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KUWAHARA Koichiro

Academic OrganizationAcademic Assembly School of Medicine and Health Sciences Institute of MedicineTEL
Education and Research OrganizationSchool of Medicine Department of Medicine (Cardiovascular)FAX
PositionProfessorMail Address
Address3-1-1, Asahi, Matsumoto City 390-8621Web site

Profile

Research Field
Cardiovascular Medicine, Molecular Cardiology,Cardiovascular Endocrinology and Metabolism

Research

Books, Articles, etc.
Articles
Predictive Value of Underweight Status for Patients With Peripheral Artery Disease With Claudication
ANGIOLOGY,69(6):513-522 2018(Jul.)
Author:Senda, Keisuke; Miura, Takashi; Minamisawa, Masatoshi; Ueki, Yasushi; Mochidome, Tomoaki; Nomi, Hidetomo; Shoin, Wataru; Higuchi, Satoko; Oguchi, Yasutaka; Nishimura, Hitoshi; Saigusa, Tatsuya; Ebisawa, Soichiro; Motoki, Hirohiko; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;


Geriatric Nutritional Risk Index Predicts Cardiovascular Events in Patients at Risk for Heart Failure
CIRCULATION JOURNAL,82(6):1614-+ 2018(Jun.)
Author:Minamisawa, Masatoshi; Miura, Takashi; Motoki, Hirohiko; Ueki, Yasushi; Nishimura, Hitoshi; Shimizu, Kunihiko; Shoin, Wataru; Harada, Mikiko; Mochidome, Tomoaki; Senda, Keisuke; Yoshie, Koji; Oguchi, Yasutaka; Hashizume, Naoto; Abe, Naoyuki; Saigusa, Tatsuya; Ebisawa, Soichiro; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;


Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report
CLINICAL BIOCHEMISTRY,52:148-152 2018(Feb.)
Author:Nakagawa, Yasuaki; Nishikimi, Toshio; Sakai, Hiroshi; Ohno, Seiko; Kinoshita, Hideyuki; Inazumi, Hideaki; Moriuchi, Kenji; Kuwahara, Koichiro; Horie, Minoru; Kimura, Takeshi;


Single-center experience with percutaneous lead extraction of cardiac implantable electric devices
JOURNAL OF CARDIOLOGY,71(1-2):192-196 2018
Author:Okada, Ayako; Shoda, Morio; Tabata, Hiroaki; Shoin, Wataru; Kobayashi, Hideki; Okano, Takahiro; Yoshie, Koji; Oguchi, Yasutaka; Takeuchi, Takahiro; Kato, Ken; Kuwahara, Koichiro;


CHARACTERISTIC AND CLINICAL OUTCOMES IN PATIENTS WITH LEFT VENTRICULAR NONCOMPACTION IN ADULTS: A NATIONWIDE SURVEY IN JAPAN
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,71(11):714-714 2018
Author:Minamisawa, Masatoshi; Koyama, Jun; Kuwahara, Koichiro; Ikeda, Uichi;


Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death
PLOS ONE,13(3):- 2018
Author:Fujii, Toshihito; Hirota, Keisho; Yasoda, Akihiro; Takizawa, Akiko; Morozumi, Naomi; Nakamura, Ryuichi; Yotsumoto, Takafumi; Kondo, Eri; Yamashita, Yui; Sakane, Yoriko; Kanai, Yugo; Ueda, Yohei; Yamauchi, Ichiro; Yamanaka, Shigeki; Nakao, Kazumasa; Kuwahara, Koichiro; Jindo, Toshimasa; Furuya, Mayumi; Mashimo, Tomoji; Inagaki, Nobuya; Serikawa, Tadao; Nakao, Kazuwa;


Prognostic Value of Ankle-Brachial Index in Patients Undergoing Percutaneous Coronary Intervention: In-Hospital and 1-Year Outcomes From the SHINANO Registry
ANGIOLOGY,68(10):884-892 2017(Nov.)
Author:Hashizume, Naoto; Miura, Takashi; Miyashita, Yusuke; Motoki, Hirohiko; Ebisawa, Soichiro; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro; SHINANO Registry Investigators;


