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伊藤 研一  イトウ ケンイチ

教員組織学術研究院(医学系)電話番号
教育組織医学部 医学科 外科学(乳腺内分泌外科学分野)FAX番号
職名教授メールアドレス
住所〒390-8621 長野県松本市旭3-1-1ホームページURL

更新日:2022/12/14

プロフィール

研究分野
内分泌・甲状腺・副甲状腺・乳腺外科
癌に対する薬物療法
腫瘍学
現在の研究課題
抗腫瘍薬耐性機構の解析

甲状腺未分化癌の発生機構の解析

所属学会
所属学会
日本癌学会
日本内分泌外科学会
日本外科学会
日本乳癌学会
日本臨床腫瘍学会、等

所属学会役職担当
日本外科学会 , 代議員
日本内分泌外科学会 , 理事
日本臨床腫瘍学会 , 協議員
学歴
出身学校・専攻等(大学院を除く)
1988 , 金沢大学 , 医学部

取得学位
医学博士
受賞学術賞
2018 , 日本内分泌外科学会平成29年度「学会賞」
研究職歴等
研究職歴
2019- , 信州大学医学部外科学教室 乳腺内分泌外科学分野 教授
2014- , 信州大学医学部外科学教室(外科学第二) 乳腺内分泌・呼吸器外科部門 教授
2008- , 信州大学医学部外科学教室(外科学第二) 准教授
2003- , 信州大学医学部附属病院遺伝子診療部講師(外科学第二兼任)
2001- , 信州大学医学部(外科学第2講座) 助手
1996-2001 , 信州大学 医学博士
1988-1996 , 信州大学医学部付属病院 研修医

研究活動業績

研究業績(著書・
発表論文等)
論文
著しい副甲状腺機能亢進を呈しながら術前画像診断が困難であった嚢胞性副甲状腺腺腫の1例
信州医学雑誌,70(3):189-194 2022(Jun.)
Author:久保田 諭史, 島田 恭輔, 髙山 昇平, 大場 崇旦, 伊藤 研一, 駒津 光久


The mechanisms involved in the resistance of estrogen receptor-positive breast cancer cells to palbociclib are multiple and change over time
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY,147(11):3211-3224 2021(Nov.)
Author:Ono, Mayu; Oba, Takaaki; Shibata, Tomohiro; Ito, Ken-Ichi;
Keywords:Breast cancer; Cyclin-dependent kinase inhibitor; Drug resistance; Palbociclib; Retinoblastoma gene;


HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
BREAST CANCER RESEARCH AND TREATMENT,186(1):37-51 2021(Feb.)
Author:Oba, Takaaki; Ono, Mayu; Matoba, Hisanori; Uehara, Takeshi; Hasegawa, Yoshie; Ito, Ken-ichi;
Keywords:Eribulin; HDAC inhibitor; HDAC6; Triple-negative breast cancer; Tubulin acetylation;


Prognostic Nutritional Index Is Superior to Neutrophil-to-lymphocyte Ratio as a Prognostic Marker in Metastatic Breast Cancer Patients Treated With Eribulin
ANTICANCER RESEARCH,41(1):445-452 2021(Jan.)
Author:Oba, Takaaki; Maeno, Kazuma; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
Keywords:Prognostic nutritional index; neutrophil-to-lymphocyte ratio; progression-free survival; metastatic breast cancer; eribulin;


Concomitant use of F-18-FDG PET-CT SUVmax is useful in the assessment of Ki67 labeling index in core-needle biopsy specimens of breast cancer
GLAND SURGERY,10(1):1-9 2021(Jan.)
Author:Nakajima, Hiroki; Maeno, Kazuma; Ito, Tokiko; Kanai, Toshiharu; Oba, Takaaki; Ono, Mayu; Takayama, Fumiyoshi; Uehara, Tsuyoshi; Ito, Ken-ichi;
Keywords:Breast cancer; Ki67 labeling index; core needle biopsy; SUVmax;


縦隔リンパ節転移の外科的治療
日本内分泌・甲状腺外科学会雑誌,38(2):63-67 2021
Author:金井 敏晴;網谷 正統;清水 忠史;大野 晃一;小野 真由;大場 崇旦;伊藤 勅子;前野 一真;伊藤 研一
Keywords:甲状腺癌;縦隔郭清;胸骨切開


Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer
PLOS ONE,16(6):e0252822 2021
Author:Watanabe, Takayuki; Oba, Takaaki; Tanimoto, Keiji; Shibata, Tomohiro; Kamijo, Shinobu; Ito, Ken-ichi;


