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ARAI Ryoichi

Academic OrganizationAcademic Assembly School of Science and Technology Institute of Textile Science and TechnologyTEL
Education and Research OrganizationInterdisciplinary Cluster for Cutting Edge Research Institute for Biomedical SciencesFAX
PositionAssociate ProfessorMail Addressrarai[at]shinshu-u.ac.jp
Address3-15-1 Tokida, Ueda, Nagano 386-8567, JAPANWeb sitehttp://fiber.shinshu-u.ac.jp/arai/

Modified:05/29/2019

Profile

Assigned Class
Faculty of Textile Science and Technology Department of Applied Biology
Research Field
Protein engineering, Structural biology, Biotechnology, Synthetic biology
Current Subject
Protein X-ray crystallography

Design and development of artificial proteins

Construction and application of engineered proteins and fusion/chimeric proteins

Academic Societies
Academic Societies
Protein Science Society of Japan
The Society for Biotechnology, Japan
The Molecular Biology Society of Japan
Japanese Society of Enzyme Engineering
Japanese Society for Cell Synthesis Research
Academic Background
Graduate School
The University of Tokyo , (Department of Chemistry and Biotechnology , Graduate School of Engineering) , 2001
The University of Tokyo , (Department of Chemistry and Biotechnology , Graduate School of Engineering) , 1998

College
The University of Tokyo , (School of Engineering) , 1996
Awards
2015 , Encouraging prize of Japanese society of enzyme engineering , "Study on structural analysis of a de novo protein and its application to construction of nanostructures"
2013 , Leave a Nest Grant Direct Detect Award
2011 , PDB40 Travel Award , Protein Data Bank 40th Anniversary Symposium
2011 , Protein Science Young Investigator Travel Grant / The Protein Society Finn Wold Travel Award , IX European Symposium of The Protein Society
2001 , Ishii Science Promotion Award, General Research Promotion Foundation
1996 , Award for graduate student, The Society of Chemical Engineers, Japan
Research Career
Research Career
2016- , Assistant Professor, School of Science and Technology, Academic Assembly, Shinshu University
2016- , Department Head, Department of Supramolecular Complexes, Research Center for Fungal and Microbial Dynamism, Shinshu University
2013- , Visiting Researcher, Division of Structural and Synthetic Biology, Center for Life Science and Technologies, RIKEN
2014-2016 , Assistant Professor, School of Science and Technology, Academic Assembly, Shinshu University
2012-2014 , Assistant Professor, Faculty of Textile Science and Technology, Shinshu University
2007-2012 , Assistant Professor, International Young Researchers Empowerment Center, Shinshu University
2006-2007 , JSPS Postdoctoral Fellow for Research Abroad (Prof. Michael H. Hecht Lab, Princeton University, NJ, USA)
2004-2006 , Research Scientist, Genomic Sciences Center, RIKEN Yokohama Institute (Dr. Shigeyuki Yokoyama Gr.)
2001-2004 , Research Associate, Genomic Sciences Center, RIKEN Yokohama Institute (Dr. Shigeyuki Yokoyama Gr.)
1998-2001 , JSPS Research Fellow (DC1)

Overseas Education
2006-2007 , Research fellow, Department of Chemistry, Princeton University, NJ, USA (Prof. Michael H. Hecht Lab.)

Research

Books, Articles, etc.
Books
Characterization of underwater silk proteins from caddisfly larva, Stenopsyche marmorata
Springer, New York , Biotechnology of Silk: Biologically inspired systems Volume 5 , :Ch. 6, pp. 107-122 2013
Author:Ohkawa, K., Nomura, T., Arai, R., Hirabayashi, K., Tsukada, M., and Abe , K.


