医学博士, 京都大学

循環器内科学, 循環内科学、分子循環器病学、心血管内分泌代謝内科学

2016年
信州大学医学部循環器内科学教室（内科学第五教室）　教授　

2013年 - 2013年
京都大学大学院医学研究科循環器内科学　講師

2013年 - 2013年
京都大学大学院医学研究科糖尿病・内分泌・栄養内科学　講師

2009年 - 2013年
京都大学大学院医学研究科内分泌代謝内科学　講師

2009年 - 2009年
京都大学大学院医学研究科内分泌代謝内科学　特定講師

2005年 - 2009年
京都大学大学院医学研究科内分泌代謝内科学　産学連携講師

2003年 - 2005年
テキサス大学サウスウエスタン医学研究所分子生物学講座 フェロー

2000年 - 2003年
日本学術振興会特別研究員

1995年 - 2000年, 京都大学, 大学院医学研究科

1985年 - 1991年, 京都大学, 医学部

2015年
第3回日本心不全学会学術賞

2015年
第18回日本臨床分子医学会学会賞

2013年
第38回（2012年度）日本心臓財団　佐藤賞

2010年
日本内分泌学会研究奨励賞

2009年
日本心血管内分泌代謝学会高峰譲吉研究奨励賞

2005年
American Heart Association New Investigator Travel Award

2004年
日本循環器学会 第14回八木賞

2001年
日本心血管内分泌代謝学会若手研究者奨励賞

2001年
American Heart Association Melvin L. Marcus Young Investigator Award

2001年
日本内分泌学会若手研究者奨励賞

2001年
日本心脈管作動物質学会研究奨励賞

2000年
日本循環器学会若手研究者奨励賞

1999年
日本心不全学会若手研究者奨励賞

1999年
日本臨床分子医学会研究奨励賞

神経体液性因子抑制の新しい展開 : ARNIおよび新世代MRA
桑原 宏一郎
Heart View, 26(1), 68-74, 2022年01月

Current use of inotropes according to initial blood pressure and peripheral perfusion in the treatment of congestive heart failure: findings from a multicentre observational study
Nagao, Kazuya; Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Su, Kanae; Kawato, Mitsunori; Seko, Yuta; Inada, Tsukasa; Inoko, Moriaki; Toyofuku, Mamoru; Furukawa, Yutaka; Nakagawa, Yoshihisa; Ando, Kenji; Kadota, Kazushige; Shizuta, Satoshi; Ono, Koh; Sato, Yukihito; Kuwahara, Koichiro; Ozasa, Neiko; Kimura, Takeshi;
BMJ OPEN, 12(1), e053254, 2022年01月

Gigantic Pacemaker Pocket Abscess Infected by Staphylococcus epidermidis
Okano T, Okada A, Shoda M, Kuwahara K
Intern Med, 61(4), 593-594, 2022年

Effects of cardiac surgical support on long‑term outcomes of emergent or complex percutaneous coronary intervention cases: a sub‑analysis of the SHINANO 5‑year registry
Nakamura C, Ebisawa S, Miura T, Nomi H, Kanzaki Y, Yui H, Maruyama S, Nagae A, Ueki Y, Sakai T, Kato T, Saigusa T, Okada A, Motoki H, Kuwahara K
Heart Vessels, 37(7), 1106-1114, 2022年

Comparison of prognostic impact of anticoagulants in heart failure patients with atrial fibrillation and renal dysfunction: direct oral anticoagulants versus vitamin K antagonists
Sakai T, Motoki H, Fuchida A, Takeuchi T, Otagiri K, Kanai M, Kimura K, Minamisawa M, Yoshie K, Saigusa T, Ebisawa S, Okada A, Kitabayashi H, Kuwahara K
Heart Vessels, 37(7), 1232-1241, 2022年

Successful endovascular treatment with a stent graft for chronic deep vein thrombosis with multiple arteriovenous fstulas: a case report
Kato T, Fuke M, Nagai F, Nomi H, Kanzaki Y, Yui H, Maruyama S, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K
J Med Case Rep, 16(1), 257, 2022年

Cilostazol effectiveness in reducing drugcoated stent restenosis in the superficial femoral artery: The ZERO study
Miura T, Miyashita Y, Hozawa K, Doijiri T, Kato T, Hayakawa N, Hashizume N, Nakano M, Ikeda U, Kuwahara K, on behalf of the ZERO Investigators
PLOS ONE, 17(7), e0270992, 2022年

Usefulness of the controlled-rotation dilator sheath “Evolution RL” for extraction of old leads in two Japanese centers – An experience in use
Tabata H, Okada A, Kobayashi H, Shoin W, Okano T, Higuchi S, Yagishita D, Ebisawa S, Motoki H, Shoda M, Kuwahara K
J Cardiol, 80(4), 339-343, 2022年

Gender diference in heart failure with preserved ejection fraction:clinical profles, examinations, and prognosis
Sakai T, Motoki H, Suzuki S, Fuchida A, Takeuchi T, Otagiri K, Kanai M, Kimura K, Minamisawa M, Yoshie K, Saigusa T, Ebisawa S, Okada A, Kitabayashi H, Kuwahara K
Heart Vessels, 37(10), 1710-1718, 2022年

The Impact of Hyperuricemia on Patients With Low Body Mass Index After Endovascular Treatments: Data From the I-PAD Registry
Nagae A, Ebisawa S, Saigusa T, Nishikawa K, Fujimori K, Yui H, Maruyama S, Nakamura C, Kashiwagi D, Kobayashi H, Sakai T, Senda K, Kato T, Miura T, Okada A, Motoki H, Kuwahara K
Angiology, 73(8), 753-763, 2022年

Intensive exercise therapy for restenosis after superficial femoral artery stenting: the REASON randomized clinical trial
Kato T, Miura T, Yamamoto S, Miyashita Y, Hashizume N, Shoin K, Sasaki S, Kanzaki Y, Yui H, Maruyama S, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Ikeda U, Kuwahara K; REASON Investigators
Heart Vessels, 37(9), 1596-1603, 2022年

Impact of Frailty and Age on Clinical Outcomes in Patients Who Underwent Endovascular Therapy
Nishikawa K, Ebisawa S, Miura T, Kato T, Kanzaki Y, Abe N, Yokota D, Yanagisawa T, Senda K, Wakabayashi T, Oyama Y, Karube K, Itagaki T, Yui H, Maruyama S, Nagae A, Sakai T, Okina Y, Nakazawa S, Tsukada S, Saigusa T, Okada A, Motoki H, Kagoshima M, Kuwahara K
J Endovasc Ther, 29(6), 845-854, 2022年

Infective endocarditis caused by Streptococcus pneumoniae from sinusitis: A case report
Yamazaki K, Miura T, Sunohara D, Komatsu T, Mochidome T, Kasai T, Ikeda U, Kuwahara K
J Cardiol Cases, 25(5), 279-281, 2022年

NRSF-GNAO1 Pathway Contributes to the Regulation of Cardiac Ca2+ Homeostasis
Inazumi H, Kuwahara K, Nakagawa Y, Kuwabara Y, Numaga-Tomita T, Kashihara T, Nakada T, Kurebayashi N, Oya M, Nonaka M, Sugihara M, Kinoshita H, Moriuchi K, Yanagisawa H, Nishikimi T, Motoki H, Yamada M, Morimoto S, Otsu K, Mortensen RM, Nakao K, Kimura T
Circ Res, 130(2), 234-248, 2022年

Coronary angiography in patients with acute heart failure: from the KCHF registry
Seko Y, Kishimori T, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators
ESC Heart Fail, 9(1), 531-544, 2022年

Insomnia in patients with acute heart failure: from the KCHF registry
Seko Y, Yamamoto E, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators
ESC Heart Fail, 9(5), 2988-2996, 2022年

Changes in BNP levels from discharge to 6-month visit predict subsequent outcomes in patients with acute heart failure
Shiba M, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Nakagawa Y, Kuwahara K, Kimura T
PLOS ONE, 17(1), e0263165, 2022年

Left atrial reverse remodeling improves risk stratification in patients with heart failure with recovered ejection fraction
Shiba M, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Seko Y, Yamamoto E, Yoshikawa Y, Kitai T, Yamashita Y, Iguchi M, Nagao K, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T
Sci Rep, 12(1), 4473, 2022年

Current use of inotropes according to initial blood pressure and peripheral perfusion in the treatment of congestive heart failure: findings from a multicentre observational study
Nagao K, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inada T, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Ozasa N, Kimura T
BMJ OPEN, 12(1), e053254, 2022年

Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through β-adrenoceptors
Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, Kato Y, Numaga-Tomita T, Kaneko T, Mangmool S, Kuroda T, Okubo R, Sanbo M, Hirabayashi M, Sato Y, Nakagawa Y, Kuwahara K, Nagata R, Iribe G, Mori Y, Nishida M
Nat Commun, 13(1), 6374, 2022年

NRSF/REST-Mediated Epigenomic Regulation in the Heart: Transcriptional Control of Natriuretic Peptides and Beyond
Inazumi H, Kuwahara K
Biology, 11(8), 1197, 2022年

Appetite loss at discharge from acute decompensated heart failure: Observation from KCHF registry
Yamamoto E, Kato T, Yaku H, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Kawato M, Seko Y, Shiba M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kimura T
PLOS ONE, 17(5), e0267327, 2022年

Public assistance in patients with acute heart failure: a report from the KCHF registry
Nishimoto Y, Kato T, Morimoto T, Taniguchi R, Yaku H, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Seko Y, Inoko M, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Kuwahara K, Ozasa N, Sato Y, Kimura T
ESC Heart Fail, 9(3), 1920-1930, 2022年

Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial
Shimizu Y, Kondo K, Hayashida R, Sasaki KI, Ohtsuka M, Fukumoto Y, Takashima S, Inoue O, Usui S, Takamura M, Sakuma M, Inoue T, Nagata T, Akashi YJ, Yamada Y, Kato T, Kuwahara K, Tateno K, Kobayashi Y, Shibata R, Murohara T; TACT-ADRC multicenter trial Group
Angiogenesis, 25(4), 535-546, 2022年

Starting Neurohormonal Antagonists in Patients With Acute Heart Failure With Mid-Range and Preserved Ejection Fraction
Seko Y, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators
Circ J, 86(10), 1547-1558, 2022年

