Katoh Nagaaki

School of Medicine 

Associate Professor 

Researcher Information


  • Ph. D., Shinshu University

Field Of Study

  • Hematology and medical oncology, ALアミロイドーシス

Educational Background

  • 2010 - 2012, Biochemistry and Molecular Biology Lab, Mayo Clinic, Rochester, MN, USA
Research activity information


  • Reduction of cardiac AL amyloid deposition after complete response visualised by PiB-PET imaging.
    Oguchi K, Katoh N, Mochizuki Y, Takahashi Y, Ueno A, Takasone K, Sekijima Y.
    Amyloid, 30(1), 138-139, 2023, Refereed
  • Surgical revascularization for quasi-moyamoya disease associated with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome: a case report and literature review.
    Kubota Y, Hanaoka Y, Koyama JI, Takahashi Y, Katoh N, Iwaya M, Fujii Y, Ogiwara T, Horiuchi T.
    Nagoya J Med Sci, 85(1), 141-149, 2023, Refereed
  • Daratumumab plus bortezomib, cyclophosphamide, and dexamethasone in Asian patients with newly diagnosed AL amyloidosis: subgroup analysis of ANDROMEDA.
    Suzuki K, Wechalekar AD, Kim K, Shimazaki C, Kim JS, Ikezoe T, Min CK, Zhou F, Cai Z, Chen X, Iida S, Katoh N, Fujisaki T, Shin HJ, Tran N, Qin X, Vasey SY, Tromp B, Weiss BM, Comenzo RL, Kastritis E, Lu J.
    Ann Hematol, 102(4), 863-876, 2023, Refereed
  • Distribution and progression of cerebral amyloid angiopathy in early-onset V30M (p.V50M) hereditary ATTR amyloidosis.
    Takahashi Y, Oguchi K, Mochizuki Y, Takasone K, Ezawa N, Matsushima A, Katoh N, Yazaki M, Sekijima Y.
    Amyloid, 30(1), 109-118, 2023, Refereed
  • AH amyloid neuropathy: a novel clinical phenotype confirmed by histopathology and mass spectrometry.
    Ohashi N, Katoh N, Kasuga K, Yoshinaga T, Kametani F, Yazaki M, Sekijima Y.
    Amyloid, 29(2), 141-142, 2022
  • Moyamoya Disease-like Cerebrovascular Stenotic Lesions Are an Important Phenotype of POEMS Syndrome-associated Vasculopathy.
    Takahashi Y, Mochizuki Y, Nakamura K, Katoh N, Sekijima Y.
    Intern Med, 61(10), 1603-1608, 2022
  • Somatostatin-derived amyloid deposition associated with duodenal neuroendocrine tumour (NET): a report of novel localised amyloidosis associated with NET.
    Ichimata S, Katoh N, Abe R, Yoshinaga T, Kametani F, Yazaki M, Kusama Y, Sano K, Uehara T, Sekijima Y.
    Amyloid, 29(1), 64-65, 2022
  • A Case of Transthyretin Variant Amyloidosis with a TTR A97D (p.A117D) Mutation Manifesting Remarkable Asymmetric Neuropathy.
    Ikeda K, Yamamoto D, Usui K, Takeuchi H, Oka N, Katoh N, Yazaki M, Kametani F, Nishino I, Hisahara S.
    Intern Med, Epub, 2022, Refereed
  • A case of asymmetric insulin-derived localised amyloid deposition associated with long-acting insulin analog administration.
    Hirai K, Imamura S, Hirai A, Umemoto N, Oshiro H, Kametani F, Katoh N, Yazaki M, Ookawara S, Morishita Y.
    Amyloid, 29(3), 205-207, 2022, Refereed
  • Early Detection of Cardiac Amyloidosis in Transthyretin Mutation Carriers.
    Nagano N, Muranaka A, Nishikawa R, Ohwada W, Kouzu H, Kamiyama N, Fujito T, Mochizuki A, Nagahara D, Nakanishi M, Ohkubo Y, Hisahara S, Nakao S, Katoh N, Ishikawa A, Sakurai A, Yano T.
    Int Heart J, 63(1), 168-175, 2022
  • Novel histopathological deposition patterns of EGF-containing fibulin-like extracellular matrix protein 1 amyloidosis: an autopsy case exhibiting a possible association between AEFEMP1 amyloidosis and elastic fibres.
    Ichimata S, Hata Y, Katoh N, Kametani F, Yazaki M, Sekijima Y, Nishida N.
    Amyloid, 29(2), 139-140, 2022
  • Therapeutic Outcome of Lenalidomide-dexamethasone in Patients with Relapsed or Refractory Systemic Immunoglobulin Light Chain (AL) Amyloidosis: A Single-center Analysis and Review of the Literature.
