂 (オオタ マサオ)
医学部 医学科 内科学第二
特任教授
研究者情報
経歴
研究活動情報
論文
- Quantitative changes of lipoprotein(a) in chronic hepatitis C patients achieving a sustained virological response by direct-acting antivirals
Okumura T, Joshita S, Sugiura A, Ota M, Umemura T
Clin Res Hepatol Gastroenterol, 46(8), 102011, 2022年08月 - The levels of IL-1beta and soluble IL-1 receptors in patients with IgG4-related periaortitis/periarteritis
Ashihara N, Ota M, Fujinaga Y, Ozawa M, Kuraishi Y, Watanabe T, Hamano H, Joshita S, Kawa S, Umemura T
Adv Med Sci, 67(2), 257-261, 2022年07月 - IL1R1 gene variants associate with disease susceptibility to IgG4-related periaortitis/periarteritis in IgG4-related disease
Umemura T, Fujinaga Y, Ashihara N, Ozawa M
GENE, 820, 146212, 2022年02月 - Association analysis of KIR/HLA genotype with liver cirrhosis, hepatocellular carcinoma, and NUC freedom in chronic hepatitis B patients
Joshita S, Ota M, Kobayashi H, Wakabayashi SI, Yamashita Y, Sugiura A, Yamazaki T, Tanaka E, Umemura T
Sci Rep, 11(1), 21424, 2021年11月 - Quantitative and qualitative lipid improvement with chronic hepatitis C virus eradication using direct-acting antivirals
Joshita S, Yamashita Y, Okamoto T, Usami Y, Sugiura A, Yamazaki T, Kakino A, Ota M, Sawamura T, Umemura T
Hepatol Res, 51(7), 758-766, 2021年07月 - Investigation of the Effect of KIR-HLA Pairs on Hepatocellular Carcinoma in Hepatitis C Virus Cirrhotic Patients
Umemura T, Joshita S, Saito H, Wakabayashi SI, Kobayashi H, Yamashita Y, Sugiura A, Yamazaki T, Ota M
Cancers (Basel), 13(13), 3267, 2021年07月
最終著者 - Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese
Suzuki H, Joshita S, Hirayama A, Shinji A, Mukawa K, Sako M, Yoshimura N, Suga T, Umemura T, Ashihara N, Yamazaki T, Ota M
Sci Rep, 10(1), 12424, 2020年07月24日
最終著者 - Virological Factors Associated With the Occurrence of Hepatitis B Virus (HBV) Reactivation in Patients With Resolved HBV Infection Analyzed Through Ultradeep Sequencing
Sakamoto K, Umemura T, Ito K, Okumura A, Joshita S, Ota M, Sugiyama M, Mizokami M, Yoneda M, Tanaka E
J Infect Dis, 221(3), 400-407, 2020年01月 - KIR/HLA genotypes confer susceptibility and progression in patients with autoimmune hepatitis
Umemura T, Joshita S, Saito H, Yoshizawa K, Norman GL, Tanaka E, Ota M
JHEP Rep, 1(5), 353-360, 2019年11月 - Quantitative analysis of serum chemokines associated with treatment failure of direct-acting antivirals in chronic hepatitis C
Umemura T, Yamazaki T, Joshita S, Sugiura A, Fujimori N, Matsumoto A, Ota M, Tanaka E
CYTOKINE, 111, 357-363, 2018年10月 - A cis-eQTL of HLA-DPB1 Affects Susceptibility to Type 1 Autoimmune Hepatitis
Yamazaki T, Umemura T, Joshita S, Yoshizawa K, Tanaka E, Ota M
Sci Rep, 8(1), 11924, 2018年08月 - Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis
Joshita S, Umemura T, Usami Y, Yamashita Y, Norman GL, Sugiura A, Yamazaki T, Fujimori N, Kimura T, Matsumoto A, Igarashi K, Yoshizawa K, Ota M, Tanaka E
Sci Rep, 8(1), 8159, 2018年05月 - KIR2DL2 combined with HLA-C1 confers risk of hepatitis C virus-related hepatocellular carcinoma in younger patients
Saito H, Umemura T, Joshita S, Yamazaki T, Fujimori N, Kimura T, Komatsu M, Matsumoto A, Tanaka E, Ota M
Oncotarget, 9(28), 19650-19661, 2018年04月 - Serum autotaxin is a useful liver fibrosis marker in patients with chronic hepatitis B virus infection
Joshita S, Ichikawa Y, Umemura T, Usami Y, Sugiura A, Shibata S, Yamazaki T, Fujimori N, Komatsu M, Matsumoto A, Igarashi K, Ota M, Tanaka E
