YONEKURA Shinichi

Academic Assembly School of Science and Technology Institute of Agriculture

Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences 

Professor 

Degree

  • Ph.D., Tohoku University

Research Keyword

    Neuroscience, Cell Physiology

Field Of Study

  • Animal Physiology

Mail Address

    yonekura★shinshu-u.ac.jp

Educational Background

  • 1999, Tohoku University, Graduate School of Agricultural Science
  • 2002, Tohoku University, Graduate School of Agricultural Science
  • 1997, Tohoku University, Faculty of Agriculture

Member History

  • 評議員, 北信越畜産学会

Award

  • 2023
    日本畜産学会賞
  • 2023
    Animal Science Journal Reviewers Award
  • 2006
    Fellows Award for Research Excellence in NIH
  • 2004
    Award for Young Scientist from Japanese Society of Animal Science

Paper

  • Effects of starvation-induced negative energy balance on endoplasmic reticulum stress in the liver of cows
    Islam, Md Aminul; Adachi, Shuya; Shiiba, Yuichiroh; Takeda, Ken-ichi; Haga, Satoshi; Yonekura, Shinichi*;
    ANIMAL BIOSCIENCE, 35(1), 22-28, Jan. 2022WebofScience電子ジャーナル
  • XBP1u Is Involved in C2C12 Myoblast Differentiation via Accelerated Proteasomal Degradation of Id3
    Hayashi, Satoko; Sakata, Shotaro; Kawamura, Shotaro; Tokutake, Yukako; Yonekura, Shinichi*;
    Frontiers in Physiology, 13, 796190, 2022WebofScience電子ジャーナル
  • Mild heat stimulation facilitates muscle hypertrophy in C2C12 and mouse satellite cells through myokine release to the culture medium
    Hayashi, Satoko; Yonekura, Shinichi*;
    Biochemical and biophysical research communications, 635, 161-168, 2022WebofScience電子ジャーナル
  • Insulin-like growth factor-1 induces IRE1-XBP1-dependent endoplasmic reticulum biogenesis in bovine mammary epithelial cells
    Sharmin, Mst Mamuna; Hayashi, Satoko; Miyaji, Makoto; Ishizaki, Hiroshi; Matsuyama, Hiroki; Haga, Satoshi; Yonekura, Shinichi*;
    JOURNAL OF DAIRY SCIENCE, 104(11), 12094-12104, Nov. 2021WebofScience電子ジャーナル
  • Protective effects of 5-aminolevulinic acid on heat stress in bovine mammary epithelial cells
    Islam, Md Aminul; Noguchi, Yoko; Taniguchi, Shin; Yonekura, Shinichi*;
    ANIMAL BIOSCIENCE, 34(6), 1006-1013, Jun. 2021WebofScience電子ジャーナル
  • Myogenetic oligodeoxynucleotide (myoDN) recovers the differentiation of skeletal muscle myoblasts deteriorated by diabetes mellitus.
    Nakamura, Shunichi; Yonekura, Shinichi; Shimosato, Takeshi; Takaya, Tomohide
    Frontiers in Physiology, 12, 679152, 24 May 2021リポジトリ
  • 5-ALA Attenuates the Palmitic Acid-Induced ER Stress and Apoptosis in Bovine Mammary Epithelial Cells
    Sharmin, Mst Mamuna; Islam, Md Aminul; Yamamoto, Itsuki; Taniguchi, Shin; Yonekura, Shinichi*;
    MOLECULES, 26(4), Feb. 2021WebofScience電子ジャーナル
  • Effects of fatty acids on inducing endoplasmic reticulum stress in bovine mammary epithelial cells
    Sharmin, Mst Mamuna; Mizusawa, Moeko; Hayashi, Satoko; Arai, Wataru; Sakata, Shotaro; Yonekura, Shinichi*;
