書籍等出版物 Dendritic Cell-Based Cancer ImmunotherapyTargeting Wilms’ Tumor 1 for Pediatric Cancer Codon Publications 2016(Mar.) Author:Shigetaka Shimodaira, Koichi Hirabayashi, Ryu Yanagisawa,Yumiko Higuchi, Kenji Sano, Tomonobu Koizumi
論文 T cell clonal expansion and STAT3 mutations: a characteristic feature of acquired chronic T cell-mediated pure red cell aplasia INTERNATIONAL JOURNAL OF HEMATOLOGY,115(6):816-825 2022(Jun.) Author:Kawakami, Fumihiro; Kawakami, Toru; Yamane, Taku; Maruyama, Masae; Kobayashi, Jun; Nishina, Sayaka; Sakai, Hitoshi; Higuchi, Yumiko; Hamanaka, Kazutoshi; Hirokawa, Makoto; Nakao, Shinji; Nakazawa, Hideyuki; Ishida, Fumihiro; Keywords:Pure red cell aplasia; STAT3; T cell receptor; Thymoma; Large granular lymphocytic leukemia;
Novel variant fibrinogen gamma p.C352R produced hypodysfibrinogenemia leading to a bleeding episode and failure of infertility treatment INTERNATIONAL JOURNAL OF HEMATOLOGY,114(3):325-333 2021(Sep.) Author:Yoda, Masahiro; Kaido, Takahiro; Kamijo, Tomu; Taira, Chiaki; Higuchi, Yumiko; Arai, Shinpei; Okumura, Nobuo; Keywords:Congenital fibrinogen disorders; Hypodysfibrinogenemia; Fibrinogen gamma chain; Bleeding; Failure of infertility treatment;
Changes in serum citrullinated fibrinogen concentration associated with the phase of bacteremia patients CLINICA CHIMICA ACTA,512:127-134 2021(Jan.) Author:Fujimura, Satoshi; Higuchi, Yumiko; Usami, Yoko; Yamaura, Makoto; Higuchi, Tsukasa; Terasawa, Fumiko; Okumura, Nobuo;
Congenital fibrinogen disorder with a compound heterozygote possessing two novel FGB mutations, one qualitative and the other quantitative THROMBOSIS RESEARCH,196:152-158 2020(Dec.) Author:Yoda, Masahiro; Kaido, Takahiro; Taira, Chiaki; Higuchi, Yumiko; Arai, Shinpei; Okumura, Nobuo;
A Novel Amino Acid Substitution, Fibrinogen B beta p.Pro234Leu, Associated with Hypofibrinogenemia Causing Impairment of Fibrinogen Assembly and Secretion INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,21(24) 2020(Dec.) Author:Kaido, Takahiro; Yoda, Masahiro; Kamijo, Tomu; Arai, Shinpei; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
症例 フィブリノゲン低下の著しい重症線溶亢進型DICに認められた2つのフィブリノゲン遺伝子変異 臨床病理 = The official journal of Japanese Society of Laboratory Medicine : 日本臨床検査医学会誌,68(5):390-397 2020(May) Author:依田 将宏;海藤 貴大;上條 途夢;新井 慎平;平 千明;樋口 由美子;長田 眞;塚田 唯子;奥村 伸生 Keywords:disseminatedintravascularcoagulation:DIC(播種性血管内凝固症候群);fibrinandfibrinogendegradationproducts:FDP(フィブリン・フィブリノゲン分解産物);dysfibrinogenemia(フィブリノゲン機能異常症);hypofibrinogenemia(低フィブリノゲン血症);polymorphism(ポリモルフィズム)
Heterozygous variant fibrinogen gamma A289V (Kanazawa III) was confirmed as hypodysfibrinogenemia by plasma and recombinant fibrinogens INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY,42(2):190-197 2020(Apr.) Author:Kaido, Takahiro; Yoda, Masahiro; Kamijo, Tomu; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
