Hematology and medical oncology, hematology

2019
Assistant Professor, Shinshu University School of Medicine

2018 - 2018
Assistant Professor, Shinshu University School of Medicine

2014 - 2016
Postdoctral associates, Baylor Colloge of Medicine

2013 - 2013
Assistant professor

2014 - 2016, Cell & Gene Therapy, Baylor College of Medicine

Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group
Sato A, Hatta Y, Imai C, Oshima K, Okamoto Y, Deguchi T, Hashii Y, Fukushima T, Hori T, Kiyokawa N, Kato M, Saito S, Anami K, Sakamoto T, Kosaka Y, Suenobu S, Imamura T, Kada A, Saito AM, Manabe A, Kiyoi H, Matsumura I, Koh K, Watanabe A, Miyazaki Y, Horibe K.
Lancet Haematol, 10(6), e419-e432, Jun. 2023

Factors Affecting Day-to-Day Variations in Tacrolimus Concentration among Children and Young Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Maruyama Y, Maejima Y, Hirabayashi K, Morokawa H, Okura E, Saito S, Nakazawa Y.
Transplant Cell Ther, 29(4), 270.1-270.8, Apr. 2023

Basophil activation test for allergic and febrile non-haemolytic transfusion reactions among paediatric patients with haematological or oncological disease
Usami Y, Yanagisawa R, Kanai R, Ide Y, Konno S, Iwama M, Futatsugi A, Takeshita T, Furui Y, Komori K, Kurata T, Saito S, Tanaka M, Nakazawa Y, Sakashita K, Tozuka M.
Vox Sang, 118(1), 41-48, Jan. 2023

Non-viral inducible caspase 9 mRNA delivery using lipid nanoparticles against breast cancer: An in vitro study
Nakashima I, Saito S, Akahoshi E, Yagyu S, Sugano-Ishihara M, Nakazawa Y.
Biochem Biophys Res Commun, 20(635), 144-153, Dec. 2022
Corresponding

Impact of KIR-ligand mismatch on pediatric T-cell acute lymphoblastic leukemia in unrelated cord blood transplantation
Kawahara Y, Ishimaru S, Tanaka J, Kako S, Hirayama M, Kanaya M, Ishida H, Sato M, Kobayashi R, Kato M, Goi K, Saito S, Koga Y, Hashii Y, Kato K, Sato A, Atsuta Y, Sakaguchi H.
Transplant Cell Ther, 28(9), 598.1-598.8, Sep. 2022

Skin and soft tissue infections in adolescent chronic myeloid leukemia under dasatinib treatment
Uchida, Eriko; Saito, Shoji; Morita, Daisuke; Okura, Eri; Hirabayashi, Koichi; Tanaka, Miyuki; Nakazawa, Hideyuki; Minagawa, Akane; Nakazawa, Yozo;
Pediatric blood & cancer, 69(8), e29714, Aug. 2022, Refereed

Immature Platelet Fraction and Its Kinetics in Neonates
Kobayashi J, Takezawa Y, Saito S, Kubota N, Sakashita K, Nakazawa Y, Higuchi Y, Tozuka M, Ishida F.
J Pediatr Hematol Oncol, 45(2), e249-e253, May 2022

Relationship between allergic transfusion reactions and allergic predisposition among pediatric patients with hematological/oncological disease
Yanagisawa, Ryu; Ishimine, Nau; Komori, Kazutoshi; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Sakashita, Kazuo; Tozuka, Minoru; Nakazawa, Yozo;
TRANSFUSION, 2022, Refereed

Impact of acute kidney injury on overall survival in children and young adults undergoing allogeneic hematopoietic stem cell transplantation
Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Nakazawa, Yozo;
Pediatric blood & cancer, 68(9), Sep. 2021, Refereed

Investigation of risk factors associated with erythrocyte engraftment after ABO-incompatible hematopoietic stem cell transplantation
Yanagisawa, Ryu; Nakazawa, Hideyuki; Nishina, Sayaka; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Nakazawa, Yozo;
CLINICAL TRANSPLANTATION, 35(6), Jun. 2021, Refereed