Hepatol Res, 48(4), 275-285, 2018年03月 - Genetics and epigenetics in the pathogenesis of primary biliary cholangitis
Joshita S, Umemura T, Tanaka E, Ota M
Clin J Gastroenterol, 11(1), 11-18, 2018年02月 - Association between KIR-HLA combination and ulcerative colitis and Crohn's disease in a Japanese population
Saito H, Hirayama A, Umemura T, Joshita S, Mukawa K, Suga T, Tanaka E, Ota M
PLOS ONE, 13(4), e0195778, 2018年 - Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C
Yamazaki T, Joshita S, Umemura T, Usami Y, Sugiura A, Fujimori N, Kimura T, Matsumoto A, Igarashi K, Ota M, Tanaka E
PLOS ONE, 13(4), e0195632, 2018年 - Lack of Association of Serotonin 2A Receptor Gene in Japanese Patients with Obstructive Sleep Apnea Syndrome
Ikegawa K, Ota M, Kobayashi N, Droma Yunden, Yaegashi H, Nishizawa M, Yasuo M, Urushihata K, Yamamoto H, Hanaoka M
信州医学雑誌, 65(3), 153-162, 2017年06月10日
- Genetic polymorphism in IFNL4 and response to pegylated interferon-α and ribavirin in Japanese chronic hepatitis C patients.
Nozawa Y, Umemura T, Katsuyama Y, et al.
Tissue Antigens, 83, 45-48, 2014年 - STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
Joshita, S; Umemura, T; Nakamura, M; Katsuyama, Y; Shibata, S; Kimura, T; Morita, S; Komatsu, M; Matsumoto, A; Yoshizawa, K; Ishibashi, H; Tanaka, E; Ota, M
DISEASE MARKERS, 2014, 727393, 2014年
- Human leukocyte antigen class II haplotypes affect clinical characteristics and progression of type 1 autoimmune hepatitis in Japan.
Umemura T, Katsuyama Y, Yoshizawa K, et al.
PLOS ONE, 9(6), e100565, 2014年 - Two siblings with type 1 autoimmune pancreatitis.
Watanabe T, Maruyama M, Ito T, Kanai K, Oguchi T, Muraki T, Hamano H, Arakura N, Ota M, Kawa S
Intern Med, 52, 895-899, 2013年 - Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy.
Joshita S, Shirahata K, Yazaki Y, Okaniwa S, Nakamura Y, Kimura T, Noami S, Horigome R, Yagi H, Ito N, Yamazaki A, Akahane Y, Umemura T, Yoshizawa K, Tanaka E, Ota M
Hepatol Res, 43(7), 801-807, 2013年 - Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis.
Morita S, Joshita S, Umemura T, Katsuyama Y, Kimura T, Komatsu M, Matsumoto A, Yoshizawa K, Kamijo A, Yamamura N, Tanaka E, Ota M.
Hum Immunol, 74(2), 219-222, 2013年 - Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection.
Joshita S, Umemura T, Katsuyama Y, Ichikawa Y, Kimura T, Morita S, Kamijo A, Komatsu M, Ichijo T, Matsumoto A, Yoshizawa K, Kamijo N, Ota M, Tanaka E.
Hum Immunol., 73(3), 298-300, 2012年 - Human leukocyte antigen class II molecules confer both susceptibility and progression in japanese patients with primary biliary cirrhosis.
Umemura T, Joshita S, Ichijo T, Yoshizawa K, Katsuyama Y, Tanaka E, Ota M
Hepatology, 55(2), 506-511, 2012年 - Genetic Variants in EPAS1 Contribute to Adaptation to High-Altitude Hypoxia in Sherpas.
Hanaoka M, Droma Y, Basnyat B, Ito M, Kobayashi N, Katsuyama Y, Kubo K, Ota M
PLOS ONE, 7(12), e50566, 2012年 - Genetic background of autoimmune hepatitis in Japan.
Yoshizawa K, Umemura T, Ota M
J Gastroenterol, 46(supp 1), 42-47, 2011年 - Clinical significance of immunoglobulin G4-associated autoimmune hepatitis.
Umemura T, Zen Y, Hamano H, Joshita S, et al.
J Gastroenterol, 46(supp 1), 48-55, 2011年 - Serum Cytokine Levels are associated with the outcome of pegylated interferon and ribabirin therapy in patients with chronic hepatitis C.
