KUWAHARA Koichiro

Academic Assembly School of Medicine and Health Sciences Institute of Medicine

School of Medicine Department of Medicine (Cardiovascular) 

Professor 

Field Of Study

  • Life sciences, Cardiology
  • Life sciences, Internal medicine - General
  • Life sciences, Metabolism and endocrinology
  • Life sciences, Genomics
  • Life sciences, Molecular biology
  • Cardiology, Cardiovascular Medicine, Molecular Cardiology,Cardiovascular Endocrinology and Metabolism

Career

  • 2023 - Present
    信州大学医学部附属病院, 脳卒中・心臓病等総合支援センター, センター長
  • 2023 - Present
    信州大学医学部附属病院先端心臓血管病センター, センター長
  • 2016 - Present
    信州大学医学部附属病院胸痛センター, センター長
  • 2016 - Present
    信州大学医学部, 循環器内科学教室(内科学第五教室), 教授
  • 2009 - 2016
    Kyoto University, 講師
  • 2009 - 2009
    京都大学大学院医学研究科, 特定講師
  • 2005 - 2009
    京都大学大学院医学研究科, 産学連携講師
  • 2003 - 2005
    テキサス大学サウスウエスタン医学研究所, 分子生物学講座, フェロー
  • 2003 - 2003
    京都大学大学院医学研究科, 臨床病態医科学, 医員
  • 2000 - 2003
    京都大学大学院医学研究科, 臨床病態医科学, 日本学術振興会特別研究員
  • 1999 - 2000
    京都大学大学院医学研究科, 臨床病態医科学, 医員
  • 1992 - 1995
    静岡市立静岡病院, 内科, 研修医
  • 1991 - 1992
    京都大学医学部附属病院, 内科, 研修医

Educational Background

  • 1999 - 1999, 京都大学大学院医学研究科, 臨床病態医科学
  • 1995 - 1999, Kyoto University, 大学院医学研究科博士課程(内科系専攻)
  • 1985 - 1991, Kyoto University, 医学部

Member History

  • 2023 - Present
    理事, 日本腫瘍循環器学会
  • 2023 - Present
    第89回・第90回日本循環器学会学術集会プログラム検討カテゴリー(心不全・心筋症・移植)メンバー, 日本循環器学会
  • 2022 - Present
    学術委員, 日本高血圧学会
  • 2022 - Present
    評議員, 日本高血圧学会
  • 2022 - Present
    国際交流委員会 委員, 日本心臓病学会
  • 2022 - Present
    総務/将来構想委員会 副委員長, 日本心臓病学会
  • 2022 - Present
    研究推進・若手医師育成員会副委員長, 日本心臓病学会
  • 2022 - Present
    理事, 日本心臓病学会
  • 2022 - Present
    埋込型VAD事後検証部会委員, 日本循環器学会
  • 2022 - Present
    心臓移植適応検討部会委員, 日本循環器学会
  • 2022 - Present
    渉外委員会委員(国際), 日本循環器学会
  • 2022 - Present
    ガイドライン部会委員, 日本循環器学会
  • 2021 - Present
    理事, 日本循環器協会
  • 2021 - 2022
    生涯教育委員, 日本内科学会
  • 2020 - Present
    評議員, 日本肺高血圧・肺循環器学会
  • 2020 - Present
    出版・編集委員会委員長, 日本心不全学会
  • 2020 - Present
    社員, 日本循環器学会
  • 2020 - Present
    BCVR基礎研究部会委員, 日本循環器学会
  • 2020 - 2022
    研究推進・若手医師育成員会委員, 日本心臓病学会
  • 2020 - 2020
    あり方委員会委員, 日本内科学会
  • 2019 - Present
    心アミロイドーシス調査研究WG委員, 日本循環器学会
  • 2018 - Present
    評議員, 日本腫瘍循環器学会
  • 2018 - Present
    評議員, 日本心臓リハビリテーション学会
  • 2018 - Present
    国内交流委員会委員, 日本心不全学会
  • 2018 - Present
    顕彰委員会委員, 日本心不全学会
  • 2018 - Present
    理事, 日本心不全学会
  • 2018 - 2020
    助成金選考委員, かなえ医薬財団
  • 2018 - 2020
    学術委員会委員, 日本心臓病学会
  • 2018 - 2019
    研究奨励選考委員, 日本心臓財団
  • 2018
    理事, 国際心臓研究学会(ISHR)日本部会
  • 2018
    学術委員会委員, 日本心不全学会
  • 2018
    評議員, 日本内科学会
  • 2017 - Present
    理事, 日本心血管内分泌代謝学会
  • 2017 - 2019
    専門医制度審議会委員, 日本内科学会
  • 2015 - 2018
    選考委員, ノバルティス科学振興財団
  • 2010 - Present
    評議員, 日本臨床分子医学会
  • 2007 - Present
    評議員, 日本内分泌学会

Award

  • 2015
    日本心不全学会, 学術賞
  • 2015
    日本臨床分子医学会, 学会賞
  • 2013
    日本心臓財団, 佐藤賞
  • 2010
    日本内分泌学会, 研究奨励賞
  • 2009
    日本心血管内分泌代謝学会, 第13回高峰譲吉研究奨励賞
  • 2005
    American Heart Association, New Investigator Travel Award
  • 2004
    日本循環器学会, 第14回八木賞
  • 2002
    Cardiovascular System Dynamics Society, Kiichi Sagawa Young Investigator Award Finalist
  • 2001
    日本心血管内分泌代謝学会, 若手研究者奨励賞
  • 2001
    American Heart Association, Melvin L. Marcus Young Investigator Award Finalist
  • 2001
    日本内分泌学会, 若手研究者奨励賞
  • 2001
    日本心脈管作動物質学会, 研究奨励賞
  • 2000
    日本循環器学会, 若手研究者奨励賞
  • 1999
    日本心不全学会, 若手研究者奨励賞
  • 1999
    日本臨床分子医学会, Academic Encouragement Award
    Koichiro Kuwahara