A lymphodepleted non-human primate model for the assessment of acute on-target and off-tumor toxicity of human chimeric antigen receptor-T cells
Yagyu, Shigeki; Mochizuki, Hidemi; Yamashima, Kumiko; Kubo, Hiroshi; Saito, Shoji; Tanaka, Miyuki; Sakamoto, Kengo; Shimoi, Akihito; Nakazawa, Yozo;
Clinical & translational immunology, 10(6), 2021, Refereed

Mutated GM-CSF-based CAR-T cells targeting CD116/CD131 complexes exhibit enhanced anti-tumor effects against acute myeloid leukaemia
Hasegawa, Aiko; Saito, Shoji; Narimatsu, Shogo; Nakano, Shigeru; Nagai, Mika; Ohnota, Hideki; Inada, Yoichi; Morokawa, Hirokazu; Nakashima, Ikumi; Morita, Daisuke; Ide, Yuichiro; Matsuda, Kazuyuki; Tashiro, Haruko; Yagyu, Shigeki; Tanaka, Miyuki; Nakazawa, Yozo;
Clinical & translational immunology, 10(5), e1282, 2021, Refereed

Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients
Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Hidaka, Yoshihiko; Nakazawa, Yozo;
Pediatric blood & cancer, 67(12), Dec. 2020, Refereed

Thyroid tumor surveillance using ultrasound in childhood cancer survivors
Furui, Yu; Morita, Daisuke; Okura, Eri; Komori, Kazutoshi; Saito, Shoji; Hirabayashi, Kanae; Tanaka, Miyuki; Nakazawa, Yozo;
PEDIATRICS INTERNATIONAL, 62(5), 562-568, May 2020, Refereed

Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
Shigemura, Tomonari; Sakashita, Kazuo; Okura, Eri; Morita, Daisuke; Komori, Kazutoshi; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 111(5), 702-710, May 2020, Refereed

Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report
Morota, Haruka; Saito, Shoji; Uchida, Eriko; Okura, Eri; Matsuoka, Daisuke; Hidaka, Yoshihiko; Natsume, Takenori; Watanabe, Tatsuo; Shigemura, Tomonari; Morita, Daisuke; Tanaka, Miyuki; Kurata, Takashi; Sakashita, Kazuo; Nakazawa, Yozo;
Pediatric blood & cancer, 67(4), Apr. 2020, Refereed

Prophylactic piperacillin administration in pediatric patients with solid tumors following different intensities of chemotherapy
Saito, Shoji; Yanagisawa, Ryu; Minami, Kisei; Uchida, Eriko; Watanabe, Tatsuo; Komori, Kazutoshi; Kurata, Takashi; Nakamura, Tomohiko; Sakashita, Kazuo;
PEDIATRICS INTERNATIONAL, 62(2), 158-168, Feb. 2020, Refereed

Multiple heterogeneous bone invasions of B lymphoblastic lymphoma with the TCF3/PBX1 fusion gene: a case report
Okura, Eri; Saito, Shoji; Natsume, Takenori; Morita, Daisuke; Tanaka, Miyuki; Kiyokawa, Nobutaka; Nakazawa, Yozo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 111(2), 163-165, Feb. 2020, Refereed

Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
Saito, Shoji; Taira, Chiaki; Matsuda, Kazuyuki; Yanagisawa, Ryu; Morita, Daisuke; Shigemura, Tomonari; Yoshikawa, Kentaro; Tanaka, Miyuki; Sakashita, Kazuo; Mukai, Saki; Shimodaira, Shigetaka; Koike, Kenichi; Nakazawa, Yozo;
LEUKEMIA & LYMPHOMA, 61(4), 967-970, 2020, Refereed

Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
Komori, Kazutoshi; Hirabayashi, Koichi; Morita, Daisuke; Hara, Yosuke; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
PEDIATRIC TRANSPLANTATION, 23(3), May 2019, Refereed

Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
Komori, Kazutoshi; Hirabayashi, Koichi; Morita, Daisuke; Hara, Yosuke; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
PEDIATRIC TRANSPLANTATION, 23(3), May 2019, Refereed

Evaluation of the Safety and Efficacy of piggyBac Transposon-Mediated Chimeric Antigen Receptor T Cells Using a Non-Human Primate Model
Morokawa, Hirokazu; Tanaka, Miyuki; Saito, Shoji; Shimoi, Akihito; Yagyu, Shigeki; Nakazawa, Yozo;
MOLECULAR THERAPY, 27(4), 408-408, 2019, Refereed

Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
Komori, Kazutoshi; Saito, Shoji; Araya, Masayuki; Morita, Daisuke; Kurata, Takashi; Hirabayashi, Koichi; Tanaka, Miyuki; Koiwai, Keiichiro; Tauchi, Katsunori; Masaki, Hidekazu; Nakazawa, Yozo;
PRACTICAL RADIATION ONCOLOGY, 9(5), 333-337, 2019, Refereed

Evaluation of the Safety and Efficacy of piggyBac Transposon-Mediated Chimeric Antigen Receptor T Cells Using a Non-Human Primate Model
Morokawa, Hirokazu; Tanaka, Miyuki; Saito, Shoji; Shimoi, Akihito; Yagyu, Shigeki; Nakazawa, Yozo;
MOLECULAR THERAPY, 27(4), 408-408, 2019, Refereed

Chimeric Antigen Receptor (CAR)-T Cell Therapy
SAITO Shoji, NAKAZAWA Yozo
Shinshu Medical Journal, 66(6), 425-433, 10 Dec. 2018, Refereed

Lymphadenopathy with coexisting normal architecture in malignant lymphoma
Saito, Shoji; Ogiso, Yoshifumi; Sakashita, Kazuo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 108(5), 463-464, Nov. 2018, Refereed

Multiple Internal Jugular Vein Thromboses in a Patient With Localized Rhabdomyosarcoma
Uchida, Eriko; Saito, Shoji; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 40(8), 628-629, Nov. 2018, Refereed

Combining Oncolytic Viruses with CAR-T Cells for the Treatment of Solid Tumors
Saito, Shoji;
Pediatric blood & cancer, 65, S13-S14, Nov. 2018, Refereed

Lymphadenopathy with coexisting normal architecture in malignant lymphoma
Saito, Shoji; Ogiso, Yoshifumi; Sakashita, Kazuo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 108(5), 463-464, Nov. 2018, Refereed

Multiple Internal Jugular Vein Thromboses in a Patient With Localized Rhabdomyosarcoma
Uchida, Eriko; Saito, Shoji; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 40(8), 628-629, Nov. 2018, Refereed

Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation
Yanagisawa, Toshimitsu; Saito, Shoji; Katsuyama, Yoshihiko; Hirabayashi, Koichi; Shigemura, Tomonari; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;
PEDIATRIC TRANSPLANTATION, 22(6), Sep. 2018, Refereed

Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation
Yanagisawa, Toshimitsu; Saito, Shoji; Katsuyama, Yoshihiko; Hirabayashi, Koichi; Shigemura, Tomonari; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;
PEDIATRIC TRANSPLANTATION, 22(6), Sep. 2018, Refereed

Radiation necrosis following proton therapy successfully treated by low-dose bevacizumab in a patient with relapsed anaplastic ependymoma
Saito, Shoji; Miyairi, Yosuke; Araya, Masayuki; Yomo, Shoji; Kuwabara, Haruki; Uchida, Eriko; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo; Shigeta, Hiroaki;
Pediatric blood & cancer, 65(8), Aug. 2018, Refereed

Radiation necrosis following proton therapy successfully treated by low-dose bevacizumab in a patient with relapsed anaplastic ependymoma
Saito, Shoji; Miyairi, Yosuke; Araya, Masayuki; Yomo, Shoji; Kuwabara, Haruki; Uchida, Eriko; Watanabe, Tatsuo; Kurata, Takashi; Sakashita, Kazuo; Shigeta, Hiroaki;
Pediatric blood & cancer, 65(8), Aug. 2018, Refereed

PiggyBac Transposon-Mediated CAR-T Cells Targeting GM-CSF Receptors Prolong the Survival of Mice Bearing Human Acute Myeloid Leukemia
Hasegawa, Aiko; Narimatsu, Shogo; Tanaka, Miyuki; Nagai, Mika; Morita, Daisuke; Saito, Shoji; Nakano, Shigeru; Onozato, Tomoya; Hayashi, Morimichi; Matsuda, Kazuyuki; Yanagisawa, Ryu; Ohnota, Hideki; Nakazawa, Yozo;
MOLECULAR THERAPY, 26(5), 194-195, May 2018, Refereed

Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
Anticancer Research, 38(4), 2227-2234, Apr. 2018, Refereed

Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
Anticancer Research, 38(4), 2227-2234, Apr. 2018, Refereed

Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells
Morita, Daisuke; Nishio, Nobuhiro; Saito, Shoji; Tanaka, Miyuki; Kawashima, Nozomu; Okuno, Yusuke; Suzuki, Satoshi; Matsuda, Kazuyuki; Maeda, Yasuhiro; Wilson, Matthew H.; Dotti, Gianpietro; Rooney, Cliona M.; Takahashi, Yoshiyuki; Nakazawa, Yozo;
MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 8, 131-140, Mar. 2018, Refereed

Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age
Tanaka, Miyuki; Kamata, Takahiro; Yanagisawa, Ryu; Morita, Daisuke; Saito, Shoji; Sakashita, Kazuo; Shiohara, Masaaki; Kurita, Hiroshi; Koike, Kenichi; Nakazawa, Yozo;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 39(3), e150-e154, Apr. 2017, Refereed

Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia
Hirabayashi, Koichi; Takatsuki, Mitsuho; Motobayashi, Mitsuo; Kurata, Takashi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Ishizone, Satoshi; Ota, Hiroyoshi; Koike, Kenichi;
PEDIATRICS AND NEONATOLOGY, 58(1), 81-84, Feb. 2017, Refereed

Catheter-Related Bacteremia Due to Gordonia sputi in a Patient with Acute Lymphocytic Leukemia: a Case Report
Negishi, Tatsuya; Matsumoto, Takehisa; Saito, Shoji; Kasuga, Eriko; Horiuchi, Kazuki; Natori, Tatsuya; Takehara, Kenta; Sugano, Mitsutoshi; Honda, Takayuki;
Japanese journal of infectious diseases, 69(4), 342-343, Jul. 2016, Refereed

Clinical and Laboratory Outcomes After Umbilical Cord Blood Transplantation in a Patient with Mucolipidosis II Alpha/Beta
Shibazaki, Takumi; Hirabayashi, Koichi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Takagi, Mineo; Shiohara, Masaaki; Adachi, Kaori; Nanba, Eiji; Sakai, Norio; Koike, Kenichi;
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 170(5), 1278-1282, May 2016, Refereed

Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction
Hirabayashi, Koichi; Kurata, Takashi; Horiuchi, Kazuki; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
Pediatric blood & cancer, 63(4), 709-711, Apr. 2016, Refereed

Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review
Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Saito, Shoji; Tanaka, Miyuki; Shiohara, Masaaki; Shimodaira, Shigetaka; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 103(1), 107-111, Jan. 2016, Refereed

GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies
Wang, Xinan; Muramatsu, Hideki; Okuno, Yusuke; Sakaguchi, Hirotoshi; Yoshida, Kenichi; Kawashima, Nozomu; Xu, Yinyan; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Saito, Shoji; Nakazawa, Yozo; Masunari, Taro; Hirose, Tadashi; Elmahdi, Shaimaa; Narita, Atsushi; Doisaki, Sayoko; Ismael, Olfat; Makishima, Hideki; Hama, Asahito; Miyano, Satoru; Takahashi, Yoshiyuki; Ogawa, Seishi; Kojima, Seiji;
Haematologica, 100(10), e398-E401, Oct. 2015, Refereed

Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature
Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;
CYTOTHERAPY, 17(3), 330-335, Mar. 2015, Refereed

Successful treatment for West syndrome with severe combined immunodeficiency
Motobayashi, Mitsuo; Inaba, Yuji; Fukuyama, Tetsuhiro; Kurata, Takashi; Niimi, Taemi; Saito, Shoji; Shiba, Naoko; Nishimura, Takafumi; Shigemura, Tomonari; Nakazawa, Yozo; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Ichikawa, Motoki; Koike, Kenichi;
BRAIN & DEVELOPMENT, 37(1), 140-144, Jan. 2015, Refereed

Evaluation of Mucorales DNA load in cerebrospinal fluid in a patient with possible cerebral mucormycosis treated with intravenous liposomal amphotericin B
Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Motobayashi, Mitsuo; Saito, Shoji; Koike, Kenichi;
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 29, 200-202, Dec. 2014, Refereed

