下島 恭弘 (シモジマ ヤスヒロ)   

学術研究院(医学系)

医学部 医学科 内科学第三 

准教授 

研究者情報

学位

  • 博士(医学), 信州大学大学院

研究分野

  • 免疫学, 臨床免疫学
  • 膠原病、アレルギー内科学, 膠原病学
研究活動情報

論文

  • Immunopathological features of myopathy associated with small-to-medium-sized vessel vasculitis and differences from autoimmune myositis
    Nomura S, Shimojima Y, Ichikawa T, Miyazaki D, Uruha A, Kishida D, Sekijima Y.
    Clin Exp Rheumatol, 42, 786-794, 2024年
    責任著者電子ジャーナル
  • Immune-mediated necrotizing myopathy with concomitant development of Kikuchi–Fujimoto disease.
    Ichikawa T, Furukawa R, Shimojima Y, Hoshino Y, Kishida D, Sekijima Y.
    Int J Rheum Dis, 27, e14894, 2024年
    責任著者
  • Quantitative evaluation of the thickened dura mater impacting clinical signs in immune-mediated hypertrophic pachymeningitis
    Ikeda J, Shimojima Y, Yamada A, Sekijima Y.
    J Neuro Sci, 453, 120780, 2023年09月
    責任著者電子ジャーナル
  • Hypertrophic pachymeningitis in ANCA-associated vasculitis: Clinical and immunopathological features and insights.
    Shimojima Y, Sekijima Y.
    Autoimmun Rev, 22, 103338, 2023年
    筆頭著者, 責任著者電子ジャーナル
  • Testicular vasculitis in eosinophilic granulomatosis with polyangiitis: a case-based review.
    Ichikawa T, Shimojima Y, Nomura S, Kishida D, Shiozaki M, Tanimura J, Sekijima Y.
    Clin Rheumatol, 42, 293-299, 2023年
    責任著者電子ジャーナル
  • Features of BAFF and APRIL receptors on circulating B cells in antineutrophil cytoplasmic antibody-associated vasculitis.
    Shimojima Y, Kishida D, Ichikawa T, Takamatsu R, Nomura S, Sekijima Y.
    Clin Exp Immunol, 213, 125-137, 2023年
    筆頭著者, 責任著者電子ジャーナル
  • Hypertrophic pachymeningitis in polyarteritis nodosa: a case-based review
    Nomura, Shun; Shimojima, Yasuhiro; Kondo, Yasufumi; Kishida, Dai; Sekijima, Yoshiki;
    CLINICAL RHEUMATOLOGY, 41(2), 567-572, 2022年02月
    責任著者WebofScience電子ジャーナル
  • Hypertrophic pachymeningitis in ANCA-associated vasculitis: A cross-sectional and multi-institutional study in Japan (J-CANVAS).
    Shimojima Y, Kishida D, Ichikawa T, Kida T, Yajima N, Omura S, Nakagomi D, Abe Y, Kadoya M, Takizawa N, Nomura A, Kukida Y, Kondo N, Yamano Y, Yanagida T, Endo K, Hirata S, Matsui K, Takeuchi T, Ichinose K, Kato M, Yanai R, Matsuo Y, Nishioka R, Okazaki R, Takata T, Ito T, Moriyama M, Takatani A, Miyawaki Y, Ito-Ihara T, Kawaguchi T, Kawahito Y, Sekijima S.
    24, 179, 2022年
    筆頭著者, 責任著者電子ジャーナル
  • The impact of normal serum complement levels on the disease classification and clinical characteristics in systemic lupus erythematosus.
    Takamatsu R, Shimojima Y, Kishida D, Ichikawa T, Sekijima Y.
    Adv Rheumatol, 62, 49, 2022年
    責任著者電子ジャーナル
  • Circulating regulatory T cells in adult-onset Still's disease: Focusing on their plasticity and stability
    Shimojima, Yasuhiro; Ichikawa, Takanori; Kishida, Dai; Takamatsu, Ryota; Sekijima, Yoshiki;
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 206(2), 184-195, 2021年11月
    筆頭著者, 責任著者WebofScience電子ジャーナル
