Academic Assembly School of Medicine and Health Sciences Institute of Medicine

Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences 



  • Doctor of Medicine, kyoto University

Field Of Study

  • 病態遺伝学(老化病態の分子生物学)

Educational Background

  • 1988, Kyoto University Graduate School of Agriculture, 農学研究科
  • 1993, Kyoto UniversityGraduate School of Medicine, 医学研究科
  • 1986, Kyoto University, Faculty of Agriculture


  • 2023
    老化促進モデルマウス(SAM)学会, 老化促進モデルマウス(SAM)学会 功労賞
    Japan society
    森 政之


  • Renal function in aged C57BL/6J mice is impaired by deposition of age-related apolipoprotein A-II amyloid independent of kidney aging
    Li Y., Dai J., Kametani F., Yazaki M., Ishigami A., Mori M., Higuchi K., Miyahara H.
    Am. J. Pathol., 93, 725-739, 2023, Refereed
  • Macrophages in the reticuloendothelial system inhibit early induction stages of mouse apolipoprotein A-II amyloidosis
    Miyahara H., Dai J., Li Y., Cui X., Takeuchi H., Hachiya N., Kametani F., Yazaki M., Mori M., Higuchi K.
    Amyloid, 30, 225-238, 2023, Refereed
  • Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner
    Mori M., Dai J., Miyahara H., Li Y., Kang X., Yoshimi K., Mashimo T., Higuchi K., Matsumoto K.
    Experimental Animals, 72, 233-241, 2023, Refereed
    Lead, Corresponding
  • BALB.NCT-Cpoxnct is a unique mouse model of hereditary coproporphyria
    Kang X., Shimada S., Miyahara H., Higuchi H., Mori M.
    Mol. Genet. Metab. Rep., 35, 100964, 2023
  • Polygenic control of the wavy coat of the NCT mouse: involvement of an intracisternal A particle insertional mutation of the protease, serine 53 (Prss53) gene, and a modifier gene
    Mori M., Liu C., Yoshizawa T., Miyahara H., Dai J., Igarashi Y., Cui X., Li Y., Kang X., Higuchi K.
    Mammalian Genome, 33, 451-464, 2022, Refereed, Not invited
    Lead, Corresponding電子ジャーナル
  • Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpoxnct mice
    Liu C., Miyahara H., Dai J., Cui X., Li Y., Kang X., Higuchi K., Mori M.
    Exp. Eye Res., 215, 108905, 2022, Refereed, Not invited
    Last, Corresponding電子ジャーナル
  • Exercise suppresses mouse systemic AApoAII amyloidosis through enhancement of the p38 MAPK signaling pathway
    Cui X., Sawashita J., Dai J., Liu C., Igarashi Y., Mori M., Miyahara H., Higuchi K.
    Dis. Model Mech., 15, dmm049327, 2022, Refereed, Not invited電子ジャーナル
  • A Novel Hypothesis on the Molecular Pathogenesis of Porphyria that is Deduced from Studies of a Unique Model Mouse
    Mori Masayuki
    Shinshu Medical Journal, 70(3), 137-144, 2022リポジトリ電子ジャーナル
  • Curcumin promotes AApoAII amyloidosis and peroxisome proliferation in mice by activating the PPARα signaling pathway
    Dai J., Li Y., Kametani F., Cui X., Igarashi Y., Huo J., Miyahara H., Mori M., Higuchi K.
    Elife, 10, e63538, 2021, Refereed
  • Glavonoid-rich oil supplementation reduces stearoyl-coenzyme A desaturase 1 expression and improves systemic metabolism in diabetic, obese KK-Ay mice
    Igarashi Y., Iida S., Dai J., Huo J., Cui X., Sawashita J., Mori M., Miyahara H., Higuchi K.
    Biomed. Pharmacother., 140, 111714, 2021, Refereed, Not invited電子ジャーナル
  • Suppression of mouse AApoAII amyloidosis progression by daily supplementation with oxidative stress inhibitors.
    Dai J., Ding X., Miyahara H., Xu Z., Cui X., Igarashi Y., Sawashita J., Mori M., Higuchi K.
