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市川 家國|信州大学 研究者総覧

市川 家國 (イチカワ イエクニ)   

医学部 

客員教授 

学位

  • 医学, 北里大学

学歴

  • 1972年, 慶應義塾大学

受賞

  • 2007年
    Top American Pediatricians
  • 2000年
    日本腎臓財団学術賞

論文

  • Doping Doctors: The Influence of the Marketing Departments of Pharmaceutical Companies on Physician and Researcher Behavior in Japan.
    Ichikawa I, Clayton EW.
    Account Res, 23(4), 245-53, 2016年電子ジャーナル
  • Genome-wide association study of IgA nephropathy using 23 465 microsatellite markers in a Japanese population.
    Saka S, Hirawa N, Oka A, Yatsu K, Hirukawa T, Yamamoto R, Matsusaka T, Imai E, Narita I, Endoh M, Ichikawa I, Umemura S, Inoko H.
    J Hum Genet, 60(10), 573-80, 2015年10月電子ジャーナル
  • Unilateral ureteral obstruction attenuates intrarenal angiotensin II generation induced by podocyte injury.
    Okabe M, Miyazaki Y, Niimura F, Pastan I, Nishiyama A, Yokoo T, Ichikawa I, Matsusaka T.
    Am J Physiol Renal Physiol, 308(8), F932-7, 2015年04月電子ジャーナル
  • Authorship guidelines and actual practice: are they harmonized in different research systems?
    Vasconcelos S, Vasgird D, Ichikawa I, Plemmons D
    J Microbiol Biol Educ, 15(2), 155-158, 2014年12月
  • Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury
    Miyazaki Y, Shimizu A, Ichikawa I, Hosoya T, Pastan I, Matsusaka T
    Nephrol Dial Transplant, 29(5), 1005-1012, 2014年05月
  • Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generation
    Matsusaka T, Niimura F, Pastan I, Shintani A, Nishiyama A, Ichikawa I
    Kidney Int, 85(5), 1068-1077, 2014年05月
  • Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury
    Hirukawa T, Wu Q, Sawada K, Matsusaka T, Saka S, Oka A, Hirawa N, Umemura S, Kakuta T, Endoh M, Inoko H, Ichikawa I, Fukagawa M
    Nephron Extra, 4(1), 70-81, 2014年04月
  • Foxc1 gene null mutation causes ectopic budding and kidney hypoplasia but not dysplasia
    Komaki F, Miyazaki Y, Niimura F, Matsusaka T, Ichikawa I, Motojima M
    Cells Tissues Organs, 198(1), 22-27, 2013年
  • Liver Angiotensinogen Is the Primary Source of Renal Angiotensin II
    Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I.
    Journal of the American Society of Nephrology, 23(7), 1181-9, 2012年04月19日, 査読有り
  • Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside.
    Ma J, Matsusaka T, Yang H-C, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I.
    Ped Res, 70, 83-89, 2011年
  • Glomerular sclerosis is prevented during urinary tract obstruction due to podocyte protection.
    Matsusaka T, Kobayashi K, Kon V, Pastan I, Fogo AB, Ichikawa I.
    Am J Physiol Renal Physiol, 300, F792-800, 2011年
  • Podocyte injury damages other podocytes. Study of genetically engineered chimeric glomeruli.
    Matsusaka T, Sandgren E, Shintani A, Kon V, Pastan I, Fogo AB, Ichikawa I.
    J Am Soc Nephrol., 22, 1275-1285, 2011年
  • Angiotensin receptor blocker protection against podocyte-induced sclerosis is podocyte angiotensin II type 1 receptor-Independent.
    Matsusaka T, Asano T, Niimura F, Kinomura M, Shimizu A, Shintani A, Pastan I, Fogo AB, Ichikawa I.
    Hypertension, 55, 967-973, 2010年
  • Plasma Macromolecules Activate Toll-like receptor 2 and 4 that May Promote Podocyte Injury.
    Motojima M, Matsusaka T, Ichikawa I.
    Nephron Exp Nephrol, 114, e39-e, 2010年
  • Genetic Podocyte Lineage Reveals Progressive Podocytopenia withParietal Cell Hyperplasia in a Murine Model of Cellular/Collapsing Focal Segmental Glomerulosclerosis
    Suzuki T, Matsusaka T, Nakayama M, Asano T, Watanabe T, Ichikawa I, and Nagata M.
    Am. J. Pathol., 174(5), 1675- 1682, 2009年05月01日
  • The impact of recent revisions in the Japanese ethical guidelines for clinical research.
    Motojima M, Ichikawa I.
    Asian Bioethics Review 1, 1, 329-341, 2009年
  • Megalin participates in the early injury of proximal tubule cells via reabsorption of filtered macromolecules in glomerular disease with non-selective proteinuria.
    Motoyoshi Y, Matsusaka T, Saito A, Pastan I, Willnow TE, Mizutani S, Ichikawa I.
    Kidney Int, 74, 1262-1269, 2008年
  • Bmp4 podocytes is essential for normal glomerular capillary formation.
    Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Hosoya T, Ichikawa I.
    J Am Soc Nephrol, 19, 685-694, 2008年
  • Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.
    Suganuma E, Babaev VR, Motojima M, Zuo Y, Ayabe N, Fogo AB, Ichikawa I, Linton MF, Fazio S, Kon V.
    J Am Soc Nephrol., 18, 2311-2319, 2007年
  • Effects of Podocyte Injury on Glomerular Development.
    Ma J, Rossini M, Yang HC, Zuo Y, Fogo AB, Ichikawa I.
    Ped Res, 62(4), 417-421, 2007年
  • Inhibition of endogenous BMP in the glomerulus leads to mesangial matrix expansion.
    Miyazaki Y, Ueda H, Yokoo T, Utsunomiya Y, Kawamura T, Matsusaka T, Ichikawa I, Hosoya T
    Biochem Biophys Res Commun., 340(2), 681-688, 2006年02月10日
  • Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice.
    Ayabe N, Babaev VR, Tang Y, Tanizawa T, Fogo AB, Linton MF, Ichikawa I, Fazio S, Kon V
    Atherosclerosis., 184(2), 312-321, 2006年02月
  • Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.
    Suganuma E, Zuo Y, Ayabe N, Ma J, Babaev VR, Linton MF, Fazio S, Ichikawa I, Fogo AB, Kon V
    J Am Soc Nephrol., 17(2), 433-441, 2006年02月
  • HIV-1 Genes, vpr and nef, synergistically damage podocytes leading to glomerulosclerosis.
    Zuo Y, Matsusaka T, Zhong J, Ma J, Ma L, Hanna Z, Jolicoeur P, Fogo AB, Ichikawa I.
    J Am Soc Nephrol., 17, 2832-2843, 2006年
  • Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy.
    Zhong J, Zuo Y, Ma J, Fogo AB, Jolicoeur P, Ichikawa I, Matsusaka T
    Kidney Int., 68(3), 1048-106, 2005年09月
  • Permanent genetic tagging of podocytes: fate of injured podocytes in a mouse model of glomerular sclerosis.
    Asano T, Niimura F, Pastan I, Fogo AB, Ichikawa I, Matsusaka T
    J Am Soc Nephrol., 16(8), 2257-2262, 2005年08月
  • Rapid downregulation of beta-actin-based CAG promoter and filamentous actin in injured podocytes.
    Asano T, Matsusaka T, Mizutani S, Ichikawa I.
    J Med Dent Sci, 52(2), 129-134, 2005年
  • Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte-specific injury.
    Matsusaka T, Xin J, Niwa S, Kobayashi K, Akatsuka A, Hashizume H, Wang Q, Pastan I, Fogo AB, Ichikawa I.
    J Am Soc Nephrol, 16, 1013-1023, 2005年