    Ueno A, Katoh N, Ezawa N, Yoshinaga T, Yazaki M, Sekijima Y.
    shinshu med J, 70(1), 29-38, 2022
  • A Rare Case of Localized Esophageal Amyloidosis
    Fujiya T, Hatta W, Koike T, Ogata Y, Saito M, Jin X, Nakagawa K, Kanno T, Asanuma K, Uno K, Asano N, Imatani A, Fujishima F, Katoh N, Yoshinaga T, Masamune A
    Intern Med, 60(10), 1529-1532, 15 May 2021
  • Hereditary Apolipoprotein A-1 Amyloidosis With Glu34Lys Mutation Treated by Liver Transplantation: A Case Report
    Sagawa T, Kogiso T, Ito T, Yasuda H, Katoh N, Yoshinaga T, Yazaki M, Kato T, Omori A, Kotera Y, Egawa H, Yamamoto M, Tokushige K
    Transplant Proc, 53(4), 1327-1332, 01 May 2021
  • Development of diagnostic antibodies against immunoglobulin heavy chain variable region for heavy chain amyloidosis (AH amyloidosis)
    Nakagawa M, Yazaki M, Kametani F, Katoh N, Yoshinaga T, Higuchi K, Sekijima Y
    Pathol Int, 71(4), 245-254, 01 Apr. 2021
  • A case of novel amyloidosis: glucagon-derived amyloid deposition associated with pancreatic neuroendocrine tumour
    Ichimata S, Katoh N, Abe R, Yoshinaga T, Kametani F, Yazaki M, Uehara T, Sekijima Y
    Amyloid, 28(1), 72-73, 01 Mar. 2021
  • Late-onset Hereditary ATTR Amyloidosis with a Novel p.P63S (P43S) Transthyretin Variant
    Aono Y, Hamatani Y, Katoh N, Nakagawa M, Nakamura K, Yazaki M, Kametani F, Iguchi M, Murakami I, Ogawa H, Abe M, Akao M, Sekijima Y
    Intern Med, 60(4), 557-561, 15 Feb. 2021
  • Giant Hepatomegaly with Spleno-testicular Enlargement in a Patient with Apolipoprotein A-I Amyloidosis: An Uncommon Type of Amyloidosis in Japan
    Yoshinaga T, Katoh N, Yazaki M, Sato M, Kametani F, Yasuda H, Watanabe K, Kawata K, Nakagawa M, Sekijima Y
    Intern Med, 60(4), 575-581, 15 Feb. 2021
  • Localized Gastric Amyloidosis that Displayed Morphological Changes over 10 Years of Observation
    Takahashi Y, Hatta W, Koike T, Ogata Y, Fujiya T, Saito M, Jin X, Nakagawa K, Kanno T, Asanuma K, Uno K, Asano N, Imatani A, Fujishima F, Katoh N, Yoshinaga T, Masamune A
    Intern Med, 60(4), 539-543, 15 Feb. 2021
  • A case of wild-type transthyretin cardiac amyloidosis with rheumatoid arthritis
    Tsuda R, Shinoda K, Ushijima R, Nakamura M, Katoh N, Imura J, Tobe K
    Mod Rheumatol Case Rep, 1-9, 18 Jan. 2021
  • Distribution of amyloidosis subtypes based on tissue biopsy site - Consecutive analysis of 729 patients at a single amyloidosis center in Japan
    Abe R, Katoh N, Takahashi Y, Takasone K, Yoshinaga T, Yazaki M, Kametani F, Sekijima Y
    Pathol Int, 71(1), 70-79, 01 Jan. 2021
  • Localized Immunoglobulin Light-Chain Amyloidosis of the Ulnar Nerve.
    Morisaki S, Tsuchida S, Konishi E, Katoh N, Takahashi Y, Takahashi K.
    Case Rep Neurol, 13, 305-311, 2021
  • Non-invasive detection and differentiation of cardiac amyloidosis using 99mTc-pyrophosphate scintigraphy and 11C-Pittsburgh compound B PET imaging
    Takasone K, Katoh N, Takahashi Y, Abe R, Ezawa N, Yoshinaga T, Yanagisawa S, Yazaki M, Oguchi K, Koyama J, Sekijima Y
    Amyloid, 27(4), 266-274, 01 Dec. 2020
  • Gray Matter Encephalomyelitis with Anti-Myelin Oligodendrocyte Glycoprotein Antibody
    Morizumi T, Takasone K, Katoh N, Sekijima Y
    Intern Med, 59(19), 2435-2436, 01 Oct. 2020
  • Insight from an autopsy in a patient with rapidly worsening heart failure due to amyloid light-chain cardiac amyloidosis: A case report
    Yokoyama H, Shishido K, Ito J, Kamata W, Katoh N, Saito S
    J Cardiol Cases, 22(2), 48-51, 13 May 2020
  • An autopsy case of amyloid tubulopathy exhibiting characteristic spheroid-type deposition.