Anti-leukemic potency of piggyBac-mediated CD 19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
Saito, Shoji; Nakazawa, Yozo; Sueki, Akane; Matsuda, Kazuyuki; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Sato, Yuko; Okabe, Seiichi; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooney, Cliona M.; Koike, Kenichi;
CYTOTHERAPY, 16(9), 1257-1269, Sep. 2014, Refereed

Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation
Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Sano, Kenji; Yaguchi, Takashi; Motobayashi, Mitsuo; Saito, Shoji; Noda, Shunsuke; Kobayashi, Norimoto; Agematsu, Kazunaga; Honda, Takayuki; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 100(2), 206-209, Aug. 2014, Refereed

Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia
Matsuda, K; Nakazawa, Y; Iwashita, C; Kurata, T; Hirabayashi, K; Saito, S; Tanaka, M; Yoshikawa, K; Yanagisawa, R; Sakashita, K; Sasaki, S; Honda, T; Koike, K
Leukemia, 28(7), 1545-1548, Jul. 2014, Refereed

Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies
Hirabayashi, Kanae; Nakazawa, Yozo; Matsuura, Hiroki; Hara, Yosuke; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 99(4), 477-486, Apr. 2014, Refereed

Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis
Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Kentaro; Hirabayashi, Koichi; Saito, Shoji; Kobayashi, Norimoto; Sakashita, Kazuo; Shiohara, Masaaki; Wada, Taizo; Shimodaira, Shigetaka; Agematsu, Kazunaga; Koike, Kenichi;
TRANSFUSION, 54(3), 516-521, Mar. 2014, Refereed

Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
Hirabayashi, Koichi; Nakazawa, Yozo; Sakashita, Kazuo; Kurata, Takashi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;
SCIENTIFIC REPORTS, 4, 2014, Refereed

Usefulness of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission for Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm With Skin Involvement: A Case Report and Review of Literature
Sakashita, Kazuo; Saito, Shoji; Yanagisawa, Ryu; Tanaka, Miyuki; Yoshikawa, Kentaro; Hirabayashi, Koichi; Tsukahara, Keiko; Motobayashi, Mitsuo; Nakazawa, Yozo; Koike, Kenichi;
Pediatric blood & cancer, 60(11), E140-E142, Nov. 2013, Refereed

Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients
Yanagisawa, Ryu; Shimodaira, Shigetaka; Kojima, Shunsuke; Nakasone, Nobuhiko; Ishikawa, Shinsuke; Momose, Kayo; Honda, Takayuki; Yoshikawa, Kentaro; Saito, Shoji; Tanaka, Miyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Akino, Mitsuaki; Hirayama, Junichi; Azuma, Hiroshi; Koike, Kenichi;
TRANSFUSION, 53(9), 2053-2060, Sep. 2013, Refereed

Recipient seropositivity for adenovirus type 11 (AdV11) is a highly predictive factor for the development of AdV11-induced hemorrhagic cystitis after allogeneic hematopoietic SCT.
23. Nakazawa Y, Saito S, Yanagisawa R, Suzuki T, Ito T, Ishida F, Muramatsu H, Matsumoto K, Kato K, Ishida H, Umeda K, Adachi S, Nakahata T, Koike K.
Bone Marrow Transplant., May;48(5), 737-9, May 2013, Refereed

Food allergy after cord blood transplantation in children
Sakashita, Kazuo; Nakazawa, Yozo; Yanagisawa, Ryu; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Hirabayashi, Koichi; Kusakari, Mai; Kato, Sawako; Hidaka, Nao; Nakayama, Yoshiko; Shigemura, Tomonari; Kobayashi, Norimoto; Kobayashi, Mikiko; Shiohara, Masaaki; Koike, Kenichi;
BRITISH JOURNAL OF HAEMATOLOGY, 158(5), 672-676, Sep. 2012, Refereed

Critical Illness Polyneuropathy and Myopathy Caused by Bacillus Cereus Sepsis in Acute Lymphoblastic Leukemia
Hirabayashi, Koichi; Shiohara, Masaaki; Suzuki, Takefumi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 34(3), E110-E113, Apr. 2012, Refereed

Application of allele-specific quantitative PCR using genomic DNA to monitor minimal residual disease based on mutant gene levels following allogeneic hematopoietic stem cell transplantation in patients with hematological malignancies: Comparison of mutant levels with autologous DNA percentage by short tandem repeat-PCR
Taira, Chiaki; Matsuda, Kazuyuki; Saito, Shoji; Sakashita, Kazuo; Sugano, Mitsutoshi; Okumura, Nobuo; Honda, Takayuki;
CLINICA CHIMICA ACTA, 413(3-4), 516-519, 2012, Refereed

Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
Saito, Shoji; Matsuda, Kazuyuki; Taira, Chiaki; Sano, Kenji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;
LEUKEMIA RESEARCH, 35(12), 1578-1584, Dec. 2011, Refereed

Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome
Hirabayashi, Koichi; Shiohara, Masaaki; Takahashi, Daijiro; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Nakamura, Tomohiko; Ishii, Eizaburo; Koike, Kenichi;
LEUKEMIA & LYMPHOMA, 52(8), 1523-1527, Aug. 2011, Refereed

Disappearance of Minimal Residual Disease After the Early Withdrawal of Immunosuppressants in a Patient With Juvenile Myelomonocytic Leukemia
Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Nakazawa, Yozo; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;
Pediatric blood & cancer, 56(3), 501-502, Mar. 2011, Refereed

Increased pretransplant QT dispersion as a risk factor for the development of cardiac complications during and after preparative conditioning for pediatric allogeneic hematopoietic stem cell transplantation
Motoki, Noriko; Shimizu, Takashi; Akazawa, Yohei; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Motoki, Hirohiko; Nakazawa, Yozo; Sakashita, Kazuo; Iwasaki, Yasushi; Shiohara, Masaaki; Koike, Kenichi;
PEDIATRIC TRANSPLANTATION, 14(8), 986-992, Dec. 2010, Refereed

Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
Matsuda, Kazuyuki; Taira, Chiaki; Sakashita, Kazuo; Saito, Shoji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Fukushima, Keitaro; Oda, Megumi; Honda, Takayuki; Nakahata, Tatsutoshi; Koike, Kenichi;
BLOOD, 115(26), 5429-5431, 2010, Refereed

Polymyxin-Direct Hemoperfusion for Sepsis-Induced Multiple Organ Failure
Hirabayashi, Koichi; Shiohara, Masaaki; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;
Pediatric blood & cancer, 55(1), 202-205, 2010, Refereed

Ela2 Mutations and Clinical Manifestations in Familial Congenital Neutropenia
Shiohara, Masaaki; Shigemura, Tomonari; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Asada, Hiroshi; Ishii, Eizaburo; Koike, Kazutoshi; Chin, Motoaki; Kobayashi, Masao; Koike, Kenichi;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 31(5), 319-324, May 2009, Refereed

Bilateral Perisylvian Polymicrogyria, Periventricular Nodular Heterotopia, and Left Ventricular Noncompaction in a Girl With 10.5-11.1 Mb Terminal Deletion of 1p36
Saito, Shoji; Kawamura, Rie; Kosho, Tomoki; Shimizu, Takashi; Aoyama, Koki; Koike, Kenichi; Wada, Takahito; Matsumoto, Naotnichi; Kato, Mitsuhiro; Wakui, Keiko; Fukushima, Yoshimitsu;
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 146A(22), 2891-2897, 2008, Refereed

CD30+anaplastic large cell lymphoma complicated by pyoderma gangrenosum with increased levels of serum cytokines
Saito, Shoji; Yasui, Kozo; Hosoda, Waki; Ogawa, Mina; Kobayashi, Norimoto; Sakashita, Kazuo; Koike, Kenichi;
EUROPEAN JOURNAL OF HAEMATOLOGY, 77(3), 251-254, Sep. 2006, Refereed

A first-in-human clinical trial of GMR CAR-T for CD116+ myeloid malignancies.
Saito S, Nakazawa Y.
第80回日本癌学会, 01 Oct. 2021

A first-in-human clinical trial of GMR CAR-T for CD116 + myeloid malignancies.
Saito S, Tanaka M, Hasegawa A, Morokawa H, Hirabayashi K, Inada Y, Kojima S, Usami Y, Yanagisawa R, Nakazawa H, Tashiro H, Yagyu S, Nakazawa Y.
第83回日本血液学会学術集会, 24 Sep. 2021

難治性血液腫瘍に対する遺伝子・細胞治療の開発
Shoji Saito
第124回日本小児科学会学術集会, 16 Apr. 2021, Invited

Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
Shoji Saito, Ikumi Nakashima, Aiko Hasegawa, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Shigeki Yagyu, and Yozo Nakazawa
ASGCT 23rd Annual Meeting, 12 May 2020

