医学博士, 信州大学

血液学

Relationship between allergic transfusion reactions and allergic predisposition among pediatric patients with hematological/oncological disease
Yanagisawa, Ryu; Ishimine, Nau; Komori, Kazutoshi; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Sakashita, Kazuo; Tozuka, Minoru; Nakazawa, Yozo;
TRANSFUSION, 62(5), 1035-1044, 2022年05月

Investigation of patient factors associated with the number of transfusions required during chemotherapy for high-risk neuroblastoma
Konno, Saori; Yanagisawa, Ryu; Kubota, Noriko; Ogiso, Yoshifumi; Nishimura, Noriyuki; Sakashita, Kazuo; Tozuka, Minoru;
VOX SANGUINIS, 117(1), 71-79, 2022年01月

Relationship between allergic sensitisation-associated single-nucleotide polymorphisms and allergic transfusion reactions and febrile non-haemolytic transfusion reactions in paediatric cases
Ide, Yuichiro; Yanagisawa, Ryu; Kobayashi, Jun; Komori, Kazutoshi; Matsuda, Kazuyuki; Amano, Yuji; Nakazawa, Yozo; Takeshita, Toshikazu; Sakashita, Kazuo; Tozuka, Minoru;
Blood Transfusion, 20(2), 94-102, 2022年

HLA適合血小板の使用ガイド
日本輸血・細胞治療学会　製剤委員会　血小板小委員会;藤原 孝記;李 悦子;石田 明;米村 雄士;長井 一浩;冨山 佳昭;松﨑 浩史;井関 徹;秋野 光明;柳沢 龍;加藤 栄史;羽藤 高明
日本輸血細胞治療学会誌, 67(6), 573-588, 2021年12月24日

Analysis of Predictive Factors of Allergic Transfusion Reaction using Allergic Disposition in Pediatric Patients with Hematological/Oncological Disease
Yanagisawa, Ryu; Ishimine, Nau; Komori, Kazutoshi; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Sakashita, Kazuo; Tozuka, Minoru; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 68, 2021年11月

A Retrospective Survey of the Discontinuation Cases of JPSLG HLH-2004 Clinical Trial
Ono, Rintaro; Sakamoto, Kenichi; Doi, Takehiko; Yanagisawa, Ryu; Hashimoto, Hiroya; Tamura, Akihiro; Shioda, Yoko; Ishii, Eiichi; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 68, 2021年11月

A Phase I/II Clinical Trial of Piggybac-Modified GMR CAR-T Cell Therapy for CD116 Positive Relapsed/Refractory Myeloid Malignancies
Saito, Shoji; Tanaka, Miyuki; Morokawa, Hirokazu; Hirabayashi, Koichi; Inada, Yoichi; Usami, Yoko; Kojima, Shunsuke; Yanagisawa, Ryu; Nakazawa, Hideyuki; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 68, 2021年11月

洗浄血小板の使用ガイド　第6版（2021年改訂）
日本輸血・細胞治療学会　製剤委員会　血小板小委員会;秋野 光明;柳沢 龍;加藤 栄史;井関 徹;石田 明;冨山 佳昭;長井 一浩;藤原 孝記;松﨑 浩史;米村 雄士;李 悦子;羽藤 高明
日本輸血細胞治療学会誌, 67(4), 509-515, 2021年08月25日

Investigation of risk factors associated with erythrocyte engraftment after ABO-incompatible hematopoietic stem cell transplantation
Yanagisawa, Ryu; Nakazawa, Hideyuki; Nishina, Sayaka; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Nakazawa, Yozo;
CLINICAL TRANSPLANTATION, 35(6), e14300, 2021年06月

医療機関内において実施されるCAR-T細胞療法の概略について
柳沢 龍;山中 万次郎;中沢 洋三
信州医学雑誌, 69(1), 57-59, 2021年02月10日

Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
Shigemura, Tomonari; Sakashita, Kazuo; Okura, Eri; Morita, Daisuke; Komori, Kazutoshi; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 111(5), 702-710, 2020年05月

Prophylactic piperacillin administration in pediatric patients with solid tumors following different intensities of chemotherapy
Saito, Shoji; Yanagisawa, Ryu; Minami, Kisei; Uchida, Eriko; Watanabe, Tatsuo; Komori, Kazutoshi; Kurata, Takashi; Nakamura, Tomohiko; Sakashita, Kazuo;
PEDIATRICS INTERNATIONAL, 62(2), 158-168, 2020年02月

Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia
Saito, Shoji; Taira, Chiaki; Matsuda, Kazuyuki; Yanagisawa, Ryu; Morita, Daisuke; Shigemura, Tomonari; Yoshikawa, Kentaro; Tanaka, Miyuki; Sakashita, Kazuo; Mukai, Saki; Shimodaira, Shigetaka; Koike, Kenichi; Nakazawa, Yozo;
LEUKEMIA & LYMPHOMA, 61(4), 967-970, 2020年