Prevention of Contrast-Induced Nephropathy After Cardiovascular Catheterization and Intervention With High-Dose Strong Statin Therapy in Japan - The PREVENT CINC-J Study
Watanabe M, Aonuma K, Murohara T, Okumura Y, Morimoto T, Okada S, Nakamura S, Uemura S, Kuwahara K, Takayama T, Doi N, Nakajima T, Horii M, Ishigami K, Nomoto K, Abe D, Oiwa K, Tanaka K, Koyama T, Sato A, Ueda T, Soeda T, Saito Y; PREVENT CINC-J Investigators
Circ J, 86(9), 1455-1463, 2022年

Status of adult outpatients with congenital heart disease in Japan: The Japanese Network of Cardiovascular Departments for Adult Congenital Heart Disease Registry
Yao A, Inuzuka R, Mizuno A, Iwano H, Tatebe S, Tsukamoto Y, Sakamoto I, Watanabe H, Fukuda N, Takechi F, Adachi S, Akazawa Y, Kuwahara K, Dohi K, Ishizu T, Miyake M, Koitabashi N, Hasegawa-Tamba S, Sato S, Fujii T, Ehara E, Minamino T, Yamada H, Yamashita E, Kawamatsu N, Masuda K, Soma K, Shiraishi I, Nagai R, Niwa K; JNCVD-ACHD investigators
J Cardiol, 80(6), 525-531, 2022年

Body composition and mortality in patients undergoing endovascular treatment for peripheral artery disease
Itagaki, Tadashi; Ebisawa, Soichiro; Otagiri, Kyuhachi; Kato, Tamon; Miura, Takashi; Kanzaki, Yusuke; Abe, Naoyuki; Yokota, Daisuke; Yanagisawa, Takashi; Senda, Keisuke; Okina, Yoshiteru; Wakabayashi, Tadamasa; Oyama, Yushi; Karube, Kenichi; Machida, Keisuke; Takeuchi, Takahiro; Saigusa, Tatsuya; Motoki, Hirohiko; Kitabayashi, Hiroshi; Kuwahara, Koichiro;
Heart and Vessels, 36(12), 1830-1840, 2021年12月

Relationship between the flood disaster caused by the Reiwa first year east Japan typhoon and cardiovascular and cerebrovascular events in Nagano City: The SAVE trial
Sunohara, Daisuke; Miura, Takashi; Komatsu, Toshinori; Hashizume, Naoto; Momose, Tomoyasu; Kono, Tsunesuke; Motoki, Hirohiko; Mochidome, Tomoaki; Kasai, Toshio; Kuwahara, Koichiro; Ikeda, Uichi;
Journal of cardiology, 78(5), 447-455, 2021年11月

The natriuretic peptide system in heart failure: Diagnostic and therapeutic implications
Kuwahara, Koichiro;
PHARMACOLOGY & THERAPEUTICS, 227, 107863, 2021年11月

Prognostic ability of mid-term worsening renal function after percutaneous coronary intervention: findings from the SHINANO registry
Okina, Yoshiteru; Miura, Takashi; Senda, Keisuke; Taki, Minami; Kobayashi, Masanori; Kanai, Masafumi; Okuma, Yukari; Yanagisawa, Takashi; Hashizume, Naoto; Otagiri, Kyuhachi; Shoin, Kyoko; Watanabe, Noboru; Ebisawa, Soichiro; Karube, Kenichi; Nakajima, Hiroyuki; Saigusa, Tatsuya; Miyashita, Yusuke; Kashiwagi, Daisuke; Machida, Keisuke; Abe, Naoyuki; Tachibana, Takahiro; Kanzaki, Yusuke; Maruyama, Takuya; Nomi, Hidetomo; Sakai, Takahiro; Yui, Hisanori; Mochidome, Tomoaki; Kobayashi, Takahiro; Kasai, Toshio; Ikeda, Uichi; Kuwahara, Koichiro;
Heart and Vessels, 36(10), 1496-1505, 2021年10月

Percutaneous Removal of a Displaced Inferior Vena Cava Filter Using a Loop-Wire Technique and Lead-Extraction Sheaths
Fujimori, Koki; Okada, Ayako; Tabata, Hiroaki; Shoda, Morio; Kuwahara, Koichiro;
CIRCULATION JOURNAL, 85(8), 1403-1403, 2021年08月

Association between Inter-atrial Septum Motion and Persistent Atrial Fibrillation Recurrence after Catheter Ablation
Kobayashi Hideki, Okada Ayako, Tabata Hiroaki, Shoin Wataru, Okano Takahiro, Yoshie Koji, Oguchi Yasutaka, Kato Ken, Motoki Hirohiko, Shoda Morio, Kuwahara Koichiro
信州医学雑誌, 69(4), 189-201, 2021年08月

Prognostic significance of diastolic blood pressure in patients with heart failure with preserved ejection fraction
Fuchida, Aya; Suzuki, Sho; Motoki, Hirohiko; Kanzaki, Yusuke; Maruyama, Takuya; Hashizume, Naoto; Kozuka, Ayako; Yahikozawa, Kumiko; Kuwahara, Koichiro;
Heart and Vessels, 36(8), 1159-1165, 2021年08月

A decrease in tricuspid regurgitation pressure gradient associates with favorable outcome in patients with heart failure
Seko, Yuta; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Shiba, Masayuki; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Yamashita, Yugo; Iguchi, Moritake; Nagao, Kazuya; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi; KCHF Study Investigators;
ESC HEART FAILURE, 8(4), 2826-2836, 2021年08月

Multisystem Inflammatory Syndrome in Children - A New Syndrome Complicated With Acute Heart Failure Following Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection -
Uchida, Momoko; Kashima, Yuichiro; Mochizuki, Katsunori; Sakamoto, Hiroto; Mori, Kotaro; Ebisawa, Soichiro; Takeshige, Kanako; Nitta, Kenichi; Kuwahara, Koichiro; Imamura, Hiroshi;
CIRCULATION JOURNAL, 85(6), 948-952, 2021年06月

Safe and effective transvenous lead extraction for elderly patients utilizing non-laser and laser tools: a single-center experience in Japan
Okada, Ayako; Tabata, Hiroaki; Shoda, Morio; Shoin, Wataru; Kobayashi, Hideki; Okano, Takahiro; Yoshie, Koji; Kato, Ken; Saigusa, Tatsuya; Ebisawa, Soichiro; Motoki, Hirohiko; Kuwahara, Koichiro;
Heart and Vessels, 36(6), 882-889, 2021年06月

第三世代ミネラルコルチコイド受容体拮抗薬(MRA) (特集 新規心不全治療薬の使い方)
桑原 宏一郎;クワハラ コウイチロウ
医学のあゆみ, 277(4), 281-284, 2021年04月24日

心筋胎児型遺伝子発現調節経路 (特集 ナトリウム利尿ペプチドに関する話題)
桑原 宏一郎;クワハラ コウイチロウ
循環器内科 = Cardioangiology / 循環器内科編集委員会 編, 89(4), 375-378, 2021年04月

Serum cholinesterase as a prognostic biomarker for acute heart failure
Shiba, Masayuki; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Seko, Yuta; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Yamashita, Yugo; Iguchi, Moritake; Nagao, Kazuya; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
EUROPEAN HEART JOURNAL-ACUTE CARDIOVASCULAR CARE, 10(3), 335-342, 2021年03月

Searching for the Frequency of Cardiac Transthyretin Amyloidosis among Elderly Heart Failure Patients Noninvasively Using 99mTc-labeled Pyrophosphate Scintigraphy
Miura, Takashi; Okina, Yoshiteru ; Mochidome, Tomoaki; Kobayashi, Takahiro; Kasai, Toshio; Ikeda, Uichi; Ezawa, Naoki; Sekijima, Yoshiki; Kuwahara, Koichiro
信州医学雑誌, 69(1), 37-44, 2021年02月10日

KCHF Study InvestigatorsSex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry (vol 7, pg 2485, 2020)
Yamamoto, Erika; Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Yoshikawa, Yusuke; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Himura, Yoshihiro; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawato, Mitsunori; Seko, Yuta; Toyofuku, Mamoru; Furukawa, Yutaka; Nakagawa, Yoshihisa; Ando, Kenji; Kadota, Kazushige; Shizuta, Satoshi; Ono, Koh; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi; KCHF Study Investigators;
ESC HEART FAILURE, 8(1), 784-784, 2021年02月

Prognostic usefulness of residual SYNTAX score combined with clinical factors for patients with acute coronary syndrome who underwent percutaneous coronary intervention from the SHINANO Registry
Kashiwagi, Daisuke; Ebisawa, Soichiro; Yui, Hisanori; Maruyama, Shusaku; Nagae, Ayumu; Sakai, Takahiro; Kato, Tamon; Saigusa, Tatsuya; Okada, Ayako; Motoki, Hirohiko; Kuwahara, Koichiro;
Heart and Vessels, 36(2), 170-179, 2021年02月

Visualization of Spatially-Controlled Vasospasm by Sympathetic Nerve-Mediated ROCK Activation
Imanishi, Ayako; Ichise, Hiroshi; Fan, Chuyun; Nakagawa, Yasuaki; Kuwahara, Koichiro; Sumiyama, Kenta; Matsuda, Michiyuki; Terai, Kenta;
AMERICAN JOURNAL OF PATHOLOGY, 191(1), 194-203, 2021年01月

"Alpha"-Looped Broken Pacemaker Lead Inside the Heart
Tabata, Hiroaki; Okada, Ayako; Kobayashi, Hideki; Shoin, Wataru; Okano, Takahiro; Yoshie, Koji; Motoki, Hirohiko; Shoda, Morio; Kuwahara, Koichiro;
CIRCULATION JOURNAL, 85(1), 77-77, 2021年01月

Impact of nutritional index on long-term outcomes of elderly patients with coronary artery disease: sub-analysis of the SHINANO 5 year registry
Maruyama, Shusaku; Ebisawa, Souichiro; Miura, Takashi; Yui, Hisanori; Kashiwagi, Daisuke; Nagae, Ayumu; Sakai, Takahiro; Kato, Tamon; Saigusa, Tatsuya; Okada, Ayako; Motoki, Hirohiko; Kuwahara, Koichiro;
Heart and Vessels, 36(1), 7-13, 2021年01月

Influence of Worsening Heart Failure During Hospitalization on the Prognosis in Patients with Acute Decompensated Heart Failure
Yamamoto, Erika; Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
Circulation, 144, 2021年