Yoneda S, Umemura T, Joshita S, Ichijo T, Matsumoto A, Yoshizawa K, Katsuyama Y, Ota M, Tanaka E
Hepatol Res, 41(6), 587-593, 2011年 - Polymorphism in the KCNA3 gene is associated with susceptibility to autoimmune pancreatitis in the Japanese population.
Ota M, Ito T, Umemura T, Katsuyama Y, Yoshizawa K, Hamano H, Kawa S.
Dis Markers, 31(4), 223-229, 2011年 - Association of Serum Cytokine Levels with Treatment Response to Pegylated Interferon and Ribavirin Therapy in Genotype 1 Chronic Hepatitis C Patients.
Yoneda S, Umemura T, Katsuyama Y, Kamijo A, Joshita S, Komatsu M, Ichijo T, Matsumoto A, Yoshizawa K, Ota M, Tanaka E
J Infect Dis., 203(8), 1087-1095, 2011年 - Serum interleukin (IL)-10 and IL-12 levels and IL28B gene polymorphisms: pretreatment prediction of treatment failure in chronic hepatitis C.
Umemura T, Joshita S, Yoneda S, Katsuyama Y, Ichijo T, Matsumoto A, Yoshizawa K, Ota M, Tanaka E
Antivir Ther., 16(7), 1073-1080, 2011年 - Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci.
Mizuki N, Meguro A, Ota M, Ohno S, et al.
Nat Genet, 42(8), 703-706, 2010年 - Mitochondial DNA Diversity Among Three Subpopulations of Cynomologus Macaques (Macaca fascicularis) Originating from the Indochinese Region.
Shiina T, Tanaka K, Katsuyama Y, Otabe K, et al.
Exp Anim, 59, 567-578, 2010年 - Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients.
Joshita S, Umemura T, Yoshizawa K, Katsuyama Y, et al.
J Hepatol., 53, 537-541, 2010年 - Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.
Meguro A, Inoko H, Ota M, Mizuki N, et al.
OPHTHALMOLOGY, 117, 1331-1338, 2010年 - A2BP1 as a novel susceptible gene for primary biliary cirrhosis in Japanese patients
Joshita, Satoru; Umemura, Takeji; Yoshizawa, Kaname; Katsuyama, Yoshihiko; Tanaka, Eiji; Ota, Masao
HUMAN IMMUNOLOGY, 71(5), 520-524, 2010年 - A Novel heterophilic antibody interaction involves IgG4
Ito, T.; Kitahara, K.; Umemura, T.; Ota, M.; Shimozuru, Y.; Kawa, S.; Bahram, S.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 71(2), 109-114, 2010年 - Restriction enzyme analysis of PCR products.
Ota M, Asamura H, Oki T, Sada M
Methods Mol Biol, 578, 405-414, 2009年 - Complex divergence at a microsatellite marker C1_2_5 in the lineage of HLA-Cw/-B haplotype.
Shichi D, Ota M, Katsuyama Y, Inoko H, Naruse TK, Kimura A.
J Hum Genet, 54, 224-229, 2009年 - New susceptibility locus for high myopia is linked to the uromodulin-like 1 (UMODL1) gene region on chromosome 21q22.3.
Nishizaki R, Ota M, Inoko H, Meguro A, et al.
Eye, 23, 222-229, 2009年 - Association analysis of Toll-like receptor 4 polymorphisms with autoimmune pancreatitis
Umemura, Takeji; Katsuyama, Yoshihiko; Hamano, Hideaki; Kitahara, Kei; Takayama, Mari; Arakura, Norikazu; Kawa, Shigeyuki; Tanaka, Eiji; Ota, Masao
HUMAN IMMUNOLOGY, 70(9), 742-746, 2009年 - Microsatellite scan identifies new candidate genes for susceptibility to alcoholic chronic pancreatitis in japanese patients.
Kitahara K, Kawa S, Katsuyama Y, Umemura T, et al.
Dis Markers, 25, 175-180, 2008年 - Two hypoxia sensor genes and their association with symptoms of acute mountain sickness in Sherpas.
Droma Y, Ota M, Hanaoka M, Katsuyama Y, et al.
Aviat Space Environ Med, 79, 1056-1060, 2008年 - The Association of Transforming Growth Factor Beta 1 Gene Polymorphisms with the Emphysema Phenotype of COPD in Japanese.
Ito M, Hanaoka M, Droma Y, Hatayama O, Sato E, Katsuyama Y, Fujimoto K, Ota M.