Acquired dysfibrinogenemia: monoclonal lambda-type IgA binding to fibrinogen caused lower functional plasma fibrinogen level and abnormal clot formation
Arai, Shinpei; Kamijo, Tomu; Takezawa, Yuka; Sugano, Mitsutoshi; Nakazawa, Hideyuki; Yanagisawa, Ryu; Uehara, Takeshi; Honda, Takayuki; Okumura, Nobuo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2020年

Predictive Factors of Leukemia in Patients With Transient Abnormal Myelopoiesis: JCCG JPLSG TAM-10 Study
Yamato, Genki; Muramatsu, Hideki; Watanabe, Tomoyuki; Deguchi, Takao; Iwamoto, Shotaro; Hasegawa, Daisuke; Terui, Kiminori; Ueda, Takahiro; Yokosuka, Tomoko; Tanaka, Shiro; Yanagisawa, Ryu; Koh, Katsuyoshi; Saito, Akiko; Horibe, Keizo; Hayashi, Yasuhide; Adachi, Souichi; Mizutani, Shuki; Taga, Takashi; Ito, Etsuro; Watanabe, Kenichiro;
PEDIATRIC BLOOD & CANCER, 66, S36-S36, 2019年12月

Analysis of the clinical characteristics of pediatric patients who experience ifosfamide-induced encephalopathy
Ide, Yuichiro; Yanagisawa, Ryu; Kubota, Noriko; Sakashita, Kazuo; Tozuka, Minoru; Nakamura, Tomohiko; Honda, Takayuki;
PEDIATRIC BLOOD & CANCER, 66(12), 2019年12月

Analysis of clinical presentations of allergic transfusion reactions and febrile non-haemolytic transfusion reactions in paediatric patients
Yanagisawa, Ryu; Tatsuzawa, Yuka; Ono, Takako; Kohayashi, Jun; Tokutake, Yumi; Hidaka, Eiko; Sakashita, Kazuo; Nakamura, Tomohiko;
VOX SANGUINIS, 114(8), 826-834, 2019年11月

Investigation of factors associated with allergic transfusion reaction due to platelet transfusion and the efficacy of platelets resuspended in BRS-A in adult patients
Yamanaka, Manjiro; Yanagisawa, Ryu; Kojima, Shunsuke; Nakazawa, Hideyuki; Shimodaira, Shigetaka;
TRANSFUSION, 59(11), 3405-3412, 2019年11月

In Vivo Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Increases the Immune Effectiveness of Dendritic Cell-Based Cancer Vaccination
Shimodaira, Shigetaka; Yanagisawa, Ryu; Koya, Terutsugu; Hirabayashi, Koichi; Higuchi, Yumiko; Sakamoto, Takuya; Togi, Misa; Kato, Tomohisa, Jr.; Kobayashi, Takashi; Koizumi, Tomonobu; Koido, Shigeo; Sugiyama, Haruo;
VACCINES, 7(3), 2019年09月

Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol (vol 109, pg 612, 2019)
Yanagisawa, Ryu; Matsuda, Kazuyuki; Ohga, Shouichi; Kanegane, Hirokazu; Morimoto, Akira; Okamoto, Yasuhiro; Ohara, Akira; Fukushima, Keitaro; Sotomatsu, Manabu; Nomura, Keiko; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; Nakazawa, Yozo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 109(5), 629-629, 2019年05月

Factors predicting the recurrence of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children after treatment using the HLH-2004 protocol (vol 109, pg 612, 2019)
Yanagisawa, Ryu; Matsuda, Kazuyuki; Ohga, Shouichi; Kanegane, Hirokazu; Morimoto, Akira; Okamoto, Yasuhiro; Ohara, Akira; Fukushima, Keitaro; Sotomatsu, Manabu; Nomura, Keiko; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; Nakazawa, Yozo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 109(5), 629-629, 2019年05月

Comparison of administration of platelet concentrates suspended in M-sol or BRS-A for pediatric patients
Kojima, Shunsuke; Yanagisawa, Ryu; Tanaka, Miyuki; Nakazawa, Yozo; Shimodaira, Shigetaka;
TRANSFUSION, 58(12), 2952-2958, 2018年12月

Analysis of Prophylactic Antibiotic Administration During Chemotherapy in Pediatric Brain Tumors
Yanagisawa, Ryu; Saito, Shoji; Minami, Kisei; Uchida, Eriko; Watanabe, Tatsuo; Komori, Kazutoshi; Kurata, Takashi; Sakashita, Kazuo;
PEDIATRIC BLOOD & CANCER, 65, S102-S103, 2018年11月

Cisplatin-induced nephrotoxicity in patients with advanced neuroblastoma
Yanagisawa, Ryu; Kubota, Noriko; Hidaka, Eiko; Sakashita, Kazuo; Tanaka, Miyuki; Nakazawa, Yozo; Nakamura, Tomohiko;
PEDIATRIC BLOOD & CANCER, 65(9), 2018年09月

