論文 Effects of fatty acids on inducing endoplasmic reticulum stress in bovine mammary epithelial cells JOURNAL OF DAIRY SCIENCE, in press 2021 Author:Mst Mamuna Sharmin; Moeko Mizusawa; Satoko Hayashi; Wataru Arai; Shotaro Sakata; Shinichi Yonekura*
IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,21(1) 2020 Author:Tokutake, Yukako; Yamada, Keita; Hayashi, Satoko; Arai, Wataru; Watanabe, Takafumi; Yonekura, Shinichi*;
Thermal stimulation at 39 degrees C facilitates the fusion and elongation of C2C12 myoblasts ANIMAL SCIENCE JOURNAL,90(8):1008-1017 2019(Aug.) Author:Hayashi, Satoko; Yonekura, Shinichi*;
Mild heat stress induces transcription of the beta-casein gene via unfolded protein response-activated XBP1 signaling in undifferentiated mammary epithelial cells ANIMAL SCIENCE JOURNAL,90(8):1026-1032 2019(Aug.) Author:Mizusawa, Moeko; Sharmin, Mamuna; Yonekura, Shinichi*;
Adzuki bean (Vigna angularis) extract reduces amyloid- beta aggregation and delays cognitive impairment in Drosophila models of Alzheimer's disease NUTRITION RESEARCH AND PRACTICE,13(1):64-69 2019(Feb.) Author:Miyazaki, Honami; Okamoto, Yoko; Motoi, Aya; Watanabe, Takafumi; Katayama, Shigeru; Kawahara, Sei-ichi; Makabe, Hidefumi; Fujii, Hiroshi; Yonekura, Shinichi*;
Peg1/Mest, an imprinted gene, is involved in mammary gland maturation JOURNAL OF CELLULAR PHYSIOLOGY,234(2):1080-1087 2019(Feb.) Author:Yonekura, Shinichi*; Ohata, Masaki; Tsuchiya, Megumi; Tokita, Hitomi; Mizusawa, Moeko; Tokutake, Yukako;
骨格筋分化の制御に寄与するIRE1-XBP1の機能解明 栄養生理研究会報 = Reviews on Animal Nutrition and Metabolism,63(1):15-22 2019 Author:徳武 優佳子;山田 啓太;林 聡子;坂田 章太郎;米倉 真一
The unfolded protein response is involved in both differentiation and apoptosis of bovine mammary epithelial cells JOURNAL OF DAIRY SCIENCE,101(4):3568-3578 2018(Apr.) Author:Yonekura, Shinichi*; Tsuchiya, Megumi; Tokutake, Yukako; Mizusawa, Moeko; Nakano, Miwa; Miyaji, Makoto; Ishizaki, Hiroshi; Haga, Satoshi;
The role of unfolded protein response in differentiation of mammary epithelial cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,484(4):903-908 2017 Author:Tsuchiya, Megumi; Koizumi, Yumiko; Hayashi, Satoko; Hanaoka, Miyuki; Tokutake, Yukako; Yonekura, Shinichi*
Subcellular Localization and Polymorphism of Bovine FABP4 in Bovine Intramuscular Adipocytes ANIMAL BIOTECHNOLOGY,27(2):96-103 2016 Author:Yonekura, Shinichi*; Hirota, Shohei; Miyazaki, Honami; Tokutake, Yukako;
ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,16(8):18628-18641 2015(Aug.) Author:Tokutake, Yukako; Yamada, Keita; Ohata, Masaki; Obayashi, Yoshihito; Tsuchiya, Megumi; Yonekura, Shinichi*
Soluble extract of soybean fermented with Aspergillus oryzae GB 107 inhibits fat accumulation in cultured 3T3-L1 adipocytes NUTRITION RESEARCH AND PRACTICE,9(4):439-444 2015(Aug.) Author:So, Kyoung-Ha; Suzuki, Yasuki; Yonekura, Shinichi; Suzuki, Yutaka; Lee, Chan Ho; Kim, Sung Woo; Katoh, Kazuo; Roh, Sang-Gun;
Histological analysis of glucagon-like peptide-1 receptor expression in chicken pancreas CELL AND TISSUE RESEARCH,357(1):55-61 2014(Jul.) Author:Watanabe, Takafumi; Nishimura, Kei; Hosaka, Yoshinao Z.; Shimosato, Takeshi; Yonekura, Shinichi; Suzuki, Daisuke; Takemoto, Chihiro; Monir, Mohammad Moniruzzaman; Hiramatsu, Kohzy;
Effect of single nucleotide polymorphisms in GH gene promoter region on carcass traits and intramuscular fatty acid compositions in Japanese Black cattle LIVESTOCK SCIENCE,165:15-21 2014(Jul.) Author:Sugita, Haruna; Ardiyanti, Astrid; Yokota, Shoko; Yonekura, Shinichi; Hirayama, Takuji; Shoji, Noriaki; Yamauchi, Eri; Suzuki, Keiichi; Katoh, Kazuo; Roh, Sang-Gun;
Influences of protein ingestion on glucagon-like peptide (GLP)-1-immunoreactive endocrine cells in the chicken ileum ANIMAL SCIENCE JOURNAL,85(5):581-587 2014(May) Author:Monir, Mohammad M.; Hiramatsu, Kohzy; Matsumoto, Sachiko; Nishimura, Kei; Takemoto, Chihiro; Shioji, Tomomi; Watanabe, Takafumi; Kita, Kazumi; Yonekura, Shinichi; Roh, Sang Gun