Bone morphogenetic protein-7 expression reflects the high proliferative ability and aggressiveness of thymic epithelial tumors
JOURNAL OF THORACIC DISEASE,12(3):448-456 2020(Mar.)
Author:Miura, Kentaro; Hamanaka, Kazutoshi; Uehara, Tsuyoshi; Momose, Masanobu; Kanai, Yukiko; Matsuoka, Shunichiro; Takeda, Tetsu; Agatsuma, Hiroyuki; Hyogotani, Akira; Ito, Ken-ichi;
Keywords:Bone morphogenetic protein-7 (BMP-7); thymic epithelial tumors; thymoma; thymic cancer;


Comparative efficacy and safety of tyrosine kinase inhibitors for thyroid cancer: a systematic review and meta-analysis
ENDOCRINE JOURNAL,67(12):1215-1226 2020
Author:Oba, Takaaki; Chino, Tatsunori; Soma, Ai; Shimizu, Tadafumi; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi;
Keywords:Thyroid cancer; Tyrosine kinase inhibitor; Adverse event; Meta-analysis;


Neoadjuvant chemotherapy-induced decrease of prognostic nutrition index predicts poor prognosis in patients with breast cancer
BMC CANCER,20(1) 2020
Author:Oba, Takaaki; Maeno, Kazuma; Takekoshi, Daiya; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
Keywords:Prognostic nutritional index; Disease-free survival; Neoadjuvant chemotherapy; Breast cancer;


癌微小環境研究up-date(第5回)癌微小環境に基づいた乳癌治療
Cancer board of the breast = キャンサーボードオブザブレスト,5(2):102-104 2019(Sep.)
Author:伊藤 研一


腹腔鏡下リスク低減卵管卵巣摘出術により両側卵管采に漿液性卵管上皮内病変が発見された遺伝性乳癌卵巣癌症候群の1例
信州医学雑誌,67(3):209-215 2019(Jun.)
Author:鹿島 大靖, 岡 賢二, 品川 真奈花, 山中 桜, 小野 元紀, 竹内 穂高, 井田 耕一, 樋口 正太郎, 山田 靖, 小原 久典, 菊地 範彦, 宮本 強, 橘 涼太, 福嶋 義光, 古庄 知己, 家里 明日美, 伊藤 研一, 浅香 志穂, 上原 剛, 塩沢 丹里


当科における甲状腺低分化癌の臨床的特徴と遠隔成績の検討
日本内分泌・甲状腺外科学会雑誌,36(4):235-239 2019
Author:前野 一真;伊藤 研一;清水 忠史;相馬 藍;竹腰 大也;小野 真由;大場 崇旦;伊藤 勅子;金井 敏晴;上原 剛
Keywords:甲状腺低分化癌;非根治切除;予後不良


甲状腺乳頭癌の再発リスク分類
日本内分泌外科学会雑誌,36(4):209-212 2019
Author:金井敏晴、伊藤研一、千野辰徳、小野真由、大野晃一、伊藤勅子、前野一真


FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells
Oncotarget ,10:1171-1192 2019
Author:Miura K, Oba T, Hamanaka K, Ito K


Lenvatinib(VEGFR阻害)の臨床試験と適正使用 (特集 頭頸部がん・甲状腺がん・希少がん) -- (甲状腺がん)
腫瘍内科 = Clinical oncology,22(4):404-409 2018(Oct.)
Author:伊藤 研一;清水 忠史;相馬 藍;竹腰 大也;小野 真由;大場 崇旦;伊藤 勅子;金井 敏晴;前野 一真
Keywords:lenvatinib;thyroid cancer;radioactive iodine treatment;tyrosine kinase inhibitor


肺癌術後肺炎に対する周術期口腔機能管理の有効性に関する後ろ向き観察研究
信州医学雑誌,66(4):249-256 2018(Aug.)
Author:梶原 稜, 山田 慎一, 西牧 史洋, 近藤 英司, 鎌田 孝広, 小山 力, 松岡 峻一郎, 竹田 哲, 三浦 健太郎, 山田 響子, 濱中 一敏, 伊藤 研一, 栗田 浩


レンバチニブ (特集 期待される新薬 : 分子標的治療薬の効果と副作用) -- (小分子薬)
腫瘍内科 = Clinical oncology,21(6):675-682 2018(Jun.)
Author:伊藤 勅子;伊藤 研一
Keywords:lenvatinib;thyroid cancer;hepatocellular carcinoma;renal cell carcinoma;tyrosine kinase inhibitor


Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition.
Oncotarget,9(33):22986-23002 2018(May)
Author:Oba T, Ito KI.