PiggyBac Transposon-Mediated CAR-T Cells Targeting GM-CSF Receptors Prolong the Survival of Mice Bearing Human Acute Myeloid Leukemia
Hasegawa, Aiko; Narimatsu, Shogo; Tanaka, Miyuki; Nagai, Mika; Morita, Daisuke; Saito, Shoji; Nakano, Shigeru; Onozato, Tomoya; Hayashi, Morimichi; Matsuda, Kazuyuki; Yanagisawa, Ryu; Ohnota, Hideki; Nakazawa, Yozo;
MOLECULAR THERAPY, 26(5), 194-195, 2018年05月

PiggyBac Transposon-Mediated CAR-T Cells Targeting GM-CSF Receptors Prolong the Survival of Mice Bearing Human Acute Myeloid Leukemia
Hasegawa, Aiko; Narimatsu, Shogo; Tanaka, Miyuki; Nagai, Mika; Morita, Daisuke; Saito, Shoji; Nakano, Shigeru; Onozato, Tomoya; Hayashi, Morimichi; Matsuda, Kazuyuki; Yanagisawa, Ryu; Ohnota, Hideki; Nakazawa, Yozo;
MOLECULAR THERAPY, 26(5), 194-195, 2018年05月

WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study
Yanagisawa, Ryu; Koizumi, Tomonobu; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Nagai, Kazuhiro; Kobayashi, Masanori; Okamoto, Masato; Sugiyama, Haruo; Shimodaira, Shigetaka;
ANTICANCER RESEARCH, 38(4), 2217-2225, 2018年04月

Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
ANTICANCER RESEARCH, 38(4), 2227-2234, 2018年04月

WT1-pulsed Dendritic Cell Vaccine Combined with Chemotherapy for Resected Pancreatic Cancer in a Phase I Study
Yanagisawa, Ryu; Koizumi, Tomonobu; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Nagai, Kazuhiro; Kobayashi, Masanori; Okamoto, Masato; Sugiyama, Haruo; Shimodaira, Shigetaka;
ANTICANCER RESEARCH, 38(4), 2217-2225, 2018年04月

Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
ANTICANCER RESEARCH, 38(4), 2227-2234, 2018年04月

Neuroblastoma invading the kidney through the renal hilum
Yanagisawa, Ryu; Ogiso, Yoshifumi; Furukawa, Tomoko;
CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(1), 196-198, 2018年02月

Neuroblastoma invading the kidney through the renal hilum
Yanagisawa, Ryu; Ogiso, Yoshifumi; Furukawa, Tomoko;
CLINICAL AND EXPERIMENTAL NEPHROLOGY, 22(1), 196-198, 2018年02月

Outcome of Children with Hemophagocytic Lymphohistiocytosis with HLH-2004 Protocol in Japan
Yanagisawa, Ryu; Nakazawa, Yozo; Matsuda, Kazuyuki; Yasumi, Takahiro; Kanegane, Hirokazu; Ohga, Shouichi; Morimoto, Akira; Saito, Akiko M.; Horibe, Keizo; Ishii, Eiichi; HLH LCH Comm Members Japan;
PEDIATRIC BLOOD & CANCER, 64, S42-S43, 2017年11月

Hypoglycemia During the Temporary Interruption of Parenteral Nutrition Infusion in Pediatric Hematopoietic Stem Cell Transplantation
Yanagisawa, Ryu; Takeuchi, Kouichi; Komori, Kazutoshi; Fujihara, Ikuko; Hidaka, Yoshihiko; Morita, Daisuke; Futatsugi, Akiko; Ono, Takako; Hidaka, Eiko; Sakashita, Kazuo; Shiohara, Masaaki;
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, 41(8), 1414-1418, 2017年11月

Transfusion-associated hypoxemia in pediatric patients with solid tumors after autologous peripheral blood stem cell transplantation
Yanagisawa, Ryu; Abe, Seiki; Fujihara, Ikuko; Komori, Kazutoshi; Kondo, Yoshiaki; Sakashita, Kazuo; Nakamura, Tomohiko;
TRANSFUSION AND APHERESIS SCIENCE, 56(5), 744-747, 2017年10月

Myelomonocytic differentiation associated with NPM1-RARA rearrangement
Yanagisawa, Ryu; Ogiso, Yoshifumi; Yoshikawa, Kentaro; Tanaka, Miyuki; Matsuda, Kazuyuki; Ishii, Eizaburo;
BRITISH JOURNAL OF HAEMATOLOGY, 179(2), 183-183, 2017年10月

Asymptomatic subcutaneous cervical mass due to Actinomyces odontolyticus infection in a pyriform sinus fistula
Yanagisawa, Ryu; Minami, Kisei; Kubota, Noriko; Iwade, Tamaki; Ogiso, Yoshifumi;
PEDIATRICS INTERNATIONAL, 59(8), 941-942, 2017年08月

Ocular and nasal symptoms prior to acute skin graft-versus-host disease
Fujihara, Ikuko; Yanagisawa, Ryu; Sato, Ririko; Kitazawa, Noritaka; Sakashita, Kazuo;
PEDIATRICS INTERNATIONAL, 59(7), 833-834, 2017年07月

Transfusion-associated circulatory overload in a pediatric patient with neuroblastoma
Yanagisawa, Ryu; Fujihara, Ikuko; Komori, Kazutoshi; Abe, Seiki; Ono, Takako; Sakashita, Kazuo; Nakamura, Tomohiko;
TRANSFUSION AND APHERESIS SCIENCE, 56(3), 445-447, 2017年06月