Inflammation-based assessment for the risk stratification of mortality in patients with heart failure
Itagaki, Tadashi; Motoki, Hirohiko; Otagiri, Kyuhachi; Machida, Keisuke; Takeuchi, Takahiro; Kanai, Masafumi; Kimura, Kazuhiro; Higuchi, Satoko; Minamisawa, Masatoshi; Kitabayashi, Hiroshi; Kuwahara, Koichiro;
SCIENTIFIC REPORTS, 11(1), 14989, 2021年

Leadless cardiac pacemaker implantations after infected pacemaker system removals in octogenarians
Higuchi, Satoshi; Okada, Ayako; Shoda, Morio; Yagishita, Daigo; Saito, Satoshi; Kanai, Miwa; Kataoka, Shohei; Yazaki, Kyoichiro; Tabata, Hiroaki; Kobayashi, Hideki; Shoin, Wataru; Okano, Takahiro; Yoshie, Koji; Ejima, Koichiro; Kuwahara, Koichiro; Hagiwara, Nobuhisa;
JOURNAL OF GERIATRIC CARDIOLOGY, 18(7), 505-513, 2021年

Admission systolic blood pressure as a prognostic predictor of acute decompensated heart failure: A report from the KCHF registry
Kawase, Yuichi; Kato, Takao; Morimoto, Takeshi; Hata, Reo; Murai, Ryosuke; Tada, Takeshi; Katoh, Harumi; Kadota, Kazushige; Yamamoto, Erika; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Yoshikawa, Yusuke; Iguchi, Moritake; Nagao, Kazuya; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
PLOS ONE, 16(7), e0253999, 2021年

Predictive Value of Abdominal Fat Distribution on Coronary Artery Disease Severity Stratified by Computed Tomography-Derived SYNTAX Score
Otagiri, Kyuhachi; Machida, Keisuke; Itagaki, Tadashi; Takeuchi, Takahiro; Tsujinaka, Yusuke; Yui, Hisanori; Nakamura, Chie; Sakai, Takahiro; Kato, Tamon; Saigusa, Tatsuya; Ebisawa, Soichiro; Motoki, Hirohiko; Kuwahara, Koichiro; Kitabayashi, Hiroshi;
AMERICAN JOURNAL OF CARDIOLOGY, 150, 32-39, 2021年

Absolute quantitative analysis of cardiac amyloidosis using SPECT/CT with Tc-99m-pyrophosphate
Yanagisawa, Shin; Takahashi, Yusuke; Sasaki, Jun; Takasone, Ken; Yoshie, Koji; Koyama, Jun; Katoh, Nagaaki; Yazaki, Masahide; Kuwahara, Koichiro; Fujinaga, Yasunari; Sekijima, Yoshiki;
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 28(3), 213-214, 2021年

Protocol: Prospective observational study investigating the prevalence and clinical outcome of portopulmonary hypertension in Japanese patients with chronic liver disease
Wakabayashi, Shun-ichi; Joshita, Satoru; Kimura, Kazuhiro; Motoki, Hirohiko; Kobayashi, Hiroyuki; Yamashita, Yuki; Sugiura, Ayumi; Yamazaki, Tomoo; Kuwahara, Koichiro; Umemura, Takeji;
PLOS ONE, 16(4), 2021年

Lower In-Hospital Mortality With Beta-Blocker Use at Admission in Patients With Acute Decompensated Heart Failure
Tamaki, Yodo; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Ozasa, Neiko; Yamamoto, Erika; Yoshikawa, Yusuke; Miyake, Makoto; Kondo, Hirokazu; Tamura, Toshihiro; Kitai, Takeshi; Iguchi, Moritake; Nagao, Kazuya; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawato, Mitsunori; Toyofuku, Mamoru; Sato, Yukihito; Kuwahara, Koichiro; Nakagawa, Yoshihisa; Kato, Takao; Kimura, Takeshi; KCHF Study Investigators;
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(13), 2021年

A case of transient ventricular pre-excitation associated with takotsubo cardiomyopathy
Kobayashi, Hideki; Tabata, Hiroaki; Shoin, Wataru; Okano, Takahiro; Yoshie, Koji; Okada, Ayako; Shoda, Morio; Kuwahara, Koichiro;
JOURNAL OF ELECTROCARDIOLOGY, 65, 73-75, 2021年

Association of the Prognosis of Ankle-brachial Index Improvement One Year Following Endovascular Therapy in Patients with Peripheral Artery Disease: Data from the I-PAD NAGANO Registry
Senda, Keisuke; Miura, Takashi; Kato, Tamon; Kanzaki, Yusuke; Abe, Naoyuki; Yokota, Daisuke; Yanagisawa, Takashi; Okina, Yoshiteru; Wakabayashi, Tadamasa; Oyama, Yushi; Karube, Kenichi; Itagaki, Tadashi; Yoda, Hidetsugu; Shoin, Kyoko; Oguchi, Yasutaka; Aizawa, Katsuyuki; Suzuki, Chihiro; Kuwahara, Koichiro; I-PAD NAGANO Registry Investigator;
INTERNAL MEDICINE, 60(13), 1999-2006, 2021年

Prognostic value of reduction in left atrial size during a follow-up of heart failure: an observational study
Shiba, Masayuki; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Seko, Yuta; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Yamashita, Yugo; Iguchi, Moritake; Nagao, Kazuya; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi; KCHF Study Investigators;
BMJ OPEN, 11(2), e044409, 2021年

Impact of Frailty and Age on Clinical Outcomes in Patients Who Underwent Endovascular Therapy
Nishikawa, Ken; Ebisawa, Soichiro; Miura, Takashi; Kato, Tamon; Yusuke, Kanzaki; Abe, Naoyuki; Yokota, Daisuke; Yanagisawa, Takashi; Senda, Keisuke; Wakabayashi, Tadamasa; Oyama, Yushi; Karube, Kenichi; Itagaki, Tadashi; Yui, Hisanori; Maruyama, Shusaku; Nagae, Ayumu; Sakai, Takahiro; Okina, Yoshiteru; Nakazawa, Shun; Tsukada, Shunichi; Saigusa, Tatsuya; Okada, Ayako; Motoki, Hirohiko; Kagoshima, Mitsuru; Kuwahara, Koichiro;
JOURNAL OF ENDOVASCULAR THERAPY, 29(6), 15266028211067728, 2021年

Ischemic Stroke in Acute Decompensated Heart Failure: From the KCHF Registry
Iguchi, Moritake; Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Hamatani, Yasuhiro; Yamashita, Yugo; Masunaga, Nobutoyo; Ogawa, Hisashi; Ishii, Mitsuru; An, Yoshimori; Taniguchi, Ryoji; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawato, Mitsunori; Seko, Yuta; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Abe, Mitsuru; Akao, Masaharu; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(21), e022525, 2021年

Improved and new-onset anemia during follow-up in patients with acute decompensated heart failure Characteristics and outcomes
Seko, Yuta; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Shiba, Masayuki; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Yamashita, Yugo; Iguchi, Moritake; Nagao, Kazuya; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi; KCHF Study Investigators;
MEDICINE, 100(32), e26892, 2021年

Newly Diagnosed Infection After Admission for Acute Heart Failure: From the KCHF Registry
Seko, Yuta; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Shiba, Masayuki; Yamamoto, Erika; Yoshikawa, Yusuke; Yamashita, Yugo; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Nagao, Kazuya; Jinnai, Toshikazu; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi; KCHF Study Investigators;
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(22), e023256, 2021年

Risk Factors and Clinical Outcomes of Nonhome Discharge in Patients With Acute Decompensated Heart Failure: An Observational Study
Washida, Koichi; Kato, Takao; Ozasa, Neiko; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Seko, Yuta; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Yamashita, Yugo; Iguchi, Moritake; Nagao, Kazuya; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(15), e020292, 2021年

心不全薬物治療の最前線
桑原 宏一郎
信州医学雑誌, 68(6), 349-355, 2020年12月

Impact of changes in body mass index after percutaneous coronary intervention on long-term outcomes in patients with coronary artery disease
Yui, Hisanori; Ebisawa, Soichiro; Miura, Takashi; Nakamura, Chie; Maruyama, Shusaku; Kashiwagi, Daisuke; Nagae, Ayumu; Sakai, Takahiro; Kato, Tamon; Saigusa, Tatsuya; Okada, Ayako; Motoki, Hirohiko; Kuwahara, Koichiro;
Heart and Vessels, 35(12), 1657-1663, 2020年12月

Prognostic impact of mineralocorticoid receptor antagonist in patients with heart failure with preserved ejection fraction
Suzuki, Sho; Motoki, Hirohiko; Kanzaki, Yusuke; Maruyama, Takuya; Hashizume, Naoto; Kozuka, Ayako; Yahikozawa, Kumiko; Kuwahara, Koichiro;
ESC HEART FAILURE, 7(5), 2752-2761, 2020年10月

Rationale and design of the EMPYREAN study
Motoki, Hirohiko; Masuda, Izuru; Yasuno, Shinji; Oba, Koji; Shoin, Wataru; Usami, Satoru; Saito, Yoshihiko; Waki, Masako; Komatsu, Mitsuhisa; Ueshima, Kenji; Nakagawa, Yasuaki; Son, Cheol; Yonemitsu, Shin; Hiramitsu, Shinya; Konda, Manako; Onishi, Katsuya; Kuwahara, Koichiro;
ESC HEART FAILURE, 7(5), 3134-3141, 2020年10月

Sex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry
Yamamoto, Erika; Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Himura, Yoshihiro; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawato, Mitsunori; Seko, Yuta; Toyofuku, Mamoru; Furukawa, Yutaka; Nakagawa, Yoshihisa; Ando, Kenji; Kadota, Kazushige; Shizuta, Satoshi; Ono, Koh; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi; KCHF Study Investigators;
ESC HEART FAILURE, 7(5), 2485-2493, 2020年10月

Sodium-Glucose Cotransporter-2 inhibitors are potential therapeutic agents for treatment of non-diabetic heart failure patients
Nakagawa, Yasuaki; Kuwahara, Koichiro;
Journal of cardiology, 76(2), 123-131, 2020年08月

Prognostic significance of resting heart rate in atrial fibrillation patients with heart failure with reduced ejection fraction
Suzuki, Sho; Motoki, Hirohiko; Kanzaki, Yusuke; Maruyama, Takuya; Hashizume, Naoto; Kozuka, Ayako; Yahikozawa, Kumiko; Kuwahara, Koichiro;
Heart and Vessels, 35(8), 1109-1115, 2020年08月