    Oxid. Med. Cell. Longev., 2019, 1263274, 2019, Refereed, Not invited電子ジャーナル
  • Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis
    Miyahara H., Sawashita J., Ishikawa E., Yang M., Ding X., Liu Y., Hachiya N., Kametani F., Yazaki M., Mori M., Higuchi K.
    J. Proteomics, 172, 111-121, 2018, Refereed電子ジャーナル
  • Amyloidosis-inducing activity of blood cells in mouse AApoAII amyloidosis
    Ding X., Liu Y., Yang M., Li L., Miyahara H., Dai J., Xu Z., Matsumoto K., Mori M., Higuchi K., Sawashita J.
    Exp. Anim., 67(2), 105-115, 2018, Refereed電子ジャーナル
  • Coenzyme Q10 Prevents Senescence and Dysfunction Caused by Oxidative Stress in Vascular Endothelial Cells
    Huo J., Xu Z., Hosoe K., Kubo H., Miyahara H., Dai J., Mori M., Sawashita J., Higuchi K.
    Oxid. Med. Cell. Longev., 2018, 3181759, 2018, Refereed電子ジャーナル
  • Apolipoprotein A-II induces acute-phase response associated AA amyloidosis in mice through conformational changes of plasma lipoprotein structure
    Yang M., Liu Y., Dai J., Li L., Ding X., Xu Z., Mori M., Miyahara H., Sawashita J., Higuchi K.
    Sci. Rep., 81(1), 5620, 2018, Refereedリポジトリ電子ジャーナル
  • Caloric restriction reduces the systemic progression of mouse AApoAII amyloidosis
    Li L, Ding X, Yang M, Xu Z, Miyahara H, Mori M, Higuchi K
    PLOS ONE, 12, e0172402, 2017, Refereed電子ジャーナル
  • Apolipoprotein A-II accelerates reactive AA amyloidosis
    Yang Mu, Liu Y, Li L, Miyahara H, Ding X, Dai J, Sawashita J, Mori M, Higuchi K
    Amyloid, 24, 147-148, 2017, Refereed電子ジャーナル
  • Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition.
    Xu Z., Huo J., Ding X., Yang M., Li L., Dai J., Hosoe K., Kubo H., Mori M., Higuchi K., Sawashita J.
    Sci. Rep., 7(1), 8253, 2017, Refereed電子ジャーナル
  • A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2p) in mice
    Shoji H., Kiniwa Y., Okuyama R., Yang M., Higuchi K., Mori M.
    Exp. Anim., 64(2), 171-179, 2015, Refereed
  • C-terminal sequence of amyloid-resistant type F apolipoprotein A-II inhibits amyloid fibril formation of apolipoprotein A-II in mice
    Sawashita J., Zhang B., Hasegawa K., Mori M., Naiki H., Kametani F., Higuchi K.
    Proc. Natl. Acad. Sci. USA., 112(8), E836-E845, 2015, Refereed電子ジャーナル
  • Extracellular deposition of mouse senile AApoAII amyloid fibrils induced different unfolded protein responses in the liver, kidney and heart
    Luo H., Sawashita J., Tian G., Liu Y., Li L., Ding X., Xu Z., Yang M., Miyahara H., Mori M., Qian J., Wang Y., Higuchi K.
    Lab. Invest., 95(3), 320-333, 2015, Refereed電子ジャーナル
  • The factors affecting adherence to a long-term interval walking training program in middle-aged and older people
    Masuki S., Mori M., Tabara Y., Sakurai A., Hashimoto S., Morikawa M., Miyagawa K., Sumiyoshi E., Miki T., Higuchi K., Nose H., Shinshu University Genetic Research Consortium
    J. Appl. Physiol., 118(5), 595-603, 2015, Refereed電子ジャーナル
  • AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform
    Mori M., Tian G., Higuchi K.
    Amyloid, 21(1), 1-8, 2014, Refereed
    Lead, Corresponding電子ジャーナル
  • Ubiquinol-10 supplementation activates mitochondria functions to decelerate senescence in senescence accelerated mice.
    Tian G., Sawashita J., Kubo H., Nishio S., Hashimoto S., Suzuki N., Yoshimura G., Tsuruoka M., Wang Y., Liu Y., Luo H., Xu Z., Mori M., Kitano M., Hosoe K., Takeda T., Usami S., Higuchi K.