Paper

  • Impact of hyper-polypharmacy due to non-cardiovascular medications on long-term clinical outcomes following endovascular treatment for lower limb artery disease: A sub-analysis of the I-PAD Nagano registry.
    Tamon Kato; Masatoshi Minamisawa; Takashi Miura; Masafumi Kanai; Yushi Oyama; Naoto Hashizume; Daisuke Yokota; Minami Taki; Keisuke Senda; Ken Nishikawa; Tadamasa Wakabayashi; Koki Fujimori; Kenichi Karube; Takahiro Sakai; Minami Inoue; Hidetsugu Yoda; Daisuke Sunohara; Yoshiteru Okina; Hidetomo Nomi; Yusuke Kanzaki; Keisuke Machida; Daisuke Kashiwagi; Yasushi Ueki; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Hirohiko Motoki; Koichiro Kuwahara
    Journal of cardiology, Jul. 2024リポジトリ電子ジャーナル
  • Validation and Comparison of the Prognosis Predicting Ability of Inflammation-Based Scores Following Endovascular Treatment for Peripheral Artery Disease.
    Tadashi Itagaki; Soichiro Ebisawa; Tamon Kato; Takashi Miura; Yushi Oyama; Naoto Hashizume; Daisuke Yokota; Minami Taki; Keisuke Senda; Yoshiteru Okina; Tadamasa Wakabayashi; Kouki Fujimori; Kenichi Karube; Takahiro Sakai; Fumika Nomoto; Toshifumi Takamatsu; Kiu Tanaka; Tomoaki Mochidome; Tatsuya Saigusa; Hirohiko Motoki; Toshio Kasai; Uichi Ikeda; Koichiro Kuwahara
    Angiology, 75(6), 536-545, Jul. 2024リポジトリ電子ジャーナル
  • Efficacy and safety of remote cardiac rehabilitation in the recovery phase of cardiovascular diseases (RecRCR study): A multicenter, nonrandomized, and interventional trial in Japan.
    Hidetaka Itoh; Eisuke Amiya; Takahiro Jimba; Mai Shimbo; Koichi Narita; Masanobu Taya; Toshiaki Kadokami; Takanori Yasu; Hideki Oka; Masakazu Sogawa; Hiroyoshi Yokoi; Kazuo Mizutani; Shin-Ichiro Miura; Tatsuo Tokeshi; Ayumi Date; Takahisa Noma; Daisuke Kutsuzawa; Soichiro Usui; Shigeo Sugawara; Masanori Kanazawa; Hisakuni Sekino; Miho Nishitani Yokoyama; Takahiro Okumura; Yusuke Ugata; Shinichiro Fujishima; Kagami Hirabayashi; Yuta Ishizaki; Koichiro Kuwahara; Yuko Kaji; Hiroki Shimizu; Teruyuki Koyama; Hitoshi Adachi; Yoko Kurumatani; Ryoji Taniguchi; Katsuhiko Ohori; Hirokazu Shiraishi; Takashi Hasegawa; Shigeru Makita; Issei Komuro; Yutaka Kimura
    International journal of cardiology. Heart & vasculature, 52, 101421-101421, Jun. 2024リポジトリ電子ジャーナル
  • Balcinrenone plus dapagliflozin in patients with heart failure and chronic kidney disease: Results from the phase 2b MIRACLE trial.
    Carolyn S P Lam; Lars Køber; Koichiro Kuwahara; Lars H Lund; Patrick B Mark; Linda G Mellbin; Morten Schou; Patricia Ely Pizzato; Anders Gabrielsen; Samvel B Gasparyan; Alessandro Ghiretti; Judith Hartleib-Geschwindner; Greggory J Housler; Paolo Fanti; Maria Leonsson-Zachrisson; John J V McMurray; Scott D Solomon
    European journal of heart failure, May 2024リポジトリ電子ジャーナル
  • Development of interpretable machine learning models to predict in-hospital prognosis of acute heart failure patients.
    Munekazu Tanaka; Hirohiko Kohjitani; Erika Yamamoto; Takeshi Morimoto; Takao Kato; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Masayuki Shiba; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Yasushi Okuno; Takeshi Kimura; Koh Ono
    ESC heart failure, May 2024リポジトリ電子ジャーナル
  • Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell-Derived Cardiac Spheroids.
    Hideki Kobayashi; Shugo Tohyama; Hajime Ichimura; Noburo Ohashi; Shuji Chino; Yusuke Soma; Hidenori Tani; Yuki Tanaka; Xiao Yang; Naoko Shiba; Shin Kadota; Kotaro Haga; Taijun Moriwaki; Yuika Morita-Umei; Tomohiko C Umei; Otoya Sekine; Yoshikazu Kishino; Hideaki Kanazawa; Hiroyuki Kawagishi; Mitsuhiko Yamada; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
    Circulation, Apr. 2024, Refereedリポジトリ電子ジャーナル
  • Oral nutritional supplements in older outpatients with heart failure: rationale and design of the ALIMENT-HF trial.
    Yudai Fujimoto; Taishi Dotare; Emi Maekawa; Kentaro Kamiya; Takeshi Kitai; Koichiro Kuwahara; Teruyasu Sugano; Masaaki Konishi; Tomohito Ohtani; Yoko Sakamoto; Kentaro Jujo; Chiharu Noda; Junya Ako; Naotake Yanagisawa; Yuya Matsue
    ESC heart failure, Apr. 2024リポジトリ電子ジャーナル
  • Two different right ventricular pacing waveforms.
    Toshinori Komatsu; Ayako Okada; Koichiro Kuwahara
    European heart journal. Case reports, 8(3), ytae119, Mar. 2024リポジトリ電子ジャーナル
  • Impact of Low Bone Mineral Content Index on Cardiovascular Outcomes in Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention.
    Tadashi Itagaki; Yasushi Ueki; Daisuke Sunohara; Moeko Aoki; Fumika Nomoto; Toshifumi Takamatsu; Tomoaki Mochidome; Takashi Miura; Toshio Kasai; Koichiro Kuwahara; Uichi Ikeda
    Angiology, 33197231226348-33197231226348, Jan. 2024リポジトリ電子ジャーナル
  • Successful Management of a Pregnant Patient with Danon Cardiomyopathy.
    Wataru Inoue; Hirohiko Motoki; Koji Yoshie; Koichiro Kuwahara
    Internal medicine (Tokyo, Japan), 63(5), 681-686, 2024リポジトリ電子ジャーナル
  • Clinical Profile and Prognosis of Dementia in Patients With Acute Decompensated Heart Failure - From the CURE-HF Registry.
    Keisuke Machida; Masatoshi Minamisawa; Hirohiko Motoki; Kanako Teramoto; Yukari Okuma; Masafumi Kanai; Kazuhiro Kimura; Takahiro Okano; Yasushi Ueki; Koji Yoshie; Tamon Kato; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Koichiro Kuwahara
    Circulation journal : official journal of the Japanese Circulation Society, 88(1), 93-102, Dec. 2023リポジトリ電子ジャーナル
  • Efficacy and Safety of Esaxerenone in Hypertensive Patients with Diabetes Mellitus Undergoing Treatment with Sodium-Glucose Cotransporter 2 Inhibitors (EAGLE-DH).
    Hirohiko Motoki; Yoshito Inobe; Toshiki Fukui; Arata Iwasaki; Shinya Hiramitsu; Sekiya Koyama; Izuru Masuda; Noriyuki Sekimura; Kazuya Yamamoto; Ai Sato; Mitsuhisa Komatsu; Takashi Taguchi; Kazuhito Shiosakai; Kotaro Sugimoto; Koichiro Kuwahara
    Advances in therapy, 40(11), 5055-5075, Nov. 2023リポジトリ電子ジャーナル
  • Recommendation for Appropriate Use of Sodium Glucose Cotransporter 2 Inhibitors in Treatment of Heart Failure.
    Atsushi Tanaka; Koichiro Kinugawa; Koichiro Kuwahara; Hiroshi Ito; Toyoaki Murohara; Ken-Ichi Hirata; Koichi Node
    Circulation journal : official journal of the Japanese Circulation Society, 87(11), 1707-1709, Oct. 2023リポジトリ電子ジャーナル
  • Real-world Practical Experience of Angiotensin Receptor-neprilysin Inhibitor in Older Japanese Patients with Chronic Heart Failure.
    Toshinori Komatsu; Masatoshi Minamisawa; Ayako Okada; Hirohiko Motoki; Toshio Kasai; Koichiro Kuwahara; Uichi Ikeda
    JMA journal, 6(4), 489-498, Oct. 2023リポジトリ電子ジャーナル
  • Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
    Yuki Tanaka; Shin Kadota; Jian Zhao; Hideki Kobayashi; Satomi Okano; Masaki Izumi; Yusuke Honda; Hajime Ichimura; Naoko Shiba; Takeshi Uemura; Yuko Wada; Shinichiro Chuma; Tsutomu Nakada; Shugo Tohyama; Keiichi Fukuda; Mitsuhiko Yamada; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba
    Stem cell research & therapy, 14(1), 240-240, Sep. 2023, Refereedリポジトリ電子ジャーナル
  • Clinical utility of urinary mulberry bodies/cells testing in the diagnosis of Fabry disease.
    Katsuya Nakamura; Saki Mukai; Yuka Takezawa; Yuika Natori; Akari Miyazaki; Yuichiro Ide; Mayu Takebuchi; Kana Nanato; Mizuki Katoh; Harue Suzuki; Akiko Sakyu; Tomomi Kojima; Emiko Kise; Hiroaki Hanafusa; Tomoki Kosho; Koichiro Kuwahara; Yoshiki Sekijima
    Molecular genetics and metabolism reports, 36, 100983-100983, Sep. 2023リポジトリ電子ジャーナル
  • The characteristics and outcomes in patients with acute heart failure who used tolvaptan: from KCHF registry.
    Ryusuke Nishikawa; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Neiko Ozasa; Tomohisa Tada; Hiroki Sakamoto; Yuta Seko; Masayuki Shiba; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    ESC heart failure, 10(5), 3141-3151, Sep. 2023, Refereed, Not invitedリポジトリ電子ジャーナル
  • Association between complete revascularization of the coronary artery and clinical outcomes in peripheral artery disease: a sub-analysis of the I-PAD Nagano registry.
    Tamon Kato; Yasushi Ueki; Masatoshi Minamisawa; Takashi Miura; Yushi Oyama; Naoto Hashizume; Daisuke Yokota; Minami Taki; Keisuke Senda; Yoshiteru Okina; Tadamasa Wakabayashi; Koki Fujimori; Kenichi Karube; Takahiro Sakai; Hidetomo Nomi; Hisanori Yui; Yusuke Kanzaki; Keisuke Machida; Shusaku Maruyama; Ayumu Nagae; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Hirohiko Motoki; Koichiro Kuwahara
    Heart and vessels, 38(8), 1001-1008, Aug. 2023リポジトリ電子ジャーナル
  • Symptom-based portopulmonary hypertension screening questionnaire in Japanese patients with chronic liver disease.
    Shun-Ichi Wakabayashi; Satoru Joshita; Kazuhiro Kimura; Hirohiko Motoki; Taiki Okumura; Hiroyuki Kobayashi; Yuki Yamashita; Ayumi Sugiura; Tomoo Yamazaki; Takefumi Kimura; Koichiro Kuwahara; Takeji Umemura
    JGH open : an open access journal of gastroenterology and hepatology, 7(8), 527-536, Aug. 2023, Refereedリポジトリ電子ジャーナル
  • Prognostic Impact of Hyperpolypharmacy Due to Noncardiovascular Medications in Patients After Acute Decompensated Heart Failure - Insights From the Clue of Risk Stratification in the Elderly Patients With Heart Failure (CURE-HF) Registry.
    Masafumi Kanai; Masatoshi Minamisawa; Hirohiko Motoki; Yuta Seko; Kazuhiro Kimura; Takahiro Okano; Yasushi Ueki; Koji Yoshie; Tamon Kato; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Neiko Ozasa; Takao Kato; Koichiro Kuwahara
    Circulation journal : official journal of the Japanese Circulation Society, 88(1), 33-42, Aug. 2023, Refereed, Not invitedリポジトリ電子ジャーナル
  • Utility of a multipurpose catheter for transvenous extraction of old broken leads: A novel technique for fragile leads.
    Ayako Okada; Satoshi Higuchi; Morio Shoda; Hiroaki Tabata; Shohei Kataoka; Wataru Shoin; Hideki Kobayashi; Takahiro Okano; Koji Yoshie; Ken Kato; Tatsuya Saigusa; Soichiro Ebisawa; Hirohiko Motoki; Koichiro Kuwahara
    Heart rhythm, 20(7), 976-981, Jul. 2023リポジトリ電子ジャーナル
  • Natriuretic peptides: role in the diagnosis and management of heart failure: a scientific statement from the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society.
    Hiroyuki Tsutsui; Nancy M Albert; Andrew J S Coats; Stefan D Anker; Antoni Bayes-Genis; Javed Butler; Ovidiu Chioncel; Christopher R Defilippi; Mark H Drazner; G Michael Felker; Gerasimos Filippatos; Mona Fiuzat; Tomomi Ide; James L Januzzi Jr; Koichiro Kinugawa; Koichiro Kuwahara; Yuya Matsue; Robert J Mentz; Marco Metra; Ambarish Pandey; Giuseppe Rosano; Yoshihiko Saito; Yasushi Sakata; Naoki Sato; Petar M Seferovic; John Teerlink; Kazuhiro Yamamoto; Michihiro Yoshimura
    European journal of heart failure, 25(5), 616-631, May 2023リポジトリ電子ジャーナル
  • Natriuretic Peptides: Role in the Diagnosis and Management of Heart Failure: A Scientific Statement From the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society.
    Hiroyuki Tsutsui; Nancy M Albert; Andrew J S Coats; Stefan D Anker; Antoni Bayes-Genis; Javed Butler; Ovidiu Chioncel; Christopher R Defilippi; Mark H Drazner; G Michael Felker; Gerasimos Filippatos; Mona Fiuzat; Tomomi Ide; James L Januzzi Jr; Koichiro Kinugawa; Koichiro Kuwahara; Yuya Matsue; Robert J Mentz; Marco Metra; Ambarish Pandey; Giuseppe Rosano; Yoshihiko Saito; Yasushi Sakata; Naoki Sato; Petar M Seferovic; John Teerlink; Kazuhiro Yamamoto; Michihiro Yoshimura
    Journal of cardiac failure, 29(5), 787-804, May 2023リポジトリ電子ジャーナル
  • Heterogeneity in characteristics and outcomes of patients who met the indications for vericiguat approved by the Japanese agency: from the KCHF registry.
    Masayuki Shiba; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Yugo Yamashita; Moritake Iguchi; Kazuya Nagao; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    Journal of cardiac failure, 29(6), 976-978, Apr. 2023リポジトリ電子ジャーナル
  • Prevention of Contrast-Induced Nephropathy After Emergency Percutaneous Coronary Intervention With a Single Bolus Administration of High-Concentrate Sodium Bicarbonate ― Rationale and Design of a Single-Arm Study Compared With Historical Controls ―
    Takuya Nakamura; Makoto Watanabe; Kazutaka Nogi; Takaaki Kosugi; Yukihiro Hashimoto; Tomoya Ueda; Naofumi Doi; Hiroyuki Kawata; Manabu Horii; Kenichi Ishigami; Tamio Nakajima; Hiroaki Watabe; Daisuke Abe; Koichiro Kuwahara; Yasuo Okumura; Naoki Ozu; Shota Suzuki; Shu Kasama; Yoshihiko Saito
    Circulation Reports, 5(4), 152-156, Apr. 2023, Refereedリポジトリ電子ジャーナル
  • Periprocedural myocardial infarction in patients undergoing percutaneous coronary intervention.
    Yasushi Ueki; Koichiro Kuwahara
    Journal of cardiology, 81(4), 364-372, Apr. 2023リポジトリ電子ジャーナル
  • Tricuspid regurgitation in elderly patients with acute heart failure: insights from the KCHF registry.
    Yuki Obayashi; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yuta Seko; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura
    ESC heart failure, 10(3), 1948-1960, Mar. 2023リポジトリ電子ジャーナル
  • JCS 2023 Guideline on the Diagnosis and Treatment of Myocarditis.
    Toshiyuki Nagai; Takayuki Inomata; Takashi Kohno; Takuma Sato; Atsushi Tada; Toru Kubo; Kazufumi Nakamura; Noriko Oyama-Manabe; Yoshihiko Ikeda; Takeo Fujino; Yasuhide Asaumi; Takahiro Okumura; Toshiyuki Yano; Kazuko Tajiri; Hiroyuki Matsuura; Yuichi Baba; Haruki Sunami; Shingo Tsujinaga; Yasutoshi Ota; Keiko Ohta-Ogo; Yusuke Ishikawa; Hideo Matama; Nobutaka Nagano; Kimi Sato; Kazushi Yasuda; Yasushi Sakata; Koichiro Kuwahara; Tohru Minamino; Minoru Ono; Toshihisa Anzai
    Circulation journal : official journal of the Japanese Circulation Society, 87(5), 674-754, Mar. 2023, Refereedリポジトリ電子ジャーナル
  • A Multicenter Prospective Interventional Trial of Therapeutic Angiogenesis Using Bone Marrow-Derived Mononuclear Cell Implantation for Patients With Critical Limb-Threatening Ischemia Caused by Thromboangiitis Obliterans.
    Ayumu Fujioka; Kenji Yanishi; Arito Yukawa; Kojiro Imai; Isao Yokota; Kei Fujikawa; Ayumu Yamada; Akari Naito; Keisuke Shoji; Hirofumi Kawamata; Yukihito Higashi; Tomoaki Ishigami; Ken-Ichiro Sasaki; Syuhei Tara; Koichiro Kuwahara; Satoshi Teramukai; Satoaki Matoba
    Circulation journal : official journal of the Japanese Circulation Society, 87(9), 1229-1237, Mar. 2023, Refereedリポジトリ電子ジャーナル
  • Association between changes in loop diuretic dose and outcomes in acute heart failure.
    Yuta Seko; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Masayuki Shiba; Erika Yamamoto; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    ESC heart failure, E-pub(3), 1757-1770, Mar. 2023, Refereed, Not invitedリポジトリ電子ジャーナル
  • Rationale and Study design of the GOREISAN for Heart Failure (GOREISAN-HF) trial: A randomized clinical trial.
    Hidenori Yaku; Takao Kato; Takeshi Morimoto; Kazuhisa Kaneda; Ryusuke Nishikawa; Takeshi Kitai; Yasutaka Inuzuka; Yodo Tamaki; Taketoshi Yamazaki; Jun Kitamura; Hirotaka Ezaki; Kazuya Nagao; Hiromi Yamamoto; Akihiro Isotani; Arita Takeshi; Chisato Izumi; Yukihito Sato; Yoshihisa Nakagawa; Satoaki Matoba; Yasushi Sakata; Koichiro Kuwahara; Takeshi Kimura
    American heart journal, 260, 18-25, Feb. 2023, Refereedリポジトリ電子ジャーナル
  • Prognostic value of the severity of clinical congestion in patients hospitalized for decompensated heart failure: Findings from the Japanese KCHF registry.
    Kenji Aida; Kazuya Nagao; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Tsukasa Inada; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura
    Journal of cardiac failure, 29(8), 1150-1162, Jan. 2023リポジトリ電子ジャーナル
  • Weight loss during follow-up in patients with acute heart failure: From the KCHF registry.
    Yuta Seko; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Masayuki Shiba; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Yugo Yamashita; Moritake Iguchi; Kazuya Nagao; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    PloS one, 18(6), e0287637, 2023リポジトリ電子ジャーナル
  • Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration.
    Hideki Kobayashi; Shugo Tohyama; Hideaki Kanazawa; Hajime Ichimura; Shuji Chino; Yuki Tanaka; Yota Suzuki; Jian Zhao; Naoko Shiba; Shin Kadota; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
    Journal of molecular and cellular cardiology, 174, 77-87, Nov. 2022, Refereedリポジトリ電子ジャーナル
  • Association of intravenous heparin administration with in-hospital clinical outcomes among hospitalized patients with acute heart failure.
    Yasuhiro Hamatani; Takao Kato; Takeshi Morimoto; Moritake Iguchi; Hidenori Yaku; Yasutaka Inuzuka; Takeshi Kitai; Kazuya Nagao; Yodo Tamaki; Erika Yamamoto; Neiko Ozasa; Yugo Yamashita; Mitsuru Abe; Yukihito Sato; Koichiro Kuwahara; Masaharu Akao; Takeshi Kimura
    International journal of cardiology, 370, 229-235, Nov. 2022, Refereedリポジトリ電子ジャーナル
  • Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through β-adrenoceptors.
    Sayaka Oda; Kazuhiro Nishiyama; Yuka Furumoto; Yohei Yamaguchi; Akiyuki Nishimura; Xiaokang Tang; Yuri Kato; Takuro Numaga-Tomita; Toshiyuki Kaneko; Supachoke Mangmool; Takuya Kuroda; Reishin Okubo; Makoto Sanbo; Masumi Hirabayashi; Yoji Sato; Yasuaki Nakagawa; Koichiro Kuwahara; Ryu Nagata; Gentaro Iribe; Yasuo Mori; Motohiro Nishida
    Nature communications, 13(1), 6374-6374, Oct. 2022, Refereedリポジトリ電子ジャーナル
  • A comparison between hospital follow-up and collaborative follow-up in patients with acute heart failure.
    Koichi Washida; Takao Kato; Neiko Ozasa; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Yuta Seko; Erika Yamamoto; Yusuke Yoshikawa; Masayuki Shiba; Takeshi Kitai; Yugo Yamashita; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Yuichi Kawase; Yuji Nishimoto; Takashi Kuragaichi; Kozo Hotta; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    ESC heart failure, 10(1), 353-365, Oct. 2022, Refereedリポジトリ電子ジャーナル
  • Prevention of Contrast-Induced Nephropathy After Cardiovascular Catheterization and Intervention With High-Dose Strong Statin Therapy in Japan ― The PREVENT CINC-J Study ―
    Makoto Watanabe; Kazutaka Aonuma; Toyoaki Murohara; Yasuo Okumura; Takeshi Morimoto; Sadanori Okada; Sunao Nakamura; Shiro Uemura; Koichiro Kuwahara; Tadateru Takayama; Naofumi Doi; Tamio Nakajima; Manabu Horii; Kenichi Ishigami; Kazumiki Nomoto; Daisuke Abe; Koji Oiwa; Kentaro Tanaka; Terumasa Koyama; Akira Sato; Tomoya Ueda; Tsunenari Soeda; Yoshihiko Saito
    Circulation Journal, 86(9), 1455-1463, Aug. 2022リポジトリ電子ジャーナル
  • Insomnia in patients with acute heart failure: from the KCHF registry
    Yuta Seko; Erika Yamamoto; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Masayuki Shiba; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    ESC Heart Failure, 9(5), 2988-2996, Jun. 2022リポジトリ電子ジャーナル
  • Public assistance in patients with acute heart failure: a report from the KCHF registry
    Yuji Nishimoto; Takao Kato; Takeshi Morimoto; Ryoji Taniguchi; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Koichiro Kuwahara; Neiko Ozasa; Yukihito Sato; Takeshi Kimura
    ESC Heart Failure, 9(3), 1920-1930, Jun. 2022, Refereedリポジトリ電子ジャーナル
  • Infective endocarditis caused by Streptococcus pneumoniae from sinusitis: A case report.
    Ken Yamazaki; Takashi Miura; Daisuke Sunohara; Toshinori Komatsu; Tomoaki Mochidome; Toshio Kasai; Uichi Ikeda; Koichiro Kuwahara
    Journal of cardiology cases, 25(5), 279-281, May 2022リポジトリ電子ジャーナル
  • 拡張型心筋症モデルマウスを用いた心腎連関の機序解明
    石村 拓也; 石井 輝; 山田 博之; 中川 靖章; 大野 祥子; 生島 昭恵; 杉岡 清香; 半田 貴也; 桑原 宏一郎; 柳田 素子; 横井 秀基
    日本腎臓学会誌, 64(3), 318-318, May 2022
  • Gender difference in heart failure with preserved ejection fraction: clinical profiles, examinations, and prognosis.
    Takahiro Sakai; Hirohiko Motoki; Sho Suzuki; Aya Fuchida; Takahiro Takeuchi; Kyuhachi Otagiri; Masafumi Kanai; Kazuhiro Kimura; Masatoshi Minamisawa; Koji Yoshie; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Hiroshi Kitabayashi; Koichiro Kuwahara
    Heart and vessels, 37(10), 1710-1718, Apr. 2022リポジトリ電子ジャーナル
  • Intensive exercise therapy for restenosis after superficial femoral artery stenting: the REASON randomized clinical trial.
    Tamon Kato; Takashi Miura; Shuhei Yamamoto; Yusuke Miyashita; Naoto Hashizume; Kyoko Shoin; Shinya Sasaki; Yusuke Kanzaki; Hisanori Yui; Shusaku Maruyama; Ayumu Nagae; Takahiro Sakai; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Hirohiko Motoki; Uichi Ikeda; Koichiro Kuwahara
    Heart and vessels, 37(9), 1596-1603, Apr. 2022, Refereedリポジトリ電子ジャーナル
  • Left atrial reverse remodeling improves risk stratification in patients with heart failure with recovered ejection fraction.
    Masayuki Shiba; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Yugo Yamashita; Moritake Iguchi; Kazuya Nagao; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    Scientific reports, 12(1), 4473-4473, Mar. 2022リポジトリ電子ジャーナル
  • Starting Neurohormonal Antagonists in Patients With Acute Heart Failure With Mid-Range and Preserved Ejection Fraction.
    Yuta Seko; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Masayuki Shiba; Erika Yamamoto; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    Circulation journal : official journal of the Japanese Circulation Society, 86(10), 1547-1558, Feb. 2022, Refereedリポジトリ電子ジャーナル
  • 【循環器疾患におけるレニン・アンジオテンシン・アルドステロン(RAA)系の新たな展望】心血管病におけるRAA系の意識を再考する
    桑原 宏一郎; 斎藤 能彦; 吉村 道博; 下澤 達雄
    Cardiac Practice, 32(2), 135-141, Feb. 2022リポジトリ
  • Current use of inotropes according to initial blood pressure and peripheral perfusion in the treatment of congestive heart failure: findings from a multicentre observational study.
    Kazuya Nagao; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Tsukasa Inada; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura
    BMJ open, 12(1), e053254, Jan. 2022リポジトリ電子ジャーナル
  • Polypharmacy and Clinical Outcomes in Hospitalized Patients With Acute Decompensated Heart Failure.
    Neiko Ozasa; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Erika Yamamoto; Yasutaka Inuzuka; Yodo Tamaki; Takeshi Kitai; Koichi Washida; Yuta Seko; Yusuke Yoshikawa; Yukihito Sato; Hirohiko Motoki; Koichiro Kuwahara; Takeshi Kimura
    The Journal of cardiovascular nursing, Jan. 2022リポジトリ電子ジャーナル
  • Effects of cardiac surgical support on long-term outcomes of emergent or complex percutaneous coronary intervention cases: a sub-analysis of the SHINANO 5-year registry
    Chie Nakamura; Soichiro Ebisawa; Takashi Miura; Hidetomo Nomi; Yusuke Kanzaki; Hisanori Yui; Shusaku Maruyama; Ayumu Nagae; Yasushi Ueki; Takahiro Sakai; Tamon Kato; Tatsuya Saigusa; Ayako Okada; Hirohiko Motoki; Koichiro Kuwahara
    HEART AND VESSELS, 37(7), 1106-1114, Jan. 2022WebofScienceリポジトリ電子ジャーナル
  • Comparison of prognostic impact of anticoagulants in heart failure patients with atrial fibrillation and renal dysfunction: direct oral anticoagulants versus vitamin K antagonists
    Takahiro Sakai; Hirohiko Motoki; Aya Fuchida; Takahiro Takeuchi; Kyuhachi Otagiri; Masafumi Kanai; Kazuhiro Kimura; Masatoshi Minamisawa; Koji Yoshie; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Hiroshi Kitabayashi; Koichiro Kuwahara
    HEART AND VESSELS, Jan. 2022WebofScienceリポジトリ電子ジャーナル
  • 神経体液性因子抑制の新しい展開 : ARNIおよび新世代MRA
    桑原 宏一郎
    Heart View, 26(1), 68-74, Jan. 2022
  • Appetite loss at discharge from acute decompensated heart failure: Observation from KCHF registry.
    Erika Yamamoto; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mitsunori Kawato; Yuta Seko; Masayuki Shiba; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    PloS one, 17(5), e0267327, 2022リポジトリ電子ジャーナル
  • Changes in BNP levels from discharge to 6-month visit predict subsequent outcomes in patients with acute heart failure.
    Masayuki Shiba; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Yuta Seko; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Yugo Yamashita; Moritake Iguchi; Kazuya Nagao; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Yasuaki Nakagawa; Koichiro Kuwahara; Takeshi Kimura
    PloS one, 17(1), e0263165, 2022リポジトリ電子ジャーナル
  • Gigantic Pacemaker Pocket Abscess Infected by Staphylococcus epidermidis
    Okano T, Okada A, Shoda M, Kuwahara K
    Intern Med, 61(4), 593-594, 2022
  • Successful endovascular treatment with a stent graft for chronic deep vein thrombosis with multiple arteriovenous fstulas: a case report
    Kato T, Fuke M, Nagai F, Nomi H, Kanzaki Y, Yui H, Maruyama S, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K
    J Med Case Rep, 16(1), 257, 2022
  • Cilostazol effectiveness in reducing drugcoated stent restenosis in the superficial femoral artery: The ZERO study
    Miura T, Miyashita Y, Hozawa K, Doijiri T, Kato T, Hayakawa N, Hashizume N, Nakano M, Ikeda U, Kuwahara K, on behalf of the ZERO Investigators
    PLOS ONE, 17(7), e0270992, 2022
  • Usefulness of the controlled-rotation dilator sheath “Evolution RL” for extraction of old leads in two Japanese centers – An experience in use
    Tabata H, Okada A, Kobayashi H, Shoin W, Okano T, Higuchi S, Yagishita D, Ebisawa S, Motoki H, Shoda M, Kuwahara K
    J Cardiol, 80(4), 339-343, 2022
  • The Impact of Hyperuricemia on Patients With Low Body Mass Index After Endovascular Treatments: Data From the I-PAD Registry
    Nagae A, Ebisawa S, Saigusa T, Nishikawa K, Fujimori K, Yui H, Maruyama S, Nakamura C, Kashiwagi D, Kobayashi H, Sakai T, Senda K, Kato T, Miura T, Okada A, Motoki H, Kuwahara K
    Angiology, 73(8), 753-763, 2022
  • Impact of Frailty and Age on Clinical Outcomes in Patients Who Underwent Endovascular Therapy