Impact of Ambulation Status in Patients with End-stage Renal Disease on Hemodialysis due to Diabetic Nephropathy : The PREDICT Study
Kato T, Miyashita Y, Sone H, Mizukami T, Kanno Y, Oguchi T, Yokota D, Shiotsuki N, Mizukami E, Terashima M, Aruga M, Yui H, Maruyama S, Kobayashi H, Kashiwagi D, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K
信州医学雑誌, 68(3), 131-138, 2020年06月10日

Prognostic Impact of Cardio-renal-anemia Syndrome in Patients at Risk for Heart Failure from the IMPACT-ABI study
Shoin W, Ebisawa S, Saigusa T, Sakai T, Oguchi Y, Okada A, Motoki H, Kuwahara K
信州医学雑誌, 68(3), 139-147, 2020年06月10日

A Predictive Model for 6-Month Mortality in Elderly Patients with Heart Failure
Suzuki, Sho; Motoki, Hirohiko; Kanzaki, Yusuke; Maruyama, Takuya; Hashizume, Naoto; Kozuka, Ayako; Yahikozawa, Kumiko; Kuwahara, Koichiro;
INTERNATIONAL HEART JOURNAL, 61(2), 325-331, 2020年03月

Risk factors and clinical outcomes of functional decline during hospitalisation in very old patients with acute decompensated heart failure: an observational study
Yaku, Hidenori; Kato, Takao; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Kato, Masashi; Ikeda, Tomoyuki; Furukawa, Yutaka; Nakagawa, Yoshihisa; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
BMJ OPEN, 10(2), 2020年02月

A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis
Endo, Jin; Sano, Motoaki; Izumiya, Yasuhiro; Tsujita, Kenichi; Nakamura, Kazufumi; Tahara, Nobuhiro; Kuwahara, Koichiro; Inomata, Takayuki; Ueda, Mitsuharu; Sekijima, Yoshiki; Ando, Yukio; Tsutsui, Hiroyuki; Isobe, Mitsuaki; Fukuda, Keiichi;
CIRCULATION JOURNAL, 84(1), 15-17, 2020年01月

Association of an increase in serum albumin levels with positive 1-year outcomes in acute decompensated heart failure: A cohort study
Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawato, Mitsunori; Seko, Yuta; Shiba, Masayuki; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
PLOS ONE, 15(12), 2020年

Cardio-renal and cardio-hepatic interactions predict cardiovascular events in elderly patients with heart failure
Okano, Takahiro; Motoki, Hirohiko; Minamisawa, Masatoshi; Kimura, Kazuhiro; Kanai, Masafumi; Yoshie, Koji; Higuchi, Satoko; Saigusa, Tatsuya; Ebisawa, Soichiro; Okada, Ayako; Shoda, Morio; Kuwahara, Koichiro;
PLOS ONE, 15(10), 2020年

Association between body mass index and prognosis of patients hospitalized with heart failure
Seko, Yuta; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Ozasa, Neiko; Shiba, Masayuki; Yamamoto, Erika; Yoshikawa, Yusuke; Yamashita, Yugo; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Toyofuku, Mamoru; Furukawa, Yutaka; Ando, Kenji; Kadota, Kazushige; Sato, Yukihito; Kuwahara, Koichiro; Kimura, Takeshi;
SCIENTIFIC REPORTS, 10(1), 2020年

Impact of left ventricular ejection fraction on the effect of renin-angiotensin system blockers after an episode of acute heart failure: From the KCHF Registry
Yoshikawa, Yusuke; Tamaki, Yodo; Morimoto, Takeshi; Yaku, Hidenori; Yamamoto, Erika; Inuzuka, Yasutaka; Ozasa, Neiko; Kitai, Takeshi; Nagao, Kazuya; Sato, Yukihito; Kondo, Hirokazu; Tamura, Toshihiro; Nakagawa, Yoshihisa; Kuwahara, Koichiro; Kato, Takao; Kimura, Takeshi;
PLOS ONE, 15(9), 2020年

Increased Ga(o)Expression Regulated by NRSF Plays a Key Role in the Development of Heart Failure Through the Impairment of Ca2+ Homeostasis
Inazumi, Hideaki; Nakagawa, Yasuaki; Moriuchi, Kenji; Kuwahara, Koichiro;
Circulation Research, 127, 2020年

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo
Ichimura, Hajime; Kadota, Shin; Kashihara, Toshihide; Yamada, Mitsuhiko; Ito, Kuniaki; Kobayashi, Hideki; Tanaka, Yuki; Shiba, Naoko; Chuma, Shinichiro; Tohyama, Shugo; Seto, Tatsuichiro; Okada, Kenji; Kuwahara, Koichiro; Shiba, Yuji;
SCIENTIFIC REPORTS, 10(1), 2020年

MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice
Ito, Sohei; Hashimoto, Yohei; Majima, Ryohei; Nakao, Eichi; Aoki, Hiroki; Nishihara, Michihide; Ohno-Urabe, Satoko; Furusho, Aya; Hirakata, Saki; Nishida, Norifumi; Hayashi, Makiko; Kuwahara, Koichiro; Fukumoto, Yoshihiro;
PLOS ONE, 15(3), 2020年

Association with Controlling Nutritional Status (CONUT) Score and In-hospital Mortality and Infection in Acute Heart Failure
Kato, Takao; Yaku, Hidenori; Morimoto, Takeshi; Inuzuka, Yasutaka; Tamaki, Yodo; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Su, Kanae; Kawato, Mitsunori; Seko, Yuta; Inoko, Moriaki; Toyofuku, Mamoru; Furukawa, Yutaka; Nakagawa, Yoshihisa; Ando, Kenji; Kadota, Kazushige; Shizuta, Satoshi; Ono, Koh; Sato, Yukihito; Kuwahara, Koichiro; Ozasa, Neiko; Kimura, Takeshi;
SCIENTIFIC REPORTS, 10(1), 2020年

C-reactive protein at discharge and 1-year mortality in hospitalised patients with acute decompensated heart failure: an observational study
Nishimoto, Yuji; Kato, Takao; Morimoto, Takeshi; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Yamamoto, Erika; Yoshikawa, Yusuke; Kitai, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Su, Kanae; Kawato, Mitsunori; Seko, Yuta; Inoko, Moriaki; Toyofuku, Mamoru; Furukawa, Yutaka; Nakagawa, Yoshihisa; Ando, Kenji; Kadota, Kazushige; Shizuta, Satoshi; Ono, Koh; Kuwahara, Koichiro; Ozasa, Neiko; Sato, Yukihito; Kimura, Takeshi;
BMJ OPEN, 10(12), 2020年

Prognostic significance of high-sensitivity cardiac troponin in patients with heart failure with preserved ejection fraction
Suzuki, Sho; Motoki, Hirohiko; Minamisawa, Masatoshi; Okuma, Yukari; Shoin, Wataru; Okano, Takahiro; Kimura, Kazuhiro; Ebisawa, Soichiro; Okada, Ayako; Kuwahara, Koichiro;
Heart and Vessels, 34(10), 1650-1656, 2019年10月

Ankle-Brachial Index as a Prognostic Indicator in Patients with Atrial Fibrillation -A Subanalysis of the IMPACT-ABI Study
Oguchi Y, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K
信州医学雑誌, 67(3), 197-204, 2019年06月10日

Establishment of a Healthcare System for Patients with Adult Congenital Heart Disease in Collaboration with Children’s Hospitals: The Nagano Model
Motoki H, Yasukochi S, Takigiku K, Takei K, Okamura T, Kimura K, Minamisawa M, Okada A, Saigusa T, Ebisawa S, Seto T, Shoda M, Okada K, Kuwahara K
Circ J, 83(2), 424-431, 2019年

Epicardial Stone: Unfamiliar Calcified Mass at the Site of a Left Ventricular Old Myocardial Infarction
Tabata H, Motoki H, Sakai T, Okada A, Kuwahara K
Circ J, 83(9), 262, 2019年

Atrial and brain natriuretic peptides: Hormones secreted from the heart
Nakagawa Y, Nishikimi T, Kuwahara K
PEPTIDES, 111, 18-25, 2019年

A case of thrombolytic therapy with recombinant tissue plasminogen activator for mechanical valve thrombosis at 9 weeks of pregnancy in a Japanese woman
Komatsu T, Motoki H, Kimura K, Saigusa T, Ebisawa S, Yokokawa Y, Ando H, Ichino T, Kuwahara K.
J Cardiol Cases, 19(1), 15-18, 2019年

Wire perforation causing cardiopulmonary arrest during radiofrequency hot balloon ablation for pulmonary vein isolation
Okano T, Okada A, Tabata H, Kobayashi H, Shoin W, Yoshie K, Oguchi Y, Shoda M, Kuwahara K
J Cardiol Cases, 19(5), 169-172, 2019年

Association between reactive hyperemia peripheral arterial tonometry index and atrial fibrillation recurrence after catheter ablation
Kobayashi H, Okada A, Tabata H, Shoin W, Okano T, Yoshie K, Oguchi Y, Kato K, Shoda M, Kuwahara K
Int J Cardiol Heart Vasc, 24, 100385, 2019年

Prognostic significance of high‑sensitivity cardiac troponin in patients with heart failure with preserved ejection fraction
Suzuki S, Motoki H, Minamisawa M, Okuma Y, Shoin W, Okano T, Kimura K, Ebisawa S, Okada A, Kuwahara K
Heart Vessels, 34(10), 1650-1656, 2019年

Impact of inpatient cardiac rehabilitation on Barthel Index score and prognosis in patients with acute decompensated heart failure
Motoki H, Nishimura M, Kanai M, Kimura K, Minamisawa M, Yamamoto S, Saigusa T, Ebisawa S, Okada A, Kuwahara K
Int J Cardiol, 293, 125-130, 2019年

MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages
An J, Naruse TK, Hinohara K, Soejima Y, Sawabe M, Nakagawa Y, Kuwahara K, Kimura A
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 133, 26-35, 2019年

Comparison of leg loader and treadmill exercise for evaluating patients with peripheral artery disease
Ueki Y, Miura T, Mochidome T, Senda K, Ebisawa S, Saigusa T, Motoki H, Okada A, Koyama J, Kuwahara K
Heart Vessels, 34(4), 590-596, 2019年

Role of echocardiography in assessing cardiac amyloidosis : a systematic review
Koyama J, Minamisawa M, Sekijima Y, Kuwahara K, Katsuyama T, Maruyama K
J Echocardiogr, 17(2), 64-75, 2019年