Articles
Design of hollow protein nanoparticles with modifiable interior and exterior surfaces
Angewandte Chemie International Edition,:in press 2018
Author:Norifumi Kawakami, Hiroki Kondo, Yuki Matsuzawa, Kaoru Hayasaka, Erika Nasu, Kenji Sasahara, Ryoichi Arai, Kenji Miyamoto


Self-assembling supramolecular nanostructures constructed from de novo extender protein nanobuilding blocks
ACS Synthetic Biology,7(5):1381-1394 2018
Author:Naoya Kobayashi, Kouichi Inano, Kenji Sasahara, Takaaki Sato, Keisuke Miyazawa, Takeshi Fukuma, Michael H Hecht, Chihong Song, Kazuyoshi Murata, and Ryoichi Arai


Hierarchical design of artificial proteins and complexes toward synthetic structural biology
Biophysical Reviews,10:391-410 2018
Author:Arai, R.


Comparative analysis of plant isochorismate synthases reveals structural mechanisms underlying their distinct biochemical properties
Bioscience Reports,38:BSR20171457 2018
Author:2. Yokoo, S., Inoue, S., Suzuki, N., Amakawa, N., Matsui, H., Nakagami, H., Takahashi, A., Arai R. and Katou, S.


Design and construction of self-assembling supramolecular protein complexes using artificial and fusion proteins as nanoscale building blocks
Current Opinion in Biotechnology,46:57–65 2017
Author:Kobayashi, N. and Arai, R.


Flight density of the aquatic insect fauna over the water surface in the middle reaches of the Shinano River, Japan, mainly among caddisflies (Trichoptera)
Zoosymposia,10:203–213 2016
Author:Hirabayashi, K.*, Ikutama, E., Ohkawa, K., Arai, R., Nomura, T., Tsukada, M., and Abe, K.


Characterization of silk gland ribosomes from a bivoltine caddisfly, Stenopsyche marmorata: translational suppression of a silk protein in cold conditions.
Biochemical and Biophysical Research Communications,469:210-215 2016
Author:Takaomi Nomura, Miho Ito, Mai Kanamori, Yuta Shigeno, Toshio Uchiumi, Ryoichi Arai, Masuhiro Tsukada, Kimio Hirabayashi, Kousaku Ohkawa


Expression, purification, crystallization and X-ray diffraction analysis of ChiL, a chitinase from Chitiniphilus shinanonensis
Acta Cryst. F,F71(12):1516–1520 2015(Dec.)
Author:Miruku Ueda, Makoto Shimosaka and Ryoichi Arai


Molecular cloning, gene expression analysis, and recombinant protein expression of novel silk proteins from larvae of a retreat-maker caddisfly, Stenopsyche marmorata
Biochem. Biophys. Res. Commun.,464(3):814–819 2015
Author:Xue Bai, Mayo Sakaguchi, Yuko Yamaguchi, Shiori Ishihara, Masuhiro Tsukada, Kimio Hirabayashi, Kousaku Ohkawa, Takaomi Nomura, Ryoichi Arai


Self-Assembling Nano-Architectures Created from a Protein Nano-Building Block Using an Intermolecularly Folded Dimeric De Novo Protein
J. Am. Chem. Soc.,137(35):11285–11293 2015
Author:Naoya Kobayashi, Keiichi Yanase, Takaaki Sato, Satoru Unzai, Michael H. Hecht, Ryoichi Arai


Crystal structure of ChiL, a chitinase from Chitiniphilus shinanonensis
Photon Factory Activity Report 2014,32(B):206 2015
Author:Ueda, M., Shimosaka, M., and Arai, R.


Crystal structure of Fab fragment of an anti-Osteocalcin C-Terminal peptide antibody KTM219
Photon Factory Activity Report 2014,32(B):205 2015
Author:Komatsu, M., Dong, J., Ueda, H., and Arai, R.


Crystal structure of glycine oxidase from Geobacillus kaustophilus
Photon Factory Activity Report 2014,32(B):204 2015
Author:Shiono, T., Nomura, T., Nishiya, Y., and Arai, R.


