Paper

• GAREM1 is involved in controlling body mass in mice and humans
  Tasuku Nishino, Takaya Abe, Mari Kaneko, Masanao Yokohira, Keiko Yamakawa, Katsumi Imaida, Hiroaki Konishi
  Biochemical and biophysical research communications, 628:91-97, 91-97, 2022, Refereed
  Last, Corresponding
• Effect of the glycine-rich domain in GAREM2 on its unique subcellular localization upon EGF stimulation
  Nishino, Tasuku; Oshika, Tsuyoshi; Kyan, Moriatsu; Konishi, Hiroaki;
  CELLULAR & MOLECULAR BIOLOGY LETTERS, 26(1), 2021
• Transglutaminase-mediated cross-linking of WDR54 regulates EGF receptor-signaling
  Maeda, Akane; Nishino, Tasuku; Matsunaga, Ryota; Yokoyama, Atsushi; Suga, Hiroshi; Yagi, Toshiki; Konishi, Hiroaki;
  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1866(2), 285-295, Feb. 2019
• Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain
  Nishino, Tasuku; Tamada, Kota; Maeda, Akane; Abe, Takaya; Kiyonari, Hiroshi; Funahashi, Yasuhiro; Kaibuchi, Kozo; Takumi, Toru; Konishi, Hiroaki;
  MOLECULAR BRAIN, 12(1), 2019
• GAREM1 regulates the PR interval on electrocardiograms
  Kim, Hye Ok; Lim, Ji Eun; Kim, Myung Jun; Kang, Ji-One; Kim, Sung-Moon; Nam, Jeong Min; Tak, Jihoon; Konishi, Hiroaki; Nishino, Tasuku; Koh, In Song; Jin, Young-Ho; Baik, Hyung Hwan; Kim, Jin-Bae; Kim, Mi Kyung; Choi, Bo Youl; Lee, Sang-Hak; Jang, Yangsoo; Shin, Jinho; Oh, Bermseok;
  JOURNAL OF HUMAN GENETICS, 63(3), 297-307, Mar. 2018
• Role of N-myristoylation in stability and subcellular localization of the CLPABP protein
  Maeda, Akane; Uchida, Moe; Nishikawa, Sumire; Nishino, Tasuku; Konishi, Hiroaki;
  Biochemical and biophysical research communications, 495(1), 1249-1256, 2018
• Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse
  Nishino, Tasuku; Matsunaga, Ryota; Jikihara, Hiroshi; Uchida, Moe; Maeda, Akane; Qi, Guangying; Abe, Takaya; Kiyonari, Hiroshi; Tashiro, Satoshi; Inagaki-Ohara, Kyoko; Shimamoto, Fumio; Konishi, Hiroaki;
  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1861(11), 1816-1827, Nov. 2016
• Versatile function of the circadian protein CIPC as a regulator of Erk activation
  Matsunaga, Ryota; Nishino, Tasuku; Yokoyama, Atsushi; Nakashima, Akio; Kikkawa, Ushio; Konishi, Hiroaki;
  Biochemical and biophysical research communications, 469(3), 377-383, 2016
• Functional relationship between CABIT, SAM and 14-3-3 binding domains of GAREM1 that play a role in its subcellular localization
  Nishino, Tasuku; Matsunaga, Ryota; Konishi, Hiroaki;
  Biochemical and biophysical research communications, 464(2), 616-621, 2015
• A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling
  Taniguchi, Tomonori; Tanaka, Shigeru; Ishii, Ayumi; Watanabe, Miyuki; Fujitani, Noriko; Sugeo, Ayusa; Gotoh, Shuhei; Ohta, Takeshi; Hiyoshi, Mineyoshi; Matsuzaki, Hideki; Sakai, Norio; Konishi, Hiroaki;
  JOURNAL OF BIOLOGICAL CHEMISTRY, 288(41), 29934-29942, 2013
• A Ca2+-dependent Mechanism of Neuronal Survival Mediated by the Microtubule-associated Protein p600
  Belzil, Camille; Neumayer, Gernot; Vassilev, Alex P.; Yap, Kyoko L.; Konishi, Hiroaki; Rivest, Serge; Sanada, Kamon; Ikura, Mitsuhiko; Nakatani, Yoshihiro; Minh Dang Nguyen;
  JOURNAL OF BIOLOGICAL CHEMISTRY, 288(34), 24452-24464, 2013
• The Detergent-Soluble Cytoplasmic Pool of Survivin Suppresses Anoikis and Its Expression Is Associated with Metastatic Disease of Human Colon Cancer
  Hori, Masato; Miki, Tomoharu; Okamoto, Mayumi; Yazama, Futoshi; Konishi, Hiroaki; Kaneko, Hiroshi; Shimamoto, Fumio; Ota, Takahide; Temme, Achim; Tatsuka, Masaaki;
  PLOS ONE, 8(2), 2013
