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AKIYAMA Yoshitake

Academic OrganizationAcademic Assembly School of Science and Technology Institute of Textile Science and TechnologyTEL+81-268-21-5517
Education and Research OrganizationFaculty of Textile Science and Technology Department of Mechanical Engineering and Robotics Course of BioengineeringFAX
PositionAssociate ProfessorMail
Address3-15-1, Tokida, Ueda City 386-8567Web site


Research Field
Intelligent mechanics/Mechanical systems
Nano/Micro Systems
Biomedical Engineering
Academic Societies
Academic Societies
The Society for Biotechnology, Japan (SBJ)
The Japan Society of Mechanical Engineers (JSME)
The Japanese Society for Regenerative Medicine (JSRM)
The Society for Chemistry and Micro-Nano Systems (CHEMINAS)
Academic Background
Graduate School

2017 , ROBOMECH Award
2016 , SI2016 Best Presentation Award
2015 , SI2015 Best Presentation Award
2014 , SI2014 Best Presentation Award
2012 , Inoue Research Award for Young Scientists
2011 , Takagi Award
2010 , Outstanding Paper Award for Young C&C Researchers
2009 , Best Conference Paper Award
2009 , Best Paper Award
2007 , Young Investigation Excellence Award
2007 , The Award for the Best Article presented in the 29th Annual Meeting of the Japanese Society for Comparative Physiology and Biochemistry
Research Career
Research Career

Other Career


Books, Articles, etc.
Design considerations for muscle-actuated biohybrid devices
Wiley-VCH Verlag GmbH & Co. KGaA , Nanotechnology and Microfluidics, First Edition , :347-381 2019( ??)
Author:Y. Akiyama, S-J. Park, S. Takayama

第6章 相対的反磁性アセンブリを使った微小構造体上への筋組織構築
シーエムシー・リサーチ , 骨格筋研究を核とした筋スマート社会 , :159-163 2019(Jun. 14)

Rapid Single Cell Printing by Piezoelectric Inkjet Printer
Springer , Engineered Cell Manipulation for Biomedical Application 2014
Author:R. The, S. Yamaguchi, A. Ueno, Y. Akiyama, K. Morishima

第11節 筋細胞ビルドアップ型バイオアクチュエータの開発
NTS出版 , アクチュエータ研究開発の最前線 , :231-238 2011(Aug. 08)

低温生物工学会誌,66(1) 2020( ??)

化学とマイクロ・ナノシステム学会誌,18(2):29-32 2019(Oct. 01)

Nylon mesh cryodevice for bovine mature oocytes, easily removable excess vitrification solution
Cryobiology,90:96-99 2019(Sep. 21)
Author:S. Chinen, T. Yamanaka, K. Nakayama, H. Watanabe, Y. Akiyama, M. Hirabayashi, S. Hochi

Insect Muscular Tissue-Powered Swimming Robot
Actuators 2019(Apr. 08)
Author:Y. Yalikun, K. Uesugi, M. Hiroki, Y. Shen, Y. Tanaka, Y. Akiyama, K. Morishima

Cryoprotectant-free cryopreservation of mammalian cells by superflash freezing
Proceedings of the National Academy of Sciences of the United States of America,116(16):7738-7743 2019(Apr. 01)
Author:Yoshitake Akiyama, Masato Shinose, Hiroki Watanabe, Shigeru Yamada, and Yasunari Kanda

Temperature-responsive culture surfaces for insect cell sheets to fabricate a bioactuator
Advanced Robotics 2019(Jan. 25)
Author:Kaoru Uesugi, Yui Sakuma, Yoshitake Akiyama, Yoshikatsu Akiyama, Kikuo Iwabuchi, Teruo Okano, Keisuke Morishima

細胞,50(9):484-487 2018(Jul. 21)

ケミカルエンジニヤリング,62(9):35-41 2017

Contractile Performance and Controllability of Insect Muscle-Powered Bioactuator with Different Stimulation Strategies for Soft Robotics
Soft Robotics,3(1):13-22 2016
Author:K. Uesugi, K. Shimizu, Y. Akiyama, T. Hoshino, K. Iwabuchi, K. Morishima

Biofuel cell backpacked insect and its application to wireless sensing
Biosensors and Bioelectronics,78(15):390-395 2016
Author:K. Shoji, Y. Akiyama, M. Suzuki, N. Nakamura, H. Ohno, K. Morishima

Insect biofuel cell using an electrode with gold nanoparticles deposited by sputtering
Micro & Nano Letters,10(12):674-677 2015
Author:Kan Shoji, Yoshitake Akiyama, Masato Suzuki, Nobuhumi Nakamura, Hiroyuki Ohno, Keisuke Morishima