High frequency of STAT3 gene mutations in T-cell receptor (TCR)gamma delta-type T-cell large granular lymphocytic leukaemia: implications for molecular diagnostics BRITISH JOURNAL OF HAEMATOLOGY 2020 Author:Yamane, Taku; Kawakami, Toru; Sekiguchi, Nodoka; Kobayashi, Jun; Ueki, Toshimitsu; Kobayashi, Hikaru; Kawakami, Fumihiro; Nishina, Sayaka; Sakai, Hitoshi; Oshimi, Kazuo; Higuchi, Yumiko; Nakazawa, Hideyuki; Ishida, Fumihiro;
Comparison of molecular structure and fibrin polymerization between two B beta-chain N-terminal region fibrinogen variants, B beta p.G45C and B beta p.R74C INTERNATIONAL JOURNAL OF HEMATOLOGY 2020 Author:Kaido, Takahiro; Yoda, Masahiro; Kamijo, Tomu; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
gamma D318Y fibrinogen shows no fibrin polymerization due to defective "A-a" and "B-b" interactions, whereas that of gamma K321E fibrinogen is nearly normal THROMBOSIS RESEARCH,182:150-158 2019(Oct.) Author:Kamijo, Tomu; Mukai, Saki; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nobuo;
In Vivo Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Increases the Immune Effectiveness of Dendritic Cell-Based Cancer Vaccination VACCINES,7(3) 2019(Sep.) Author:Shimodaira, Shigetaka; Yanagisawa, Ryu; Koya, Terutsugu; Hirabayashi, Koichi; Higuchi, Yumiko; Sakamoto, Takuya; Togi, Misa; Kato, Tomohisa, Jr.; Kobayashi, Takashi; Koizumi, Tomonobu; Koido, Shigeo; Sugiyama, Haruo;
フィブリノゲン蓄積病を呈する異常フィブリノゲン産生細胞の繊維状封入体形成と小胞体ストレス応答 臨床病理 = The official journal of Japanese Society of Laboratory Medicine : 日本臨床検査医学会誌,66(10):1058-1064 2018(Oct.) Author:上條 途夢;大久保 奈緒;平 千明;樋口 由美子;新井 慎平;奥村 伸生 Keywords:hypofibrinogenemia(フィブリノゲン低下症);fibrinogenstoragedisease:FSD(フィブリノゲン蓄積病);intracellularinclusionbodies(細胞内封入体);unfoldedproteinresponses:UPR(小胞体ストレス)
Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors ANTICANCER RESEARCH,38(4):2227-2234 2018(Apr.) Author:Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
Clinical effect and immunological response in patients with advanced malignant glioma treated withWT1-pulsed dendritic cell-based immunotherapy: A report of two cases Interdisciplinary Neurosurgery,9:24-29 2017(Sep.) Author:Sakai, K., Shimodaira, S., Maejima, S., Sano, K., Higuchi, Y., Koya, T., Sugiyama H. & Hongo, K.
WT1 Peptide Vaccine is Unaffected by Airport Screening X-Irradiation Vaccines & Immunother.,3(1) 2016(Sep.) Author:Higuchi Y, Kawakubo M, Yuzawa M, Sano K and Shimodaira S.
Efficacy of dendritic cell-based cancer immunotherapy Biochem Anal Biochem 2016(May) Author:Shigetaka Shimodaira, Yumiko Higuchi, Ryu Yanagisawa, Masato Okamoto, Shigeo Koido.
