医学博士, 信州大学

Gastroenterology, Hepatology

Successful treatment by glecaprevir/pibrentasvir followed by hepatoprotective therapy of acute chronic hepatitis exacerbation caused by daratumumab-based regimen for multiple myeloma: Case report and review of the literature
Yamazaki T, Joshita S, Ichijo T, Kobayashi H, Wakabayashi SI, Yamashita Y, Sugiura A, Kawakami F, Nakazawa H, Umemura T
J Infect Chemother, 27(12), 1750-1755, Dec. 2021
Lead

A Case of Liver Metastasis in Primary Renal Cell Carcinoma Diagnosed by Hepatectomy after 9 Years of Follow-up of Cystic Liver Lesion
SHIMIZU Yuki, SUGIURA Ayumi, JOSHITA Satoru, KOBAYASHI Hiroyuki, WAKABAYASHI Shun-ichi, YAMASHITA Yuki, YAMAZAKI Tomoo, UEHARA Takeshi, SHIMIZU Akira, SOEJIMA Yuji,UMEMURA Takeji
The Shinshu Medical Journal, 69(4), 209-215, Aug. 2021

Adult Case of Acute Hepatitis Associated with Primary Cytomegalovirus Infection in Remission Phase of Crohn's Disease
YAMAZAKI Tomoo, JOSHITA Satoru, OHNO Kazuyuki, SUGA Tomoaki, KOBAYASHI Hiroyuki, WAKABAYASHI Shun-ichi, YAMASHITA Yuki, SUGIURA Ayumi, UMEMURA Takeji
The Shinshu Medical Journal, 69(3), 127-133, Jun. 2021

Clinical utility of FibroScan as a non-invasive diagnostic test for primary biliary cholangitis
Joshita, Satoru; Yamashita, Yuki; Sugiura, Ayumi; Uehara, Takeshi; Usami, Yoko; Yamazaki, Tomoo; Fujimori, Naoyuki; Matsumoto, Akihiro; Tanaka, Eiji; Umemura, Takeji;
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 35(7), 1208-1214, Jul. 2020

Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases
Sugiura, Ayumi; Joshita, Satoru; Yamashita, Yuki; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Wada, Shuichi; Mori, Hiromitsu; Shibata, Soichiro; Yoshizawa, Kaname; Morita, Susumu; Furuta, Kiyoshi; Kamijo, Atsushi; Iijima, Akihiro; Kako, Satoko; Maruyama, Atsushi; Kobayashi, Masakazu; Komatsu, Michiharu; Matsumura, Makiko; Miyabayashi, Chiharu; Ichijo, Tetsuya; Takeuchi, Aki; Koike, Yuriko; Gibo, Yukio; Tsukadaira, Toshihisa; Inada, Hiroyuki; Nakano, Yoshiyuki; Usuda, Seiichi; Kiyosawa, Kendo; Tanaka, Eiji; Umemura, Takeji;
BIOMEDICINES, 8(4), Apr. 2020

Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese
Suzuki, Hiroshi; Joshita, Satoru; Hirayama, Atsuhiro; Shinji, Akihiro; Mukawa, Kenji; Sako, Minako; Yoshimura, Naoki; Suga, Tomoaki; Umemura, Takeji; Ashihara, Norihiro; Yamazaki, Tomoo; Ota, Masao;
SCIENTIFIC REPORTS, 10(1), 2020

減量導入したレゴラフェニブが奏功し，12カ月以上の長期投与が可能であった多発肝細胞癌・胸椎および副腎転移の1例
岩垂 隆諒;山崎 智生;城下 智;藤森 尚之;金井 圭太;山下 裕騎;高橋 芳之;杉浦 亜弓;梅村 武司
肝臓, 61(8), 426-433, 2020

Clinical impact of normal alanine aminotransferase on direct-acting antiviral outcome in patients with chronic hepatitis C virus infection
Joshita S, Sugiura A, Umemura T, Yamazaki T, Fujimori N, Matsumoto A, Usami Y, Tanaka E.
Dec. 2019

Biochemical and plasma lipid responses to pemafibrate in patients with primary biliary cholangitis
Joshita, Satoru; Umemura, Takeji; Yamashita, Yuki; Sugiura, Ayumi; Yamazaki, Tomoo; Fujimori, Naoyuki; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 49(10), 1236-1243, Oct. 2019

Renal impairment is associated with increased risk of mortality in patients with cirrhosis: A retrospective cohort study
Umemura, Takeji; Joshita, Satoru; Shibata, Soichiro; Sugiura, Ayumi; Yamazaki, Tomoo; Fujimori, Naoyuki; Matsumoto, Akihiro; Tanaka, Eiji;
MEDICINE, 98(6), Feb. 2019

Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals
Sugiura, Ayumi; Joshita, Satoru; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Usami, Yoko; Wada, Shuichi; Mori, Hiromitsu; Shibata, Soichiro; Yoshizawa, Kaname; Morita, Susumu; Furuta, Kiyoshi; Kamijo, Atsushi; Iijima, Akihiro; Kako, Satoko; Maruyama, Atsushi; Kobayashi, Masakazu; Komatsu, Michiharu; Matsumura, Makiko; Miyabayashi, Chiharu; Ichijo, Tetsuya; Takeuchi, Aki; Koike, Yuriko; Gibo, Yukio; Tsukadaira, Toshihisa; Inada, Hiroyuki; Kiyosawa, Kendo; Tanaka, Eiji;
JOURNAL OF VIRAL HEPATITIS, 25(12), 1462-1471, Dec. 2018

Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients
Komatsu, Michiharu; Tanaka, Naoki; Kimura, Takefumi; Fujimori, Naoyuki; Sano, Kenji; Horiuchi, Akira; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 48(13), 1092-1098, Dec. 2018

Quantitative analysis of serum chemokines associated with treatment failure of direct-acting antivirals in chronic hepatitis C
Umemura, Takeji; Yamazaki, Tomoo; Joshita, Satoru; Sugiura, Ayumi; Fujimori, Naoyuki; Matsumoto, Akihiro; Ota, Masao; Tanaka, Eiji;
CYTOKINE, 111, 357-363, Nov. 2018

A case of liver abscess co-infected with Desulfovibrio desulfuricans and Escherichia coli and review of the literature
Yamazaki, Tomoo; Joshita, Satoru; Kasuga, Eriko; Horiuchi, Kazuki; Sugiura, Ayumi; Fujimori, Naoyuki; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
JOURNAL OF INFECTION AND CHEMOTHERAPY, 24(5), 393-397, May 2018

Serum autotaxin is a useful liver fibrosis marker in patients with chronic hepatitis B virus infection
Joshita, Satoru; Ichikawa, Yuki; Umemura, Takeji; Usami, Yoko; Sugiura, Ayumi; Shibata, Soichiro; Yamazaki, Tomoo; Fujimori, Naoyuki; Komatsu, Michiharu; Matsumoto, Akihiro; Igarashi, Koji; Ota, Masao; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 48(4), 275-285, Mar. 2018

Two Cases of Primary Biliary Cholangitis with Hepatocellular Carcinoma in a Non-cirrhotic Stage
SUGIURA Ayumi, JOSHITA Satoru, YAMASHITA Yuki, KIMURA Takefumi, YAMAZAKI Tomoo, FUJIMORI Naoyuki, KOMATSU Michiharu, MATSUMOTO Akihiro, KOBAYASHI Shota, UMEMURA Takeji, TANAKA Eiji
The Shinshu Medical Journal, 66(1), 39-49, Feb. 2018

A cis-eQTL of HLA-DPB1 Affects Susceptibility to Type 1 Autoimmune Hepatitis
Yamazaki, Tomoo; Umemura, Takeji; Joshita, Satoru; Yoshizawa, Kaname; Tanaka, Eiji; Ota, Masao;
SCIENTIFIC REPORTS, 8, 2018

Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis
Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Yamashita, Yuki; Norman, Gary L.; Sugiura, Ayumi; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Yoshizawa, Kaname; Ota, Masao; Tanaka, Eiji;
SCIENTIFIC REPORTS, 8, 2018

Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C
Yamazaki, Tomoo; Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Sugiura, Ayumi; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Ota, Masao; Tanaka, Eiji;
PLOS ONE, 13(4), 2018

Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis
Kimura, Takefumi; Tanaka, Naoki; Fujimori, Naoyuki; Sugiura, Ayumi; Yamazaki, Tomoo; Joshita, Satoru; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 24(13), 1440-1450, 2018

Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease
Fujimori, Naoyuki; Umemura, Takeji; Kimura, Takefumi; Tanaka, Naoki; Sugiura, Ayumi; Yamazaki, Tomoo; Joshita, Satoru; Komatsu, Michiharu; Usami, Yoko; Sano, Kenji; Igarashi, Koji; Matsumoto, Akihiro; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 24(11), 1239-1249, 2018

多発肝細胞癌・腸骨転移に対し放射線照射・肝動脈化学塞栓術・sorafenib内服を組み合わせた集学的治療を行い長期寛解が得られた1例
若林 俊一;小松 通治;梅村 武司;松本 晶博;田中 榮司;山崎 智生;城下 智;黒住 昌弘;杉浦 亜弓;藤森 尚之;柴田 壮一郎;市川 雪;森田 進
肝臓, 59(2), 117-124, 2018

Combination of Killer Immunoglobulin-like Receptor and HLA Genes is Associated with Hepatitis C Virus-Related Hepatocellular Carcinoma
Umemura, Takeji; Saito, Hiromi; Joshita, Satoru; Yamazaki, Tomoo; Tanaka, Eiji; Ota, Masao;
Oncotarget, 66, 124A-124A, Oct. 2017