Interferon-alpha-inducible Dendritic Cells Matured with OK-432 Exhibit TRAIL and Fas Ligand Pathway-mediated Killer Activity
Koya, Terutsugu; Yanagisawa, Ryu; Higuchi, Yumiko; Sano, Kenji; Shimodaira, Shigetaka;
SCIENTIFIC REPORTS, 7, 2017年

Transfusion-related acute lung injury in an infant
Yanagisawa, Ryu; Takeuchi, Kouichi; Kurata, Takashi; Sakashita, Kazuo; Shimodaira, Shigetaka; Ishii, Eizaburo;
PEDIATRICS INTERNATIONAL, 58(6), 543-544, 2016年06月

Transient Deformation of Neutrophils in Kawasaki Disease
Koike, Yumi; Yanagisawa, Ryu; Ogiso, Yoshifumi; Cho, Yoshiaki; Minami, Kisei; Takeuchi, Kouichi; Sakashita, Kazuo; Higuchi, Tsukasa;
JOURNAL OF PEDIATRICS, 173, 238-+, 2016年06月

Failure to Thrive and Bilateral Periorbital Ecchymosis
Komori, Kazutoshi; Yanagisawa, Ryu; Fujihara, Ikuko; Kanai, Hiroaki; Sakashita, Kazuo;
JOURNAL OF PEDIATRICS, 172, 215-+, 2016年05月

Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction
Hirabayashi, Koichi; Kurata, Takashi; Horiuchi, Kazuki; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 63(4), 709-711, 2016年04月

Preoperative Treatment With Pazopanib in a Case of Chemotherapy-Resistant Infantile Fibrosarcoma
Yanagisawa, Ryu; Noguchi, Masahiko; Fujita, Kenya; Sakashita, Kazuo; Sano, Kenji; Ogiso, Yoshifumi; Katsuyama, Yoshihiko; Kondo, Yoshiaki; Komori, Kazutoshi; Fujihara, Ikuko; Kitamura, Rei; Hiroma, Takehiko; Nakamura, Tomohiko;
PEDIATRIC BLOOD & CANCER, 63(2), 348-351, 2016年02月

Temozolomide Treatment for Pediatric Refractory Anaplastic Ependymoma with Low MGMT Protein Expression
Komori, Kazutoshi; Yanagisawa, Ryu; Miyairi, Yosuke; Sakashita, Kazuo; Shiohara, Masaaki; Fujihara, Ikuko; Morita, Daisuke; Nakamura, Tomohiko; Ogiso, Yoshifumi; Sano, Kenji; Shirahata, Mitsuaki; Fukuoka, Kohei; Ichimura, Koichi; Shigeta, Hiroaki;
PEDIATRIC BLOOD & CANCER, 63(1), 152-155, 2016年01月

Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review
Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Saito, Shoji; Tanaka, Miyuki; Shiohara, Masaaki; Shimodaira, Shigetaka; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 103(1), 107-111, 2016年01月

小児同種骨髄移植後possible TRALI
柳沢 龍;村田 マサ子;坂下 一夫;下平 滋隆;石井 栄三郎
日本輸血細胞治療学会誌, 62(3), 439-440, 2016年

Factors related to allergic transfusion reactions and febrile non-haemolytic transfusion reactions in children.
Yanagisawa R, Shimodaira S, Sakashita K, et al.
Vox Sang., 110(4), 376-84, 2016年

Wilms tumor accompanied by premature chromatid separation.
Shimada K, Yanagisawa R, Kubota N, et al.
Pediatr Blood Cancer., 2016年

Hypoglycemia During the Temporary Interruption of Parenteral Nutrition Infusion in Pediatric Hematopoietic Stem Cell Transplantation.
Yanagisawa R, Takeuchi K, Komori K, et al.
JPEN J Parenter Enteral Nutr., 2016年

Multinucleated giant cells in Langerhans cell histiocytosis.
Yanagisawa R, Ogiso Y, Miyairi Y, et al.
Br J Haematol., 174(1), 7, 2016年

Thrombocytosis in a newborn with Down syndrome and transient abnormal myelopoiesis.
Fujihara I, Yanagisawa R, Fukushima Y, et al.
Br J Haematol., 172(3), 314, 2016年

Deformation of erythroblasts in transient erythroblastopenia of childhood caused by HHV-6
Ogawa, Akira; Yanagisawa, Ryu;
BLOOD, 127(22), 2776-2776, 2016年

Interleukin-8-producing primary cardiac undifferentiated sarcoma in a child with sustained fever
Yanagisawa, Ryu; Nakamura, Tomohiko; Ogiso, Yoshifumi; Hachiya, Akira; Fujihara, Ikuko; Morita, Daisuke; Sakashita, Kazuo; Kitamura, Masatomo; Matsui, Hikoro; Nishijima, Fumie; Hayashi, Hidetaka; Hidaka, Eiko; Sano, Kenji; Shiohara, Masaaki; Yasukochi, Satoshi;
PEDIATRICS INTERNATIONAL, 57(4), 742-745, 2015年08月

