信州大学HOMEENGLISH交通・キャンパス案内

研究者総覧研究者総覧

研究者、研究内容などで検索
項目別検索はこちら

齋藤 章治  サイトウ ショウジ

教員組織学術研究院(医学系)電話番号
教育組織医学部附属病院 小児科FAX番号
職名講師メールアドレス
住所〒390-8621 長野県松本市旭3-1-1ホームページURL

更新日:2022/04/12

プロフィール

研究分野
小児科学
血液内科学
免疫学
キーワード:小児科学 , 血液学 , がん免疫療法
所属学会
所属学会
国際小児がん学会
日本小児科学会
日本血液学会
小児血液・がん学会
米国遺伝子細胞治療学会
日本造血・免疫療法学会
日本輸血・細胞治療学会
米国血液学会
学歴
取得学位
医学博士 , 信州大学大学院
医学修士 , 信州大学
研究職歴等
研究職歴
2019- , 信州大学医学部 講師
2018-2018 , 信州大学医学部 助教
2014-2016 , ベイラー医科大学 ポストドクトラルアソシエイツ
2013-2013 , 信州大学医学附附属病院 先端細胞治療センター信州大学医学附附属病院 先端細胞治療センター信州大学医学部附属病院 助教(診療)

留学歴
2014-2016 , ベイラー医科大学 遺伝子細胞治療センター

研究活動業績

研究業績(著書・
発表論文等)
論文
Impact of acute kidney injury on overall survival in children and young adults undergoing allogeneic hematopoietic stem cell transplantation
PEDIATRIC BLOOD & CANCER,68(9) 2021(Sep.)
Author:Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Nakazawa, Yozo;
Keywords:acute kidney injury; allo-HSCT; malignant; nonmalignant; overall survival;


Investigation of risk factors associated with erythrocyte engraftment after ABO-incompatible hematopoietic stem cell transplantation
CLINICAL TRANSPLANTATION,35(6) 2021(Jun.)
Author:Yanagisawa, Ryu; Nakazawa, Hideyuki; Nishina, Sayaka; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Nakazawa, Yozo;
Keywords:ABO blood type; cytomegalovirus; HLA antibody; immunohematology; isoagglutinin;


Mutated GM-CSF-based CAR-T cells targeting CD116/CD131 complexes exhibit enhanced anti-tumor effects against acute myeloid leukaemia
CLINICAL & TRANSLATIONAL IMMUNOLOGY,10(5) 2021
Author:Hasegawa, Aiko; Saito, Shoji; Narimatsu, Shogo; Nakano, Shigeru; Nagai, Mika; Ohnota, Hideki; Inada, Yoichi; Morokawa, Hirokazu; Nakashima, Ikumi; Morita, Daisuke; Ide, Yuichiro; Matsuda, Kazuyuki; Tashiro, Haruko; Yagyu, Shigeki; Tanaka, Miyuki; Nakazawa, Yozo;
Keywords:AML; CD116; GM-CSF; GM-CSF receptor; GMR; low affinity;


A lymphodepleted non-human primate model for the assessment of acute on-target and off-tumor toxicity of human chimeric antigen receptor-T cells
CLINICAL & TRANSLATIONAL IMMUNOLOGY,10(6) 2021
Author:Yagyu, Shigeki; Mochizuki, Hidemi; Yamashima, Kumiko; Kubo, Hiroshi; Saito, Shoji; Tanaka, Miyuki; Sakamoto, Kengo; Shimoi, Akihito; Nakazawa, Yozo;
Keywords:CAR-T cells; cell therapy; lymphodepletion; non-human primate; off-target toxicity; on-target toxicity;


Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients
PEDIATRIC BLOOD & CANCER,67(12) 2020(Dec.)
Author:Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Hidaka, Yoshihiko; Nakazawa, Yozo;
Keywords:allo-HSCT; estimated GFR; inulin clearance;


Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,111(5):702-710 2020(May)
Author:Shigemura, Tomonari; Sakashita, Kazuo; Okura, Eri; Morita, Daisuke; Komori, Kazutoshi; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo;


Thyroid tumor surveillance using ultrasound in childhood cancer survivors
PEDIATRICS INTERNATIONAL,62(5):562-568 2020(May)
Author:Furui, Yu; Morita, Daisuke; Okura, Eri; Komori, Kazutoshi; Saito, Shoji; Hirabayashi, Kanae; Tanaka, Miyuki; Nakazawa, Yozo;


Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report
PEDIATRIC BLOOD & CANCER,67(4) 2020(Apr.)
Author:Morota, Haruka; Saito, Shoji; Uchida, Eriko; Okura, Eri; Matsuoka, Daisuke; Hidaka, Yoshihiko; Natsume, Takenori; Watanabe, Tatsuo; Shigemura, Tomonari; Morita, Daisuke; Tanaka, Miyuki; Kurata, Takashi; Sakashita, Kazuo; Nakazawa, Yozo;


Multiple heterogeneous bone invasions of B lymphoblastic lymphoma with the TCF3/PBX1 fusion gene: a case report
INTERNATIONAL JOURNAL OF HEMATOLOGY,111(2):163-165 2020(Feb.)
Author:Okura, Eri; Saito, Shoji; Natsume, Takenori; Morita, Daisuke; Tanaka, Miyuki; Kiyokawa, Nobutaka; Nakazawa, Yozo;


Prophylactic piperacillin administration in pediatric patients with solid tumors following different intensities of chemotherapy
PEDIATRICS INTERNATIONAL,62(2):158-168 2020(Feb.)
Author:Saito, Shoji; Yanagisawa, Ryu; Minami, Kisei; Uchida, Eriko; Watanabe, Tatsuo; Komori, Kazutoshi; Kurata, Takashi; Nakamura, Tomohiko; Sakashita, Kazuo;


Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
LEUKEMIA & LYMPHOMA,61(4):967-970 2020
Author:Saito, Shoji; Taira, Chiaki; Matsuda, Kazuyuki; Yanagisawa, Ryu; Morita, Daisuke; Shigemura, Tomonari; Yoshikawa, Kentaro; Tanaka, Miyuki; Sakashita, Kazuo; Mukai, Saki; Shimodaira, Shigetaka; Koike, Kenichi; Nakazawa, Yozo;


Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
PEDIATRIC TRANSPLANTATION,23(3) 2019(May)
Author:Komori, Kazutoshi; Hirabayashi, Koichi; Morita, Daisuke; Hara, Yosuke; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;


Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
PEDIATRIC TRANSPLANTATION,23(3) 2019(May)
Author:Komori, Kazutoshi; Hirabayashi, Koichi; Morita, Daisuke; Hara, Yosuke; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;


Evaluation of the Safety and Efficacy of piggyBac Transposon-Mediated Chimeric Antigen Receptor T Cells Using a Non-Human Primate Model
MOLECULAR THERAPY,27(4):408-408 2019
Author:Morokawa, Hirokazu; Tanaka, Miyuki; Saito, Shoji; Shimoi, Akihito; Yagyu, Shigeki; Nakazawa, Yozo;


Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
PRACTICAL RADIATION ONCOLOGY,9(5):333-337 2019
Author:Komori, Kazutoshi; Saito, Shoji; Araya, Masayuki; Morita, Daisuke; Kurata, Takashi; Hirabayashi, Koichi; Tanaka, Miyuki; Koiwai, Keiichiro; Tauchi, Katsunori; Masaki, Hidekazu; Nakazawa, Yozo;


Evaluation of the Safety and Efficacy of piggyBac Transposon-Mediated Chimeric Antigen Receptor T Cells Using a Non-Human Primate Model
MOLECULAR THERAPY,27(4):408-408 2019
Author:Morokawa, Hirokazu; Tanaka, Miyuki; Saito, Shoji; Shimoi, Akihito; Yagyu, Shigeki; Nakazawa, Yozo;