Two cases of non-cirrhotic primary biliary cirrhosis with complicating hepatocellular carcinoma
Sugiura, Ayumi; Joshita, Satoru; Yamashita, Yuki; Hihara, Yu; Fujimori, Naoyuki; Yamazaki, Tomoo; Maruyama, Yasuhiro; Shibata, Souichiro; Ichikawa, Yuki; Kimura, Takefumi; Ito, Tetsuya; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
32, 186-186, Sep. 2017

Association of serum autotaxin level with disease stage in Japanese patients with primary biliary cholangitis
Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Sugiura, Ayumi; Yamazaki, Tomoo; Fujimori, Naoyuki; Komatsu, Michiharu; Matsumoto, Akihiro; Igarashi, Koji; Ota, Masao; Tanaka, Eiji;
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32, 179-179, Sep. 2017

Association between serum soluble CD14 and IL-8 levels and clinical outcome in primary biliary cholangitis
Umemura, Takeji; Sekiguchi, Tomohiro; Joshita, Satoru; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Komatsu, Michiharu; Matsumoto, Akihiro; Shums, Zakera; Norman, Gary L.; Tanaka, Eiji; Ota, Masao;
LIVER INTERNATIONAL, 37(6), 897-905, Jun. 2017

Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection
Kimura, Takefumi; Kobayashi, Akira; Tanaka, Naoki; Sano, Kenji; Komatsu, Michiharu; Fujimori, Naoyuki; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Horiuchi, Akira; Mori, Hiromitsu; Wada, Shuichi; Kiyosawa, Kendo; Miyagawa, Shin-ichi; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 47(5), 405-418, Apr. 2017

Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein may predict liver fibrosis and progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection
Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Shobugawa, Yugo; Usami, Yoko; Shibata, Soichiro; Yamazaki, Tomoo; Fujimori, Naoyuki; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 47(2), 226-233, Feb. 2017

Massive ascites caused by intra-pancreatic arterioportal fistula: a rare complication of chronic pancreatitis
Yamazaki T, Iwaya Y, Iwaya M, Watanabe T, Seki A, Ochi Y, Hara E, Sekiguchi T, Hosaka N, Arakura N, Tanaka E, Hasebe O.
Clin J Gastroenterol, 2017

Association of Serum Autotaxin Levels with Liver Fibrosis in Patients with Chronic Hepatitis C
Yamazaki, Tomoo; Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Sugiura, Ayumi; Fujimori, Naoyuki; Shibata, Soichiro; Ichikawa, Yuki; Komatsu, Michiharu; Matsumoto, Akihiro; Igarashi, Koji; Tanaka, Eiji;
SCIENTIFIC REPORTS, 7, 2017

Association between endotoxemia and histological features of nonalcoholic fatty liver disease
Kitabatake, Hiroyuki; Tanaka, Naoki; Fujimori, Naoyuki; Komatsu, Michiharu; Okubo, Ayaka; Kakegawa, Kyogo; Kimura, Takefumi; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Koinuma, Masayoshi; Sano, Kenji; Aoyama, Toshifumi; Tanaka, Eiji;
WORLD JOURNAL OF GASTROENTEROLOGY, 23(4), 712-722, 2017

Controlled attenuation parameter is correlated with actual hepatic fat content in patients with non-alcoholic fatty liver disease with none-to-mild obesity and liver fibrosis
Fujimori, Naoyuki; Tanaka, Naoki; Shibata, Soichiro; Sano, Kenji; Yamazaki, Tomoo; Sekiguchi, Tomohiro; Kitabatake, Hiroyuki; Ichikawa, Yuki; Kimura, Takefumi; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 46(10), 1019-1027, Sep. 2016

Liver stiffness-spleen size-to-platelet ratio risk score identifies esophageal varices in Japanese patients with chronic hepatitis C
Shibata, Soichiro; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
HEPATOLOGY RESEARCH, 46(9), 884-889, Aug. 2016

A case of simultaneous esophageal squamous cell carcinoma and Barrett's adenocarcinoma
Yamazaki T, Iwaya Y, Iwaya M, Watanabe T, Seki A, Ochi Y, Hara E, Sekiguchi T, Hosaka N, Arakura N, Tanaka E, Hasebe O.
Clin J Gastroenterol, 2016

Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan
Umemura, Takeji; Joshita, Satoru; Yamazaki, Tomoo; Komatsu, Michiharu; Katsuyama, Yoshihiko; Yoshizawa, Kaname; Tanaka, Eiji; Ota, Masao;
SCIENTIFIC REPORTS, 6, 2016

Liver stiffness-spleen size-to-platelet ratio risk score detects esophageal varices in chronic liver disease
Shibata, Soichiro; Joshita, Satoru; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Ichikawa, Yuki; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
Springerplus, 5, 2016