Dexamethasone and Acetate Modulate Cytoplasmic Leptin in Bovine Preadipocytes ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES,27(4):567-573 2014(Apr.) Author:Yonekura, Shinichi*; Hirota, Shohei; Tokutake, Yukako; Rose, Michael T.; Katoh, Kazuo; Aso, Hisashi
Expression of the immunoreactive buckwheat major allergenic storage protein in Lactococcus lactis APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,97(8):3603-3611 2013(Apr.) Author:Shigemori, Suguru; Yonekura, Shinichi; Sato, Takashi; Otani, Hajime; Shimosato, Takeshi
Expression of a Biologically Active GFP-alpha(S1)-Casein Fusion Protein in Lactococcus lactis CURRENT MICROBIOLOGY,64(6):569-575 2012(Jun.) Author:Shigemori, Suguru; Yonekura, Shinichi; Sato, Takashi; Nakanishi, Maya; Otani, Hajime; Shimosato, Takeshi
特異的シナプス形成の分子メカニズム 信州大学農学部紀要,48(1):1-7 2012(Mar.) Author:米倉 真一; Abstract:動物が環境刺激に適切に応答するためには，複雑であるが整然とした神経回路網の存在が必要不可欠である。この神経回路網の形成は，発生過程において，正しい相手と結合することにより形成されるが，その仕組みは分かっておらず，神経科学の学問上でも大きな謎となっている。ショウジョウバエの視覚系は，遺伝学的手法が豊富であり，シナプスの結合に特異性のあることもよく知られていることから，神経回路形成の分子機構解明に際し広く活用されている。近年，ショウジョウバエの行動解析を用いた大規模スクリーニングより，神経回路形成に関与する分子が同定されてきている。本総説では，特異的シナプス形成の分子メカニズムに関する最新の知見について述べると共に，特に，著者が明らかにした特異的シナプス形成におけるＮカドヘリンの機能について紹介する。An animal relies on the complex and stereotyped interneuronal connections in its brain to properlys respond to environmental stimuli. Neurons form exquisitely precise patterns of synaptic connections. Hows this is achieved during development remains a central issue in neurobiology. The Drosophila visual systems has been widely used to study the molecular mechanism of neuronal connectivity due to the powerfuls genetic tools that are available in this system. Using visual behavioral screens in Drosophila, recent studiess have identified some of the gene regulatory and cytoskeletal signaling pathways responsible for the layers -specific targeting of Drosophila photoreceptor axons. In this review, I discuss recent progress towardss understanding the molecular mechanisms that control the projection of photoreceptor axons to theirs appropriate target layers in the optic lobe. Especially, I introduce our studies about N-cadherin functionss in the neuronal connectivity. Keywords:シナプス形成; ショウジョウバエ; 視覚中枢; Nカドヘリン; 遺伝学; neuronal connectivity; Drosophila; visual system; N-cadherin; genetics;
AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster JOURNAL OF CELL SCIENCE,125(3):634-648 2012(Feb. 01) Author:Kametaka, Satoshi; Kametaka, Ai; Yonekura, Shinichi; Haruta, Mineyuki; Takenoshita, Seiichi; Goto, Satoshi; Waguri, Satoshi
Conserved Alternative Splicing and Expression Patterns of Arthropod N-Cadherin PLOS GENETICS,5(4) 2009(Apr.) Author:Hsu, Shu-Ning; Yonekura, Shinichi; Ting, Chun-Yuan; Robertson, Hugh M.; Iwai, Youichi; Uemura, Tadashi; Lee, Chi-Hon; Chiba, Akira
Tiling of R7 axons in the Drosophila visual system is mediated both by transduction of an activin signal to the nucleus and by mutual repulsion NEURON,56(5):793-806 2007(Dec. 06) Author:Ting, Chun-Yuan; Herman, Tory; Yonekura, Shinichi; Gao, Shuying; Wang, Jian; Serpe, Mihaela; O'Connor, Michael B.; Zipursky, S. Lawrence; Lee, Chi-Hon
Alternative splicing expands spatiotemporal expression complexity of arthropod N-Cadherin DEVELOPMENTAL BIOLOGY,306(1):376-376 2007(Jun. 01) Author:Hsu, Shu-Ning; Yonekura, Shinichi; Ting, Chun-Yuan; Robertson, Hugh M.; Lee, Chi-Hon; Chiba, Akira
Adhesive but not signaling activity of Drosophila N-cadherin is essential for target selection of photoreceptor afferents DEVELOPMENTAL BIOLOGY,304(2):759-770 2007(Apr. 15) Author:Yonekura, Shinichi; Xu, Lei; Ting, Chun-Yuan; Lee, Chi-Hon
Drosophila N-cadherin functions in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents DEVELOPMENT,132(5):953-963 2005(Mar.) Author:Ting, CY*; Yonekura, S*; Chung, P; Hsu, SN; Robertson, HM; Chiba, A; Lee, CH. *contributed equally to this work.