講演・口頭発表等

  • Toward Global Standardization of Conducting Fair Investigations of Allegations of Research Misconduct
    市川家國
    4th 2021 Seoul APR, 2021年02月25日
  • 研究倫理(研究不正の現状と対策)および医療安全 ボトムアップの研究倫理教育 CITI Japanプロジェクトの取組
    福嶋義光, 市川家國
    日本内分泌学会雑誌 92 1 136, 2016年04月
  • グローバルな研究者倫理教育を全ての研究者に
    市川家國
    臨床薬理 46 Suppl. S71, 2015年11月

担当経験のある科目_授業

  • 生命倫理・医学概論
    信州大学
  • 臨床決断・社会医学
    信州大学

所属学協会

  • 日本腎臓学会
  • 日本小児腎臓病学会
  • 日本小児科学会
  • 日本小児保健協会
  • American Society of Nephrology
  • American Federation for Clinical Research
  • American Physiological Society
  • Society for Pediatric Research
  • American Society of Pediatric Nephrology
  • American Society for Clinical Investigation
  • American Association of Physicians

共同研究・競争的資金等の研究課題

  • 「医生命学系学会の学会員研究倫理素養の均てん化に向けた学修機会の提供」
    受託事業, 日本医療研究開発機構「研究公正高度化モデル開発支援事業」
    2019年05月01日 - 2022年03月31日
  • 糸球体硬化症の急展開