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ICHIKAWA Iekuni|Shinshu University Researcher List

ICHIKAWA Iekuni

School of Medicine 

Guest Professor 

Degree

  • 医学, 北里大学

Educational Background

  • 1972, 慶應義塾大学

Award

  • 2007
    Top American Pediatricians
  • 2000
    日本腎臓財団学術賞

Paper

  • Doping Doctors: The Influence of the Marketing Departments of Pharmaceutical Companies on Physician and Researcher Behavior in Japan.
    Ichikawa I, Clayton EW.
    Account Res, 23(4), 245-53, 2016電子ジャーナル
  • Genome-wide association study of IgA nephropathy using 23 465 microsatellite markers in a Japanese population.
    Saka S, Hirawa N, Oka A, Yatsu K, Hirukawa T, Yamamoto R, Matsusaka T, Imai E, Narita I, Endoh M, Ichikawa I, Umemura S, Inoko H.
    J Hum Genet, 60(10), 573-80, Oct. 2015電子ジャーナル
  • Unilateral ureteral obstruction attenuates intrarenal angiotensin II generation induced by podocyte injury.
    Okabe M, Miyazaki Y, Niimura F, Pastan I, Nishiyama A, Yokoo T, Ichikawa I, Matsusaka T.
    Am J Physiol Renal Physiol, 308(8), F932-7, Apr. 2015電子ジャーナル
  • Authorship guidelines and actual practice: are they harmonized in different research systems?
    Vasconcelos S, Vasgird D, Ichikawa I, Plemmons D
    J Microbiol Biol Educ, 15(2), 155-158, Dec. 2014
  • Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury
    Miyazaki Y, Shimizu A, Ichikawa I, Hosoya T, Pastan I, Matsusaka T
    Nephrol Dial Transplant, 29(5), 1005-1012, May 2014
  • Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generation
    Matsusaka T, Niimura F, Pastan I, Shintani A, Nishiyama A, Ichikawa I
    Kidney Int, 85(5), 1068-1077, May 2014
  • Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury
    Hirukawa T, Wu Q, Sawada K, Matsusaka T, Saka S, Oka A, Hirawa N, Umemura S, Kakuta T, Endoh M, Inoko H, Ichikawa I, Fukagawa M
    Nephron Extra, 4(1), 70-81, Apr. 2014
  • Foxc1 gene null mutation causes ectopic budding and kidney hypoplasia but not dysplasia
    Komaki F, Miyazaki Y, Niimura F, Matsusaka T, Ichikawa I, Motojima M
    Cells Tissues Organs, 198(1), 22-27, 2013
  • Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II
    Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I.
    Journal of the American Society of Nephrology, 23(7), 1181-9, 19 Apr. 2012, Refereed
  • Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside.
    Ma J, Matsusaka T, Yang H-C, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I.
    Ped Res, 70, 83-89, 2011
  • Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection.
    Matsusaka T, Kobayashi K, Kon V, Pastan I, Fogo AB, Ichikawa I.
    Am J Physiol Renal Physiol, 300, F792-800, 2011
  • Podocyte injury damages other podocytes. Study of genetically engineered chimeric glomeruli.
    Matsusaka T, Sandgren E, Shintani A, Kon V, Pastan I, Fogo AB, Ichikawa I.
    J Am Soc Nephrol., 22, 1275-1285, 2011
  • Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-Independent.
    Matsusaka T, Asano T, Niimura F, Kinomura M, Shimizu A, Shintani A, Pastan I, Fogo AB, Ichikawa I.
    Hypertension, 55, 967-973, 2010
  • Plasma Macromolecules Activate Toll-like receptor 2 and 4 that May Promote Podocyte Injury.
    Motojima M, Matsusaka T, Ichikawa I.
    Nephron Exp Nephrol, 114, e39-e, 2010
  • Genetic Podocyte Lineage Reveals Progressive Podocytopenia withParietal Cell Hyperplasia in a Murine Model of Cellular/Collapsing Focal Segmental Glomerulosclerosis
    Suzuki T, Matsusaka T, Nakayama M, Asano T, Watanabe T, Ichikawa I, and Nagata M.