    Nishikawa K, Ebisawa S, Miura T, Kato T, Kanzaki Y, Abe N, Yokota D, Yanagisawa T, Senda K, Wakabayashi T, Oyama Y, Karube K, Itagaki T, Yui H, Maruyama S, Nagae A, Sakai T, Okina Y, Nakazawa S, Tsukada S, Saigusa T, Okada A, Motoki H, Kagoshima M, Kuwahara K
    J Endovasc Ther, 29(6), 845-854, 2022
  • NRSF-GNAO1 Pathway Contributes to the Regulation of Cardiac Ca2+ Homeostasis
    Inazumi H, Kuwahara K, Nakagawa Y, Kuwabara Y, Numaga-Tomita T, Kashihara T, Nakada T, Kurebayashi N, Oya M, Nonaka M, Sugihara M, Kinoshita H, Moriuchi K, Yanagisawa H, Nishikimi T, Motoki H, Yamada M, Morimoto S, Otsu K, Mortensen RM, Nakao K, Kimura T
    Circ Res, 130(2), 234-248, 2022
  • Coronary angiography in patients with acute heart failure: from the KCHF registry
    Seko Y, Kishimori T, Kato T, Morimoto T, Yaku H, Inuzuka Y, Tamaki Y, Ozasa N, Shiba M, Yamamoto E, Yoshikawa Y, Yamashita Y, Kitai T, Taniguchi R, Iguchi M, Nagao K, Kawai T, Komasa A, Nishikawa R, Kawase Y, Morinaga T, Toyofuku M, Furukawa Y, Ando K, Kadota K, Sato Y, Kuwahara K, Kimura T; KCHF Study Investigators
    ESC Heart Fail, 9(1), 531-544, 2022
  • NRSF/REST-Mediated Epigenomic Regulation in the Heart: Transcriptional Control of Natriuretic Peptides and Beyond
    Inazumi H, Kuwahara K
    Biology, 11(8), 1197, 2022
  • Therapeutic angiogenesis for patients with no-option critical limb ischemia by adipose-derived regenerative cells: TACT-ADRC multicenter trial
    Shimizu Y, Kondo K, Hayashida R, Sasaki KI, Ohtsuka M, Fukumoto Y, Takashima S, Inoue O, Usui S, Takamura M, Sakuma M, Inoue T, Nagata T, Akashi YJ, Yamada Y, Kato T, Kuwahara K, Tateno K, Kobayashi Y, Shibata R, Murohara T; TACT-ADRC multicenter trial Group
    Angiogenesis, 25(4), 535-546, 2022
  • Status of adult outpatients with congenital heart disease in Japan: The Japanese Network of Cardiovascular Departments for Adult Congenital Heart Disease Registry
    Yao A, Inuzuka R, Mizuno A, Iwano H, Tatebe S, Tsukamoto Y, Sakamoto I, Watanabe H, Fukuda N, Takechi F, Adachi S, Akazawa Y, Kuwahara K, Dohi K, Ishizu T, Miyake M, Koitabashi N, Hasegawa-Tamba S, Sato S, Fujii T, Ehara E, Minamino T, Yamada H, Yamashita E, Kawamatsu N, Masuda K, Soma K, Shiraishi I, Nagai R, Niwa K; JNCVD-ACHD investigators
    J Cardiol, 80(6), 525-531, 2022
  • NRSF-GNAO1 Pathway Contributes to the Regulation of Cardiac Ca 2+ Homeostasis
    Hideaki Inazumi; Koichiro Kuwahara; Yasuaki Nakagawa; Yoshihiro Kuwabara; Takuro Numaga-Tomita; Toshihide Kashihara; Tsutomu Nakada; Nagomi Kurebayashi; Miku Oya; Miki Nonaka; Masami Sugihara; Hideyuki Kinoshita; Kenji Moriuchi; Hiromu Yanagisawa; Toshio Nishikimi; Hirohiko Motoki; Mitsuhiko Yamada; Sachio Morimoto; Kinya Otsu; Richard M Mortensen; Kazuwa Nakao; Takeshi Kimura
    Circulation Research, Dec. 2021リポジトリ電子ジャーナル
  • Body composition and mortality in patients undergoing endovascular treatment for peripheral artery disease
    Tadashi Itagaki; Soichiro Ebisawa; Kyuhachi Otagiri; Tamon Kato; Takashi Miura; Yusuke Kanzaki; Naoyuki Abe; Daisuke Yokota; Takashi Yanagisawa; Keisuke Senda; Yoshiteru Okina; Tadamasa Wakabayashi; Yushi Oyama; Kenichi Karube; Keisuke Machida; Takahiro Takeuchi; Tatsuya Saigusa; Hirohiko Motoki; Hiroshi Kitabayashi; Koichiro Kuwahara
    HEART AND VESSELS, 36(12), 1830-1840, Dec. 2021WebofScienceリポジトリ電子ジャーナル
  • Impact of Frailty and Age on Clinical Outcomes in Patients Who Underwent Endovascular Therapy
    Ken Nishikawa; Soichiro Ebisawa; Takashi Miura; Tamon Kato; Kanzaki Yusuke; Naoyuki Abe; Daisuke Yokota; Takashi Yanagisawa; Keisuke Senda; Tadamasa Wakabayashi; Yushi Oyama; Kenichi Karube; Tadashi Itagaki; Hisanori Yui; Shusaku Maruyama; Ayumu Nagae; Takahiro Sakai; Yoshiteru Okina; Shun Nakazawa; Shunichi Tsukada; Tatsuya Saigusa; Ayako Okada; Hirohiko Motoki; Mitsuru Kagoshima; Koichiro Kuwahara
    JOURNAL OF ENDOVASCULAR THERAPY, 29(6), 845-854, Dec. 2021WebofScienceリポジトリ電子ジャーナル
  • Ischemic Stroke in Acute Decompensated Heart Failure: From the KCHF Registry
    Moritake Iguchi; Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Yasuhiro Hamatani; Yugo Yamashita; Nobutoyo Masunaga; Hisashi Ogawa; Mitsuru Ishii; Yoshimori An; Ryoji Taniguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mitsunori Kawato; Yuta Seko; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Mitsuru Abe; Masaharu Akao; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(21), Nov. 2021WebofScienceリポジトリ電子ジャーナル
  • The natriuretic peptide system in heart failure: Diagnostic and therapeutic implications
    Koichiro Kuwahara
    PHARMACOLOGY & THERAPEUTICS, 227, Nov. 2021WebofScienceリポジトリ電子ジャーナル
  • Newly Diagnosed Infection After Admission for Acute Heart Failure: From the KCHF Registry
    Yuta Seko; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Masayuki Shiba; Erika Yamamoto; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Toshikazu Jinnai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(22), e023256, Nov. 2021WebofScienceリポジトリ電子ジャーナル
  • Coronary angiography in patients with acute heart failure: from the KCHF registry
    Yuta Seko; Takefumi Kishimori; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Masayuki Shiba; Erika Yamamoto; Yusuke Yoshikawa; Yugo Yamashita; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yutaka Furukawa; Kenji Ando; Kazushige Kadota; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    ESC HEART FAILURE, Nov. 2021WebofScienceリポジトリ電子ジャーナル
  • Relationship between the flood disaster caused by the Reiwa first year east Japan typhoon and cardiovascular and cerebrovascular events in Nagano City: The SAVE trial
    Daisuke Sunohara; Takashi Miura; Toshinori Komatsu; Naoto Hashizume; Tomoyasu Momose; Tsunesuke Kono; Hirohiko Motoki; Tomoaki Mochidome; Toshio Kasai; Koichiro Kuwahara; Uichi Ikeda
    JOURNAL OF CARDIOLOGY, 78(5), 447-455, Nov. 2021WebofScienceリポジトリ電子ジャーナル
  • Successful bailout of stent graft stuck in stent occlusion lesion
    Tamon Kato; Ayumu Nagae; Takahiro Sakai; Tatsuya Saigusa; Soichiro Ebisawa; Koichiro Kuwahara
    CARDIOVASCULAR INTERVENTION AND THERAPEUTICS, 36(4), 535-536, Oct. 2021WebofScienceリポジトリ電子ジャーナル
  • Prognostic ability of mid-term worsening renal function after percutaneous coronary intervention: findings from the SHINANO registry
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  • 第三世代ミネラルコルチコイド受容体拮抗薬(MRA) (特集 新規心不全治療薬の使い方)
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  • Protocol: Prospective observational study investigating the prevalence and clinical outcome of portopulmonary hypertension in Japanese patients with chronic liver disease
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    PLOS ONE, 16(4), Apr. 2021WebofScienceリポジトリ電子ジャーナル
  • 心筋胎児型遺伝子発現調節経路 (特集 ナトリウム利尿ペプチドに関する話題)
    桑原 宏一郎;クワハラ コウイチロウ
    循環器内科 = Cardioangiology / 循環器内科編集委員会 編, 89(4), 375-378, Apr. 2021
  • A case of transient ventricular pre-excitation associated with takotsubo cardiomyopathy
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    JOURNAL OF ELECTROCARDIOLOGY, 65, 73-75, Mar. 2021WebofScienceリポジトリ電子ジャーナル
  • Searching for the Frequency of Cardiac Transthyretin Amyloidosis among Elderly Heart Failure Patients Noninvasively Using 99mTc-labeled Pyrophosphate Scintigraphy
    Miura, Takashi; Okina, Yoshiteru ; Mochidome, Tomoaki; Kobayashi, Takahiro; Kasai, Toshio; Ikeda, Uichi; Ezawa, Naoki; Sekijima, Yoshiki; Kuwahara, Koichiro
    The Shinshu Medical Journal, 69(1), 37-44, 10 Feb. 2021リポジトリ電子ジャーナル
  • Prognostic value of reduction in left atrial size during a follow-up of heart failure: an observational study.
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  • Granulocyte colony stimulating factor-associated aortitis evaluated via multiple imagingmodalities including vascular echography: a case report
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  • Prognostic usefulness of residual SYNTAX score combined with clinical factors for patients with acute coronary syndrome who underwent percutaneous coronary intervention from the SHINANO Registry
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  • KCHF Study InvestigatorsSex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry (vol 7, pg 2485, 2020)
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  • Leadless cardiac pacemaker implantations after infected pacemaker system removals in octogenarians
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  • Association of the Prognosis of Ankle-brachial Index Improvement One Year Following Endovascular Therapy in Patients with Peripheral Artery Disease: Data from the I-PAD NAGANO Registry
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  • Influence of Worsening Heart Failure During Hospitalization on the Prognosis in Patients with Acute Decompensated Heart Failure
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  • Association of an increase in serum albumin levels with positive 1-year outcomes in acute decompensated heart failure: A cohort study
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  • Sex differences in patients with acute decompensated heart failure in Japan: observation from the KCHF registry
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  • Prognostic significance of resting heart rate in atrial fibrillation patients with heart failure with reduced ejection fraction
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  • Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
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    Scientific reports, 10(1), 11883-11883, Jul. 2020WebofScienceリポジトリ電子ジャーナル
  • 超高齢社会を迎えた心不全診療のあり方 高齢の急性心不全患者における機能低下、繰り返す入退院、および治療と長期予後との関連(Association of Functional Decline, Repeated Hospitalization, and Treatment with Long-term Prognosis in Older Adults with Acute Heart Failure)
    夜久 英憲; 加藤 貴雄; 森本 剛; 犬塚 康孝; 田巻 庸道; 小笹 寧子; 山本 絵里香; 佐藤 幸人; 桑原 宏一郎; 木村 剛
    日本循環器学会学術集会抄録集, 84回, シンポジウム5-3, Jul. 2020
  • Impact of Ambulation Status in Patients with End-stage Renal Disease on Hemodialysis due to Diabetic Nephropathy : The PREDICT Study
    Kato T, Miyashita Y, Sone H, Mizukami T, Kanno Y, Oguchi T, Yokota D, Shiotsuki N, Mizukami E, Terashima M, Aruga M, Yui H, Maruyama S, Kobayashi H, Kashiwagi D, Nagae A, Sakai T, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K
    The Shinshu Medical Journal, 68(3), 131-138, 10 Jun. 2020リポジトリ電子ジャーナル
  • Prognostic Impact of Cardio-renal-anemia Syndrome in Patients at Risk for Heart Failure from the IMPACT-ABI study
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    The Shinshu Medical Journal, 68(3), 139-147, 10 Jun. 2020リポジトリ電子ジャーナル
  • Rationale and design of the EMPYREAN study.
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    ESC heart failure, 7(5), 3134-3141, Jun. 2020, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Sodium-Glucose Cotransporter-2 inhibitors are potential therapeutic agents for treatment of non-diabetic heart failure patients.
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  • Successful hot balloon ablation for focal atrial tachycardia derived from the left superior pulmonary vein antrum
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  • MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice
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  • Establishment of optimal exercise therapy using near-infrared spectroscopy monitoring of tissue muscle oxygenation after therapeutic angiogenesis for patients with critical limb ischemia: A multicenter, randomized, controlled trial
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  • A Predictive Model for 6-Month Mortality in Elderly Patients with Heart Failure
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    INTERNATIONAL HEART JOURNAL, 61(2), 325-331, Mar. 2020WebofScienceリポジトリ電子ジャーナル
  • Association with Controlling Nutritional Status (CONUT) Score and In-hospital Mortality and Infection in Acute Heart Failure
    Takao Kato; Hidenori Yaku; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Neiko Ozasa; Takeshi Kimura
    SCIENTIFIC REPORTS, 10(1), Feb. 2020WebofScienceリポジトリ電子ジャーナル
  • Risk factors and clinical outcomes of functional decline during hospitalisation in very old patients with acute decompensated heart failure: an observational study
    Hidenori Yaku; Takao Kato; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Masashi Kato; Tomoyuki Ikeda; Yutaka Furukawa; Yoshihisa Nakagawa; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura
    BMJ OPEN, 10(2), Feb. 2020WebofScienceリポジトリ電子ジャーナル
  • A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis
    Endo, Jin; Sano, Motoaki; Izumiya, Yasuhiro; Tsujita, Kenichi; Nakamura, Kazufumi; Tahara, Nobuhiro; Kuwahara, Koichiro; Inomata, Takayuki; Ueda, Mitsuharu; Sekijima, Yoshiki; Ando, Yukio; Tsutsui, Hiroyuki; Isobe, Mitsuaki; Fukuda, Keiichi;
    CIRCULATION JOURNAL, 84(1), 15-17, Jan. 2020WebofScience電子ジャーナル
  • C-reactive protein at discharge and 1-year mortality in hospitalised patients with acute decompensated heart failure: an observational study
    Yuji Nishimoto; Takao Kato; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Yuta Seko; Moriaki Inoko; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Koichiro Kuwahara; Neiko Ozasa; Yukihito Sato; Takeshi Kimura
    BMJ OPEN, 10(12), 2020WebofScienceリポジトリ電子ジャーナル
  • Increased Ga(o)Expression Regulated by NRSF Plays a Key Role in the Development of Heart Failure Through the Impairment of Ca2+ Homeostasis
    Inazumi, Hideaki; Nakagawa, Yasuaki; Moriuchi, Kenji; Kuwahara, Koichiro;
    Circulation Research, 127, 2020WebofScience電子ジャーナル
  • A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis.
    Jin Endo; Motoaki Sano; Yasuhiro Izumiya; Kenichi Tsujita; Kazufumi Nakamura; Nobuhiro Tahara; Koichiro Kuwahara; Takayuki Inomata; Mitsuharu Ueda; Yoshiki Sekijima; Yukio Ando; Hiroyuki Tsutsui; Mitsuaki Isobe; Keiichi Fukuda
    Circulation journal : official journal of the Japanese Circulation Society, 84(1), 15-17, Dec. 2019, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Association of Previous Hospitalization for Heart Failure With Increased Mortality in Patients Hospitalized for Acute Decompensated Heart Failure
    Kanae Su; Takao Kato; Mamoru Toyofuku; Takeshi Morimoto; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Erika Yamamoto; Yusuke Yoshikawa; Yasuyo Motohashi; Hiroki Watanabe; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Toshikazu Jinnai; Mitsunori Kawato; Yukihito Sato; Koichiro Kuwahara; Takashi Tamura; Takeshi Kimura
    Circulation Reports, 1(11), 517-524, Nov. 2019, Refereed, Not invitedリポジトリ電子ジャーナル
  • Impact of inpatient cardiac rehabilitation on Barthel Index score and prognosis in patients with acute decompensated heart failure
    Hirohiko Motoki; Musashi Nishimura; Masafumi Kanai; Kazuhiro Kimura; Masatoshi Minamisawa; Shuhei Yamamoto; Tatsuya Saigusa; Soichiro Ebisawa; Ayako Okada; Koichiro Kuwahara
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 293, 125-130, Oct. 2019WebofScienceリポジトリ電子ジャーナル
  • Prognostic significance of high-sensitivity cardiac troponin in patients with heart failure with preserved ejection fraction
    Sho Suzuki; Hirohiko Motoki; Masatoshi Minamisawa; Yukari Okuma; Wataru Shoin; Takahiro Okano; Kazuhiro Kimura; Soichiro Ebisawa; Ayako Okada; Koichiro Kuwahara
    HEART AND VESSELS, 34(10), 1650-1656, Oct. 2019WebofScienceリポジトリ電子ジャーナル
  • Association between reactive hyperemia peripheral arterial tonometry index and atrial fibrillation recurrence after catheter ablation
    Hideki Kobayashi; Ayako Okada; Hiroaki Tabata; Wataru Shoin; Takahiro Okano; Koji Yoshie; Yasutaka Oguchi; Ken Kato; Morio Shoda; Koichiro Kuwahara
    IJC HEART & VASCULATURE, 24, Sep. 2019WebofScienceリポジトリ電子ジャーナル
  • Epicardial Stone - Unfamiliar Calcified Mass at the Site of Left Ventricular Old Myocardial Infarction -
    Hiroaki Tabata; Hirohiko Motoki; Takahiro Sakai; Ayako Okada; Koichiro Kuwahara
    CIRCULATION JOURNAL, 83(9), 1969-1969, Sep. 2019WebofScienceリポジトリ電子ジャーナル
  • MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages.
    Jianbo An; Taeko K Naruse; Kunihiko Hinohara; Yurie Soejima; Motoji Sawabe; Yasuaki Nakagawa; Koichiro Kuwahara; Akinori Kimura
    Journal of molecular and cellular cardiology, 133, 26-35, Aug. 2019, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia.
    Kensuke Oshita; Yuko Kozasa; Yasuaki Nakagawa; Yoshihiro Kuwabara; Koichiro Kuwahara; Taku Nakagawa; Noriyuki Nakashima; Teruyuki Hiraki; Makoto Takano
    The journal of physiological sciences : JPS, 69(4), 653-660, Jul. 2019, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Ankle-Brachial Index as a Prognostic Indicator in Patients with Atrial Fibrillation -A Subanalysis of the IMPACT-ABI Study
    Oguchi Y, Saigusa T, Ebisawa S, Okada A, Motoki H, Kuwahara K
    The Shinshu Medical Journal, 67(3), 197-204, 10 Jun. 2019リポジトリ電子ジャーナル
  • Role of echocardiography in assessing cardiac amyloidoses: a systematic review
    Jun Koyama; Masatoshi Minamisawa; Yoshiki Sekijima; Koichiro Kuwahara; Tsutomu Katsuyama; Kazutoshi Maruyama
    JOURNAL OF ECHOCARDIOGRAPHY, 17(2), 64-75, Jun. 2019WebofScienceリポジトリ電子ジャーナル
  • Association of Mineralocorticoid Receptor Antagonist Use With All-Cause Mortality and Hospital Readmission in Older Adults With Acute Decompensated Heart Failure
    Hidenori Yaku; Takao Kato; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Neiko Ozasa; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Mamoru Toyofuku; Yuta Seko; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takeshi Kimura; Tetsuo Shioi; Yugo Yamashita; Masaharu Akao; Shinji Miki; Tsuneaki Kawashima; Takafumi Yagi; Takashi Konishi; Shigeru Ikeguchi; Yoshihiro Himura; Tsukasa Inada; Kenichi Sasaki; Moriaki Inoko; Tomoki Sasa; Mitsuo Matsuda; Katsuhisa Ishii; Yoshiki Takatsu; Ryousuke Murai; Mitsunori Kawato; Yasuyo Motohashi; Kanae Su; Takashi Tamura; Reiko Hozo; Hiroki Sakamoto; Keiichiro Iwasaki; Yohei Kobayashi; Kenji Ando
    JAMA NETWORK OPEN, 2(6), Jun. 2019WebofScienceリポジトリ電子ジャーナル
  • Utility of copeptin for predicting long-term clinical outcomes in patients with heart failure
    Yusuke Yoshikawa; Hiroki Shiomi; Koichiro Kuwahara; Naoya Sowa; Hidenori Yaku; Yugo Yamashita; Junichi Tazaki; Masao Imai; Takao Kato; Naritatsu Saito; Satoshi Shizuta; Koh Ono; Takeshi Kimura
    Journal of Cardiology, 73(5), 379-385, May 2019WebofScienceリポジトリ電子ジャーナル
  • 抑制性G蛋白サブユニットGαoの発現亢進はCa2+handlingの異常を介して心不全進展にかかわる
    稲住 英明; 桑原 宏一郎; 桑原 佳宏; 中川 靖章; 木下 秀之; 錦見 俊雄; 呉林 なごみ; 山田 充彦; 柏原 俊英; 中尾 一和; 木村 剛
    日本臨床分子医学会学術総会プログラム・抄録集, 56回, 47-47, Apr. 2019
  • Comparison of leg loader and treadmill exercise for evaluating patients with peripheral artery disease
    Yasushi Ueki; Takashi Miura; Tomoaki Mochidome; Keisuke Senda; Soichiro Ebisawa; Tatsuya Saigusa; Hirohiko Motoki; Ayako Okada; Jun Koyama; Koichiro Kuwahara
    HEART AND VESSELS, 34(4), 590-596, Apr. 2019WebofScienceリポジトリ電子ジャーナル
  • Single-center experience with percutaneous lead extraction of cardiac implantable electric devices (vol 71, pg 192, 2018)
    Ayako Okada; Morio Shoda; Hiroaki Tabata; Wataru Shoin; Hideki Kobayashi; Takahiro Okano; Koji Yoshie; Yasutaka Oguchi; Takahiro Takeuchi; Ken Kato; Koichiro Kuwahara
    JOURNAL OF CARDIOLOGY, 73(3-4), 262-262, Mar. 2019WebofScienceリポジトリ電子ジャーナル
  • Impact of Therapeutic Angiogenesis Using Autologous Bone Marrow-Derived Mononuclear Cells Implantation in Critical Limb Ischemia With Scleroderma - Subanalysis of the Long-Term Clinical Outcomes Survey -
    Shoji, Keisuke; Yanishi, Kenji; Yoshimi, Ryusuke; Hamada, Naoki; Kondo, Kazuhisa; Fujimoto, Kazuteru; Nakajima, Hideaki; Kuwahara, Koichiro; Higashi, Yukihito; Fukumoto, Yoshihiro; Murohara, Toyoaki; Matoba, Satoaki; Hayashida, Ryo; Shibata, Rei; Murotani, Kenta; Ando, Masahiko; Mizuno, Masaaki; Fujiwara, Tadami; Fujimoto, Kazuteru; Kato, Tamon; Kajikawa, Masato; Ootsuka, Masanori; Sasaki, Kenichiro; Saito, Yoshihiko; Fukumoto, Shinya
    CIRCULATION JOURNAL, 83(3), 662-671, Mar. 2019, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Establishment of a Healthcare System for Patients With Adult Congenital Heart Disease in Collaboration With Children's Hospital - The Nagano Model -
    Hirohiko Motoki; Satoshi Yasukochi; Kiyohiro Takigiku; Kohta Takei; Toru Okamura; Kazuhiro Kimura; Masatoshi Minamisawa; Ayako Okada; Tatsuya Saigusa; Soichiro Ebisawa; Tatsuichiro Seto; Morio Shoda; Kenji Okada; Koichiro Kuwahara
    CIRCULATION JOURNAL, 83(2), 424-431, Feb. 2019WebofScienceリポジトリ電子ジャーナル
  • Atrial and brain natriuretic peptides: Hormones secreted from the heart
    Nakagawa Y, Nishikimi T, Kuwahara K
    PEPTIDES, 111, 18-25, 2019
  • A case of thrombolytic therapy with recombinant tissue plasminogen activator for mechanical valve thrombosis at 9 weeks of pregnancy in a Japanese woman
    Komatsu T, Motoki H, Kimura K, Saigusa T, Ebisawa S, Yokokawa Y, Ando H, Ichino T, Kuwahara K.
    J Cardiol Cases, 19(1), 15-18, 2019
  • Wire perforation causing cardiopulmonary arrest during radiofrequency hot balloon ablation for pulmonary vein isolation
    Okano T, Okada A, Tabata H, Kobayashi H, Shoin W, Yoshie K, Oguchi Y, Shoda M, Kuwahara K
    J Cardiol Cases, 19(5), 169-172, 2019
  • Successful inferior vena cava filter removal using pacemaker lead extraction methods
    Itagaki T, Okada A, Tabata H, Shoin W, Kobayashi H, Okano T, Oguchi Y, Mochidome T, Saigusa T, Ebisawa S, Motoki H, Shoda M, Kuwahara K
    J Cardiol Cases, 19(4), 129-132, 2019
  • Biopsy detection and clinical management of acute lymphocytic myocarditis in pregnancy
    Sunohara D, Motoki H, Saigusa T, Ebisawa S, Okada A, Ando H, Sato M, Kuwahara K
    J Cardiol Cases, 20(5), 164-167, 2019
  • Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence
    Akiyuki Nishimura; Tsukasa Shimauchi; Tomohiro Tanaka; Kakeru Shimoda; Takashi Toyama; Naoyuki Kitajima; Tatsuya Ishikawa; Naoya Shindo; Takuro Numaga-Tomita; Satoshi Yasuda; Yoji Sato; Koichiro Kuwahara; Yoshito Kumagai; Takaaki Akaike; Tomomi Ide; Akio Ojida; Yasuo Mori; Motohiro Nishida
    SCIENCE SIGNALING, 11(556), eaat5185, Nov. 2018WebofScienceリポジトリ電子ジャーナル
  • Demographics, Management, and In-Hospital Outcome of Hospitalized Acute Heart Failure Syndrome Patients in Contemporary Real Clinical Practice in Japan ― Observations From the Prospective, Multicenter Kyoto Congestive Heart Failure (KCHF) Registry ―
    Hidenori Yaku; Neiko Ozasa; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Takeshi Kitai; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Kanae Su; Mitsunori Kawato; Kenichi Sasaki; Mamoru Toyofuku; Yutaka Furukawa; Yoshihisa Nakagawa; Kenji Ando; Kazushige Kadota; Satoshi Shizuta; Koh Ono; Yukihito Sato; Koichiro Kuwahara; Takao Kato; Takeshi Kimura
    Circulation Journal, 82(11), 2811-2819, Oct. 2018WebofScienceリポジトリ電子ジャーナル
  • T-wave alternans in a case with systemic lupus erythematosus-related myocarditis.
    Mikiko Harada; Hirohiko Motoki; Yuichiro Kashima; Chie Nakamura; Naoto Hashizume; Dai Kishida; Hiroshi Imamura; Koichiro Kuwahara
    Journal of cardiology cases, 18(4), 119-122, Oct. 2018リポジトリ電子ジャーナル
  • Cutting Edge of Brain Natriuretic Peptide (BNP) Research - The Diversity of BNP Immunoreactivity and Its Clinical Relevance.
    Koichiro Kuwahara; Yasuaki Nakagawa; Toshio Nishikimi
    Circulation journal : official journal of the Japanese Circulation Society, 82(10), 2455-2461, Sep. 2018, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Predictive Value of Underweight Status for Patients With Peripheral Artery Disease With Claudication
    Keisuke Senda; Takashi Miura; Masatoshi Minamisawa; Yasushi Ueki; Tomoaki Mochidome; Hidetomo Nomi; Wataru Shoin; Satoko Higuchi; Yasutaka Oguchi; Hitoshi Nishimura; Tatsuya Saigusa; Soichiro Ebisawa; Hirohiko Motoki; Atsushi Izawa; Jun Koyama; Uichi Ikeda; Koichiro Kuwahara
    ANGIOLOGY, 69(6), 513-522, Jul. 2018WebofScienceリポジトリ電子ジャーナル
  • Geriatric Nutritional Risk Index Predicts Cardiovascular Events in Patients at Risk for Heart Failure
    Masatoshi Minamisawa; Takashi Miura; Hirohiko Motoki; Yasushi Ueki; Hitoshi Nishimura; Kunihiko Shimizu; Wataru Shoin; Mikiko Harada; Tomoaki Mochidome; Keisuke Senda; Koji Yoshie; Yasutaka Oguchi; Naoto Hashizume; Naoyuki Abe; Tatsuya Saigusa; Soichiro Ebisawa; Atsushi Izawa; Jun Koyama; Uichi Ikeda; Koichiro Kuwahara
    CIRCULATION JOURNAL, 82(6), 1614-+, Jun. 2018WebofScienceリポジトリ電子ジャーナル
  • Duration of myocardial early systolic lengthening for diagnosis of coronary artery disease
    Masatoshi Minamisawa; Jun Koyama; Ayako Kozuka; Takashi Miura; Tatsuya Saigusa; Soichiro Ebisawa; Hirohiko Motoki; Ayako Okada; Uichi Ikeda; Koichiro Kuwahara
    OPEN HEART, 5(2), e000896, Jun. 2018WebofScienceリポジトリ電子ジャーナル
  • Atrial and brain natriuretic peptides: Hormones secreted from the heart.
    Nakagawa Y; Nishikimi T; Kuwahara K
    Peptides, 111, 18-25, May 2018, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • G蛋白サブユニットGαoのCa2+handling恒常性および心収縮能維持における意義の解明
    稲住 英明; 桑原 宏一郎; 桑原 佳宏; 中川 靖章; 木下 秀之; 錦見 俊雄; 呉林 なごみ; 山田 充彦; 柏原 俊英; 中尾 一和; 木村 剛
    日本臨床分子医学会学術総会プログラム・抄録集, 55回, 51-51, Apr. 2018
  • Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report.
    Nakagawa Y; Nishikimi T; Sakai H; Ohno S; Kinoshita H; Inazumi H; Moriuchi K; Kuwahara K; Horie M; Kimura T
