博士（工学）(1996), 東京大学 (主査：西郷和彦、副査：干鯛眞信、小宮山 真、相田卓三、橋本幸彦）

化学生物学

ケミカルバイオロジー, 生物有機化学

2022年
Chemistry A European Journal, Editorial board member (Wiley-VCH)

2022年
日本学術振興会学術システム研究センター研究員

2020年
科学技術振興機構創発的研究支援事業創発アドバイザー

2017年
Bioorganic Chemistry Editorial board member (Elsevier)

2016年
信州大学学術研究院（農学系）教授

2013年 - 2016年
京都大学化学研究所准教授

2005年 - 2013年
大阪大学産業科学研究所准教授

2004年 - 2005年
東京学芸大学専任講師

2003年 - 2003年
アキリオン製薬創薬部門研究員（米国コネチカット州）

1998年 - 2003年
エール大学化学科博士研究員

1991年 - 1997年
成蹊大学工学部助手

1990年 - 1991年
(株）リコー中央研究所研究員

1990年, お茶の水女子大学大学院理学研究科化学専攻

2022年 - 2022年
Nakanishi Prize選考委員会委員, 日本化学会

2022年
主査, 日本化学会生体機能関連化学・バイオテクノロジーディビジョン

2022年
プログラム委員会委員, 国際ケミカルバイオロジー学会

2021年
代議員, 日本薬学会

2020年 - 2022年
副主査, 日本化学会生体機能関連化学・バイオテクノロジーディビジョン

2019年 - 2021年
幹事, 新規素材探索研究会

2018年 - 2020年
幹事, 日本化学会生体機能関連化学・バイオテクノロジーディビジョン

2018年
代議員, 近畿化学協会

2017年 - 2019年
学術活動強化委員会委員, 日本農芸化学会

2008年
理事（レター編集担当）, 日本化学会フロンティア生命化学研究会

2008年 - 2012年
幹事, 有機合成化学協会関西支部

2017年
公益財団法人 長瀬科学技術振興財団, 長瀬研究振興賞

2016年
第21回日本女性科学者の会奨励賞

2008年
日本学術振興会平成20年度科学研究費補助金第１段審査員表彰

Functional evaluation of an electrophilic focused library to identify a covalent inhibitor against intrinsically disordered circadian clock transcription factors
Kazuya Yamanaka, Yoshihisa Inoue, Miki Imanishi, Junko Ohkanda
Bioorg. Med. Chem. Lett., in press., 2023年12月07日

Isoform-selective fluorescent labeling of 14-3-3sigma by acrylamide-containing fusicoccins
Kenta Tanaka, Yoshiya Hatano, Junko Ohkanda
Chem. Eur. J., e202301059, 2023年05月12日

Structure-activity-relationship study of semi-synthetically modified fusicoccins on their stabilization effect for 14-3-3 phoospholigand interactions
Nanami Ogino, Ryoma Masuda, LouvyLynn Punzalan, Emi Yamashita, Shota Igaue, Yoshihisa Inoue, Junko Ohkanda
Bioorg. Med. Chem., 73, 117020, 2022年09月18日

Expression and purification of DYRK1A kinase domain in complex with its folding intermediate-selective inhibitor FINDY
Ninako Kimura, Kanako Saito, Takashi Niwa, Masato Yamakawa, Shota Igaue, Junko Ohkanda, Takamitsu Hosoya, Isao Kii
Protein Expr. Purif., 196-196, 106089, 2022年03月18日

Design, synthesis, and functional evaluation of triazine-based bivalent agents that simultaneously target the active site and hot spot of phosphatase Cdc25B
Yosei Nagaoka, Prakash Parvatkar, Go Hirai, Junko Ohkanda
Bioorg. Med. Chem. Lett., 48, 128265, 2021年07月12日

Intrinsically Disordered Proteins as Regulators of Transient Biological Processes and as Untapped Drug Targets
Hosoya, Yusuke; Ohkanda, Junko;
MOLECULES, 26(8), 2021年04月

Fusicoccin: A Chemical Modulator for 14-3-3 Proteins
Ohkanda, Junko;
Chemistry Letters, 50(1), 57-67, 2021年01月