An update on Dendritic Cell-Based Cancer Immunotherapy Immunome Res,12(1) 2016(Mar.) Author:Shimodaira S, Hirabayashi K, Koya T, Higuchi Y, Yanagisawa R, Okamoto M and Koido S
Future Prospective of Cancer Vaccination Technology in Japan Pharmaceut Reg Affairs,4(2) 2015(Jul.) Author:Shimodaira S, Hirabayashi K, Kobayashi T, Higuchi Y and Yokokawa K
Induction of Antigen-Specific Cytotoxic T Lymphocytes by Chemoradiotherapy in Patients Receiving Wilms’ Tumor 1-Targetted Dendritic Cell Vaccinations for Pancreatic Cancer J Radiol,4(4) 2015(Jul.) Author:Shimodaira S, Kobayashi T, Hirabayashi K, Horiuchi K, Koya T, Mizuno Y, Yamaoka N, Yuzawa M, Ishikawa S, Higuchi Y, Sano K, Ito K, and Koizumi T
Smoking influences the yield of dendritic cells for cancer immunotherapy Pharmaceut Reg Affairs,4(133) 2015(Apr.) Author:Shimodaira S, Higuchi Y, Koya T, Kobayashi T, Yanagisawa R
Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature CYTOTHERAPY,17(3):330-335 2015(Mar.) Author:Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;
Simple polymerase chain reaction for the detection of mutations and deletions in the epidermal growth factor receptor gene: Applications of this method for the diagnosis of non-small-cell lung cancer CLINICA CHIMICA ACTA,401(1-2):68-72 2009(Mar.) Author:Uhara, Miho; Matsuda, Kazuyuki; Taira, Chiaki; Higuchi, Yumiko; Okumura, Nubuo; Yamauchi, Kazuyoshi;
CD20-Negative CD138-Positive Leukemic Large Cell Lymphoma with Plasmablastic Differentiation with an IgH/MYC Translocation in an HIV-Positive Patient INTERNAL MEDICINE,48(7):559-562 2009 Author:Yotsumoto, Mihoko; Ichikawa, Naoaki; Ueno, Mayumi; Higuchi, Yumiko; Asano, Naoko; Kobayashi, Hikaru;
骨髄移植後のキメリズム解析を不可能にした再発時付加染色体異常 臨床血液 = The Japanese Journal of Clinical Hematology,49(2):109-114 2008(Feb. 29) Author:樋口 由美子;伊藤 俊朗;松田 和之;樋口 司;日高 惠以子;今川 英里;宇原 美帆;中澤 英之;石田 文宏;山内 一由;佐野 健司;勝山 努 Keywords:Hematopoietic stem cell transplantation;Chimerism;Fluorescence in situ hybridization;FISH;Short tandem repeats;STR
骨髄移植後のキメリズム解析を不可能にした再発時付加染色体異常 臨床血液 = The Japanese Journal of Clinical Hematology,49(2):109-114 2008(Feb. 29) Author:樋口 由美子; 伊藤 俊朗; 松田 和之; 樋口 司; 日高 惠以子; 今川 英里; 宇原 美帆; 中澤 英之; 石田 文宏; 山内 一由; 佐野 健司; 勝山 努; Keywords:Hematopoietic stem cell transplantation; Chimerism; Fluorescence in situ hybridization; FISH; Short tandem repeats; STR;
CD38 expression by hematopoietic stem cells of newborn and juvenile mice. Leukemia,17(1):171-174 2003(Jan.) Author:Higuchi Y, Zeng H, Ogawa M.
Analysis of hemoglobin and globin chain variants by a commonly used capillary isoelectric focusing method Electrophoresis,21:3016-3019 2000(Sep.) Author:Sugano M, Hidaka H, Yamauchi K, Nakabayahsi T, Higuchi Y, Fujita K, Okumura N, Ushiyama Y, Tozuka M, Katsuyama T.
Thrombopoietin enhances neutrophil production by bone marrow hematopoietic progenitors with the aid of stem cell factor in congenital neutropenia Jounal of Leukocyte Biology.,68(1):137-143 2000(Jul.) Author:Sawai N, Koike K, Mwamtemi HH, Ito S, Kurokawa Y, Sakashita K, Kinoshita T, Higuchi T, Takeuchi K, Shiohara M, Kamijo T, Higuchi Y, Miyazaki H, Kato T,Kobayashi M, Miyake M, Yasui K, Komiyama A.