    Antioxid. Redox Signal., 20(16), 2606-2620, 2014, Refereed電子ジャーナル
  • A novel frame-shift mutation in Slc5a2 encoding SGLT2 in a strain of Senescence-Accelerated Mouse SAMP10
    Unno K., Yamamoto H., Toda M., Hagiwara S., Iguchi K., Hoshino M., Takabayashi F., Shimada A., Hosokawa M., Higuchi K., Mori M.
    Biochem. Biophys. Res. Commun., 451(1), 89-94, 2014, Refereed電子ジャーナル
  • AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform
    Mori, M; Tiang, G; Higuchi, K
    AMYLOID, 21(1), 1-8, 2014, Refereed
    Lead, CorrespondingWebofScienceリポジトリ電子ジャーナル
  • Diversity and complexity of the mouse Saa1 and Saa2 genes
    Mori M., Tian G., Ishikawa A., Higuchi K.
    Experimental Animals, 63(1), 99-106, 2014, Refereed
    Lead, CorrespondingWebofScienceリポジトリ電子ジャーナル
  • Specific mtDNA Mutations in Mouse Carcinoma Cells Suppress Their Tumor Formation via Activation of the Host Innate Immune System
    Imanishi, H; Takibuchi, G; Kobayashi, T; Ishikawa, K; Nakada, K; Mori, M; Kikkawa, Y; Takenaga, K; Toyama-Sorimachi, N; Hayashi, JI
    PLOS ONE, 8(9), UNSP e75981, 2013, RefereedWebofScienceリポジトリ電子ジャーナル
  • Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes
    Tanisawa, K; Mikami, E; Fuku, N; Honda, Y; Honda, S; Ohsawa, I; Ito, M; Endo, S; Ihara, K; Ohno, K; Kishimoto, Y; Ishigami, A; Maruyama, N; Sawabe, M; Iseki, H; Okazaki, Y; Hasegawa-Ishii, S; Takei, S; Shimada, A; Hosokawa, M; Mori, M; Higuchi, K; Takeda, T; Higuchi, M; Tanaka, M
    BMC GENOMICS, 14, 248, 2013, RefereedWebofScienceリポジトリ電子ジャーナル
  • An interleukin-33 gene polymorphism is a modifier for eosinophilia in rats
    Luo, H; Higuchi, K; Matsumoto, K; Mori, M
    GENES AND IMMUNITY, 14(3), 192-197, 2013, Refereed
  • Hereditary cataract of the Nakano mouse: Involvement of a hypomorphic mutation in the coproporphyrinogen oxidase gene
    Mori, M; Gotoh, S; Taketani, S; Hiai, H; Higuchi, K
    EXPERIMENTAL EYE RESEARCH, 112, 45-50, 2013, Refereed
    Lead, CorrespondingWebofScienceリポジトリ電子ジャーナル
  • Nuclear but Not Mitochondrial DNA Involvement in Respiratory Complex I Defects Found in Senescence-Accelerated Mouse Strain, SAMP8
    IMANISHI Hirotake,YOKOTA Mutsumi,MORI Masayuki,SHIMIZU Akinori,NAKADA Kazuto,HAYASHI Jun-Ichi
    EXPERIMENTAL ANIMALS, 60(4), 397-404, 2011, Refereed
  • ApoA-I deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis
    Wang Yaoyong, Sawashita Jinko, Qian Jinze, Zhang Beiru, Fu Xiaying, Tian Geng, Chen Lei, Mori Masayuki, Higuchi Keiichi
    Journal of Lipid Research, 52(8), 1461-1470, 2011, Refereed
  • Genes for Difference in Eosinophilic Phenotype between MES and BN.MES-Cyba(mes) Rats Are on Chromosomes 9, 5, and 1
    Tomozawa, Hiroshi; Nishio, Ayako; Higuchi, Keiichi; Matsumoto, Kiyoshi; Mori, Masayuki
    EXPERIMENTAL ANIMALS, 60(2), 151-160, 2011, Refereed
  • Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a PPAR-α gene expression signature in SAMP1 mice
    Schmelzer Constance, Kubo Hiroshi, Mori Masayuki, Sawashita Jinko, Kitano Mitsuaki, Hosoe Kazunori, Boomgaarden Inka, Döring Frank, Higuchi Keiichi