Pretransplant-corrected QT dispersion as a predictor of pericardial effusion after pediatric hematopoietic stem cell transplantation
Yanagisawa, Ryu; Ishii, Eizaburo; Motoki, Noriko; Yamazaki, Shoko; Morita, Daisuke; Sakashita, Kazuo; Shiohara, Masaaki; Tanaka, Miyuki; Hidaka, Yoshihiko; Kubota, Noriko; Hidaka, Eiko; Ogiso, Yoshifumi; Nakamura, Tomohiko; Yasukochi, Satoshi;
TRANSPLANT INTERNATIONAL, 28(5), 565-574, 2015年05月

SIGNIFICANCE OF MOLECULAR MONITORING IN CHILDREN WITH EPSTEIN-BARR VIRUS-ASSOCIATED HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS
Yanagisawa, Ryu; Nakazawa, Yozo; Matsuda, Kazuyuki; Morimoto, Akira; Ishii, Eiichi; Japan Pediat Leukemia Lymphoma;
PEDIATRIC BLOOD & CANCER, 62, S17-S17, 2015年05月

Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature
Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;
CYTOTHERAPY, 17(3), 330-335, 2015年03月

Smoking influences the yield of dendritic cells for cancer immunotherapy
Shimodaira S, Higuchi Y, Koya T, Kobayashi T, Yanagisawa R, Hirabayashi K, Ito K, Koizumi T, Maejima S and Udagawa N
Pharmaceutical Regulatory Affairs, 4(1), 133, 2015年

Prospective Study of 168 Infants with Transient Abnormal Myelopoiesis with Down Syndrome: Japan Pediatric Leukemia/Lymphoma Study Group, TAM-10 Study
Muramatsu, Hideki; Watanabe, Tomoyuki; Hasegawa, Daisuke; Myoung-ja, Park; Iwamoto, Shotaro; Taga, Takashi; Ito, Etsuro; Toki, Tsutomu; Terui, Kiminori; Yanagisawa, Ryu; Koh, Katsuyoshi; Saito, Akiko M.; Horibe, Keizo; Hayashi, Yasuhide; Adachi, Souichi; Mizutani, Shuki; Watanabe, Kenichiro;
BLOOD, 126(23), 2015年

Storage of volume-reduced washed platelets in M-sol additive solution for 7 days
Hirayama, Junichi; Fujihara, Mitsuhiro; Akino, Mitsuaki; Kojima, Shunsuke; Yanagisawa, Ryu; Homma, Chihiro; Kato, Toshiaki; Ikeda, Hisami; Azuma, Hiroshi; Shimodaira, Shigetaka; Takamoto, Shigeru;
TRANSFUSION, 54(12), 3173-3177, 2014年12月

Anti-leukemic potency of piggyBac-mediated CD 19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
Saito, Shoji; Nakazawa, Yozo; Sueki, Akane; Matsuda, Kazuyuki; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Sato, Yuko; Okabe, Seiichi; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooney, Cliona M.; Koike, Kenichi;
CYTOTHERAPY, 16(9), 1257-1269, 2014年09月

Reversal of Tumor Immune Inhibition Using a Chimeric Cytokine Receptor
Leen, Ann M.; Sukumaran, Sujita; Watanabe, Norihiro; Mohammed, Somala; Keirnan, Jacqueline; Yanagisawa, Ryu; Anurathapan, Usanarat; Rendon, David; Heslop, Helen E.; Rooney, Cliona M.; Brenner, Malcolm K.; Vera, Juan F.;
MOLECULAR THERAPY, 22(6), 1211-1220, 2014年06月

Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies
Hirabayashi, Kanae; Nakazawa, Yozo; Matsuura, Hiroki; Hara, Yosuke; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 99(4), 477-486, 2014年04月

Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
Hirabayashi, Koichi; Nakazawa, Yozo; Sakashita, Kazuo; Kurata, Takashi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;
SCIENTIFIC REPORTS, 4, 2014年

Usefulness of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission for Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm With Skin Involvement: A Case Report and Review of Literature
Sakashita, Kazuo; Saito, Shoji; Yanagisawa, Ryu; Tanaka, Miyuki; Yoshikawa, Kentaro; Hirabayashi, Koichi; Tsukahara, Keiko; Motobayashi, Mitsuo; Nakazawa, Yozo; Koike, Kenichi;
PEDIATRIC BLOOD & CANCER, 60(11), E140-E142, 2013年11月

Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients
Yanagisawa, Ryu; Shimodaira, Shigetaka; Kojima, Shunsuke; Nakasone, Nobuhiko; Ishikawa, Shinsuke; Momose, Kayo; Honda, Takayuki; Yoshikawa, Kentaro; Saito, Shoji; Tanaka, Miyuki; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Akino, Mitsuaki; Hirayama, Junichi; Azuma, Hiroshi; Koike, Kenichi;
TRANSFUSION, 53(9), 2053-2060, 2013年09月