Increased Expression of Y-Box-Binding Protein-1 in Hind-Limb Muscles During Regeneration from Ischemic Injury in Mice
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE,244(1):53-62 2018(Jan.)
Author:Fuke, Megumi; Narita, Makoto; Wada, Yuko; Seto, Tatsuichiro; Okada, Kenji; Nakayama, Jun; Izumi, Hiroto; Ito, Ken-ichi;
Keywords:critical limb ischemia; ischemic injury; mouse model system; regeneration; YB-1;


初潮とともに急速増大した14歳乳腺線維腺腫の1例
日本臨床外科学会雑誌,79(6):1187-1192 2018
Author:池原 智彦;大場 崇旦;前野 一真;伊藤 研一;小林 翔;上原 剛
Keywords:若年性線維腺腫;エストロゲン;Ki-67


術前化学療法中に扁平上皮癌成分の増大を生じた混合型乳腺扁平上皮癌の1例
日本内分泌・甲状腺外科学会雑誌,35(4):282-287 2018
Author:金井 敏晴;大場 崇旦;伊藤 勅子;前野 一真;伊藤 研一;玉田 恒
Keywords:乳腺扁平上皮癌;術前化学療法


Chylous leakage after axillary lymph node dissection in a patient with breast cancer
BREAST JOURNAL,24(3):438-440 2018
Author:Oba, Takaaki; Ono, Mayu; Iesato, Asumi; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi;
Keywords:axillary lymph node dissection; breast cancer; chylous leakage;


Analysis of surgical treatment of Masaoka stage III-IV thymic epithelial tumors.
Gen Thorac Cardiovasc Surg,:in press 2018
Author:Hamanaka K, Koyama T, Matsuoka S, Takeda T, Miura K, Yamada K, Hyogotani A, Seto T, Okada K, Ito KI.


A Case of Adenomyoepithelioma of the Breast Showing Strong Uptake of (18) F-Fluorodeoxyglucose on a Positron Emission Tomography.
Breast J,23(2):220-224 2017(Mar.)
Author:Oba T, Maeno K, Ono M, Iesato A, Ito T, Kanai T, Mochizuki Y, Ito KI, Yoshizawa A, Takayama F.


PATZ1 knockdown enhances malignant phenotype in thyroid epithelial follicular cells and thyroid cancer cells
ONCOTARGET,8(47):82754-82772 2017
Author:Iesato, Asumi; Nakamura, Teruo; Izumi, Hiroto; Uehara, Takeshi; Ito, Ken-Ichi;
Keywords:thyroid cancer; PATZ1; dedifferentiation; invasion; migration;


Case of painless thyroiditis that developed during adjuvant chemotherapy for breast cancer.
Int Cancer Conf J,6(4):184-187 2017
Author:Iesato A, Oba T, Ono K, Watanabe T, Ito T, Kanai T, Maeno K, Ito K.


Human 3 beta-hydroxysteroid dehydrogenase type 1 in human breast cancer: clinical significance and prognostic associations
CANCER MEDICINE,5(7):1405-1415 2016(Jul.)
Author:Hanamura, Toru; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Shimojo, Yasuyo; Uehara, Takeshi; Suzuki, Takashi; Hayashi, Shin-ichi; Ito, Ken-ichi;
Keywords:3 beta-hydroxysteroid dehydrogenase type 1; breast cancer; clinical significance; prognosis; steroid metabolism;


女性のがん患者の生活・生命の質(QOL)の実態調査 : 術後1年間のQOL調査結果から
信州大学医学部附属病院看護研究集録,45(1):1-6 2016(Mar.)
Author:増樺京子, 竹内沙弥香, 所真由美, 執印抄枝子, 青柳美恵子, 伊藤勅子, 伊藤研一, 樋口正太郎, 塩沢丹里


Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review
ONCOTARGETS AND THERAPY,9:1641-1646 2016
Author:Oba, Takaaki; Ono, Mayu; Iesato, Asumi; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi; Tateishi, Ayako; Yoshizawa, Akihiko; Takayama, Fumiyoshi;
Keywords:breast cancer; estrogen receptor; endocrine therapy;


ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines
ONCOTARGET,7(43):70011-70027 2016
Author:Oba, Takaaki; Izumi, Hiroto; Ito, Ken-ichi;
Keywords:eribulin; drug resistance; breast cancer; ABCB1; ABCC11;


Significance of sentinel lymph nodes with low gamma counts in breast cancer patients via radioisotopic sentinel lymph node biopsy
Arch Surg Oncol,2:1 2016
Author:Maeno K, Ito T, Koyama H, Kanai T, Mochizuki Y, Ito K