Identification of synthetic inhibitors for the DNA binding of intrinsically disordered circadian clock transcription factors
Yusuke Hosoya, Wataru Nojo, Isao Kii, Takanori Suzuki, Miki Imanishi, Junko Ohkanda
Chemical Communications, 56, 11203-11206, 2020年08月21日, 査読有り

Copper-Free Huisgen Cycloaddition for the 14-3-3-Templated Synthesis of Fusicoccin-Peptide Conjugates
Masuda, Ryoma; Kawasaki, Yuuya; Igawa, Kazunobu; Manabe, Yoshiyuki; Fujii, Hiroshi; Kato, Nobuo; Tomooka, Katsuhiko; Ohkanda, Junko;
CHEMISTRY-AN ASIAN JOURNAL, 15, 742-747, 2020年

A NOVEL CONDENSED HETEROCYCLIC QUINONE WITH A DIBENZOFURANOBISTHIADIAZOLE SKELETON
Sugawara, Kazuma; Nojo, Wataru; Ishigaki, Yusuke; Ohkanda, Junko; Suzuki, Takanori;
Heterocycles, 101(1), 99-103, 2020年

Dipicolylamine/Metal Complexes that Promote Direct Cell-Membrane Penetration of Octaarginine
Kawaguchi, Yoshimasa; Ise, Shoko; Azuma, Yusuke; Takeuchi, Toshihide; Kawano, Kenichi; Toan Khanh Le; Ohkanda, Junko; Futaki, Shiroh;
Bioconjugate chemistry, 30(2), 454-460, 2019年02月

A Guanidyl-Based Bivalent Peptidomimetic Inhibits K-Ras Prenylation and Association with c-Raf
Tsubamoto, Mai; Toan Khanh Le; Li, Minghua; Watanabe, Taku; Matsumi, Chiemi; Parvatkar, Prakash; Fujii, Hiroshi; Kato, Nobuo; Sun, Jiazhi; Ohkanda, Junko;
CHEMISTRY-A EUROPEAN JOURNAL, 25(59), 13531-13536, 2019年

Structural Effects of Fusicoccin upon Upregulation of 14-3-3-Phospholigand Interaction and Cytotoxic Activity
Ohkanda, Junko; Kusumoto, Atsushi; Punzalan, Louvy; Masuda, Ryoma; Wang, Chenyu; Parvatkar, Prakash; Akase, Dai; Aida, Misako; Uesugi, Motonari; Higuchi, Yusuke; Kato, Nobuo;
CHEMISTRY-A EUROPEAN JOURNAL, 24(60), 16066-16071, 2018年

A Strategy of Designing Mid-sized Synthetic Molecules that Recognize Interfaces of Protein protein Interactions
Ohkanda, Junko;
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 75(7), 735-745, 2017年07月

たんぱく質間相互作用を制御する合成分子の創製
大神田 淳子;
京都大学化学研究所スーパーコンピュータシステム研究成果報告書, 2016, 7-7, 2017年03月

Protein-guided self-assembly for controlling protein-protein interactions
Junko Ohkanda
Journal of the Society of Japanese Women Scientists, 17, 1-7, 2017年

タンパク質を鋳型にして薬剤を創る:低分子の標的誘導型自己組織化によるタンパク質間相互作用の調節
大神田 淳子
化学と生物, 55(11), 724-726, 2017年

Wiberg Bond Index　低原子価有機アルミニウム　Ras蛋白　有機スズ高配位化錯体
河内 敦; 吾郷 友宏; 大神田 淳子; 芝田 育也;
有機合成化学協会誌, 75(7), 772-772, 2017年

Intracellular Generation of a Diterpene-Peptide Conjugate that Inhibits 14-3-3-Mediated Interactions
Parvatkar, Prakash; Kato, Nobuo; Uesugi, Motonari; Sato, Shin-ichi; Ohkanda, Junko;*
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137(50), 15624-15627, 2015年

たんぱく質間相互作用を制御する合成分子の創製
大神田 淳子;
京都大学化学研究所スーパーコンピュータシステム研究成果報告書, 2015, 18-19, 2015年

