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KONISHI Hiroaki

Academic OrganizationAcademic Assembly School of Science and Technology Institute of AgricultureTEL
Education and Research OrganizationGraduate School of Medicine, Science and TechnologyFAX
PositionProfessorMail Address
Address8304, Minamiminowa-Village, Kamiina-County 399-4598Web site

Research

Books, Articles, etc.
Articles
Effect of the glycine-rich domain in GAREM2 on its unique subcellular localization upon EGF stimulation
CELLULAR & MOLECULAR BIOLOGY LETTERS,26(1) 2021
Author:Nishino, Tasuku; Oshika, Tsuyoshi; Kyan, Moriatsu; Konishi, Hiroaki;
Keywords:Adaptor protein; Protein aggregation; Glycine-rich; EGF receptor; Tyrosine phosphorylation;


Transglutaminase-mediated cross-linking of WDR54 regulates EGF receptor-signaling
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH,1866(2):285-295 2019(Feb.)
Author:Maeda, Akane; Nishino, Tasuku; Matsunaga, Ryota; Yokoyama, Atsushi; Suga, Hiroshi; Yagi, Toshiki; Konishi, Hiroaki;


Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain
MOLECULAR BRAIN,12(1) 2019
Author:Nishino, Tasuku; Tamada, Kota; Maeda, Akane; Abe, Takaya; Kiyonari, Hiroshi; Funahashi, Yasuhiro; Kaibuchi, Kozo; Takumi, Toru; Konishi, Hiroaki;


GAREM1 regulates the PR interval on electrocardiograms
JOURNAL OF HUMAN GENETICS,63(3):297-307 2018(Mar.)
Author:Kim, Hye Ok; Lim, Ji Eun; Kim, Myung Jun; Kang, Ji-One; Kim, Sung-Moon; Nam, Jeong Min; Tak, Jihoon; Konishi, Hiroaki; Nishino, Tasuku; Koh, In Song; Jin, Young-Ho; Baik, Hyung Hwan; Kim, Jin-Bae; Kim, Mi Kyung; Choi, Bo Youl; Lee, Sang-Hak; Jang, Yangsoo; Shin, Jinho; Oh, Bermseok;


Role of N-myristoylation in stability and subcellular localization of the CLPABP protein
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,495(1):1249-1256 2018
Author:Maeda, Akane; Uchida, Moe; Nishikawa, Sumire; Nishino, Tasuku; Konishi, Hiroaki;


Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS,1861(11):1816-1827 2016(Nov.)
Author:Nishino, Tasuku; Matsunaga, Ryota; Jikihara, Hiroshi; Uchida, Moe; Maeda, Akane; Qi, Guangying; Abe, Takaya; Kiyonari, Hiroshi; Tashiro, Satoshi; Inagaki-Ohara, Kyoko; Shimamoto, Fumio; Konishi, Hiroaki;


Versatile function of the circadian protein CIPC as a regulator of Erk activation
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,469(3):377-383 2016
Author:Matsunaga, Ryota; Nishino, Tasuku; Yokoyama, Atsushi; Nakashima, Akio; Kikkawa, Ushio; Konishi, Hiroaki;


Functional relationship between CABIT, SAM and 14-3-3 binding domains of GAREM1 that play a role in its subcellular localization
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,464(2):616-621 2015
Author:Nishino, Tasuku; Matsunaga, Ryota; Konishi, Hiroaki;


The Detergent-Soluble Cytoplasmic Pool of Survivin Suppresses Anoikis and Its Expression Is Associated with Metastatic Disease of Human Colon Cancer
PLOS ONE,8(2) 2013
Author:Hori, Masato; Miki, Tomoharu; Okamoto, Mayumi; Yazama, Futoshi; Konishi, Hiroaki; Kaneko, Hiroshi; Shimamoto, Fumio; Ota, Takahide; Temme, Achim; Tatsuka, Masaaki;


A Ca2+-dependent Mechanism of Neuronal Survival Mediated by the Microtubule-associated Protein p600
JOURNAL OF BIOLOGICAL CHEMISTRY,288(34):24452-24464 2013
Author:Belzil, Camille; Neumayer, Gernot; Vassilev, Alex P.; Yap, Kyoko L.; Konishi, Hiroaki; Rivest, Serge; Sanada, Kamon; Ikura, Mitsuhiko; Nakatani, Yoshihiro; Minh Dang Nguyen;


A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling
JOURNAL OF BIOLOGICAL CHEMISTRY,288(41):29934-29942 2013
Author:Taniguchi, Tomonori; Tanaka, Shigeru; Ishii, Ayumi; Watanabe, Miyuki; Fujitani, Noriko; Sugeo, Ayusa; Gotoh, Shuhei; Ohta, Takeshi; Hiyoshi, Mineyoshi; Matsuzaki, Hideki; Sakai, Norio; Konishi, Hiroaki;