    Ichimata S, Hata Y, Abe R, Yoshinaga T, Katoh N, Kametani F, Yazaki M, Sekijima Y, Ehara T, Nishida N.
    Virchows Arch, 13 Jan. 2020
  • Temporal artery involvement in AL amyloidosis: an important differential diagnosis for giant cell arteritis. A case report and literature review
    Oiwa H, Katoh N, Kojo S, Yoshinaga T, Taniguchi K, Shiote Y
    Mod Rheumatol Case Rep, 4(1), 90-94, 04 Jan. 2020
  • A case of spheroid-type localized lactoferrin amyloidosis in the bronchus.
    Ichimata S, Aoyagi D, Yoshinaga T, Katoh N, Kametani F, Yazaki M, Uehara T, Shiozawa S.
    Pathol Int, 69(4), 235-240, Apr. 2019
  • Heavy-chain amyloidosis in gastroduodenal biopsies - the histopathological features.
    Ichimata S, Kobayashi M, Shimojo H, Katoh N, Yazaki M, Kanno H.
    Amyloid, 26(s1), 89-90, 2019
  • Usefulness of gastroduodenal biopsy in the differential diagnosis of systemic AH amyloidosis from systemic AL amyloidosis.
    Ichimata S, Kobayashi M, Shimojo H, Katoh N, Yazaki M, Kanno H
    HISTOPATHOLOGY, 73(2), 230-239, Aug. 2018
  • A 36-year-old woman with primary central nervous system lymphoma diagnosed by twice brain biopsies, showing relapsing and remitting brain lesions.
    Takasone K, Kobayashi C, Katoh N, Kaneko T, Shingu K, Ikeda SI
    Rinsho Shinkeigaku, 58(7), 440-444, 27 Jul. 2018
  • Visualization of multiple organ amyloid involvement in systemic amyloidosis using 11C-PiB PET imaging.
    Ezawa N, Katoh N, Oguchi K, Yoshinaga T, Yazaki M, Sekijima Y.
    Eur J Nucl Med Mol Imaging, 45(3), 452-461, Mar. 2018
  • Nationwide Survey of 741 Patients with Systemic Amyloid Light-chain Amyloidosis in Japan.
    Shimazaki C, Hata H, Iida S, Ueda M, Katoh N, Sekishima Y, Ikeda S, Yazaki M, Fukushima W, Ando Y.
    Intern Med, 57(2), 181-187, 15 Jan. 2018
  • Bortezomib-dexamethasone versus high-dose melphalan for Japanese patients with systemic light-chain (AL) amyloidosis: a retrospective single-center study.
    Katoh N, Ueno A, Yoshida T, Tazawa KI, Shimojima Y, Gono T, Sekijima Y, Matsuda M, Ikeda SI.
    Int J Hematol., 105(3), 341-348, Mar. 2017
  • Acetylcholine receptor binding antibody-associated myasthenia gravis and rhabdomyolysis induced by nivolumab in a patient with melanoma.
    Shirai T, Sano T, Kamijo F, Saito N, Miyake T, Kodaira M, Katoh N, Nishie K, Okuyama R, Uhara H.
    Jpn J Clin Oncol, 46(1), 86-88, 2016
  • Liver Transplantation Is a Potential Treatment Option for Systemic Light Chain Amyloidosis Patients with Dominant Hepatic Involvement: A Case Report and Analytical Review of the Literature.
    Ueno A, Katoh N, Aramaki O, Makuuchi M, Ikeda S.
    Intern Med., 55(12), 1585-1590, 2016
  • Clinical, endoscopic, and histopathological features of localized immunoglobulin light chain (AL) amyloidosis in the gastrointestinal tract.
    Katoh N, Matsuda M, Ikeda S
    Amyloid, 22(4), 254-256, 2015
  • Regression of localized ureter amyloidosis after treatment with steroids suggested by Tc-99 m pyrophosphate scintigraphy.
    Ikeda J, Katoh N, Sekijima Y, Ikeda S
    Amyloid, 22(4), 257-258, 2015
  • Spinal Intradural Extramedullary Cavernous Angioma Presenting with Superficial Siderosis and Hydrocephalus: A Case Report and Review of the Literature
    Katoh N, Yoshida T, Uehara T, Ito K, Hongo K, Ikeda S
    Intern Med, 53(16), 1863-7, 2014
  • Katoh N, Matsushima A, Kurozumi M, Matsuda M, Ikeda S: Marked and Rapid Regression of Hepatic Amyloid Deposition in a Patient with Systemic Light Chain (AL) Amyloidosis after High-dose Melphalan Therapy with Stem Cell Transplantation
    Katoh N, Matsushima A, Kurozumi M, Matsuda M, Ikeda S
    Intern Med, 53(17), 1991-5, 2014