Cardiac hyaluronan may be associated with the persistence of atrial fibrillation
HEART AND VESSELS,32(9):1144-1150 2017(Sep.)
Author:Okada, Ayako; Kashima, Yuichiro; Tomita, Takeshi; Takeuchi, Takahiro; Oguchi, Yasutaka; Yoshie, Koji; Shoin, Wataru; Shoda, Morio; Nitta, Kenichi; Kuwahara, Koichiro; Imamura, Hiroshi;


Efficacy and Safety of an Orally Administered Selective Prostacyclin Receptor Agonist, Selexipag, in Japanese Patients With Pulmonary Arterial Hypertension
CIRCULATION JOURNAL,81(9):1360-1367 2017(Sep.)
Author:Tanabe, Nobuhiro; Ikeda, Satoshi; Tahara, Nobuhiro; Fukuda, Keiichi; Hatano, Masaru; Ito, Hiroshi; Nakayama, Tomotaka; Anzai, Toshihisa; Hashimoto, Akiyoshi; Inoue, Teruo; Kajinami, Kouji; Kihara, Yasuki; Kinoshita, Hideyuki; Kuwahara, Koichiro; Murohara, Toyoaki; Okazaki, Osamu; Sakai, Satoshi; Satoh, Toru; Takeda, Yutaka; Takeishi, Yasuchika; Taniguchi, Mitsugu; Watanabe, Hiroshi; Yamamoto, Takeshi; Yamauchi-Takihara, Keiko; Yoshioka, Koichiro; Sasayama, Shigetake;


B-Type Natriuretic Peptide in Heart Failure With Preserved Ejection Fraction
CIRCULATION JOURNAL,81(7):1006-+ 2017(Jul.)
Author:Harada, Eisaku; Mizuno, Yuji; Kugimiya, Fumihito; Shono, Makoto; Maeda, Hiroyuki; Yano, Naotsugu; Kuwahara, Koichiro; Yasue, Hirofumi;


Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model
JOURNAL OF VASCULAR SURGERY,65(6):1803-1812 2017(Jun.)
Author:Setozaki, Shuji; Minakata, Kenji; Masumoto, Hidetoshi; Hirao, Shingo; Yamazaki, Kazuhiro; Kuwahara, Koichiro; Ikeda, Tadashi; Sakata, Ryuzo;


Kyoto Congestive Heart Failure (KCHF) study: rationale and design
ESC Heart Failure,4(3):216-223 2017(Feb. 17)
Author:Yamamoto, Erika; Kato, Takao; Ozasa, Neiko; Yaku, Hidenori; Inuzuka, Yasutaka; Tamaki, Yodo; Kitai, Takeshi; Morimoto, Takeshi; Taniguchi, Ryoji; Iguchi, Moritake; Kato, Masashi; Takahashi, Mamoru; Jinnai, Toshikazu; Ikeda, Tomoyuki; Nagao, Kazuya; Kawai, Takafumi; Komasa, Akihiro; Nishikawa, Ryusuke; Kawase, Yuichi; Morinaga, Takashi; Kawashima, Tsuneaki; Motohashi, Yasuyo; Kawato, Mitsunori; Toyofuku, Mamoru; Sato, Yukihito; Kuwahara, Koichiro; Shioi, Tetsuo; Kimura, Takeshi


MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts
JOURNAL OF THE AMERICAN HEART ASSOCIATION,6(2) 2017(Feb. 10)
Author:Nakagawa, Yasuaki; Nishikimi, Toshio; Kuwahara, Koichiro; Fujishima, Aoi; Oka, Shogo; Tsutamoto, Takayoshi; Kinoshita, Hideyuki; Nakao, Kazuhiro; Cho, Kosai; Inazumi, Hideaki; Okamoto, Hiroyuki; Nishida, Motohiro; Kato, Takao; Fukushima, Hiroyuki; Yamashita, Jun K.; Wijnen, Wino J.; Creemers, Esther E.; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa; Kimura, Takeshi


Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity.
Hypertension,69(2):286-296 2017(Feb.)
Author:Nakao K, Kuwahara K, Nishikimi T, Nakagawa Y, Kinoshita H, Minami T, Kuwabara Y, Yamada C, Yamada Y, Tokudome T, Nagai-Okatani C, Minamino N, Nakao YM, Yasuno S, Ueshima K, Sone M, Kimura T, Kangawa K, Nakao K.