Successful inferior vena cava filter removal using pacemaker lead extraction methods
Itagaki T, Okada A, Tabata H, Shoin W, Kobayashi H, Okano T, Oguchi Y, Mochidome T, Saigusa T, Ebisawa S, Motoki H, Shoda M, Kuwahara K
J Cardiol Cases, 19(4), 129-132, 2019年

Biopsy detection and clinical management of acute lymphocytic myocarditis in pregnancy
Sunohara D, Motoki H, Saigusa T, Ebisawa S, Okada A, Ando H, Sato M, Kuwahara K
J Cardiol Cases, 20(5), 164-167, 2019年

Comparison of Long-Acting and Short Acting Loop Diuretics in the Treatment of Heart Failure With Preserved Ejection Fraction
Suzuki S, Motoki H, Kanzaki Y, Maruyama T, Hashizume N, Kozuka A, Yahikozawa K, Kuwahara K
Circ Rep, 1, 137-141, 2019年

Impact of Therapeutic Angiogenesis Using Autologous Bone Marrow-Derived Mononuclear Cells Implantation in Critical Limb Ischemia With Scleroderma - Subanalysis of the Long-Term Clinical Outcomes Survey
Shoji K, Yanishi K, Yoshimi R, Hamada N, Kondo K, Fujimoto K, Nakajima H, Kuwahara K, Higashi Y, Fukumoto Y, Murohara T, Matoba S; TACT Follow up Study Investigators
Circ J, 83(3), 662-671, 2019年

Utility of copeptin for predicting long-term clinical outcomes inpatients with heart failure
Yoshikawa Y, Shiomi H, Kuwahara K, Sowa N, Yaku H, Yamashita Y, Tazaki J, Imai M, Kato T, Saito N, Shizuta S, Ono K, Kimura T
J Cardiol, 73(5), 379-385, 2019年

Association of Mineralocorticoid Receptor Antagonist Use With All-Cause Mortality and Hospital Readmission in Older Adults With Acute Decompensated Heart Failure
Yaku H, Kato T, Morimoto T, Inuzuka Y, Tamaki Y, Ozasa N, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Seko Y, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators
JAMA Netw Open, 2(6), e195892, 2019年

Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia
Oshita K, Kozasa Y, Nakagawa Y, Kuwabara Y, Kuwahara K, Nakagawa T, Nakashima N, Hiraki T, Takano M
J Physiol Sci, 69(4), 653-660, 2019年

Impact of inpatient cardiac rehabilitation on Barthel Index score and prognosis in patients with acute decompensated heart failure
Motoki, Hirohiko; Nishimura, Musashi; Kanai, Masafumi; Kimura, Kazuhiro; Minamisawa, Masatoshi; Yamamoto, Shuhei; Saigusa, Tatsuya; Ebisawa, Soichiro; Okada, Ayako; Kuwahara, Koichiro;
International Journal of Cardiology, 293, 125-130, 2019年

⼼筋梗塞後のマウス心臓におけるミトコンドリアーアクチン相互作⽤の病態生理学的意義
田中 智弘;安田 智;佐藤 陽治;桑原 宏一郎;熊谷 嘉人;赤池 孝章;井手 友美;王子田 彰夫;森 泰生;西田 基宏;西村 明幸;下田 翔;島内 司;外山 隆;北島 直幸;石川 達也;進藤 直哉;沼賀-富田 拓郎
日本薬理学会年会要旨集, 92, 2-YIA-21, 2019年

利尿薬の新しい展開
桑原 宏一郎
心臓, 51(4), 383-387, 2019年

心房細動アブレーション：肺静脈隔離術 (Pulmonary vein isolation : PVI)
岡田 綾子;田畑 裕章;酒井 貴弘;三枝 達也;海老澤 聡一朗;元木 博彦;小山 潤;庄田 守男;桑原 宏一郎
信州医学雑誌, 67(4), 259-262, 2019年

Predictive Value of Underweight Status for Patients with Peripheral Artery Disease with Claudication
Senda, Keisuke; Miura, Takashi; Minamisawa, Masatoshi; Ueki, Yasushi; Mochidome, Tomoaki; Nomi, Hidetomo; Shoin, Wataru; Higuchi, Satoko; Oguchi, Yasutaka; Nishimura, Hitoshi; Saigusa, Tatsuya; Ebisawa, Soichiro; Motoki, Hirohiko; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;
Angiology, 69(6), 513-522, 2018年07月

Geriatric Nutritional Risk Index Predicts Cardiovascular Events in Patients at Risk for Heart Failure
Minamisawa, Masatoshi; Miura, Takashi; Motoki, Hirohiko; Ueki, Yasushi; Nishimura, Hitoshi; Shimizu, Kunihiko; Shoin, Wataru; Harada, Mikiko; Mochidome, Tomoaki; Senda, Keisuke; Yoshie, Koji; Oguchi, Yasutaka; Hashizume, Naoto; Abe, Naoyuki; Saigusa, Tatsuya; Ebisawa, Soichiro; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;
CIRCULATION JOURNAL, 82(6), 1614-+, 2018年06月

Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report
Nakagawa, Yasuaki; Nishikimi, Toshio; Sakai, Hiroshi; Ohno, Seiko; Kinoshita, Hideyuki; Inazumi, Hideaki; Moriuchi, Kenji; Kuwahara, Koichiro; Horie, Minoru; Kimura, Takeshi;
CLINICAL BIOCHEMISTRY, 52, 148-152, 2018年02月

Drug-Eluting Versus Bare-Metal Stent Implantation with or without Cilostazol in the Treatment of the Superficial Femoral Artery
Miura T, Miyashita Y, Soga Y, Hozawa K, Doijiri T, Ikeda U, Kuwahara K on behalf of the DEBATE in SFA investigators
Circ Cardiovasc Interv, 11(8), e006564, 2018年

Cutting Edge of Brain Natriuretic Peptide (BNP) Research - The Diversity of BNP Immunoreactivity and Its Clinical Relevance
Kuwahara K, Nakagawa Y, Nishikimi T
Circ J, 82(10), 2455-2461, 2018年

T-wave alternans in a case with systemic lupus erythematosus-related myocarditis
Harada M, Motoki H, Kashima Y, Nakamura C, Hashizume N, Kishida D, Imamura H, Kuwahara K
J Cardiol Cases, 18(4), 119-122, 2018年

Duration of myocardial early systolic lengthening for diagnosis of coronary artery disease
Minamisawa M, Koyama J, Kozuka A, Miura T, Saigusa T, Ebisawa S, Motoki H, Okada A, Ikeda U, Kuwahara K
Open Heart, 5, e000896, 2018年

Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan - Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry
Yaku H, Ozasa N, Morimoto T, Inuzuka Y, Tamaki Y, Yamamoto E, Yoshikawa Y, Kitai T, Taniguchi R, Iguchi M, Kato M, Takahashi M, Jinnai T, Ikeda T, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Su K, Kawato M, Sasaki K, Toyofuku M, Furukawa Y, Nakagawa Y, Ando K, Kadota K, Shizuta S, Ono K, Sato Y, Kuwahara K, Kato T, Kimura T, on behalf of the KCHF Study Investigators
Circ J, 82(11), 2811-2819, 2018年

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence
Nishimura A, Shimauchi T, Tanaka T, Shimoda K, Toyama T, Kitajima N, Ishikawa T, Shindo N, Numaga-Tomita T, Yasuda S, Sato Y, Kuwahara K, Kumagai Y, Akaike T, Ide T, Ojida A, Mori Y, Nishida M
Sci Signal, 11(556), eaat5185, 2018年

Cross-sectional study of the association between day-to-day home blood pressure variability and visceral fat area measured using the dual impedance method
Kuwabara J, Kuwahara K, Kuwabara Y, Yasuno S, Nakagawa Y, Ueshima K, Kimura T
PLOS ONE, 13(11), e0206945, 2018年

Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death
Fujii, Toshihito; Hirota, Keisho; Yasoda, Akihiro; Takizawa, Akiko; Morozumi, Naomi; Nakamura, Ryuichi; Yotsumoto, Takafumi; Kondo, Eri; Yamashita, Yui; Sakane, Yoriko; Kanai, Yugo; Ueda, Yohei; Yamauchi, Ichiro; Yamanaka, Shigeki; Nakao, Kazumasa; Kuwahara, Koichiro; Jindo, Toshimasa; Furuya, Mayumi; Mashimo, Tomoji; Inagaki, Nobuya; Serikawa, Tadao; Nakao, Kazuwa;
PLOS ONE, 13(3), 2018年

CHARACTERISTIC AND CLINICAL OUTCOMES IN PATIENTS WITH LEFT VENTRICULAR NONCOMPACTION IN ADULTS: A NATIONWIDE SURVEY IN JAPAN
Minamisawa, Masatoshi; Koyama, Jun; Kuwahara, Koichiro; Ikeda, Uichi;
Journal of the American College of Cardiology, 71(11), 714-714, 2018年

Single-center experience with percutaneous lead extraction of cardiac implantable electric devices
Okada, Ayako; Shoda, Morio; Tabata, Hiroaki; Shoin, Wataru; Kobayashi, Hideki; Okano, Takahiro; Yoshie, Koji; Oguchi, Yasutaka; Takeuchi, Takahiro; Kato, Ken; Kuwahara, Koichiro;
Journal of cardiology, 71(1-2), 192-196, 2018年

内科学第五教室
桑原 宏一郎
信州医学雑誌, 66(3), 226-226, 2018年

深部静脈血栓症を疑って施行された下肢静脈超音波検査の有病率に関する検討
山崎 佐枝子;元木 博彦;桑原 宏一郎;三浦 崇;千田 啓介;酒井 貴弘;小口 泰尚;加藤 太門;三枝 達也;海老澤 聡一朗;岡田 綾子
脈管学, 58(9), 145-149, 2018年

心不全バイオマーカーとしてのBNPの臨床的意義
桑原 宏一郎;
診断と治療 = Diagnosis and treatment, 105(12), 1603-1607, 2017年12月

Prognostic Value of Ankle-Brachial Index in Patients Undergoing Percutaneous Coronary Intervention: In-Hospital and 1-Year Outcomes From the SHINANO Registry
Hashizume, Naoto; Miura, Takashi; Miyashita, Yusuke; Motoki, Hirohiko; Ebisawa, Soichiro; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro; SHINANO Registry Investigators;
Angiology, 68(10), 884-892, 2017年11月

Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension
Tanabe, Nobuhiro; Ikeda, Satoshi; Tahara, Nobuhiro; Fukuda, Keiichi; Hatano, Masaru; Ito, Hiroshi; Nakayama, Tomotaka; Anzai, Toshihisa; Hashimoto, Akiyoshi; Inoue, Teruo; Kajinami, Kouji; Kihara, Yasuki; Kinoshita, Hideyuki; Kuwahara, Koichiro; Murohara, Toyoaki; Okazaki, Osamu; Sakai, Satoshi; Satoh, Toru; Takeda, Yutaka; Takeishi, Yasuchika; Taniguchi, Mitsugu; Watanabe, Hiroshi; Yamamoto, Takeshi; Yamauchi-Takihara, Keiko; Yoshioka, Koichiro; Sasayama, Shigetake;
CIRCULATION JOURNAL, 81(9), 1360-1367, 2017年09月

Cardiac hyaluronan may be associated with the persistence of atrial fibrillation
Okada, Ayako; Kashima, Yuichiro; Tomita, Takeshi; Takeuchi, Takahiro; Oguchi, Yasutaka; Yoshie, Koji; Shoin, Wataru; Shoda, Morio; Nitta, Kenichi; Kuwahara, Koichiro; Imamura, Hiroshi;
Heart and Vessels, 32(9), 1144-1150, 2017年09月

Omecamtiv mecarbil
木村 和広; 桑原 宏一郎;
循環器内科 = Cardioangiology, 82(2), 169-172, 2017年08月

B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction
Harada, Eisaku; Mizuno, Yuji; Kugimiya, Fumihito; Shono, Makoto; Maeda, Hiroyuki; Yano, Naotsugu; Kuwahara, Koichiro; Yasue, Hirofumi;
CIRCULATION JOURNAL, 81(7), 1006-+, 2017年07月

Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model
Setozaki, Shuji; Minakata, Kenji; Masumoto, Hidetoshi; Hirao, Shingo; Yamazaki, Kazuhiro; Kuwahara, Koichiro; Ikeda, Tadashi; Sakata, Ryuzo;
JOURNAL OF VASCULAR SURGERY, 65(6), 1803-1812, 2017年06月

Kyoto Congestive Heart Failure (KCHF) study: rationale and design
Yamamoto, Erika; Kato, Takao; Ozasa, Neiko; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Kitai, Takeshi; Morimoto, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawashima, Tsuneaki; Motohashi, Yasuyo; Kawato, Mitsunori; Toyofuku, Mamoru; Sato, Yukihito; Kuwahara, Koichiro; Shioi, Tetsuo; Kimura, Takeshi
ESC HEART FAILURE, 4(3), 216-223, 2017年02月17日

MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts
Nakagawa, Yasuaki; Nishikimi, Toshio; Kuwahara, Koichiro; Fujishima, Aoi; Oka, Shogo; Tsutamoto, Takayoshi; Kinoshita, Hideyuki; Nakao, Kazuhiro; Cho, Kosai; Inazumi, Hideaki; Okamoto, Hiroyuki; Nishida, Motohiro; Kato, Takao; Fukushima, Hiroyuki; Yamashita, Jun K.; Wijnen, Wino J.; Creemers, Esther E.; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa; Kimura, Takeshi
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 6(2), 2017年02月10日

Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity.
Nakao K, Kuwahara K, Nishikimi T, Nakagawa Y, Kinoshita H, Minami T, Kuwabara Y, Yamada C, Yamada Y, Tokudome T, Nagai-Okatani C, Minamino N, Nakao YM, Yasuno S, Ueshima K, Sone M, Kimura T, Kangawa K, Nakao K.
Hypertension, 69(2), 286-296, 2017年02月

Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy.
Mori KP, Yokoi H, Kasahara M, Imamaki H, Ishii A, Kuwabara T, Koga K, Kato Y, Toda N, Ohno S, Kuwahara K, Endo T, Nakao K, Yanagita M, Mukoyama M, Mori K.
J Am Soc Nephrol, 28(1), 278-289, 2017年01月

Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model
Ogasawara, Tatsuki; Okano, Satomi; Ichimura, Hajime; Kadota, Shin; Tanaka, Yuki; Minami, Itsunari; Uesugi, Motonari; Wada, Yuko; Saito, Naoto; Okada, Kenji; Kuwahara, Koichiro; Shiba, Yuji;
SCIENTIFIC REPORTS, 7, 2017年

Diagnostic advantage of stress computed tomography myocardial perfusion over single-photon emission computed tomography for the assessment of myocardial ischemia
Ueki, Yasushi; Izawa, Atsushi; Kashiwagi, Daisuke; Nishiyama, Shigeki; Aso, Shinichi; Suzuki, Chihiro; Sakurai, Shumpei; Oguchi, Kazuhiro; Yazaki, Yoshikazu; Ikeda, Uichi; Kuwahara, Koichiro;
Journal of cardiology, 70(1-2), 147-154, 2017年

Impressive predictive value of ankle-brachial index for very long-term outcomes in patients with cardiovascular disease: IMPACT-ABI study
Miura, Takashi; Minamisawa, Masatoshi; Ueki, Yasushi; Abe, Naoyuki; Nishimura, Hitoshi; Hashizume, Naoto; Mochidome, Tomoaki; Harada, Mikiko; Oguchi, Yasutaka; Yoshie, Koji; Shoin, Wataru; Saigusa, Tatsuya; Ebisawa, Soichiro; Motoki, Hirohiko; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;
PLOS ONE, 12(6), 2017年

Ankle-brachial index for the prognosis of cardiovascular disease in patients with mild renal insufficiency
Nishimura, Hitoshi; Miura, Takashi; Minamisawa, Masatoshi; Ueki, Yasushi; Abe, Naoyuki; Hashizume, Naoto; Mochidome, Tomoaki; Harada, Mikiko; Shimizu, Kunihiko; Shoin, Wataru; Yoshie, Koji; Oguchi, Yasutaka; Ebisawa, Soichiro; Motoki, Hirohiko; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;
INTERNAL MEDICINE, 56(16), 2103-2111, 2017年

2-Year Natural History of Lower Limbs in Patients With End-stage Renal Disease on Hemodialysis Due to Diabetic Nephropathy; From PREDICT Study
Kato, Tamon; Miyashita, Yusuke; Miura, Takashi; Ebisawa, Souitirou; Saigusa, Tatsuya; Kuwahara, Koichiro;
Journal of the American College of Cardiology, 70(18), B71-B71, 2017年

心不全診療におけるナトリウム利尿ペプチドの臨床応用のインパクト
桑原 宏一郎
心臓, 49(8), 795-795, 2017年

ナトリウム利尿ペプチドが変えた循環器診療
桑原 宏一郎
信州医学雑誌, 65(5), 247-248, 2017年

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.
Numaga-Tomita T, Kitajima N, Kuroda T, Nishimura A, Miyano K, Yasuda S, Kuwahara K, Sato Y, Ide T, Birnbaumer L, Sumimoto H, Mori Y, Nishida M.
Sci Rep, 6, 39383, 2016年12月

【循環器疾患治療薬:薬の使い方、どこまで理解していますか?】 循環器薬を識る　利尿薬　バソプレシンV2受容体拮抗薬、hANP含む
桑原宏一郎, 木村剛
Heart View, 20(12), 16-20, 2016年11月

Brain Natriuretic Peptide Counteracting the Renin-angiotensin-aldosterone System in Accelerated Malignant Hypertension.
Nakagawa H, Mizuno Y, Harada E, Morikawa Y, Kuwahara K, Saito Y, Yasue H.
Am J Med Sci, 352(5), 534-539, 2016年11月

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.
Kitajima N, Numaga-Tomita T, Watanabe M, Kuroda T, Nishimura A, Miyano K, Yasuda S, Kuwahara K, Sato Y, Ide T, Birnbaumer L, Sumimoto H, Mori Y, Nishida M.
Sci Rep, 6, 37001, 2016年11月

僧帽弁逆流の成因解明にストレインエコーが有用であった心臓サルコイドーシスの一症例
米田智也, 木下秀之, 半田知宏, 長井苑子, 相澤卓範, 岡林真梨恵, 中島康弘, 中川靖章, 桑原宏一郎, 一山智, 木村剛
日本サルコイドーシス/肉芽腫性疾患学会雑誌, 36(1-2), 79-83, 2016年10月

Brain-specific natriuretic peptide receptor-B deletion attenuates high-fat diet-induced visceral and hepatic lipid deposition in mice.
Yamashita Y, Yamada-Goto N, Katsuura G, Ochi Y, Kanai Y, Miyazaki Y, Kuwahara K, Kanamoto N, Miura M, Yasoda A, Ohinata K, Inagaki N, Nakao K.
PEPTIDES, 81, 38-50, 2016年07月

Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure.
Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, Naito M, Kuwabara T, Imamaki H, Ishii A, Saleem MA, Numata T, Mori Y, Nakao K, Yanagita M, Mukoyama M.
Sci Rep, 6, 27192, 2016年06月

Secretion of ProBNP is Regulated by Mir30-GALNTs Axis Dependent O-linked Glycosylation in the Pathological Myocardium
Nakagawa, Yasuaki; Kuwahara, Koichiro; Nishikimi, Toshio; Kinoshita, Hideyuki; Inazumi, Hideki; Moriuchi, Kenji; Kato, Takao; Minamino, Naoto; Nacho, Kazuwa; Kimura, Takeshi;
Circulation, 134, 2016年

The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy
Yamada, Chinatsu; Kuwahara, Koichiro; Yamazaki, Masatoshi; Nakagawa, Yasuaki; Nishikimi, Toshio; Kinoshita, Hideyuki; Kuwabara, Yoshihiro; Minami, Takeya; Yamada, Yuko; Shibata, Junko; Nakao, Kazuhiro; Cho, Kosai; Arai, Yuji; Honjo, Haruo; Kamiya, Kaichiro; Nakao, Kazuwa; Kimura, Takeshi;
Cardiovascular Research, 109(1), 162-173, 2016年

【新しい循環器病のバイオマーカー-臨床的意義を理解する-】 循環器疾患における各種バイオマーカーの意義　BNP
桑原宏一郎, 木村剛
Heart View, 19(12), 205-208, 2015年11月

PAHに伴う心肺病変について考えるシンポジウム 軽症PHを有する強皮症に対する病態評価と治療介入の是非　私はこのように対処している　自験例の紹介　京都大学での経験
木下秀之, 桑原宏一郎
Pulmonary Hypertension Update, 1(Suppl.), 155-160, 2015年10月

Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites.
Nishikimi T, Nakagawa Y, Minamino N, Ikeda M, Tabei K, Fujishima A, Takayama K, Akimoto K, Yamada C, Nakao K, Minami T, Kuwabara Y, Kinoshita H, Tsutamoto T, Ishimitsu T, Kangawa K, Kuwahara K, Nakao K.
Am J Physiol Regul Integr Comp Physiol, 309(6), R639-49, 2015年09月

【心不全に対する多面的治療戦略-基礎から臨床へ-】 心不全におけるエピジェネティクス制御とその新規治療標的としての意義
桑原宏一郎, 木村剛
循環器内科, 78(2), 145-148, 2015年08月

The organ-protective effect of N-type Ca(2+) channel blockade.
Kuwahara K, Kimura T.
Pharmacol Ther, 151, 1-7, 2015年07月

【肥満と循環器病】 肥満と虚血性心疾患
桑原宏一郎, 木村剛
循環器内科, 77(6), 519-522, 2015年06月

心血管疾患の病態と治療における最新知見　ナトリウム利尿ペプチドの心保護作用
桑原宏一郎, 木村剛, 中尾一和
循環plus, 15(8), 7-9, 2015年05月

The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth.
Nakao K, Osawa K, Yasoda A, Yamanaka S, Fujii T, Kondo E, Koyama N, Kanamoto N, Miura M, Kuwahara K, Akiyama H, Bessho K, Nakao K.
Sci Rep, 5, 10554, 2015年05月

Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2.
Oshita K, Itoh M, Hirashima S, Kuwabara Y, Ishihara K, Kuwahara K, Nakao K, Kimura T, Nakamura K, Ushijima K, Takano M.
J Mol Cell Cardiol, 80, 81-9, 2015年03月

Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model.
Tanaka M, Yamaguchi S, Yamazaki Y, Kinoshita H, Kuwahara K, Nakao K, Jay PY, Noda T, Nakamura T.
Sci Rep, 5, 7826, 2015年01月

Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure.
Nakagawa Y, Yasuno S, Kuwahara K.
Circ J, 79(9), 1893-4, 2015年

The Effects of Super-Flux (High Performance) Dialyzer on Plasma Glycosylated Pro-B-Type Natriuretic Peptide (proBNP) and Glycosylated N-Terminal proBNP in End-Stage Renal Disease Patients on Dialysis
Nakagawa, Yasuaki; Nishikimi, Toshio; Kuwahara, Koichiro; Yasuno, Shinji; Kinoshita, Hideyuki; Kuwabara, Yoshihiro; Nakao, Kazuhiro; Minami, Takeya; Yamada, Chinatsu; Ueshima, Kenji; Ikeda, Yoshihiro; Okamoto, Hiroyuki; Horii, Kazukiyo; Nagata, Kiyoshi; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa
PLOS ONE, 9(3), 2014年03月25日

Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure
Yamada, Yuko; Kinoshita, Hideyuki; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kuwabara, Yoshihiro; Minami, Takeya; Yamada, Chinatsu; Shibata, Junko; Nakao, Kazuhiro; Cho, Kosai; Arai, Yuji; Yasuno, Shinji; Nishikimi, Toshio; Ueshima, Kenji; Kamakura, Shiro; Nishida, Motohiro; Kiyonaka, Shigeki; Mori, Yasuo; Kimura, Takeshi; Kangawa, Kenji; Nakao, Kazuwa;
Cardiovascular Research, 104(1), 183-193, 2014年

Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy
Yasuno, Shinji; Kuwahara, Koichiro; Kinoshita, Hideyuki; Yamada, Chinatsu; Nakagawa, Yasuaki; Usami, Satoru; Kuwabara, Yoshihiro; Ueshima, Kenji; Harada, Masaki; Nishikimi, Toshio; Nakao, Kazuwa;
British Journal of Pharmacology, 170(7), 1384-1395, 2013年12月

Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts
Kuwabara, Yoshihiro; Kuwahara, Koichiro; Takano, Makoto; Kinoshita, Hideyuki; Arai, Yuji; Yasuno, Shinji; Nakagawa, Yasuaki; Igata, Sachiyo; Usami, Satoru; Minami, Takeya; Yamada, Yuko; Nakao, Kazuhiro; Yamada, Chinatsu; Shibata, Junko; Nishikimi, Toshio; Ueshima, Kenji; Nakao, Kazuwa;
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2(3), 2013年06月

Adrenomedullin in Cardiovascular Disease: A Useful Biomarker, its Pathological Roles and Therapeutic Application
Nishikimi, Toshio; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kangawa, Kenji; Nakao, Kazuwa;
CURRENT PROTEIN & PEPTIDE SCIENCE, 14(4), 256-267, 2013年06月

Complexity of molecular forms of B-type natriuretic peptide in heart failure
Nishikimi, Toshio; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa;
HEART, 99(10), 677-679, 2013年05月

Direct Immunochemiluminescent Assay for proBNP and Total BNP in Human Plasma proBNP and Total BNP Levels in Normal and Heart Failure
Nishikimi, Toshio; Okamoto, Hiroyuki; Nakamura, Masahiro; Ogawa, Naoko; Horii, Kazukiyo; Nagata, Kiyoshi; Nakagawa, Yasuaki; Kinoshita, Hideyuki; Yamada, Chinatsu; Nakao, Kazuhiro; Minami, Takeya; Kuwabara, Yoshihiro; Kuwahara, Koichiro; Masuda, Izuru; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa;
PLOS ONE, 8(1), 2013年

Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice
Nishida, Motohiro; Ishikawa, Tatsuya; Saiki, Shota; Sunggip, Caroline; Aritomi, Shizuka; Harada, Eri; Kuwahara, Koichiro; Hirano, Katsuya; Mori, Yasuo; Kim-Mitsuyama, Shokei;
Biochemical and biophysical research communications, 434(2), 210-216, 2013年

Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice
Minami, Takeya; Kuwahara, Koichiro; Nakagawa, Yasuaki; Takaoka, Minoru; Kinoshita, Hideyuki; Nakao, Kazuhiro; Kuwabara, Yoshihiro; Yamada, Yuko; Yamada, Chinatsu; Shibata, Junko; Usami, Satoru; Yasuno, Shinji; Nishikimi, Toshio; Ueshima, Kenji; Sata, Masataka; Nakano, Hiroyasu; Seno, Takahiro; Kawahito, Yutaka; Sobue, Kenji; Kimura, Akinori; Nagai, Ryozo; Nakao, Kazuwa;
EMBO JOURNAL, 31(23), 4428-4440, 2012年

Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
Hata, Leo; Murakami, Masao; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kinoshita, Hideyuki; Usami, Satoru; Yasuno, Shinji; Fujiwara, Masataka; Kuwabara, Yoshihiro; Minami, Takeya; Yamada, Yuko; Yamada, Chinatsu; Nakao, Kazuhiro; Ueshima, Kenji; Nishikimi, Toshio; Nakao, Kazuwa;
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 50(6), 972-981, 2011年06月

Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A
Fujiwara, Masataka; Yan, Peishi; Otsuji, Tomomi G.; Narazaki, Genta; Uosaki, Hideki; Fukushima, Hiroyuki; Kuwahara, Koichiro; Harada, Masaki; Matsuda, Hiroyuki; Matsuoka, Satoshi; Okita, Keisuke; Takahashi, Kazutoshi; Nakagawa, Masato; Ikeda, Tadashi; Sakata, Ryuzo; Mummery, Christine L.; Nakatsuji, Norio; Yamanaka, Shinya; Nakao, Kazuwa; Yamashita, Jun K.;
PLOS ONE, 6(2), 2011年

Pathophysiological Remodeling of Mouse Cardiac Myocytes Expressing Dominant Negative Mutant of Neuron Restrictive Silencing Factor
Takano, Makoto; Kinoshita, Hideyuki; Shioya, Takao; Itoh, Masayuki; Nakao, Kazuwa; Kuwahara, Koichiro;
CIRCULATION JOURNAL, 74(12), 2712-2719, 2010年12月

Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression
Kuwahara, Koichiro; Kinoshita, Hideyuki; Kuwabara, Yoshihiro; Nakagawa, Yasuaki; Usami, Satoru; Minami, Takeya; Yamada, Yuko; Fujiwara, Masataka; Nakao, Kazuwa;
MOLECULAR AND CELLULAR BIOLOGY, 30(17), 4134-4148, 2010年09月

Regulation and significance of atrial and brain natriuretic peptides as cardiac hormones
Kuwahara, Koichiro; Nakao, Kazuwa;
Endocrine journal, 57(7), 555-565, 2010年07月

Podocyte-specific expression of tamoxifen-inducible Cre recombinase in mice
Yokoi, Hideki; Kasahara, Masato; Mukoyama, Masashi; Mori, Kiyoshi; Kuwahara, Koichiro; Fujikura, Junji; Arai, Yuji; Saito, Yoko; Ogawa, Yoshihisa; Kuwabara, Takashige; Sugawara, Akira; Nakao, Kazuwa;
NEPHROLOGY DIALYSIS TRANSPLANTATION, 25(7), 2120-2124, 2010年07月

Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction
Small, Eric M.; Thatcher, Jeffrey E.; Sutherland, Lillian B.; Kinoshita, Hideyuki; Gerard, Robert D.; Richardson, James A.; DiMaio, J. Michael; Sadek, Hesham; Kuwahara, Koichiro; Olson, Eric N.;
Circulation Research, 107(2), 294-U263, 2010年

Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart
Kinoshita, Hideyuki; Kuwahara, Koichiro; Nishida, Motohiro; Jian, Zhong; Rong, Xianglu; Kiyonaka, Shigeki; Kuwabara, Yoshihiro; Kurose, Hitoshi; Inoue, Ryuji; Mori, Yasuo; Li, Yuhao; Nakagawa, Yasuaki; Usami, Satoru; Fujiwara, Masataka; Yamada, Yuko; Minami, Takeya; Ueshima, Kenji; Nakao, Kazuwa;
Circulation Research, 106(12), 1849-U153, 2010年