RNA-Directed Amino Acid Coupling as a Model Reaction for Primitive Coded Translation
Harada, Kazuo*; Aoyama, Shoko; Matsugami, Akimasa; Kumar, Penmetcha K. R.; Katahira, Masato; Kato, Nobuo; Ohkanda, Junko;
ChemBioChem, 15(6), 794-798, 2014年

タンパク質間相互作用を阻害・検出する合成分子の創製
大神田 淳子;
ファルマシア, 50(11), 1101-1106, 2014年

ペプチドミメティクス化
大神田 淳子;
ファルマシア, 50(11), 1128_2-1128_2, 2014年

Module Assembly for Designing Multivalent Mid-Sized Inhibitors of Protein-Protein Interactions
Ohkanda, Junko;*
CHEMICAL RECORD, 13(6), 561-575, 2013年12月

Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers
Molzan, Manuela; Kasper, Stefan; Roeglin, Lars; Skwarczynska, Malgorzata; Sassa, Takeshi; Inoue, Takatsugu; Breitenbuecher, Frank; Ohkanda, Junko; Kato, Nobuo; Schuler, Martin; Ottmann, Christian;
ACS Chemical Biology, 8(9), 1869-1875, 2013年09月

Peptidomimetic modification improves cell permeation of bivalent farnesyltransferase inhibitors
Machida, Shinnosuke; Tsubamoto, Mai; Kato, Nobuo; Harada, Kazuo; Ohkanda, Junko;
BIOORGANIC & MEDICINAL CHEMISTRY, 21(14), 4004-4010, 2013年

A Semisynthetic Fusicoccane Stabilizes a Protein-Protein Interaction and Enhances the Expression of K+ Channels at the Cell Surface
Anders, Carolin; Higuchi, Yusuke; Koschinsky, Kristin; Bartel, Maria; Schumacher, Benjamin; Thiel, Philipp; Nitta, Hajime; Preisig-Mueller, Regina; Schlichthoerl, Guenter; Renigunta, Vijay; Ohkanda, Junko; Daut, Juergen; Kato, Nobuo; Ottmann, Christian;
CHEMISTRY & BIOLOGY, 20(4), 583-593, 2013年

Antimicrobial N-(2-chlorobenzyl)-substituted hydroxamate is an inhibitor of 1-deoxy-D-xylulose 5-phosphate synthase
Hayashi, Daisuke; Kato, Nobuo; Kuzuyama, Tomohisa; Sato, Yasuo; Ohkanda, Junko;*
Chemical Communications, 49(49), 5535-5537, 2013年

Chemical ligation of epoxide-containing fusicoccins and peptide fragments guided by 14-3-3 protein
Maki, Toshio; Kawamura, Akie; Kato, Nobuo; Ohkanda, Junko;*
MOLECULAR BIOSYSTEMS, 9(5), 940-943, 2013年

A Novel Fusicoccin Derivative Preferentially Targets Hypoxic Tumor Cells and Inhibits Tumor Growth in Xenografts
Kawakami, Koshi; Hattori, Miho; Inoue, Takatsugu; Maruyama, Yuriko; Ohkanda, Junko; Kato, Nobuo; Tongu, Miki; Yamada, Takaya; Akimoto, Miho; Takenaga, Keizo; Sassa, Takeshi; Suzumiy, Junji; Honma, Yoshio;
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 12(7), 791-800, 2012年09月

Protein recognition of hetero-/homoleptic ruthenium(II) tris(bipyridine)s for alpha-chymotrypsin and cytochrome c
Yamaguchi, Yoshinobu; Kato, Nobuo; Azuma, Hideki; Nagasaki, Takeshi; Ohkanda, Junko;*
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22(6), 2354-2358, 2012年

Phosphopeptide-Dependent Labeling of 14-3-3 zeta Proteins by Fusicoccin-Based Fluorescent Probes
Takahashi, Michiko; Kawamura, Akie; Kato, Nobuo; Nishi, Tsuyoshi; Hamachi, Itaru; Ohkanda, Junko;*
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(2), 509-512, 2012年