Increase of Total Nephron Albumin Filtration and Reabsorption in Diabetic Nephropathy.
J Am Soc Nephrol,28(1):278-289 2017(Jan.)
Author:Mori KP, Yokoi H, Kasahara M, Imamaki H, Ishii A, Kuwabara T, Koga K, Kato Y, Toda N, Ohno S, Kuwahara K, Endo T, Nakao K, Yanagita M, Mukoyama M, Mori K.


2-Year Natural History of Lower Limbs in Patients With End-stage Renal Disease on Hemodialysis Due to Diabetic Nephropathy; From PREDICT Study
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY,70(18):B71-B71 2017
Author:Kato, Tamon; Miyashita, Yusuke; Miura, Takashi; Ebisawa, Souitirou; Saigusa, Tatsuya; Kuwahara, Koichiro;


Ankle-brachial Index for the Prognosis of Cardiovascular Disease in Patients with Mild Renal Insufficiency
INTERNAL MEDICINE,56(16):2103-2111 2017
Author:Nishimura, Hitoshi; Miura, Takashi; Minamisawa, Masatoshi; Ueki, Yasushi; Abe, Naoyuki; Hashizume, Naoto; Mochidome, Tomoaki; Harada, Mikiko; Shimizu, Kunihiko; Shoin, Wataru; Yoshie, Koji; Oguchi, Yasutaka; Ebisawa, Soichiro; Motoki, Hirohiko; Izawa, Atsushi; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;


Impressive predictive value of ankle-brachial index for very long-term outcomes in patients with cardiovascular disease: IMPACT-ABI study
PLOS ONE,12(6):- 2017
Author:Miura, Takashi; Minamisawa, Masatoshi; Ueki, Yasushi; Abe, Naoyuki; Nishimura, Hitoshi; Hashizume, Naoto; Mochidome, Tomoaki; Harada, Mikiko; Oguchi, Yasutaka; Yoshie, Koji; Shoin, Wataru; Saigusa, Tatsuya; Ebisawa, Soichiro; Motoki, Hirohiko; Koyama, Jun; Ikeda, Uichi; Kuwahara, Koichiro;


Diagnostic advantage of stress computed tomography myocardial perfusion over single-photon emission computed tomography for the assessment of myocardial ischemia
JOURNAL OF CARDIOLOGY,70(1-2):147-154 2017
Author:Ueki, Yasushi; Izawa, Atsushi; Kashiwagi, Daisuke; Nishiyama, Shigeki; Aso, Shinichi; Suzuki, Chihiro; Sakurai, Shumpei; Oguchi, Kazuhiro; Yazaki, Yoshikazu; Ikeda, Uichi; Kuwahara, Koichiro;


Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model
SCIENTIFIC REPORTS,7:- 2017
Author:Ogasawara, Tatsuki; Okano, Satomi; Ichimura, Hajime; Kadota, Shin; Tanaka, Yuki; Minami, Itsunari; Uesugi, Motonari; Wada, Yuko; Saito, Naoto; Okada, Kenji; Kuwahara, Koichiro; Shiba, Yuji;


TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.
Sci Rep,6:39383 2016(Dec.)
Author:Numaga-Tomita T, Kitajima N, Kuroda T, Nishimura A, Miyano K, Yasuda S, Kuwahara K, Sato Y, Ide T, Birnbaumer L, Sumimoto H, Mori Y, Nishida M.


Brain Natriuretic Peptide Counteracting the Renin-angiotensin-aldosterone System in Accelerated Malignant Hypertension.
Am J Med Sci,352(5):534-539 2016(Nov.)
Author:Nakagawa H, Mizuno Y, Harada E, Morikawa Y, Kuwahara K, Saito Y, Yasue H.


TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling.
Sci Rep,6:37001 2016(Nov.)
Author:Kitajima N, Numaga-Tomita T, Watanabe M, Kuroda T, Nishimura A, Miyano K, Yasuda S, Kuwahara K, Sato Y, Ide T, Birnbaumer L, Sumimoto H, Mori Y, Nishida M.


Brain-specific natriuretic peptide receptor-B deletion attenuates high-fat diet-induced visceral and hepatic lipid deposition in mice.
Peptides,81:38-50 2016(Jul.)
Author:Yamashita Y, Yamada-Goto N, Katsuura G, Ochi Y, Kanai Y, Miyazaki Y, Kuwahara K, Kanamoto N, Miura M, Yasoda A, Ohinata K, Inagaki N, Nakao K.