Intern Med, 47, 1387-1394, 2008年 - Human Endogenous Retrovirus (HERVK9) Structural Polymorphism with Haplotypic HLA-A Allelic Associations.
Kulski JK, Shigenari A, Shiina T, Ota M, et al.
Genetics, 180, 445-457, 2008年 - Association of the toll-like receptor 4 gene polymorphisms with Behcet's disease.
Meguro A, Ota M, Katsuyama Y, Oka A, et al.
Ann Rheum Dis, 67, 725-727, 2008年 - Association of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with type 1 autoimmune hepatitis in Japanese.
Umemura T, Ota M, Yoshizawa K, Katsuyama Y, et al.
Hepatol Res, 38, 689-695, 2008年 - A novel immunoglobulin-immunoglobulin interaction in autoimmunity
Kawa, Shigeyuki; Kitahara, Kei; Hamano, Hideaki; Ozaki, Yayoi; Arakura, Norikazu; Yoshizawa, Kaname; Umemura, Takeji; Ota, Masao; Mizoguchi, Sadaaki; Shimozuru, Yasunori; Bahram, Seiamak
PLOS ONE, 3(2), e1637, 2008年 - Association of autoimmune pancreatitis with cyotoxic T-lymphocyte antigen 4 gene polymorphisms in Japanese patients.
Umemura T, Ota M, Hamano H, Katsuyama Y, et al.
Am J Gastroenterol, 103, 533-534, 2008年 - Adaptation with the to high altitude in sherpas: Association insertion/deletion polymorphism in the angiotensin-converting enzyme gene.
Droma Y, Hanaoka M, Basnyat B, Arjyal A, et al.
Wilderness Environ Med, 19, 22-29, 2008年 - Allele frequencies for 15STR loci in Tibetan populations from Nepal.
Ota M, Droma Y, Basnyat B, Katsuyama Y, et al.
J Forensic Sci Int., 169, 234-238, 2007年 - A genomewide DNA microsatellite association study of Japanese patients with autoimmune hepatitis type 1.
Yokosawa S, Yoshizawa K, Ota M, Katsuyama Y, et al.
Hepatology, 45, 384-390, 2007年 - Two critical genes (HLA-DRB1 and ABCF1) in the HLA region are associated with the susceptibility to autoimmune pancreatitis..
Ota M, Katsuyama Y, Hamano H, Umemura T, et al.
Immunogenetics, 59, 45-52, 2007年 - Lack of association of Toll-like receptor 9 gene polymorphism with Behcet's disease in Japanese patients
Ito, A; Ota, M; Katsuyama, Y; Inoko, H; Ohno, S; Mizuki, N
Tissue Antigens, 70(1-5), 423-426, 2007年 - Lack of association between FCRL3 and Fc gamma RII polymorphisms in Japanese type 1 autoimmune hepatitis
Umemura, T; Ota, M; Yoshizawa, K; Katsuyama, Y; Ichijo, T; Tanaka, E; Kawa, S; Kiyosawa, K
Clinical Immunology, 122(3), 338-342, 2007年 - The COL1A1 gene and high myopia susceptibility in Japanese
Inamori, Y; Ota, M; Inoko, H; Okada, E; Nishizaki, R; Shiota, T; Mok, J; Oka, A; Ohno, S; Mizuki, N
Human Genetics, 122(1-2), 151-157, 2007年 - Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism
Ota, M; Fukushima, H; Kulski, JK; Inoko, H
NATURE PROTOCOLS, 2(11), 2857-2864, 2007年 - Genetic association of Fc receptor-like 3 polymorphisms with autoimmune pancreatitis in Japanese patients
Umemura, T; Ota, M; Hamano, H; Katsuyama, Y; Kiyosawa, K; Kawa, S
Gut, 55(9), 1367-1368, 2006年 - High prevalence of hypothyroidism in patients with autoimmune pancreatitis
Komatsu, K; Hamano, H; Ochi, Y; Takayama, M; Muraki, T; Yoshizawa, K; Sakurai, A; Ota, M; Kawa, S
DIGESTIVE DISEASES AND SCIENCES, 50(6), 1052-1057, 2005年 - Genetic analysis of the HLA region of Japanese patients with type 1 autoimmune hepatitis
Yoshizawa, K; Ota, M; Katsuyama, Y; Ichijo, T; Matsumoto, A; Tanaka, E; Kiyosawa, K
JOURNAL OF HEPATOLOGY, 42(4), 578-584, 2005年
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