    Clinical biochemistry, 52, 148-152, Feb. 2018, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Single-center experience with percutaneous lead extraction of cardiac implantable electric devices
    Ayako Okada; Morio Shoda; Hiroaki Tabata; Wataru Shoin; Hideki Kobayashi; Takahiro Okano; Koji Yoshie; Yasutaka Oguchi; Takahiro Takeuchi; Ken Kato; Koichiro Kuwahara
    JOURNAL OF CARDIOLOGY, 71(1-2), 192-196, Jan. 2018WebofScienceリポジトリ電子ジャーナル
  • Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death.
    Toshihito Fujii; Keisho Hirota; Akihiro Yasoda; Akiko Takizawa; Naomi Morozumi; Ryuichi Nakamura; Takafumi Yotsumoto; Eri Kondo; Yui Yamashita; Yoriko Sakane; Yugo Kanai; Yohei Ueda; Ichiro Yamauchi; Shigeki Yamanaka; Kazumasa Nakao; Koichiro Kuwahara; Toshimasa Jindo; Mayumi Furuya; Tomoji Mashimo; Nobuya Inagaki; Tadao Serikawa; Kazuwa Nakao
    PloS one, 13(3), e0194812, 2018, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Cross-sectional study of the association between day-to-day home blood pressure variability and visceral fat area measured using the dual impedance method
    Kuwabara J; Kuwahara K; Kuwabara Y; Yasuno S; Nakagawa Y; Ueshima K; Kimura T
    PLoS One, 13(11), e0206945, 2018, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Drug-Eluting Versus Bare-Metal Stent Implantation with or without Cilostazol in the Treatment of the Superficial Femoral Artery
    Miura T, Miyashita Y, Soga Y, Hozawa K, Doijiri T, Ikeda U, Kuwahara K on behalf of the DEBATE in SFA investigators
    Circ Cardiovasc Interv, 11(8), e006564, 2018
  • 心不全バイオマーカーとしてのBNPの臨床的意義
    桑原 宏一郎;
    診断と治療 = Diagnosis and treatment, 105(12), 1603-1607, Dec. 2017リポジトリ
  • Prognostic Value of Ankle-Brachial Index in Patients Undergoing Percutaneous Coronary Intervention: In-Hospital and 1-Year Outcomes From the SHINANO Registry
    Naoto Hashizume; Takashi Miura; Yusuke Miyashita; Hirohiko Motoki; Soichiro Ebisawa; Atsushi Izawa; Jun Koyama; Uichi Ikeda; Koichiro Kuwahara
    ANGIOLOGY, 68(10), 884-892, Nov. 2017WebofScienceリポジトリ電子ジャーナル
  • Validation of a Prognostic Risk Score for Major Bleeding Events in Patients Undergoing Percutaneous Coronary Intervention: From the SHINANO Registry
    Keisuke Senda; Takashi Miura; Tomoaki Mochidome; Takahiro Sakai; Masatoshi Minamisawa; Tamon Kato; Tatsuya Saigusa; Soichiro Ebisawa; Hirohiko Motoki; Koichiro Kuwahara
    CIRCULATION, 136, Nov. 2017WebofScienceリポジトリ
  • Cardiac hyaluronan may be associated with the persistence of atrial fibrillation
    Ayako Okada; Yuichiro Kashima; Takeshi Tomita; Takahiro Takeuchi; Yasutaka Oguchi; Koji Yoshie; Wataru Shoin; Morio Shoda; Kenichi Nitta; Koichiro Kuwahara; Hiroshi Imamura
    HEART AND VESSELS, 32(9), 1144-1150, Sep. 2017WebofScienceリポジトリ電子ジャーナル
  • Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension
    Tanabe, Nobuhiro; Ikeda, Satoshi; Tahara, Nobuhiro; Fukuda, Keiichi; Hatano, Masaru; Ito, Hiroshi; Nakayama, Tomotaka; Anzai, Toshihisa; Hashimoto, Akiyoshi; Inoue, Teruo; Kajinami, Kouji; Kihara, Yasuki; Kinoshita, Hideyuki; Kuwahara, Koichiro; Murohara, Toyoaki; Okazaki, Osamu; Sakai, Satoshi; Satoh, Toru; Takeda, Yutaka; Takeishi, Yasuchika; Taniguchi, Mitsugu; Watanabe, Hiroshi; Yamamoto, Takeshi; Yamauchi-Takihara, Keiko; Yoshioka, Koichiro; Sasayama, Shigetake
    Circulation Journal, 81(9), 1360-1367, Sep. 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Kyoto Congestive Heart Failure (KCHF) study: rationale and design
    Erika Yamamoto; Takao Kato; Neiko Ozasa; Hidenori Yaku; Yasutaka Inuzuka; Yodo Tamaki; Takeshi Kitai; Takeshi Morimoto; Ryoji Taniguchi; Moritake Iguchi; Masashi Kato; Mamoru Takahashi; Toshikazu Jinnai; Tomoyuki Ikeda; Kazuya Nagao; Takafumi Kawai; Akihiro Komasa; Ryusuke Nishikawa; Yuichi Kawase; Takashi Morinaga; Tsuneaki Kawashima; Yasuyo Motohashi; Mitsunori Kawato; Mamoru Toyofuku; Yukihito Sato; Koichiro Kuwahara; Tetsuo Shioi; Takeshi Kimura
    ESC Heart Failure, 4(3), 216-223, Aug. 2017WebofScienceリポジトリ電子ジャーナル
  • Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model
    Tatsuki Ogasawara; Satomi Okano; Hajime Ichimura; Shin Kadota; Yuki Tanaka; Itsunari Minami; Motonari Uesugi; Yuko Wada; Naoto Saito; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
    SCIENTIFIC REPORTS, 7, Aug. 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Omecamtiv mecarbil
    木村 和広; 桑原 宏一郎;
    循環器内科 = Cardioangiology, 82(2), 169-172, Aug. 2017リポジトリ
  • Diagnostic advantage of stress computed tomography myocardial perfusion over single-photon emission computed tomography for the assessment of myocardial ischemia
    Yasushi Ueki; Atsushi Izawa; Daisuke Kashiwagi; Shigeki Nishiyama; Shinichi Aso; Chihiro Suzuki; Shumpei Sakurai; Kazuhiro Oguchi; Yoshikazu Yazaki; Uichi Ikeda; Koichiro Kuwahara
    JOURNAL OF CARDIOLOGY, 70(1-2), 147-154, Jul. 2017WebofScienceリポジトリ電子ジャーナル
  • B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction
    Eisaku Harada; Yuji Mizuno; Fumihito Kugimiya; Makoto Shono; Hiroyuki Maeda; Naotsugu Yano; Koichiro Kuwahara; Hirofumi Yasue
    CIRCULATION JOURNAL, 81(7), 1006-+, Jul. 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Impressive predictive value of ankle-brachial index for very long-term outcomes in patients with cardiovascular disease: IMPACT-ABI study
    Takashi Miura; Masatoshi Minamisawa; Yasushi Ueki; Naoyuki Abe; Hitoshi Nishimura; Naoto Hashizume; Tomoaki Mochidome; Mikiko Harada; Yasutaka Oguchi; Koji Yoshie; Wataru Shoin; Tatsuya Saigusa; Soichiro Ebisawa; Hirohiko Motoki; Jun Koyama; Uichi Ikeda; Koichiro Kuwahara
    PLOS ONE, 12(6), Jun. 2017WebofScienceリポジトリ電子ジャーナル
  • Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model
    Shuji Setozaki; Kenji Minakata; Hidetoshi Masumoto; Shingo Hirao; Kazuhiro Yamazaki; Koichiro Kuwahara; Tadashi Ikeda; Ryuzo Sakata
    JOURNAL OF VASCULAR SURGERY, 65(6), 1803-1812, Jun. 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts
    Yasuaki Nakagawa; Toshio Nishikimi; Koichiro Kuwahara; Aoi Fujishima; Shogo Oka; Takayoshi Tsutamoto; Hideyuki Kinoshita; Kazuhiro Nakao; Kosai Cho; Hideaki Inazumi; Hiroyuki Okamoto; Motohiro Nishida; Takao Kato; Hiroyuki Fukushima; Jun K. Yamashita; Wino J. Wijnen; Esther E. Creemers; Kenji Kangawa; Naoto Minamino; Kazuwa Nakao; Takeshi Kimura
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 6(2), Feb. 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • MiR30-GALNT1/2 axis-mediated glycosylation contributes to the increased secretion of inactive human pro-BNP from failing hearts
    Nakagawa Y; Nishikimi T; Kuwahara K; Fujishima A; Oka S; Tsutamoto T; Kinoshita H; Nakao K; Cho K; Inazumi H; Okamoto H; Nishida M; Kato T; Fukushima H; Yamashita J; Wijnen WJ; Creemers EE; Kangawa K; Minamino N; Nakao K; Kimura T
    JAHA, 6, e003601, Feb. 2017, Refereed, Not invited
  • Unique angiographic findings in a patient with myocardial ischemia and immunoglobulin G4-related disease
    Yusuke Kanzaki; Takashi Miura; Naoto Hashizume; Tatsuya Saigusa; Soichiro Ebisawa; Koichiro Kuwahara
    SAGE OPEN MEDICAL CASE REPORTS, 5, Jan. 2017WebofScienceリポジトリ電子ジャーナル
  • Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy
    Keita P. Mori; Hideki Yokoi; Masato Kasahara; Hirotaka Imamaki; Akira Ishii; Takashige Kuwabara; Kenichi Koga; Yukiko Kato; Naohiro Toda; Shoko Ohno; Koichiro Kuwahara; Tomomi Endo; Kazuwa Nakao; Motoko Yanagita; Masashi Mukoyama; Kiyoshi Mori
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 28(1), 278-289, Jan. 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Ankle-brachial Index for the Prognosis of Cardiovascular Disease in Patients with Mild Renal Insufficiency
    Hitoshi Nishimura; Takashi Miura; Masatoshi Minamisawa; Yasushi Ueki; Naoyuki Abe; Naoto Hashizume; Tomoaki Mochidome; Mikiko Harada; Kunihiko Shimizu; Wataru Shoin; Koji Yoshie; Yasutaka Oguchi; Soichiro Ebisawa; Hirohiko Motoki; Atsushi Izawa; Jun Koyama; Uichi Ikeda; Koichiro Kuwahara
    INTERNAL MEDICINE, 56(16), 2103-2111, 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity
    Nakao K; Kuwahara K; Nishikimi T; Nakagawa Y; Kinoshita H; Minami T; Kuwabara Y; Yamada C; Yamada Y; Tokudome T
    Hypertension, 69(2), 286-296, 2017, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis
    Takuro Numaga-Tomita; Naoyuki Kitajima; Takuya Kuroda; Akiyuki Nishimura; Kei Miyano; Satoshi Yasuda; Koichiro Kuwahara; Yoji Sato; Tomomi Ide; Lutz Birnbaumer; Hideki Sumimoto; Yasuo Mori; Motohiro Nishida
    SCIENTIFIC REPORTS, 6, 39383, Dec. 2016, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Adrenomedullin
    T. Nishikimi; K. Kuwahara; Y. Nakagawa; K. Kangawa; K. Nakao
    Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart, 41-58, Nov. 2016, Refereed, Not invitedリポジトリ電子ジャーナル
  • Clinical Characteristics and Outcomes of Patients with High Ankle-Brachial Index from the IMPACT-ABI Study
    Hitoshi Nishimura; Takashi Miura; Masatoshi Minamisawa; Yasushi Ueki; Naoyuki Abe; Naoto Hashizume; Tomoaki Mochidome; Mikiko Harada; Kunihiko Shimizu; Wataru Shoin; Koji Yoshie; Yasutaka Oguchi; Soichiro Ebisawa; Hirohiko Motoki; Atsushi Izawa; Jun Koyama; Uichi Ikeda; Koichiro Kuwahara
    PLOS ONE, 11(11), Nov. 2016WebofScienceリポジトリ電子ジャーナル
  • TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling
    Naoyuki Kitajima; Takuro Numaga-Tomita; Masahiko Watanabe; Takuya Kuroda; Akiyuki Nishimura; Kei Miyano; Satoshi Yasuda; Koichiro Kuwahara; Yoji Sato; Tomomi Ide; Lutz Birnbaumer; Hideki Sumimoto; Yasuo Mori; Motohiro Nishida
    SCIENTIFIC REPORTS, 6, 37001, Nov. 2016, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Brain-specific natriuretic peptide receptor-B deletion attenuates high-fat diet-induced visceral and hepatic lipid deposition in mice
    Yui Yamashita; Nobuko Yamada-Goto; Goro Katsuura; Yukari Ochi; Yugo Kanai; Yuri Miyazaki; Koichiro Kuwahara; Naotetsu Kanamoto; Masako Miura; Akihiro Yasoda; Kousaku Ohinata; Nobuya Inagaki; Kazuwa Nakao
    PEPTIDES, 81, 38-50, Jul. 2016, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure
    Shoko Ohno; Hideki Yokoi; Kiyoshi Mori; Masato Kasahara; Koichiro Kuwahara; Junji Fujikura; Masaki Naito; Takashige Kuwabara; Hirotaka Imamaki; Akira Ishii; Moin A. Saleem; Tomohiro Numata; Yasuo Mori; Kazuwa Nakao; Motoko Yanagita; Masashi Mukoyama
    SCIENTIFIC REPORTS, 6, Jun. 2016, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy
    Chinatsu Yamada; Koichiro Kuwahara; Masatoshi Yamazaki; Yasuaki Nakagawa; Toshio Nishikimi; Hideyuki Kinoshita; Yoshihiro Kuwabara; Takeya Minami; Yuko Yamada; Junko Shibata; Kazuhiro Nakao; Kosai Cho; Yuji Arai; Haruo Honjo; Kaichiro Kamiya; Kazuwa Nakao; Takeshi Kimura
    CARDIOVASCULAR RESEARCH, 109(1), 162-173, Jan. 2016, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Myocardial Strain by 2-Dimensional Speckle Tracking Echocardiography IsUseful to Elucidate the Cause of Mitral Regurgitation in a Case of CardiacSarcoidosis
    Yoneda Tomoya; Kinoshita Hideyuki; Handa Tomohiro; Nagai Sonoko; Aizawa Takanori; Okabayashi Marie; Nakashima Yasuhiro; Nakagawa Yasuaki; Kuwahara Kouichirou; Ichiyama Satoshi; Kimura Takeshi
    The Japanese Journal of Sarcoidosis and Other Granulomatous Disorders, 36(1), 79-83, 2016リポジトリ電子ジャーナル
  • Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure
    Yasuaki Nakagawa; Shinji Yasuno; Koichiro Kuwahara
    CIRCULATION JOURNAL, 79(9), 1893-1894, Sep. 2015, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites
    Toshio Nishikimi; Yasuaki Nakagawa; Naoto Minamino; Masashi Ikeda; Kyoko Tabei; Aoi Fujishima; Kentaro Takayama; Kazumi Akimoto; Chinatsu Yamada; Kazuhiro Nakao; Takeya Minami; Yoshihiro Kuwabara; Hideyuki Kinoshita; Takayoshi Tsutamoto; Toshihiko Ishimitsu; Kenji Kangawa; Koichiro Kuwahara; Kazuwa Nakao
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 309(6), R639-R649, Sep. 2015, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The organ-protective effect of N-type Ca2+ channel blockade
    Koichiro Kuwahara; Takeshi Kimura
    PHARMACOLOGY & THERAPEUTICS, 151, 1-7, Jul. 2015, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth
    Kazumasa Nakao; Kenji Osawa; Akihiro Yasoda; Shigeki Yamanaka; Toshihito Fujii; Eri Kondo; Noriaki Koyama; Naotetsu Kanamoto; Masako Miura; Koichiro Kuwahara; Haruhiko Akiyama; Kazuhisa Bessho; Kazuwa Nakao
    SCIENTIFIC REPORTS, 5, May 2015, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2
    Kensuke Oshita; Masayuki Ltoh; Shingo Hirashima; Yoshihiro Kuwabara; Keiko Lshihara; Koichiro Kuwahara; Kazuwa Nakao; Takeshi Kimura; Kei-ichiro Nakamura; Kazuo Ushijima; Makoto Takano
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 80, 81-89, Mar. 2015, Not invitedWebofScienceリポジトリ電子ジャーナル
  • シルニジピンによる糖尿病性腎症の進行抑制機序の検討
    大野 祥子; 横井 秀基; 笠原 正登; 森 潔; 桑原 宏一郎; 塩田 文彦; 菅原 照; 中尾 一和; 柳田 素子; 向山 政志
    日本内科学会雑誌, 104(Suppl.), 264-264, Feb. 2015
  • Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model
    Miwa Tanaka; Shuichi Yamaguchi; Yukari Yamazaki; Hideyuki Kinoshita; Koichiro Kuwahara; Kazuwa Nakao; Patrick Y. Jay; Tetsuo Noda; Takuro Nakamura
    SCIENTIFIC REPORTS, 5, Jan. 2015, Not invitedWebofScienceリポジトリ電子ジャーナル
  • TRP Channels: Their Function and Potentiality as Drug Targets
    Motohiro Nishida; Koichiro Kuwahara; Daisuke Kozai; Reiko Sakaguchi; Yasuo Mori
    195-218, 2015リポジトリ電子ジャーナル
  • 僧帽弁逆流の成因解明にストレインエコーが有用であった心サルコイドーシスの一症例
    米田 智也; 木下 秀之; 半田 知宏; ⻑井 苑子; 相澤 卓範; 岡林 真梨恵; 中島 康弘; 中川 靖章; 桑原 宏一郎; 一山 智; 木村 剛
    日本サルコイドーシス/肉芽腫性疾患学会雑誌, 35(1), 69-3-69-3, 2015リポジトリ電子ジャーナル
  • 僧帽弁逆流の成因解明にストレインエコーが有用であった心サルコイドーシスの1症例
    米田智也; 木下秀之; 相澤卓範; 岡林真梨恵; 中島康弘; 山田千夏; 今井逸雄; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 一山智; 木村剛
    日本循環器学会近畿地方会(Web), 120th, KINKI120,C25 (WEB ONLY), 2015, Not invitedリポジトリ
  • 肺胞蛋白症に肺高血圧症を合併した一例
    北野一樹; 木下秀之; 谷澤公伸; 大原弘喜; 辰島正二郎; 山田千夏; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛
    日本循環器学会近畿地方会(Web), 120th, KINKI120,H22 (WEB ONLY), 2015, Not invitedリポジトリ
  • Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure
    Yuko Yamada; Hideyuki Kinoshita; Koichiro Kuwahara; Yasuaki Nakagawa; Yoshihiro Kuwabara; Takeya Minami; Chinatsu Yamada; Junko Shibata; Kazuhiro Nakao; Kosai Cho; Yuji Arai; Shinji Yasuno; Toshio Nishikimi; Kenji Ueshima; Shiro Kamakura; Motohiro Nishida; Shigeki Kiyonaka; Yasuo Mori; Takeshi Kimura; Kenji Kangawa; Kazuwa Nakao
    CARDIOVASCULAR RESEARCH, 104(1), 183-193, Oct. 2014, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The Effects of Super-Flux (High Performance) Dialyzer on Plasma Glycosylated Pro-B-Type Natriuretic Peptide (proBNP) and Glycosylated N-Terminal proBNP in End-Stage Renal Disease Patients on Dialysis
    Yasuaki Nakagawa; Toshio Nishikimi; Koichiro Kuwahara; Shinji Yasuno; Hideyuki Kinoshita; Yoshihiro Kuwabara; Kazuhiro Nakao; Takeya Minami; Chinatsu Yamada; Kenji Ueshima; Yoshihiro Ikeda; Hiroyuki Okamoto; Kazukiyo Horii; Kiyoshi Nagata; Kenji Kangawa; Naoto Minamino; Kazuwa Nakao
    PLOS ONE, 9(3), Mar. 2014, Not invitedWebofScienceリポジトリ電子ジャーナル
  • 全身性強皮症に合併した肺高血圧症に対し原因の鑑別を行った1症例
    脊古裕太; 木下秀之; 山田千夏; 中川靖章; 静田聡; 尾野亘; 塩井哲雄; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 118th, KINKI118,F30 (WEB ONLY), 2014, Not invitedリポジトリ
  • Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy
    Shinji Yasuno; Koichiro Kuwahara; Hideyuki Kinoshita; Chinatsu Yamada; Yasuaki Nakagawa; Satoru Usami; Yoshihiro Kuwabara; Kenji Ueshima; Masaki Harada; Toshio Nishikimi; Kazuwa Nakao
    BRITISH JOURNAL OF PHARMACOLOGY, 170(7), 1384-1395, Dec. 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Identification of chemicals inducing cardiomyocyte proliferation in developmental stage-specific manner with pluripotent stem cells
    Hideki Uosaki; Ajit Magadum; Kinya Seo; Hiroyuki Fukushima; Ayako Takeuchi; Yasuaki Nakagawa; Kara White Moyes; Genta Narazaki; Koichiro Kuwahara; Michael Laflamme; Satoshi Matsuoka; Norio Nakatsuji; Kazuwa Nakao; Chulan Kwon; David A. Kass; Felix B. Engel; Jun K. Yamashita
    Circulation: Cardiovascular Genetics, 6(6), 624-633, Dec. 2013, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure
    Akira Funayama; Tetsuro Shishido; Shunsuke Netsu; Taro Narumi; Shinpei Kadowaki; Hiroki Takahashi; Takuya Miyamoto; Tetsu Watanabe; Chang-Hoon Woo; Jun-ichi Abe; Koichiro Kuwahara; Kazuwa Nakao; Yasuchika Takeishi; Isao Kubota
    CARDIOVASCULAR RESEARCH, 99(4), 657-664, Sep. 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Angiotensin II-induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16
    Emi Matsumoto; Sayaka Sasaki; Hideyuki Kinoshita; Takuya Kito; Hiroya Ohta; Morichika Konishi; Koichiro Kuwahara; Kazuwa Nakao; Nobuyuki Itoh
    GENES TO CELLS, 18(7), 544-553, Jul. 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts
    Yoshihiro Kuwabara; Koichiro Kuwahara; Makoto Takano; Hideyuki Kinoshita; Yuji Arai; Shinji Yasuno; Yasuaki Nakagawa; Sachiyo Igata; Satoru Usami; Takeya Minami; Yuko Yamada; Kazuhiro Nakao; Chinatsu Yamada; Junko Shibata; Toshio Nishikimi; Kenji Ueshima; Kazuwa Nakao
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2(3), Jun. 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice
    Motohiro Nishida; Tatsuya Ishikawa; Shota Saiki; Caroline Sunggip; Shizuka Aritomi; Eri Harada; Koichiro Kuwahara; Katsuya Hirano; Yasuo Mori; Shokei Kim-Mitsuyama
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 434(2), 210-216, May 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Complexity of molecular forms of B-type natriuretic peptide in heart failure
    Toshio Nishikimi; Koichiro Kuwahara; Yasuaki Nakagawa; Kenji Kangawa; Naoto Minamino; Kazuwa Nakao
    HEART, 99(10), 677-679, May 2013, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Direct Immunochemiluminescent Assay for proBNP and Total BNP in Human Plasma proBNP and Total BNP Levels in Normal and Heart Failure
    Toshio Nishikimi; Hiroyuki Okamoto; Masahiro Nakamura; Naoko Ogawa; Kazukiyo Horii; Kiyoshi Nagata; Yasuaki Nakagawa; Hideyuki Kinoshita; Chinatsu Yamada; Kazuhiro Nakao; Takeya Minami; Yoshihiro Kuwabara; Koichiro Kuwahara; Izuru Masuda; Kenji Kangawa; Naoto Minamino; Kazuwa Nakao
    PLOS ONE, 8(1), Jan. 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Determination of the B-type natriuretic peptide level as a criterion for abnormalities in Japanese individuals in routine clinical practice: The J-ABS multi-center study (Japan Abnormal BNP Standard)
    Makoto Kawai; Michihiro Yoshimura; Masaki Harada; Yuji Mizuno; Shinya Hiramitsu; Mitsuyuki Shimizu; Toru Shoda; Koichiro Kuwahara; Kenji Miyagishima; Kenji Ueshima; Kazuwa Nakao
    Internal Medicine, 52(2), 171-177, 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Role of NRSF/REST in the regulation of cardiac gene expression and function
    Koichiro Kuwahara
    Circulation Journal, 77(11), 2682-2686, 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Adrenomedullin in cardiovascular disease: A useful biomarker, its pathological roles and therapeutic application
    Toshio Nishikimi; Koichiro Kuwahara; Yasuaki Nakagawa; Kenji Kangawa; Kazuwa Nakao
    Current Protein and Peptide Science, 14(4), 256-267, 2013, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Ca2+ channels as novel therapeutic targets in heart failure
    K. Kuwahara
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 140(6), 255-258, Dec. 2012, Refereed, Not invitedリポジトリ電子ジャーナル
  • Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice
    Takeya Minami; Koichiro Kuwahara; Yasuaki Nakagawa; Minoru Takaoka; Hideyuki Kinoshita; Kazuhiro Nakao; Yoshihiro Kuwabara; Yuko Yamada; Chinatsu Yamada; Junko Shibata; Satoru Usami; Shinji Yasuno; Toshio Nishikimi; Kenji Ueshima; Masataka Sata; Hiroyasu Nakano; Takahiro Seno; Yutaka Kawahito; Kenji Sobue; Akinori Kimura; Ryozo Nagai; Kazuwa Nakao
    EMBO JOURNAL, 31(23), 4428-4440, Nov. 2012, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • [109th Scientific Meeting of the Japanese Society of Internal Medicine: symposium: 2. Translational research and evidence-based medicine (EBM) in internal medicine in Japan, translational research; 4) Translational research of endocrinology and metabolism
    Kiminori Hosoda; Akihiro Yasoda; Ken Ebihara; Koichiro Kuwahara; Masashi Mukouyama; Kazuwa Nakao
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 101, 2552-2562, Sep. 2012, Not invitedリポジトリ
  • In vivo Site-Specific Transfection of Naked Plasmid DNA and siRNAs in Mice by Using a Tissue Suction Device
    Kazunori Shimizu; Shigeru Kawakami; Kouji Hayashi; Hideyuki Kinoshita; Koichiro Kuwahara; Kazuwa Nakao; Mitsuru Hashida; Satoshi Konishi
    PLOS ONE, 7(7), Jul. 2012, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Transcriptional Regulation of the Fetal Cardiac Gene Program
    Koichiro Kuwahara; Toshio Nishikimi; Kazuwa Nakao
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 119(3), 198-203, Jul. 2012, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Fixed-dose combination therapy of candesartan cilexetil and amlodipine besilate for the treatment of hypertension in Japan
    Shinji Yasuno; Akira Fujimoto; Yasuaki Nakagawa; Koichiro Kuwahara; Kenji Ueshima
    Expert Review of Cardiovascular Therapy, 10(5), 577-583, May 2012, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Current biochemistry, molecular biology, and clinical relevance if natriuretic peptides (vol 57, pg 131, 2011)
    Toshio Nishikimi; Koichiro Kuwahara; Kazuwa Nakao
    JOURNAL OF CARDIOLOGY, 59(1), 98-99, Jan. 2012, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure
    Toshio Nishikimi; Masashi Ikeda; Yosuke Takeda; Toshihiko Ishimitsu; Ikuko Shibasaki; Hirotsugu Fukuda; Hideyuki Kinoshita; Yasuaki Nakagawa; Koichiro Kuwahara; Kazuwa Nakao
    HEART, 98(2), 152-161, Jan. 2012, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • ユーイング肉腫特異的なEws-Fli1転座マウスは拡張型心筋症を発症する(A mouse model for Ewing's sarcoma-specific Ews-Fli1 so matic translocation develops dilated cardiomyopathy)
    田中 美和; 野田 哲生; 木下 秀之; 桑原 宏一郎; 中尾 一和; 中村 卓郎
    日本癌学会総会記事, 70回, 159-159, Sep. 2011, Refereed, Not invited
  • TRPC3/6 as Potentially Novel Therapeutic Targets for The Treatment of Pulmonary Arterial Hypertension
    Hideyuki Kinoshita; Koichiro Kuwahara; Shigeki Kiyonaka; Yasuo Mori; Yoshihiro Kuwabara; Satoru Usami; Yasuaki Nakagawa; Toshio Nishikimi; Kenji Ueshima; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 17(9), S153, Sep. 2011, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • New Molecular Mechanisms for Cardiovascular Disease: Transcriptional Pathways and Novel Therapeutic Targets in Heart Failure
    Koichiro Kuwahara; Kazuwa Nakao
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 116(4), 337-342, Aug. 2011, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
    Leo Hata; Masao Murakami; Koichiro Kuwahara; Yasuaki Nakagawa; Hideyuki Kinoshita; Satoru Usami; Shinji Yasuno; Masataka Fujiwara; Yoshihiro Kuwabara; Takeya Minami; Yuko Yamada; Chinatsu Yamada; Kazuhiro Nakao; Kenji Ueshima; Toshio Nishikimi; Kazuwa Nakao
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 50(6), 972-981, Jun. 2011, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Current biochemistry, molecular biology, and clinical relevance of natriuretic peptides
    Toshio Nishikimi; Koichiro Kuwahara; Kazuwa Nakao
    JOURNAL OF CARDIOLOGY, 57(2), 131-140, Mar. 2011, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A
    Masataka Fujiwara; Peishi Yan; Tomomi G. Otsuji; Genta Narazaki; Hideki Uosaki; Hiroyuki Fukushima; Koichiro Kuwahara; Masaki Harada; Hiroyuki Matsuda; Satoshi Matsuoka; Keisuke Okita; Kazutoshi Takahashi; Masato Nakagawa; Tadashi Ikeda; Ryuzo Sakata; Christine L. Mummery; Norio Nakatsuji; Shinya Yamanaka; Kazuwa Nakao; Jun K. Yamashita
    PLOS ONE, 6(2), e16734, Feb. 2011, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • N-Type Ca2+ Channel Blockade Prevents Sudden Death in Mice with Heart Failure
    Yuko Yamada; Koichiro Kuwahara; Hideyuki Kinoshita; Yoshihiro Kuwabara; Yasuaki Nakagawa; Junko Shibata; Chinatsu Yamada; Takeya Minami; Satoshi Usami; Kazuyasu Nakao; Toshio Nishikimi; Kazuwa Nakao
    journal of arrhythmia, 27(4), 209, 2011, Refereed, Not invitedリポジトリ電子ジャーナル
  • Inhibition of HCN Overexpressed in Failing Heart of Dilated Cardiomyopathy Mouse Model by Ivabradine Prevents Sudden Arrhythmic Death
    Yoshihiro Kuwabara; Koichiro Kuwahara; Makoto Takano; Hidayuki Kinoshita; Yasuaki Nakagawa; Satoru Usami; Kazuhiro Nakao; Takeya Minami; Toshio Nishikimi; Kazuwa Nakao
    journal of arrhythmia, 27(4), 424, 2011, Refereed, Not invitedリポジトリ電子ジャーナル
  • G alpha(12/13) mediate pressure overload-induced cardiac fibrosis through 4-hydroxy-2-nonenal production in cardiac fibroblasts
    Takashi Mishima; Motohiro Nishida; Koichiro Kuwahara; Michio Nakaya; Yoji Sato; Takahiro Shibata; Koji Uchida; Hitoshi Kurose
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 115, 203P-203P, 2011, Refereed, Not invitedWebofScienceリポジトリ
  • Pathophysiological Remodeling of Mouse Cardiac Myocytes Expressing Dominant Negative Mutant of Neuron Restrictive Silencing Factor
    Makoto Takano; Hideyuki Kinoshita; Takao Shioya; Masayuki Itoh; Kazuwa Nakao; Koichiro Kuwahara
    CIRCULATION JOURNAL, 74(12), 2712-2719, Dec. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Natriuretic Peptides-Guanylyl Cyclase-A Signaling Pathway Inhibits TRPC6-Mediated Pro-Hypertrophic Signaling in the Hearts
