原田 真 (ハラダ マコト)
学術研究院（医学系（附属病院））
医学部附属病院 内科（２）
助教
研究者情報
研究キーワード
- メタボロミクス, ANCA関連血管炎, スルファチド, PPARα, 腎臓
ホームページURL
経歴
研究活動情報
受賞
論文
- Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy
Akinori Yamaguchi; Atsuyoshi Mita; Kosuke Sonoda; Makoto Harada; Koji Hashimoto; Hiroshi Imamura; Yuji Kamijo
Therapeutic Apheresis and Dialysis, 2026年06月, 査読有り
- Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals
Aiko Yamada; Makoto Harada; Tadahiko Kikugawa; Takeshi Nakata; Koji Hashimoto; Tsuneo Konta; Yuji Kamijo
Therapeutic Apheresis and Dialysis, 2026年04月, 査読有り
責任著者 - Sequential cryoglobulinemia-associated glomerulonephritis and light-chain amyloidosis in monoclonal gammopathy of renal significance
Yuki Nakayama; Makoto Harada; Koji Hashimoto; Takashi Ehara; Yuji Kamijo
CEN Case Reports, 2026年04月 - The Role of Kidney Biopsy as a Tool for Personalized Treatment Decision-Making in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Nephritis
Makoto Harada; Shotaro Aso; Takayuki Nimura; Kosuke Yamaka; Daiki Aomura; Aiko Yamada; Kosuke Sonoda; Akinori Yamaguchi; Yutaka Kamimura; Tohru Ichikawa; Mamoru Kobayashi; Koji Hashimoto; Yuji Kamijo
Journal of Personalized Medicine, 16(3), 153-153, 2026年03月, 査読有り
筆頭著者, 責任著者 - Proximal Tubule‐Specific Genetic Deficiency of
PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting
Daiki Aomura; Takayuki Nimura; Kosuke Yamaka; Yosuke Yamada; Makoto Harada; Takero Nakajima; Takefumi Kimura; Koji Hashimoto; Hiroyuki Kanno; Motoko Yanagita; Frank J. Gonzalez; Naoki Tanaka; Yuji Kamijo
The FASEB Journal, 2026年01月, 査読有り - Urea cycle modulation by combined SGLT2 inhibitors and metformin
Makoto Harada; Jonathan Adam; Siyu Han; Mengya Shi; Jianhong Ge; Jutta Lintelmann; Alexander Cecil; Sven Zukunft; Cornelia Prehn; Michael Witting; Markus F. Scheerer; Susanne Neschen; Martin Irmler; Johannes Beckers; Jerzy Adamski; Daniel Teupser; Birgit Linkohr; Christian Gieger; Martin Hrabě de Angelis; Annette Peters; Rui Wang-Sattler
BMC Medicine, 2026年01月, 査読有り
筆頭著者 - Effect of Tofogliflozin on Urinary Albumin-to-Creatinine Ratio vs. Metformin in Diabetic Kidney Disease: Rationale and Study Protocol of the TRUTH-DKD Trial
Kazuhiro Kimura; Yoshiko Takagi; Makoto Harada; Shinichiro Ueda; Masatoshi Minamisawa; Kosuke Sonoda; Ako Oiwa; Yoshikazu Yazaki; Shunpei Sakurai; Takeshi Tomita; Kazuaki Kaneko; Kazuya Yamamoto; Noriaki Takama; Shigeki Momose; Yoshito Inobe; Kazutaka Nogi; Megumi Koshikawa; Takuo Misawa; Toshio Kasai; Hiroshi Tsutsui; Noboru Watanabe; Kyohei Yamazaki; Takahide Miyamoto; Takashi Midorikawa; Tatsuya Usui; Tatsuya Saigusa; Hirohiko Motoki; Yoshihiko Saito; Yuji Kamijo; Mitsuhisa Komatsu; Koichiro Kuwahara
Diabetes Therapy, 2026年01月, 査読有り
責任著者 - Integrative Metabolomics of Targeted and Non-Targeted Analyses in T2D Progression
Jianhong Ge; Siyu Han; Mengya Shi; Makoto Harada; Shixiang Yu; Jiaqi Zheng; Cornelia Prehn; Jerzy Adamski; Gabi Kastenmüller; Sabrina Schlesinger; Wolfgang Koenig; Birgit Linkohr; Barbara Thorand; Karsten Suhre; Christian Gieger; Annette Peters; Rui Wang-Sattler
Diabetes Care, 2025年12月, 査読有り - Potential of serum sulfatide levels as a marker for classification and disease activity in lupus nephritis
Kosuke Yamaka; Daiki Aomura; Makoto Harada; Takero Nakajima; Takayuki Nimura; Koji Hashimoto; Naoki Tanaka; Yuji Kamijo
Frontiers in Immunology, 2025年06月, 査読有り
筆頭著者 - LEOPARD: missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer
Siyu Han; Shixiang Yu; Mengya Shi; Makoto Harada; Jianhong Ge; Jiesheng Lin; Cornelia Prehn; Agnese Petrera; Ying Li; Flora Sam; Giuseppe Matullo; Jerzy Adamski; Karsten Suhre; Christian Gieger; Stefanie Hauck; Christian Herder; Michael Roden; Francesco Paolo Casale; Na Cai; Annette Peters; Rui Wang-Sattler
Nature Communications, 2025年04月, 査読有り - Impact of prepared vascular access on mortality and medical expenses in elderly and non-elderly Japanese patients with chronic kidney disease stage G5: a retrospective cohort study
Takayuki Nimura; Makoto Harada; Daiki Aomura; Kosuke Yamaka; Koji Hashimoto; Yuji Kamijo
Clinical and Experimental Nephrology, 2025年03月, 査読有り
筆頭著者 - Dietary Polyunsaturated Fatty Acid Deficiency Impairs Renal Lipid Metabolism and Adaptive Response to Proteinuria in Murine Renal Tubules
Yaping Wang; Pan Diao; Daiki Aomura; Takayuki Nimura; Makoto Harada; Fangping Jia; Takero Nakajima; Naoki Tanaka; Yuji Kamijo
Nutrients, 2025年03月, 査読有り - Role of major cardiovascular surgery-induced metabolic reprogramming in acute kidney injury in critical care.
Velho TR; Pinto F; Ferreira R; Pereira RM; Duarte A; Harada M; Willmann K; Pedroso D; Paixão T; Guerra NC; Neves-Costa A; Santos I; Gouveia E Melo R; Brito D; Almeida AG; Nobre Â; Wang-Sattler R; Köcher T; Pedro LM; Pinto F; Luis Moita
Intensive care medicine, 2025年01月, 査読有り - Novel Membrane Designed Polyether Sulfone Filter Reduces Filtration Membrane Obstruction Rate in Drop-Type With Adjustable Concentrator Cell-Free and Concentrated Ascites Reinfusion Therapy (DC-CART).
Inui K; Yamada Y; Daiki Aomura; Sonoda K; Harada M; Hashimoto K; Yuji Kamijo
Artificial organs, 2024年12月, 査読有り - Lupus Peritonitis Development in a Patient with Coronavirus Disease 2019 on Peritoneal Dialysis: A Case Report.
Yamaka K; Aomura D; Harada M; Nimura T; Hashimoto K; Kamijo Y
The Tohoku journal of experimental medicine, 2024年10月, 査読有り - Anti-C5 monoclonal antibody treatment showing pathological resolution of complement-mediated atypical hemolytic uremic syndrome: a case report.
Kurihara S; Yamaguchi A; Sonoda K; Yamada Y; Harada M; Hashimoto K; Shimojo H; Ikeda Y; Kamijo Y
BMC nephrology, 2024年07月, 査読有り - Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i
Makoto Harada; Jonathan Adam; Marcela Covic; Jianhong Ge; Stefan Brandmaier; Caroline Muschet; Jialing Huang; Siyu Han; Martina Rommel; Markus Rotter; Margit Heier; Robert P. Mohney; Jan Krumsiek; Gabi Kastenmüller; Wolfgang Rathmann; Zhongmei Zou; Sven Zukunft; Markus F. Scheerer; Susanne Neschen; Jerzy Adamski; Christian Gieger; Annette Peters; Donna P. Ankerst; Thomas Meitinger; Tanya L. Alderete; Martin Hrabe de Angelis; Karsten Suhre; Rui Wang-Sattler
Cardiovascular Diabetology, 2024年06月, 査読有り
筆頭著者 - Prediction of Myocardial Infarction Using a Combined Generative Adversarial Network Model and Feature-Enhanced Loss Function
Shixiang Yu; Siyu Han; Mengya Shi; Makoto Harada; Jianhong Ge; Xuening Li; Xiang Cai; Margit Heier; Gabi Karstenmüller; Karsten Suhre; Christian Gieger; Wolfgang Koenig; Wolfgang Rathmann; Annette Peters; Rui Wang-Sattler
Metabolites, 2024年04月, 査読有り - Metabolic effects of SGLT2i and metformin on 3-hydroxybutyric acid and lactate in db/db mice
Makoto Harada; Siyu Han; Mengya Shi; Jianhong Ge; Shixiang Yu; Jonathan Adam; Jerzy Adamski; Markus F. Scheerer; Susanne Neschen; Martin Hrabe de Angelis; Rui Wang-Sattler
International Journal of Biological Macromolecules, 2024年04月, 査読有り
筆頭著者 - Impact of Vascular Access Flow Suppression Surgery on Cervical Artery Circulation: A Retrospective Observational Study
Koji Hashimoto; Makoto Harada; Yosuke Yamada; Taro Kanno; Yutaka Kanno; Yuji Kamijo
Journal of Clinical Medicine, 2024年01月, 査読有り - Investigation of Clinical Features and Association between Vascular Endothelial Injury Markers and Cytomegalovirus Infection Associated with Thrombotic Microangiopathy in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: Case-Based Research
Takayuki Nimura; Daiki Aomura; Makoto Harada; Akinori Yamaguchi; Kosuke Yamaka; Takero Nakajima; Naoki Tanaka; Takashi Ehara; Koji Hashimoto; Yuji Kamijo
International Journal of Molecular Sciences, 2024年01月, 査読有り
責任著者 - Serum sulfatide level is associated with severe systemic vasculitis with kidney involvement.
Aomura D; Harada M; Nakajima T; Nimura T; Yamaka K; Yamada Y; Hashimoto K; Tanaka N; Kamijo Y
Frontiers in immunology, 2023年12月, 査読有り
筆頭著者 - A case of emphysematous pyelonephritis in an older man with poorly controlled type 2 diabetes mellitus.
Nishikawara M; Harada M; Yamazaki D; Kakegawa T; Hashimoto K; Yuji Kamijo
CEN case reports, 2023年09月, 査読有り - A Case of an Elderly Woman Who Developed Corneal Perforation in the Clinical Course of Myeloperoxidase Positive Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Shuhei Kobayashi; Makoto Harada; Aiko Yamada; Yasuhiro Iesato; Koji Hashimoto; Yuji Kamijo
Case Reports in Rheumatology, 2023年08月, 査読有り
責任著者 - Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts.
Shi M; Han S; Klier K; Fobo G; Montrone C; Yu S; Harada M; Henning AK; Friedrich N; Martin Bahls; Dörr M; Nauck M; Völzke H; Homuth G; Grabe HJ; Cornelia Prehn; Adamski J; Suhre K; Rathmann W; Ruepp A; Hertel J; Peters A; Rui Wang-Sattler
Cardiovascular diabetology, 2023年06月, 査読有り - Anti-SARS-CoV-2 IgG antibody titer after BNT162b2 mRNA COVID-19 vaccination in Japanese patients who underwent renal replacement therapy, hemodialysis, peritoneal dialysis, and kidney transplantation.
Iwabuchi R; Harada M; Yamada A; Aomura D; Yamada Y; Sonoda K; Nakazawa H; Sakai K; Mizukami E; Hashimoto K; Yuji Kamijo
Clinical and experimental nephrology, 2023年04月, 査読有り
筆頭著者 - Predictive Factors of Cytomegalovirus Viremia during the Clinical Course of Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis: A Single Center Observational Study
Makoto Harada; Ryohei Iwabuchi; Akinori Yamaguchi; Daiki Aomura; Yosuke Yamada; Kosuke Sonoda; Yutaka Kamimura; Koji Hashimoto; Yuji Kamijo
Journal of Clinical Medicine, 2023年01月, 査読有り
筆頭著者, 責任著者 - Early detection of thiamine deficiency by non-thyroidal illness syndrome in a hemodialysis patient
Daiki Aomura; Yukifumi Kurasawa; Makoto Harada; Koji Hashimoto; Yuji Kamijo
CEN Case Reports, 12(1), 110-115, 2022年08月, 査読有り - Brain MRI detection of early Wernicke's encephalopathy in a hemodialysis patient.
Daiki Aomura; Kurasawa Y; Harada M; Hashimoto K; Kamijo Y
Clinical case reports, 2022年03月, 査読有り - Relationship between glomerular number in fresh kidney biopsy samples and light microscopy samples
Kosuke Sonoda; Makoto Harada; Daiki Aomura; Yuuta Hara; Yosuke Yamada; Akinori Yamaguchi; Koji Hashimoto; Yuji Kamijo
Clinical and Experimental Nephrology, 26(5), 424-434, 2022年02月, 査読有り - Serum Sulfatide Levels as a Biomarker of Active Glomerular Lesion in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single Center Pilot Study
Makoto Harada; Takero Nakajima; Yosuke Yamada; Daiki Aomura; Akinori Yamaguchi; Kosuke Sonoda; Naoki Tanaka; Koji Hashimoto; Yuji Kamijo
Journal of Clinical Medicine, 2022年01月, 査読有り
筆頭著者, 責任著者 - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Developing Pancreatic Lesion and Diabetes Mellitus: A Case Report and Review of the Literature
Aiko Yamada; Makoto Harada; Takahiko Nobuoka; Akinori Yamaguchi; Kosuke Sonoda; Koji Hashimoto; Yuji Kamijo
The Tohoku Journal of Experimental Medicine, 256(2), 161-168, 2022年, 査読有り
責任著者 - Hospital Admission to a Window-Side Bed Does Not Prevent Delirium: A Retrospective Cohort Study of Older Medical Inpatients in General Wards
Daiki Aomura; Yosuke Yamada; Makoto Harada; Koji Hashimoto; Yuji Kamijo
Frontiers in Medicine, 8, 2021年09月, 査読有り - Impact of a change in vascular access flow volume after percutaneous transluminal angioplasty on cardiac function
Koji Hashimoto; Yuji Kamijo; Makoto Harada; Yosuke Yamada; Taro Kanno; Yutaka Kanno
Science Progress, 104(3), 2021年07月, 査読有り - Prevalence of latent tuberculosis infection and its risk factors in Japanese hemodialysis patients
Yohei Ogawa; Makoto Harada; Koji Hashimoto; Yuji Kamijo
Clinical and Experimental Nephrology, 25(11), 1255-1265, 2021年06月, 査読有り - Pemafibrate Protects against Fatty Acid-Induced Nephropathy by Maintaining Renal Fatty Acid Metabolism
Daiki Aomura; Makoto Harada; Yosuke Yamada; Takero Nakajima; Koji Hashimoto; Naoki Tanaka; Yuji Kamijo
Metabolites, 11(6), 372-372, 2021年06月, 査読有り - Comparison of the factors associated with the short-term prognosis between elderly and non-elderly patients with anti-neutrophil cytoplasmic antibody-associated vasculitis: a retrospective observational study
Makoto Harada; Akinori Yamaguchi; Kosuke Sonoda; Yosuke Yamada; Daiki Aomura; Yutaka Kamimura; Koji Hashimoto; Tohru Ichikawa; Mamoru Kobayashi; Yuji Kamijo
Clinical and Experimental Rheumatology, 2021年03月, 査読有り
筆頭著者, 責任著者 - Efficacy of plasma exchange for antineutrophil cytoplasmic antibody-associated systemic vasculitis: a systematic review and meta-analysis
Yosuke Yamada; Makoto Harada; Yuuta Hara; Ryohei Iwabuchi; Koji Hashimoto; Shuhei Yamamoto; Yuji Kamijo
Arthritis Research & Therapy, 23(1), 2021年01月, 査読有り
筆頭著者 - Neurological Symptoms Due to Intracranial Venous Congestion in a Hemodialysis Patient With Arteriovenous Shunted Flow
Takuya Iguchi; Makoto Harada; Shigekazu Kurihara; Tohru Ichikawa; Shunichi Satoh; Mamoru Kobayashi
Kidney International Reports, 5(11), 2097-2101, 2020年11月, 査読有り
責任著者 - Relationship between serum uric acid level and vascular injury markers in hemodialysis patients
Makoto Harada; Kazuaki Fujii; Yosuke Yamada; Wataru Tsukada; Manabu Tsukada; Koji Hashimoto; Yuji Kamijo
International Urology and Nephrology, 52(8), 1581-1591, 2020年06月, 査読有り
筆頭著者 - A Case of Acute Kidney Injury in a Patient with Renal Hypouricemia without Intense Exercise
Daiki Aomura; Kosuke Sonoda; Makoto Harada; Koji Hashimoto; Yuji Kamijo
Case Reports in Nephrology and Dialysis, 10(1), 26-34, 2020年03月, 査読有り - Adequacy of decision-making based on each kidney function estimation method for Japanese living kidney donor candidates: a retrospective observational study
Koji Hashimoto; Makoto Harada; Yosuke Yamada; Mitsutoshi Sugano; Tomonori Minagawa; Teruyuki Ogawa; Osamu Ishizuka; Yuji Kamijo
Renal Replacement Therapy, 6(1), 2020年01月, 査読有り - Cholesterol Emboli Co-Existing with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis in a 76-Year-Old Woman
Risa Kojima; Makoto Harada; Akinori Yamaguchi; Koji Hashimoto; Yuji Kamijo
The Tohoku Journal of Experimental Medicine, 251(1), 61-68, 2020年, 査読有り
責任著者 - Clinical Survey of Decreased Blood Flow Rate in Continuous Renal Replacement Therapy: A Retrospective Observational Study
Makoto Harada; Masafumi Ooki; Kaede Kohashi; Tohru Ichikawa; Mamoru Kobayashi
Critical Care Research and Practice, 2019, 1-8, 2019年11月, 査読有り
筆頭著者, 責任著者 - Relationship Between Immunosuppressive Therapy and the Development of Infectious Complications Among Patients with Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis: A Single-center, Retrospective Observational Study
Makoto Harada; Wataru Ishii; Takeshi Masubuchi; Tohru Ichikawa; Mamoru Kobayashi
Cureus, 2019年09月, 査読有り
筆頭著者, 責任著者 - Nephrotic Syndrome due to Focal Segmental Glomerulosclerosis Complicating Sjögren’s Syndrome: A Case Report and Literature Review
Shigekazu Kurihara; Makoto Harada; Tohru Ichikawa; Takashi Ehara; Mamoru Kobayashi
Case Reports in Rheumatology, 2019, 1-6, 2019年08月, 査読有り
責任著者 - A Case of Heparin-Induced Thrombocytopenia That Developed in the Therapeutic Course of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Taketoshi Nonaka; Makoto Harada; Masahiko Sumi; Wataru Ishii; Tohru Ichikawa; Mamoru Kobayashi
Case Reports in Rheumatology, 2019, 1-4, 2019年07月, 査読有り
責任著者 - Impact of chronic kidney dysfunction on serum Sulfatides and its metabolic pathway in mice
Yosuke Yamada; Makoto Harada; Koji Hashimoto; Ran Guo; Takero Nakajima; Toshihide Kashihara; Mitsuhiko Yamada; Toshifumi Aoyama; Yuji Kamijo
Glycoconjugate Journal, 36(1), 1-11, 2018年12月, 査読有り - Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism
Ran Guo; Xiao Hu; Yosuke Yamada; Makoto Harada; Takero Nakajima; Toshihide Kashihara; Mitsuhiko Yamada; Toshifumi Aoyama; Yuji Kamijo
Hypertension Research, 42(5), 598-609, 2018年12月, 査読有り - A Case of Rapid Progressive Kidney Dysfunction with Severely Calcified Stenotic Aorta
Makoto Harada; Yusuke Miyashita; Tohru Ichikawa; Mamoru Kobayashi
Case Reports in Nephrology and Dialysis, 8(3), 253-260, 2018年11月, 査読有り
筆頭著者, 責任著者 - Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice
Yu Lu; Makoto Harada; Yuji Kamijo; Takero Nakajima; Naoki Tanaka; Eiko Sugiyama; Mamoru Kyogashima; Frank J. Gonzalez; Toshifumi Aoyama
Archives of Toxicology, 93(1), 149-161, 2018年10月, 査読有り
筆頭著者 - Skin-limited arteritis of small muscular arteries with giant cell-rich granulomatous inflammation in a patient with polymyalgia rheumatica
M Kobayashi; H Shimojo; K Shingu; M Harada; H Kanno
Scandinavian Journal of Rheumatology, 47(6), 509-510, 2018年01月, 査読有り - Onset of Takotsubo Syndrome during the Clinical Course of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Case Report
Makoto Harada; Tohru Ichikawa; Mamoru Kobayashi
The Tohoku Journal of Experimental Medicine, 246(4), 251-256, 2018年, 査読有り
筆頭著者, 責任著者 - Modified A-DROP score and mortality in hemodialysis patients with pneumonia
Makoto Harada; Takeshi Masubuchi; Kazuaki Fujii; Yukifumi Kurasawa; Tohru Ichikawa; Mamoru Kobayashi
Renal Replacement Therapy, 3(1), 2017年09月, 査読有り
筆頭著者, 責任著者 - Protein Concentration of Refractory Ascites in Cancer Patients is Reflected by the Presence and Severity of Peritoneal and Liver Metastasis
Yosuke Yamada; Akinori Yamaguchi; Makoto Harada; Yukifumi Kurasawa; Yuuta Hara; Daiki Yamazaki; Satoshi Fujita; Kosuke Sonoda; Tomoe Masuda; Aiko Yamada; Yohei Ogawa; Koji Hashimoto; Yuji Kamijo
Therapeutic Apheresis and Dialysis, 21(3), 263-269, 2017年06月, 査読有り - Technical Performance and Clinical Effectiveness of Drop Type With Adjustable Concentrator‐Cell Free and Concentrated Ascites Reinfusion Therapy
Yosuke Yamada; Makoto Harada; Akinori Yamaguchi; Yasuko Kobayashi; Takashi Chino; Takashi Minowa; Takashi Kosuge; Wataru Tsukada; Koji Hashimoto; Yuji Kamijo
Artificial Organs, 41(12), 1135-1144, 2017年06月, 査読有り - Identification of chronic kidney disease patient characteristics influencing the renoprotective effects of febuxostat therapy: a retrospective follow-up study
Akinori Yamaguchi; Makoto Harada; Yosuke Yamada; Koji Hashimoto; Yuji Kamijo
BMC Nephrology, 18(1), 2017年05月, 査読有り - Coexistence of Anti-Glomerular Basement Membrane Glomerulonephritis and Membranous Nephropathy in a Female Patient with Preserved Renal Function
Aoi Ogawara; Makoto Harada; Tohru Ichikawa; Kazuaki Fujii; Takashi Ehara; Mamoru Kobayashi
The Tohoku Journal of Experimental Medicine, 243(4), 335-341, 2017年, 査読有り
責任著者 - Peroxisome proliferator-activated receptor α-dependent renoprotection of murine kidney by irbesartan
Makoto Harada; Yuji Kamijo; Takero Nakajima; Koji Hashimoto; Yosuke Yamada; Hisashi Shimojo; Frank J. Gonzalez; Toshifumi Aoyama
Clinical Science, 130(21), 1969-1981, 2016年09月, 査読有り
筆頭著者 - Pure red cell aplasia induced by anti-erythropoietin antibodies, well-controlled with tacrolimus
Koji Hashimoto; Makoto Harada; Yuji Kamijo
International Journal of Hematology, 104(4), 502-505, 2016年06月, 査読有り - The Optimal Cut-off Value of Ankle Brachial Index for Screening Cardiovascular Disease Risk in Hemodialysis Patients
M HARADA; W TSUKADA; O TSUKADA; K HASHIMOTO; Y KAMIJO
THE SHINSHU MEDICAL JOURNAL 64 (3), 135-146, 2016, 2016年, 査読有り
筆頭著者 - Acute Phosphate Nephropathy with Diffuse Tubular Injury Despite Limited Calcium Phosphate Deposition
Yosuke Yamada; Makoto Harada; Akinori Yamaguchi; Mai Sugiyama; Taro Kanno; Koji Hashimoto; Takashi Ehara; Hisashi Shimojo; Hidekazu Shigematsu; Yuji Kamijo
Internal Medicine, 55(16), 2229-2235, 2016年, 査読有り - Serum sulfatide abnormality is associated with increased oxidative stress in hemodialysis patients
Huang Yuzhe; Yuji Kamijo; Koji Hashimoto; Makoto Harada; Taro Kanno; Eiko Sugiyama; Mamoru Kyogashima; Tomomasa Oguchi; Takero Nakajima; Yutaka Kanno; Toshifumi Aoyama
Hemodialysis International, 19(3), 429-438, 2015年02月, 査読有り - A case of podocytic infolding glomerulopathy with multiple myeloma
Makoto Harada; Yuji Kamijo; Takashi Ehara; Hisashi Shimojo; Hidekazu Shigematsu; Makoto Higuchi
BMC Nephrology, 15(1), 2014年02月, 査読有り
筆頭著者 - PPARα Activation Protects against Anti-Thy1 Nephritis by Suppressing Glomerular NF-κB Signaling.
Hashimoto K; Kamijo Y; Nakajima T; Harada M; Higuchi M; Ehara T; Shigematsu H; Aoyama T
PPAR research, 2012年05月, 査読有り
MISC
- 慢性腎臓病G4期におけるSGLT2阻害薬新規処方の効果の検証
松井大介; 青村大輝; 山家公輔; 原田真; 橋本幸始; 上條祐司
日本腎臓学会誌(Web), 67(4), 2025年 - ループス腎炎の病型・活動性予測マーカーとしての血清スルファチドの有用性
山家公輔; 青村大輝; 二村駿行; 原田真; 橋本幸始; 上條祐司
日本腎臓学会誌(Web), 67(4), 2025年 - Impact of Prepared Vascular Access on Mortality and Medical Expenses in Elderly and Nonelderly Japanese Patients with CKD Stage G5: A Retrospective Cohort Study
Yuji Kamijo; Takayuki Nimura; Yuki Nakayama; Daiki Aomura; Kosuke Yamaka; Koji Hashimoto; Makoto Harada
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 35(10), 2024年10月
- 全身性血管炎症候群の腎重症度を予測するバイオマーカーとしての血清Sulfatides値の可能性
上條祐司; 青村大輝; 原田真; 二村駿行; 山家公輔; 山田洋輔; 山口晃典; 園田光佑; 橋本幸始
日本腎臓学会誌(Web), 66(4), 2024年 - PPARαの腎保護効果と多臓器連関
上條祐司; 青村大輝; 二村駿行; 山家公輔; 山田洋輔; 原田真; 柳田素子; 橋本幸始
日本生化学会大会(Web), 97th, 2024年 - PPARα in Proximal Tubules Attenuates Ischemic AKI
Takayuki Nimura; Daiki Aomura; Yosuke Yamada; Makoto Harada; Koji Hashimoto; Motoko Yanagita; Yuji Kamijo
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 33(11), 625-626, 2022年11月 - PPARα in Proximal Tubules Maintains Systemic Energy Homeostasis During Starvation
Daiki Aomura; Takayuki Nimura; Yosuke Yamada; Makoto Harada; Koji Hashimoto; Motoko Yanagita; Yuji Kamijo
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 33(11), 197-198, 2022年11月 - Serum Sulfatide Level as a Marker for Differentiation and Activity Assessment in Renal Vasculitis Diseases
Daiki Aomura; Makoto Harada; Takayuki Nimura; Yosuke Yamada; Koji Hashimoto; Yuji Kamijo
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 33(11), 484-484, 2022年11月 - 腎移植患者におけるCovid-19Vaccine接種後の抗体獲得率と関連因子の検討
上條祐司; 岩渕良平; 原田真; 橋本幸始; 皆川倫範; 小川輝之; 石塚修
日本移植学会総会(Web), 58th, 2022年
書籍等出版物
- 腎臓病における血清スルファチド異常の臨床的重要性と出現機序
原田真; 上條祐司, 共著
信州医学雑誌, 2025年10月 - ANCA関連血管炎における血清スルファチド異常の臨床的重要性
信州大学医学部附属病院腎臓内科 原田 真; 上條祐司, Clinical Academic Topics
アレルギーの臨床 2023年10月号 ANCA関連血管炎の病態と治療, 2023年10月 - 免疫チェックポイント阻害薬によるirAEとその管理 8) irAEの治療 腎障害
信州大学医学部附属病院 腎臓内科 原田真, 上條祐司, 免疫チェックポイント阻害薬によるirAEとその管理 8) irAEの治療 腎障害
日本臨牀 79 (増刊号2) 461-464, 2021., 2021年
講演・口頭発表等
- ループス腎炎の病型・活動性予測マーカーとしての血清スルファチドの有用性
山家 公輔; 青村 大輝; 二村 駿行; 原田 真; 橋本 幸始; 上條 祐司
第68回日本腎臓学会学術集会, 2025年06月 - 慢性腎臓病G4期におけるSGLT2阻害薬新規処方の効果の検証
松井 大介; 青村 大輝; 山家 公輔; 原田 真; 橋本 幸始; 上條 祐司
第68回日本腎臓学会学術集会, 2025年06月 - Multi-omics analysis of global longitudinal strain in left and right ventricles
Makoto Harada; Rui Wang-Sattler
EU IMI2 CARDIATEAM project (Paris, France), 2024年09月 - Metabolic effects of metformin and its combination of SGLT 2 inhibitor
Makoto Harada; Rui Wang-Sattler
12th Grainau Workshop of Genetic Epidemiology (Grainau, Germany), 2024年07月 - 全身性血管炎症候群の腎重症度を予測するバイオマーカーとしての血清Sulfatides値の可能性
上條 祐司; 青村 大輝; 原田 真; 二村 駿行; 山家 公輔; 山田 洋輔; 山口 晃典; 園田 光佑; 橋本 幸始
第67回日本腎臓学会学術集会, 2024年06月 - 虚血性急性腎障害の重症化阻止に腎臓のPPARαは重要な役割を果たす
二村 駿行; 青村 大輝; 山家 公輔; 山田 洋輔; 原田 真; 橋本 幸始; 柳田 素子; 上條 祐司
第66回日本腎臓学会学術集会, 2023年06月 - Systemic metabolomic effects of combination therapy of SGLT2i with metformin
Makoto Harada; Rui Wang-Sattler
11th Grainau Workshop of Genetic Epidemiology (Grainau, Germany), 2023年05月 - 現場評価による腎生検検体の糸球体数と光顕標本の糸球体数の関連
園田 光佑; 原田 真; 青村 大輝; 原 悠太; 山田 洋輔; 山口 晃典; 橋本 幸始; 上條 祐司
第65回日本腎臓学会学術集会, 2022年06月 - ANCA関連血管炎患者における血清Sulfatides値の意義の検討
原田 真; 中嶌 岳郎; 山田 洋輔; 山口 晃典; 園田 光佑; 山田 愛子; 岩渕 良平; 橋本 幸始; 上條 祐司
第65回日本腎臓学会学術集会, 2022年06月 - 腎不全患者における腎代替療法とBNT162b2 mRNA Covid-19 Vaccine接種後の抗体獲得率の検討
岩渕 良平; 原田 真; 橋本 幸始; 上條 祐司
第65回日本腎臓学会学術集会, 2022年06月 - 新しいCKD-EPI式に基づく推算GFR値の日本人における正確性の検討
橋本 幸始; 山田 洋輔; 園田 光佑; 山口 晃典; 原田 真; 上條 祐司
第65回日本腎臓学会学術集会, 2022年06月 - Serum sulfatides, the glycosphingolipids as a biomarker of kidney diseases
Makoto Harada
10th Grainau Workshop of Genetic Epidemiology (Grainau, Germany), 2022年05月 - Close relationship between vascular endothelial function and serum uric acid level in hemodialysis patients
Makoto Harada; Wataru Tsukada; Koji Hashimoto; Yuji Kamijo
American Society of Nephrology (annual congress) 2015, at San Diego, 2015年11月 - The Different Cut-Off Value of Ankle Brachial Index of Hemodialysis Patients, which Predict Cardiovascular Diseases, by Presence of Diabetes Mellitus
Makoto Harada; Wataru Tsukada; Koji Hashimoto; Yuji Kamijo
American Society of Nephrology (annual congress) 2014, at Philadelphia, 2014年11月 - A cross-sectional study investigating relationship between cardiovascular events and several atherosclerotic markers in Japanese hemodialysis patients
Makoto Harada; Wataru Tsukada; Koji Hashimoto; Yuji Kamijo
World Congress of Nephrology 2013, at Hongkong, 2013年05月
共同研究・競争的資金等の研究課題
- Systemic metabolomic effects of combination therapy of SGLT2i with metformin
DZD NEXT (Deutsches Zentrum für Diabetesforschung) Conference Travel Grant
2023年 - 腎臓・近位尿細管特異的PPARα (peroxisome-proliferator-activated receptor α)欠損マウスを用いた慢性腎臓病進展過程におけるPPARαの機能解明
バイエル薬品アカデミックサポート2021
2021年 - SGLT2阻害薬による全身性代謝性変化と臓器効果のメカニズムの解明
上原記念生命科学財団海外留学助成リサーチフェローシップ
2021年