    Molecular Nutrition&Food Research, 54(6), 805-815, 2010, Refereed
  • Mouse model to study human Aβ2M amyloidosis: Generation of a transgenic mouse with excessive expression of human β2-microglobulin
    Zhang Pengyao, Fu Xiaying, Sawashita Jinko, Yao Junjie, Zhang Beiru, Qian Jinze, Tomozawa Hiroshi, Mori Masayuki, Ando Yukio, Naiki Hironobu, Higuchi Keiichi
    Amyloid, 17(2), 50-62, 2010, Refereed
  • The reduced form of Coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice
    Schmelzer Constance, Okun Jürgen G., Haas Dorothea, Higuchi Keiichi, Sawashita Jinko, Mori Masayuki, Döring Frank
    IUBMB Life, 62(11), 812-818, 2010, Refereed
  • BN.MES-Cyba(mes) Congenic Rats Manifest Focal Necrosis with Eosinophilic Infiltration in the Liver without Blood Eosinophilia
    Tomozawa, Hiroshi; Nishio, Ayako; Okuhara, Yuji; Higuchi, Keiichi; Matsumoto, Kiyoshi; Mori, Masayuki
    EXPERIMENTAL ANIMALS, 59(4), 469-478, 2010, Refereed
  • Mouse Senile Amyloid Fibrils Deposited in Skeletal Muscle Exhibit Amyloidosis-Enhancing Activity
    Qian, Jinze; Yan, Jingmin; Ge, Fengxia; Zhang, Beiru; Fu, Xiaoying; Tomozawa, Hiroshi; Sawashita, Jinko; Mori, Masayuki; Higuchi, Keiichi
    PLOS PATHOGENS, 6(5), 2010WebofScienceリポジトリ電子ジャーナル
  • Effect of Dietary Unsaturated Fatty Acids on Senile Amyloidosis in Senescence-Accelerated Mice
    Umezawa, M; Higuchi, K; Mori, M; Matushita, T; Hosokawa, M
  • Eosinophilia in the MES rat strain is caused by a loss-of-function mutation in the gene for cytochrome b(-245), alpha polypeptide (Cyba)
    Mori, M., Li, G., Hashimoto, M., Nishio, A., Tomozawa, H., Suzuki, N., Usami, S., Higuchi, K., Matsumoto, K.
    J. Leukoc. Biol., 86(3), 473-478, 2009
    Lead, CorrespondingWebofScience電子ジャーナル
  • Hereditary Pancreatitis Model WBN/Kob Rat Strain Has a Unique Haplotype in the Pdwk1 Region on Chromosome 7
    Mori, M., Fu, X., Chen, L., Zhang, G., Matsumoto, K., Higuchi,K.
    EXPERIMENTAL ANIMALS, 58(4), 409-413, 2009, Refereed
    Lead, CorrespondingWebofScienceリポジトリ電子ジャーナル
  • Amyloid fibrils formed by selective N-, C-terminal sequences of mouse apolipoprotein A-II
    Sawashita, J., Kametani, F., Hasegawa, K., Tsutsumi-Yasuhara, S., Zhang, B., Yan, J., Mori, M., Naiki, H., Higuchi, K.
    Biochim. Biophys. Acta, 1794(10), 1517-1529, 2009, RefereedWebofScienceリポジトリ電子ジャーナル
  • Dysfunction in ABCB1A Has Only a Weak Effect on Susceptibility to Dextran Sulfate Sodium-Induced Colitis in SAM Strains
    Zhang, G., Fu, X., Takeda, T., Higuchi, K., Mori, M.
    EXPERIMENTAL ANIMALS, 58(4), 421-425, 2009, Refereed
  • Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases
    Mori, M., Higuchi, K., Sakurai, A., Tabara, Y., Miki, T., Nose, H.
    Journal of Physiology, 587(23), 5577-5584, 2009
  • Characterization of the cheetah serum amyloid A1 gene: critical role and functional polymorphism of a cis-acting element
    Zhang, B., Une, Y., Ge, F., Fu, X., Qian, J., Zhang, P., Sawashita, J., Higuchi, K., Mori, M.