• Inhibitory effect of SPE-39 due to tyrosine phosphorylation and ubiquitination on the function of Vps33B in the EGF-stimulated cells
  Ishii, Ayumi; Kamimori, Kanae; Hiyoshi, Mineyoshi; Kido, Hiroshi; Ohta, Takeshi; Konishi, Hiroaki;
  FEBS Letters, 586(16), 2245-2250, 2012
• Role of a tyrosine phosphorylation of SMG-9 in binding of SMG-9 to IQGAP and the NMD complex
  Takeda, Saori; Fujimoto, Ai; Yamauchi, Emiko; Hiyoshi, Mineyoshi; Kido, Hiroshi; Watanabe, Takashi; Kaibuchi, Kozo; Ohta, Takeshi; Konishi, Hiroaki;
  Biochemical and biophysical research communications, 410(1), 29-33, 2011
• New Functional Proteins Identified by Proteomic Analysis in the Epidermal Growth Factor Receptor-mediated Signaling Pathway and Application for Practical Use
  Tashiro, Kyoko; Konishi, Hiroaki; Nabeshi, Hiromi; Yamauchi, Emiko; Taniguchi, Hisaaki;
  YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 130(4), 471-477, Apr. 2010
• Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications
  Tsunematsu, Takumi; Yamauchi, Emiko; Shibata, Hideki; Maki, Masatoshi; Ohta, Takeshi; Konishi, Hiroaki;
  Biochemical and biophysical research communications, 399(2), 232-237, 2010
• GAREM, a Novel Adaptor Protein for Growth Factor Receptor-bound Protein 2, Contributes to Cellular Transformation through the Activation of Extracellular Signal-regulated Kinase Signaling
  Tashiro, Kyoko; Tsunematsu, Takumi; Okubo, Hiroko; Ohta, Takeshi; Sano, Etsuko; Yamauchi, Emiko; Taniguchi, Hisaaki; Konishi, Hiroaki;
  JOURNAL OF BIOLOGICAL CHEMISTRY, 284(30), 20206-20214, 2009
• D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride
  Hiyoshi, Mineyoshi; Konishi, Hiroaki; Uemura, Hirokazu; Matsuzaki, Hideki; Tsukamoto, Hideo; Sugimoto, Ryusuke; Takeda, Hideo; Dakeshita, Satoru; Kitayama, Atsushi; Takami, Hidenobu; Sawachika, Fusakazu; Kido, Hiroshi; Arisawa, Kokichi;
  Toxicology, 255(1-2), 6-14, 2009
• Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule
  Sano, Etsuko; Shono, Shigeichi; Tashiro, Kyoko; Konishi, Hiroaki; Yamauchi, Emiko; Taniguchi, Hisaaki;
  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1783(6), 1036-1047, Jun. 2008
• Contribution of peroxisome-specific isoform of lon protease in sorting PTS1 proteins to peroxisomes
  Omi, Sizue; Nakata, Rie; Okamura-Ikeda, Kazuko; Konishi, Hiroaki; Taniguchi, Hisaaki;
  JOURNAL OF BIOCHEMISTRY, 143(5), 649-660, May 2008
• Proteomic identification of the new functional proteins in the EGF receptor-mediated signaling pathway
  Konishi, Hiroaki;
  SEIKAGAKU, 79(8), 781-785, Aug. 2007
• Muc4 is required for activation of ErbB2 in signet ring carcinoma cell lines
  Yokoyama, Atsushi; Shi, Bin-Hai; Kawai, Takayuki; Konishi, Hiroaki; Andoh, Ryota; Tachikawa, Hiroyuki; Ihara, Sayoko; Fukui, Yasuhisa;
  Biochemical and biophysical research communications, 355(1), 200-203, 2007
• Mutation of the P13 ' kinase gene in a human colon carcinoma cell line, HCC2998
  Shi, Bin-Hi; Nashimoto, Takeshi; Andoh, Ryota; Konishi, Hiroaki; Kobayashi, Michimoto; Xu, Qingyun; Ihara, Sayoko; Fukui, Yasuhisa;
  DNA AND CELL BIOLOGY, 25(7), 399-405, Jul. 2006
• CFBP is a novel tyrosine-phosphorylated protein that might function as a regulator of CIN85/CD2AP
  Konishi, Hiroaki; Tashiro, Kyoko; Murata, Yasunobu; Nabeshi, Hiromi; Yamauchi, Emiko; Taniguchi, Hisaaki;
  JOURNAL OF BIOLOGICAL CHEMISTRY, 281(39), 28919-28931, 2006
• Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein
  Tashiro, Kyoko; Konishi, Hiroaki; Sano, Etsuko; Nabeshi, Hiromi; Yamauchi, Emiko; Taniguchi, Hisaaki;
  JOURNAL OF BIOLOGICAL CHEMISTRY, 281(34), 24612-24622, 2006