Bivalent Inhibitors for Disrupting Protein Surface-Substrate Interactions and for Dual Inhibition of Protein Prenyltransferases
Machida, Shinnosuke; Kato, Nobuo; Harada, Kazuo; Ohkanda, Junko;*
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(4), 958-963, 2011年

クロロキン耐性P. falciparumに対するダブルパンチ型抗マラリア剤(G 医薬化学)
大神田 淳子;
ファルマシア, 46(1), 80-81, 2010年01月01日

Design and functional evaluation of dual prenyltransferase inhibitors for simultaneous recognition of active site and exterior protein surface
Machida, Shinnosuke; Kato, Nobuo; Harada, Kazuo; Ohkanda, Junko;
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 238, 2009年

Transannular Proton Transfer in the Cyclization of Geranylgeranyl Diphosphate to Fusicoccadiene, a Biosynthetic Intermediate of Fusicoccins
Toyomasu, Tomonobu; Tsukahara, Mai; Kenmoku, Hiromichi; Anada, Masahide; Nitta, Hajime; Ohkanda, Junko; Mitsuhashi, Wataru; Sassa, Takeshi; Kato, Nobuo;
ORGANIC LETTERS, 11(14), 3044-3047, 2009年

Structurally Simple Inhibitors of Lanosterol 14 alpha-Demethylase Are Efficacious In a Rodent Model of Acute Chagas Disease
Suryadevara, Praveen Kumar; Olepu, Srinivas; Lockman, Jeffrey W.; Ohkanda, Junko; Karimi, Mandana; Verlinde, Christophe L. M. J.; Kraus, James M.; Schoepe, Jan; Van Voorhis, Wesley C.; Hamilton, Andrew D.; Buckner, Frederick S.; Gelb, Michael H.;
JOURNAL OF MEDICINAL CHEMISTRY, 52(12), 3703-3715, 2009年

Protein surface recognition by dendritic ruthenium(II) tris(bipyridine) complexes
Ohkanda, Junko; Satoh, Ritsuko; Kato, Nobuo;
Chemical Communications, (45), 6949-6951, 2009年

ビピリジン金属錯体によるセリンプロテアーゼの表面認識と阻害活性
大神田 淳子; 藤井 康平; 山口 佳史; 加藤 修雄;
ホスト・ゲスト化学シンポジウム講演要旨集, 2009, 14-14, 2009年

Module assembly for protein-surface recognition: Geranylgeranyltransferase I bivalent inhibitors for simultaneous targeting of interior and exterior protein surfaces
Machida, Shinnosuke; Usuba, Kakeru; Blaskovich, Michelle A.; Yano, Akiko; Harada, Kazuo; Sebti, Said M.; Kato, Nobuo; Ohkanda, Junko;
CHEMISTRY-A EUROPEAN JOURNAL, 14(5), 1392-1401, 2008年

Farnesyltransferase and geranylgeranyltransferase I inhibitors upregulate RhoB expression by HDAC1 dissociation, HAT association and histone acetylation of the RhoB promoter
Delarue, F. L.; Adnane, J.; Joshi, B.; Blaskovich, M. A.; Wang, D-A; Hawker, J.; Bizouarn, F.; Ohkanda, J.; Zhu, K.; Hamilton, A. D.; Chellappan, S.; Sebti, S. M.;
Oncogene, 26(5), 633-640, 2007年02月

ORGN 129-Bivalent inhibitors of Type-I geranylgeranyltransferase for simultaneous recognition of interior and exterior protein surfaces
Ohkanda, Junko; Machida, Shinnosuke; Kato, Nobuo; Blaskovich, Michelle A.; Sebti, Saied M.; Harada, Kazuo;
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 234, 2007年

Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase
Ohkanda, J; Strickland, CL; Blaskovich, MA; Carrico, D; Lockman, JW; Vogt, A; Bucher, CJ; Sun, JZ; Qian, YM; Knowles, D; Pusateri, EE; Sebti, SM; Hamilton, AD;
Organic & Biomolecular Chemistry, 4(3), 482-492, 2006年

In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability
Carrico, D; Ohkanda, J; Kendrick, H; Yokoyama, K; Blaskovich, MA; Bucher, CJ; Buckner, FS; Van Voorhis, WC; Chakrabarti, D; Croft, SL; Gelb, MH; Sebti, SM; Hamilton, AD;
BIOORGANIC & MEDICINAL CHEMISTRY, 12(24), 6517-6526, 2004年

Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents
Ohkanda, J; Buckner, FS; Lockman, JW; Yokoyama, K; Carrico, D; Eastman, R; de Luca-Fradley, K; Davies, W; Croft, SL; Van Voorhis, WC; Gelb, MH; Sebti, SM; Hamilton, AD;
JOURNAL OF MEDICINAL CHEMISTRY, 47(2), 432-445, 2004年

In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus
Bordier, BB; Ohkanda, J; Liu, P; Lee, SY; Salazar, FH; Marion, PL; Ohashi, K; Meuse, L; Kay, MA; Casey, JL; Sebti, SM; Hamilton, AD; Glenn, JS;
JOURNAL OF CLINICAL INVESTIGATION, 112(3), 407-414, 2003年08月

The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells
Bolick, SCE; Landowski, TH; Boulware, D; Oshiro, MM; Ohkanda, J; Hamilton, AD; Sebti, SM; Dalton, WS;
Leukemia, 17(2), 451-457, 2003年02月

Geranylgeranyltransferase I inhibitor GGTI-2154 induces breast carcinoma apoptosis and tumor regression in H-Ras transgenic mice
Sun, JZ; Ohkanda, J; Coppola, D; Yin, H; Kothare, M; Busciglio, B; Hamilton, AD; Sebti, SM;
CANCER RESEARCH, 63(24), 8922-8929, 2003年

A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents
Buckner, F; Yokoyama, K; Lockman, J; Aikenhead, K; Ohkanda, J; Sadilek, M; Sebti, S; Van Voorhis, W; Hamilton, A; Gelb, MH;
Proceedings of the National Academy of Sciences of the United States of America, 100(25), 15149-15153, 2003年

The farnesyltransferase inhibitor, FTI-2153, inhibits bipolar spindle formation during mitosis independently of transformation and Ras and p53 mutation status
Crespo, NC; Delarue, F; Ohkanda, J; Carrico, D; Hamilton, AD; Sebti, SM;
CELL DEATH AND DIFFERENTIATION, 9(7), 702-709, 2002年07月

CAAX peptidomimetics: Their farnesyltransferase inhibition activity and antitumor effect
Ohkanda, J;
SEIKAGAKU, 74(1), 46-50, 2002年01月

Synthesis of linear and cyclic hexapeptides with N epsilon-(1,2-dihydro-1-hydroxy-2-oxopyrimidin-4-yl)-L-lysyl-beta-alanyl as the repeating unit and properties of their iron(III) complexes
Katoh, A; Inoue, Y; Nagashima, H; Hikita, Y; Ohkanda, J; Saito, R;
Heterocycles, 58, 371-381, 2002年

Toward Chagas disease chemotherapeutics: Development of simple compounds active against Trypanosoma cruzi.
Lockman, JW; Ohkanda, J; Yokoyama, K; Eastman, RT; Buckner, FS; Gelb, MH; Hamilton, AD;
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 224, U17-U17, 2002年

Design, synthesis and evaluation of peptidomimetic farnesyltransferase inhibitor ester pro-drugs as potent antiparasitic agents.
Carrico, D; Ohkanda, J; Gelb, MH; Blaskovich, MA; Sebti, SM; Hamilton, AD;
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 224, U28-U28, 2002年

Prenyltransferase inhibitors as antitumor and antiparasitic agents: Rational design based on CAAX peptide and solution phase combinatorial approaches.
Ohkanda, J; Lockman, JW; Carrico, D; Strickland, CL; Sebti, SM; Gelb, MH; Hamilton, AD;
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 224, U30-U30, 2002年

Design and synthesis of potent nonpeptidic farnesyltransferase inhibitors based on a terphenyl scaffold
Ohkanda, J; Lockman, JW; Kothare, MA; Qian, YM; Blaskovich, MA; Sebti, SM; Hamilton, AD;
JOURNAL OF MEDICINAL CHEMISTRY, 45(1), 177-188, 2002年