Cytomegalovirus Retinitis During Maintenance Therapy for T-Cell Acute Lymphoblastic Leukemia
Wakai, Kimiko; Sano, Hirozumi; Shimada, Akira; Shiozawa, Yusuke; Park, Myoung-ja; Sotomatsu, Manabu; Yanagisawa, Ryu; Koike, Kenichi; Kozawa, Kunihisa; Ryo, Akihide; Tsukagoshi, Hiroyuki; Kimura, Hirokazu; Hayashi, Yasuhide;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 35(2), 162-163, 2013年03月

Food allergy after cord blood transplantation in children
Sakashita, Kazuo; Nakazawa, Yozo; Yanagisawa, Ryu; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Hirabayashi, Koichi; Kusakari, Mai; Kato, Sawako; Hidaka, Nao; Nakayama, Yoshiko; Shigemura, Tomonari; Kobayashi, Norimoto; Kobayashi, Mikiko; Shiohara, Masaaki; Koike, Kenichi;
BRITISH JOURNAL OF HAEMATOLOGY, 158(5), 672-676, 2012年09月

Rapidly Generated Multivirus-specific Cytotoxic T Lymphocytes for the Prophylaxis and Treatment of Viral Infections
Gerdemann, Ulrike; Keirnan, Jacqueline M.; Katari, Usha L.; Yanagisawa, Ryu; Christin, Anne S.; Huye, Leslie E.; Perna, Serena K.; Ennamuri, Sravya; Gottschalk, Stephen; Brenner, Malcolm K.; Heslop, Helen E.; Rooney, Cliona M.; Leen, Ann M.;
MOLECULAR THERAPY, 20(8), 1622-1632, 2012年08月

CD19-Specific T-Cell Therapy for Refractory Philadelphia-Chromosome-Positive Acute Lymphoblastic Leukemia Using PiggyBac Transposon-Based Gene Modification and Low Autoserum-Containing, but Xeno-Free and Tumor Cell Line-Free Culture System
Saito, Shoji; Nakazawa, Yozo; Tanaka, Miyuki; Yanagisawa, Ryu; Maeda, Yasuhiro; Inukai, Takeshi; Sugita, Kanji; Wilson, Matthew H.; Rooeny, Cliona M.; Koike, Kenichi;
MOLECULAR THERAPY, 20, S184-S185, 2012年05月

Critical Illness Polyneuropathy and Myopathy Caused by Bacillus Cereus Sepsis in Acute Lymphoblastic Leukemia
Hirabayashi, Koichi; Shiohara, Masaaki; Suzuki, Takefumi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 34(3), E110-E113, 2012年04月

Telecommunication system for children undergoing stem cell transplantation
Higuchi, Kazumi; Nakazawa, Yozo; Sakata, Nobuhiro; Takizawa, Masaomi; Ohso, Keiko; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;
PEDIATRICS INTERNATIONAL, 53(6), 1002-1009, 2011年12月

Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia
Saito, Shoji; Matsuda, Kazuyuki; Taira, Chiaki; Sano, Kenji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;
LEUKEMIA RESEARCH, 35(12), 1578-1584, 2011年12月

Association of IRF5 Polymorphisms with Susceptibility to Hemophagocytic Lymphohistiocytosis in Children
Yanagimachi, Masakatsu; Goto, Hiroaki; Miyamae, Takako; Kadota, Keisuke; Imagawa, Tomoyuki; Mori, Masaaki; Sato, Hidenori; Yanagisawa, Ryu; Kaneko, Tetsuji; Morita, Satoshi; Ishii, Eiichi; Yokota, Shumpei;
JOURNAL OF CLINICAL IMMUNOLOGY, 31(6), 946-951, 2011年12月

置換液M-solを用いた置換血小板(R-PC)調製のプロセスバリデーションに関する検討
小嶋 俊介;柳沢 龍;石川 伸介;中曽根 允彦;中澤 希世子;長谷川 康久;小林 孝至;平山 順一;秋野 光明;東 寛;下平 滋隆
日本輸血細胞治療学会誌 = Japanese journal of transfusion and cell therapy, 57(5), 379-385, 2011年09月25日

Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome
Hirabayashi, Koichi; Shiohara, Masaaki; Takahashi, Daijiro; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Nakamura, Tomohiko; Ishii, Eizaburo; Koike, Kenichi;
LEUKEMIA & LYMPHOMA, 52(8), 1523-1527, 2011年08月

WT1 AND MUC1-PULSED DENDRITIC CELL VACCINATION THERAPY FOR NON-SMALL-CELL LUNG CANCER
Kobayashi, Takashi; Koizumi, Tomonobu; Tateishi, Kazunari; Urushihata, Kazuhisa; Yamamoto, Hiroshi; Hanaoka, Masayuki; Kubo, Keishi; Shimodaira, Shigetaka; Yanagisawa, Ryu; Muramatsu, Saori; Higuchi, Yumiko; Goto, Takahumi; Ishikawa, Shinsuke;
JOURNAL OF THORACIC ONCOLOGY, 6(6), S1266-S1267, 2011年06月