CAR-T 療法の現状と今後の展望
信州医学雑誌,66(6):425-433 2018(Dec. 10)
Author:齋藤章治 中沢洋三


Multiple Internal Jugular Vein Thromboses in a Patient With Localized Rhabdomyosarcoma
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,40(8):628-629 2018(Nov.)
Author:Uchida, Eriko; Saito, Shoji; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo;


Lymphadenopathy with coexisting normal architecture in malignant lymphoma
INTERNATIONAL JOURNAL OF HEMATOLOGY,108(5):463-464 2018(Nov.)
Author:Saito, Shoji; Ogiso, Yoshifumi; Sakashita, Kazuo;


Combining Oncolytic Viruses with CAR-T Cells for the Treatment of Solid Tumors
PEDIATRIC BLOOD & CANCER,65:S13-S14 2018(Nov.)
Author:Saito, Shoji;


Multiple Internal Jugular Vein Thromboses in a Patient With Localized Rhabdomyosarcoma
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,40(8):628-629 2018(Nov.)
Author:Uchida, Eriko; Saito, Shoji; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo;


Lymphadenopathy with coexisting normal architecture in malignant lymphoma
INTERNATIONAL JOURNAL OF HEMATOLOGY,108(5):463-464 2018(Nov.)
Author:Saito, Shoji; Ogiso, Yoshifumi; Sakashita, Kazuo;


Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation
PEDIATRIC TRANSPLANTATION,22(6) 2018(Sep.)
Author:Yanagisawa, Toshimitsu; Saito, Shoji; Katsuyama, Yoshihiko; Hirabayashi, Koichi; Shigemura, Tomonari; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;


Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation
PEDIATRIC TRANSPLANTATION,22(6) 2018(Sep.)
Author:Yanagisawa, Toshimitsu; Saito, Shoji; Katsuyama, Yoshihiko; Hirabayashi, Koichi; Shigemura, Tomonari; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;


Radiation necrosis following proton therapy successfully treated by low-dose bevacizumab in a patient with relapsed anaplastic ependymoma
PEDIATRIC BLOOD & CANCER,65(8) 2018(Aug.)
Author:Saito, Shoji; Miyairi, Yosuke; Araya, Masayuki; Yomo, Shoji; Kuwabara, Haruki; Uchida, Eriko; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo; Shigeta, Hiroaki;


Radiation necrosis following proton therapy successfully treated by low-dose bevacizumab in a patient with relapsed anaplastic ependymoma
PEDIATRIC BLOOD & CANCER,65(8) 2018(Aug.)
Author:Saito, Shoji; Miyairi, Yosuke; Araya, Masayuki; Yomo, Shoji; Kuwabara, Haruki; Uchida, Eriko; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo; Shigeta, Hiroaki;


PiggyBac Transposon-Mediated CAR-T Cells Targeting GM-CSF Receptors Prolong the Survival of Mice Bearing Human Acute Myeloid Leukemia
MOLECULAR THERAPY,26(5):194-195 2018(May)
Author:Hasegawa, Aiko; Narimatsu, Shogo; Tanaka, Miyuki; Nagai, Mika; Morita, Daisuke; Saito, Shoji; Nakano, Shigeru; Onozato, Tomoya; Hayashi, Morimichi; Matsuda, Kazuyuki; Yanagisawa, Ryu; Ohnota, Hideki; Nakazawa, Yozo;


Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
ANTICANCER RESEARCH,38(4):2227-2234 2018(Apr.)
Author:Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;


Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
ANTICANCER RESEARCH,38(4):2227-2234 2018(Apr.)
Author:Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;


Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT,8:131-140 2018(Mar.)
Author:Morita, Daisuke; Nishio, Nobuhiro; Saito, Shoji; Tanaka, Miyuki; Kawashima, Nozomu; Okuno, Yusuke; Suzuki, Satoshi; Matsuda, Kazuyuki; Maeda, Yasuhiro; Wilson, Matthew H.; Dotti, Gianpietro; Rooney, Cliona M.; Takahashi, Yoshiyuki; Nakazawa, Yozo;


Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,39(3):E150-E154 2017(Apr.)
Author:Tanaka, Miyuki; Kamata, Takahiro; Yanagisawa, Ryu; Morita, Daisuke; Saito, Shoji; Sakashita, Kazuo; Shiohara, Masaaki; Kurita, Hiroshi; Koike, Kenichi; Nakazawa, Yozo;


Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia
PEDIATRICS AND NEONATOLOGY,58(1):81-84 2017(Feb.)
Author:Hirabayashi, Koichi; Takatsuki, Mitsuho; Motobayashi, Mitsuo; Kurata, Takashi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Ishizone, Satoshi; Ota, Hiroyoshi; Koike, Kenichi;


Catheter-Related Bacteremia Due to Gordonia sputi in a Patient with Acute Lymphocytic Leukemia: a Case Report
JAPANESE JOURNAL OF INFECTIOUS DISEASES,69(4):342-343 2016(Jul.)
Author:Negishi, Tatsuya; Matsumoto, Takehisa; Saito, Shoji; Kasuga, Eriko; Horiuchi, Kazuki; Natori, Tatsuya; Takehara, Kenta; Sugano, Mitsutoshi; Honda, Takayuki;


Clinical and Laboratory Outcomes After Umbilical Cord Blood Transplantation in a Patient with Mucolipidosis II Alpha/Beta
AMERICAN JOURNAL OF MEDICAL GENETICS PART A,170(5):1278-1282 2016(May)
Author:Shibazaki, Takumi; Hirabayashi, Koichi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Takagi, Mineo; Shiohara, Masaaki; Adachi, Kaori; Nanba, Eiji; Sakai, Norio; Koike, Kenichi;


Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction
PEDIATRIC BLOOD & CANCER,63(4):709-711 2016(Apr.)
Author:Hirabayashi, Koichi; Kurata, Takashi; Horiuchi, Kazuki; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;


Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review
INTERNATIONAL JOURNAL OF HEMATOLOGY,103(1):107-111 2016(Jan.)
Author:Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Saito, Shoji; Tanaka, Miyuki; Shiohara, Masaaki; Shimodaira, Shigetaka; Koike, Kenichi;


GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies
HAEMATOLOGICA,100(10):E398-E401 2015(Oct.)
Author:Wang, Xinan; Muramatsu, Hideki; Okuno, Yusuke; Sakaguchi, Hirotoshi; Yoshida, Kenichi; Kawashima, Nozomu; Xu, Yinyan; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Saito, Shoji; Nakazawa, Yozo; Masunari, Taro; Hirose, Tadashi; Elmahdi, Shaimaa; Narita, Atsushi; Doisaki, Sayoko; Ismael, Olfat; Makishima, Hideki; Hama, Asahito; Miyano, Satoru; Takahashi, Yoshiyuki; Ogawa, Seishi; Kojima, Seiji;


Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature
CYTOTHERAPY,17(3):330-335 2015(Mar.)
Author:Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;


Successful treatment for West syndrome with severe combined immunodeficiency
BRAIN & DEVELOPMENT,37(1):140-144 2015(Jan.)
Author:Motobayashi, Mitsuo; Inaba, Yuji; Fukuyama, Tetsuhiro; Kurata, Takashi; Niimi, Taemi; Saito, Shoji; Shiba, Naoko; Nishimura, Takafumi; Shigemura, Tomonari; Nakazawa, Yozo; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Ichikawa, Motoki; Koike, Kenichi;