Breast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature
ONCOTARGETS AND THERAPY,8:91-97 2015
Author:Iesato, Asumi; Oba, Takaaki; Ono, Mayu; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ishizaka, Katsuhiko; Kitabatake, Hiroyuki; Takeuchi, Daisuke; Suzuki, Akira; Nakayama, Jun; Ito, Ken-ichi;
Keywords:gastric carcinoma; breast metastasis; signet-ring cell carcinoma; gastric cancer; breast cancer;


Coexpression of EpCAM, CD44 Variant Isoforms and Claudin-7 in Anaplastic Thyroid Carcinoma
PLOS ONE,9(4):e94487 2014
Author:Okada, Toshihiro; Nakamura, Teruo; Watanabe, Takayuki; Onoda, Naoyoshi; Ashida, Atsuko; Okuyama, Ryuhei; Ito, Ken-ichi;


Rapid tumor necrosis and massive hemorrhage induced by bevacizumab and paclitaxel combination therapy in a case of advanced breast cancer
ONCOTARGETS AND THERAPY,6:1393-1398 2013
Author:Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Murayama, Koichi; Koyama, Hiroshi; Maeno, Kazuma; Mochizuki, Yasuhiro; Iesato, Asumi; Hanamura, Toru; Okada, Toshihiro; Watanabe, Takayuki; Ito, Ken-ichi;
Keywords:bevacizumab; breast cancer; necrosis; hemorrhage; adverse event; paclitaxel;


Expression of Polypeptide N-Acetylgalactosaminyl Transferase-3 and Its Association with Clinicopathological Factors in Thyroid Carcinomas
THYROID,23(12):1553-1560 2013
Author:Mochizuki, Yasuhiro; Ito, Ken-ichi; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun;


Association of Nuclear YB-1 Localization With Lung Resistance-related Protein and Epidermal Growth Factor Receptor Expression in Lung Cancer
CLINICAL LUNG CANCER,13(5):375-384 2012(Sep.)
Author:Hyogotani, Akira; Ito, Ken-ichi; Yoshida, Kazuo; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun;
Keywords:Epidermal growth factor receptor; Lung cancer; Lung resistance-related protein; prognosis; Y-box binding protein 1;


Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer
BREAST CANCER RESEARCH AND TREATMENT,133(1):145-159 2012(May)
Author:Ito, Tokiko; Kamijo, Shinobu; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun; Ito, Ken-ichi;
Keywords:YB-1; Breast cancer; Endocrine therapy; Crosstalk;


Multimodality therapeutic outcomes In anaplastic thyroid carcinoma: Improved survival in subgroups of patients with localized primary tumors
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK,34(2):230-237 2012(Feb.)
Author:Ito, Ken-ichi; Hanamura, Toru; Murayama, Koichi; Okada, Toshihiro; Watanabe, Takayuki; Harada, Michihiko; Ito, Tokiko; Koyama, Hiroshi; Kanai, Toshiharu; Maeno, Kazuma; Mochizuki, Yasuhiro; Amano, Jun;
Keywords:anaplastic thyroid carcinoma; surgical treatment; chemotherapy; radiation; multimodality approach;


Full-thickness chest-wall resection followed by thorax reconstruction for recurrent malignant phyllodes tumor
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY,16(2):156-160 2011(Apr.)
Author:Ito, Tokiko; Ito, Ken-ichi; Okada, Toshihiro; Murayama, Koichi; Hanamura, Toru; Kanai, Toshiharu; Maeno, Kazuma; Mochizuki, Yasuhiro; Kondo, Ryoichi; Amano, Jun; Osada, Yoshiro; Asano, Koji;
Keywords:Phyllodes tumor; Full-thickness chest-wall resection; Composix mesh; Musculocutaneous flap;


Upregulation of the apoptosis-related inflammasome in cardiac allograft rejection
JOURNAL OF HEART AND LUNG TRANSPLANTATION,29(3):352-359 2010(Mar.)
Author:Seto, Tatsuichiro; Kamijo, Shinobu; Wada, Yuko; Yamaura, Kazuhiro; Takahashi, Kohei; Komatsu, Kazunori; Otsu, Yoshinori; Terasaki, Takamitsu; Fukui, Daisuke; Amano, Jun; Taniguchi, Shun'ichiro; Sagara, Junji; Ito, Ken-ichi;
Keywords:inflammasome; IL-1beta; ASC (Apoptosis-associated speck-like protein containing a caspase recruitment domain); cardiac transplantation;