HPLCを用いたHbA_<1c>の測定により発見された異常ヘモグロビンの解析 医学検査 : 日本臨床衛生検査技師会誌 = The Japanese journal of medical technology,49(6):917-921 2000(Jun. 25) Author:樋口 由美子;関口 香苗;石川 伸介;坪田 芳子;菅野 光俊;戸塚 実;大久保 富美江;奥村 伸生 Keywords:HPLC;HbA_<1c>;異常ヘモグロビン;Hb Hoshida;PCR
HPLCを用いたHbA_<1c>の測定により発見された異常ヘモグロビンの解析 医学検査 : 日本臨床衛生検査技師会誌 = The Japanese journal of medical technology,49(6):917-921 2000(Jun. 25) Author:樋口 由美子; 関口 香苗; 石川 伸介; 坪田 芳子; 菅野 光俊; 戸塚 実; 大久保 富美江; 奥村 伸生; Keywords:HPLC; HbA_<1c>; 異常ヘモグロビン; Hb Hoshida; PCR;
BCR-ABLキメラmRNA検出法の検討 医学検査 : 日本臨床衛生検査技師会誌 = The Japanese journal of medical technology,48(9):1381-1384 1999(Sep. 25) Author:廣田 雅子; 上野 一郎; 石川 雅世; 日高 恵以子; 樋口 由美子; 石川 伸介; 戸塚 実; Keywords:キメラmRNA; RT-nested-PCR; MRD;
Plasminogen Kanagawa-I,a novel missense mutation, is caused by the amino acid substitution G732R British Journal of Haematology,103:867-870 1998(Sep.) Author:Higuchi Y, Furihata K, Ueno I, Ishikawa S, Okumura N, Tozuka M, Sakurai N.
電気抵抗方式を用いた自動血球計数装置における血小板計数異常のスクリーニング法 : 第2報 血液像分析装置を用いた普通塗抹染色標本法の応用 医学検査 : 日本臨床衛生検査技師会誌 = The Japanese journal of medical technology,47(2):133-136 1998(Feb. 25) Author:廣田 雅子; 佐々木 由美子; 石川 伸介; 坪田 芳子; 石川 雅世; 戸塚 実; 山上 修; Keywords:血小板計数; 普通塗抹染色標本法; Fonio 法; 血液像分析装置; 粒度分布図;
Establishment of a GM-CSF-dependent megakaryoblastic cell line with the potential to differentiate into an eosinophilic lineage in response to retinoic acids British Journal of Haematology.,100(2):427-435 1998(Feb.) Author:Ma F, Koike K, Higuchi T, Kinoshita T, Takeuchi K, Mwamtemi HH, Sawai N, Kamijo T, Shiohara M, Horie S, Kawa S, Sasaki Y, Hidaka E, Yamagami O, Yamashita
Megakaryocytes derived from CD34-positive cord blood cells produce interleukin-8 British Journal of Haematology,99:509-516 1997(Dec.) Author:Higuchi T,Koike K,Sawai N,Mwamtemi HH, Takeuchi K,Shiohara M, Kikuchi T, Yasui K, Ito S, Yamagami O, Sasaki Y, Okumura N, Kato T, Miyazaki H, Ikeda M, Yamada M, Komiyama A.
Fibrinogen Matsumoto III: a variant with 275Arg→Cys(CGC→TGC) -comparison of fibrin polymerization with those of Matsumoto I (364Asp→His) and Matsumoto II (308Asn→Lys) Thrombosis and Haemostasis,81(5):763-766 1995(May) Author:Terasawa F, Okumura N, Higuchi Y, Ishikawa S, Tozuka M, Kitano K, Katsuyama T.
多項目自動血球分析装置における白血病細胞検出上の問題点 医学検査 : 日本臨床衛生検査技師会誌 = The Japanese journal of medical technology,44(4):742-746 1995(Apr. 25) Author:中越 りつこ; 石川 伸介; 佐々木 由美子; 奥村 伸生; Keywords:多項目自動血球分析装置; 白血病細胞; 適中度; 検出感度;