Prevention of abdominal aortic aneurysm progression by oral administration of green tea polyphenol in a rat model.
J Vasc Surg,in press 2016(Jul.)
Author:Setozaki S, Minakata K, Masumoto H, Hirao S, Yamazaki K, Kuwahara K, Ikeda T, Sakata R.


Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure.
Sci Rep,6:27192 2016(Jun.)
Author:Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, Naito M, Kuwabara T, Imamaki H, Ishii A, Saleem MA, Numata T, Mori Y, Nakao K, Yanagita M, Mukoyama M.


The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy.
Cardiovasc Res,109(1):162-73 2016(Jan.)
Author:Yamada C, Kuwahara K, Yamazaki M, Nakagawa Y, Nishikimi T, Kinoshita H, Kuwabara Y, Minami T, Yamada Y, Shibata J, Nakao K, Cho K, Arai Y, Honjo H, Kamiya K, Nakao K, Kimura T.


The renin-angiotensin system promotes arrhythmogenic substrates and lethal arrhythmias in mice with non-ischaemic cardiomyopathy
CARDIOVASCULAR RESEARCH,109(1):162-173 2016
Author:Yamada, Chinatsu; Kuwahara, Koichiro; Yamazaki, Masatoshi; Nakagawa, Yasuaki; Nishikimi, Toshio; Kinoshita, Hideyuki; Kuwabara, Yoshihiro; Minami, Takeya; Yamada, Yuko; Shibata, Junko; Nakao, Kazuhiro; Cho, Kosai; Arai, Yuji; Honjo, Haruo; Kamiya, Kaichiro; Nakao, Kazuwa; Kimura, Takeshi;


Secretion of ProBNP is Regulated by Mir30-GALNTs Axis Dependent O-linked Glycosylation in the Pathological Myocardium
CIRCULATION,134:- 2016
Author:Nakagawa, Yasuaki; Kuwahara, Koichiro; Nishikimi, Toshio; Kinoshita, Hideyuki; Inazumi, Hideki; Moriuchi, Kenji; Kato, Takao; Minamino, Naoto; Nacho, Kazuwa; Kimura, Takeshi;


Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O-glycosylation and cleavage sites.
Am J Physiol Regul Integr Comp Physiol,309(6):R639-49 2015(Sep.)
Author:Nishikimi T, Nakagawa Y, Minamino N, Ikeda M, Tabei K, Fujishima A, Takayama K, Akimoto K, Yamada C, Nakao K, Minami T, Kuwabara Y, Kinoshita H, Tsutamoto T, Ishimitsu T, Kangawa K, Kuwahara K, Nakao K.


The organ-protective effect of N-type Ca(2+) channel blockade.
Pharmacol Ther,151:1-7 2015(Jul.)
Author:Kuwahara K, Kimura T.


The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth.
Sci Rep,5:10554 2015(May)
Author:Nakao K, Osawa K, Yasoda A, Yamanaka S, Fujii T, Kondo E, Koyama N, Kanamoto N, Miura M, Kuwahara K, Akiyama H, Bessho K, Nakao K.


Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2.
J Mol Cell Cardiol,80:81-9 2015(Mar.)
Author:Oshita K, Itoh M, Hirashima S, Kuwabara Y, Ishihara K, Kuwahara K, Nakao K, Kimura T, Nakamura K, Ushijima K, Takano M.


Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model.
Sci Rep,5:7826 2015(Jan.)
Author:Tanaka M, Yamaguchi S, Yamazaki Y, Kinoshita H, Kuwahara K, Nakao K, Jay PY, Noda T, Nakamura T.


Differential Relationships Between Anemia and Outcome in Subgroups of Patients With Chronic Heart Failure.
Circ J,79(9):1893-4 2015
Author:Nakagawa Y, Yasuno S, Kuwahara K.