    J. Hered., 99, 355-363, 2008, Invited
  • Fecal transmission of AA amyloidosis in the cheetah contributes to high incidence of disease
    Zhang, B., Une, Y., Fu, X., Ge, F., Ya,o J., Sawashita, J., Mori, M., Tomozawa, H., Kametani, F., Higuchi, K.
    Proc. Natl. Acad. Sci. USA., 105, 7263-7268, 2008, Refereed
  • Senescence-Accelerated Mouse (SAM) strains have a spontaneous mutation in the Abcb1a gene
    Zhang, G., Zhang, B., Fu, X., Tomozawa, H., Matsumoto, K., Higuchi, K., Mori, M.
    EXPERIMENTAL ANIMALS, 57, 413-417, 2008, Refereed
  • Quantitative trait locus that determines the cross-sectional shape of the femur in SAMP6 and SAMP2 mice
    Otsuki, B., Matsumura, T., Shimizu, M., Mori, M., Okudaira, S., Nakanishi, R., Higuchi, K., Hosokawa, M., Tsuboyama, T., Nakamura, T.
    J. Bone Miner. Res., 22(5), 675-685, 2007, Refereed
  • Amyloidosis in transgenic mice expressing murine amyloidogenic apolipoprotein (Apoa2c)
    Ge, F., Yao, J., Fu, X., Guo, Z., Yan, J., Zhang, B., Zhang, H., Tomozawa, H., Miyazaki, J., Sawashita, J., Mori, M., Higuchi, K.
    Lab. Invest., 87, 633-643, 2007, Refereed
  • Cross-seeding and cross-competition in mouse apolipoprotein A-II amyloid fibrils (AApoAII) and protein A amyloid fibrils (AA)
    Yan, J., Fu, X., Ge, F., Zhang, B., Yao, J., Zhang, H., Qian, J., Tomozawa, H., Naiki, H., Sawashita, J., Mori, M., Higuchi, K.
    Am. J. Pathol., 171, 172-180, 2007, Refereed
  • Functional polymorphisms of the Lss and Fdft1 genes in laboratory rats
    Mori, M., Sawashita, J., Higuchi, K.
    EXPERIMENTAL ANIMALS, 56, 93-101, 2007, Refereed
    Lead, Corresponding
  • Secreted Frizzled-Related Protein 4 is a negative regulator of peak BMD in SAMP6 mice
    Nakanishi, R., Shimizu, M., Mori, M., Akiyama, H., Otsuki, B., Okudaira, S., Hashimoto, M., Higuchi, K., Tsuboyama, T., Nakamura, T
    J. Bone Mineral Res., 21, 1713-1721, 2006, Refereed
  • Transmissibility of mouse AApoAII amyloid fibrils: inactivation by physical and chemical methods
    Zhang H., Sawashita J., Fu X., Korenaga T., Yan J., Mori M., Higuchi K.
    FASEB JOURNAL, 20(7), 1012-1014, 2006, Refereed
  • A third locus for eosinophilia on chromosome 1 ofthe MES rats
    Mori M., Higuchi K., Matsumoto K.
    EXPERIMENTAL ANIMALS, 55(5), 497-500, 2006, Refereed
    Lead, CorrespondingWebofScience
  • Transmission of amyloidosis in offspring of mice with AApoAII amyloidosis
    Korenaga T., Yan J., Sawashita J., Matsushita T., Naiki H., Hosokawa M., Mori M., Higuchi K., Fu X.
    AMERICAN JOURNAL OF PATHOLOGY, 168(3), 898-906, 2006, RefereedWebofScience
  • Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat
    Mori M., Li G., Abe I., Nakayama J., Guo Z., Sawashita J., Ugawa T., Nishizono S., Serikawa T., Higuchi K., Shumiya S.
    JOURNAL OF CLINICAL INVESTIGATION, 116(2), 395-404, 2006, Refereed
    Lead, CorrespondingWebofScience
  • Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice
    Yan J., Fujii K., Yao J., Kishida H., Hosoe K., Sawashita J., Takeda T., Mori M., Higuchi K.