Intermolecular interactions and molecular dynamics in bovine serum albumin solutions studied by small angle X-ray scattering and dielectric relaxation spectroscopy.
J. Mol. Liq.,200(A):59-66 2014
Author:Yanase, K., Arai R., and Sato, T.


Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.
Hum. Mol. Genet.,23:6495-6511 2014
Author:Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada, Y, Kobayashi T, and Yoshikawa T


Crystal structure of glycine oxidase from Bacillus thuringiensis
Photon Factory Activity Report 2013,31(B):274 2014
Author:Ohishi, S., Shiono, T., Nishiya, Y., Nomura, T., and Arai, R.


バイナリーパターンデザインによるデノボタンパク質WA20のドメインスワップ二量体構造
酵素工学研究会誌,69:19-25 2013
Author:小林直也,*新井亮一


Chain conformational study on underwater silk protein from caddisfly, Stenopsyche marmorata: Implication of a fiber-forming mechanism
Adv. Mater. Res.,796:41706 2013
Author:Ohkawa, K., Hachisu, M., Nomura, T., Arai, R., Hirabayashi, K., Tsukada, M., and Abe, K


Long-range periodic sequence of Stenopsyche marmorata cement/silk protein: Purification and biochemical characterization
Biofouling,29(4):357-367 2013
Author:Ohkawa, K., Miura, Y., Nomura, T., Arai, R., Abe, K., Tsukada M. and Hirabayashi, K.


Isolation of silk proteins from a caddisfly larva, Stenopsyche marmorata.
J. Fiber Bioeng. Informatics,5:125-137 2012
Author:Ohkawa, K., Miura, Y., Nomura, T., Arai, R., Abe, K., Tsukada M. and Hirabayashi, K.


Solution structure of IseA, an inhibitor protein of DL-endopeptidases from Bacillus subtilis, reveals a novel fold with a characteristic inhibitory loop
J. Biol. Chem.,287(53):44736-44748 2012
Author:Arai, R., Fukui, S., Kobayashi, N. and Sekiguchi, J.


Domain-Swapped Dimeric Structure of a Stable and Functional De Novo 4-Helix Bundle Protein, WA20
J. Phys. Chem. B,116(23):6789-6797 2012
Author:Arai, R., Kobayashi, N., Kimura, A., Sato, T., Matsuo, K., Wang, A.F., Platt, J.M., Bradley, L.H., Hecht, M.H.


Crystal structure of a menaquinone biosynthetic enzyme, TthMqnD, complexed with its product, 1,4-dihydroxy-6-naphthoate
Photon Factory Activity Report 2010,28:B298 2011
Author:Matsuo, K., Dairi, T., Seto, H. and Arai, R.


Crystal structure of a dimeric de novo 4-helix bundle protein, WA20
Photon Factory Activity Report 2010,28:B256 2011
Author:Arai, R., Kobayashi, N., Kimura, A., Sato, T., Wang, A.F., Platt, J.M., Bradley, L.H. and Hecht, M.H.


Dissecting cell signaling pathways with genetically encoded 3-iodo-L-tyrosine
ChemBioChem,12:387-389 2011
Author:Hayashi A, Hino N, Kobayashi T, Arai R, Shirouzu M, Yokoyama S, Sakamoto K.


Polymorphism screening of brain-expressed FABP7, 5 and 3 genes and association studies in autism and schizophrenia in Japanese subjects
J. Hum. Genet.,55:127-130 2010
Author:Maekawa, M.,Iwayama, Y., Arai, R., Nakamura, K., Ohnishi, T., Toyota, T., Tsujii, M., Okazaki, Y., Osumi, N., Owada, Y., Mori, N., and Yoshikawa, T.


Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8
J. Struct. Biol,168:575-581 2009
Author:Arai, R., Murayama, K., Uchikubo-Kamo, T., Nishimoto, M., Toyama, M., Kuramitsu, S., Terada, T., Shirouzu, M. and Yokoyama, S.