    Kinoshita Hideyuki; Kuwahara Koichiro; Nishida Motohiro; Kurose Hitoshi; Zhong Jian; Inoue Ryuji; Kiyonaka Shigeki; Mori Yasuo; Rong Xianglu; Li Yuhao; Yamada Chinatsu; Yamada Yuko; Minami Takeya; Kuwabara Yoshihiro; Fujiwara Masataka; Yasuno Shinji; Usami Satoru; Nakagawa Yasuaki; Nishikimi Toshio; Ueshima Kenji; Nakao Kazuwa
    CIRCULATION, 122(21), Nov. 2010, Refereed, Not invitedWebofScienceリポジトリ
  • Blockade of TRPC6 is a Novel Therapeutic Approach Against Pathological Cardiac Remodeling
    Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Hitoshi Kurose; Shigeki Kiyonaka; Yasuo Mori; Satoru Usami; Yasuaki Nakagawa; Kenji Ueshima; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 16(9), Sep. 2010, Not invited
  • Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression
    Koichiro Kuwahara; Hideyuki Kinoshita; Yoshihiro Kuwabara; Yasuaki Nakagawa; Satoru Usami; Takeya Minami; Yuko Yamada; Masataka Fujiwara; Kazuwa Nakao
    MOLECULAR AND CELLULAR BIOLOGY, 30(17), 4134-4148, Sep. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice
    X. Rong; Y. Li; K. Ebihara; M. Zhao; J. Naowaboot; T. Kusakabe; K. Kuwahara; M. Murray; K. Nakao
    DIABETOLOGIA, 53(8), 1727-1731, Aug. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Podocyte-specific expression of tamoxifen-inducible Cre recombinase in mice
    Hideki Yokoi; Masato Kasahara; Masashi Mukoyama; Kiyoshi Mori; Koichiro Kuwahara; Junji Fujikura; Yuji Arai; Yoko Saito; Yoshihisa Ogawa; Takashige Kuwabara; Akira Sugawara; Kazuwa Nakao
    NEPHROLOGY DIALYSIS TRANSPLANTATION, 25(7), 2120-2124, Jul. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Regulation and significance of atrial and brain natriuretic peptides as cardiac hormones
    Koichiro Kuwahara; Kazuwa Nakao
    ENDOCRINE JOURNAL, 57(7), 555-565, Jul. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction
    Eric M. Small; Jeffrey E. Thatcher; Lillian B. Sutherland; Hideyuki Kinoshita; Robert D. Gerard; James A. Richardson; J. Michael DiMaio; Hesham Sadek; Koichiro Kuwahara; Eric N. Olson
    CIRCULATION RESEARCH, 107(2), 294-U263, Jul. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart
    Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Zhong Jian; Xianglu Rong; Shigeki Kiyonaka; Yoshihiro Kuwabara; Hitoshi Kurose; Ryuji Inoue; Yasuo Mori; Yuhao Li; Yasuaki Nakagawa; Satoru Usami; Masataka Fujiwara; Yuko Yamada; Takeya Minami; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION RESEARCH, 106(12), 1849-U153, Jun. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Atrial and brain natriuretic peptides-guanylyl cyclase-A signaling pathway inhibits TRPC6-mediated pro-hypertrophic signaling in the hearts
    Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Zhong Jiang; Xianglu Rong; Shigeki Kiyonaka; Yoshihiro Kuwabara; Hitoshi Kurose; Ryuji Inoue; Yasuo Mori; Yuhao Li; Yasuaki Nakagawa; Satoru Usami; Kenji Ueshima; Kazuwa Nakao
    ENDOCRINE JOURNAL, 57, Mar. 2010, Not invited
  • Vasodilator therapy with hydralazine induces angiotensin AT(2) receptor-mediated cardiomyocyte growth in mice lacking guanylyl cyclase-A
    Y. Li; Y. Saito; K. Kuwahara; X. Rong; I. Kishimoto; M. Harada; M. Horiuchi; M. Murray; K. Nakao
    BRITISH JOURNAL OF PHARMACOLOGY, 159(5), 1133-1142, Mar. 2010, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • p300 Plays a Critical Role in Maintaining Cardiac Mitochondrial Function and Cell Survival in Postnatal Hearts
    Yasuaki Nakagawa; Koichiro Kuwahara; Genzo Takemura; Masaharu Akao; Masashi Kato; Yuji Arai; Makoto Takano; Masaki Harada; Masao Murakami; Michio Nakanishi; Satoru Usami; Shinji Yasuno; Hideyuki Kinoshita; Masataka Fujiwara; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION RESEARCH, 105(8), 746-U57, Oct. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Cardiac Natriuretic Peptides Inhibit TRPC6-Mediated Prohypertrophic Signaling
    Hideyuki Kinoshita; Koichiro Kuwahara; Ryuji Inoue; Motohiro Nishida; Hitoshi Kurose; Shigeki Kiyonaka; Yasuo Mori; Masaki Harada; Masao Murakami; Yasuaki Nakagawa; Shinji Yasuno; Satoru Usami; Masataka Fujiwara; Yoshihiro Kuwabara; Takeya Minami; Yuko Yamada; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION RESEARCH, 105(7), E47, Sep. 2009, Refereed, Not invitedWebofScienceリポジトリ
  • T-Type Ca2+ Channel Blockade Prevents Sudden Death in Mice With Heart Failure
    Hideyuki Kinoshita; Koichiro Kuwahara; Makoto Takano; Yuji Arai; Yoshihiro Kuwabara; Shinji Yasuno; Yasuaki Nakagawa; Michio Nakanishi; Masaki Harada; Masataka Fujiwara; Masao Murakami; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION, 120(9), 743-U66, Sep. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2
    Shinobu Kuratomi; Yoko Ohmori; Masayuki Ito; Kuniko Shimazaki; Shin-ichi Muramatsu; Hiroaki Mizukami; Hideki Uosaki; Jun K. Yamashita; Yuji Arai; Koichiro Kuwahara; Makoto Takano
    CARDIOVASCULAR RESEARCH, 83(4), 682-687, Sep. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2
    Shinobu Kuratomi; Yoko Ohmori; Masayuki Ito; Kuniko Shimazaki; Shin-ichi Muramatsu; Hiroaki Mizukami; Hideki Uosaki; Jun K. Yamashita; Yuji Arai; Koichiro Kuwahara; Makoto Takano
    CARDIOVASCULAR RESEARCH, 83(4), 682-687, Sep. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Guanylyl Cyclase-A Inhibits Angiotensin II Type 2 Receptor-Mediated Pro-Hypertrophic Signaling in the Heart
    Yuhao Li; Yoshihiko Saito; Koichiro Kuwahara; Xianglu Rong; Ichiro Kishimoto; Masaki Harada; Yuichiro Adachi; Michio Nakanishi; Hideyuki Kinoshita; Masatsugu Horiuchi; Michael Murray; Kazuwa Nakao
    ENDOCRINOLOGY, 150(8), 3759-3765, Aug. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death
    Shinji Yasuno; Satoru Usami; Koichiro Kuwahara; Michio Nakanishi; Yuji Arai; Hideyuki Kinoshita; Yasuaki Nakagawa; Masataka Fujiwara; Masao Murakami; Kenji Ueshima; Masaki Harada; Kazuwa Nakao
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 296(6), H1804-H1810, Jun. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death
    Shinji Yasuno; Satoru Usami; Koichiro Kuwahara; Michio Nakanishi; Yuji Arai; Hideyuki Kinoshita; Yasuaki Nakagawa; Masataka Fujiwara; Masao Murakami; Kenji Ueshima; Masaki Harada; Kazuwa Nakao
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 296(6), H1804-H1810, Jun. 2009, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Fgf16 Is Required for Cardiomyocyte Proliferation in the Mouse Embryonic Heart
    Yuhei Hotta; Sayaka Sasaki; Morichika Konishi; Hideyuki Kinoshita; Koichiro Kuwahara; Kazuwa Nakao; Nobuyuki Itoh
    DEVELOPMENTAL DYNAMICS, 237(10), 2947-2954, Oct. 2008, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Association of CT dinucleotide repeat polymorphism in the 5'-flanking region of the guanylyl cyclase (GC)-A gene with essential hypertension in the Japanese
    Satoru Usami; Ichiro Kishimoto; Yoshihiko Saito; Masaki Harada; Koichiro Kuwahara; Yasuaki Nakagawa; Michio Nakanishi; Shinji Yasuno; Kenji Kangawa; Kazuwa Nakao
    HYPERTENSION RESEARCH, 31(1), 89-96, Jan. 2008, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • A case report of right ventricular perforation 6 months after permanent pacemaker implantation
    M. Nakanishi; M. Harada; K. Kuwahara; Y. Nakagawa; S. Usami; H. Kinoshita; M. Fujiwara; K. Nakao; N. Marui; K. Tambara; K. Nishina; M. Komeda; K. Ueshima
    Respiration and circulation, 56(8), 861-865, 2008, Refereed, Not invitedリポジトリ電子ジャーナル
  • Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation
    Michio Nakanishi; Masaki Harada; Ichiro Kishimoto; Koichiro Kuwahara; Rika Kawakami; Yasuaki Nakagawa; Shinji Yasuno; Satoru Usami; Hideyuki Kinoshita; Yuichiro Adachi; Akiyoshi Fukamizu; Yoshihiko Saito; Kazuwa Nakao
    CIRCULATION JOURNAL, 71(8), 1310-1316, Aug. 2007, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance
    Michio Nakanishi; Masaki Harada; Eiji Tadamura; Hirokazu Kotani; Rika Kawakami; Koichiro Kuwahara; Yasuaki Nakagawa; Satoru Usami; Hideyuki Kinoshita; Masataka Fujiwara; Kiminori Hosoda; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION, 116(2), E25-E26, Jul. 2007, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity
    Koichiro Kuwahara; Gordon C. Teg Pipes; John McAnally; James A. Richardson; Joseph A. Hill; Rhonda Bassel-Duby; Eric N. Olson
    JOURNAL OF CLINICAL INVESTIGATION, 117(5), 1324-1334, May 2007, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin
    Tomasa Barrientos; Derk Frank; Koichiro Kuwahara; Svetlana Bezprozvannaya; G. C. Teg Pipes; Rhonda Bassel-Duby; James A. Richardson; Hugo A. Katus; Eric N. Olson; Norbert Frey
    JOURNAL OF BIOLOGICAL CHEMISTRY, 282(11), 8393-8403, Mar. 2007, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes
    Shinobu Kuratomi; Akiko Kuratomi; Koichiro Kuwahara; Takahiro M. Ishii; Kazuwa Nakao; Yoshihiko Saito; Makoto Takano
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 353(1), 67-73, Feb. 2007, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
    Koichiro Kuwahara; Yanggan Wang; John McAnally; James A. Richardson; Rhonda Bassel-Duby; Joseph A. Hill; Eric N. Olson
    JOURNAL OF CLINICAL INVESTIGATION, 116(12), 3114-3126, Dec. 2006, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes
    Yasuaki Nakagawa; Koichiro Kuwahara; Masaki Harada; Nobuki Takahashi; Shinji Yasuno; Yuichiro Adachi; Rika Kawakami; Michio Nakanishi; Keiji Tanimoto; Satoru Usami; Hideyuki Kinoshita; Yoshihiko Saito; Kazuwa Nakao
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 41(6), 1010-1022, Dec. 2006, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Blockade of T-type calcium channel suppressed the arrhythmogenicity in dominant negative NRSF transgenic mice
    Kinoshita Hideyuki; Kuwahara Kouichirou; Harada Masaki; Horie Minoru; Nakagawa Yasuaki; Nakanishi Michio; Usami Satoru; Fujiwara Masataka; Ueshima Kenji; Nakao Kazuwa
    JOURNAL OF CARDIAC FAILURE, 12(8), S163, Oct. 2006, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Blockade of angiotensin II type 1 receptor improves the arrhythmia morbidity in mice with left ventricular hypertrophy
    CT Zhang; S Yasuno; K Kuwahara; DP Zankov; A Kobori; T Makiyama; M Horie
    CIRCULATION JOURNAL, 70(3), 335-341, Mar. 2006, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK
    TA McKinsey; K Kuwahara; S Bezprozvannaya; EN Olson
    MOLECULAR BIOLOGY OF THE CELL, 17(1), 438-447, Jan. 2006, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Pathophysiological significance of T-type Ca2+ channels: Transcriptional regulation of T-type Ca2+ channel - Regulation of CACNA1H by neuron-restrictive silencer factor
    K Kuwahara; M Takano; K Nakao
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 99(3), 211-213, Nov. 2005, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo
    K Tanimoto; Y Saito; Hamanaka, I; K Kuwahara; M Harada; N Takahashi; R Kawakami; Y Nakagawa; M Nakanishi; Y Adachi; G Shirakami; K Fukuda; A Yoshimura; K Nakao
    CIRCULATION JOURNAL, 69(11), 1412-1417, Nov. 2005, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice
    M Nakanishi; Y Saito; Kishimoto, I; M Harada; K Kuwahara; N Takahashi; R Kawakami; Y Nakagawa; K Tanimoto; S Yasuno; S Usami; YH Li; Y Adachi; A Fukamizu; DL Garbers; K Nakao
    HYPERTENSION, 46(2), 441-447, Aug. 2005, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Muscle-specific signaling mechanism that links actin dynamics to serum response factor
    K Kuwahara; T Barrientos; GCT Pipes; S Li; EN Olson
    MOLECULAR AND CELLULAR BIOLOGY, 25(8), 3173-3181, Apr. 2005, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes
    N Takahashi; Y Saito; K Kuwahara; M Harada; K Tanimoto; Y Nakagawa; R Kawakami; M Nakanishi; S Yasuno; S Usami; A Yoshimura; K Nakao
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 38(1), 185-192, Jan. 2005, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Overexpression of brain natriuretic peptide facilitates neutrophil infiltration and cardiac matrix metalloproteinase-9 expression after acute myocardial infarction
    R Kawakami; Y Saito; Kishimoto, I; M Harada; K Kuwahara; N Takahashi; Y Nakagawa; M Nakanishi; K Tanimoto; S Usami; S Yasuno; H Kinoshita; H Chusho; N Tamura; Y Ogawa; K Nakao
    CIRCULATION, 110(21), 3306-3312, Nov. 2004, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Androgen contributes to gender-related cardiac hypertrophy and fibrosis in mice lacking the gene encoding guanylyl cyclase-A
    YH Li; Kishimoto, I; Y Saito; M Harada; K Kuwahara; T Izumi; Hamanaka, I; N Takahashi; R Kawakami; K Tanimoto; Y Nakagawa; M Nakanishi; Y Adachi; DL Garbers; A Fukamizu; K Nakao
    ENDOCRINOLOGY, 145(2), 951-958, Feb. 2004, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Regulation of natriuretic peptide gene expression
    K. Kuwahara; K. Nakao
    Nippon rinsho. Japanese journal of clinical medicine, 62 Suppl 9, 28-30, 2004, Refereed, Not invitedリポジトリ
  • NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function
    K Kuwahara; Y Saito; M Takano; Y Arai; S Yasuno; Y Nakagawa; N Takahashi; Y Adachi; G Takemura; M Horie; Y Miyamoto; T Morisaki; S Kuratomi; A Noma; H Fujiwara; Y Yoshimasa; H Kinoshita; R Kawakami; Kishimoto, I; M Nakanishi; S Usami; Y Saito; M Harada; K Nakao
    EMBO JOURNAL, 22(23), 6310-6321, Dec. 2003, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Angiotensin II-induced ventricular hypertrophy and extracellular signal-regulated kinase activation are suppressed in mice overexpressing brain natriuretic peptide in circulation
    N Takahashi; Y Saito; K Kuwahara; M Harada; Kishimoto, I; Y Ogawa; R Kawakami; Y Nakagawa; M Nakanishi; K Nakao
    HYPERTENSION RESEARCH, 26(10), 847-853, Oct. 2003, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Angiotensin II type 2 receptor deficiency exacerbates heart failure and reduces survival after acute myocardial infarction in mice
    Y Adachi; Y Saito; Kishimoto, I; M Harada; K Kuwahara; N Takahashi; R Kawakami; M Nakanishi; Y Nakagawa; K Tanimoto; Y Saitoh; S Yasuno; S Usami; M Iwai; M Horiuchi; K Nakao
    CIRCULATION, 107(19), 2406-2408, May 2003, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Prognostic and clinical significance of newly acquired complete right bundle branch block in Japan airline pilots
    M Taniguchi; H Nakano; K Kuwahara; Masuda, I; Y Okawa; H Miyazaki; H Okoshi; M Kaji; Y Noguchi; Asukata, I
    INTERNAL MEDICINE, 42(1), 21-24, Jan. 2003, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart
    YH Li; Kishimoto, I; Y Saito; M Harada; K Kuwahara; T Izumi; N Takahashi; R Kawakami; K Tanimoto; Y Nakagawa; M Nakanishi; Y Adachi; DL Garbers; A Fukamizu; K Nakao
    CIRCULATION, 106(13), 1722-1728, Sep. 2002, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Fibronectin signaling stimulates BNP gene transcription by inhibiting neuron-restrictive silencer element-dependent repression
    E Ogawa; Y Saito; K Kuwahara; M Harada; Y Miyamoto; Hamanaka, I; N Kajiyama; N Takahashi; T Izumi; R Kawakami; Kishimoto, I; Y Naruse; N Mori; K Nakao
    CARDIOVASCULAR RESEARCH, 53(2), 451-459, Feb. 2002, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Relationship between plasma level of cardiotrophin-1 and left ventricular mass index in patients with dilated cardiomyopathy
    T Tsutamoto; A Wada; K Maeda; N Mabuchi; M Hayashi; T Tsutsui; M Ohnishi; M Fujii; T Matsumoto; T Yamamoto; XW Wang; S Asai; T Tsuji; H Tanaka; Y Saito; K Kuwahara; K Nakao; M Kinoshita
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 38(5), 1485-1490, Nov. 2001, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes
    E Harada; M Yoshimura; H Yasue; O Nakagawa; M Nakagawa; M Harada; Y Mizuno; M Nakayama; Y Shimasaki; T Ito; S Nakamura; K Kuwahara; Y Saito; K Nakao; H Ogawa
    CIRCULATION, 104(2), 137-139, Jul. 2001, Refereed, Not invitedWebofScienceリポジトリ
  • Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-kappa B activation and alleviates myocardial ischemia/reperfusion injury
    T Izumi; Y Saito; Kishimoto, I; M Harada; K Kuwahara; Hamanaka, I; N Takahashi; R Kawakami; YH Li; G Takemura; H Fujiwara; DL Garbers; S Mochizuki; K Nakao
    JOURNAL OF CLINICAL INVESTIGATION, 108(2), 203-213, Jul. 2001, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Induction of JAB/SOCS-1/SSI-1 and CIS3/SOCS-3/SSI-3 is involved in gp130 resistance in cardiovascular system in rat treated with cardiotrophin-1 in vivo
    Hamanaka, I; Y Saito; H Yasukawa; Kishimoto, I; K Kuwahara; Y Miyamoto; M Harada; E Ogawa; N Kajiyama; N Takahashi; T Izumi; R Kawakami; Masuda, I; A Yoshimura; K Nakao
    CIRCULATION RESEARCH, 88(7), 727-732, Apr. 2001, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The neuron-restrictive silencer element-neuron-restrictive silencer factor system regulates basal and endothelin 1-inducible atrial natriuretic peptide gene expression in ventricular myocytes
    K Kuwahara; Y Saito; E Ogawa; N Takahashi; Y Nakagawa; Y Naruse; M Harada; Hamanaka, I; T Izumi; Y Miyamoto; Kishimoto, I; R Kawakami; M Nakanishi; N Mori; K Nakao
    MOLECULAR AND CELLULAR BIOLOGY, 21(6), 2085-2097, Mar. 2001, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • The heart is a source of circulating cardiotrophin-1 in humans
    S Asai; Y Saito; K Kuwahara; Y Mizuno; M Yoshimura; C Higashikubo; T Tsuji; Kishimoto, I; M Harada; Hamanaka, I; N Takahashi; H Yasue; K Nakao
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 279(2), 320-323, Dec. 2000, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a-786T -> C mutation associated with coronary spastic angina
    Y Miyamoto; Y Saito; M Nakayama; Y Shimasaki; T Yoshimura; M Yoshimura; M Harada; N Kajiyama; Kishimoto, I; K Kuwahara; J Hino; E Ogawa; Hamanaka, I; S Kamitani; N Takahashi; R Kawakami; K Kangawa; H Yasue; K Nakao
    HUMAN MOLECULAR GENETICS, 9(18), 2629-2637, Nov. 2000, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Lack of association between T-786 -> C mutation in the 5 '-flanking region of the endothelial nitric oxide synthase gene and essential hypertension
    N Kajiyama; Y Saito; Y Miyamoto; M Yoshimura; M Nakayama; M Harada; K Kuwahara; Kishimoto, I; H Yasue; K Nakao
    HYPERTENSION RESEARCH, 23(6), 561-565, Nov. 2000, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Cardiotrophin-1 phosphorylates Akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes
    K Kuwahara; Y Saito; Kishimoto, I; Y Miyamoto; M Harada; E Ogawa; Hamanaka, I; N Kajiyama; N Takahashi; T Izumi; R Kawakami; K Nakao
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 32(8), 1385-1394, Aug. 2000, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Effects of cardiotrophin-1 on hemodynamics and endocrine function of the heart
    Hamanaka, I; Y Saito; T Nishikimi; T Magaribuchi; S Kamitani; K Kuwahara; M Ishikawa; Y Miyamoto; M Harada; E Ogaea; N Kajiyama; N Takahashi; T Izumi; G Shirakami; K Mori; Y Inobe; Kishimoto, I; Masuda, I; K Fukuda; K Nakao
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 279(1), H388-H396, Jul. 2000, Refereed, Not invitedWebofScienceリポジトリ
  • Outside-in signalling of fibronectin stimulates cardiomyocyte hypertrophy in cultured neonatal rat ventricular myocytes
    E Ogawa; Y Saito; M Harada; S Kamitani; K Kuwahara; Y Miyamoto; M Ishikawa; Hamanaka, I; N Kajiyama; N Takahashi; O Nakagawa; Masuda, I; Kishimoto, I; K Nakao
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 32(5), 765-776, May 2000, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Gq及びgp130刺激の心筋再構築における異なる役割
    桑原 宏一郎; 斎藤 能彦; 石川 匡洋; 小川 惠美子; 原田 昌樹; 中尾 一和
    日本臨床分子医学会記録, 36, 40-40, Mar. 2000, Refereed, Not invited
  • Effect of interleukin-1 beta on cardiac hypertrophy and production of natriuretic peptides in rat cardiocyte culture
    E Harada; O Nakagawa; M Yoshimura; M Harada; M Nakagawa; Y Mizuno; Y Shimasaki; M Nakayama; H Yasue; K Kuwahara; Y Saito; K Nakao
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 31(11), 1997-2006, Nov. 1999, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro
    K Kuwahara; Y Saito; M Harada; M Ishikawa; E Ogawa; Y Miyamoto; Hamanaka, I; S Kamitani; N Kajiyama; N Takahashi; O Nakagawa; Masuda, I; K Nakao
    CIRCULATION, 100(10), 1116-1124, Sep. 1999, Refereed, Not invitedWebofScienceリポジトリ
  • The effects of the selective ROCK inhibitor, Y27632, on ET-1-induced hypertrophic response in neonatal rat cardiac myocytes - possible involvement of Rho ROCK pathway in cardiac muscle cell hypertrophy
    K Kuwahara; Y Saito; O Nakagawa; Kishimoto, I; M Harada; E Ogawa; Y Miyamoto; Hamanaka, I; N Kajiyama; N Takahashi; T Izumi; R Kawakami; N Tamura; Y Ogawa; K Nakao
    FEBS LETTERS, 452(3), 314-318, Jun. 1999, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • A heart-specific increase in cardiotrophin-1 gene expression precedes the establishment of ventricular hypertrophy in genetically hypertensive rats
    M Ishikawa; Y Saito; Y Miyamoto; M Harada; K Kuwahara; E Ogawa; O Nakagawa; Hamanaka, I; N Kajiyama; N Takahashi; Masuda, I; T Hashimoto; O Sakai; T Hosoya; K Nakao
    JOURNAL OF HYPERTENSION, 17(6), 807-816, Jun. 1999, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • フィブロネクチンのBNP遺伝子転写亢進機序の検討
    小川 惠美子; 斎藤 能彦; 原田 昌樹; 桑原 宏一郎; 宮本 恵宏; 浜中 一郎; 梶山 登; 井野邊 義人; 高橋 伸基; 和泉 武彦
    日本内分泌学会雑誌, 75(1), 111-111, Apr. 1999, Refereed, Not invitedリポジトリ
  • Cardiotrophin-1によるgp130刺激とCISファミリーの発現 生体内,特に新血管系での検討
    浜中 一郎; 斎藤 能彦; 岸本 一郎; 宮本 恵宏; 原田 昌樹; 桑原 宏一郎; 小川 惠美子; 梶山 登; 井野邊 義人; 和泉 武彦
    日本内分泌学会雑誌, 75(1), 199-199, Apr. 1999, Refereed, Not invitedリポジトリ
  • Restriction Landmark cDNA Scanning(RLCS)法を用いた,圧負荷肥大心と容量負荷肥大心に特異的なクローンの発見
    和泉 武彦; 斉藤 能彦; 石川 匡洋; 錦見 俊雄; 岸本 一郎; 宮本 恵宏; 原田 昌樹; 桑原 宏一郎; 小川 惠美子; 浜中 一郎
    日本内分泌学会雑誌, 75(1), 111-111, Apr. 1999, Refereed, Not invitedリポジトリ
  • G蛋白共役型受容体刺激による活性化ERKは5'隣接領域の遠位部を介してANP遺伝子を誘導する
    桑原 宏一郎; 斎藤 能彦; 岸本 一郎; 小川 佳宏; 田村 尚久; 原田 昌樹; 小川 惠美子; 宮本 恵宏; 浜中 一郎; 梶山 登
    Japanese Circulation Journal, 63(Suppl.I), 169-169, Mar. 1999, Refereed, Not invitedリポジトリ
  • アンジオテンシノーゲン遺伝子5'上流領域の遺伝子多型と本態性高血圧症との連関研究
    梶山 登; 斎藤 能彦; 宮本 恵宏; 岸本 一郎; 原田 昌樹; 桑原 宏一郎; 小川 惠美子; 浜中 一郎; 井野邉 義人; 和泉 武彦
    Japanese Circulation Journal, 63(Suppl.I), 215-215, Mar. 1999, Refereed, Not invitedリポジトリ
  • ラット心臓を用いたCardiotrophin-1投与によるgp130刺激とCISファミリーの発現についての検討
    浜中 一郎; 斎藤 能彦; 宮本 恵宏; 岸本 一郎; 原田 昌樹; 桑原 宏一郎; 小川 惠美子; 梶山 登; 高橋 伸基; 和泉 武彦
    Japanese Circulation Journal, 63(Suppl.I), 248-248, Mar. 1999, Refereed, Not invitedリポジトリ
  • 容量負荷型肥大心において特異的に発現亢進している新規遺伝子の発見 Restriction Landmark cDNA Scanning(RLCS)法を用いて
    和泉 武彦; 斎藤 能彦; 石川 匡洋; 桝田 出; 岸本 一郎; 宮本 恵宏; 井野邉 義人; 原田 昌樹; 桑原 宏一郎; 小川 惠美子
    Japanese Circulation Journal, 63(Suppl.I), 251-251, Mar. 1999, Refereed, Not invitedリポジトリ
  • フィブロネクチンのoutside-in signalingによるBNP遺伝子転写亢進機序の解明
    小川 惠美子; 斎藤 能彦; 桑原 宏一郎; 原田 昌樹; 高橋 伸基; 岸本 一郎; 宮本 恵宏; 井野邉 義人; 浜中 一郎; 梶山 登
    Japanese Circulation Journal, 63(Suppl.I), 252-252, Mar. 1999, Refereed, Not invitedリポジトリ
  • エンドセリン-1による心筋細胞肥大反応におけるRho/p160rock経路の関与
    桑原 宏一郎; 斎藤 能彦; 岸本 一郎; 小川 佳宏; 田村 尚久; 原田 昌樹; 小川 惠美子; 宮本 恵宏; 浜中 一郎; 梶山 登
    Japanese Circulation Journal, 63(Suppl.I), 642-642, Mar. 1999, Refereed, Not invitedリポジトリ
  • Endothelial nitric oxide synthase gene is positively associated with essential hypertension
    Y Miyamoto; Y Saito; N Kajiyama; M Yoshimura; Y Shimasaki; M Nakayama; S Kamitani; M Harada; M Ishikawa; K Kuwahara; E Ogawa; Hamanaka, I; N Takahashi; T Kaneshige; H Teraoka; T Akamizu; N Azuma; Y Yoshimasa; T Yoshimasa; H Itoh; Masuda, I; H Yasue; K Nakao
    HYPERTENSION, 32(1), 3-8, Jul. 1998, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Interaction of myocytes and nonmyocytes is necessary for mechanical stretch to induce ANP/BNP production in cardiocyte culture
    M Harada; Y Saito; K Kuwahara; E Ogawa; M Ishikawa; O Nakagawa; Y Miyamoto; S Kamitani; Hamanaka, I; N Kajiyama; N Takahashi; Masuda, I; H Itoh; K Nakao
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 31(SUPPL. 1), S357-S359, 1998, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Endothelin-1 and cardiotrophin-1 induce brain natriuretic peptide gene expression by distinct transcriptional mechanisms
    K Kuwahara; Y Saito; Y Ogawa; N Tamura; M Ishikawa; M Harada; E Ogawa; Y Miyamoto; Hamanaka, I; S Kamitani; N Kajiyama; N Takahashi; O Nakagawa; Masuda, I; K Nakao
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 31(SUPPL. 1), S354-S356, 1998, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy - Evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes
    M Harada; H Itoh; O Nakagawa; Y Ogawa; Y Miyamoto; K Kuwahara; E Ogawa; T Igaki; J Yamashita; Masuda, I; T Yoshimasa; Tanaka, I; Y Saito; K Nakao
    CIRCULATION, 96(10), 3737-3744, Nov. 1997, Refereed, Not invitedWebofScienceリポジトリ
  • Role of cardiac nonmyocytes in cyclic mechanical stretch-induced myocyte hypertrophy
    M Harada; Y Saito; O Nakagawa; Y Miyamoto; M Ishikawa; K Kuwahara; E Ogawa; M Nakayama; S Kamitani; Hamanaka, I; N Kajiyama; Masuda, I; H Itoh; Tanaka, I; K Nakao
    HEART AND VESSELS, 198-200, 1997, Refereed, Not invitedWebofScienceリポジトリ
  • cDNA cloning of rat cardiotrophin-1 (CT-1): Augmented expression of CT-1 gene in ventricle of genetically hypertensive rats
    M Ishikawa; Y Saito; Y Miyamoto; K Kuwahara; E Ogawa; O Nakagawa; M Harada; Masuda, I; K Nakao
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 219(2), 377-381, Feb. 1996, Refereed, Not invitedWebofScienceリポジトリ電子ジャーナル