Evaluation of Mucorales DNA load in cerebrospinal fluid in a patient with possible cerebral mucormycosis treated with intravenous liposomal amphotericin B
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES,29:200-202 2014(Dec.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Motobayashi, Mitsuo; Saito, Shoji; Koike, Kenichi;


Anti-leukemic potency of piggyBac-mediated CD 19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
CYTOTHERAPY,16(9):1257-1269 2014(Sep.)
Author:Saito, Shoji; Nakazawa, Yozo; Sueki, Akane; Matsuda, Kazuyuki; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Sato, Yuko; Okabe, Seiichi; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooney, Cliona M.; Koike, Kenichi;


Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation
INTERNATIONAL JOURNAL OF HEMATOLOGY,100(2):206-209 2014(Aug.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Sano, Kenji; Yaguchi, Takashi; Motobayashi, Mitsuo; Saito, Shoji; Noda, Shunsuke; Kobayashi, Norimoto; Agematsu, Kazunaga; Honda, Takayuki; Koike, Kenichi;


Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia
LEUKEMIA,28(7):1545-1548 2014(Jul.)
Author:Matsuda, K; Nakazawa, Y; Iwashita, C; Kurata, T; Hirabayashi, K; Saito, S; Tanaka, M; Yoshikawa, K; Yanagisawa, R; Sakashita, K; Sasaki, S; Honda, T; Koike, K


Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies
INTERNATIONAL JOURNAL OF HEMATOLOGY,99(4):477-486 2014(Apr.)
Author:Hirabayashi, Kanae; Nakazawa, Yozo; Matsuura, Hiroki; Hara, Yosuke; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi;


Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis
TRANSFUSION,54(3):516-521 2014(Mar.)
Author:Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Kentaro; Hirabayashi, Koichi; Saito, Shoji; Kobayashi, Norimoto; Sakashita, Kazuo; Shiohara, Masaaki; Wada, Taizo; Shimodaira, Shigetaka; Agematsu, Kazunaga; Koike, Kenichi;


Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
SCIENTIFIC REPORTS,4 2014
Author:Hirabayashi, Koichi; Nakazawa, Yozo; Sakashita, Kazuo; Kurata, Takashi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;


Usefulness of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission for Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm With Skin Involvement: A Case Report and Review of Literature
PEDIATRIC BLOOD & CANCER,60(11):E140-E142 2013(Nov.)
Author:Sakashita, Kazuo; Saito, Shoji; Yanagisawa, Ryu; Tanaka, Miyuki; Yoshikawa, Kentaro; Hirabayashi, Koichi; Tsukahara, Keiko; Motobayashi, Mitsuo; Nakazawa, Yozo; Koike, Kenichi;


Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients
TRANSFUSION,53(9):2053-2060 2013(Sep.)
Author:Yanagisawa, Ryu; Shimodaira, Shigetaka; Kojima, Shunsuke; Nakasone, Nobuhiko; Ishikawa, Shinsuke; Momose, Kayo; Honda, Takayuki; Yoshikawa, Kentaro; Saito, Shoji; Tanaka, Miyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Akino, Mitsuaki; Hirayama, Junichi; Azuma, Hiroshi; Koike, Kenichi;


Recipient seropositivity for adenovirus type 11 (AdV11) is a highly predictive factor for the development of AdV11-induced hemorrhagic cystitis after allogeneic hematopoietic SCT.
Bone Marrow Transplant.,May;48(5):737-9 2013(May)
Author:23. Nakazawa Y, Saito S, Yanagisawa R, Suzuki T, Ito T, Ishida F, Muramatsu H, Matsumoto K, Kato K, Ishida H, Umeda K, Adachi S, Nakahata T, Koike K.


