論文 (原著)Cdc42 is required for male germline niche development in mice. Cell Rep. ,36(7):109550-109550 2021(Aug. 17) Author:Yoshifumi Mori, Seiji Takashima, Mito Kanatsu-Shinohara, Zheng Yi, Takashi Shinohara
(原著)Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects Scientific Reports,10:10796 2020(Jul. 01) Author:Akihiro Tsuchimoto, Masaaki Tone, Narumi Ogonuki, Masashi Hada, Atsuo Ogura & Seiji Takashima
(原著)FGF2 has distinct molecular functions from GDNF in the mouse germline niche. Stem Cell Reports,10(6):1782-1792 2018(Apr. 19) Author:Masaki K, Sakai M, Kuroki S, Jo J, Hoshina K, Fujimori Y, Oka K, Amano T, Yamanaka T, Tachibana M, Tabata Y, Shiozawa T, Ishizuka O, Hochi S, Takashima S.
(原著)Expression dynamics of self-renewal factors for spermatogonial stem cells in the mouse testis. J. Reprod. Dev.,64(3):267-275 2018(Apr. 16) Author:Sakai M, Masaki K, Aiba S, Tone M, Takashima S.
(総説)Culture and transplantation of spermatogonial stem cells. Stem Cell Reports,29:46-55 2018(Mar. 15) Author:Takashima, S., Shinohara, T.
(総説)Biology and manipulation technologies of male germline stem cells in mammals. Reprod. Med. Biol.,In Press 2018 Author:Takashima, S.
(原著)Direct comparison of Cryotop® vitrification and Bicell® freezing on recovery of functional rat pancreatic islets. Cryobiology,73(3):376-382 2016(Dec. 01) Author:Yamanaka T, Tashima K, Takahashi R, Takashima S, Goto T, Hirabayashi M, Hochi S.
(国内学会発表受賞記念要旨収録)Differential expression of FGF2 and GDNF in the mouse testis J Reprod. Dev. ,62(1):A8 2016(Feb. 20) Author:Yagi, M., Takashima, S.
(原著)Functional differences between GDNF-dependent and FGF2-dependent mouse spermatogonial stem cell self-renewal. Stem Cell Reports,4(3):489-502 2015(Mar. 10) Author:Takashima, S., Kanatsu-Shinohara, M., Tanaka, T., Morimoto, H., Inoue, K., Ogonuki, N., Jijiwa, M., Takahashi, M., Ogura, A., Shinohara, T.
(原著)High revivability of vitrified-warmed bovine mature oocytes after recovery culture with α-tocopherol. Reproduction,149(4):347-355 2015(Jan. 27) Author:Yashiro, I., Tagiri, M., Ogawa, H., Tashima, K., Takashima, S., Hara, H., Hirabayashi, M., Hochi, S.
(原著)Regulation of pluripotency in male germline stem cells by Dmrt1 Genes Dev.,27:1949-1958 2013 Author:Takashima, S., Hirose, M., Ogonuki, N., Ebisuya, M., Inoue, K., Morimoto, H., Kanatsu-Shinohara, M., Nishida, E., Ogura, A., Shinohara, T.
(原著)Reconstitution of mouse spermatogonial stem cell niches in culture Cell Stem Cell,11:567-578 2012 Author:Kanatsu-Shinohara, M., Inoue, K., Takashima, S., Takehashi, M., Ogonuki, N., Morimoto, H., Nagasawa, T., Ogura, A., Shinohara, T.
(原著)Dynamic changes in EpCAM expression during spermatogonial stem cell differentiation in the mouse testis PLos One,6:e23663 2011 Author:Kanatsu-Shinohara, M., Takashima, S., Ishii. K., Shinohara, T.
(原著)Rac mediates mouse spermatogonial stem cell homing to germline niches by regulating transmigration through the blood-testis barrier Cell Stem Cell,9:463-475 2011 Author:Takashima, S., Kanatsu-Shinohara, M., Tanaka, T., Takehashi, M., Morimoto, H., Shinohara, T.