MISC

  • Association of Mineralocorticoid Receptor Antagonist by Hospitalized Patients With Heart Failure With Preserved Ejection Fraction With Outcomes After Discharge
    Hidenori Yaku; Takao Kato; Takeshi Morimoto; Yasutaka Inuzuka; Yodo Tamaki; Erika Yamamoto; Yusuke Yoshikawa; Neiko Ozasa; Koichiro Kuwahara; Takeshi Kimura
    第23回日本心不全学会, Oct. 2019, Refereed, Not invited
  • BNP異常高値の原因がmacro-proBNP血症であった症例
    中川 靖章; 錦見 俊雄; 酒井 宏; 大野 聖子; 木下 秀之; 稲住 英明; 森内 健史; 柳澤 洋; 桑原 宏一郎; 堀江 稔; 木村 剛
    日本内分泌学会雑誌, 94(1), 347 - 347, Apr. 2018, Not invited
  • アドレノメデュリンは加齢や肥満に伴う高血圧を抑制する
    趙 晃済; 桑原 宏一郎; 錦見 俊雄; 中川 靖章; 木下 秀之; 南 丈也; 稲住 英明; 森内 健史; 大矢 未来; 南野 直人; 木村 剛; 寒川 賢治; 中尾 一和
    Anti-aging Science, 9(2), 100 - 100, Dec. 2017, Not invited
  • マクロproBNP血症の一例
    中川 靖章; 錦見 俊雄; 酒井 宏; 大野 聖子; 木下 秀之; 稲住 英明; 森内 健史; 桑原 宏一郎; 堀江 稔; 木村 剛
    日本内分泌学会雑誌, 93(4), 1392 - 1392, Dec. 2017, Not invited
  • 2-Year Natural History of Lower Limbs in Patients With End-stage Renal Disease on Hemodialysis Due to Diabetic Nephropathy; From PREDICT Study
    Tamon Kato; Yusuke Miyashita; Takashi Miura; Souitirou Ebisawa; Tatsuya Saigusa; Koichiro Kuwahara
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 70(18), B71 - B71, Oct. 2017, Not invitedWebofScienceリポジトリ
  • Endothelium-derived C-type natriuretic peptide regulates blood pressure through the maintenance of endothelial function
    K. Kuwahara; K. Nakao; T. Nishikimi; Y. Nakagawa; H. Kinoshita; T. Tokudome; N. Minamino; T. Kimura; K. Kangawa; K. Nakao
    EUROPEAN JOURNAL OF HEART FAILURE, 19, 596 - 596, May 2017, Not invitedWebofScienceリポジトリ
  • 脂肪由来のアドレノメデュリンは加齢および肥満に伴う血圧上昇を抑制する
    趙 晃済; 桑原 宏一郎; 南 丈也; 錦見 俊雄; 南野 直人; 中川 靖章; 木下 秀之; 稲住 英明; 森内 健史; 寒川 賢治; 中尾 一和; 木村 剛
    日本臨床分子医学会学術総会プログラム・抄録集, 54回, 72 - 72, Apr. 2017, Not invited
  • 脂肪細胞由来adrenomedullinは加齢および肥満に伴う血圧上昇を抑制する(Adipocyte-derived Adrenomedullin Suppresses Age- and Obesity-related Increase in Blood Pressure)
    趙 晃済; 桑原 宏一郎; 南 丈也; 錦見 俊雄; 南野 直人; 中川 靖章; 木下 秀之; 稲住 英明; 森内 健史; 小池 薫; 寒川 賢治; 中尾 一和; 木村 剛
    日本循環器学会学術集会抄録集, 81回, PJ - 322, Mar. 2017, Not invited
  • マクロproBNP血症の一例
    中川靖章; 錦見俊雄; 錦見俊雄; 酒井宏; 大野聖子; 木下秀之; 稲住英明; 森内健史; 桑原宏一郎; 堀江稔; 木村剛
    日本心血管内分泌代謝学会学術総会プログラム及び抄録集, 21st, 128, 2017, Not invited
    http://jglobal.jst.go.jp/public/201802210782294861リポジトリ
  • Brain Natriuretic Peptide Counteracting the Renin-angiotensin-aldosterone System in Accelerated Malignant Hypertension
    Hitoshi Nakagawa; Yuji Mizuno; Eisaku Harada; Yoshinobu Morikawa; Koichiro Kuwahara; Yoshihiko Saito; Hirofumi Yasue
    AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 352(5), 534 - 539, Nov. 2016, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Secretion of ProBNP is Regulated by Mir30-GALNTs Axis Dependent O-linked Glycosylation in the Pathological Myocardium
    Yasuaki Nakagawa; Koichiro Kuwahara; Toshio Nishikimi; Hideyuki Kinoshita; Hideki Inazumi; Kenji Moriuchi; Takao Kato; Naoto Minamino; Kazuwa Nacho; Takeshi Kimura
    CIRCULATION, 134, Nov. 2016, Not invitedWebofScienceリポジトリ
  • Characteristics of Diagnostic Modalities and Corticosteroid Therapy in Cardiac Sarcoidosis
    Yanagisawa H; Kinoshita H; Kato T; Saito N; Shizuta S; Nakagawa Y; Kuwahara K; Ono K; Kimura T
    心不全学会 2016, Oct. 2016, Refereed, Not invited
  • 肺動脈性肺高血圧症に対する肺移植術後急性期における左室および右室機能の評価
    米田智也; 木下秀之; 木下秀之; 中島康弘; 中島康弘; 本山秀樹; 土屋恭子; 青山晃博; 陳豊史; 中川靖章; 柳澤洋; 牧山武; 静田聡; 桑原宏一郎; 木村剛; 伊達洋至; 一山智
    日本心臓病学会学術集会(Web), 64th, ROMBUNNO.P‐366 (WEB ONLY) - 366, Sep. 2016, Not invited
    http://jglobal.jst.go.jp/public/201602274122812145リポジトリ
  • MiR30-GALNT1/2 axis-mediated O-glycosylation plays a critical role in the processing and secretion of pro-brain natriuretic peptide by failing myocardium
    Y. Nakagawa; T. Nishikimi; K. Kuwahara; S. Yasuno; H. Kinoshita; C. Yamada; H. Inazumi; T. Kato; Y. Kuwabara; K. Ueshima; K. Nakao; T. Kimura
    EUROPEAN HEART JOURNAL, 37, 409 - 409, Aug. 2016, Not invitedWebofScienceリポジトリ
  • 膠原病関連肺高血圧症とCT所見
    柳澤 洋; 木下 秀之; 吉藤 元; 半田 知宏; 藤井 隆夫; 牧山 武; 中川 靖章; 静田 聡; 桑原 宏一郎; 三森 経世; 木村 剛
    呼吸と循環, 64(5), S46 - S47, May 2016, Not invited
  • MiR30-GALNT1/2 axis-mediated glycosylation at threonine 48 and 71 plays an essential role in the increased secretion of unprocessed pro-brain natriuretic peptide by failing hearts
    K. Koichro Kuwahara; Y. Nakagawa; T. Nishikimi; K. Kangawa; N. Minamino; K. Nakao; T. Kimura
    EUROPEAN JOURNAL OF HEART FAILURE, 18, 273 - 273, May 2016, Not invitedWebofScienceリポジトリ
  • 糖尿病性腎症におけるN型Ca2+チャネル阻害の腎保護効果
    大野祥子; 横井秀基; 笠原正登; 森潔; 桑原宏一郎; 藤倉純二; 内藤雅喜; 桑原孝成; 菅原照; 柳田素子; 中尾一和; 向山政志
    日本内分泌学会雑誌, 92(1), 212, 01 Apr. 2016, Not invited
    http://jglobal.jst.go.jp/public/201602206101824521リポジトリ
  • Mir-30-GALNTs Axis-mediated Regulation in Glcosylation and Secretion of proBNP in the Failing Heart.
    Nakagawa Y; Kuwahara K; Minamino N; Kato T; Kinoshita H; Yamada C; Inazumi H; Nakao K; Kimura T
    第80回日本循環器学会学術集会, Mar. 2016, Refereed, Not invited
  • 肺血管拡張薬中止理由の検討と病棟専従薬剤師の役割の考察
    吉田優子; 木下秀之; 吉田詩織; 木下美津子; 中川靖章; 牧山武; 静田聡; 桑原宏一郎; 木村剛; 松原和夫
    呼吸と循環, 63(8), S55-S56 - S56, 15 Aug. 2015, Not invited
    http://jglobal.jst.go.jp/public/201502202267515583リポジトリ
  • 肺高血圧症合併肺ランゲルハンス細胞組織球症に対する治療経過
    柳澤洋; 木下秀之; 山田徹; 半田知宏; 中川靖章; 牧山武; 静田聡; 桑原宏一郎; 伊達洋至; 木村剛
    呼吸と循環, 63(8), S57 - S57, 15 Aug. 2015, Not invited
    http://jglobal.jst.go.jp/public/201502210376702647リポジトリ
  • 糖尿病性腎症におけるN型Ca2+チャネル阻害の腎保護効果
    大野 祥子; 横井 秀基; 笠原 正登; 森 潔; 桑原 宏一郎; 藤倉 純二; 内藤 雅喜; 桑原 孝成; 今牧 博貴; 石井 輝; 古賀 健一; 塩田 文彦; 沼田 朋大; 菅原 照; 森 泰生; 中尾 一和; 柳田 素子; 向山 政志
    日本腎臓学会誌, 57(3), 569 - 569, Apr. 2015, Not invited
  • Ion channel remodeling in the progression of heart failure
    Koichiro Kuwahara
    The 79th Annual Scientific Meeting of The Japanese Circulation Society, Apr. 2015, Not invited
  • TRPC6 in pathological cardiac remodeling
    Koichiro Kuwahara
    The 88th Annual Meeting of The Japanese Pharmacological Society, Mar. 2015, Not invited
  • 肺高血圧症を早期に発見できた間質性肺炎合併多発性筋炎の1症例
    脊古裕太; 木下秀之; 柳沢洋; 藤井隆夫; 半田知宏; 山田千夏; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛
    日本循環器学会近畿地方会(Web), 119th, KINKI119,E14 (WEB ONLY), 2015, Not invited
    http://jglobal.jst.go.jp/public/201502208166036259リポジトリ
  • ARVD様心形態を示した亜急性心筋炎の一例
    牧山武; 川路徹真; 小笹寧子; 静田聡; 桑原宏一郎; 的場芳樹; 高橋衛; 木村剛
    日本血管生物医学会学術集会プログラム・抄録集, 23rd, 190, 2015, Not invited
    http://jglobal.jst.go.jp/public/201602213719114769リポジトリ
  • 肺移植待機中の肺動脈性肺高血圧症患者における予後予測指標の検討
    山上新太郎; 木下秀之; 本山秀樹; 土屋恭子; 青山晃博; 陳豊史; 辻村郎; 柳澤洋; 山田千夏; 牧山武; 中川靖章; 靜田聡; 桑原宏一郎; 尾野亘; 伊達洋至; 木村剛
    日本循環器学会近畿地方会(Web), 120th, KINKI120,C39 (WEB ONLY), 2015, Not invited
    http://jglobal.jst.go.jp/public/201602228116050312リポジトリ
  • 非アルコール性脂肪肝炎に合併したと考えられる門脈圧亢進症性肺動脈性肺高血圧症の1症例
    辰島正二郎; 木下秀之; 柳沢洋; 川治徹真; 山田千夏; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛
    日本循環器学会近畿地方会(Web), 120th, KINKI120,C36 (WEB ONLY), 2015, Not invited
    http://jglobal.jst.go.jp/public/201602245485463134リポジトリ
  • 血液透析施行中の末期腎不全に合併した肺高血圧症に対し肺血管拡張薬を投与した1症例
    家村知樹; 山田千夏; 木下秀之; 辰島正二郎; 小笹寧子; 渡部宏俊; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛
    日本循環器学会近畿地方会(Web), 120th, KINKI120,F23 (WEB ONLY), 2015, Not invited
    http://jglobal.jst.go.jp/public/201602296482620208リポジトリ
  • 気腫合併肺線維症に合併した高度肺高血圧に対し肺血管拡張療法を行った1症例
    岡林真梨恵; 木下秀之; 相澤卓範; 半田知宏; 室繁郎; 山田千夏; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛
    日本循環器学会近畿地方会(Web), 120th, KINKI120,C37 (WEB ONLY), 2015, Not invited
    http://jglobal.jst.go.jp/public/201602296682654921リポジトリ
  • Role of O-glycosylation in N-terminal Region of Human proBNP in proBNP Processing
    Yasuaki Nakagawa; Toshio Nishikimi; Koichiro Kuwahara; Shinji Yasuno; Hideyuki Kinoshita; Yoshihiro Kuwabara; Chinatsu Yamada; Kenji Ueshima; Takeshi Kumura; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 20(10), S151 - S151, Oct. 2014, Not invitedWebofScienceリポジトリ
  • Pivotal Involvement of Renin-angiotensin System in Generating Arrhythmogenic Substrates in Mice with Chronic Heart Failure and Lethal Arrhythmias
    Chinatsu Yamada; Koichiro Kuwahara; Hideyuki Kinoshita; Yasuaki Nakagawa; Toshio Nishikimi; Kazuwa Nakao; Takeshi Kimura
    JOURNAL OF CARDIAC FAILURE, 20(10), S185 - S185, Oct. 2014, Not invitedWebofScienceリポジトリ
  • 肺動脈性肺高血圧症患者に対する最新の治療を考える
    木下秀之; 柳澤洋; 山田千夏; 中川靖章; 牧山武; 静田聡; 桑原宏一郎; 木村剛
    日本心臓病学会学術集会抄録(CD-ROM), 62nd, ROMBUNNO.JS4-3, 02 Sep. 2014, Not invited
    http://jglobal.jst.go.jp/public/201502293528713846リポジトリ
  • Critical involvement of renin-angiotensin system for developing arrhythmogenic remodeling in mice with chronic heart failure and lethal arrhythmias
    C. Yamada; K. Kuwahara; Y. Kuwabara; H. Kinoshita; Y. Nakagawa; T. Nihikimi; K. Nakao; T. Kimura
    EUROPEAN HEART JOURNAL, 35, 328 - 329, Sep. 2014, Not invitedWebofScienceリポジトリ
  • 第3回 重症肺高血圧症カンファレンス 症例提示‐3 肺野に異常陰影の出現を認めた特発性肺動脈性肺高血圧症の1症例
    木下秀之; 柳澤洋; 西川隆介; 中川靖章; 牧山武; 桑原宏一郎; 木村剛
    心臓, 46(6), 807 - 811, 15 Jun. 2014, Not invitedリポジトリ電子ジャーナル
  • 糖尿病性腎症におけるN型Ca2+チャネル阻害の意義
    大野 祥子; 横井 秀基; 笠原 正登; 森 潔; 桑原 宏一郎; 藤倉 純二; 内藤 雅喜; 桑原 孝成; 今牧 博貴; 石井 輝; 古賀 健一; 沼田 朋大; 菅原 照; 森 泰生; 柳田 素子; 中尾 一和; 向山 政志
    糖尿病, 57(Suppl.1), S - 266, Apr. 2014, Not invited
  • 血管肉腫による収縮性心膜炎様の病態をきたした1症例
    小椋淳平; 木下秀之; 川治徹真; 桑原佳宏; 中川靖章; 牧山武; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 117th, KINKI117,H17 (WEB ONLY), 2014, Not invited
    http://jglobal.jst.go.jp/public/201402251240490565リポジトリ
  • 先天性右肺動脈欠損を伴う肺高血圧症に僧帽弁逆流症・心房細動を合併し,集学的治療を施行した1例
    笹智樹; 桑原佳宏; 田崎淳一; 木下秀之; 牧山武; 中川靖章; 静田聡; 桑原宏一郎; 尾野亘; 木村剛
    日本循環器学会近畿地方会(Web), 117th, KINKI117,D09 (WEB ONLY), 2014, Not invited
    http://jglobal.jst.go.jp/public/201402278409536603リポジトリ
  • 間質性肺炎を合併した強皮症関連肺動脈性高血圧症に対しPGI2持続静注療法を施行した1症例
    柳澤洋; 木下秀之; 西川隆介; 桑原佳宏; 中川靖章; 牧山武; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 117th, KINKI117,G39 (WEB ONLY), 2014, Not invited
    http://jglobal.jst.go.jp/public/201402295619301031リポジトリ
  • サルコイドーシスに合併した肺高血圧症の一例
    沼尚吾; 木下秀之; 辰島正二郎; 樋上裕起; 牧山武; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 117th, KINKI117,G21 (WEB ONLY), 2014, Not invited
    http://jglobal.jst.go.jp/public/201402296994335012リポジトリ
  • 膠原病関連肺高血圧症に対する早期発見による肺血管拡張薬治療効果の検討
    柳澤洋; 木下秀之; 山田千夏; 桑原佳宏; 中川靖章; 牧山武; 静田聡; 尾野亘; 塩井哲雄; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 118th, KINKI118,A16 (WEB ONLY), 2014, Not invited
    http://jglobal.jst.go.jp/public/201502251055501264リポジトリ
  • Pivotal contribution of renin-angiotensin system to promoting arrhythmogenic remodeling in mice model of chronic heart failure with lethal arrhythmias
    Koichiro Kuwahara
    Gordon Conference: Angiotensin The Renin-Angiotensin System Beyond Angiotensin II, 2014, Not invited
  • O-glycosylated Pro-B-type Natriuretic Peptide is Cleaved Intracellularly by Furin in Ventricular and Atrial Myocytes: Importance of the Distance between the O-glycosylation and Cleavage Sites
    Toshio Nishikimi; Yasuaki Nakagawa; Naoto Minamino; Masashi Ikeda; Toshihiko Ishimitsu; Chinatsu Yamada; Kazuhiro Nakao; Yoshihiro Kuwabara; Hideyuki Kinoshita; Koichiro Kuwahara; Kenji Kangawa; Kazuwa Nakao
    CIRCULATION, 128(22), Nov. 2013, Not invitedWebofScienceリポジトリ
  • Evaluation of proBNP in End-stage Renal Disease Patients on Hemodialysis
    Yasuaki Nakagawa; Toshio Nishikimi; Koichiro Kuwahara; Shinji Yasuno; Hideyuki Kinoshita; Yoshihiro Kuwabara; Kazuhiro Nakao; Chinatsu Yamada; Kenji Ueshima; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 19(10), S168 - S168, Oct. 2013, Not invitedWebofScienceリポジトリ
  • N型Caチャネルノックアウトマウスを用いた糖尿病性腎症におけるN型カルシウムチャネルの意義
    大野 祥子; 横井 秀基; 笠原 正登; 森 潔; 桑原 宏一郎; 藤倉 純二; 内藤 雅喜; 桑原 孝成; 今牧 博貴; 古賀 健一; 沼田 朋大; 菅原 照; 森 泰生; 中尾 一和; 向山 政志
    日本高血圧学会総会プログラム・抄録集, 36回, 282 - 282, Oct. 2013, Not invited
  • SRF転写活性化因子MRTF-Aの脂肪組織形成における意義
    趙 晃済; 南 丈也; 桑原 宏一郎; 日下部 徹; 野口 倫生; 酒井 建; 錦見 俊雄; 中川 靖章; 木下 秀之; 桑原 佳宏; 山田 千夏; 柴田 純子; 山田 優子; 中尾 一泰; 上嶋 健治; 保野 慎治; 細田 公則; 小池 薫; 中尾 一和
    肥満研究, 19(Suppl.), 177 - 177, Sep. 2013, Not invited
  • Effect of hemodyalysis on precursor proBNP and glycosylated NT-proBNP in end-stage renal disease patients
    Y. Nakagawa; T. Nishikimi; K. Kuwahara; S. Yasuno; H. Kinoshita; Y. Kuwabara; C. Yamada; K. Nakao; K. Ueshima; K. Nakao
    EUROPEAN HEART JOURNAL, 34, 938 - 938, Aug. 2013, Not invitedWebofScienceリポジトリ
  • 糖尿病性腎症におけるN型カルシウムチャネルの意義
    大野 祥子; 向山 政志; 横井 秀基; 笠原 正登; 森 潔; 藤倉 純二; 桑原 宏一郎; 内藤 雅喜; 桑原 孝成; 今牧 博貴; 石井 輝; 古賀 健一; 沼田 朋大; 菅原 照; 森 泰生; 中尾 一和
    日本腎臓学会誌, 55(3), 349 - 349, Apr. 2013, Not invited
  • Isoproterenol-induced spontaneous action potentials in the cardiac myocytes of transgenic mouse overexpressing HCN2
    Kensuke Oshita; Sachiyo Igata; Yoshihiro Kuwabara; Koichiro Kuwahara; Kazuo Ushijima; Makoto Takano
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 63, S134 - S134, 2013, Not invitedWebofScienceリポジトリ
  • Hickmanカテーテル関連血流感染症に対し抗生剤ロック療法を行った1症例の検討
    廣田圭昭; 木下秀之; 山田千夏; 中尾一泰; 南丈也; 桑原佳宏; 保野慎治; 宇佐美覚; 中川靖章; 牧山武; 錦見俊雄; 上嶋健治; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 116th, KINKI116,C50 (WEB ONLY), 2013, Not invited
    http://jglobal.jst.go.jp/public/201402210957734371リポジトリ
  • 肺ランゲルハンス細胞組織球症に合併した肺高血圧症に対しエポプロステノールを使用した1症例
    波多腰桃子; 木下秀之; 西川隆介; 山田千夏; 中尾一泰; 南丈也; 桑原佳宏; 保野慎治; 宇佐美覚; 中川靖章; 牧山武; 錦見俊雄; 上嶋健治; 桑原宏一郎; 木村剛
    日本循環器学会近畿地方会(Web), 116th, KINKI116,E07 (WEB ONLY), 2013, Not invited
    http://jglobal.jst.go.jp/public/201402296805351550リポジトリ
  • ナトリウム利尿ペプチド発現制御機構解明による心血管病治療標的の同定
    桑原 宏一郎
    第17回日本心血管内分泌代謝学会総会, 2013, Not invited
  • Myocardin-related transcription factor-A plays a pivotal role in vascular remodeling
    Koichiro Kuwahara
    第45回 日本動脈硬化学会, 2013, Not invited
  • 心不全・突然死モデルマウスを用いた心不全の病態解明と新規治療標的の同定
    桑原 宏一郎
    第90回日本生理学会大会, 2013, Not invited
  • Multi-organ communication in sudden arrhythmic death accompanied with heart failure
    Koichiro Kuwahara
    The77th Annual Scientific Meeting of The Japanese Circulation, 2013, Not invited
  • Elucidation of molecular mechanisms underlying the regulation and action of cardiovascular hormones to find novel therapeutic targets for cardiovascular diseases
    Koichiro Kuwahara
    The77th Annual Scientific Meeting of The Japanese Circulation, 2013, Not invited
  • Direct Renin Inhibitor Strongly Prevents Ventricular Arrhythmogenic Remodeling and Sudden Cardiac Death in Mice with Dilated Cardiomyopathy
    Chinatsu Yamada; Koichiro Kuwahara; Hidevuki Kinoshita; Yoshihiro Kuwabara; Takeya Minami; Kazuhiro Nakao; Shinji Yasuno; Yasuaki Nakagawa; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION, 126(21), Nov. 2012, Not invitedWebofScienceリポジトリ
  • 我が国の内科領域のトランスレーショナルリサーチとEBM トランスレーショナルリサーチ 4)内分泌代謝内科学領域のトランスレーショナルリサーチ
    HOSODA KIMINORI; YASODA AKIHIRO; EBIHARA KEN; KUWAHARA KOICHIRO; MUKOYAMA MASASHI; NAKAO KAZUWA
    日本内科学会雑誌, 101(9), 2552 - 2562, 10 Sep. 2012, Not invitedリポジトリ電子ジャーナル
  • Direct renin inhibitor prevents ventricular remodeling and sudden arrhythmic death in mice with dilated cardiomyopathy
    C. Yamada; K. Kuwahara; T. Minami; Y. Kuwabara; K. Nakao; H. Kinoshita; S. Usami; Y. Nakagawa; T. Nishikimi; K. Nakao
    EUROPEAN HEART JOURNAL, 33, 1100 - 1100, Aug. 2012, Not invitedWebofScienceリポジトリ
  • 禁酒と減量により血糖コントロールが改善した肝硬変合併糖尿病の一例
    野村 英生; 清水 浩一郎; 桑原 宏一郎; 阿部 恵; 森 栄作; 日下部 徹; 藤倉 純二; 孫 徹; 海老原 健; 細田 公則; 中尾 一和
    日本内分泌学会雑誌, 88(1), 326 - 326, Apr. 2012, Not invited
  • トランスレーショナルリサーチ 4)内分泌代謝内科学領域のトランスレーショナルリサーチ
    HOSODA KIMINORI; YASODA AKIHIRO; EBIHARA KEN; KUWABARA KOICHIRO; MUKOYAMA MASASHI; NAKAO KAZUWA
    日本内科学会雑誌, 101, 115, 20 Feb. 2012, Not invitedリポジトリ電子ジャーナル
  • Calcium channels as novel therapeutic targets in heart failure
    Koichiro Kuwahara; Hideyuki Kinoshita; Kazuwa Nakao
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 118, 14P - 14P, 2012, Not invitedWebofScienceリポジトリ
  • Molecular mechanisms underlying cardioprotective effects of natriuretic peptide
    Koichiro Kuwahara
    The 7th Oulu Symposium, 2012, Not invited
  • Neurohumoral regulation in the process of pathological cardiac remodeling
    Koichiro Kuwahara
    第29回国際心臓研究学会(ISHR)日本部会, 2012, Not invited
  • Translational Research of Natriuretic Peptide in Cardiovascular Disease
    Koichiro Kuwahara
    The76th Annual Scientific Meeting of The Japanese CirculationSociety, 2012, Not invited
  • Induction of Myocardin-Related Transcription Factor-A Contributes to the Phenotypic Alteration of Vascular Smooth Muscle Cells and Plays a Pivotal Role in Vascular Remodeling
    Takeya Minami; Koichiro Kuwahara; Yasuaki Nakagawa; Hideyuki Kinoshita; Kazuhiro Nakao; Yoshihiro Kuwabara; Yuko Yamada; Chinatsu Yamada; Junko Shibata; Satoru Usami; Toshio Nishikimi; Kazuwa Nakao
    CIRCULATION, 124(21), Nov. 2011, Not invitedWebofScienceリポジトリ
  • Cardiac-Specific Overexpression of High Mobility Group Box 1 (HMGB1) Attenuates Cardiac Dysfunction Induced By Pressure Overload
    Akira Funayama; Tetsuro Shishido; Shunsuke Netsu; Mitsunori Ishino; Yoichiro Otaki; Shintaro Honda; Hiromasa Hasegawa; Shinpei Kadowaki; Taro Narumi; Satoshi Nishiyama; Hiroki Takahashi; Takanori Arimoto; Takehiko Miyashita; Takuya Miyamoto; Tetsu Watanabe; Chang-Hoon Woo; Jun-ichi Abe; Koichiro Kuwahara; Kazuwa Nakao; Yasuchika Takeishi; Isao Kubota
    CIRCULATION, 124(21), Nov. 2011, Not invitedWebofScienceリポジトリ
  • 心筋ミトゴンドリア機能を調節する転写調節ネットワーク(4.代謝制御からみた心筋障害・心不全の病態解明-基礎から臨床へ,<特集>第75回日本循環器学会学術集会)
    中川 靖章; 桑原 宏一郎; 中尾 一和
    循環器専門医 : 日本循環器学会専門医誌, 19(2), 243 - 248, 25 Sep. 2011リポジトリ
  • A Case of Severe Chronic Heart Failure Successfully Controlled with Long Term Administration of Tolvaptan; a V(2)-specific Vasopressin Receptor Antagonists
    Yuna Yamagami; Hideyuki Kinoshita; Koichiro Kuwahara; Yoshihiro Kuwabara; Shinji Yasuno; Satoru Usami; Yasuaki Nakagawa; Toshio Nishikimi; Kenji Ueshima; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 17(9), S166 - S166, Sep. 2011, Not invitedWebofScienceリポジトリ
  • HCN Channel Inhibition Prevents Sudden Arrhythmic Death in a Mouse Model of Dilated Cardiomyopathy Independently of Heart Rate Reduction
    Yoshihiro Kuwabara; Koichiro Kuwahara; Makoto Takano; Hideyuki Kinoshita; Yasuaki Nakagawa; Satoru Usami; Takeya Minami; Toshio Nishikimi; Kenji Ueshima; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 17(9), S153 - S153, Sep. 2011, Not invitedWebofScienceリポジトリ
  • HCN channel inhibition with ivabradine prevents sudden arrhythmic death in a mouse model of dilated cardiomyopathy
    Y. Kuwabara; K. Kuwahara; H. Kinoshita; M. Takano; Y. Nakagawa; S. Usami; S. Yasuno; T. Nishikimi; K. Ueshima; K. Nakao
    EUROPEAN HEART JOURNAL, 32, 288 - 289, Aug. 2011, Not invitedWebofScienceリポジトリ
  • Blockade of TRPC6/3 is a novel therapeutic approach for preventing pathological cardiac hypertrophy
    H. Kinoshita; K. Kuwahara; M. Nishida; H. Kurose; S. Kiyonaka; Y. Mori; Y. Kuwabara; Y. Nakagawa; K. Ueshima; K. Nakao
    EUROPEAN HEART JOURNAL, 32, 1093 - 1094, Aug. 2011, Not invitedWebofScienceリポジトリ
  • Analysis of circulating glycosylated N-terminal-proBNP and nonglycosylated N-terminal proBNP in patients with heart failure (HF) and chronic renal failure (CRF) on hemodialysis
    T. Nishikimi; M. Ikeda; Y. Takeda; T. Ishimitsu; N. Minamino; K. Kuwahara; Y. Nakagawa; H. Kinoshita; K. Nakao
    EUROPEAN HEART JOURNAL, 32, 910 - 910, Aug. 2011, Not invitedWebofScienceリポジトリ
  • BNP遺伝子発現調節領域におけるserum response factor応答領域の新たなる同定とその心筋細胞肥大反応における意義
    桑原 宏一郎
    第15回日本心血管内分泌学会, 2011, Not invited
  • 心房性および脳性ナトリウム利尿ペプチドの発現制御及び心不全発症における役割
    桑原 宏一郎
    第84回日本内分泌学会学術総会, 2011, Not invited
  • T-type Ca2+channel blockade improved cardiac autonomic nervous system imbalance and reduced sudden death in mice model of chronic heart failure
    H. Kinoshita; K. Kuwahara; T. Makoto; Y. Kuwabara; M. Fujiwara; S. Yasuno; S. Usami; Y. Nakagawa; K. Ueshima; K. Nakao
    EUROPEAN HEART JOURNAL, 31, 419 - 419, Sep. 2010, Not invitedWebofScienceリポジトリ
  • Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart
    Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Zhong Jian; Xianglu Rong; Shigeki Kiyonaka; Yoshihiro Kuwabara; Hitoshi Kurose; Ryuji Inoue; Yasuo Mori; Yuhao Li; Yasuaki Nakagawa; Satoru Usami; Masataka Fujiwara; Yuko Yamada; Takeya Minami; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION RESEARCH, 106(12), 1849 - U153, Jun. 2010, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart
    Hideyuki Kinoshita; Koichiro Kuwahara; Motohiro Nishida; Zhong Jian; Xianglu Rong; Shigeki Kiyonaka; Yoshihiro Kuwabara; Hitoshi Kurose; Ryuji Inoue; Yasuo Mori; Yuhao Li; Yasuaki Nakagawa; Satoru Usami; Masataka Fujiwara; Yuko Yamada; Takeya Minami; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION RESEARCH, 106(12), 1849 - U153, Jun. 2010, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Effusive constrictive periarditis possibly caused by infection in a patient with hyperthyroidism
    Chinatsu Yamada; Koichiro Kuwahara; Masako Miura; Yuko Yamada; Takeya Minami; Yoshihiro Kuwabara; Masataka Fujiwara; Hideyuki Kinoshita; Satoru Usami; Yasuaki Nakagawa; Kazuma Nakao
    ENDOCRINE JOURNAL, 57, S558 - S558, Mar. 2010, Not invitedWebofScienceリポジトリ
  • N-type Ca2+ channel blockade prevents sudden death in mice with heart failure
    Yuko Yamada; Koichiro Kuwahara; Hideyuki Kinoshita; Yoshihiro Kuwabara; Yasuaki Nakagawa; Masaki Harada; Shinji Yasuno; Takeya Minami; Satoshi Usami; Masataka Fujiwara; Masao Murakami; Kenji Ueshima; Kazuwa Nakao
    ENDOCRINE JOURNAL, 57, S566 - S566, Mar. 2010, Not invitedWebofScienceリポジトリ
  • Myocardin-related transcription factor-A, a Rho-dependent co-factor of serum response factor, is a common mediator for mechanical stretch- and neurohumoral stimulation-induced increase in BNP gene transcription
    Koichiro Kuwahara; Yoshihiro Kuwabara; Hideyuki Kinoshita; Kazuwa Nakao
    ENDOCRINE JOURNAL, 57, S549 - S550, Mar. 2010, Not invitedWebofScienceリポジトリ
  • Functional inhibition of p300 affects the mitochondrial function and cell survival in the post-natal heart in mice
    Yasuaki Nakagawa; Koichiro Kuwahara; Genzo Takemura; Masaharu Akao; Yuji Arai; Masaki Harada; Satoru Usami; Shinji Yasuno; Hideyuki Kinoshita; Masataka Fujiwara; Yoshihiro Kuwabara; Takeya Minami; Chinatsu Yamada; Kenji Ueshima; Kazuwa Nakao
    ENDOCRINE JOURNAL, 57, S566 - S567, Mar. 2010, Not invitedWebofScienceリポジトリ
  • CT dinucleotide repeat polymorphism in the promoter region of Guanylyl Cyclase (GC)-A gene is associated with essential hypertension in the Japanese
    Satoru Usami; Ichiro Kishimoto; Koichiro Kuwahara; Yasuaki Nakagawa; Shinji Yasuno; Hideyuki Kinoshita; Kazuwa Nakao
    ENDOCRINE JOURNAL, 57, S565 - S565, Mar. 2010, Not invitedWebofScienceリポジトリ
  • Search for novel therapeutic targets in heart failure
    Koichiro Kuwahara; Kazuwa Nakao
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 112, 18P - 18P, 2010, Not invitedWebofScienceリポジトリ
  • NRSF maintains normal cardiac structure and function
    Koichiro Kuwahara
    20th World Congress of the International Society of Heart Research, 2010, Not invited
  • Angiotensin receptors signaling in cardiac remodeling
    Koichiro Kuwahara
    14th International Congress of Endocrinology ICE2010, 2010, Not invited
  • Rho依存性転写共役因子myocardin-related transcription factor-Aの心肥大シグナルにおける役割
    桑原 宏一郎
    第33回 日本高血圧学会総会, 2010, Not invited
  • Rho and actin dynamics-dependent nuclear translocation of MRTF-A is a common molecular mechanisms underlying both mechanical stretch- and neurohumoral stimulation-induced cardiac hypertrophy
    Koichiro Kuwahara
    14th Annual Scientific Session of the Society of Cardiovacular Endocrinology and Metabolism, 2010, Not invited
  • 心房性および脳性ナトリウム利尿ペプチドの遺伝子発現調節、作用機序と臨床的意義の解明
    桑原 宏一郎
    第83回日本内分泌学会学術総会, 2010, Not invited
  • 心不全に対する新規治療標的の探索
    桑原 宏一郎
    第83回日本薬理学会年会, 2010, Not invited
  • Myocardin-related transcription factor-A is a common mediator of mechanical stretch- and neurohumoral stimulation-induced hypertrophic response
    Koichiro Kuwahara
    The74th Annual Scientific Meeting of The Japanese Circulation, 2010, Not invited
  • P300 Determines Tolerance to Ischemia in the Heart by Regulating Mitochondrial Gene Expression and Function
    Yasuaki Nakagawa; Koichiro Kuwahara; Masaki Harada; Satoru Usami; Shinji Yasuno; Hideyuki Kinoshita; Masataka Fujiwara; Yoshihiro Kuwabara; Yuko Yamada; Takeya Minami; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION RESEARCH, 105(7), E21 - E21, Sep. 2009, Not invitedWebofScienceリポジトリ
  • OE-172 A Novel NRSF-binding Partner Zfp90 Negatively Regulates the Repression Activity of NRSF, a Critical Regulator of Cardiac Fetal Gene Program(OE29,Molecular Biology Myocardium (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
    Kuwahara Koichiro; Murakami Masao; Harada Masaki; Nakagawa Yasuaki; Usami Satoru; Kinoshita Hideyuki; Yasuno Shinji; Fujiwara Masataka; Kuwabara Yoshihiro; Ueshima Kenji; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 73, 216 - 216, 01 Mar. 2009リポジトリ
  • PE-165 An Important Role of p300 on Mitochondrial Gene Expression and Function and Tolerance to Ischemia in the Heart(PE028,Heart Failure, Basic (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
    Nakagawa Yasuaki; Kuwahara Koichiro; Akao Masaharu; Katoh Masashi; Takemura Genzou; Harada Masaki; Usami Satoru; Yasuno Shinji; Kinoshita Hideyuki; Fujiwara Masataka; Kuwabara Yoshihiro; Ueshima Kenji; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 73, 440 - 440, 01 Mar. 2009リポジトリ
  • DPE-007 Protein Kinase G-mediated Inhibition of TRPC6 Channel Activity Participates in Anti-hypertrophic Effect of Cardiac Natriuretic Peptides(DPE02,Heart Failure, Basic (M),Digital Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
    Kinoshita Hideyuki; Kuwahara Koichiro; Inoue Ryuji; Nishida Motohiro; Kurose Hitoshi; Kiyonaka Shigeki; Mori Yasuo; Li Yuhao; Rong Xiang Lu; Murakami Masao; Nakagawa Yasuaki; Yasuno Shinji; Usami Satoru; Fujiwara Masataka; Kuwabara Yoshihiro; Yamada Yuko; Minami Takeshi; Harada Masaki; Ueshima Kenji; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 73, 357 - 357, 01 Mar. 2009リポジトリ
  • FRS-094 MRTF-A, a Rho-dependent Co-activaotr of SRF, Mediates Mechanical Stress-induced Hypertrophic Gene Reprogramming(FRS19,Genetic Abnormalities in Cardiac Hypertrophy and Cardiomyopathy (M),Featured Research Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
    Kuwahara Koichiro; Nakao Kazuwa; Olson Eric
    Circulation journal : official journal of the Japanese Circulation Society, 73, 162 - 162, 01 Mar. 2009リポジトリ
  • DIRECTLY REGULATES THE TRANSCRIPTION OF HCN4, CARDIAC PACEMAKER CHANNEL
    Makoto Takano; Kuniko Shimazaki; Shin-ichi Muramatsu; Koichiro Kuwahara
    JOURNAL OF PHYSIOLOGICAL SCIENCES, 59, 170 - 170, 2009, Not invitedWebofScienceリポジトリ
  • Transcriptional Pathways Regulating Cardiac Remodeling
    Koichiro Kuwahara
    2009MRC international Symposia, 2009, Not invited
  • 心房性および脳性ナトリウム利尿ペプチドの遺伝子発現調節、作用機序と臨床的意義の解明
    桑原 宏一郎
    第13回日本心血管内分泌代謝学会総会, 2009, Not invited
  • 心臓内分泌代謝機能における転写共役因子の役割
    桑原 宏一郎
    第82回日本内分泌学会学術総会, 2009, Not invited
  • MRTF-A, a Rho-dependent Co-activaotr of SRF, Mediates
    Koichiro Kuwahara
    The73rd Annual Scientific Meeting of The Japanese Circulation, 2009, Not invited
  • A Novel NRSF-binding Partner Zfp90 Negatively Regulates
    Koichiro Kuwahara
    The73rd Annual Scientific Meeting of The Japanese Circulation, 2009, Not invited
  • NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes
    倉富 忍; 倉富 暁子; 桑原 宏一郎; 石井 孝弘; 中尾 一和; 斉藤 能彦; 鷹野 誠
    心電図 = Electrocardiology, 28(5), 430 - 430, 03 Oct. 2008リポジトリ
  • Identification Of A New NRSF-binding Partner, Zfp90, Which Negatively Regulates The Repression Activity Of NRSF, A Critical Transcriptional Regulator Of Cardiac Fetal Gene Program
    Masao Murakami; Koichiro Kuwahara; Masaki Harada; Yasuaki Nakagawa; Satoru Usami; Hideyuki Kinoshita; Shinji Yasuno; Masataka Fujiwara; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION, 118(18), S332 - S333, Oct. 2008, Not invitedWebofScienceリポジトリ
  • MIRTF-A, a rho-dependent co-activator of SRF, mediates mechanical stress-induced hypertrophic gene activation
    Koichiro Kuwahara; Kazuwa Nakao; Eric Olson
    JOURNAL OF CARDIAC FAILURE, 14(7), S169 - S170, Sep. 2008, Not invitedWebofScienceリポジトリ
  • Blockade of T-Type Ca2+ Channel Corrects Imbalance in Cardiac Autonomic Nerve Activity and Prevents Sudden Arrhythmic Death in Chronic Heart Failure in Mice
    Hideyuki Kinoshita; Koichiro Kuwahara; Shinji Yasuno; Masao Murakami; Yasuaki Nakagawa; Satoru Usami; Masataka Fujiwara; Yoshihiro Kuwabara; Kenji Ueshima; Masaki Harada; Kazuwa Nakao
    CIRCULATION RESEARCH, 103(5), E36 - E36, Aug. 2008, Not invitedWebofScienceリポジトリ
  • FRS-007 Functional inhibition of p300 in the post-natal heart leads to mitochondrial dysfunction and cell death in mice(Novel Pathophysiological Mechanisms of Heart Failure(M),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
    Nakagawa Yasuaki; Kuwahara Koichiro; Akao Masaharu; Katoh Masashi; Takemura Genzou; Takano Makoto; Harada Masaki; Murakami Masao; Nakanishi Michio; Usami Satoru; Yasuno Shinji; Kinoshita Hideyuki; Fujiwara Masataka; Kuwabara Yoshihiro; Ueshima Kenji; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 72, 141 - 141, 01 Mar. 2008リポジトリ
  • 1 Protective Effects of Natriuretic Peptide System in Pathological Cardiac Remodeling(Peptide Hormones in Cardiovascular Diseases,Topic 4 (TP-4) (H),Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
    Kuwahara Koichiro; Harada Masaki; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 72, 89 - 89, 01 Mar. 2008リポジトリ
  • Functional inhibition of p300 leads to mitochondrial dysfunction and autophagic myocardial cell death in the adult heart
    Yasuaki Nakagawa; Koichiro Kuwahara; Genzo Takemura; Masaharu Alkao; Yuji Arai; Makoto Takano; Masaki Harada; Masao Murakami; Michio Nakanishi; Satoru Usami; Shinji Yasuno; Hideyuki Kinoshita; Masataka Fujiwara; Kenji Ueshima; Kazuwa Nakao
    CIRCULATION, 116(16), 196 - 196, Oct. 2007, Not invitedWebofScienceリポジトリ
  • PE-441 Essential Role of p300 in Post-natal Cardiac Mitochondrial Gene Expression and Maintenance of Normal Cardiac Function(Heart failure, basic-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
