岳 鳳鳴 (ガク ホウメイ)   

学術研究院(医学系)

医学部 医学科 組織発生学 

助教(学部内講師) 

学位

  • 医学博士, 河北医科大学
  • 医学博士, 信州大学

研究キーワード

    iPS細胞 疾患モデル, ガン幹細胞

研究分野

  • 幹細胞研究

学歴

  • 2002年 - 2006年, 信州大学医学部組織発生学講座

論文

  • Evaluating the Cytocompatibility of Lactic Acid-Extracted Barramundi Skin Collagen for Cell Culture Applications"
    信州医学雑誌, 2024年
  • 葉酸が骨形成分化に及ぼす影響の解明: iPS細胞モデル研究
    信州医学雑誌, 2024年
  • Pathophysiological Investigation of Skeletal Deformities of Musculocontractural Ehlers-Danlos Syndrome Using Induced Pluripotent Stem Cells
    Genes (Basel), 2023年
  • Lipocalin‑2 inhibits pancreatic cancer stemness via the AKT/c‑Jun pathway
    Hum Cell, 2022年
  • Generation of an induced pluripotent stem cell lines HMSCASTi001-A from peripheral blood mononuclear cells of a 35-year-old healthy male
    Stem Cell Res, 2022年
  • Generation of an induced pluripotent stem cell lines HMSCASTi002-A from peripheral blood mononuclear cells of a 38-year-old healthy female individual
    Stem Cell Res, 2022年
  • Generation of an induced pluripotent stem cell lines HMSCASTi002-A from peripheral blood mononuclear cells of a 38-year-old healthy female individual
    Xian Xian, Jingrui Liu, Jiamin Zhang, Peipei Hao, Yingtong Zhai, Jingke Cheng, Fengming Yue, Min Ma, Zhanchi Zhang, Feng Luan, Qian Ren
    2022年
  • Lipocalin‑2 inhibits pancreatic cancer stemness via the AKT/c‑Jun pathway
    Peipei Hao· Jiamin Zhang· Shu Fang· Miaomiao Jia· Xian Xian· Sinan Yan · Yunpeng Wang · Qian Ren · Fengming Yue · Huixian Cui
    2022年
    責任著者
  • Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro.
    Hao P, Yue F, Xian X, Ren Q, Cui H, Wang Y.
    Life Sci., 254, 2020年
  • Lipocalin2 promotes cell proliferation and migration in ovarian cancer through activation of the ERK/GSK3β/β-catenin signaling pathway
    Peipei Hao, Haili Li, Aiyuan Wu, Jiamin Zhang, Chang Wang, Xian Xian, Qian Ren, Nana Hao, Yunpeng Wang, Fengming Yue, Huixian Cui
    2020年
  • Inhibiting effect of MicroRNA-3619-5p/PSMD10 axis on liver cancer cell growth in vivo and in vitro
    Peipei Hao, Fengming Yue, Xian Xian, Qian Ren, Huixian Cui, Yunpeng Wang
    2020年
  • Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture.
    Hirashima K, Yue F, Kobayashi M3, Uchida Y, Nakamura S, Tomotsune D,4, Matsumoto K, Takizawa-Shirasawa S, Yokoyama T, Kanno H, Sasaki K
    Cell Tissue Res., 375(3), 697-707, 2019年03月
  • Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia.
    Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K.
    Br J Haematol, 187(2), 163-173, 2019年
  • Induced Pluripotent Stem Cells as a Model for Therapy Personalization of Pediatric Patients: Disease Modeling and Drug Adverse Effects Prevention.
    Genova E, Pelin M, Sasaki K, Yue F, Lanzi G, Masneri S, Ventura A, Stocco G, Decorti G
    Curr Med Chem., 25(24), 2826-2839, 2018年
  • Stimulation of Embryonic Environments Produced by the Effect of Estradiol on Induced Pluripotent Stem Cells.
    Sawako Sakai, Daihachiro Tomotsune, Kanji Hirashima, Sakiko Takizawa, Tadayuki Yokoyama, Fengming Yue, Rika Tani, Ken Matsumoto, Katsunori Sasaki.
    Regenerative Medicine, 7(1), 1-5, 2018年