3-hydroxy-4(1H)-pyridinone-containing linear and cyclic hexapeptides and their iron(III) complexes - Synthesis, property, and the growth-promotion activity-
Katoh, A; Hikita, Y; Harata, M; Ohkanda, J; Tsubomura, T; Higuchi, A; Saito, R; Harada, K;
Heterocycles, 55(11), 2171-2187, 2001年

The farnesyltransferase inhibitor, FTI-2153, blocks bipolar spindle formation and chromosome alignment and causes prometaphase accumulation during mitosis of human lung cancer cells
Crespo, NC; Ohkanda, J; Yen, TJ; Hamilton, AD; Sebti, SM;
JOURNAL OF BIOLOGICAL CHEMISTRY, 276(19), 16161-16167, 2001年

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity
Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; Hamilton, AD;
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 11(6), 761-764, 2001年

Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
Lantry, LE; Zhang, ZQ; Yao, RS; Crist, KA; Wang, Y; Ohkanda, J; Hamilton, AD; Sebti, SM; Lubet, RA; You, M;
CARCINOGENESIS, 21(1), 113-116, 2000年01月

Development of a tripeptide mimetic strategy for the inhibition of protein farnesyltransferase
Kothare, MA; Ohkanda, J; Lockman, JW; Qian, YM; Blaskovich, MA; Sebti, SM; Hamilton, AD;
Tetrahedron, 56(50), 9833-9841, 2000年

Inhibition of farnesyltransferase increases TGF beta type II receptor expression and enhances the responsiveness of human cancer cells to TGF beta
Adnane, J; Bizouarn, FA; Chen, Z; Ohkanda, J; Hamilton, AD; Munoz-Antonia, T; Sebti, SM;
Oncogene, 19(48), 5525-5533, 2000年

Synthesis of quinoxaline derivatives bearing the styryl and phenylethynyl groups and application to a fluorescence derivatization reagent
Katoh, A; Yoshida, T; Ohkanda, J;
Heterocycles, 52(2), 911-920, 2000年

Antitumor efficacy of a novel class of non-thiol-containing peptidomimetic inhibitors of farnesyltransferase and geranylgeranyltransferase I: Combination therapy with the cytotoxic agents cisplatin, taxol, and gemcitabine
Sun, JZ; Blaskovich, MA; Knowles, D; Qian, YM; Ohkanda, J; Bailey, RD; Hamilton, AD; Sebti, SM;
CANCER RESEARCH, 59(19), 4919-4926, 1999年

Novel nonthiol inhibitors of farnesyl transferase show potent antitumor properties.
Ohkanda, J; Blaskovich, M; Sun, J; Sebti, SM; Hamilton, AD;
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 218, U984-U984, 1999年

Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I
Vasudevan, A; Qian, YM; Vogt, A; Blaskovich, MA; Ohkanda, J; Sebti, SM; Hamilton, AD;
JOURNAL OF MEDICINAL CHEMISTRY, 42(8), 1333-1340, 1999年

Synthesis of 6-(bromoacetyl)amino-2,3-dimorpholinoquinoxaline and application to a new fluorescence derivatization reagent of fatty acids for the high-performance liquid chromatographic analysis
Katoh, A; Fujimoto, T; Takahashi, M; Ohkanda, J;
Heterocycles, 50(1), 299-308, 1999年

Synthesis of 2,2 '-bipyridines bearing amino or carboxyl group at the side chain and physical properties of their ruthenium(II) complexes
Katoh, A; Kitamura, Y; Fujii, H; Horie, Y; Satoh, T; Ohkanda, J; Yokomori, Y;
Heterocycles, 49, 281-296, 1998年

New hexadentate ligands composed of 1-hydroxy-2(1H)-pyrimidinone, alpha,omega-diamine and 1,1,1-tris(carboxyethoxymethyl)-ethane or tri(carboxybutyl)isocyanurate. Synthesis and characterization of their iron(III) complexes
Katoh, A; Hida, Y; Kamitani, J; Ohkanda, J;
JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, (22), 3859-3864, 1998年