    Nakagawa Yasuaki; Kuwahara Koichiro; Harada Masaki; Takemura Genzou; Akao Masaharu; Takano Makoto; Nakanishi Michio; Usami Satoru; Yasuno Shinji; Kinoshita Hideyuki; Fujiwara Masataka; Ueshima Kenji; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 71, 435 - 435, 01 Mar. 2007リポジトリ
  • PE-305 The actin-binding Protein STARS is a Cytoskeletal Intermediary between MEF2 and SRF during Cardiac Remodeling(Cardiomyopathy, basic/clinical-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
    Kuwahara Koichiro; Nakao Kazuwa; Olson Eric
    Circulation journal : official journal of the Japanese Circulation Society, 71, 401 - 401, 01 Mar. 2007リポジトリ
  • PE-210 TRPC6 Fulfills a Calcineurin Signaling Circuit During Pathological Cardiac Remodeling(Cardiac hypertrophy, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
    Kuwahara Koichiro; Nakao Kazuwa; Olson Eric
    Circulation journal : official journal of the Japanese Circulation Society, 71, 377 - 377, 01 Mar. 2007リポジトリ
  • 第21回犬山不整脈カンファランスメインテーマ不整脈の成因と治療戦略テーマI「不整脈の新しい分子メカニズム」:心臓イオンチャネル遺伝子の転写制御機構~エピジェネティックスと機能分化~
    鷹野 誠; 倉富 忍; 堀江 稔; 斉藤 能彦; 桑原 宏一郎
    心電図, 27(3), 15 - 28, 2007, Not invitedリポジトリ
  • A role of p300 in post-natal cardiac mitochondrial gene expression and function
    Yasuaki Nakagawa; Koichiro Kuwahara; Masaki Harada; Genzo Takemura; Masaharu Akao; Michio Nakanishi; Satoru Usami; Hideyuki Kinoshita; Kennji Ueshima; Kazuwa Nakao
    JOURNAL OF CARDIAC FAILURE, 12(8), S162 - S162, Oct. 2006, Not invitedWebofScienceリポジトリ
  • TRPC6 forms a positive regulatory loop of calcineurin-NFAT pathway during cardiac remodeling
    Koichiro Kuwahara; Eric N. Olson
    CIRCULATION RESEARCH, 99(5), E28 - E28, Sep. 2006, Not invitedWebofScienceリポジトリ
  • OJ-021 Blockade of T-type Calcium Channel Reduced the Arrythmogenicity in the Dominant Negative NRSF Transgenic Mice(Heart failure, basic-2 (M) OJ4,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
    Kinoshita Hideyuki; Kuwahara Koichiro; Harada Masaki; Nakagawa Yasuaki; Kawakami Rika; Nakanishi Michio; Yasuno Shinji; Usami Satoru; Fujiwara Masataka; Takano Makoto; Horie Minoru; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 70, 239 - 239, 01 Mar. 2006リポジトリ
  • PJ-721 Physiological Remodeling of Cardiac Myocytes Induced by the Suppression of Neuron Restrictive Silencing Factor(Arrhythmia, basic-6 (A) PJ121,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
    Takano Makoto; Kuratomi Shinobu; Kinoshita Hideyuki; Yasuno Shinji; Nakao Kazuwa; Saitou Yoshihiko; Kuwahara Koichiro
    Circulation journal : official journal of the Japanese Circulation Society, 70, 667 - 667, 01 Mar. 2006リポジトリ
  • Role of the renin-angiotensin system (RAS) inhibition in chronic aortic regurgitation (AR) using angiotensin II type1a receptor knockout mice
    M Nakanishi; M Harada; K Kuwahara; R Kawakami; Y Nakagawa; S Yasuno; S Usami; H Kinoshita; Kishimoto, I; K Nakao
    JOURNAL OF CARDIAC FAILURE, 11(9), S318 - S318, Dec. 2005, Not invitedWebofScienceリポジトリ
  • Transcriptional Regulation of the Pacemaker Channel HCN4 (Excitation-contraction Coupling/Ion Channel 2 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
    Takano Makoto; Kuratomi Shinobu; Kuwahara Koichiro; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 69, 589 - 589, 01 Mar. 2005リポジトリ
  • NRSE-NRSF regulates the transcription of fetal type cardiac ion channels
    M Takano; K Kuwahara; Y Saito; K Nakao
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 97, 31P - 31P, 2005, Not invitedWebofScienceリポジトリ
  • Genetic disruption of angiotensin II type1a receptor in mice attenuates volume overload cardiomyopathy and improves survival in chronic aortic regurgitation
    M Nakanishi; Kishimoto, I; M Harada; K Kuwahara; R Kawakami; Y Nakagawa; K Tanimoto; S Yasuno; S Usami; H Kinoshita; K Nakao
    CIRCULATION, 110(17), 201 - 202, Oct. 2004, Not invitedWebofScienceリポジトリ
  • OJ-481 Beneficial Effects of Brain Natriuretic Peptide Overexpression in Cardiac Remodeling after Myocardial Infarction in Mice(Old Myocardial Infarction/Remodeling 1 (IHD) : OJ59)(Oral Presentation (Japanese))
    Kawakami Rika; Harada Masaki; Kuwahara Koichiro; Nakanishi Michio; Nakagawa Yasuaki; Yasuno Shinji; Usami Satoru; Kishimoto Ichirou; Saitou Yoshihiko; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 68, 347 - 347, 01 Mar. 2004リポジトリ
  • PJ-622 Significance of a novel interaction between NRSF and classII HDAC involved in the induction of ANP gene expression by Endothelin-1(Cardiac Hypertrophy, Basic and Clinical 2 (M) : PJ104)(Poster Session (Japanese))
    Nakagawa Yasuaki; Kuwahara Koichiro; Harada Masaki; Kawakami Rika; Nakanishi Michio; Tanimoto Keiji; Yasuno Shinji; Usami Satoru; Kinoshita Hideyuki; Saitou Yoshihiko; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 68, 632 - 632, 01 Mar. 2004リポジトリ
  • OE-006 The beneficial effects of natriuretic peptides following myocardial infarction are mediated partly by suppression of the renin-angiotensin system(Acute Myocardial Infarction, Basic 1 (IHD) : OE1)(Oral Presentation (English))
    Nakanishi Michio; Kishimoto Ichirou; Harada Masaki; Kuwahara Koichiro; Kawakami Rika; Nakagawa Yasuaki; Yasuno Shinji; Usami Satoru; Kinoshita Hideyuki; Saitou Yoshihiko; Nakao Kazuwa; Fukamizu Akiyoshi
    Circulation journal : official journal of the Japanese Circulation Society, 68, 143 - 143, 01 Mar. 2004リポジトリ
  • Relationship between Plasma Level of Cardiotrophin-1 and Prognosis in Patients with Dilated Cardiomyopathy
    Tsutamoto Takayoshi; Wada Atsuyuki; Ohnishi Masato; Tsutsui Takashi; Ohno Keijin; Ishii Chitose; Asai Shigeru; Kuwahara Koichiro; Nakao Kazuwa; Saitou Yoshihiko; Horie Minoru
    Circulation journal : official journal of the Japanese Circulation Society, 67, 95 - 95, 01 Mar. 2003リポジトリ
  • Angiotensin II Type 1 Receptor Improves the Arrhythmia Morbidityin Mice with Left Ventricular Hypertrophy
    Zhang Cuntai; Yasuno Shinji; Kuwahara Koichiro; Horie Minoru
    Circulation journal : official journal of the Japanese Circulation Society, 67, 233 - 233, 01 Mar. 2003リポジトリ
  • Role of Renin-Anglotensin System in Cardiac Remodeling after Aortic Regurgitation in Mice
    Nakanishi Michio; Harada Masaki; Kuwahara Koichiro; Takahashi Nobuki; Kawakami Rika; Nakagawa Yasuaki; Tanimoto Keiji; Yasuno Shinji; Usami Satoru; Saitoh Yoshitomo; Kinoshita Hideyuki; Nakao Kazuwa; Kishimoto Ichirou; Saitou Yoshihiko; Fukamizu Akiyoshi
    Circulation journal : official journal of the Japanese Circulation Society, 67, 226 - 226, 01 Mar. 2003リポジトリ
  • ERK5 Plays a Critical Role in Cardiotrophin-1-Induced Hypertrophy of Neonatal Rat Ventricular Myocytes
    Takahashi Nobuki; Saito Yoshihiko; Kuwahara Koichiro; Harada Masaki; Kawakami Rika; Nakagawa Yasuaki; Nakanishi Michio; Tanimoto Keiji; Yasuno Shinji; Usami Satoru; Saito Yoshitomo; Kinoshita Hideyuki; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 67, 224 - 225, 01 Mar. 2003リポジトリ
  • Evidence for Cardiac Myocyte Regeneration in Injured Myocardium by Bone Marrow Derived Cells
    Harada Masaki; Saitou Yoshihiko; Nakagawa Yasuaki; Adachi Yuichiro; Kuwahara Koichiro; Takahashi Nobuki; Kawakami Rika; Nakanishi Michio; Tanimoto Keiji; Li Yuhao; Yasuno Shinji; Usami Satoru; Saitoh Yoshitomo; Kinoshita Hideyuki; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 67, 191 - 191, 01 Mar. 2003リポジトリ
  • NRSF Is Involved in Molecular Pathways for Sudden Death Associated with Heart Failure
    Kuwahara Koichiro; Saitou Yoshihiko; Arai Yuji; Morisaki Takayuki; Nakagawa Yasuaki; Yasuno Shinji; Horie Minoru; Takano Makoto; Noma Akinori; Miyamoto Yoshihiro; Takemura Gennzou; Fujiwara Hisayoshi; Harada Masaki; Kawakami Rika; Nakanishi Michio; Usami Satoru; Saitoh Yoshitomo; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 67, 154 - 154, 01 Mar. 2003リポジトリ
  • In-Vivo Electrophysiological Study in Dominant-Negative NRSF Transgenic Mice : Ventricular Arrhythmia Vulnerability and Sudden Cardiac Death
    Yasuno Shinji; Saitou Yoshihiko; Horie Minoru; Takano Makoto; Noma Akinori; Arai Yuji; Kuwahara Koichiro; Takahashi Nobuki; Nakagawa Yasuaki; Harada Masaki; Kawakami Rika; Nakanishi Michio; Tanimoto Keiji; Usami Satoru; Saitoh Yoshitomo; Morisaki Takayuki; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 67, 344 - 344, 01 Mar. 2003リポジトリ
  • Disruption of natriuretic peptide receptor-A leads to higher mortality and exaggerated left ventricular remodeling after myocardial infarction in mice
    M Nakanishi; Kishimoto, I; M Harada; K Kuwahara; N Takahashi; R Kawakami; Y Nakagawa; K Tanimoto; Y Adachi; S Yasuno; S Usami; Y Saito; K Nakao; Y Saito
    CIRCULATION, 106(19), 148 - 148, Nov. 2002, Not invitedWebofScienceリポジトリ
  • The roles of angiotensin II type 2 (AT2) receptor on acute heart failure and long-term remodeling after myocardial infarction in mice
    Y Adachi; Y Saito; Kishimoto, I; M Harada; K Kuwahara; N Takahashi; R Kawakami; M Nakanishi; Y Nakagawa; K Tanimoto; Y Saitoh; S Yasuno; S Usami; K Nakao
    CIRCULATION, 106(19), 133 - 134, Nov. 2002, Not invitedWebofScienceリポジトリ
  • Neuron-restrictive silencer element is involved in the selective induction of cardiac embryonic genes expression by inhibition of histone deacetylase in cultured ventricular myocytes
    K Kuwahara; M Harada; N Takahashi; R Kawakami; Y Nakagawa; M Nakanishi; S Yasuno; S Usami; T Saitoh; K Tanimoto; Y Adachi; K Nakao
    CIRCULATION, 106(19), 5 - 5, Nov. 2002, Not invitedWebofScienceリポジトリ
  • A novel interaction between NRSF and class IIHDAC mediates CaMK signals in ET-1-induced ANP gene expression
    Y Nakagawa; Y Saito; K Kuwahara; M Harada; N Takahashi; R Kawakami; M Nakanishi; K Tanimoto; Y Adachi; S Yasuno; S Usami; Y Saito; K Nakao
    CIRCULATION, 106(19), 107 - 107, Nov. 2002, Not invitedWebofScienceリポジトリ
  • SOCS1 and SOCS3 inhibit hypertrophic responses to cardiotrophin-1 through inhibition of MEK5-ERK5 pathway independent of STAT3 suppression in neonatal rat ventricular myocytes
    N Takahashi; Y Saito; K Kuwahara; M Harada; R Kawakami; Y Nakagawa; M Nakanishi; K Tanimoto; S Yasuno; S Usami; Y Saito; K Nakao
    CIRCULATION, 106(19), 259 - 260, Nov. 2002, Not invitedWebofScienceリポジトリ
  • Relationship between plasma cardiotrophin-1 and left ventricular remodeling in patients with first acute myocardial infarction
    Hayashi Masaru; Tsutamoto Takayoshi; Maeda Keiko; Mabuchi Naoko; Tsutsui Takashi; Kinoshita Masahiko; Saitou Yoshihiko; Kuwahara Koichiro; Asai Shigeru
    Circulation journal : official journal of the Japanese Circulation Society, 66, 475 - 475, 31 Mar. 2002リポジトリ
  • Relationship between plasma level of cardiotrophin-1 and left ventricular mass index in patients with dilated cardiomyopathy
    Tsutamoto Takayoshi; Maeda Keiko; Hayashi Masaru; Tsutsui Takashi; Wada Atsuyuki; Ohnishi Masato; Fujii Masanori; Matsumoto Takehiro; Yamamoto Takashi; Takayama Tomoyuki; Kinoshita Masahiko; Saito Yoshihiko; Kuwahara Koichiro; Nakao Kazuwa; Asai Shigeru
    Circulation journal : official journal of the Japanese Circulation Society, 66, 391 - 391, 31 Mar. 2002リポジトリ
  • Overxepression of brain natriuretic peptide mediates cardiac matrix metalloproteinase induction and induces cardiac rupture after acute myocardial infarction in mice
    Kawakami Rika; Saitou Yoshihiko; Harada Masaki; Kuwahara Koichiro; Takahashi Nobuki; Li Yuhao; Nakagawa Yasuaki; Nakanishi Michio; Adachi Yuichiro; Tanimoto Keiji; Usami Satoru; Saitoh Yoshitomo; Yasuno Shinji; Nakao Kazuwa; Kishimoto Ichirou
    Circulation journal : official journal of the Japanese Circulation Society, 66, 434 - 434, 31 Mar. 2002リポジトリ
  • JAB/SOCS1 and CIS3/SOCS3 inhibit hypertrophic response to cardiotrophin-1 independent of STAT3 suppression in neonatal rat ventricular myocytes
    Takahashi Nobuki; Saito Yoshihiko; Hamanaka Ichiro; Kuwahara Koichiro; Harada Masaki; Kawakami Rika; Nakagawa Yasuaki; Nakanishi Michio; Tanimoto Keiji; Li Yuhao; Nakao Kazuwa; Hanakawa Yasushi; Yasukawa Hideo; Yoshimura Akihiko
    Circulation journal : official journal of the Japanese Circulation Society, 66, 445 - 445, 31 Mar. 2002リポジトリ
  • Possible involvement of Atypical Protein Kinase C in Aldosterone-induced-Angiotensin-Converting-Enzyme Gene Expression in Cultured Neonatal Rat Cardiocytes
    Harada Eisaku; Yoshimura Michihiro; Nakagawa Osamu; Nakagawa Masayo; Nakayama Masafumi; Shimasaki Yukio; Itoh Teruhiko; Nakamura Shota; Ogawa Hisao; Yasue Hirofumi; Mizuno Yuji; Harada Masaki; Kuwahara Koichiro; Saitou Yoshihiko; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 66, 618 - 618, 31 Mar. 2002リポジトリ
  • Inhibition of histone deacetylase selectively induces expression of cardiac embryonic genes that contain neuron-restrictive silencer element in cultured ventricular myocytes
    Kuwahara Koichiro; Saitou Yoshihiko; Takahashi Nobuki; Nakagawa Yasuaki; Harada Masaki; Kawakami Rika; Nakanishi Michio; Li Yuhao; Tanimoto Keiji; Yasuno Shinji; Usami Satoru; Saitoh Yoshitomo; Adachi Yuichiro; Nakao Kazuwa
    Circulation journal : official journal of the Japanese Circulation Society, 66, 265 - 265, 31 Mar. 2002リポジトリ
  • Genetic disruption of angiotensin II type 2 (AT2) receptor worsened short-term survival after acute myocardial infarction in mice
    Adachi Yuichiro; Saito Yoshihiko; Harada Masaki; Kuwahara Koichiro; Takahashi Nobuki; Kawakami Rika; Li Yuhao; Nakanishi Michio; Nakagawa Yasuaki; Tanimoto Keiji; Saitoh Yoshitomo; Yasuno Shinji; Usami Satoru; Nakao Kazuwa; Iwai Masaru; Horiuchi Masatsugu; Kishimoto Ichiro
    Circulation journal : official journal of the Japanese Circulation Society, 66, 196 - 196, 31 Mar. 2002リポジトリ
  • Disruption of natriuretic peptides receptor A leads to higher mortality and exaggerated left ventricular remodeling after myocardial infarction in mice
    Nakanishi Michio; Saitou Yoshihiko; Harada Masaki; Kuwahara Koichiro; Takahashi Nobuki; Kawakami Rika; Nakagawa Yasuaki; Yasuno Shinji; Usami Satoru; Saitoh Yoshitomo; Li Yuhao; Nakao Kazuwa; Kishimoto Ichirou
    Circulation journal : official journal of the Japanese Circulation Society, 66, 197 - 197, 31 Mar. 2002リポジトリ
  • Increased responsiveness to angiotensin II and cardiac remodeling of mice lacking guanylyl cyclase-A, a natriuretic peptide receptor
    Y Saito; YH Li; Kishimoto, I; M Harada; K Kuwahara; Hamanaka, I; Y Adachi; Y Adachi; Y Adachi; Y Adachi
    CIRCULATION, 104(17), 22 - 22, Oct. 2001, Not invitedWebofScienceリポジトリ
  • Pharmacological and genetic blockades of angiotensin II type 1A receptors markedly improve cardiac fibrosis in guanylyl cyclase A receptor knockout mice
    Kishimoto, I; YH Li; M Harada; K Kuwahara; T Izumi; N Takahashi; R Kawakami; Y Nakagawa; M Nakanishi; Y Adachi; K Tanimoto; K Nakao
    CIRCULATION, 104(17), 281 - 281, Oct. 2001, Not invitedWebofScienceリポジトリ
  • Neuron-restrictive silencer factor, a novel regulator of fetal cardiac genes, plays a critical role in maintaining cardiac structure and function
    K Kuwahara; Y Saito; K Nakao
    CIRCULATION, 104(17), 155 - 155, Oct. 2001, Not invitedWebofScienceリポジトリ
  • Blockade of the natriuretic peptide receptor guanylyl cyclase-A inhibits NF-kappa B activation and alleviates myocardial ischemia/reperfusion injury
    T Izumi; Y Saito; Kishimoto, I; M Harada; K Kuwahara; Hamanaka, I; N Takahashi; R Kawakami; YH Li; G Takemura; H Fujiwara; DL Garbers; S Mochizuki; K Nakao
    JOURNAL OF CLINICAL INVESTIGATION, 108(2), 203 - 213, Jul. 2001, Not invitedWebofScienceリポジトリ電子ジャーナル
  • Blockade of guanylyl cyclase-A, a natriuretic peptide receptor, reduced myocardial infarct size in a mouse model of ischemia-reperfusion injury
    Kishimoto, I; Y Saito; T Izumi; R Kawakami; M Harada; K Kuwahara; Hamanaka, I; N Takahashi; Y Li; DL Garbers; K Nakao
    CIRCULATION, 102(18), 346 - 346, Oct. 2000, Not invitedWebofScienceリポジトリ
  • A novel strategy for the treatment of LPS-induced left ventricular dysfunction in rat: Application of cytokine resistance.
    Hamanaka, I; Y Saito; Kishimoto, I; K Kuwahara; T Izumi; N Takahashi; M Harada; R Kawakami; K Nakao
    CIRCULATION, 102(18), 533 - 533, Oct. 2000, Not invitedWebofScienceリポジトリ
  • Fibronectin signaling increases BNP gene transcription by inhibiting neuron-restrictive silencer element-dependent repression in rat ventricular myocytes.
    E Ogawa; Y Saito; K Kuwahara; M Harada; Y Miyamoto; Hamanaka, I; N Takahashi; T Izumi; R Kawakami; Kishimoto, I; K Nakao
    CIRCULATION, 102(18), 132 - 132, Oct. 2000, Not invitedWebofScienceリポジトリ
  • Increased mortality due to cardiac rupture after myocardial infarction in mice overexpressing brain natriuretic peptide
    R Kawakami; Y Saito; Kishimoto, I; Y Ogawa; N Tamura; H Chusho; K Kuwahara; Hamanaka, I; N Takahashi; T Izumi; Y Li; K Nakao
    CIRCULATION, 102(18), 347 - 347, Oct. 2000, Not invitedWebofScienceリポジトリ
  • 0700 ヒト血中におけるCardiotrophin-1の存在
    齋藤 能彦; 桑原 宏一郎; 石川 匡洋; 岸本 一郎; 原田 昌樹; 浜中 一郎; 中尾 一和; 浅井 茂; 東久保 千絵; 辻 哲男; 水野 雄二; 吉村 道博; 泰江 弘文
    Japanese circulation journal, 64, 361 - 361, 01 Mar. 2000リポジトリ
  • 0518 gp130による心筋細胞生存維持シグナルにおけるPI3K/Akt経路の関与
    桑原 宏一郎; 斎藤 能彦; 岸本 一郎; 宮本 恵宏; 原田 昌樹; 浜中 一郎; 高橋 伸樹; 和泉 武彦; 川上 利香; 中尾 一和
    Japanese circulation journal, 64, 315 - 315, 01 Mar. 2000リポジトリ
  • 0376 BNPの心肥大抑制作用に関する検討 : トランスジェニックマウスを用いて
    高橋 伸基; 斎藤 能彦; 岸本 一郎; 浜中 一郎; 桑原 宏一郎; 小川 佳宏; 田村 尚久; 中所 英樹; 宮本 恵宏; 原田 昌樹; 和泉 武彦; 川上 利香; 桝田 出; 中尾 一和
    Japanese circulation journal, 64, 279 - 279, 01 Mar. 2000リポジトリ
  • 0377 圧負荷型肥大心での蛋白質合成におけるElongation Factorの意義
    和泉 武彦; 斎藤 能彦; 石川 匡洋; 岸本 一郎; 宮本 恵宏; 原田 昌樹; 桑原 宏一郎; 小川 恵美子; 浜中 一郎; 高橋 伸基; 川上 利香; 桝田 出; 中尾 一和; 錦見 俊雄
    Japanese circulation journal, 64(0), 279 - 279, 01 Mar. 2000, Not invitedリポジトリ
  • 慢性心不全の治療上血漿BNP測定が有用であった拡張型心筋症の1例
    犬塚 康孝; 斉藤 能彦; 高橋 伸基; 岸本 一郎; 原田 昌樹; 浜中 一郎; 桑原 宏一郎; 川上 利香; 菅原 照; 中尾 一和
    日本内分泌学会雑誌, 76, 104 - 104, Feb. 2000リポジトリ
  • Involvement of PI3K/Akt/BAD pathway in gp130-mediated pro-survival/anti-apoptosis signaling in ventricular myocytes.
    K Kuwahara; Y Saito; Kishimoto, I; Y Miyamoto; MM Harada; E Ogawa; Hamanaka, I; N Kajiyama; N Takahashi; T Izumi
    CIRCULATION, 100(18), 63 - 63, Nov. 1999, Not invitedWebofScienceリポジトリ
  • New genes responsible far development of pressure-overload or volume-overload hypertrophy
    T Izumi; Kishimoto, I; Y Miyamoto; M Harada; K Kuwahara; E Ogawa; Hamanaka, I; M Ishikawa; N Takahashi; T Nishikimi; Y Saito
    CIRCULATION, 100(18), 126 - 126, Nov. 1999, Not invitedWebofScienceリポジトリ
  • Outside-in signaling of fibronectin actively leads to myocardial cell hypertrophy by integrin-dependent pathways
    E Ogawa; Y Saito; K Kuwahara; M Harada; Kishimoto, I; Y Miyamoto; Hamanaka, I; N Kajiyama; N Takahashi; T Izumi; R Kawakami; K Nakao
    CIRCULATION, 100(18), 198 - 198, Nov. 1999, Not invitedWebofScienceリポジトリ
  • Involvement of Rho/ROCK pathway in ET-1-induced hypertrophic signaling in cultured neonatal rat ventricular myocytes.
    K Kuwahara; Kishimoto, I; Y Miyamoto; M Harada; E Ogawa; Hamanaka, I; N Kajlyama; N Takahashi; T Izumi; R Kawakami; K Nakao
    CIRCULATION, 100(18), 53 - 53, Nov. 1999, Not invitedWebofScienceリポジトリ
  • 内皮型一酸化窒素合成酵素遺伝子5'隣接領域の-786C変異配列に結合する負の転写因子の同定
    宮本 恵宏; 斉藤 能彦; 原田 昌樹; 中山 雅文; 嶋崎 幸生; 梶山 登; 神谷 重樹; 桑原 宏一郎; 小川 恵美子; 浜中 一郎
    日本内分泌学会雑誌, 75(1), 111 - 111, Apr. 1999, Not invited
  • 内皮型一酸化窒素合成酵素遺伝子5'隣接領域の遺伝子多型の機能解析と本態性高血圧発症との関連研究
    梶山 登; 斎藤 能彦; 宮本 恵宏; 岸本 一郎; 吉村 道博; 中山 雅文; 嶋崎 幸生; 神谷 重樹; 原田 昌樹; 桑原 宏一郎
    日本内分泌学会雑誌, 75(1), 152 - 152, Apr. 1999, Not invited
  • P198 肥大因子ET-1、IL-1βによるBNPおよびMn-SODの遺伝子発現調節
    原田 栄作; 吉村 道博; 嶋崎 幸生; 中山 雅文; 水野 雄二; 久木山 清貴; 小川 久雄; 泰江 弘文; 中川 修; 中川 眞代; 原田 昌樹; 桑原 宏一郎; 斎藤 能彦; 中尾 一和
    Japanese circulation journal, 63(1), 498 - 498, 01 Mar. 1999リポジトリ
  • IS003 Differing role of Extracellular signal-regulated kinase in endothelin-1-induced and cardiotrophin-1-induced hypertrophic signals in cultured cardiac myocytes
    Kuwahara Koichiro; Saitoh Yoshihiko; Kishimoto Ichiro; Ogawa Yoshihiro; Tamura Naohisa; Harada Masaki; Ogawa Emiko; Miyamoto Yoshihiro; Hamanaka Ichiro; Kajiyama Noboru; Takahashi Nobuki; Kawakami Rika; Inobe Yoshito; Izumi Takehiko; Masuda Izuru; Nakao Kazuwa
    Japanese circulation journal, 63(1), 93 - 93, 01 Mar. 1999リポジトリ
  • IS007 Interleukin-1b Induces Myocyte Hypertrophy and Production of B-type Natriuretic Peptide
    Harada Eidsku; Yoshimura Michihiro; Shimasaki Yukio; Nakayama Masafumi; Mizuno Yuji; Kugiyama Kiyotaka; Ogawa Hisao; Yasue Hirofumi; Nakagawa Osamu; Nakagawa Masayo; Harada Masaki; Kuwahara Koichiro; Saitoh Yoshihiko; Nakao Kazuwa
    Japanese circulation journal, 63(1), 94 - 94, 01 Mar. 1999リポジトリ
  • 内皮型一酸化窒素合成酵素遺伝子5'隣接領域の-786C変異配列に結合する負の転写調節因子の同定
    宮本 恵宏; 斎藤 能彦; 原田 昌樹; 梶山 登; 神谷 重樹; 桑原 宏一郎; 小川 惠美子; 浜中 一郎; 高橋 伸基; 和泉 武彦
    Japanese Circulation Journal, 63(Suppl.I), 382 - 382, Mar. 1999, Not invited
  • Cloning of new genes responsible for development of concentric or eccentric hypertrophy.
    M Ishikawa; Y Saito; Y Miyamoto; S Kamitani; T Izumi; K Kuwahara; E Ogawa; Hamanaka, I; N Kajiyama; N Takahashi
    CIRCULATION, 98(17), 697 - 697, Oct. 1998, Not invitedWebofScienceリポジトリ
  • Nitric oxide mediated hypotensive effect of Cardiotrophin-1, a cytokine of interleukin-1 family
    Hamanaka, I; Y Saito; M Harada; K Kuwahara; E Ogawa; M Ishikawa; S Kamitani; N Kajiyama; N Takahashi; T Magaribuchi; K Mori
    CIRCULATION, 98(17), 377 - 378, Oct. 1998, Not invitedWebofScienceリポジトリ
  • Effect of a Glu298Asp missense mutation of human endothelial nitric oxide synthase gene on its enzyme activity
    S Kamitani; Y Saito; Y Miyamoto; N Kajiyama; K Kuwahara; E Ogawa; Hamanaka, I; M Ishikawa; Y Shimasaki; M Nakayama; M Yoshimura
    CIRCULATION, 98(17), 537 - 537, Oct. 1998, Not invitedWebofScienceリポジトリ
  • 内皮型一酸化窒素合成酵素遺伝子Glu298Asp変異と本態性高血圧症との連関研究
    宮本 恵宏; 斎藤 能彦; 梶山 登; 上野 利恵; 神谷 重樹; 原田 昌樹; 石川 匡洋; 桑原 宏一郎; 小川 恵美子; 浜中 一郎; 高橋 伸基; 井野邊 義人; 桝田 出; 伊藤 裕; 吉政 孝明; 中尾 一和; 嶋崎 幸生; 中山 雅文; 吉村 道博; 泰江 弘文
    Therapeutic Research, 19(10), 3072 - 3073, Oct. 1998, Not invited
  • 内皮型一酸化窒素合成酵素遺伝子の5'隣接領域の遺伝子多型と本態性高血圧発症の関連研究
    梶山 登; 斎藤 能彦; 宮本 恵宏; 吉村 道博; 中山 雅文; 嶋崎 幸生; 神谷 重樹; 原田 昌樹; 桑原 宏一郎; 小川 惠美子
    日本内分泌学会雑誌, 74(2), 624 - 624, Sep. 1998, Not invited
  • レニン-アンジオテンシン系構成分子は心筋細胞及び非心筋細胞において細胞特異的に発現する
    原田 昌樹; 斎藤 能彦; 桑原 宏一郎; 小川 恵美子; 石川 匡洋; 高橋 伸基; 宮本 恵宏; 神谷 重樹; 嶋崎 幸生; 浜中 一郎
    日本内分泌学会雑誌, 74(2), 610 - 610, Sep. 1998, Not invited
  • 冠攣縮性狭心症に連関する内皮型一酸化窒素合成酵素遺伝子転写領域の-786C変異配列に結合する負の転写調節因子の精製
    宮本 恵宏; 斉藤 能彦; 中山 雅文; 梶山 登; 嶋崎 幸生; 神谷 重樹; 桑原 宏一郎; 小川 恵美子; 浜中 一郎; 高橋 伸基
    日本内分泌学会雑誌, 74(2), 626 - 626, Sep. 1998, Not invited
  • 本態性高血圧症におけるアンジオテンシン変換酵素遺伝子I/D多型とアンジオテンシンII type1受容体遺伝子A1166C多型のポリジーン効果の検討
    梶山 登; 斎藤 能彦; 宮本 恵宏; 原田 昌樹; 桑原 宏一郎; 小川 恵美子; 浜中 一郎; 神谷 重樹; 高橋 伸基; 井野邊 義人
    日本内分泌学会雑誌, 74(2), 611 - 611, Sep. 1998, Not invited
  • In vitro心筋細胞肥大モデルにおいてカルディオトロフィン-1はパラクライン因子として働いている
    桑原 宏一郎; 斎藤 能彦; 宮本 恵宏; 原田 昌樹; 石川 匡洋; 神谷 重樹; 小川 恵美子; 浜中 一郎; 梶山 登; 井野辺 義人
    日本内分泌学会雑誌, 74(2), 625 - 625, Sep. 1998, Not invited
  • フィブロネクチン-インテグリンoutside-in signalingの心筋細胞肥大に対する検討
    小川 惠美子; 斎藤 能彦; 原田 昌樹; 桑原 宏一郎; 宮本 恵宏; 石川 匡洋; 浜中 一郎; 梶山 登; 神谷 重樹; 高橋 伸基
    日本内分泌学会雑誌, 74(2), 630 - 630, Sep. 1998, Not invited
  • Positive association of Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essential hypertension
    Y Miyamoto; Y Saito; N Kajiyama; Y Shimazaki; M Nakayama; S Kamitani; M Harada; M Ishikawa; E Ogawa; K Kuwahara; Hamanaka, I; M Takahashi; Y Inobe; T Yoshimasa; H Itoh; Masuda, I; M Yoshimura; H Yasue; K Nakao
    JOURNAL OF HYPERTENSION, 16, S55 - S55, Jun. 1998, Not invitedWebofScienceリポジトリ
  • Functional analysis of human endothelial nitric oxide synthase (eNOS) with a missense mutation Glu298Asp
    S Kamitani; Y Saito; Y Miyamoto; M Nakayama; Y Shimasaki; N Kajiyama; M Harada; M Ishikawa; K Kuwahara; E Ogawa; Hamanaka, I; N Takahashi; Masuda, I; M Yoshimura; H Yasue; K Nakao
    JOURNAL OF HYPERTENSION, 16, S44 - S44, Jun. 1998, Not invitedWebofScienceリポジトリ
  • IS049 Implication of cardiotrophin-1 in myocyte-nonmyocyte interaction during cardiac hypertrophy in vitro
    Kuwahara Koichiro; Saito Yoshihiko; Masuda Izuru; Miyamoto Yoshihiro; Harada Masaki; Iishikawa Masahiro; Ogawa Emiko; Hamanaka Ichiro; Kajiyama Noboru; Kamitani Shigeki; Simazaki Yukio; Takahashi Nobuki; Inobe Yoshito; Ito Hiroshi; Nakao Kazuwa
    Japanese circulation journal, 62, 29 - 29, 28 Feb. 1998リポジトリ
  • IS040 Positive association between essential hypertension and Glu298Asp polymorphism in the endothelial nitric oxide synthase gene
    Miyamoto Yoshihiro; Saito Yoshihiko; Kajiyama Noboru; Shimasaki Yukio; Nakayama Masahumi; Kamitani Shigeki; Harada Masaki; Ishikawa Masahiro; Ogawa Emiko; Kuwahara Koichiro; Hamanaka Ichiro; Takahashi Nobuki; Inobe Yoshito; Yoshimasa Takaaki; Ito Hiroshi; Masuda Izuru; Yoshimura Michihiro; Yasue Hirifumi; Nakao Kazuwa
    Japanese circulation journal, 62, 25 - 25, 28 Feb. 1998リポジトリ
  • 0308 冠攣縮性狭心症に連関する内皮型一酸化窒素合成酵素遺伝子転写領域の変異部位に結合する陰性転写調節因子の解析
    宮本 恵宏; 斎藤 能彦; 神谷 重樹; 梶山 登; 原田 昌樹; 石川 匡洋; 桑原 宏一郎; 小川 惠美子; 浜中 一郎; 高橋 伸基; 井野邉 義人; 桝田 出; 中尾 一和; 中山 雅文; 嶋崎 幸生; 吉村 道博; 泰江 弘文
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • 0984 フィブロネクチンのインテグリンを介する心筋細胞肥大効果の検討
    小川 惠美子; 斎藤 能彦; 原田 昌樹; 桑原 宏一郎; 宮本 恵宏; 石川 匡洋; 浜中 一郎; 梶山 登; 高橋 伸基; 神谷 重樹; 嶋崎 幸生; 井野邉 義人; 中川 修; 伊藤 裕; 桝田 出; 中尾 一和
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • 0991 心筋細胞および非心筋細胞におけるレニン-アンジオテンシン系構成分子の細胞特異的発現の検討
    原田 昌樹; 斎藤 能彦; 桑原 宏一郎; 小川 惠美子; 石川 匡洋; 高橋 伸基; 宮本 恵宏; 神谷 重樹; 嶋崎 幸生; 浜中 一郎; 梶山 登; 井野邉 義人; 桝田 出; 中川 修; 伊藤 裕; 中尾 一和
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • 1013 本態性高血圧症におけるアンジオテンシン変換酵素遺伝子I/D多型とアンジオテンシンII typel受容体遺伝子A1166C多型の相加作用の検討
    梶山 登; 斎藤 能彦; 宮本 恵宏; 石川 匡洋; 原田 昌樹; 桑原 宏一郎; 小川 恵美子; 浜中 一郎; 井野邉 義人; 嶋崎 幸生; 神谷 重樹; 上野 利恵; 高橋 伸基; 桝田 出; 中尾 一和
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • P148 Cradiotrophin(CT-1)の生体投与における血圧変動の解析
    浜中 一郎; 斎藤 能彦; 宮本 恵宏; 石川 匡洋; 原田 昌樹; 桑原 宏一郎; 小川 惠美子; 梶山 登; 井野邉 義人; 神谷 重樹; 高橋 伸基; 伊藤 裕; 桝田 出; 中尾 一和; 曲渕 達雄; 森 健次郎
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • P550 新しいcDNAスクリーニング法(RLCS法)を用いた遠心性肥大、求心性心肥大に特異的な心肥大因子の検索
    石川 匡洋; 斎藤 能彦; 宮本 恵宏; 原田 昌樹; 桑原 宏一郎; 小川 惠美子; 浜中 一郎; 梶山 登; 神谷 重樹; 高橋 伸基; 井野邉 義人; 嶋崎 幸生; 枡田 出; 中尾 一和
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • P596 心筋細胞肥大刺激によるナトリウム利尿ペプチド遺伝子発現の転写調節機構 : カルディオトロフィン-1とエンドセリン-1との比較
    桑原 宏一郎; 斎藤 能彦; 枡田 出; 宮本 恵宏; 原田 昌樹; 石川 匡洋; 小川 惠美子; 浜中 一郎; 梶山 登; 神谷 重樹; 嶋崎 幸生; 高橋 伸基; 井野邉 義人; 伊藤 裕; 中尾 一和
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • P835 eNOS遺伝子のexon7点変異(Glu298Asp)の機能解析
    神谷 重樹; 斎藤 能彦; 宮本 恵宏; 嶋崎 幸生; 梶山 登; 原田 昌樹; 石川 匡洋; 桑原 宏一郎; 小川 惠美子; 浜中 一郎; 井野邉 義人; 高橋 伸基; 桝田 出; 中尾 一和; 中山 雅文; 吉村 道博; 泰江 弘文
    Japanese circulation journal, 62(0), 28 Feb. 1998, Not invitedリポジトリ
  • Plasma BNP concentration is the most sensitive marker for management of chronic congestive heart failure
    Hamanaka, I; Y Saito; Masuda, I; Y Miyamoto; M Harada; K Kuwahara; E Ogawa; N Kajiyama
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 31(2), 155A - 155A, Feb. 1998, Not invitedWebofScienceリポジトリ
  • Cardiotrophin-1(CT-1), a new agonist for a gp 130 signaling pathway, stimulates brain natriuretic peptide (BNP) secretion more abundantly than endothelin-1(ET-1)
    M Ishikawa; Y Miyamoto; K Kuwahara; E Ogawa; M Harada; Hamanaka, I; N Kajiyama; O Nakagawa; Masuda, I; K Nakao
    CIRCULATION, 96(8), 2025 - 2025, Oct. 1997, Not invitedWebofScienceリポジトリ
  • 0537 Cardiotrophin-1(CT-1)のヒト胎児心及び梗塞心における遺伝子発現
    宮本 恵宏; 斎藤 能彦; 小川 恵美子; 石川 匡洋; 桑原 宏一郎; 原田 昌樹; 中川 修; 桝田 出; 中尾 一和; 伊東 宏晃; 佐川 典正; 森 崇英
    Japanese circulation journal, 61(0), 246 - 246, 05 Mar. 1997, Not invitedリポジトリ
  • 0815 微小心筋梗塞モデルマウス(WBF1)における新しい心筋肥大因子Cardiotrophin-1遺伝子発現 : In situ hybridizationにより検討
    小川 恵美子; 斎藤 能彦; 宮本 恵宏; 石川 匡洋; 桑原 宏一郎; 中川 修; 原田 昌樹; 浜中 一郎; 梶山 登; 伊藤 裕; 桝田 出; 中尾 一和; 勝浦 五郎; 新宅 治幸
    Japanese circulation journal, 61(0), 316 - 316, 05 Mar. 1997, Not invitedリポジトリ
  • 0816 Cardiotrophin-1(CT-1)の心筋細胞肥大作用とANP・BNP分泌刺激作用
    石川 匡洋; 斎藤 能彦; 宮本 恵宏; 桑原 宏一郎; 小川 恵美子; 中川 修; 原田 昌樹; 中山 雅文; 神谷 重樹; 浜中 一郎; 梶山 登; 伊藤 裕; 桝田 出; 中尾 一和
    Japanese circulation journal, 61(0), 05 Mar. 1997, Not invitedリポジトリ
  • 120) ANPの心不全における長期投与効果
    浜中 一郎; 桝田 出; 斎藤 能彦; 中川 修; 宮本 恵宏; 原田 昌樹; 石川 匡洋; 桑原 宏一郎; 小川 恵美子; 梶山 登; 中尾 一和
    Japanese circulation journal, 60(0), 779 - 779, 20 Jan. 1997, Not invitedリポジトリ
  • Augmented expression of cardiotrophin-1 mRNA in the ventricle of genetically hypertensive rats (SHRSP/Izm)
    M. Ishikawa; Y. Saito; Y. Miyamoto; O. Nakagawa; K. Kuwahara; E. Ogawa; M. Harada; I. Masuda; K. Nakao
    Japanese Heart Journal, 38(4), 586, 1997, Not invited
    http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030838987&origin=inwardリポジトリ電子ジャーナル
  • 0063 脳卒中易発症高血圧自然発症ラット(SHRSP/lzm)心室でのCardiotrophin-1(CT-1)遺伝子発現の亢進
    石川 匡洋; 斎藤 能彦; 宮本 恵宏; 桑原 宏一郎; 小川 恵美子; 中川 修; 原田 昌樹; 堀 義和; 谷口 泰代; 伊藤 裕; 桝田 出; 中尾 一和
    Japanese circulation journal, 60(0), 62 - 62, 20 Feb. 1996, Not invitedリポジトリ
  • 0258 血管内皮細胞培養上清中血管平滑筋細胞遊走因子の単離同定 : 内皮由来Heparin-Binding Epidermal Growth Factor(HBEGF)分子型の決定
    斎藤 能彦; 中川 修; 宮本 恵宏; 原田 昌樹; 石川 匡洋; 桑原 宏一郎; 小川 恵美子; 桝田 出; 中尾 一和; 宮本 薫; 赤井 靖宏; 寒川 賢治; 宮田 篤郎; 南野 直人; 松尾 壽之
    Japanese circulation journal, 60(0), 111 - 111, 20 Feb. 1996, Not invitedリポジトリ
  • 0383 心筋肥大因子ヒトカルディオトロフィン1cDNAのクローニング
    宮本 恵宏; 斎藤 能彦; 石川 匡宏; 小川 恵美子; 桑原 宏一郎; 中川 修; 原田 昌樹; 堀 義和; 谷口 泰代; 伊藤 裕; 桝田 出; 中尾 一和
    Japanese circulation journal, 60(0), 142 - 142, 20 Feb. 1996, Not invitedリポジトリ
  • 0384 Cardiotrophin-1の心臓での局在についての検討 : 心筋/非心筋細胞分離培養系を用いて
    桑原 宏一郎; 斎藤 能彦; 宮本 恵宏; 石川 匡洋; 小川 恵美子; 中川 修; 原田 昌樹; 堀 義和; 谷口 泰代; 伊藤 裕; 桝田 出; 中尾 一和
    Japanese circulation journal, 60(0), 143 - 143, 20 Feb. 1996, Not invitedリポジトリ
  • 0933 メチルプレドニゾロン大量療法におけるANPおよびBNPの分泌亢進
    谷口 泰代; 桝田 出; 中川 修; 宮本 恵宏; 原田 昌樹; 桑原 宏一郎; 小川 恵美子; 石川 匡洋; 伊藤 裕; 斉藤 能彦; 中尾 一和
    Japanese circulation journal, 60(0), 281 - 281, 20 Feb. 1996, Not invitedリポジトリ
  • P310 心肥大における心筋細胞・非心筋細胞相互作用の意義 : 非心筋細胞によるANP・BNP分泌調節とその機序の検討
    原田 昌樹; 伊藤 裕; 中川 修; 小川 佳宏; 田村 尚久; 浜 典男; 宮本 恵宏; 石川 匡洋; 堀 義和; 桑原 宏一郎; 小川 恵美子; 谷口 泰代; 吉政 孝明; 桝田 出; 斉藤 能彦; 中尾 一和
    Japanese circulation journal, 60(0), 426 - 426, 20 Feb. 1996, Not invitedリポジトリ
  • Multiple Fistulae of Coronary Arteries to Both Ventricles
    Kohei Shiota; Mika Kinoshita; Naritaka Kimura; Hideo Kurosu; Koichiro Ktjwahara; Chisato Mori
    Japanese Heart Journal, 29(5), 741 - 746, 1988, Not invitedリポジトリ電子ジャーナル

