門田 真 (カドタ シン)
学術研究院（医学系）
先鋭領域融合研究群 バイオメディカル研究所
講師
研究者情報
研究キーワード
- バイオペースメーカー, 心筋再生, 再生医療
経歴
研究活動情報
論文
- Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1.
Naoko Shiba; Xiao Yang; Mitsuto Sato; Shin Kadota; Yota Suzuki; Masahiro Agata; Kohei Nagamine; Masaki Izumi; Yusuke Honda; Tomoya Koganehira; Hideki Kobayashi; Hajime Ichimura; Shinichiro Chuma; Junichi Nakai; Shugo Tohyama; Keiichi Fukuda; Daigo Miyazaki; Akinori Nakamura; Yuji Shiba
Molecular therapy. Nucleic acids, 34, 102060-102060, 2023年12月
- Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
Yuki Tanaka; Shin Kadota; Jian Zhao; Hideki Kobayashi; Satomi Okano; Masaki Izumi; Yusuke Honda; Hajime Ichimura; Naoko Shiba; Takeshi Uemura; Yuko Wada; Shinichiro Chuma; Tsutomu Nakada; Shugo Tohyama; Keiichi Fukuda; Mitsuhiko Yamada; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba
Stem cell research & therapy, 14(1), 240-240, 2023年09月, 査読有り
筆頭著者, 責任著者 - Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy.
Silvia Marchiano; Kenta Nakamura; Hans Reinecke; Lauren Neidig; Michael Lai; Shin Kadota; Filippo Perbellini; Xiulan Yang; Jordan M Klaiman; Leslie P Blakely; Elaheh Karbassi; Paul A Fields; Aidan M Fenix; Kevin M Beussman; Anu Jayabalu; Faith A Kalucki; Akiko Futakuchi-Tsuchida; Gerhard J Weber; Sarah Dupras; Hiroshi Tsuchida; Lil Pabon; Lili Wang; Björn C Knollmann; Steven Kattman; R Scott Thies; Nathan Sniadecki; W Robb MacLellan; Alessandro Bertero; Charles E Murry
Cell stem cell, 30(4), 396-414, 2023年04月, 査読有り - Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration.
Hideki Kobayashi; Shugo Tohyama; Hideaki Kanazawa; Hajime Ichimura; Shuji Chino; Yuki Tanaka; Yota Suzuki; Jian Zhao; Naoko Shiba; Shin Kadota; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
Journal of molecular and cellular cardiology, 174, 77-87, 2022年11月, 査読有り - Chemical Genetics Reveals a Role of Squalene Synthase in TGFβ Signaling and Cardiomyogenesis.
Yasushi Takemoto; Shin Kadota; Itsunari Minami; Shinya Otsuka; Satoshi Okuda; Masahiro Abo; Louvy Lynn Punzalan; Yan Shen; Yuji Shiba; Motonari Uesugi
Angewandte Chemie (International ed. in English), 2021年08月, 査読有り - β-Arrestin–Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate
Toshihide Kashihara; Hiroyuki Kawagishi; Tsutomu Nakada; Takuro Numaga-Tomita; Shin Kadota; Elena E. Wolf; Cheng-Kun Du; Yuji Shiba; Sachio Morimoto; Mitsuhiko Yamada
JACC: Basic to Translational Science, 5(11), 1057-1069, 2020年11月, 査読有り - Heart regeneration using pluripotent stem cells.
Shin Kadota; Yuki Tanaka; Yuji Shiba
Journal of cardiology, 76(5), 459-463, 2020年11月, 招待有り
筆頭著者 - Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
Hajime Ichimura; Shin Kadota; Toshihide Kashihara; Mitsuhiko Yamada; Kuniaki Ito; Hideki Kobayashi; Yuki Tanaka; Naoko Shiba; Shinichiro Chuma; Shugo Tohyama; Tatsuichiro Seto; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
Scientific reports, 10(1), 11883-11883, 2020年07月, 査読有り, 招待無し
責任著者 - ラット心筋内におけるヒトES細胞由来心筋細胞の経時的変化
市村 創; 門田 真; 茅野 周治; 御子柴 透; 小松 正樹; 田中 晴城; 山本 高照; 大橋 伸朗; 福家 愛; 和田 有子; 柏原 俊英; 山田 充彦; 柴 祐司; 瀬戸 達一郎
日本心臓血管外科学会学術総会抄録集, 50回, O10-2, 2020年03月 - Pluripotent Stem Cell-Derived Cardiomyocyte Transplantation for Heart Disease Treatment.