    Am. J. Pathol., 174(5), 1675- 1682, 01 May 2009
  • The impact of recent revisions in the Japanese ethical guidelines for clinical research.
    Motojima M, Ichikawa I.
    Asian Bioethics Review 1, 1, 329-341, 2009
  • Megalin participates in the early injury of proximal tubule cells via reabsorption of filtered macromolecules in glomerular disease with non-selective proteinuria.
    Motoyoshi Y, Matsusaka T, Saito A, Pastan I, Willnow TE, Mizutani S, Ichikawa I.
    Kidney Int, 74, 1262-1269, 2008
  • Bmp4 podocytes is essential for normal glomerular capillary formation.
    Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Hosoya T, Ichikawa I.
    J Am Soc Nephrol, 19, 685-694, 2008
  • Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.
    Suganuma E, Babaev VR, Motojima M, Zuo Y, Ayabe N, Fogo AB, Ichikawa I, Linton MF, Fazio S, Kon V.
    J Am Soc Nephrol., 18, 2311-2319, 2007
  • Effects of Podocyte Injury on Glomerular Development.
    Ma J, Rossini M, Yang HC, Zuo Y, Fogo AB, Ichikawa I.
    Ped Res, 62(4), 417-421, 2007
  • Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix expansion.
    Miyazaki Y, Ueda H, Yokoo T, Utsunomiya Y, Kawamura T, Matsusaka T, Ichikawa I, Hosoya T
    Biochem Biophys Res Commun., 340(2), 681-688, 10 Feb. 2006
  • Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice.
    Ayabe N, Babaev VR, Tang Y, Tanizawa T, Fogo AB, Linton MF, Ichikawa I, Fazio S, Kon V
    Atherosclerosis., 184(2), 312-321, Feb. 2006
  • Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.
    Suganuma E, Zuo Y, Ayabe N, Ma J, Babaev VR, Linton MF, Fazio S, Ichikawa I, Fogo AB, Kon V
    J Am Soc Nephrol., 17(2), 433-441, Feb. 2006
  • HIV-1 Genes, vpr and nef, synergistically damage podocytes leading to glomerulosclerosis.
    Zuo Y, Matsusaka T, Zhong J, Ma J, Ma L, Hanna Z, Jolicoeur P, Fogo AB, Ichikawa I.
    J Am Soc Nephrol., 17, 2832-2843, 2006
  • Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy.
    Zhong J, Zuo Y, Ma J, Fogo AB, Jolicoeur P, Ichikawa I, Matsusaka T
    Kidney Int., 68(3), 1048-106, Sep. 2005
  • Permanent genetic tagging of podocytes: fate of injured podocytes in a mouse model of glomerular sclerosis.
    Asano T, Niimura F, Pastan I, Fogo AB, Ichikawa I, Matsusaka T
    J Am Soc Nephrol., 16(8), 2257-2262, Aug. 2005
  • Rapid downregulation of beta-actin-based CAG promoter and filamentous actin in injured podocytes.
    Asano T, Matsusaka T, Mizutani S, Ichikawa I.
    J Med Dent Sci, 52(2), 129-134, 2005
  • Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte-specific injury.
    Matsusaka T, Xin J, Niwa S, Kobayashi K, Akatsuka A, Hashizume H, Wang Q, Pastan I, Fogo AB, Ichikawa I.
    J Am Soc Nephrol, 16, 1013-1023, 2005

Lectures, oral presentations, etc.

  • Toward Global Standardization of Conducting Fair Investigations of Allegations of Research Misconduct
    Iekuni Ichikawa
    4th 2021 Seoul APR, 25 Feb. 2021

Courses

  • 生命倫理・医学概論
    Shinshu University
  • 臨床決断・社会医学
    Shinshu University

Affiliated academic society

  • 日本腎臓学会
  • 日本小児腎臓病学会
  • 日本小児科学会
  • 日本小児保健協会
  • American Society of Nephrology
  • American Federation for Clinical Research
  • American Physiological Society
  • Society for Pediatric Research
  • American Society of Pediatric Nephrology
  • American Society for Clinical Investigation
  • American Association of Physicians

Research Themes

  • 「医生命学系学会の学会員研究倫理素養の均てん化に向けた学修機会の提供」
    日本医療研究開発機構「研究公正高度化モデル開発支援事業」
    01 May 2019 - 31 Mar. 2022
  • glomerulosclerosis