  • Reprogramming of retinoblastoma cancer cells into cancer stem cells
    Yue, Fengming; Hirashima, Kanji; Tomotsune, Daihachiro; Takizawa-Shirasawa, Sakiko; Yokoyama, Tadayuki; Sasaki, Katsunori;
    Biochemical and biophysical research communications, 482(4), 549-555, 2017年WebofScience電子ジャーナル
  • Earlobe-like peritoneal appendage near the angle of His: a useful landmark for demarcating the lateral margin of the gastric cardia.
    Hirashima K, Yue F, Tomotsune D, Sasaki K.
    Anat Sci Int, in press, 2016年電子ジャーナル
  • Enrichment of Pluripotent Stem Cell-Derived Hepatocyte-Like Cells by Ammonia Treatment
    Tomotsune, Daihachiro; Hirashima, Kanji; Fujii, Masako; Yue, Fengming; Matsumoto, Ken; Takizawa-Shirasawa, Sakiko; Yokoyama, Tadayuki; Sasaki, Katsunori;
    PLOS ONE, 11(9), 2016年WebofScience電子ジャーナル
  • Patients' Induced Pluripotent Stem Cells to Model Drug Induced Adverse Events: A Role in Predicting Thiopurine Induced Pancreatitis?
    Stocco, Gabriele; Lanzi, Gaetana; Yue, Fengming; Giliani, Silvia; Sasaki, Katsunori; Tommasini, Alberto; Pelin, Marco; Martelossi, Stefano; Ventura, Alessandro; Decorti, Giuliana;
    CURRENT DRUG METABOLISM, 17(1), 91-98, 2016年WebofScience電子ジャーナル
  • Experimental splenosis in the liver and lung spread through the vasculature.
    Seguchi S, Yue F, Asanuma K, Sasaki K.
    Cell Tissue Res, 360(2), 287-96, 2015年05月電子ジャーナル
  • New model for cardiomyocyte sheet transplantation using a virus-cell fusion technique
    Takahashi, Yuto; Tomotsune, Daihachiro; Takizawa, Sakiko; Yue, Fengming; Nagai, Mika; Yokoyama, Tadayuki; Hirashima, Kanji; Sasaki, Katsunori;
    WORLD JOURNAL OF STEM CELLS, 7(5), 883-893, 2015年WebofScience電子ジャーナル
  • FGF7 and cell density are required for final differentiation of pancreatic amylase-positive cells from human ES cells
    Takizawa-Shirasawa, Sakiko; Yoshie, Susumu; Yue, Fengming; Mogi, Akimi; Yokoyama, Tadayuki; Tomotsune, Daihachiro; Sasaki, Katsunori;
    CELL AND TISSUE RESEARCH, 354(3), 751-759, 2013年12月WebofScience電子ジャーナル
  • Unique kinetics of Oct3/4 microlocalization following dissociation of human embryonic stem cell colonies
    Ichikawa, Hinako; Kanoh, Yoshiya; Shirasawa, Sakiko; Yokoyama, Tadayuki; Yue, Fengming; Tomotsune, Daihachiro; Sasaki, Katsunori;
    ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, 195(1), 50-56, 2013年WebofScience電子ジャーナル
  • Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells
    Ichikawa, Hinako; Nakata, Naohiro; Abo, Youichi; Shirasawa, Sakiko; Yokoyama, Tadayuki; Yoshie, Susumu; Yue, Fengming; Tomotsune, Daihachiro; Sasaki, Katsunori;
    Cryobiology, 64(1), 12-22, 2012年02月WebofScience電子ジャーナル
  • In Vitro Transdifferentiation of HepG2 Cells to Pancreatic-Like Cells by CCl4, D-Galactosamine, and ZnCl2
    Kanoh, Yoshiya; Tomotsune, Daihachiro; Shirasawa, Sakiko; Yoshie, Susumu; Ichikawa, Hinako; Yokoyama, Tadayuki; Mae, Shin-Ichi; Ito, Jun; Mizuguchi, Masahiro; Matsumoto, Ken; Yue, Fengming; Sasaki, Katsunori;
    PANCREAS, 40(8), 1245-1252, 2011年11月WebofScience電子ジャーナル
  • A Novel Stepwise Differentiation of Functional Pancreatic Exocrine Cells from Embryonic Stem Cells