Kadota S; Shiba Y
Current cardiology reports, 21(8), 73, 2019年06月, 招待有り
筆頭著者 - Long-Term Culture In Vitro Enhanced Maturation and Engraftment of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in vivo
Shin Kadota; Yuki Tanaka; Yuji Shiba
CIRCULATION, 138, 2018年11月, 査読有り, 招待無し
筆頭著者
- Cardiac Sodium Channel Disease Modeling Using Patient-Derived Induced Pluripotent Stem Cells
Shin Kadota; Naoko Shiba; Yuji Shiba
CIRCULATION JOURNAL, 81(12), 1764-1765, 2017年12月, 招待有り
筆頭著者 - Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model
Tatsuki Ogasawara; Satomi Okano; Hajime Ichimura; Shin Kadota; Yuki Tanaka; Itsunari Minami; Motonari Uesugi; Yuko Wada; Naoto Saito; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
SCIENTIFIC REPORTS, 7(1), 8630, 2017年08月, 査読有り, 招待無し - In Vivo Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Neonatal and Adult Rat Hearts.
Kadota S; Pabon L; Reinecke H; Murry CE
Stem cell reports, 8(2), 278-289, 2017年02月, 査読有り, 招待無し
筆頭著者 - Ribonucleotide reductase-mediated increase in dATP improves cardiac performance via myosin activation in a large animal model of heart failure
Shin Kadota; John Carey; Hans Reinecke; James Leggett; Sam Teichman; Michael A. Laflamme; Charles E. Murry; Michael Regnier; Gregory G. Mahairas
EUROPEAN JOURNAL OF HEART FAILURE, 17(8), 772-781, 2015年08月, 査読有り, 招待無し
筆頭著者 - Development of a reentrant arrhythmia model in human pluripotent stem cell-derived cardiac cell sheets
Shin Kadota; Itsunari Minami; Nobuhiro Morone; John E. Heuser; Konstantin Agladze; Norio Nakatsuji
European Heart Journal, 34(15), 1147-1156, 2013年04月, 査読有り, 招待無し
筆頭著者 - A Small Molecule that Promotes Cardiac Differentiation of Human Pluripotent Stem Cells under Defined, Cytokine- and Xeno-free Conditions
Itsunari Minami; Kohei Yamada; Tomomi G. Otsuji; Takuya Yamamoto; Yan Shen; Shinya Otsuka; Shin Kadota; Nobuhiro Morone; Maneesha Barve; Yasuyuki Asai; Tatyana Tenkova-Heuser; John E. Heuser; Motonari Uesugi; Kazuhiro Aiba; Norio Nakatsuji
CELL REPORTS, 2(5), 1448-1460, 2012年11月, 査読有り, 招待無し - Curvature-dependent excitation propagation in cultured cardiac tissue
S. Kadota; M. W. Kay; N. Magome; K. Agladze
JETP Letters, 94(11), 824-830, 2012年02月, 査読有り, 招待無し
筆頭著者 - [Embryonic stem cell research].
Kadota S; Aiba K; Nakatsuji N
Nihon rinsho. Japanese journal of clinical medicine, 69(12), 2109-2113, 2011年12月, 招待無し
筆頭著者 - The association between post-load low insulin level and high mortality rates in patients with no previous diagnosis of diabetes mellitus
Shin Kadota; Mitsuo Matsuda; Masayasu Izuhara; Osamu Baba; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito
INTERNATIONAL JOURNAL OF CARDIOLOGY, 148(1), 59-63, 2011年04月, 査読有り, 招待無し - A case of marked ST depression and myocardial injury as a result of disulfiram-ethanol reaction
Keisuke Shioji; Masayasu Izuhara; Shin Kadota; Osamu Baba; Hirokazu Mitsuoka; Takashi Uegaito; Mitsuo Matsuda
Journal of Cardiology Cases, 1(3), e137-e140, 2010年06月, 査読有り, 招待無し - A case of right atrial angiosarcoma: The utility of PET and CT fusion imaging in detecting a malignant cardiac tumor
Shin Kadota; Mitsuo Matsuda; Nao Umei; Masayasu Izuhara; Osamu Baba; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito; Takuma Satsu; Masahiko Onoe; Eiji Kadota
Journal of Cardiology Cases, 1(2), e84-e87, 2010年04月, 査読有り, 招待無し - Determinant factors of plasma B-type natriuretic peptide levels in patients with persistent nonvalvular atrial fibrillation and preserved left ventricular systolic function