  • Motor branch biopsy of the pronator teres muscle in a patient with painful forearm neuropathy
    Kinoshita T, Fukushima K, Abe RT, Ogawa Y, Nakagawa M, Katoh N, Yoshida T, Kato H, Ikeda S
    Case Rep Neurol, 6(2), 202-6, 2014
  • Waldenström's macroglobulinemia accompanying systemic amyloidosis: the usefulness of endobronchial ultrasound-guided transbronchial needle aspiration for detecting amyloid deposits
    Ishiguro T, Takayanagi N, Katoh N, Shimizu Y, Hoshi T, Yanagisawa T, Sugita Y
    Intern Med, 53(24), 2789-93, 2014
  • Clinical manifestations at diagnosis in Japanese patients with systemic Al amyloidosis: a retrospective study of 202 cases with a special attention to uncommon symptoms.
    Matsuda M, Katoh N, Ikeda S
    Intern Med, 53(5), 403-12, 2014
  • Thermal stability threshold for amyloid formation in light chain amyloidosis
    Poshusta TL, Katoh N, Gertz MA, Dispenzieri A, Ramirez-Alvarado M
    Int J Mol Sci, 14(11), 22604-22617, 15 Nov. 2013
  • A reappraisal of immunoglobulin variable gene primers and its impact on assessing clonal relationships between PB B cells and BM plasma cells in AL amyloidosis.
    Katoh N, Poshusta TL, Manske MK, Dispenzieri A, Gertz MA, Abraham RS, Ramirez-Alvarado M.
    J Clin Immunol, 31(6), 1029-1037, 01 Dec. 2011
  • Surgical removal of amyloid-laden lymph nodes: a possible therapeutic approach in a primary systemic AL amyloidosis patient with focal lymphadenopathy.
    Matsuda M, Katoh N, Tazawa K, Shimojima Y, Mishima Y, Sano K, Ikeda S.
    Amyloid, 18(2), 79-82, 01 Jun. 2011WebofScienceリポジトリ電子ジャーナル
  • Regression of gastroduodenal amyloid deposition in systemic AL amyloidosis after intensive chemotherapies.
    Katoh N, Matsuda M, Tsuchiya-Suzuki A, Ikeda S.
    Br J Haematol, 153(4), 535-538, 01 May 2011
  • Peripheral nerve involvement in primary systemic AL amyloidosis: a clinical and electrophysiological study
    Matsuda, M.; Gono, T.; Morita, H.; Katoh, N.; Kodaira, M.; Ikeda, S.
    EUROPEAN JOURNAL OF NEUROLOGY, 18(4), 604-610, Apr. 2011WebofScienceリポジトリ電子ジャーナル
  • Takayasu's Arteritis in a Patient with Crohn's Disease: An Unexpected Association during Infliximab Therapy
    Katoh, Nagaaki; Kubota, Mayu; Shimojima, Yasuhiro; Ishii, Wataru; Matsuda, Masayuki; Akamatsu, Taiji; Ikeda, Shu-ichi
    INTERNAL MEDICINE, 49(2), 179-182, 2010WebofScienceリポジトリ電子ジャーナル
  • Successful Treatment with Rituximab in a Patient with Stiff-Person Syndrome Complicated by Dysthyroid Ophthalmopathy
    Katoh, Nagaaki; Matsuda, Masayuki; Ishii, Wataru; Morita, Hiroshi; Ikeda, Shu-ichi
    INTERNAL MEDICINE, 49(3), 237-241, 2010WebofScienceリポジトリ電子ジャーナル
  • Rituximab therapy in nephrotic syndrome due to AH amyloidosis
    Katoh, Nagaaki; Matsuda, Masayuki; Miyazaki, Daigo; Gono, Takahisa; Yazaki, Masahide; Ikeda, Shu-Ichi
    AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 16(3), 178-180, Jan. 2009WebofScienceリポジトリ電子ジャーナル
  • Marked shrinkage of amyloid lymphadenopathy after an intensive chemotherapy in a patient with IgM-associated AL amyloidosis
    Tazawa, Ko-Ichi; Katoh, Nagaaki; Shimojima, Yasuhiro; Matsuda, Masayuki; Ikeda, Shu-Ichi
    AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 16(3), 183-185, Jan. 2009WebofScienceリポジトリ電子ジャーナル
  • Absolute quantitative analysis of cardiac amyloidosis using SPECT/CT with 99mTc-pyrophosphate.
    Yanagisawa S, Takahashi Y, Sasaki J, Takasone K, Yoshie K, Koyama J, Katoh N, Yazaki M, Kuwahara K, Fujinaga Y, Sekijima Y.
    Amyloid, 28(3), 213-214

Affiliated academic society

  • 日本血液学会
  • The Japanese Society of Internal Medicine
  • Japan College of Rheumatology
  • Japan Amyloidosis Research Society