Food allergy after cord blood transplantation in children
BRITISH JOURNAL OF HAEMATOLOGY,158(5):672-676 2012(Sep.)
Author:Sakashita, Kazuo; Nakazawa, Yozo; Yanagisawa, Ryu; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Hirabayashi, Koichi; Kusakari, Mai; Kato, Sawako; Hidaka, Nao; Nakayama, Yoshiko; Shigemura, Tomonari; Kobayashi, Norimoto; Kobayashi, Mikiko; Shiohara, Masaaki; Koike, Kenichi;


Critical Illness Polyneuropathy and Myopathy Caused by Bacillus Cereus Sepsis in Acute Lymphoblastic Leukemia
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,34(3):E110-E113 2012(Apr.)
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Suzuki, Takefumi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;


Application of allele-specific quantitative PCR using genomic DNA to monitor minimal residual disease based on mutant gene levels following allogeneic hematopoietic stem cell transplantation in patients with hematological malignancies: Comparison of mutant levels with autologous DNA percentage by short tandem repeat-PCR
CLINICA CHIMICA ACTA,413(3-4):516-519 2012
Author:Taira, Chiaki; Matsuda, Kazuyuki; Saito, Shoji; Sakashita, Kazuo; Sugano, Mitsutoshi; Okumura, Nobuo; Honda, Takayuki;


Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
LEUKEMIA RESEARCH,35(12):1578-1584 2011(Dec.)
Author:Saito, Shoji; Matsuda, Kazuyuki; Taira, Chiaki; Sano, Kenji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;


Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome
LEUKEMIA & LYMPHOMA,52(8):1523-1527 2011(Aug.)
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Takahashi, Daijiro; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Nakamura, Tomohiko; Ishii, Eizaburo; Koike, Kenichi;


Disappearance of Minimal Residual Disease After the Early Withdrawal of Immunosuppressants in a Patient With Juvenile Myelomonocytic Leukemia
PEDIATRIC BLOOD & CANCER,56(3):501-502 2011(Mar.)
Author:Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Nakazawa, Yozo; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;


Increased pretransplant QT dispersion as a risk factor for the development of cardiac complications during and after preparative conditioning for pediatric allogeneic hematopoietic stem cell transplantation
PEDIATRIC TRANSPLANTATION,14(8):986-992 2010(Dec.)
Author:Motoki, Noriko; Shimizu, Takashi; Akazawa, Yohei; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Motoki, Hirohiko; Nakazawa, Yozo; Sakashita, Kazuo; Iwasaki, Yasushi; Shiohara, Masaaki; Koike, Kenichi;


Polymyxin-Direct Hemoperfusion for Sepsis-Induced Multiple Organ Failure
PEDIATRIC BLOOD & CANCER,55(1):202-205 2010
Author:Hirabayashi, Koichi; Shiohara, Masaaki; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;


Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
BLOOD,115(26):5429-5431 2010
Author:Matsuda, Kazuyuki; Taira, Chiaki; Sakashita, Kazuo; Saito, Shoji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Fukushima, Keitaro; Oda, Megumi; Honda, Takayuki; Nakahata, Tatsutoshi; Koike, Kenichi;


Ela2 Mutations and Clinical Manifestations in Familial Congenital Neutropenia
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY,31(5):319-324 2009(May)
Author:Shiohara, Masaaki; Shigemura, Tomonari; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Asada, Hiroshi; Ishii, Eizaburo; Koike, Kazutoshi; Chin, Motoaki; Kobayashi, Masao; Koike, Kenichi;


Bilateral Perisylvian Polymicrogyria, Periventricular Nodular Heterotopia, and Left Ventricular Noncompaction in a Girl With 10.5-11.1 Mb Terminal Deletion of 1p36
AMERICAN JOURNAL OF MEDICAL GENETICS PART A,146A(22):2891-2897 2008
Author:Saito, Shoji; Kawamura, Rie; Kosho, Tomoki; Shimizu, Takashi; Aoyama, Koki; Koike, Kenichi; Wada, Takahito; Matsumoto, Naotnichi; Kato, Mitsuhiro; Wakui, Keiko; Fukushima, Yoshimitsu;