Toward Continuous LC-MS Analysis: Surface Modification of Magnetic Microparticles with TiO2 for Phosphate Adsorption
Bioscience, Biotechnology, and Biochemistry,78(5):748-754 2014
Author:I. Akutagawa, Y. Akiyama, Y. Takahashi, M. Iijima, Y. Okada, H. Kamiya, K. Chiba

Voluntary Movement Controlled by the Surface EMG Signal for Tissue-engineered Skeletal Muscle on a Gripping Tool
Tissue Engineering A,19(15-16):1695-1703 2013
Author:K. Kabumoto, T. Hoshino, Y. Akiyama, K. Morishima

Measuring mechanical properties of cell sheet by tensile test using self-attachable fixture
Journal of Robotics and Mechatronics,25(4):603-610 2013
Author:K. Uesugi, Y. Akiyama, T. Hoshino, Y. Akiyama, M. Yamato, T. Okano, K. Morishima

Bio-Manipulation Method Based on Hydrodynamic Forces of Multiple Microfluidic Streams
Journal of Robotics and Mechatronics,25(4):611-618 2013
Author:Y.Yalikun, Y. Akiyama, T. Hoshino, K. Morishima

Measuring Adhesion Force of a Cell Sheet by the Ninety-degree Peel Test Using a Multi Hook Type Fixture
Journal of Biomechanical Science and Engineering,8(2):129-138 2013
Author:K. Uesugi, Y. Akiyama, T. Hoshino, Y. Akiyama, M. Yamato, T. Okano, K. Morishima

Atmospheric-operable bioactuator powered by insect muscle packaged with medium.
Lab on a Chip,12(24):4870-4880 2013
Author:Y. Akiyama, K. Funakoshi, T. Hoshino, K. Iwabuchi, K. Morishima

Evaluation of mechanical stimulation effect on cellular orientation under confluence based on 2D-FFT and principal component analysis
Journal of Micro-Nano Mechatronics,7(1-3):69-77 2012(Dec.)
Author:Y. Akiyama, T. Hoshino, M. Hashimoto, K. Morishima

Cell patterning through inkjet printing of one cell per droplet
Biofabrication,4:045005 2012(Oct. 17)
Author:S. Yamaguchi, A. Ueno, Y. Akiyama, K. Morishima

Rapidly-moving insect muscle-powered microrobot and its chemical acceleration
Biomedical Microdevices,14(6):979-986 2012(Sep.)
Author:Y. Akiyama, K. Odaira, K. Sakiyama, T. Hoshino, K. Iwabuchi, K. Morishima

Room temperature operable autonomously moving bio-microrobot powered by insect dorsal vessel tissue
PoLS ONE,7(7):e38274 2012(Jul.)
Author:Y. Akiyama, T. Hoshino, K. Iwabuchi, K. Morishima

Demonstration of On-line Desalination for LC-MS Using Phosphate Adsorption onto TiO2-coated Magnetic Microparticles within a Microchannel
International Journal of Mass Spectrometry,306(1):37-43 2011(Sep.)
Author:Y. Akiyama, Y. Takahashi, I. Akutagawa, A. Ono, K. Morishima, K. Chiba

Label-free cell aggregate formation based on the magneto-Archimedes effect
,98:1673702 2011(Apr.)
Author:Y. Akiyama, K. Morishima

Electrical stimulation of cultured lepidopteran dorsal vessel tissue: an experiment for development of bioactuators.
In vitro cellular & developmental biology. Animal,46:411-415 2010(May)
Author:Akiyama Y, Iwabuchi K, Furukawa Y, Morishima K

Rod-shaped Tissue Engineered Skeletal Muscle with Artificial Anchors to Utilize as a Bio-Actuator
Journal of Biomechanical Science and Engineering,5(3):236-244 2010(Apr. 12)
Author:Y. Akiyama, R. Terada, M. Hashimot, T. Hoshino, Y. Furukawa, K. Morishima

Fabrication and evaluation of reconstructed cardiac tissue and its application to bio-actuated microdevices.
IEEE transactions on nanobioscience,8(4):349-355 2009(Dec.)
Author:Horiguchi H, Imagawa K, Hoshino T, Akiyama Y, Morishima K

Long-term and room temperature operable bioactuator powered by insect dorsal vessel tissue.
Lab on a chip,9:140-144 2009(Jan.)
Author:Akiyama Y, Iwabuchi K, Furukawa Y, Morishima K

日本ロボット学会誌,26(6):667-673 2008(Sep.)