    EXPERIMENTAL GERONTOLOGY, 41(2), 130-140, 2006, RefereedWebofScience
  • Mouse senile amyloidosis: Possible horizontal transmission in the mouse room
    Fu, X; Korenaga, T; Yan, J; Ge, F; Zhang, B; Qian, J; Naiki, H; Sawashita, J; Mori, M; Higuchi, K
    AMYLOID, 13, 29-29, 2006, RefereedWebofScience
  • A locus for eosinophilia in the MES rat is on Chromosome 19
    Li G., Guo Z., Higuchi K., Kawakubo M., Matsumoto K., Mori M.
    MAMMALIAN GENOME, 16(7), 516-523, 2005, Refereed
  • Analysis of murine chromosomes 11 and 13 loci that control peak bone mass
    Shimizu, M; Nakanishi, R; Otsuki, B; Nakamura, T; Hosokawa, M; Mori, M; Higuchi, K; Tsuboyama, T
    BONE, 36, S398-S399, 2005, RefereedWebofScience
  • Establishment of a set of combined immunodeficient DA/Slc-Foxn1rnu Lystbg congenic rat strains
    Masui N., Nishikawa T., Takagi Y., Kimura H., Mori M., Yokose S., Asai H., Yanabe M., Sato K.
    EXPERIMENTAL ANIMALS, 53(5), 399-407, 2004, RefereedWebofScience
  • Mouse testis transcriptome revealed using serial analysis of gene expression
    Yao J., Chiba T., Sakai J., Hirose K., Yamamoto M., Hada A., Kuramoto K., Higuchi K., Mori M.
    MAMMALIAN GENOME, 15(6), 433-451, 2004, Refereed
  • Tissue distribution, biochemical properties, and transmission of mouse type A AApoAII amyloid fibrils
    Korenaga T., Fu X., Xing Y., Matsusita T., Kuramoto K., Shumiya S., Hasegawa K., Naiki H., Ueno M., Ishihara T., Hosokawa M., Mori M., Higuchi K.
    AMERICAN JOURNAL OF PATHOLOGY, 164(5), 1597-1606, 2004, RefereedWebofScience
  • Induction of AApoAII amyloidosis by various heterogeneous amyloid fibrils
    Fu X., Korenaga T., Fu L., Xing Y., Guo Z., Matsushita T., Hosokawa M., Naiki H., Baba S., Kawata Y., Ikeda S., Ishihara T., Mori M., Higuchi K.
    FEBS Letter, 563(1-3), 179-184, 2004, RefereedWebofScience
  • An allele-specific genotyping method for rat Lyst (lysosomal trafficking regulator) gene
    Masui N., Mori M., Nishikawa T., Takagi Y., Asai H., Yanabe M., Yamasaki K., Serikawa T., Sato K.
    EXPERIMENTAL ANIMALS, 53(1), 77-80, 2004, RefereedWebofScience
  • 多因子遺伝性疾患モデルとしての白内障ラットの解析
    森 政之
    信州医学雑誌, 51(2), 105-106, 2003, Refereed
    Lead, Corresponding
  • 遺伝的解析のモデル生物、マウス
    森 政之, 芹川忠夫
    遺伝子医学別冊「これだけは知っておきたい遺伝子医学の基礎知識」, 154-158, 2003
  • A new beige mutant rat ACI/N-Lystbg-Kyo
    Mori M., Yamasaki K., NakanishiS., Kitada K., Higuchi K., Namiki C., Hamada S., Serikawa T.
    EXPERIMENTAL ANIMALS, 52(1), 32-36, 2003, Refereed
    Lead, CorrespondingWebofScience
  • Quantitative trait locus analysis of serum insulin triglyceride, total cholesterol and phospholipid levels in the (SM/J x A/J)F2 mice
    Anunciad RVP., Nishimura M., Mori M., Ishikawa A., Tanaka S., Horio F., Ohno T., Namikawa T.
    EXPERIMENTAL ANIMALS, 52(1), 37-42, 2003, RefereedWebofScience
  • The rat lysosomal trafficking regulator (Lyst) gene is mapped on the telomeric region of chromosome 17
    Masui N., Nishikawa T., Takagi Y., MoriM., Suzuki T., Sato K.