    JOURNAL OF DAIRY SCIENCE, 103(9), 8643-8654, Sep. 2020WebofScience電子ジャーナル
  • TRPV4 Increases the Expression of Tight Junction Protein-Encoding Genes via XBP1 in Mammary Epithelial Cells
    Islam, Md Aminul; Mizusawa, Moeko; Sharmin, Mst Mamuna; Hayashi, Satoko; Yonekura, Shinichi*;
    ANIMALS, 10(7), Jul. 2020WebofScience電子ジャーナル
  • IRE1-XBP1 Pathway of the Unfolded Protein Response Is Required during Early Differentiation of C2C12 Myoblasts
    Tokutake, Yukako; Yamada, Keita; Hayashi, Satoko; Arai, Wataru; Watanabe, Takafumi; Yonekura, Shinichi*;
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(1), 2020WebofScience電子ジャーナル
  • Mild heat stress induces transcription of the beta-casein gene via unfolded protein response-activated XBP1 signaling in undifferentiated mammary epithelial cells
    Mizusawa, Moeko; Sharmin, Mamuna; Yonekura, Shinichi*;
    ANIMAL SCIENCE JOURNAL, 90(8), 1026-1032, Aug. 2019WebofScience電子ジャーナル
  • Thermal stimulation at 39 degrees C facilitates the fusion and elongation of C2C12 myoblasts
    Hayashi, Satoko; Yonekura, Shinichi*;
    ANIMAL SCIENCE JOURNAL, 90(8), 1008-1017, Aug. 2019WebofScience電子ジャーナル
  • Peg1/Mest, an imprinted gene, is involved in mammary gland maturation
    Yonekura, Shinichi*; Ohata, Masaki; Tsuchiya, Megumi; Tokita, Hitomi; Mizusawa, Moeko; Tokutake, Yukako;
    JOURNAL OF CELLULAR PHYSIOLOGY, 234(2), 1080-1087, Feb. 2019WebofScience電子ジャーナル
  • Adzuki bean (Vigna angularis) extract reduces amyloid- beta aggregation and delays cognitive impairment in Drosophila models of Alzheimer's disease
    Miyazaki, Honami; Okamoto, Yoko; Motoi, Aya; Watanabe, Takafumi; Katayama, Shigeru; Kawahara, Sei-ichi; Makabe, Hidefumi; Fujii, Hiroshi; Yonekura, Shinichi*;
    NUTRITION RESEARCH AND PRACTICE, 13(1), 64-69, Feb. 2019WebofScience電子ジャーナル
  • 骨格筋分化の制御に寄与するIRE1-XBP1の機能解明
    徳武 優佳子;山田 啓太;林 聡子;坂田 章太郎;米倉 真一
    栄養生理研究会報 = Reviews on Animal Nutrition and Metabolism, 63(1), 15-22, 2019リポジトリ
  • The unfolded protein response is involved in both differentiation and apoptosis of bovine mammary epithelial cells
    Yonekura, Shinichi*; Tsuchiya, Megumi; Tokutake, Yukako; Mizusawa, Moeko; Nakano, Miwa; Miyaji, Makoto; Ishizaki, Hiroshi; Haga, Satoshi;
    JOURNAL OF DAIRY SCIENCE, 101(4), 3568-3578, Apr. 2018WebofScience電子ジャーナル
  • The role of unfolded protein response in differentiation of mammary epithelial cells
    Tsuchiya, Megumi; Koizumi, Yumiko; Hayashi, Satoko; Hanaoka, Miyuki; Tokutake, Yukako; Yonekura, Shinichi*
    Biochemical and biophysical research communications, 484(4), 903-908, 2017WebofScience電子ジャーナル
  • Subcellular Localization and Polymorphism of Bovine FABP4 in Bovine Intramuscular Adipocytes
    Yonekura, Shinichi*; Hirota, Shohei; Miyazaki, Honami; Tokutake, Yukako;
    ANIMAL BIOTECHNOLOGY, 27(2), 96-103, 2016WebofScience電子ジャーナル
  • Soluble extract of soybean fermented with Aspergillus oryzae GB 107 inhibits fat accumulation in cultured 3T3-L1 adipocytes
    So, Kyoung-Ha; Suzuki, Yasuki; Yonekura, Shinichi; Suzuki, Yutaka; Lee, Chan Ho; Kim, Sung Woo; Katoh, Kazuo; Roh, Sang-Gun;