(原著)Genetic influences in mouse spermatogonial stem cell self-renewal J. Reprod. Dev,56:145-153 2010 Author:Kanatsu-Shinohara, M., Ogonuki, N., Miki, H., Inoue, K., Morimoto, H., Takashima, S., Ogura, A., Shinohara, T.
(原著)Transmission distortion by loss of p21 or p27 cyclin-dependent kinase inhibitors following competitive spermatogonial transplantation Proc. Natl. Acad. Sci. USA,107:6210-6215 2010 Author:Kanatsu-Shinohara, M., Takashima, S., Shinohara, T.
(原著)Alpha 1 antitrypsin activity is decreased in human amnion in premature rupture of the fetal membranes Mol. Hum. Reprod.,15:49-57 2009 Author:Izumi-Yoneda, N., Toda, A., Okabe, M., Koike, C., Takashima, S., Yoshida, T., Konishi, I., Saito, S., Nikaido, T.
(原著)Abnormal DNA methyltransferase expression in mouse germline stem cells results in spermatogenic defects Biol. Reprod.,81:155-164 2009 Author:Takashima, S., Takehashi, M., Lee, J., Chuma, S., Okano, M., Hata, K., Suetake, I., Nakatsuji, N., Miyoshi, H., Tajima, S., Tanaka, Y., Toyokuni, S., Sasaki, H., Kanatsu-Shinohara, M., Shinohara, T.
(原著)Genetic reconstruction of mouse spermatogonial stem cell self-renewal in vitro by Ras-cyclin D2 activation Cell Stem Cell,5:76-86 2009 Author:Lee, J., Kanatsu-Shinohara, M., Morimoto, H., Kazuki, Y., Takashima, S., Oshimura, M., Toyokuni, S., Shinohara, T.
(原著)Phenotypic plasticity of mouse spermatogonial stem cells Plos One,4:e7909 2009 Author:Morimoto, H., Kanatsu-Shinohara, M., Takashima, S., Chuma, S., Nakatsuji, N., Takehashi, M., Shinohara, T.
(原著)Characterization of laminin isoforms in human amnion Tissue Cell,40:75-81 2008 Author:Takashima, S., Yasuo, M., Sanzen, N., Sekiguchi, K., Okabe, M., Yoshida, T., Toda, A., Nikaido, T.
(原著)Production of transgenic rats via lentiviral transduction and xenogeneic transplantation of spermatogonial stem cells Biol. Reprod.,79:1121-1128 2008 Author:Kanatsu-Shinohara, M., Kato, M., Takehashi, M., Morimoto, H., Takashima, S., Chuma, S., Nakatsuji, N., Hirabayashi, M., Shinohara, T.
(原著)Homing of mouse spermatogonial stem cells to germline niche depends on beta1-integrin Cell Stem Cell,3:533-542 2008 Author:Kanatsu-Shinohara, M., Takehashi, M., Takashima, S., Lee, J., Morimoto, H., Chuma, S., Raducanu, A., Nakatsuji, N., Fässler, R., Shinohara, T.
(原著)Human amniotic epithelial cells possess hepatocyte-like characteristics and functions Cell Struct. Funct.,29:73-84 2004 Author:Takashima, S., Ise, H., Zhao, P., Akaike, T., Nikaido, T.
(原著)Transplanted human amniotic epithelial cells express connexin 26 and Na-K-ATPase in the inner ear Transplantation,77:1452-1454 2003 Author:Yuge, I., Takumi ,Y., Koyabu, K., Hashimoto, S., Takashima, S., Fukuyama, T., Nikaido, T., Usami, S.
(原著)Analysis of cell viability and differential activity of mouse hepatocytes under 3D and 2D culture in agarose gel Biotechnol. Lett.,21:209-213 1999 Author:Ise, H., Takashima, S., Nagaoka, M., Ferdous, A., Akaike, T.