小児慢性特定疾患治療研究事業における「血小板の異常をきたす疾患」の登録状況
草刈 麻衣; 塩原 正明; 齋藤 章治; 田中 美幸; 柳沢 龍; 坂下 一夫; 加藤 忠明; 藤本 純一郎; 小池 健一;
日本小児血液学会雑誌, 25(2), 74-80, 2011年04月30日

Disappearance of Minimal Residual Disease After the Early Withdrawal of Immunosuppressants in a Patient With Juvenile Myelomonocytic Leukemia
Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Nakazawa, Yozo; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;
PEDIATRIC BLOOD & CANCER, 56(3), 501-502, 2011年03月

Detection of T-cell receptor gene rearrangement in children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis using the BIOMED-2 multiplex polymerase chain reaction combined with GeneScan analysis
Matsuda, Kazuyuki; Nakazawa, Yozo; Yanagisawa, Ryu; Honda, Takayuki; Ishii, Eiichi; Koike, Kenichi;
CLINICA CHIMICA ACTA, 412(17-18), 1554-1558, 2011年

Increased pretransplant QT dispersion as a risk factor for the development of cardiac complications during and after preparative conditioning for pediatric allogeneic hematopoietic stem cell transplantation
Motoki, Noriko; Shimizu, Takashi; Akazawa, Yohei; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Motoki, Hirohiko; Nakazawa, Yozo; Sakashita, Kazuo; Iwasaki, Yasushi; Shiohara, Masaaki; Koike, Kenichi;
PEDIATRIC TRANSPLANTATION, 14(8), 986-992, 2010年12月

Mutations in the ribosomal protein genes in Japanese patients with Diamond-Blackfan anemia
Konno, Yuki; Toki, Tsutomu; Tandai, Satoru; Xu, Gang; Wang, RuNan; Terui, Kiminori; Ohga, Shouichi; Hara, Toshiro; Hama, Asahito; Kojima, Seiji; Hasegawa, Daiichiro; Kosaka, Yoshiyuki; Yanagisawa, Ryu; Koike, Kenichi; Kanai, Rie; Imai, Tsuyoshi; Hongo, Teruaki; Park, Myoung-Ja; Sugita, Kanji; Ito, Etsuro;
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 95(8), 1293-1299, 2010年08月

HDM2 impairs Noxa transcription and affects apoptotic cell death in a p53/p73-dependent manner in neuroblastoma
Shi, Yun; Takenobu, Hisanori; Kurata, Kenji; Yamaguchi, Yohko; Yanagisawa, Ryu; Ohira, Miki; Koike, Kenichi; Nakagawara, Akira; Jiang, Ling Ling; Kamijo, Takehiko;
EUROPEAN JOURNAL OF CANCER, 46(12), 2324-2334, 2010年08月

Quantitative assessment of PTPN11 or RAS mutations at the neonatal period and during the clinical course in patients with juvenile myelomonocytic leukaemia
Matsuda, Kazuyuki; Sakashita, Kazuo; Taira, Chiaki; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Shiohara, Masaaki; Kanegane, Hirokazu; Hasegawa, Daiichiro; Kawasaki, Keiichiro; Endo, Mikiya; Yajima, Shuhei; Sasaki, Shinya; Kato, Keisuke; Koike, Kazutoshi; Kikuchi, Akira; Ogawa, Atsushi; Watanabe, Akihiro; Sotomatsu, Manabu; Nonoyama, Shigeaki; Koike, Kenichi;
BRITISH JOURNAL OF HAEMATOLOGY, 148(4), 593-599, 2010年02月

Polymyxin-Direct Hemoperfusion for Sepsis-Induced Multiple Organ Failure
Hirabayashi, Koichi; Shiohara, Masaaki; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;
PEDIATRIC BLOOD & CANCER, 55(1), 202-205, 2010年

Clinical Significance of Cloned Expansion and CD5 Down-Regulation in Epstein-Barr Virus (EBV)-Infected CD8(+) T Lymphocytes in EBV-Associated Hemophagocytic Lymphohistiocytosis
Toga, Akiko; Wada, Taizo; Sakakibara, Yasuhisa; Mase, Shintaro; Araki, Raita; Tone, Yumi; Toma, Tomoko; Kurokawa, Toshiro; Yanagisawa, Ryu; Tamura, Kentaro; Nishida, Naonori; Taneichi, Hiromichi; Kanegane, Hirokazu; Yachie, Akihiro;
JOURNAL OF INFECTIOUS DISEASES, 201(12), 1923-1932, 2010年

Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations
Matsuda, Kazuyuki; Taira, Chiaki; Sakashita, Kazuo; Saito, Shoji; Tanaka-Yanagisawa, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Fukushima, Keitaro; Oda, Megumi; Honda, Takayuki; Nakahata, Tatsutoshi; Koike, Kenichi;
BLOOD, 115(26), 5429-5431, 2010年

Epstein-Barr ウイルス関連血球貪食性リンパ組織球症2例における免疫学的・ウイルス学的解析
田村 賢太郎; 金兼 弘和; 西田 直徳; 榊 久乃; 野村 恵子; 柳沢 龍; 和田 泰三; 谷内江 昭宏; 宮脇 利男;
日本小児血液学会雑誌, 23(5), 360-365, 2009年12月31日