ENDOSCOPIC-ASSISTED SKIN-SPARING MASTECTOMY COMBINED WITH SENTINEL NODE BIOPSY
ANZ JOURNAL OF SURGERY,78(10):894-898 2008(Oct.)
Author:Ito, Ken-Ichi; Kanai, Toshiharu; Gomi, Kuniyuki; Watanabe, Takayuki; Ito, Tokiko; Komatsu, Akira; Fujita, Tomoyuki; Amano, Jun;
Keywords:breast cancer; endoscopic surgery; sentinel node biopsy; skin-sparing mastectomy;


Hepatocyte growth factor prevents pulmonary ischernia-reperfusion injury in mice
JOURNAL OF HEART AND LUNG TRANSPLANTATION,26(9):935-943 2007(Sep.)
Author:Makiuchi, Akiko; Yamaura, Kazuhiro; Mizuno, Shinya; Matsumoto, Kunio; Nakamura, Toshikazu; Amano, Jun; Ito, Ken-ichi;


Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel
CLINICAL CANCER RESEARCH,11(24):8837-8844 2005
Author:Fujita T, Ito K, Izumi H, Kimura M, Sano M, Nakagomi H, Maeno K, Hama Y, Shingu K, Tsuchiya S, Kohno K, Fujimori M


Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo
CURRENT MEDICAL RESEARCH AND OPINION,21(5):795-803 2005
Author:Ohtsu Y, Johkura K, Ito K, Akashima T, Asanuma K, Ogiwara N, Oka T, Komuro I, Sasaki K, Amano J


Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation - Induction of tolerance and prevention of cardiac allograft vasculopathy
CIRCULATION,110(12):1650-1657 2004
Author:Yamaura, K; Ito, K; Tsukioka, K; Wada, Y; Makiuchi, A; Sakaguchi, M; Akashima, T; Fujimori, M; Sawa, Y; Morishita, R; Matsumoto, K; Nakamura, T; Suzuki, J; Amano, J; Isobe, M


Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer
CANCER LETTERS,198(1):89-97 2003
Author:Maeno K, Ito K, Hama Y, Shingu K, Kimura M, Sano M, Nakagomi H, Tsuchiya S, Fujimori M


Mutation of proline residues in the NH2-terminal region of the multidrug resistance protein, MRP1(ABCC1): effects on protein expression, membrane localization, and transport function.
Biochim Biophys Acta-Biomember1615,:103-114 2003
Author:Ito K, Weigl LE, Deeley RG, Cole SPC.


Mutation of Trp1254 in the multispecific organic anion transporter, MRP2 (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
J. Biol. Chem,276:38108-38114 2001
Author:Ito K, Oleschuk CJ, Westlake C, Vasa MZ, Deeley RG, Cole SPC


Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport
J. Biol. Chem,276:15616-15624 2001
Author:K. Ito/ S. Cole


上皮小体の位置診断における⁹⁹mTc MIBIシンチグラムの有用性 : 局在画像診断法の検討
信州医学雑誌,46(5):331-335 1998(Oct. 10)
Author:中村 俊幸;小林 信や;藤森 実;新宮 聖士;伊藤 研一;浜 善久;天野 純;橋爪 潔志;伊藤 敦子;小松 誠;山岸 喜代文
Abstract:信州医学雑誌 46(5): 331-335(1998)


Clinical significance of the increased multidrug resistance-associated protein (MRP) gene expression in patients with primary breast cancer
Oncol Res,10:99-109 1998
Author:K. Ito/ M. Fujimori/ J. Amano


Expression of tissue-type plasminogen activator and its inhibitor couples with development of capillary network by human microvascular endothelial cells on Matrigel
J. Cell. Physiol,162:213-024 1995
Author:Ito K, Ryuto M, Ushiro S, Ono M, Sugenoya A, Kuraoka A, Shibata Y, Kuwano M


anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvasucular endothelial cells and neovascularization in mice.
Int J Cancer,55(4):660-666 1993
Author:Ito k, Abe T, Tomita M, Morimoto A, Kohno K, Mori T, Ono M, Sugenoya A, Nishihira T, Kuwano M.

研究費
科学研究費補助金(研究代表者)
2020 - 2022 , 遺伝子変異解析と網羅的遺伝子発現解析を用いた甲状腺未分化癌発症の分子機構の解明 , 基盤研究(C)
2017 - 2019 , 網羅的遺伝子発現解析に基づいた甲状腺未分化癌の分子機構の解明と新規治療戦略の開発 , 基盤研究(C)
2013 - 2015 , 甲状腺未分化癌の分子標的開発に向けたEpCAMの機能解析 , 基盤研究(C)
2005 - 2006 , 抗癌剤感受性試験を用いた、臨床乳癌における抗癌剤治療効果予測因子の解析 , 基盤研究(C)