Affiliated academic society

  • 2021 - Present
    日本循環器協会
  • 2018 - Present
    日本腫瘍循環器学会
  • 2018 - Present
    日本心血管インターベンション学会
  • 2017 - Present
    日本心臓リハビリテーション学会(
  • 2016 - Present
    日本肺高血圧・肺循環器学会
  • 2014 - Present
    日本抗加齢医学会
  • 2013 - Present
    日本生理学会
  • 2012 - Present
    国際心臓研究学会(ISHR)日本部会
  • 2011 - Present
    日本高血圧学会
  • 2011 - Present
    日本心エコー図学会
  • 2006 - Present
    日本心臓病学会
  • 2006 - Present
    日本不整脈心電学会
  • 2006 - Present
    日本糖尿病学会
  • 2006 - Present
    日本臨床分子医学会
  • 2000 - Present
    American Heart Association
  • 1998 - Present
    日本心不全学会
  • 1998 - Present
    日本心血管内分泌代謝学会
  • 1995 - Present
    日本内分泌学会
  • 1994 - Present
    日本循環器学会
  • 1992 - Present
    日本内科学会

Research Themes

  • 心不全におけるBNP、ANP前駆体の分泌調節不全の機序解明と新規治療法の開発
    科学研究費助成事業, 日本学術振興会, 基盤研究(C)
    京都大学
    01 Apr. 2022 - 31 Mar. 2025
  • 肺動脈性肺高血圧症におけるTRPC6, CNP経路の研究
    科学研究費助成事業, 日本学術振興会, 基盤研究(C)
    京都大学
    01 Apr. 2022 - 31 Mar. 2025
  • Elucidation of significance of saliva PRPs as a potential biomarker and therapeutic target for aging-associated cardiovascular and renal diseases
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Shinshu University
    01 Apr. 2021 - 31 Mar. 2024
  • 肺動脈性肺高血圧症に対する治療薬としての TRPC3/6阻害薬L862の有効性についての治験準備
    難治性疾患実用化研究事業, 国立研究開発法人日本医療研究開発機構
    2021 - Mar. 2024
  • Elucidation of transcriptional and epigenomic circuit ro reveal molecular mechanisms underlying heart failure and identify novel therapeutic targets
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
    Shinshu University
    01 Apr. 2020 - 31 Mar. 2023
  • Development of novel diagnostic and therapeutic methods for cardiac diseases based on the elucidation of the regulatory mechanism of glycosylation of proBNP
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2019 - 31 Mar. 2022
  • Potential significance of TRPC3/6 and CNP as novel therapeutic targets of pulmonary arterial hypertension
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2018 - 31 Mar. 2021
  • 高齢心不全患者の多剤併用および薬剤性有害事象に関する診療実態調査
    循環器疾患・糖尿病等生活習慣病対策実用化研究事業, 日本医療研究開発機構(AMED)
    2018 - 2020
  • Elucidation of transcriptional and epigenomic regulation for maintaining normal cardiac function
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
    Shinshu University
    01 Apr. 2017 - 31 Mar. 2020
  • Long term follow-up of cardiac function and prognosis after optimal therapy in patients with systemic amyloidosis
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Shinshu University
    01 Apr. 2017 - 31 Mar. 2020
  • Evaluation for regulatory mechanism of glycosylation and secretion of less bioactive proBNP by O-linked glycosylation
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2016 - 31 Mar. 2019
  • Investigation of the significance of MRTF-A, a co-activator of SRF, in the development of obesity that is an underlying risk factor for cardiovascular diseases
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Exploratory Research
    Shinshu University
    01 Apr. 2016 - 31 Mar. 2018
  • Blockade of TRPC6/3 is a Novel Therapeutic Approach Against Pulmonary Arterial Hypertension
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2015 - 31 Mar. 2018
  • Elucidation of the molecular mechanism and clinical application of increased plasma level of BNP precursor in patients with heart failure
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2015 - 31 Mar. 2018
  • Elucidation of epigenetic regulation of gene expresson involved in maintaining cardiac function and metabolism
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
    01 Apr. 2014 - 31 Mar. 2017
  • Impact of exercise therapy on oxidative stress in patients with peripheral artery disease
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B)
    Shinshu University
    01 Apr. 2014 - 31 Mar. 2017
  • Elucidation of significance of vascular CNP-GC-B system in vascular integrity and pathology
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Exploratory Research
    Kyoto University
    01 Apr. 2014 - 31 Mar. 2016
  • Elucidation of pathophysiological significance of glycosylation in the regulatory mechanism of BNP processing
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2013 - 31 Mar. 2016
  • HCN4-luciferase knock-in mouse is a new tool for pacemaker cell reprogramming
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
    Kurume University
    01 Apr. 2012 - 31 Mar. 2016
  • Blockade of TRPC6/3 is a Novel Therapeutic Approach Against Pathological Cardiac Remodeling
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    01 Apr. 2012 - 31 Mar. 2015
  • Significance of reciprocal expression of myocardian and MRTF-A during the development of vascular disease
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Exploratory Research
    Kyoto University
    01 Apr. 2012 - 31 Mar. 2014
  • 新規創薬を目指した生活習慣病・難治性疾患モデル遺伝子変異ラットの開発と解析
    厚生労働科学研究費補助金(厚生科研費), 厚生労働省(MHLW)
    厚生労働省研究事業
    2012 - 2014
  • Elucidation of transcriptional and epigenomic regulation in the development of heart failure
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
    Kyoto University
    01 Apr. 2011 - 31 Mar. 2014
  • Translational research of circulation-regulated peptide using B-type natriuretic peptide and adrenomedullin
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    2011 - 2013
  • 新規カルシウムチャネルTRPC3/6イオンチャネルを標的とした新規心血管病治療薬の開発
    産学が連携した研究開発成果の展開 研究成果展開事業 研究成果最適展開支援プログラム(A-STEP) 探索タイプ
    京都大学
    2011 - 2012
  • Elucidation of significance of TRPM2 in progression of heart failure
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    2010 - 2012
  • Physiological Function of Hormones Derived from Mesenchymal Cells and Its Failure
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (S)
    Kyoto University
    11 May 2009 - 31 Mar. 2014
  • 新規遺伝子変異ラット作製技術に基づく生活習慣病・難治性疾患モデルラットの開発
    厚生労働科学研究費補助金(厚生科研費), 生労働省(MHLW)
    厚生労働省研究事業
    2009 - 2011
  • Elucidation of molecular mechanisms regulating the gene expression of fetal cardiac ion channels and its implication as a novel therapeutic target for the treatment of heart failure
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
    Kyoto University
    2008 - 2010
  • Crosstalk between NRSF-NRSE system and PPAR system contributing to the homeostasis of cardiac myocyte function
    Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
    Kyoto University
    2007 - 2008
  • ヒストンアセチル化酵素の心筋ミトコンドリア形成と細胞生存維持における役割の解明
    科学研究費助成事業, 日本学術振興会, 萌芽研究
    京都大学
    2006 - 2006
  • 心筋細胞の最終分化に関わる転写調節機構の解明
    科学研究費助成事業, 日本学術振興会, 特別研究員奨励費
    京都大学
    2000 - 2002

Academic Contribution Activities

  • Journal of Asian Pacific Society of Cardiology, Editorial Board
    Peer review
    2022 - Present
  • Journal of Cardiology, Associate Editor
    2022 - Present
  • Circulation Journal, Associate Editor
    2021 - Present
  • Journal of Cardiac Failure, Associated Editor
    2021 - Present
  • Peptides, Editorial Advisory Board
    Peer review
    2020 - Present
  • Internal Medicine, Associate Editor
    Peer review
    2019 - 2023
  • Circulation Reports, Associate Editor
    2018 - Present
  • Journal of Cardiology Cases, Associate Editor
    2016 - 2022
  • Circulation Journal, Editorial Board
    Peer review
    2016 - 2021
  • International Heart Journal, Editorial Board
    Peer review
    2015 - Present