Fabp7 Maps to a Quantitative Trait Locus for a Schizophrenia Endophenotype
PLoS Biol.,5:e297 2007
Author:Watanabe, A., Toyota, T., Owada, Y., Hayashi, T., Iwayama, Y., Matsumata, M., Ishitsuka, Y., Nakaya, A., Maekawa, M., Ohnishi, T., Arai, R., Sakurai, K., Yamada, K., Kondo, H., Hashimoto, K., Osumi, N. and Yoshikawa T.


Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures
Proteins,67:732-742 2007
Author:Arai, R.,* Ito, K.,* Ohnishi, T., Ohba, H., Akasaka, R., Bessho, Y., Hanawa-Suetsugu, K., Yoshikawa, T., Shirouzu, M. and Yokoyama, S.


Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate
Acta Crystallogr. D,63:357-365 2007
Author:Yoshikawa, S.,* Arai, R.,* Kinoshita, Y., Uchikubo-Kamo, T., Wakamatsu, T., Akasaka, R., Masui, R., Terada, T., Kuramitsu, S., Shirouzu, M. and Yokoyama, S. (*The authors contributed equally to the work.)


Crystal structure of the conserved protein TTHA0727 from Thermus thermophilus HB8 at 1.9 A resolution: A CMD family member distinct from carboxymuconolactone decarboxylase (CMD) and AhpD
Protein Sci.,15:1187-1192 2006
Author:Ito, K.,* Arai, R.,* Fusatomi, E., Kamo-Uchikubo, T., Kawaguchi, S., Akasaka, R., Terada, T., Kuramitsu, S., Shirouzu, M. and Yokoyama, S.


Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)
Acta Crystallogr. F,62:330-334 2006
Author:Arai, R.,* Yoshikawa, S.,* Murayama, K., Imai, Y., Takahashi, R., Shirouzu, M. and Yokoyama, S.


Crystal structure of the probable haloacid dehalogenase PH0459 from Pyrococcus horikoshii OT3
Protein Sci.,15:373-377 2006
Author:Arai, R., Kukimoto-Niino, M., Kuroishi, C., Bessho, Y., Shirouzu, M. and Yokoyama, S.


Crystal structure of an enhancerof rudimentary homolog (ERH) at 2.1 Angstroms resolution
Protein Sci.,14:1888-1893 2005
Author:Arai, R., Kukimoto-Niino, M., Uda-Tochio, H., Morita, S., Uchikubo-Kamo, T., Akasaka, R., Etou, Y., Hayashizaki, Y., Kigawa, T., Terada, T., Shirouzu, M. and Yokoyama, S.


Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase
Biochim. Biophys. Acta,1750:40-47 2005
Author:Arai, R.,* Nishimoto, M.,* Toyama, M., Terada, T., Kuramitsu, S., Shirouzu, M. and Yokoyama, S. Conserved protein TTHA1554 from Thermus thermophilus HB8 binds to glutamine synthetase and cystathionine beta-lyase


Establishment of stable hFis1 knockdown cells with an siRNA expression vector
J. Biochem.,136:421-425 2004
Author:Arai, R.,* Ito,K.,* Wakiyama, M., Matsumoto, E., Sakamoto, A., Etou, Y., Otsuki, M., Inoue, M., Hayashizaki, Y., Miyagishi, M., Taira, K., Shirouzu, M. and Yokoyama, S.


Phosphorylation analysis of 90 kDa heat shock protein within the cytosolic arylhydrocarbon receptor complex
Biochemistry,43:15510-15519 2004
Author:Ogiso, H., Kagi, N., Matsumoto, E., Nishimoto, M., Arai, R., Shirouzu, M., Mimura, J., Fujii-Kuriyama, Y. and Yokoyama, S.


Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering
Proteins,57:829-838 2004
Author:Arai, R., Wriggers, W., Nishikawa, Y., Nagamune, T. and Fujisawa, T.


An optimized homogeneous noncompetitive immunoassay based on the antigen-driven enzymatic complementation
J. Immunol. Methods,279:209-218 2003
Author:Ueda, H., Yokozeki, T., Arai, R., Tsumoto, K., Kumagai, I. and Nagamune, T.