    Shirasawa, Sakiko; Yoshie, Susumu; Yokoyama, Tadayuki; Tomotsune, Daihachiro; Yue, Fengming; Sasaki, Katsunori;
    STEM CELLS AND DEVELOPMENT, 20(6), 1071-1078, 2011年06月WebofScience電子ジャーナル
  • FREEZE-THAWING SINGLE HUMAN EMBRYONIC STEM CELLS INDUCE E-CADHERIN AND ACTIN FILAMENT NETWORK DISRUPTION VIA G13 SIGNALING
    Ichikawa, Hinako; Yoshie, Susumu; Shirasawa, Sakiko; Yokoyama, Tadayuki; Yue, Fengming; Tomotsune, Daihachiro; Sasaki, Katsunori;
    CRYOLETTERS, 32(6), 516-524, 2011年WebofScience
  • Pancreatic exocrine enzyme-producing cell differentiation via embryoid bodies from human embryonic stem cells
    Shirasawa, Sakiko; Yoshie, Susumu; Yue, Fengming; Ichikawa, Hinako; Yokoyama, Tadayuki; Nagai, Mika; Tomotsune, Daihachiro; Hirayama, Masao; Sasaki, Katsunori;
    Biochemical and biophysical research communications, 410(3), 608-613, 2011年WebofScience電子ジャーナル
  • Differentiation of primate ES cells into retinal cells induced by ES cell-derived pigmented cells
    Yue, Fengming; Johkura, Kohei; Shirasawa, Sakiko; Yokoyama, Tadayuki; Inoue, Yuji; Tomotsune, Daihachiro; Sasaki, Katsunori;
    Biochemical and biophysical research communications, 394(4), 877-883, 2010年WebofScience電子ジャーナル
  • Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells
    Mae, Shin-Ichi; Shirasawa, Sakiko; Yoshie, Susumu; Sato, Fumi; Kanoh, Yoshiya; Ichikawa, Hinako; Yokoyama, Tadayuki; Yue, Fengming; Tomotsune, Daihachiro; Sasaki, Katsunori;
    Biochemical and biophysical research communications, 393(4), 877-882, 2010年WebofScience電子ジャーナル
  • Bone marrow stromal cells as an inducer for cardiomyocyte differentiation from mouse embryonic stem cells
    Yue, Fengming; Johkura, Kohei; Tomotsune, Daihachiro; Shirasawa, Sakiko; Yokoyama, Tadayuki; Nagai, Mika; Sasaki, Katsunori;
    ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, 192(5), 314-321, 2010年WebofScience電子ジャーナル
  • Hepatocyte Differentiation from Human ES Cells using the Simple Embryoid Body Formation Method and the Staged-Additional Cocktail
    Sasaki, Katsunori; Ichikawa, Hinako; Takei, Shunsuke; No, Hee Sung; Tomotsune, Daihachiro; Kano, Yoshiya; Yokoyama, Tadayuki; Sirasawa, Sakiko; Mogi, Akimi; Yoshie, Susumu; Sakaki, Shujiro; Yamada, Satoshi; Matsumoto, Ken; Mizuguchi, Masahiro; Yue, Fengming; Tanaka, Yoshiki;
    THESCIENTIFICWORLDJOURNAL, 9, 884-890, 2009年WebofScience電子ジャーナル
  • Cryopreservation of mouse embryoid bodies
    Ichikawa, Hinako; No, Heesung; Takei, Shunsuke; Takashimizu, Itsukei; Yue Fengming; Cui, Li; Ogiwara, Naoko; Johkura, Kohei; Nishimoto, Yoshiteru; Sasaki, Katsunori;
    Cryobiology, 54(3), 290-293, 2007年06月WebofScience電子ジャーナル
  • Glucagon-like peptide-1 differentiation of primate embryonic stem cells into insulin-producing cells
    Yue, Fengming; Cui, Li; Johkura, Kohei; Ogiwara, Naoko; Sasaki, Katsunori;
    TISSUE ENGINEERING, 12(8), 2105-2116, 2006年08月WebofScience
  • Induction of midbrain dopaminergic neurons from primate embryonic stem cells by coculture with Sertoli cells
    Yue, Fengming; Cui, Li; Johkura, Kohei; Ogiwara, Naoko; Sasaki, Katsunori;
    Stem Cells, 24(7), 1695-1706, 2006年07月WebofScience電子ジャーナル

共同研究・競争的資金等の研究課題

  • 幹細胞から特異細胞の分化誘導
  • がん幹細胞について研究