  • 聴力障害で発症した高安動脈炎:症例報告とその臨床背景
    野村 俊, 市川 貴規, 塚田 景大, 岸田 大, 近藤 恭史, 下島 恭弘, 関島 良樹
    信州医学雑誌, 69(5), 261-266, 2021年10月
    責任著者リポジトリ電子ジャーナル
  • The implication of interferon-gamma-producing immunocompetent cells for evaluating disease activity and severity in adult-onset Still's disease
    Ichikawa, Takanori; Shimojima, Yasuhiro; Kishida, Dai; Ueno, Ken-ichi; Sekijima, Yoshiki;
    INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 24(9), 1176-1185, 2021年09月
    責任著者WebofScience電子ジャーナル
  • Mesenteric panniculitis in systemic lupus erythematosus showing characteristic computed tomography findings
    Nomura, Shun; Shimojima, Yasuhiro; Yoshizawa, Eriko; Kondo, Yasufumi; Kishida, Dai; Sekijima, Yoshiki;
    Lupus, 30(8), 1358-1359, 2021年07月
    責任著者WebofScience電子ジャーナル
  • Primary central nervous system lymphoma in neuropsychiatric systemic lupus erythematosus: case-based review
    Ichikawa, Takanori; Shimojima, Yasuhiro; Kishida, Dai; Kaneko, Tomoki; Sekijima, Yoshiki;
    RHEUMATOLOGY INTERNATIONAL, 41(5), 1009-1017, 2021年05月
    責任著者WebofScience電子ジャーナル
  • Oxidative Stress Promotes Instability of Regulatory T Cells in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
    Shimojima, Yasuhiro; Kishida, Dai; Ichikawa, Takanori; Takamatsu, Ryota; Nomura, Shun; Sekijima, Yoshiki;
    FRONTIERS IN IMMUNOLOGY, 12, 789740, 2021年
    筆頭著者, 責任著者WebofScience電子ジャーナル
  • Cerebrospinal fluid levels of BAFF and APRIL as direct indicators of disease activity in anti-neutrophil cytoplasmic antibody-related hypertrophic pachymeningitis
    Shimojima, Yasuhiro; Kishida, Dai; Nomura, Shun; Sekijima, Yoshiki;
    CLINICAL RHEUMATOLOGY, 39(10), 3145-3148, 2020年10月
    筆頭著者, 責任著者WebofScience電子ジャーナル
  • Clinical characteristics of patients with myalgia as the initial manifestation of small and medium-sized vasculitis: a retrospective study
    Ushiyama, Satoru; Shimojima, Yasuhiro; Ueno, Ken-ichi; Kishida, Dai; Miyazaki, Daigo; Sekijima, Yoshiki;
    RHEUMATOLOGY INTERNATIONAL, 40(10), 1667-1674, 2020年10月
    責任著者WebofScience電子ジャーナル
  • Cerebrospinal fluid biomarkers implicated in the pathogenesis of anti-neutrophil cytoplasmic antibody-related hypertrophic pachymeningitis
    Ikeda, Junji; Shimojima, Yasuhiro; Usami, Yoko; Ueno, Ken-ichi; Kishida, Dai; Sekijima, Yoshiki;
    CLINICAL RHEUMATOLOGY, 39(6), 1803-1811, 2020年06月
    責任著者WebofScience電子ジャーナル
  • Alteration of BAFF and APRIL in the cerebrospinal fluid based on the therapeutic response in primary central nervous system B-cell lymphoma.
    Ikeda J, Shimojima Y, Yoshinaga T, Kodaira M, Nishina S, Ito K, Sekijima Y.
    J Clin Neurosci, 81, 72-75, 2020年
    責任著者
  • Clinical characteristics in patients with myalgia as the initial manifestation of small and medium-sized vasculitis: a retrospective study.
    Ushiyama S, Shimojima Y, Ueno KI, Kishida D, Miyazaki D, Sekijima Y.
    Rheumatol Int, 40, 1667-1674, 2020年
    責任著者