A homogeneous noncompetitive immunoassay for the detection of small haptens
Anal. Chem.,74:2500-2504 2002
Author:Yokozeki, T., Ueda, H., Arai, R., Mahoney, W. and Nagamune, T.


A homogeneous and noncompetitive immunoassay based on the enhanced fluorescence resonance energy transfer by leucine zipper interaction
Anal. Chem.,74:5786-5792 2002
Author:Ohiro, Y., Arai, R., Ueda, H. and Nagamune, T.


Detection of protein-protein interaction by bioluminescence resonance energy transfer from firefly luciferase to red fluorescent protein
J. Biosci. Bioeng.,94:362-364 2002
Author:Arai, R., Nakagawa, H., Kitayama, A., Ueda, H. and Nagamune, T


Demonstration of a homogeneous noncompetitive immunoassay based on bioluminescence resonance energy transfer
Anal. Biochem.,289:77-81 2001
Author:Arai, R., Nakagawa, H., Tsumoto, K., Mahoney, W., Kumagai, I., Ueda, H. and Nagamune, T.


Design of the linkers which effectively separate domains of a bifunctional fusion protein
Protein Eng.,14:529-532 2001
Author:Arai, R., Ueda, H., Kitayama, A., Kamiya, N. and Nagamune, T.


Construction of green fluorescent protein reporter genes for genotoxicity test (SOS/umu-Test) and improvement of mutagen-sensitivity
J. Biosci. Bioeng,92:301-304 2001
Author:Arai, R., Makita, Y., Oda, Y. and Nagamune, T.


Design of an artificial light-harvesting unit by protein engineering: Cytochrome b(562)-green fluorescent protein chimera
Biochem. Biophys. Res. Commun.,289:299-304 2001
Author:Takeda, S., Kamiya, N., Arai, R. and Nagamune, T.


Fluorolabeling of antibody variable domains with green fluorescent protein variants: application to an energy transfer-based homogeneous immunoassay
Protein Eng.,13:369-376 2000
Author:Arai, R., Ueda, H., Tsumoto, K., Mahoney, W.C., Kumagai, I. and Nagamune, T.


Construction of chimeric proteins between protein G and fluorescence-enhanced green fluorescent protein, and their application to immunoassays
J. Ferment. Bioeng.,86:440-445 1998
Author:Arai, R., Ueda, H. and Nagamune, T.


Presentations
Molecular cloning of novel silk proteins from larvae of caddisfly, Stenopsyche marmorata
8th Chaina International Silk Conference 2013 , :ISC1-001 2013
Author:K. Ohkawa, M. Hachisu, T.Nomura, R.Arai, K. Hirabayashi, M. Tsukada and K. Abe


Molecular cloning of novel silk proteins from larvae of caddisfly, Stenopsyche marmorata
Young Researcher Symposium 2013 , :117-118 2013
Author:X.Bai, K.Ohkawa, T.Nomura, S.Ishihara, Y.Yamaguchi, M.Tsukada, K.Abe, K.Hirabayashi, R. Arai


Construction and characterization of tandem WA20 domain-swapped de novo proteins with various linkers.
27th Annual Symposium of The Protein Society. 2013
Author:Naoya Kobayashi, N., Michael H. Hecht, and Ryoichi Arai


Biochemical natures of underwater silk proteins from caddisfly, Stenopsyche marmorata
The international Textile Conference 2013 , :p. 90 2013
Author:Kousaku Ohkawa, Masakazu Hachisu, Takaomi Nomura, Ryoichi Arai, Masuhiro Tsukada and Kimio Hirabayashi


Characterization and Nanofiber Fabrication of Underwater Silk Protein from Stenopsyche marmorata
American Chemical Society, National Meething, 2013 Spring , :Paper ID 18339 2013
Author:Kousaku Ohkawa, Yumi Miura, Takaomi Nomura, Ryoichi Arai, Kimio Hirabayashi, Masuhiro Tsukada, and Koji Abe


Structural and functional analyses of binary pattern designed de novo proteins
Enzyme Engineering XXII 2013
Author:Arai, R. Kobayashi, N., Fukuda, S., Kurasawa, S. and Hecht, M. H.