Requirement for geranylgeranyl transferase I and acyl transferase in the TGF-beta-stimulated pathway leading to elastin mRNA stabilization
Kucich, U; Rosenbloom, JC; Shen, G; Abrams, WR; Blaskovich, MA; Hamilton, AD; Ohkanda, J; Sebti, SM; Rosenbloom, J;
Biochemical and biophysical research communications, 252(1), 111-116, 1998年

N-hydroxypyrazinone-bearing homotrioxacalix[3]arene: its cooperative molecular recognition by metal complexation
Ohkanda, J; Shibui, H; Katoh, A;
Chemical Communications, (3), 375-376, 1998年

N-hydroxyamide-containing heterocycles: Synthesis, reactivities, and iron(III)-chelating properties
Ohkanda, J; Katoh, A;
REVIEWS ON HETEROATOM CHEMISTRY, 18, 87-118, 1998年

Functionalized N-hydroxyamide-containing heterocycles - Synthesis, reaction, and metal-chelating property
Ohkanda, J; Katoh, A;
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 55(6), 524-534, 1997年06月

Synthesis of 1,3-linked 1,4-dihydropyridines containing the L-tyrosine residue and the influence of their structures upon the enantioselective reduction
Katoh, A; Naruse, S; Ohkanda, J; Yamamoto, H;
Heterocycles, 45(8), 1441-1446, 1997年

Novel iron sequestering agents: Synthesis and iron-chelating properties of hexadentate ligands composed of 1-hydroxy-2(1H)-pyrimidinone, omega-amino carboxylic acid, and tris(2-aminoethyl)amine
Ohkanda, J; Kamitani, J; Tokumitsu, T; Hida, Y; Konakahara, T; Katoh, A;
JOURNAL OF ORGANIC CHEMISTRY, 62(11), 3618-3624, 1997年

Structural analysis of N-(omega-phenylalkyl)substituted quinoxalin-2(1H)-ones and -thiones
Katoh, A; Yoshida, T; Ohkanda, J; Nishio, T;
Heterocycles, 44, 357-366, 1997年

N-hydroxyamide-containing heterocycles .7. Preparation and photochemical behavior of 1-benzyloxy-2(1H)-pyrazinones
Ohkanda, J; Kumasaka, T; Takasu, A; Hasegawa, T; Katoh, A;
Heterocycles, 43(4), 883-889, 1996年

Synthesis of novel amphiphilic compounds containing aza-12-crown-4 or D-glucosamine and their ion permeability
Katoh, A; Ishida, S; Ohkanda, J; Washizu, M;
Heterocycles, 43(3), 589-599, 1996年

Synthesis of 2,3-disubstituted 6-aminoquinoxalines and their application to new fluorescence derivatization reagents for carboxylic acids
Katoh, A; Takahashi, M; Ohkanda, J;
Chemistry Letters, (5), 369-370, 1996年

The influence of the chirality of synthetic iron chelators bearing N-hydroxy-2(1H)-pyrazinones and amino acid residues upon iron removal from human transferrin
Ohkanda, J; Katoh, A;
Chemistry Letters, (6), 423-424, 1996年

N-hydroxyamide-containing heterocycles .6. Application of 1-hydroxy-4,6-dimethyl-2(1H)-pyrimidinone to a new benzyloxycarbonylating agent
Katoh, A; Kondoh, S; Ohkanda, J;
HETEROCYCLIC COMMUNICATIONS, 2(2), 141-144, 1996年

N-HYDROXYAMIDE-CONTAINING HETEROCYCLES .5. SYNTHESIS OF NOVEL HEXADENTATE LIGANDS COMPOSED OF N-HYDROXY-2(1H)-PYRAZINONE, ALIPHATIC DIAMINE, AND 1,1,1-TRIS(CARBOXYETHOXYMETHYL)ETHANE, AND PROPERTIES OF THEIR FERRIC COMPLEXES
Ohkanda, J; Katoh, A;
Tetrahedron, 51(47), 12995-13002, 1995年

N-HYDROXYAMIDE-CONTAINING HETEROCYCLES .4. SYNTHESIS AND FE-III-CHELATING PROPERTIES OF NOVEL HEXADENTATE LIGANDS COMPOSED OF N-HYDROXY-2(1H)-PYRAZINONE, AMINO-ACID-RESIDUES, AND TRIS(2-AMINOETHYL)AMINE
Ohkanda, J; Katoh, A;
JOURNAL OF ORGANIC CHEMISTRY, 60(6), 1583-1589, 1995年