Culture of insect cells contracting spontaneously; research moving toward an environmentally robust hybrid robotic system.
Journal of biotechnology,133(2):261-266 2008(Jan.)
Author:Akiyama Y, Iwabuchi K, Furukawa Y, Morishima K

Development of an NMR interface microchip "MICCS" for direct detection of reaction products and intermediates of micro-syntheses using a "MICCS-NMR".
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry,23(4):395-400 2007(Apr.)
Author:Takahashi Y, Nakakoshi M, Sakurai S, Akiyama Y, Suematsu H, Utsumi H, Kitamori T

Rapid bonding of Pyrex glass microchips.
Electrophoresis,28(6):994-1001 2007(Mar.)
Author:Akiyama Y, Morishima K, Kogi A, Kikutani Y, Tokeshi M, Kitamori T

相対的反磁性を利用した任意形状 2 次元細胞パターニングに向けた磁気走査条件の検討
計測自動制御学会 , 第19回計測自動制御学会システムインテグレーション部門講演会 , :2D1-07 2018(Dec. 15)
Author:菱田 豊,秋山 佳丈

Aggregation of charged microgels by relatively diamagnetic assembly
29th 2018 International Symposium on Micro-NanoMechatronics and Human Science (MHS) , :228 2018(Dec. 11)
Author:H. Suenaga, H. Minato, D. Suzuki, Y. Akiyama

日本機械学会 , 2018年度年次大会 , :J1510304 2018(Sep. 12)
Author:遠藤 佑真,秋山 佳丈

日本機械学会 , 2018年度年次大会 , :J1510303 2018(Sep. 12)
Author:菱田 豊,秋山 佳丈

日本機械学会 , 2018年度年次大会 , :J0220104 2018(Sep. 11)

日本生物工学会 , 第70回日本生物工学会大会 , :173 2018(Sep. 06)
Author:中野 翔太, 瀧澤 秀世, 秋山 佳丈

日本生物工学会 , 第70回日本生物工学会大会 , :172 2018(Sep. 06)
Author:渡部 広機,瀧澤 秀世,山田 茂,諫田 康成,秋山 佳丈

Atmospheric-operable bioactuator powered by insect cells
40th International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBS) , :16. Bio-hybrid organic machines 2018(Jul. 17)
Author:Y. Akiyama

信州ロボット研究会 , :No. 2 2018(Mar. 05)

信州ロボット研究会 , :No. 1 2018(Mar. 05)
Author:遠藤 佑真,瀧澤 秀世,秋山 佳丈

計測自動制御学会 , 第18回 計測自動制御学会システムインテグレーション部門講演会 , :1A2-06 2017(Dec. 20)
Author:遠藤 佑真,瀧澤 秀世,秋山 佳丈

Direct bioactuator formation on microstructure by quasi-diamagnetic assembly
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS2017) , :317-318 2017(Oct. 23)
Author:H. Suenaga, J. Sugihara, M. Horie, Y. Akiyama

化学とマイクロ・ナノシステム学会 , 化学とマイクロ・ナノシステム学会 第36回研究会 , :3P10 2017(Oct. 05)
Author:菱田 豊,秋山 佳丈

日本生体医工学会 , 生体医工学シンポジウム2017 , :1A-38 2017(Sep. 15)
Author:菱田 豊,秋山 佳丈

日本生物工学会 , 2017年度年次大会 , :4P-1180 2017(Sep. 14)

日本機械学会 , 2017年度年次大会 , :J0270102 2017(Sep. 05)
Author:篠瀬 真人,秋山 佳丈

日本機械学会 , ロボティクス・メカトロニクス 講演会 2017 , :2P2-O05 2017(May 12)
Author:菱田 豊,秋山 佳丈

日本機械学会 , ロボティクス・メカトロニクス 講演会 2017 , :2A1-G04 2017(May 12)

Label-free electromagnetic spheroid manipulation basedon the magneto-archimedes effect
27th 2016 International Symposium on Micro-NanoMechatronics and Human Science (MHS) , :269 2016(Nov. 30)
Author:Y. Akiyama, A. Watanabe

Cell viability in flash freezing method after cryopreservation
29th International Microprocesses and Nanotechnology Conference (MNC2016) , :10P-7-61 2016(Nov. 10)
Author:M. Shinose, A. Ueno, S. Yamaguchi, Y. Akiyama

Direct muscle tissue formation between micropillars by label-free magnetic assembly
20st International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS2016) , :383-384 2016(Oct. 09)
Author:Y. Akiyama, J. Sugihara

Influence of droplet size to cell viability in flash freezing method
26th 2015 International Symposium on Micro-NanoMechatronics and Human Science (MHS) , :123-124 2015(Nov. 23)
Author:M. Shinose, A. Ueno, S. Yamaguchi, Y. Akiyama

Assessment of 3D cell assembly system using electromagnets based on the magneto-Archimedes effect
International Conference on Biofabrication 2015 , :F4.5 2015(Nov. 07)
Author:Y. Akiyama

Three-dimensional biofabrication toward biohybrid microdevices
The 15th International Union of Materials Research Societies, International Conference in Asia (IUMRS-ICA) , :D8-I28-013 2014(Aug. 28)
Author:Y. Akiyama


2014 , Biology 1
2014 , Biomedical Microdevices
2014 , Introduction to Biorobotics
2014 , Cell Biology