  • Characteristics of Circulating Natural Killer Cells and Their Interferon-gamma Production in Active Adult-onset Still Disease
    Shimojima, Yasuhiro; Kishida, Dai; Ueno, Ken-ichi; Ushiyama, Satoru; Ichikawa, Takanori; Sekijima, Yoshiki;
    JOURNAL OF RHEUMATOLOGY, 46(10), 1268-1276, 2019年
    筆頭著者, 責任著者WebofScience電子ジャーナル
  • Imbalanced expression of dysfunctional regulatory T cells and T-helper cells relates to immunopathogenesis in polyarteritis nodosa
    Shimojima, Yasuhiro; Ishii, Wataru; Kishida, Dai; Fukushima, Kazuhiro; Ikeda, Shu-ichi
    MODERN RHEUMATOLOGY, 27(1), 102-109, 2017年
    筆頭著者, 責任著者電子ジャーナル
  • T-cell receptor-mediated characteristic signaling pathway of peripheral blood T cells in dermatomyositis and polymyositis
    Shimojima, Yasuhiro; Matsuda, Masayuki; Ishii, Wataru; Kishida, Dai; Sekijima, Yoshiki
    AUTOIMMUNITY, 50(8), 481-490, 2017年
    筆頭著者, 責任著者電子ジャーナル
  • Effective Use of Calcineurin Inhibitor in Combination Therapy for Interstitial Lung Disease in Patients With Dermatomyositis and Polymyositis
    Shimojima, Yasuhiro; Ishii, Wataru; Matsuda, Masayuki; Kishida, Dai; Ikeda, Shu-ichi
    JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 23(2), 87-93, 2017年
    筆頭著者, 責任著者電子ジャーナル
  • Hypertrophic pachymeningitis is a characteristic manifestation of granulomatosis with polyangiitis: A retrospective study of anti-neutrophil cytoplasmic antibody-associated vasculitis
    Shimojima, Yasuhiro; Kishida, Dai; Hineno, Akiyo; Yazaki, Masahide; Sekijima, Yoshiki; Ikeda, Shu-ichi
    INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 20(4), 489-496, 2017年
    筆頭著者, 責任著者電子ジャーナル
  • Increased BAFF and APRIL levels in the cerebrospinal fluid of patients with anti-neutrophilcytoplasmic antibody-related hypertrophic pachymeningitis
    Shimojima, Yasuhiro; Kishida, Dai; Sekijima, Yoshiki
    CYTOKINE, 99, 305-309, 2017年, 査読有り
    筆頭著者, 責任著者電子ジャーナル
  • NADPH oxidase deficiency underlies dysfunction of aged CD8(+) Tregs
    Wen, Zhenke; Shimojima, Yasuhiro; Shirai, Tsuyoshi; Li, Yinyin; Ju, Jihang; Yang, Zhen; Tian, Lu; Goronzy, Jorg J.; Weyand, Cornelia M.
    JOURNAL OF CLINICAL INVESTIGATION, 126(5), 1953-1967, 2016年05月, 査読有り
    筆頭著者電子ジャーナル
  • Advantage of administering tacrolimus for improving prognosis of patients with polymyositis and dermatomyositis
    Ueno, Ken-ichi; Shimojima, Yasuhiro; Kishida, Dai; Sekijima, Yoshiki; Ikeda, Shu-ichi
    INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, 19(12), 1322-1330, 2016年
    責任著者電子ジャーナル
  • Regulatory T Cells and the Immune Aging Process: A Mini-Review
    Jagger, Ann; Shimojima, Yasuhiro; Goronzy, Jorg J.; Weyand, Cornelia M.
    GERONTOLOGY, 60(2), 130-137, 2014年
    筆頭著者電子ジャーナル
  • Coadministration of tacrolimus with corticosteroid accelerates recovery in refractory patients with polymyositis/ dermatomyositis: a retrospective study
    Shimojima Y, Ishii W, Matsuda M, Tazawa K, Ikeda S.
    BMC Musculoskelet Disord, 13, 228, 2012年
    筆頭著者電子ジャーナル