The Effects of Super-Flux (High Performance) Dialyzer on Plasma Glycosylated Pro-B-Type Natriuretic Peptide (proBNP) and Glycosylated N-Terminal proBNP in End-Stage Renal Disease Patients on Dialysis
PLOS ONE,9(3) 2014(Mar. 25)
Author:Nakagawa, Yasuaki; Nishikimi, Toshio; Kuwahara, Koichiro; Yasuno, Shinji; Kinoshita, Hideyuki; Kuwabara, Yoshihiro; Nakao, Kazuhiro; Minami, Takeya; Yamada, Chinatsu; Ueshima, Kenji; Ikeda, Yoshihiro; Okamoto, Hiroyuki; Horii, Kazukiyo; Nagata, Kiyoshi; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa


Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure
CARDIOVASCULAR RESEARCH,104(1):183-193 2014
Author:Yamada, Yuko; Kinoshita, Hideyuki; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kuwabara, Yoshihiro; Minami, Takeya; Yamada, Chinatsu; Shibata, Junko; Nakao, Kazuhiro; Cho, Kosai; Arai, Yuji; Yasuno, Shinji; Nishikimi, Toshio; Ueshima, Kenji; Kamakura, Shiro; Nishida, Motohiro; Kiyonaka, Shigeki; Mori, Yasuo; Kimura, Takeshi; Kangawa, Kenji; Nakao, Kazuwa;


Angiotensin II type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy
BRITISH JOURNAL OF PHARMACOLOGY,170(7):1384-1395 2013(Dec.)
Author:Yasuno, Shinji; Kuwahara, Koichiro; Kinoshita, Hideyuki; Yamada, Chinatsu; Nakagawa, Yasuaki; Usami, Satoru; Kuwabara, Yoshihiro; Ueshima, Kenji; Harada, Masaki; Nishikimi, Toshio; Nakao, Kazuwa;


Adrenomedullin in Cardiovascular Disease: A Useful Biomarker, its Pathological Roles and Therapeutic Application
CURRENT PROTEIN & PEPTIDE SCIENCE,14(4):256-267 2013(Jun.)
Author:Nishikimi, Toshio; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kangawa, Kenji; Nakao, Kazuwa;


Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts
JOURNAL OF THE AMERICAN HEART ASSOCIATION,2(3):- 2013(Jun.)
Author:Kuwabara, Yoshihiro; Kuwahara, Koichiro; Takano, Makoto; Kinoshita, Hideyuki; Arai, Yuji; Yasuno, Shinji; Nakagawa, Yasuaki; Igata, Sachiyo; Usami, Satoru; Minami, Takeya; Yamada, Yuko; Nakao, Kazuhiro; Yamada, Chinatsu; Shibata, Junko; Nishikimi, Toshio; Ueshima, Kenji; Nakao, Kazuwa;


Complexity of molecular forms of B-type natriuretic peptide in heart failure
HEART,99(10):677-679 2013(May)
Author:Nishikimi, Toshio; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa;


Direct Immunochemiluminescent Assay for proBNP and Total BNP in Human Plasma proBNP and Total BNP Levels in Normal and Heart Failure
PLOS ONE,8(1):- 2013
Author:Nishikimi, Toshio; Okamoto, Hiroyuki; Nakamura, Masahiro; Ogawa, Naoko; Horii, Kazukiyo; Nagata, Kiyoshi; Nakagawa, Yasuaki; Kinoshita, Hideyuki; Yamada, Chinatsu; Nakao, Kazuhiro; Minami, Takeya; Kuwabara, Yoshihiro; Kuwahara, Koichiro; Masuda, Izuru; Kangawa, Kenji; Minamino, Naoto; Nakao, Kazuwa;


Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,434(2):210-216 2013
Author:Nishida, Motohiro; Ishikawa, Tatsuya; Saiki, Shota; Sunggip, Caroline; Aritomi, Shizuka; Harada, Eri; Kuwahara, Koichiro; Hirano, Katsuya; Mori, Yasuo; Kim-Mitsuyama, Shokei;


Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice
EMBO JOURNAL,31(23):4428-4440 2012
Author:Minami, Takeya; Kuwahara, Koichiro; Nakagawa, Yasuaki; Takaoka, Minoru; Kinoshita, Hideyuki; Nakao, Kazuhiro; Kuwabara, Yoshihiro; Yamada, Yuko; Yamada, Chinatsu; Shibata, Junko; Usami, Satoru; Yasuno, Shinji; Nishikimi, Toshio; Ueshima, Kenji; Sata, Masataka; Nakano, Hiroyasu; Seno, Takahiro; Kawahito, Yutaka; Sobue, Kenji; Kimura, Akinori; Nagai, Ryozo; Nakao, Kazuwa;