SYNTHESIS OF 2(1H)-PYRIMIDINONE-CONTAINING ALPHA-AMINO-ACID DERIVATIVES BY CHEMICAL MODIFICATION OF L-GLUTAMIC ACID
KATOH, A; INOKAWA, M; OHKANDA, J; MITSUHASHI, K;
CHEMICAL & PHARMACEUTICAL BULLETIN, 42(7), 1514-1517, 1994年07月

N-HYDROXYAMIDE-CONTAINING HETEROCYCLES .3. THE RING TRANSFORMATION OF 1-BENZYLOXY-2(1H)-PYRIMIDINONES INTO 2-ISOXAZOLINES WITH HYDROXYLAMINE
KATOH, A; OHKANDA, J; TAMURA, A; YOSHIIKE, Y; MITSUHASHI, K;
Heterocycles, 37(2), 1141-1146, 1994年

N-HYDROXYAMIDE-CONTAINING HETEROCYCLES .2. SYNTHESIS AND IRON(III) COMPLEX-FORMING TENDENCY OF 1-HYDROXY-2(1H)-PYRIMIDINONE AND 1-HYDROXY-2(1H)-PYRAZINONE
OHKANDA, J; TOKUMITSU, T; MITSUHASHI, K; KATOH, A;
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 66(3), 841-847, 1993年03月

A CONVENIENT SYNTHESIS OF 3-(ARYL)SUBSTITUTED 2,4(1H,3H)-PTERIDINEDIONES AND THEIR ABSORPTION AND FLUORESCENCE SPECTROSCOPIC CHARACTERISTICS
KATOH, A; OHKANDA, J; SATO, H; SAKAMOTO, T; MITSUHASHI, K;
Heterocycles, 35(2), 949-954, 1993年

N-HYDROXYAMIDE-CONTAINING HETEROCYCLES - NEW EFFECTIVE ADDITIVES FOR PEPTIDE-SYNTHESIS BY THE DICYCLOHEXYLCARBODIIMIDE METHOD
KATOH, A; OHKANDA, J; ITOH, Y; MITSUHASHI, K;
Chemistry Letters, (10), 2009-2012, 1992年10月

STRUCTURAL ASPECTS OF THE MECHANICAL AND THERMAL-DISSOCIATION OF THE CENTRAL BOND IN 2,2'-BIS(2,3,4-TRIARYLCHROMENYL)S
OHKANDA, J; MORI, Y; MAEDA, K; OSAWA, E;
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, (1), 59-63, 1992年01月

ISOLATION OF THE INTERMEDIATES AND IMPROVED SYNTHESIS OF PYRIDO[1',2'/1,2]IMIDAZOL[4,5-B]PYRAZINES AND PYRIDO[1',2'/1,2]IMIDAZOL]4,5-B]QUINOXALINES
KATOH, A; UEDA, SH; OHKANDA, J; HIROTA, M; KOMINE, H; MITSUHASHI, K;
Heterocycles, 34(10), 1965-1972, 1992年

UNUSUAL SUBSTITUENT EFFECT BY THE ALPHA-ACETYL GROUP ON THE TYPE-II PHOTOREACTION OF VALEROPHENONES - STRONG WAVELENGTH DEPENDENCE OF QUANTUM YIELDS
HASEGAWA, T; OHKANDA, J; KOBAYASHI, M; YOSHIOKA, M;
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 64(3), 299-306, 1992年

Chemical approach toward controlling of transient protein interactions, published in Middle Molecular Strategy
Junko Ohkanda, 分担執筆, Chemical approach toward controlling of transient protein interactions
Springer, Singapore, 77-96 2021年07月14日, 査読有り
ISBN:978-981-16-2457-5

Self-assembled receptors for protein surface recognition, published in Comprehensive Supramolecular Chemistry II
Junko Ohkanda, Self-Assembled Receptors for Protein Surface Recognition
Elsevier, Oxford, 351-369 2017年

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