Mutated GM-CSF-Based CAR T-Cells Targeting CD116/CD131 Complexes Exhibit Enhanced Anti-Tumor Effects Against Acute Myeloid Leukemia
Saito S, Hasegawa A, Nagai M, Inada Y, Morokawa H, Nakashima I, Morita D, Ide Y, Matsuda K, Tashiro H, Yagyu S, Tanaka M, Nakazawa Y
62nd Annual Meeting and Exposition of American Society of Hematology, 2020, Not invited

Tumor-tropic liposome-mediated therapeutic delivery of mRNA for pediatric / adolescent and young adult cancers
Saito S, Nakashima I, Hasegawa A, Akahshi E, Ishihara-Sugano M, Yagyu S, Nakazawa Y
第79回日本癌学会学術集会, 2020, Hiroshima, Japan, Not invited

PiggyBac-modified GM-CSF receptor-specific CAR-T therapy for acute myeloid leukemia.
Saito S, Hasegawa A, Tanaka M, Morita D, Nakashima I, Morokawa H, Nagai M, Inada Y, Matsuda K, Ide Y, Tashiro H, Yagyu S, Tanaka M, Nakazawa Y
82nd Annual meeting of Japanese Society of Hematology, 2020, Kyoto, Japan, Not invited

Combining oncolytic viruses with CAR-T cells for the treatment of solid tumors
齋藤章治
第60回小児血液・がん学会学術集会, 15 Nov. 2018, 小児血液・がん学会

臍帯血移植にて長期寛解を維持しているX連鎖リンパ増殖症 type 2の １例
齋藤章治　中沢洋三　重村倫成　平林耕一　倉田敬　坂下一夫　小池健一　金兼弘和
第55回日本小児血液・がん学会学術集会, 01 Dec. 2013

WT1抗原特異的アロ樹状細胞療法によって長期寛解が得られた難治性急性リンパ性白血病の1例
齋藤章治、田中美幸、柳沢龍、坂下一夫、吉川健太郎、倉田敬、平林耕一、中沢洋三、小池健一、下平滋隆
第75回日本血液学会学術集会20, 11 Oct. 2013, Not invited

CD19-Specific T-Cell Therapy for Refractory Philadelphia-Chromosome-Positive Acute Lymphoblastic Leukemia Using PiggyBac Transposon-Based Gene Modification and Low Autoserum-Containing, but Xeno-Free and Tumor Cell Line-Free Culture System
Saito, Shoji; Nakazawa, Yozo; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooeny, Cliona M.; Koike, Kenichi;
MOLECULAR THERAPY 20 S184-S185, May 2012

Non-Viral Delivery of Therapeutic mRNA Using Tumor-Tropic Liposomes for the Treatment of Solid Tumors
Saito S, Nakashima I, Akahoshi E, Ishihara-Sugano M, Yagyu S, Nakazawa Y.
American Society of Gene and Cell Therapy 24th Annual meeting, Not invited

Jan. 2017
The Internattional Society of Paediatric Oncology (SIOP)

American Society of Gene & Cell Therapy

American Society of Hematology

JAPAN PEDIATRIC SOCIETY

Japanese Society for Transplantation and Cellular Therapy

The Japan Society of Transfusion Medicine and Cell Therapy

Japanse Society of Hematology

The Japanese Society of Pediatric Hematology and Oncology

小児固形がんに対するCAR-T細胞とリポソーム化mRNAワクチンによる複合免疫療法の開発
科学研究費補助金, 基盤研究(C)
01 Apr. 2023 - 31 Mar. 2027

がんに対する新規キメラ抗原受容体(CAR)-T細胞療法開発に関する国際共同研究
国立研究開発法人日本医療研究開発機構
2019 - 2022

固形腫瘍に対する遺伝子改変T細胞と腫瘍溶解ウイルスによる複合免疫療法の開発
科学研究費補助金, 日本学術振興会, 若手研究
01 Apr. 2018 - 31 Mar. 2020

Ph陽性急性リンパ性白血病に対するCD19抗原特異的遺伝子改変T細胞療法の開発
科学研究費補助金, 若手研究（B）
01 Apr. 2012 - 31 Mar. 2013