    NUTRITION RESEARCH AND PRACTICE, 9(4), 439-444, Aug. 2015WebofScience電子ジャーナル
  • ALS-Linked P56S-VAPB Mutation Impairs the Formation of Multinuclear Myotube in C2C12 Cells
    Tokutake, Yukako; Yamada, Keita; Ohata, Masaki; Obayashi, Yoshihito; Tsuchiya, Megumi; Yonekura, Shinichi*
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 16(8), 18628-18641, Aug. 2015WebofScience電子ジャーナル
  • Inhibitory/Suppressive Oligodeoxynucleotide Nanocapsules as Simple Oral Delivery Devices for Preventing Atopic Dermatitis in Mice
    Wang, Yeqin; Yamamoto, Yoshinari; Shigemori, Suguru; Watanabe, Takafumi; Oshiro, Kazushi; Wang, Xinyu; Wang, Pengfei; Sato, Takashi; Yonekura, Shinichi; Tanaka, Sachi; Kitazawa, Haruki; Shimosato, Takeshi;
    MOLECULAR THERAPY, 23(2), 297-309, Feb. 2015WebofScience電子ジャーナル
  • ALS-associated P56S-VAPB mutation restrains 3T3-L1 preadipocyte differentiation
    Tokutake, Yukako; Gushima, Kazunari; Miyazaki, Honami; Shimosato, Takeshi; Yonekura, Shinichi*
    Biochemical and biophysical research communications, 460(3), 831-837, 2015WebofScience電子ジャーナル
  • Effect of single nucleotide polymorphisms in GH gene promoter region on carcass traits and intramuscular fatty acid compositions in Japanese Black cattle
    Sugita, Haruna; Ardiyanti, Astrid; Yokota, Shoko; Yonekura, Shinichi; Hirayama, Takuji; Shoji, Noriaki; Yamauchi, Eri; Suzuki, Keiichi; Katoh, Kazuo; Roh, Sang-Gun;
    LIVESTOCK SCIENCE, 165, 15-21, Jul. 2014WebofScience電子ジャーナル
  • Histological analysis of glucagon-like peptide-1 receptor expression in chicken pancreas
    Watanabe, Takafumi; Nishimura, Kei; Hosaka, Yoshinao Z.; Shimosato, Takeshi; Yonekura, Shinichi; Suzuki, Daisuke; Takemoto, Chihiro; Monir, Mohammad Moniruzzaman; Hiramatsu, Kohzy;
    CELL AND TISSUE RESEARCH, 357(1), 55-61, Jul. 2014WebofScience電子ジャーナル
  • Influences of protein ingestion on glucagon-like peptide (GLP)-1-immunoreactive endocrine cells in the chicken ileum
    Monir, Mohammad M.; Hiramatsu, Kohzy; Matsumoto, Sachiko; Nishimura, Kei; Takemoto, Chihiro; Shioji, Tomomi; Watanabe, Takafumi; Kita, Kazumi; Yonekura, Shinichi; Roh, Sang Gun
    ANIMAL SCIENCE JOURNAL, 85(5), 581-587, May 2014WebofScienceリポジトリ電子ジャーナル
  • Dexamethasone and Acetate Modulate Cytoplasmic Leptin in Bovine Preadipocytes
    Yonekura, Shinichi*; Hirota, Shohei; Tokutake, Yukako; Rose, Michael T.; Katoh, Kazuo; Aso, Hisashi
    ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 27(4), 567-573, Apr. 2014WebofScience電子ジャーナル
  • Proliferating bovine intramuscular preadipocyte cells synthesize leptin
    Yonekura, S*.; Tokutake, Y.; Hirota, S.; Rose, M. T.; Katoh, K.; Aso, H.
    DOMESTIC ANIMAL ENDOCRINOLOGY, 45(1), 33-37, Jul. 2013WebofScience電子ジャーナル
  • Expression of the immunoreactive buckwheat major allergenic storage protein in Lactococcus lactis
    Shigemori, Suguru; Yonekura, Shinichi; Sato, Takashi; Otani, Hajime; Shimosato, Takeshi