Zinc-finger protein 90 negatively regulates neuron-restrictive silencer factor-mediated transcriptional repression of fetal cardiac genes
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,50(6):972-981 2011(Jun.)
Author:Hata, Leo; Murakami, Masao; Kuwahara, Koichiro; Nakagawa, Yasuaki; Kinoshita, Hideyuki; Usami, Satoru; Yasuno, Shinji; Fujiwara, Masataka; Kuwabara, Yoshihiro; Minami, Takeya; Yamada, Yuko; Yamada, Chinatsu; Nakao, Kazuhiro; Ueshima, Kenji; Nishikimi, Toshio; Nakao, Kazuwa;


Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A
PLOS ONE,6(2):- 2011
Author:Fujiwara, Masataka; Yan, Peishi; Otsuji, Tomomi G.; Narazaki, Genta; Uosaki, Hideki; Fukushima, Hiroyuki; Kuwahara, Koichiro; Harada, Masaki; Matsuda, Hiroyuki; Matsuoka, Satoshi; Okita, Keisuke; Takahashi, Kazutoshi; Nakagawa, Masato; Ikeda, Tadashi; Sakata, Ryuzo; Mummery, Christine L.; Nakatsuji, Norio; Yamanaka, Shinya; Nakao, Kazuwa; Yamashita, Jun K.;


Pathophysiological Remodeling of Mouse Cardiac Myocytes Expressing Dominant Negative Mutant of Neuron Restrictive Silencing Factor
CIRCULATION JOURNAL,74(12):2712-2719 2010(Dec.)
Author:Takano, Makoto; Kinoshita, Hideyuki; Shioya, Takao; Itoh, Masayuki; Nakao, Kazuwa; Kuwahara, Koichiro;


Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression
MOLECULAR AND CELLULAR BIOLOGY,30(17):4134-4148 2010(Sep.)
Author:Kuwahara, Koichiro; Kinoshita, Hideyuki; Kuwabara, Yoshihiro; Nakagawa, Yasuaki; Usami, Satoru; Minami, Takeya; Yamada, Yuko; Fujiwara, Masataka; Nakao, Kazuwa;


Podocyte-specific expression of tamoxifen-inducible Cre recombinase in mice
NEPHROLOGY DIALYSIS TRANSPLANTATION,25(7):2120-2124 2010(Jul.)
Author:Yokoi, Hideki; Kasahara, Masato; Mukoyama, Masashi; Mori, Kiyoshi; Kuwahara, Koichiro; Fujikura, Junji; Arai, Yuji; Saito, Yoko; Ogawa, Yoshihisa; Kuwabara, Takashige; Sugawara, Akira; Nakao, Kazuwa;


Regulation and significance of atrial and brain natriuretic peptides as cardiac hormones
ENDOCRINE JOURNAL,57(7):555-565 2010(Jul.)
Author:Kuwahara, Koichiro; Nakao, Kazuwa;


Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart
CIRCULATION RESEARCH,106(12):1849-U153 2010
Author:Kinoshita, Hideyuki; Kuwahara, Koichiro; Nishida, Motohiro; Jian, Zhong; Rong, Xianglu; Kiyonaka, Shigeki; Kuwabara, Yoshihiro; Kurose, Hitoshi; Inoue, Ryuji; Mori, Yasuo; Li, Yuhao; Nakagawa, Yasuaki; Usami, Satoru; Fujiwara, Masataka; Yamada, Yuko; Minami, Takeya; Ueshima, Kenji; Nakao, Kazuwa;


Myocardin-Related Transcription Factor-A Controls Myofibroblast Activation and Fibrosis in Response to Myocardial Infarction
CIRCULATION RESEARCH,107(2):294-U263 2010
Author:Small, Eric M.; Thatcher, Jeffrey E.; Sutherland, Lillian B.; Kinoshita, Hideyuki; Gerard, Robert D.; Richardson, James A.; DiMaio, J. Michael; Sadek, Hesham; Kuwahara, Koichiro; Olson, Eric N.;


Guanylyl Cyclase-A Inhibits Angiotensin II Type 2 Receptor-Mediated Pro-Hypertrophic Signaling in the Heart
ENDOCRINOLOGY,150(8):3759-3765 2009(Aug.)
Author:Li, Yuhao; Saito, Yoshihiko; Kuwahara, Koichiro; Rong, Xianglu; Kishimoto, Ichiro; Harada, Masaki; Adachi, Yuichiro; Nakanishi, Michio; Kinoshita, Hideyuki; Horiuchi, Masatsugu; Murray, Michael; Nakao, Kazuwa;