Osamu Baba; Masayasu Izuhara; Shin Kadota; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito; Satoru Mutsuo; Mitsuo Matsuda
JOURNAL OF CARDIOLOGY, 54(3), 402-408, 2009年12月, 査読有り, 招待無し - Relationship of Cardio-Ankle Vascular Index (CAVI) to Carotid and Coronary Arteriosclerosis
Masayasu Izuhara; Keisuke Shioji; Shin Kadota; Osamu Baba; Yuzo Takeuchi; Takashi Uegaito; Satoru Mutsuo; Mitsuo Matsuda
CIRCULATION JOURNAL, 72(11), 1762-1767, 2008年11月, 査読有り, 招待無し - The importance of serial cardiac troponin measurement for evaluating the response to immunosuppressive therapy for myocarditis
Shin Kadota; Yuzo Takeuchi; Masayasu Izuhara; Osamu Baba; Keisuke Shioji; Takashi Uegaito; Eiji Kadota; Mitsuo Matsuda
JOURNAL OF CARDIOLOGY, 52(2), 154-158, 2008年10月, 査読有り, 招待無し - Long-term effects of early statin therapy for patients with acute myocardial infarction treated with stent implantation
Shin Kadota; Mitsuo Matsuda; Masayasu Izuhara; Osamu Baba; Soji Moriwaki; Keisuke Shioji; Yuzo Takeuchi; Takashi Uegaito
JOURNAL OF CARDIOLOGY, 51(3), 171-178, 2008年06月, 査読有り, 招待無し - Cardiac tamponade due to a ruptured solitary mediastinal varix: A case report
Toshio Kaneda; Masahiko Onoe; Soji Moriwaki; Shin Kadota; Osamu Baba; Mitsuo Matsuda; Eiji Kadota; Toshihiko Saga
HEART SURGERY FORUM, 10(3), E199-E201, 2007年06月, 査読有り, 招待無し - Intestinal decontamination using povidone-iodine compromises small bowel storage quality
DW Olson; S Kadota; A Cornish; KL Madsen; J Zeng; LD Jewell; DL Bigam; TA Churchill
TRANSPLANTATION, 75(9), 1460-1462, 2003年05月, 査読有り, 招待無し - Ribonucleotide reductase-mediated increase in dATP improves cardiac performance via myosin activation in a large animal model of heart failure
Shin Kadota; John Carey; Hans Reinecke; James Leggett; Sam Teichman; Michael A. Laflamme; Charles E. Murry; Michael Regnier; Gregory G. Mahairas
筆頭著者 - Development of a reentrant arrhythmia model in human pluripotent stem cell-derived cardiac cell sheets
Shin Kadota; Itsunari Minami; Nobuhiro Morone; John E. Heuser; Konstantin Agladze; Norio Nakatsuji
筆頭著者 - The association between post-load low insulin level and high mortality rates in patients with no previous diagnosis of diabetes mellitus
Shin Kadota; Mitsuo Matsuda; Masayasu Izuhara; Osamu Baba; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito - A case of right atrial angiosarcoma: The utility of PET and CT fusion imaging in detecting a malignant cardiac tumor
Shin Kadota; Mitsuo Matsuda; Nao Umei; Masayasu Izuhara; Osamu Baba; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito; Takuma Satsu; Masahiko Onoe; Eiji Kadota - Determinant factors of plasma B-type natriuretic peptide levels in patients with persistent nonvalvular atrial fibrillation and preserved left ventricular systolic function
Osamu Baba; Masayasu Izuhara; Shin Kadota; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito; Satoru Mutsuo; Mitsuo Matsuda - Long-term effects of early statin therapy for patients with acute myocardial infarction treated with stent implantation
Shin Kadota; Mitsuo Matsuda; Masayasu Izuhara; Osamu Baba; Soji Moriwaki; Keisuke Shioji; Yuzo Takeuchi; Takashi Uegaito - Intestinal decontamination using povidone-iodine compromises small bowel storage quality
DW Olson; S Kadota; A Cornish; KL Madsen; J Zeng; LD Jewell; DL Bigam; TA Churchill
MISC
- 【不整脈治療の最新デバイステクノロジーとリードマネジメント】ペースメーカ バイオペースメーカ
門田 真; 柴 祐司
循環器ジャーナル, 68(3), 422-427, 2020年07月 - ヒト多能性幹細胞由来心筋細胞を用いたバイオペースメーカーの開発
門田 真
福田記念医療技術振興財団情報, (31), 89-92, 2018年12月 - iPS細胞を用いた新しい心不全治療法開発