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 97(8), 3603-3611, Apr. 2013WebofScience電子ジャーナル
  • Expression of a Biologically Active GFP-alpha(S1)-Casein Fusion Protein in Lactococcus lactis
    Shigemori, Suguru; Yonekura, Shinichi; Sato, Takashi; Nakanishi, Maya; Otani, Hajime; Shimosato, Takeshi
    CURRENT MICROBIOLOGY, 64(6), 569-575, Jun. 2012WebofScience電子ジャーナル
  • AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in Notch signaling during eye development in Drosophila melanogaster
    Kametaka, Satoshi; Kametaka, Ai; Yonekura, Shinichi; Haruta, Mineyuki; Takenoshita, Seiichi; Goto, Satoshi; Waguri, Satoshi
    JOURNAL OF CELL SCIENCE, 125(3), 634-648, 01 Feb. 2012WebofScience電子ジャーナル
  • Conserved Alternative Splicing and Expression Patterns of Arthropod N-Cadherin
    Hsu, Shu-Ning; Yonekura, Shinichi; Ting, Chun-Yuan; Robertson, Hugh M.; Iwai, Youichi; Uemura, Tadashi; Lee, Chi-Hon; Chiba, Akira
    PLOS GENETICS, 5(4), Apr. 2009WebofScience電子ジャーナル
  • Tiling of R7 axons in the Drosophila visual system is mediated both by transduction of an activin signal to the nucleus and by mutual repulsion
    Ting, Chun-Yuan; Herman, Tory; Yonekura, Shinichi; Gao, Shuying; Wang, Jian; Serpe, Mihaela; O'Connor, Michael B.; Zipursky, S. Lawrence; Lee, Chi-Hon
    NEURON, 56(5), 793-806, 06 Dec. 2007WebofScience電子ジャーナル
  • Alternative splicing expands spatiotemporal expression complexity of arthropod N-Cadherin
    Hsu, Shu-Ning; Yonekura, Shinichi; Ting, Chun-Yuan; Robertson, Hugh M.; Lee, Chi-Hon; Chiba, Akira
    DEVELOPMENTAL BIOLOGY, 306(1), 376-376, 01 Jun. 2007WebofScience電子ジャーナル
  • Adhesive but not signaling activity of Drosophila N-cadherin is essential for target selection of photoreceptor afferents
    Yonekura, Shinichi; Xu, Lei; Ting, Chun-Yuan; Lee, Chi-Hon
    DEVELOPMENTAL BIOLOGY, 304(2), 759-770, 15 Apr. 2007WebofScience電子ジャーナル
  • The variable transmembrane domain of Drosophila N-cadherin regulates adhesive activity
    Yonekura, Shinichi; Ting, Chun-Yuan; Neves, Guilherme; Hung, Kimberly; Hsu, Shu-ning; Chiba, Akira; Chess, Andrew; Lee, Chi-Hon
    MOLECULAR AND CELLULAR BIOLOGY, 26(17), 6598-6608, Sep. 2006WebofScience電子ジャーナル
  • Growth hormone and lactogenic hormones can reduce the leptin mRNA expression in bovine mammary epithelial cells
    Yonekura, S; Sakamoto, K; Komatsu, T; Hagino, A; Katoh, K; Obara, Y
    DOMESTIC ANIMAL ENDOCRINOLOGY, 31(1), 88-96, Jul. 2006WebofScience電子ジャーナル
  • Drosophila N-cadherin functions in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents
    Ting, CY*; Yonekura, S*; Chung, P; Hsu, SN; Robertson, HM; Chiba, A; Lee, CH. *contributed equally to this work.
    DEVELOPMENT, 132(5), 953-963, Mar. 2005WebofScience電子ジャーナル
  • Octanoate stimulates cytosolic triacylglycerol accumulation and CD36 mRNA expression but inhibits Acetyl coenzyme A carboxylase activity in primary cultured bovine mammary epithelial cells
    Yonezawa, T; Yonekura, S; Sanosaka, M; Hagino, A; Katoh, K; Obara, Y