Guanylyl Cyclase-A Inhibits Angiotensin II Type 2 Receptor-Mediated Pro-Hypertrophic Signaling in the Heart
Li, Yuhao; Saito, Yoshihiko; Kuwahara, Koichiro; Rong, Xianglu; Kishimoto, Ichiro; Harada, Masaki; Adachi, Yuichiro; Nakanishi, Michio; Kinoshita, Hideyuki; Horiuchi, Masatsugu; Murray, Michael; Nakao, Kazuwa;
Endocrinology, 150(8), 3759-3765, 2009年08月

p300 Plays a Critical Role in Maintaining Cardiac Mitochondrial Function and Cell Survival in Postnatal Hearts
Nakagawa, Yasuaki; Kuwahara, Koichiro; Takemura, Genzo; Akao, Masaharu; Kato, Masashi; Arai, Yuji; Takano, Makoto; Harada, Masaki; Murakami, Masao; Nakanishi, Michio; Usami, Satoru; Yasuno, Shinji; Kinoshita, Hideyuki; Fujiwara, Masataka; Ueshima, Kenji; Nakao, Kazuwa;
Circulation Research, 105(8), 746-U57, 2009年

T-Type Ca2+ Channel Blockade Prevents Sudden Death in Mice With Heart Failure
Kinoshita, Hideyuki; Kuwahara, Koichiro; Takano, Makoto; Arai, Yuji; Kuwabara, Yoshihiro; Yasuno, Shinji; Nakagawa, Yasuaki; Nakanishi, Michio; Harada, Masaki; Fujiwara, Masataka; Murakami, Masao; Ueshima, Kenji; Nakao, Kazuwa;
Circulation, 120(9), 743-U66, 2009年

The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2
Kuratomi, Shinobu; Ohmori, Yoko; Ito, Masayuki; Shimazaki, Kuniko; Muramatsu, Shin-ichi; Mizukami, Hiroaki; Uosaki, Hideki; Yamashita, Jun K.; Arai, Yuji; Kuwahara, Koichiro; Takano, Makoto;
Cardiovascular Research, 83(4), 682-687, 2009年

Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation
Nakanishi, Michio; Harada, Masaki; Kishimoto, Ichiro; Kuwahara, Koichiro; Kawakami, Rika; Nakagawa, Yasuaki; Yasuno, Shinji; Usami, Satoru; Kinoshita, Hideyuki; Adachi, Yuichiro; Fukamizu, Akiyoshi; Saito, Yoshihiko; Nakao, Kazuwa;
CIRCULATION JOURNAL, 71(8), 1310-1316, 2007年08月

Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity
Kuwahara, Koichiro; Pipes, Gordon C. Teg; McAnally, John; Richardson, James A.; Hill, Joseph A.; Bassel-Duby, Rhonda; Olson, Eric N.;
JOURNAL OF CLINICAL INVESTIGATION, 117(5), 1324-1334, 2007年05月

Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance
Nakanishi, Michio; Harada, Masaki; Tadamura, Eiji; Kotani, Hirokazu; Kawakami, Rika; Kuwahara, Koichiro; Nakagawa, Yasuaki; Usami, Satoru; Kinoshita, Hideyuki; Fujiwara, Masataka; Hosoda, Kiminori; Ueshima, Kenji; Nakao, Kazuwa;
Circulation, 116(2), E25-E26, 2007年

Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin
Barrientos, Tomasa; Frank, Derk; Kuwahara, Koichiro; Bezprozvannaya, Svetlana; Pipes, G. C. Teg; Bassel-Duby, Rhonda; Richardson, James A.; Katus, Hugo A.; Olson, Eric N.; Frey, Norbert;
JOURNAL OF BIOLOGICAL CHEMISTRY, 282(11), 8393-8403, 2007年

Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes
Nakagawa, Yasuaki; Kuwahara, Koichiro; Harada, Masaki; Takahashi, Nobuki; Yasuno, Shinji; Adachi, Yuichiro; Kawakami, Rika; Nakanishi, Michio; Tanimoto, Keiji; Usami, Satoru; Kinoshita, Hideyuki; Saito, Yoshihiko; Nakao, Kazuwa;
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 41(6), 1010-1022, 2006年12月

TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
Kuwahara, Koichiro; Wang, Yanggan; McAnally, John; Richardson, James A.; Bassel-Duby, Rhonda; Hill, Joseph A.; Olson, Eric N.;
JOURNAL OF CLINICAL INVESTIGATION, 116(12), 3114-3126, 2006年12月

重症PAHにおける肺移植術後急性期の右室および左室機能の検討
米田智也, 木下秀之, 中島康弘, 本山秀樹, 土屋恭子, 青山晃博, 陳豊史, 桑原宏一郎, 木村剛, 伊達洋至, 一山智
呼吸と循環 64 5 S57, 2016年05月

低酸素血症を伴う重症特発性肺動脈性肺高血圧症患者の臨床経過
相澤卓範, 木下秀之, 中西直彦, 桜井孝規, 今井逸雄, 中川靖章, 静田聡, 桑原宏一郎, 青山晃博, 伊達洋至, 木村剛
呼吸と循環 64 5 S54, 2016年05月

重症肺高血圧症を合併した肺線維症と考えられた1症例
柳澤洋, 木下秀之, 佐藤雅昭, 桜井孝規, 半田知宏, 今井逸雄, 中川靖章, 静田聡, 桑原宏一郎, 伊達洋至, 木村剛
呼吸と循環 64 5 S52-S53, 2016年05月

膠原病関連肺高血圧症とCT所見
柳澤洋, 木下秀之, 吉藤元, 半田知宏, 藤井隆夫, 牧山武, 中川靖章, 静田聡, 桑原宏一郎, 三森経世, 木村剛
呼吸と循環 64 5 S46-S47, 2016年05月

当院におけるILD-PHに対する肺血管拡張療法の効果の検討
藤田啓誠, 木下秀之, 半田知宏, 谷澤公伸, 室繁郎, 佐藤晋, 山田千夏, 中川靖章, 静田聡, 桑原宏一郎, 木村剛
呼吸と循環 64 5 S42, 2016年05月

デュアルインピーダンス法による計測された内臓脂肪面積と自宅血圧の日間変動指標との関連の検討
桑原純子, 桑原宏一郎, 堀井和子, 桑原佳宏, 保野慎治, 保野明子, 藤永有理子, 中川靖章, 木下秀之, 山田千夏, 横井秀基, 曽根正勝, 上嶋健治, 中尾一和, 木村剛
日本高血圧学会臨床高血圧フォーラムプログラム・抄録集 5 165, 2016年05月

miR30-GALNT経路によるO型糖鎖修飾を介したBNPプロセシング調節が病的心筋からのproBNP分泌亢進に寄与する
中川靖章, 錦見俊雄, 桑原宏一郎, 保野慎治, 木下秀之, 桑原佳宏, 山田千夏, 稲住英明, 上嶋健治, 南野直人, 中尾一和, 木村剛
日本臨床分子医学会学術総会プログラム・抄録集 53 75, 2016年04月

O型糖転移酵素GALNTのBNPプロセシング調節への関与
中川靖章, 錦見俊雄, 桑原宏一郎, 木下秀之, 山田千夏, 稲住英明, 南野直人, 中尾一和, 木村剛
日本内分泌学会雑誌 92 1 256, 2016年04月

糖尿病性腎症におけるN型Ca2+チャネル阻害の腎保護効果
大野祥子, 横井秀基, 笠原正登, 森潔, 桑原宏一郎, 藤倉純二, 内藤雅喜, 桑原孝成, 菅原照, 柳田素子, 中尾一和, 向山政志
日本内分泌学会雑誌 92 1 212, 2016年04月

心不全患者におけるproBNPの分泌と代謝についての検討
中川靖章, 錦見俊雄, 桑原宏一郎, 木下秀之, 山田千夏, 南野直人, 中尾一和, 木村剛
日本内分泌学会雑誌 91 2 644, 2015年09月

O型糖鎖修飾を介したヒトBNPプロセシング調節に関与する糖転移酵素についての検討
中川靖章, 錦見俊雄, 桑原宏一郎, 木下秀之, 山田千夏, 南野直人, 中尾一和, 木村剛
日本内分泌学会雑誌 91 2 643, 2015年09月

肺高血圧症合併肺ランゲルハンス細胞組織球症に対する治療経過
柳澤洋, 木下秀之, 山田徹, 半田知宏, 中川靖章, 牧山武, 静田聡, 桑原宏一郎, 伊達洋至, 木村剛
呼吸と循環 63 8 S57, 2015年08月

肺血管拡張薬中止理由の検討と病棟専従薬剤師の役割の考察
吉田優子, 木下秀之, 吉田詩織, 木下美津子, 中川靖章, 牧山武, 静田聡, 桑原宏一郎, 木村剛, 松原和夫
呼吸と循環 63 8 S55-S56, 2015年08月

肺動脈性肺高血圧症における肺移植術後早期の左室機能の検討
米田智也, 木下秀之, 土井孝浩, 山田徹, 佐藤雅昭, 青山晃博, 陳豊史, 桑原宏一郎, 伊達洋至, 木村剛
呼吸と循環 63 8 S44, 2015年08月

糖尿病性腎症におけるN型Ca2+チャネル阻害の腎保護効果
大野祥子, 横井秀基, 笠原正登, 森潔, 桑原宏一郎, 藤倉純二, 内藤雅喜, 桑原孝成, 今牧博貴, 石井輝, 古賀健一, 塩田文彦, 沼田朋大, 菅原照, 森泰生, 中尾一和, 柳田素子, 向山政志
日本腎臓学会誌 57 3 569, 2015年04月

心不全に伴う不整脈源性基質形成におけるレニン・アンジオテンシン系の意義
桑原宏一郎
先進医薬研究振興財団研究成果報告集 2014 166-167, 2015年03月

シルニジピンによる糖尿病性腎症の進行抑制機序の検討
大野祥子, 横井秀基, 笠原正登, 森潔, 桑原宏一郎, 塩田文彦, 菅原照, 中尾一和, 柳田素子, 向山政志
日本内科学会雑誌 104 Suppl. 264, 2015年02月

心不全研究のカッティング・エッジ 心不全に伴う不整脈突然死発症にかかわる分子メカニズム
桑原宏一郎, 中尾一和, 木村剛
血管 38 1 26, 2015年01月

日本心臓リハビリテーション学会

日本内科学会

日本循環器学会

日本内分泌学会

日本心血管内分泌代謝学会

日本心不全学会

国際心臓研究学会日本部会

日本臨床分子医学会

日本肺高血圧・肺循環学会

日本糖尿病学会

日本心臓病学会

日本高血圧学会

日本心エコー図学会

日本生理学会

日本抗加齢医学会

日本不整脈心電学会

American Heart Association

European Society of Cardiology