The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2
CARDIOVASCULAR RESEARCH,83(4):682-687 2009
Author:Kuratomi, Shinobu; Ohmori, Yoko; Ito, Masayuki; Shimazaki, Kuniko; Muramatsu, Shin-ichi; Mizukami, Hiroaki; Uosaki, Hideki; Yamashita, Jun K.; Arai, Yuji; Kuwahara, Koichiro; Takano, Makoto;


T-Type Ca2+ Channel Blockade Prevents Sudden Death in Mice With Heart Failure
CIRCULATION,120(9):743-U66 2009
Author:Kinoshita, Hideyuki; Kuwahara, Koichiro; Takano, Makoto; Arai, Yuji; Kuwabara, Yoshihiro; Yasuno, Shinji; Nakagawa, Yasuaki; Nakanishi, Michio; Harada, Masaki; Fujiwara, Masataka; Murakami, Masao; Ueshima, Kenji; Nakao, Kazuwa;


p300 Plays a Critical Role in Maintaining Cardiac Mitochondrial Function and Cell Survival in Postnatal Hearts
CIRCULATION RESEARCH,105(8):746-U57 2009
Author:Nakagawa, Yasuaki; Kuwahara, Koichiro; Takemura, Genzo; Akao, Masaharu; Kato, Masashi; Arai, Yuji; Takano, Makoto; Harada, Masaki; Murakami, Masao; Nakanishi, Michio; Usami, Satoru; Yasuno, Shinji; Kinoshita, Hideyuki; Fujiwara, Masataka; Ueshima, Kenji; Nakao, Kazuwa;


Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitation
CIRCULATION JOURNAL,71(8):1310-1316 2007(Aug.)
Author:Nakanishi, Michio; Harada, Masaki; Kishimoto, Ichiro; Kuwahara, Koichiro; Kawakami, Rika; Nakagawa, Yasuaki; Yasuno, Shinji; Usami, Satoru; Kinoshita, Hideyuki; Adachi, Yuichiro; Fukamizu, Akiyoshi; Saito, Yoshihiko; Nakao, Kazuwa;


Modulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activity
JOURNAL OF CLINICAL INVESTIGATION,117(5):1324-1334 2007(May)
Author:Kuwahara, Koichiro; Pipes, Gordon C. Teg; McAnally, John; Richardson, James A.; Hill, Joseph A.; Bassel-Duby, Rhonda; Olson, Eric N.;


Two novel members of the ABLIM protein family, ABLIM-2 and -3, associate with STARS and directly bind F-actin
JOURNAL OF BIOLOGICAL CHEMISTRY,282(11):8393-8403 2007
Author:Barrientos, Tomasa; Frank, Derk; Kuwahara, Koichiro; Bezprozvannaya, Svetlana; Pipes, G. C. Teg; Bassel-Duby, Rhonda; Richardson, James A.; Katus, Hugo A.; Olson, Eric N.; Frey, Norbert;


Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance
CIRCULATION,116(2):E25-E26 2007
Author:Nakanishi, Michio; Harada, Masaki; Tadamura, Eiji; Kotani, Hirokazu; Kawakami, Rika; Kuwahara, Koichiro; Nakagawa, Yasuaki; Usami, Satoru; Kinoshita, Hideyuki; Fujiwara, Masataka; Hosoda, Kiminori; Ueshima, Kenji; Nakao, Kazuwa;


TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
JOURNAL OF CLINICAL INVESTIGATION,116(12):3114-3126 2006(Dec.)
Author:Kuwahara, Koichiro; Wang, Yanggan; McAnally, John; Richardson, James A.; Bassel-Duby, Rhonda; Hill, Joseph A.; Olson, Eric N.;


Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY,41(6):1010-1022 2006(Dec.)
Author:Nakagawa, Yasuaki; Kuwahara, Koichiro; Harada, Masaki; Takahashi, Nobuki; Yasuno, Shinji; Adachi, Yuichiro; Kawakami, Rika; Nakanishi, Michio; Tanimoto, Keiji; Usami, Satoru; Kinoshita, Hideyuki; Saito, Yoshihiko; Nakao, Kazuwa;