    JOURNAL OF DAIRY RESEARCH, 71(4), 398-404, Nov. 2004WebofScience電子ジャーナル
  • Effects of long-chain fatty acids on cytosolic triacylglycerol accumulation and lipid droplet formation in primary cultured bovine mammary epithelial cells
    Yonezawa, T; Yonekura, S; Kobayashi, Y; Hagino, A; Katoh, K; Obara, Y
    JOURNAL OF DAIRY SCIENCE, 87(8), 2527-2534, Aug. 2004WebofScience
  • Suppressing effects of bisphenol A on the secretory function of ovine anterior pituitary cells
    Katoh, K; Matsuda, A; Ishigami, A; Yonekura, S; Ishiwata, H; Chen, C; Obara, Y
    CELL BIOLOGY INTERNATIONAL, 28(6), 463-469, 2004WebofScience電子ジャーナル
  • Effects of acetate and butyrate on the expression of leptin and short-form leptin receptor in bovine and rat anterior pituitary cells
    Yonekura, S; Senoo, T; Kobayashi, Y; Yonezawa, T; Katoh, K; Obara, Y
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 133(2), 165-172, Sep. 2003WebofScience電子ジャーナル
  • In vitro differentiation of a cloned bovine mammary epithelial cell
    Rose, MT; Aso, H; Yonekura, S; Komatsu, T; Hagino, A; Ozutsumi, K; Obara, Y
    JOURNAL OF DAIRY RESEARCH, 69(3), 345-355, Aug. 2002WebofScience電子ジャーナル
  • Effects of nutritional conditions around weaning on carbonic anhydrase activity in the parotid gland and ruminal and abomasal epithelia of Holstein calves
    Kitade, K; Takahashi, K; Yonekura, S; Katsumata, N; Furukawa, G; Ohsuga, S; Nishita, T; Katoh, K; Obara, Y
    JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY, 172(5), 379-385, Jul. 2002WebofScience電子ジャーナル
  • Effects of aging and weaning on mRNA expression of leptinand CCK receptors in the calf rumen and abomasum
    Yonekura, S; Kitade, K; Furukawa, G; Takahashi, K; Katsumata, N; Katoh, K; Obara, Y
    DOMESTIC ANIMAL ENDOCRINOLOGY, 22(1), 25-35, Mar. 2002WebofScience
  • Relationship between serum leptin concentrations and the marbling scores in Japanese Black Cattle.
    Yonekura S, Kitade K, Furukawa G, Takahashi K, Katsumata N, Katoh K, Obara Y.
    Anim Sci J, 22, 25-35, 2002
  • Effects of adenosine 5'-triphosphate and growth hormone on cellular H+ transport and calcium ion concentrations in cloned bovine mammary epithelial cells
    Katoh, K; Komatsu, T; Yonekura, S; Ishiwata, H; Hagino, A; Obara, Y
    JOURNAL OF ENDOCRINOLOGY, 169(2), 381-388, May 2001WebofScience

Books and other publications

  • 新編 家畜生理学
    加藤和雄・古瀬充宏・盧尚建・山崎淳・佐野宏明・麻生久・野地智法・米倉真一・萩野顕彦・林英明
    養賢堂, 2015

Affiliated academic society

  • 北信越畜産学会
  • The Molecular Biology Society of Japan
  • Japanese Society of Animal Science
  • American Dairy Science Association

Research Themes

  • 乳腺の小胞体ストレス応答機構に着眼した泌乳制御機序解明と泌乳平準化研究への新展開
    科学研究費補助金, 基盤研究(B)
    2020 - 2022
  • 小胞体ストレス応答機構に着目した筋肥大化メカニズムの解明
    科学研究費補助金, 基盤研究(C)
    2017 - 2019
  • Elucidation of the intracellular mechanism related to milk yield of mammary epithelial cells
  • Elucidation of in vivo mechanisms associated with perinatal diseases in dairy cows
  • Molecular mechanisms regulating myogenic determination and differentiation.