講演・口頭発表等 (国際学会発表)“Dysregulated interleukin-1 activity results in male infertility” 2017(Oct. 31) Presenter:Kaito Masaki, Shunta Sakanishi, Shigeru Kyuwa, Shigeru Kakuta, and Seiji Takashima
(国際学会発表)“Depletion of recipient germ cells compromises the spermatogenesis of transplanted testis tissue” 2017(Sep. 27) Presenter:Akihiro Tsuchimoto, Masaaki Tone and Seiji Takashima
(国際学会発表)“The role of neuroendocrine system in regulating spermatogenesis” 2017(Sep. 27) Presenter:Shota Aiba, Haruhiko adachi, Kaito Masaki and Seiji Takashima
(国際学会発表)“Ambivalent behavior of fibroblast growth factor 2 in mouse germline niche” 2017(Sep. 27) Presenter:Kaito Masaki, Shunsuke Kuroki, Jun-ichiro Jo, Makoto Tachibana, Yasuhiko Tabata, Seiji Takashima
(国際学会発表/ポスター)“Differential expression of self-renewal factors for spermatogonial stem cells in the mammalian testicular niche” ISSCR annual meating 2017(Jun. 15) Presenter:Seiji Takashima, 、Kaito Masaki、Jun-ichiro Jo, and Yasuhiko Tabata
(国際学会発表)“Dmrt1 suppress the pluripotency of male germline stem cells” 2016(Feb. 18) Presenter:Seiji Takashima, Michiko Hirose, Narumi Ogonuki, Miki Ebisuya, Kimiko Inoue, Hiroko Morimoto, Mito Kanatsu-Shinohara, Atsuo Ogura and Takashi Shinohara
(国際学会発表/ポスター)“Differential expression of spermatogonial self-renewal factors in the mouse testis” International Symposium on Epigenome Dynamics and Regulation in Germ Cell P69 2016(Feb. 17) Presenter:Mizuki Yagi, Haruhiko Adachi, Masaaki Tone, Kaito Masaki, Yamato Kawahara, Hayato Ogawa and Seiji Takashima
(国際学会発表/ポスター)“Glial cell line-derived neurotrophic factor independent self-renewal of murine spermatogonial stem cells” International Symposium on Epigenome Dynamics and Regulation in Germ Cell P60-2 2016(Feb. 17) Presenter:Seiji Takashima, Mito Kanatsu-Shinohara, Takashi Tanaka, Hiroko Morimoto, Kimiko Inoue, Narumi Ogonuki, Mayumi Jijiwa, Masahide Takahashi, Atsuo Ogura and Takashi Shinohara
(国際学会発表/ポスター)“Dmrt1 suppress the pluripotency of male germline stem cells” International Symposium on Epigenome Dynamics and Regulation in Germ Cell P60-1 2016(Feb. 17) Presenter:Seiji Takashima, Michiko Hirose, Narumi Ogonuki, Miki Ebisuya, Kimiko Inoue, Hiroko Morimoto, Mito Kanatsu-Shinohara, Atsuo Ogura and Takashi Shinohara
(プロシーディング)“Alpha 1 antitypsin activity in preterm premature rupture of amniotic membranes” PLACENTA 28 8-9 A37 2007 Presenter:Yoneda, N., Toda, A., Okabe, M., Takashima, S., Yoshida, T., Konishi, I., Saito, S., Nikaido, T.
(国際学会発表)“Human amnion derived cells show characteristics of stem cell and hepatocyte,” The 1st international symposium on developmental biology and tissue engineering 2003 Presenter:Takashima, S., Zhao, P., Akaike, T., and Nikaido, T.
(国際学会発表)“3-D culture of hepatocytes in agarose gel for application to Bio-Artificial Liver system,” 6th world biomaterials congress 2000 Presenter:Takashima, S., Ise, H., and Akaike, T.,
(国際学会発表)“Hepatocytes forming spheroid in agarose gel survive from apoptosis and maintain cell viability and expression of specific function for long-term,” 4th international conference on cellular engineering, 1999 Presenter:Takashima, S., Ise, H., and Akaike, T.
学術論文査読件数 2017-2017 , J. Reprod. Dev 2016-2016 , Scientific reports 2016-2016 , J. Reprod. Dev 2015-2015 , JARG 2015-2015 , J. Reprod. Dev 2015-2015 , J. Reprod. Dev