Solution structure of IseA, an inhibitor protein of DL-endopeptidases from Bacillus subtilis, reveals a novel fold with a characteristic inhibitory loop
International Conference on Structural Genomics 2013 (ICSG2013) 2013
Author:Arai, R., Fukui, S., Kobayashi, N. and Sekiguchi, J.


A De Novo Heme Protein, Dnhps1, Created from a 5-Amino Acid Alphabet
27th Annual Symposium of The Protein Society 2013
Author:Fukuda, S., Kurasawa, S., and Arai, R.


Crystal structures of MqnD, a menaquinone biosynthetic enzyme, complexed with the product, 1,4-dihydroxy-6-naphthoate, and its analogs
4th International Symposium on Diffraction Structural Biology 2013 (ISDSB2013) 2013
Author:Arai, R., Matsuo, K. and Dairi, T.


Isolation of silk proteins from a caddisfly larva, Stenopsyche marmorata
Textile Bioengneering Informatics Symposium 2012 , :233–242 2012
Author:Kousaku Ohkawa, Yumi Miura, Takaomi Nomura, Ryoichi Arai, Koji Abe, Masuhiro Tsukada and Kimio Hirabayashi


Underwater silk fibers–Biochemical natures for novel textile technology
9th Asia-Pacific Marine Biotechnogy Conference , :P-059 2012
Author:Kousaku Ohkawa, Yumi Miura, Takaomi Nomura, Ryoichi Arai, Koji Abe, Masuhiro Tsukada and Kimio Hirabayashi


Domain-Swapped Dimeric Structure of a Stable and Functional De Novo Four-Helix Bundle Protein WA20, and its Potential Application
18th Symposium of Young Asian Biochemical Engineers' Community (YABEC2012) , :PC-8 2012
Author:Arai, R., Kobayashi, N., Kimura, A., Sato, T., and Hecht, M. H.


De novo proteins and interaction analysis using pattern-designed peptide libraries
Gordon Research Conference, Intrinsically Disordered Proteins 2012
Author:Arai, R., Kobayashi, N., Kimura, A., Teranishi, H., Sato, T., Bradley, L. H., Nishimura, Y., and Hecht, M. H.


Flight density of aquatic insects fauna over river water surface in the middle reaches of the Shinano River, Japan, with emphasis on Trichoptera.
14th International symposium on Trichoptera 2012
Author:Hirabayashi K., Ohkawa K., Arai R., Nomura T., Tsukada M. and Abe K.


Function and Three Dimensional Structure of an Autolysin Inhibitor IseA from Bacillus subtilis
American Society for Microbiology, General Meeting (asm2012) 2012
Author:Junichi Sekiguchi and Ryoichi Arai


Repetitive Sequential Motifs of Underwater Silk Protein from Caddisfly, Stenopsyche marmorata, 
American Chemical Society, Annual Meeting Spring 2012 , :BIOL163 2012
Author:Kousaku OHKAWA, Yumi MIURA, Takaomi NOMURA, Ryoichi ARAI, Kimio HIRABAYASHI, Masuhiro TSUKADA, and Koji ABE


Domain-swapped dimeric structure of a stable and functional de novo 4-helix bundle protein, WA20
6th International Conference on Advanced Fiber/Textile Materials 2011 , :IP-12, p.18 2011
Author:Kobayashi, N., Kimura, A., Sato, T., Matsuo T., Wang, A. F., Platt, J., Bradley, L. H. Hecht, M. H. and Arai, R.,


Domain-swapped dimeric structure of a de novo 4-helix bundle protein, WA20
PDB40 Symposium (A Special Symposium Celebrating the 40th Anniversary of the Protein Data Bank) , :2 2011
Author:Arai, R., Kobayashi, N., Kimura, A., Sato, T., Wang, A. F., Platt, J., Bradley, L. H. and Hecht, M. H.