    EXPERIMENTAL ANIMALS, 52(1), 89-91, 2003, RefereedWebofScience
  • Amyloidosis modifier genes in less amyloidogenic A/J mouse strain
    Guo Z., Mori M., Fu X., Yao J., Xing Y., Korenaga T., Li G., Matsushita T., Hosokawa M., Higuchi K.
    LABORATORY INVESTIGATION, 83(11), 1605-1613, 2003, RefereedWebofScience
  • Spontaneous hypomorphic mutations in antioxidant enzymes of mice
    Guo Z., Higuchi K., Mori M.
    Free Radical Biology&Medicine, 35(12), 1645-1652, 2003, Refereed
  • Polymorphisms of mouse apolipoprotein A-II: seven alleles found among 41 inbred strains of mice
    Kitagawa K., Wang J., Matsushita T., Kogishi K., Hosokawa M., Fu X., Guo Z., Mori M., Higuchi K.
    Amyloid, 10(4), 207-214, 2003, RefereedWebofScience
  • 老化疾患モデル ーマウス
    森 政之, 樋口京一
    現代医療, 34(2), 37-42, 2002
    Lead, Corresponding
  • 老化疾患モデルマウス
    森 政之, 樋口京一
    Molecular Medicine, 39(5), 528-533, 2002
  • Chediak-Higashi症候群とベージュミュータント動物
    森 政之
    別冊・医学のあゆみ 免疫疾患-state of arts ver. 2, 303-306, 2002
    Lead, Corresponding
  • A congenic mouse and candidate gene at the chr 13 locus regulating bone density
    Shimizu M., Higuchi K., Tsuboyama T., Matsushita M., Kasai S., Matsuura T., Okudaira S., Mori M., Koizumi A., Nakamura T., Hosokawa M.
    MAMMALIAN GENOME, 13(7), 335-340, 2002, RefereedWebofScience
  • Induction of protein conformational change in mouse senile amyloidosis
    Xing Y., Nakamura A., Korenaga T., Guo Z., Yao J., Fu X., Matsushita T., Kogish K., Hosokawa M., Kametani F., Mori M., Higuchi K.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 277(36), 33164-33169, 2002, RefereedWebofScience
  • 老化促進マウス(SAM)の解析
    樋口京一, 森 政之
    BIO Clinica, 16(9), 57-61, 2001
  • Extra-hepatic expression of apolipoprotein A-II in mouse tissues: Possible contribution to mouse senile amyloidosis
    L. Fu, I. Matsuyama, T. Chiba, Y. Xing, T. Korenaga, Z. Guo, J. Nakayama, M. Mori, K. Higuchi
    Journal of Histochemitry and Cytochemistry, 49(6), 739-748, 2001, Refereed
  • マウスを用いた老化・寿命の分子遺伝学的研究
    森 政之, 樋口京一
    基礎老化研究, 25(2), 77-82, 2001
    Lead, Corresponding
  • Spontaneous Loss-of-Function Mutations of the 8-Oxoguanine DNA Glycosylase Gene in Mice and Exploration of the Possible Implication of the Gene in Senescence
    M. Mori, S. Toyokuni, S. Kondo, H. Kasai, H. Naiki, E. Toichi , M. Hosokawa, K. Higuchi
    Free Radical Biology&Medicine, 30(10), 1130-1136, 2001, Refereed
    Lead, CorrespondingWebofScience
  • Quantitative trait locus analysis for chronic pancreatitis and diabetes mellitus in the WBN/Kob rat
    A. Tsuji, T. Nishikawa, M. Mori, K. Suda, I. Nishimori, M. Nishimura
    GENOMICS, 74(3), 365-369, 2001WebofScience
  • Transmission of Mouse Senile Amyloidosis
    Y. Xing, A. Nakamura, T. Chiba, K. Kogishi, T. Matsushita, L. Fu, Z. Guo, M. Hosokawa, M. Mori, K. Higuchi
    LABORATORY INVESTIGATION, 81(4), 493-499, 2001, RefereedWebofScience
  • Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains
    J. Mizutani, T. Chiba, M. Tanaka , K. Higuchi, M. Mori
    JOURNAL OF HEREDITY, 92(4), 352-355, 2001, Refereed
  • Quantitative trait loci for body weight in the intercross between SM/J and A/J mice
    Anunciado, R.V.P., Nishimura, M., Mori, M., Ishikawa, A., Tanaka, S., Horio, F., Ohno, T.,Namikawa, T.