Inhibitory effect of SPE-39 due to tyrosine phosphorylation and ubiquitination on the function of Vps33B in the EGF-stimulated cells
FEBS LETTERS,586(16):2245-2250 2012
Author:Ishii, Ayumi; Kamimori, Kanae; Hiyoshi, Mineyoshi; Kido, Hiroshi; Ohta, Takeshi; Konishi, Hiroaki;


Role of a tyrosine phosphorylation of SMG-9 in binding of SMG-9 to IQGAP and the NMD complex
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,410(1):29-33 2011
Author:Takeda, Saori; Fujimoto, Ai; Yamauchi, Emiko; Hiyoshi, Mineyoshi; Kido, Hiroshi; Watanabe, Takashi; Kaibuchi, Kozo; Ohta, Takeshi; Konishi, Hiroaki;


New Functional Proteins Identified by Proteomic Analysis in the Epidermal Growth Factor Receptor-mediated Signaling Pathway and Application for Practical Use
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN,130(4):471-477 2010(Apr.)
Author:Tashiro, Kyoko; Konishi, Hiroaki; Nabeshi, Hiromi; Yamauchi, Emiko; Taniguchi, Hisaaki;


Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,399(2):232-237 2010
Author:Tsunematsu, Takumi; Yamauchi, Emiko; Shibata, Hideki; Maki, Masatoshi; Ohta, Takeshi; Konishi, Hiroaki;


D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride
TOXICOLOGY,255(1-2):6-14 2009
Author:Hiyoshi, Mineyoshi; Konishi, Hiroaki; Uemura, Hirokazu; Matsuzaki, Hideki; Tsukamoto, Hideo; Sugimoto, Ryusuke; Takeda, Hideo; Dakeshita, Satoru; Kitayama, Atsushi; Takami, Hidenobu; Sawachika, Fusakazu; Kido, Hiroshi; Arisawa, Kokichi;


GAREM, a Novel Adaptor Protein for Growth Factor Receptor-bound Protein 2, Contributes to Cellular Transformation through the Activation of Extracellular Signal-regulated Kinase Signaling
JOURNAL OF BIOLOGICAL CHEMISTRY,284(30):20206-20214 2009
Author:Tashiro, Kyoko; Tsunematsu, Takumi; Okubo, Hiroko; Ohta, Takeshi; Sano, Etsuko; Yamauchi, Emiko; Taniguchi, Hisaaki; Konishi, Hiroaki;


Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH,1783(6):1036-1047 2008(Jun.)
Author:Sano, Etsuko; Shono, Shigeichi; Tashiro, Kyoko; Konishi, Hiroaki; Yamauchi, Emiko; Taniguchi, Hisaaki;


Contribution of peroxisome-specific isoform of lon protease in sorting PTS1 proteins to peroxisomes
JOURNAL OF BIOCHEMISTRY,143(5):649-660 2008(May)
Author:Omi, Sizue; Nakata, Rie; Okamura-Ikeda, Kazuko; Konishi, Hiroaki; Taniguchi, Hisaaki;


Proteomic identification of the new functional proteins in the EGF receptor-mediated signaling pathway
SEIKAGAKU,79(8):781-785 2007(Aug.)
Author:Konishi, Hiroaki;


Muc4 is required for activation of ErbB2 in signet ring carcinoma cell lines
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,355(1):200-203 2007
Author:Yokoyama, Atsushi; Shi, Bin-Hai; Kawai, Takayuki; Konishi, Hiroaki; Andoh, Ryota; Tachikawa, Hiroyuki; Ihara, Sayoko; Fukui, Yasuhisa;


Mutation of the P13 ' kinase gene in a human colon carcinoma cell line, HCC2998
DNA AND CELL BIOLOGY,25(7):399-405 2006(Jul.)
Author:Shi, Bin-Hi; Nashimoto, Takeshi; Andoh, Ryota; Konishi, Hiroaki; Kobayashi, Michimoto; Xu, Qingyun; Ihara, Sayoko; Fukui, Yasuhisa;


Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein
JOURNAL OF BIOLOGICAL CHEMISTRY,281(34):24612-24622 2006
Author:Tashiro, Kyoko; Konishi, Hiroaki; Sano, Etsuko; Nabeshi, Hiromi; Yamauchi, Emiko; Taniguchi, Hisaaki;


CFBP is a novel tyrosine-phosphorylated protein that might function as a regulator of CIN85/CD2AP
JOURNAL OF BIOLOGICAL CHEMISTRY,281(39):28919-28931 2006
Author:Konishi, Hiroaki; Tashiro, Kyoko; Murata, Yasunobu; Nabeshi, Hiromi; Yamauchi, Emiko; Taniguchi, Hisaaki;