亜鉛投与が契機となり銅欠乏性の好中球減少・貧血をきたした重症心身障害の女児例
永春 幸子;塩原 正明;齋藤 章治;田中 美幸;柳沢 龍;坂下 一元;稲葉 雄二;小池 健一
日本小児血液学会雑誌, 23(5), 355-359, 2009年12月31日

Low toxicity of a conditioning with 8-Gy total body irradiation, fludarabine and cyclophosphamide as preparative regimen for allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies
Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Tanaka, Miyuki; Shikama, Naoto; Kamijo, Takehiko; Shiohara, Masaaki; Koike, Kenichi;
PEDIATRIC TRANSPLANTATION, 13(6), 737-745, 2009年09月

Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation
Nakazawa, Yozo; Suzuki, Takefumi; Fukuyama, Tetsuhiro; Katsuyama, Yoshihiko; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Shiohara, Masaaki; Koike, Kenichi;
PEDIATRIC TRANSPLANTATION, 13(5), 632-635, 2009年08月

Ela2 Mutations and Clinical Manifestations in Familial Congenital Neutropenia
Shiohara, Masaaki; Shigemura, Tomonari; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Asada, Hiroshi; Ishii, Eizaburo; Koike, Kazutoshi; Chin, Motoaki; Kobayashi, Masao; Koike, Kenichi;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 31(5), 319-324, 2009年05月

Cryptic insertion into 11q23 of MLLT10 not involved in t(1;15;11;10)(p36;q11;q23;q24) in infant acute biphenotypic leukemia
Matsuda, Kazuyuki; Tanaka, Miyuki; Araki, Sachiko; Yanagisawa, Ryu; Yamauchi, Kazuyoshi; Koike, Kenichi;
CANCER GENETICS AND CYTOGENETICS, 190(2), 113-120, 2009年

Mutations in Ribosomal Protein Genes of Diamond-Blackfan Anemia Patients in Japan
Konno, Yuki; Toki, Tsutomu; Tandai, Satoru; Xu, Gang; Terui, Kiminori; Ohga, Shouichi; Kojima, Seiji; Yanagisawa, Ryu; Koike, Kenichi; Hasegawa, Daiichiro; Kosaka, Yoshiyuki; Kanei, Rie; Imai, Tsuyoshi; Hongo, Teruaki; Park, Myoung-Ja; Watanabe, Arata; Ito, Etsuro;
BLOOD, 114(22), 1241-1242, 2009年

A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood progenitor cell transplantation from the mother in a patient with relapsed leukemia
Nakazawa, Yozo; Saito, Satoshi; Hasegawa, Yasuhisa; Yanagisawa, Ryu; Sakashita, Kazuo; Kamijo, Takehiko; Miyazaki, Toru; Sato, Shinichiro; Ikeda, Hisami; Ikebuchi, Kenji; Koike, Kenichi;
TRANSFUSION, 47(2), 326-334, 2007年02月

A complex karyotype, including a three-way translocation generating a NUP98-HOXD13 transcript, in an infant with acute myeloid leukemia
Hidaka, Eiko; Tanaka, Miyuki; Matsuda, Kazuyuki; Ishikawa-Matsumura, Masayo; Yamauchi, Kazuyoshi; Sano, Kenji; Honda, Takayuki; Wakui, Keiko; Yanagisawa, Ryu; Nakazawa, Yozo; Sakashita, Kazuo; Shiohara, Masaaki; Ishii, Eizaburo; Koike, Kenichi;
CANCER GENETICS AND CYTOGENETICS, 176(2), 137-143, 2007年

Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations
Matsuda, Kazuyuki; Shimada, Akira; Yoshida, Nao; Ogawa, Atsushi; Watanabe, Akihiro; Yajima, Shuhei; Iizuka, Susumu; Koike, Kazutoshi; Yanai, Fumio; Kawasaki, Keiichiro; Yanagimachi, Masakatsu; Kikuchi, Akira; Ohtsuka, Yoshitoshi; Hidaka, Eiko; Yamauchi, Kazuyoshi; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo; Shiohara, Masaaki; Manabe, Atsushi; Kojima, Seiji; Koike, Kenichi;
BLOOD, 109(12), 5477-5480, 2007年

アレルギー性輸血副反応発症機序の全貌解明を目指した患者因子ならびに製剤因子の解析
科学研究費補助金, 基盤研究(C)
2022年04月01日 - 2025年03月31日

ネオアンチゲンから展開する膵臓癌に対する複合的免疫療法の開発
科学研究費補助金, 基盤研究(C)
2019年04月01日 - 2023年03月31日

小児脳腫瘍特異的細胞傷害性T細胞にキメラ抗原受容体を応用した新規治療戦略の確立
科学研究費補助金, 基盤研究(C)
2016年04月01日 - 2019年03月31日

難治性小児急性骨髄性白血病に対するメソセリンを用いた新規細胞免疫療法の開発
科学研究費補助金, 若手研究(B)
2014年04月01日 - 2016年03月31日