    EXPERIMENTAL ANIMALS, 50(4), 319-324, 2001, RefereedWebofScience
  • Chromosome 13 locus, Pbd2, regulates bone density in mice
    Shimizu M., Higuchi K., Kasai S., Tsuboyama T., Matsushita M., Mori M., Shimizu Y., Nakamura T., Hosokawa M.
    JOURNAL OF BONE AND MINERAL RESEARCH, 16, 1972-1982, 2001, RefereedWebofScience
  • Transmission of Mouse Senile Amyloidosis
    Xing, YM; Nakamura, A; Chiba, T; Korenaga, T; Kogishi, K; Matsushita, T; Fu, L; Guo, ZJ; Hosokawa, M; Mori, M; Higuchi, K
    AMYLOID, 8, 22-22, 2001, RefereedWebofScience
  • Extrahepatic expression of apolipoprotein A-II in mouse tissues: Possible contribution to mouse senile amyloidosis
    Fu, L; Matsuyama, I; Chiba, T; Xing, YM; Korenaga, T; Guo, ZJ; Fu, XY; Nakayama, J; Mori, M; Higuchi, K
    JOURNAL OF HISTOCHEMISTRY&CYTOCHEMISTRY, 49(6), 739-747, 2001, RefereedWebofScience
  • ApoA-II gene does not rescue Senescence-Accelerated Mouse (SAMP1) from short life span and accelerated mortality
    Wang J., Matsushita T., Kogishi K., Xia C., Ohta A., Chiba T., Nakamura A., Kondoh H., Mori M., Hosokawa M., Higuchi K.
    Journal of Gerontology. B Biological Science, 55A(9), B432-B439, 2000, Refereed
  • Genetic Analysis of Lifespan in Hybrid Progeny Derived From the SAMP1 Mouse Strain with Accelerated Senescence
    Z. Guo, E. Toichi, M. Hosono, T. Hosokawa, M. Hosokawa, K. Higuchi, M. Mori
    Mechanism of Ageing and Development, 118(1-2), 35-44, 2000, Refereed
  • Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis
    Anunciado RVP., Ohno T., Mori M., Ishikawa A., Tanaka S., Horio F., Nishimura M., Namikawa T.
    EXPERIMENTAL ANIMALS, 49(3), 217-224, 2000, RefereedWebofScience
  • Wild type ApoA-II gene does not rescue senescence-accelerated mouse (SAMP1) from short life span and accelerated mortality
    Wang, J; Matsushita, T; Kogishi, K; Xia, C; Ohta, A; Chiba, T; Nakamura, A; Kondo, H; Mori,M; Hosokawa, M; Higuchi, K
  • Deletion in the beige gene of the beige rat owing to recombination between LINE1s
    Mori M., Nishikawa T., Higuchi K., Nishimura M
    MAMMALIAN GENOME, 10(7), 692-695, 1999, Refereed
    Lead, CorrespondingWebofScience
  • わが国が貢献したマウスラットの疾患遺伝子の情報
    森 政之, 西村正彦, 西川 哲
    アニテックス, 10(2), 25-29, 1998
    Lead, Corresponding
  • Genetic profile of the SMXA recombinant inbred mouse strains revealed with restriction landmark genomic scanning
    Mori M., Akiyoshi S., Mizuno Y., Okuizumi H., Okazaki Y., Hayashizaki Y., Nishimura M
    MAMMALIAN GENOME, 9(9), 695-709, 1998, Refereed
    Lead, Corresponding

Books and other publications

  • Biophysical Inquiry into Protein Aggregation and Amyloid Diseases
    Higuchi, K., Fu, X., Zhang, B., Sawashita J, Mori, M., Joint work, Genetics and transmission of mouse systemic amyloidosis
    Research SignPost, 253-267 2008
  • XIth International Symposium on Amyloidosis
    Fu, X., Korenaga, T., