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OGASAWARA Shinji|Shinshu University Researcher List

OGASAWARA Shinji

Academic Assembly School of Science and Technology Institute of Science

Faculty of Science Department of Science Course of Biology 

Assistant Professor 

Researcher Information

Research Keyword

    Influenza virus, optogenetics, RNA editing

Field Of Study

  • Cell biology
  • molecular biology
Research activity information

Paper

  • RNA Overwriting of Cellular mRNA by Cas13b-Directed RNA-Dependent RNA Polymerase of Influenza A Virus
    Shinzi Ogasawara and Sae Ebashi
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(12), 10000-10013, 2023, Refereed, Invited
    Lead, Corresponding電子ジャーナル
  • Replication-competent influenza virus with a protein-responsive multiplication ability
    Shinzi Ogasawara
    New BIOTECHNOLOGY, 77, 100-110, 14 Aug. 2023, Refereed, Not invited
    Lead, Last, Corresponding電子ジャーナル
  • RNA Editing with Viral RNA-Dependent RNA Polymerase
    S. Ogasawara, A Yamada
    ASC synthetic Biology, 1(11), 46-52, Jan. 2022, Refereed
    Lead, Corresponding電子ジャーナル
  • Transcription Driven by Reversible Photocontrol of Hyperstable G-Quadruplexes
    S. Ogasawara
    ACS Synthetic Biology, 7(11), 2507-2513, Nov. 2018
    Lead, CorrespondingWebofScience電子ジャーナル
  • Duration Control of Protein Expression in Vivo by Light-Mediated Reversible Activation of Translation
    S. Ogasawara
    ACS Chemical Biology, 12(2), 351-356, Feb. 2017
    Lead, CorrespondingWebofScience電子ジャーナル
  • Reversible Photoreguration of Gene Expression and Translation
    S. Ogasawara
    Methods Mol. Biol., 1408, 55, 2016
    Lead, Corresponding
  • Control of Cellular Function by Reversible Photoregulation of Translation
    S. Ogasawara
    ChemBioChem, 15(18), 2652-2655, 2014
    Lead, CorrespondingWebofScience電子ジャーナル
  • Template Directed Reversible Photochemical Ligation of Oligodeoxynucleotides
    Nakamura, Shigetaka; Ogasawara, Shinzi; Matuda, Shigeo; Saito, Isao; Fujimoto, Kenzo;
    MOLECULES, 17(1), 163-178, Jan. 2012WebofScience電子ジャーナル
  • Photoresponsive 5 '-cap for the reversible photoregulation of gene expression
    S. Ogasawara, M. Maeda
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21(18), 5457-5459, 2011
    Lead, CorrespondingWebofScience電子ジャーナル
  • Photochromic Nucleobase Photoisomerized by Visible Light
    Ogasawara, Shinzi; Ito, Syoji; Miyasaka, Hiroshi; Maeda, Mizuo;
    Chemistry Letters, 39(9), 956-957, 2010
    Lead, CorrespondingWebofScience電子ジャーナル
  • Reversible Photoswitching of a G-Quadruplex
    S. Ogasawara, M. Maeda
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(36), 6671-6674, 2009
    Lead, CorrespondingWebofScience電子ジャーナル
  • Autonomous DNA computing machine based on photochemical gate transition
    Ogasawara, Shinzi; Ami, Takehiro; Fujimoto, Kenzo;
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(31), 10050-+, 2008
    LeadWebofScience電子ジャーナル
  • Synthesis and reversible photoisomerization of photoswitchable nucleoside, 8-styryl-2 '-deoxyguanosine
    Ogasawara, Shinzi; Saito, Isao; Maeda, Mizuo;
    Tetrahedron Letters, 49(15), 2479-2482, 2008
    Lead, CorrespondingWebofScience電子ジャーナル
  • Straightforward and Reversible Photoregulation of Hybridization by Using a Photochromic Nucleoside
    S. Ogasawara, M. Maeda
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(46), 8839-8842, 2008
    Lead, CorrespondingWebofScience電子ジャーナル
  • C8-alkynyl- and alkylamino substituted 2 '-deoxyguanosines: a universal linker for nucleic acids modification
    Saito, Yoshio; Matsumoto, Katsuhiko; Bag, Subhendu Sekhar; Ogasawara, Shinzi; Fujimoto, Kenzo; Hanawa, Kazuo; Saito, Isao;
    Tetrahedron, 64(16), 3578-3588, 2008WebofScience電子ジャーナル
  • Highly efficient method for constructing a single-stranded comb-like oligonucleotide via reversible photocrosslinking
    Ogasawara, Shinzi; Yoshimura, Yoshinaga; Hayashi, Masayuki; Saito, Isao; Fujimoto, Kenzo;
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 80(11), 2124-2130, 2007
    LeadWebofScience電子ジャーナル
  • Nonenzymatic parallel DNA logic circuits
    Ogasawara, Shinzi; Kyoi, Yoshiaki; Fujimoto, Kenzo;
    ChemBioChem, 8(13), 1520-1525, 2007
    LeadWebofScience電子ジャーナル
  • SNP genotyping by using photochemical ligation
    Ogasawara, Shinzi; Fujimoto, Kenzo;
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 45(27), 4512-4515, 2006
    LeadWebofScience電子ジャーナル
  • Solution of a SAT Problem on a Reversible DNA Photo-crosslinking
    Shinzi Ogasawara, Kenzo Fujimoto
    Chem. Lett., 34, 2005
    Lead
  • Photochemical ODN Manipulation Based on Reversible DNA Photoligation Mediated by Modified Photoresponsive Base
    Masayuki Ogino, Shinzi Ogasawara, Kakehiro Ami, Yoshinaga Yoshimura, Kenzo Fujimoto
    J. Photopolym. Sci. Technol., 18, 507, 2005
  • A Novel Synthesis of Versatile Multiple-Branched DNA (MB-DNA) by Reversible Photochemical Ligation
    S. Ogasawara, K. Fujimoto
    ChemBioChem, 6, 1756, 2005
    Lead

Research Themes

  • Development of smart influenza virus
  • Photo-control of gene expression
  • Development of RNA editing method

Industrial Property Rights

  • 新規プリンヌクレオシド化合物、その異性化方法および光特性を変化させる方法、ならびに光スイッチング型デバイス材料, 5582558, Patent right
    小笠原慎治、前田瑞夫
  • ピリミジンヌクレオシド化合物およびその利用, Patent right
    小笠原慎治、前田瑞夫
  • ヌクレオシド化合物を含んでいるRNA、当該RNAからのタンパク質の生産量を制御する方法、およびヌクレオシド化合物, 5842339, Patent right
    小笠原慎治、前田瑞夫
  • ウイルスのRNA依存性RNAポリメラーゼを用いてRNA配列を編集する方法, Patent right
    小笠原慎治