CD30+anaplastic large cell lymphoma complicated by pyoderma gangrenosum with increased levels of serum cytokines
EUROPEAN JOURNAL OF HAEMATOLOGY,77(3):251-254 2006(Sep.)
Author:Saito, Shoji; Yasui, Kozo; Hosoda, Waki; Ogawa, Mina; Kobayashi, Norimoto; Sakashita, Kazuo; Koike, Kenichi;


講演・口頭発表等
Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
ASGCT 23rd Annual Meeting 2020(May 12)
Presenter:Shoji Saito, Ikumi Nakashima, Aiko Hasegawa, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Shigeki Yagyu, and Yozo Nakazawa


Mutated GM-CSF-Based CAR T-Cells Targeting CD116/CD131 Complexes Exhibit Enhanced Anti-Tumor Effects Against Acute Myeloid Leukemia
62nd Annual Meeting and Exposition of American Society of Hematology 2020
Presenter:Saito S, Hasegawa A, Nagai M, Inada Y, Morokawa H, Nakashima I, Morita D, Ide Y, Matsuda K, Tashiro H, Yagyu S, Tanaka M, Nakazawa Y


PiggyBac-modified GM-CSF receptor-specific CAR-T therapy for acute myeloid leukemia.
第82回日本血液学会学術集会 2020
Presenter:Saito S, Hasegawa A, Tanaka M, Morita D, Nakashima I, Morokawa H, Nagai M, Inada Y, Matsuda K, Ide Y, Tashiro H, Yagyu S, Tanaka M, Nakazawa Y


Tumor-tropic liposome-mediated therapeutic delivery of mRNA for pediatric / adolescent and young adult cancers
第79回日本癌学会学術集会 2020
Presenter:Saito S, Nakashima I, Hasegawa A, Akahshi E, Ishihara-Sugano M, Yagyu S, Nakazawa Y


Combining oncolytic viruses with CAR-T cells for the treatment of solid tumors
第60回小児血液・がん学会学術集会 2018(Nov. 15)
Presenter:齋藤章治


臍帯血移植にて長期寛解を維持しているX連鎖リンパ増殖症 type 2の 1例
第55回日本小児血液・がん学会学術集会 2013(Dec. 01)
Presenter:齋藤章治 中沢洋三 重村倫成 平林耕一 倉田敬 坂下一夫 小池健一 金兼弘和


WT1抗原特異的アロ樹状細胞療法によって長期寛解が得られた難治性急性リンパ性白血病の1例
第75回日本血液学会学術集会20 2013(Oct. 11)
Presenter:齋藤章治、田中美幸、柳沢龍、坂下一夫、吉川健太郎、倉田敬、平林耕一、中沢洋三、小池健一、下平滋隆


CD19-Specific T-Cell Therapy for Refractory Philadelphia-Chromosome-Positive Acute Lymphoblastic Leukemia Using PiggyBac Transposon-Based Gene Modification and Low Autoserum-Containing, but Xeno-Free and Tumor Cell Line-Free Culture System
MOLECULAR THERAPY 20 S184-S185 2012(May)
Presenter:Saito, Shoji; Nakazawa, Yozo; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooeny, Cliona M.; Koike, Kenichi;

研究費
科学研究費補助金(研究代表者)
2020 - 2022 , 治療遺伝子搭載ナノ粒子を用いた小児・AYA世代がんに対する革新的治療法の開発 , 基盤研究C
2018 - 2019 , 固形腫瘍に対する遺伝子改変T細胞と腫瘍溶解ウイルスによる複合免疫療法の開発 , 若手研究
2012 - 2013 , Ph陽性急性リンパ性白血病に対するCD19抗原特異的遺伝子改変T細胞療法の開発 , 若手研究(B)

その他公的資金
2019 - 2022 , がんに対する新規キメラ抗原受容体(CAR)-T細胞療法開発に関する国際共同研究