Octanoate stimulates cytosolic triacylglycerol accumulation and CD36 mRNA expression but inhibits Acetyl coenzyme A carboxylase activity in primary cultured bovine mammary epithelial cells JOURNAL OF DAIRY RESEARCH,71(4):398-404 2004(Nov.) Author:Yonezawa, T; Yonekura, S; Sanosaka, M; Hagino, A; Katoh, K; Obara, Y
Effects of long-chain fatty acids on cytosolic triacylglycerol accumulation and lipid droplet formation in primary cultured bovine mammary epithelial cells JOURNAL OF DAIRY SCIENCE,87(8):2527-2534 2004(Aug.) Author:Yonezawa, T; Yonekura, S; Kobayashi, Y; Hagino, A; Katoh, K; Obara, Y
Suppressing effects of bisphenol A on the secretory function of ovine anterior pituitary cells CELL BIOLOGY INTERNATIONAL,28(6):463-469 2004 Author:Katoh, K; Matsuda, A; Ishigami, A; Yonekura, S; Ishiwata, H; Chen, C; Obara, Y
Effects of acetate and butyrate on the expression of leptin and short-form leptin receptor in bovine and rat anterior pituitary cells GENERAL AND COMPARATIVE ENDOCRINOLOGY,133(2):165-172 2003(Sep.) Author:Yonekura, S; Senoo, T; Kobayashi, Y; Yonezawa, T; Katoh, K; Obara, Y
In vitro differentiation of a cloned bovine mammary epithelial cell JOURNAL OF DAIRY RESEARCH,69(3):345-355 2002(Aug.) Author:Rose, MT; Aso, H; Yonekura, S; Komatsu, T; Hagino, A; Ozutsumi, K; Obara, Y
Effects of nutritional conditions around weaning on carbonic anhydrase activity in the parotid gland and ruminal and abomasal epithelia of Holstein calves JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY,172(5):379-385 2002(Jul.) Author:Kitade, K; Takahashi, K; Yonekura, S; Katsumata, N; Furukawa, G; Ohsuga, S; Nishita, T; Katoh, K; Obara, Y
Effects of aging and weaning on mRNA expression of leptinand CCK receptors in the calf rumen and abomasum DOMESTIC ANIMAL ENDOCRINOLOGY,22(1):25-35 2002(Mar.) Author:Yonekura, S; Kitade, K; Furukawa, G; Takahashi, K; Katsumata, N; Katoh, K; Obara, Y
Relationship between serum leptin concentrations and the marbling scores in Japanese Black Cattle. Anim Sci J,22:25-35 2002 Author:Yonekura S, Kitade K, Furukawa G, Takahashi K, Katsumata N, Katoh K, Obara Y.
Effects of adenosine 5'-triphosphate and growth hormone on cellular H+ transport and calcium ion concentrations in cloned bovine mammary epithelial cells JOURNAL OF ENDOCRINOLOGY,169(2):381-388 2001(May) Author:Katoh, K; Komatsu, T; Yonekura, S; Ishiwata, H; Hagino, A; Obara, Y
Screening System for Alzheimer's Prevention Factors from the Extract of Dietary Foods. The 2nd International Conference on Agriculture and Agro-Industry 2014(Nov. 21) Author:Yonekura S, Miyazaki H
Abnormal mitochondria cause age-dependent axonal degeneration in Drosophila. The38th annual meeting of the Society for Neuroscience 2008 Author:Yonekura S, Gao S, Nagasao J and Watabe K.
A Genome wide screening for novel cell death related gene. Cold Spring Harbor Laboratory meeting 2007 Author:Yonekura S, Gao S, Takazawa T and Watabe K.
N-cadherin regulatesR7 target selection in Drosophila Visual system. Drosophila Research Conference 2004 Author:Yonekura S, Ting CY, Hung K, Hsu SN, Chiba A and Lee CH.
N-cadherin regulates R7 targetselection in Drosophila Visual system. Cold Spring Harbor Laboratory meeting 2003 Author:Yonekura S, Ting CY, Hung K, Hsu SN, Chiba A and Lee CH.
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