門田 真; 柴 祐司
心臓, 49(12), 1203-1207, 2017年 - 多能性幹細胞を用いた心筋再生治療
門田 真; 柴 祐司
信州医学雑誌 = The Shinshu medical journal, 65(3), 143-152, 2017年 - BB-R12, a Novel Gene Therapy for Heart Failure
Sam L. Teichman; Shin Kadota; Michael Regnier; Charles E. Murry; Michael Laflamme; Gregory G. Mahairas
CIRCULATION, 130, 2014年11月 - PE-087 The Influence of Hyperglycemia on Admission and Post-load Insulin Response for Patients with Acute Coronary Syndrome without Treated Diabetes Mellitus(PE015,ACS/AMI (Clinical/Pathophysiology) 1 (IHD),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
Kadota Shin; Matsuda Mitsuo; Izuhara Masayasu; Baba Osamu; Mitsuoka Hirokazu; Shioji Keisuke; Uegaito Takashi
Circulation journal : official journal of the Japanese Circulation Society, 73, 420-420, 2009年03月01日 - PE-253 Assessment of the Relation between Plasma B-type Natriuretic Peptide (BNP) Concentrations and Serum Amino-terminal proBNP (Nt-proBNP) Concentrations(PE043,Heart Failure (Biomarker) 1 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
Baba Osamu; Matsuda Mitsuo; Uegaito Takashi; Shioji Keisuke; Mitsuoka Hirokazu; Kadota Shin; Izuhara Masayasu
Circulation journal : official journal of the Japanese Circulation Society, 73, 462-463, 2009年03月01日 - PJ-168 Post-load Reduced Insulin Level is Associated with High Mortality Rates in Patients with No Previous Diagnosis of Diabetes Mellitus(PJ029,Diabetes 2 (H),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
Kadota Shin; Matsuda Mitsuo; Izuhara Masayasu; Baba Osamu; Mitsuoka Hirokazu; Shioji Keisuke; Uegaito Takashi
Circulation journal : official journal of the Japanese Circulation Society, 73, 588-588, 2009年03月01日 - Postload Reduced Insulin Level Is Associated With High Mortality Rates in Patients With no Previous Diagnosis of Diabetes Mellitus
Shin Kadota; Mitsuo Matsuda; Masayasu Izuhara; Osamu Baba; Hirokazu Mitsuoka; Keisuke Shioji; Takashi Uegaito
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 53(10), A347-A347, 2009年03月 - PJ-426 The Cardio-Ankle Vascular Index (CAVI), the Novel Aortic Stiffness Parameter, is Related with the Carotid Artery Sclerosis(Cerebrovascular circulation/Stroke(02)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
Shioji Keisuke; Izuhara Masayasu; Kadota Shin; Baba Osamu; Takeuchi Yuzo; Uegaito Takashi; Mutsuo Satoru; Matsuda Mitsuo
Circulation journal : official journal of the Japanese Circulation Society, 72, 619-619, 2008年03月01日 - PJ-845 Post-load hyperinsulinemia is a significant determinant factor in association with multivessel coronary artery disease in patients with impaired glucose tolerance(Diabetes / Obesity / Metabolic syndrome(16)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
Matsuda Mitsuo; Izuhara Masayasu; Kadota Shin; Baba Osamu; Shioji Keisuke; Takeuchi Yuzo; Uegaito Takashi; Mutsuo Satoru
Circulation journal : official journal of the Japanese Circulation Society, 72, 724-724, 2008年03月01日 - OE-258 Long-term Effect of Statin Therapy for Patients with Acute Myocardial Infarction Treated with Stent Implantation(Acute myocardial infarction, clinical (diagnosis/treatment)-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
Kadota Shin; Izuhara Masayasu; Baba Osamu; Moriwaki Soji; Shioji Keisuke; Takeuchi Yuzo; Uegaito Takashi; Matsuda Mitsuo
Circulation journal : official journal of the Japanese Circulation Society, 71, 215-215, 2007年03月01日 - Ischemic duodenitis
H. Seno; S. Mikami; K. Komatsu; S. Kadota; S. Yazumi; T. Chiba
Endoscopy, 37(1), 91, 2005年01月