Crystal structure of a dimeric de novo 4-helix bundle protein WA20
IX European Symposium of The Protein Society , :13013, p.87 2011
Author:Arai, R., Kimura, A., Kobayashi, N., Sato, T., Wang, A. F., Platt, J., Bradley, L. H. and Hecht, M. H.


Crystal structure of MqnD, a menaquinone biosynthetic enzyme from Thermus thermophilus HB8
Gordon Research Conference, Biopolymers , :0 2010
Author:Arai, R., Murayama, K., Uchikubo-kamo, T., Nishimoto, M., Toyama, M., Kuramitsu, S., Terada, T., Shirouzu, M. and Yokoyama, S.


Protein Composition in Silk Grand of Caddisfly, Stenopsyche Marmorata, Larva.
14th International Symposium on River and Lake Environments , :Global-COE session: Biofiber of aquatic insects 2009
Author:K. Ohkawa, T. Nomura, R.Arai, K. Abe, M. Tsukada, K. Hirabayashi


A four-helix bundle de novo heme protein by phage display screening
7th East Asian Symposium on Polymers for Advanced Technologies (EASPAT 2009) , :PS04, p.68 2009
Author:R. Arai, M. H. Hecht


Crystal structure of MqnD (TTHA1568), a menaquinone biosynthetic enzyme from Thermus thermophilus HB8
21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology , :B-6-018, p.105 2009
Author:R. Arai, K. Murayama, T. Uchikubo-Kamo, M. Nishimoto, M. Toyama, S. Kuramitsu, T. Terada, M. Shirouzu, S. Yokoyama


Design and construction of functional artificial proteins: Phage display screening of four-helix bundle de novo proteins
4th International Conference on Advanced Fiber/Textile Materials 2007 in Ueda (ICAFTM2007) , :PA-18, p.73 2007
Author:R. Arai, M.H. Hecht

Education

Lectures
2013 , Seminar in Scientific Presentation Writing and Presentation
2013 , Practical Exercises of Field Science
2013 , Freshman Seminar
2013 , Experiments in Basic Chemistry
2013 , Biochemistry II
2013 , Experiments in Bioresource Application
2013
2012 , Seminar in Scientific Presentation Writing and Presentation
2012 , Practical Exercises of Field Science
2012 , Freshman Seminar
2012 , Biochemistry II
2012 , Experiments in Bioresource Application
2011 , Seminar in Scientific Presentation Writing and Presentation
2011 , Practical Exercises of Field Science
2011 , Biochemistry II
2011 , Experiments in Bioresource Application
2010 , Seminar in Scientific Presentation Writing and Presentation
2010 , Practical Exercises of Field Science
2010 , Biochemistry II
2010 , Experiments in Bioresource Application
2009 , Experiments in Molecular Bioengineering
2009 , Biochemistry II
2008 , Molecular Biology II
2008 , Experiments in Molecular Bioengineering
Thesis Guidance
2013
Graduation Thesis Number of Students Total:3
Master's Thesis Number of Students Total:2
Doctor's Thesis Number of Students Total:1

2012
Graduation Thesis Number of Students Total:2
Master's Thesis Number of Students Total:4
Researcher's Thesis Number of Students Total:1

2011
Graduation Thesis Number of Students Total:2(International Students:1)
Master's Thesis Number of Students Total:4

2010
Graduation Thesis Number of Students Total:2
Master's Thesis Number of Students Total:2

2009
Graduation Thesis Number of Students Total:2

2008
Graduation Thesis Number of Students Total:1

International Student Receipt
2013 , First Term:1 , Second Term:1 , M2
2012 , First Term:1 , Second Term:1 , M1
2011 , First Term:1 , Second Term:1 , B4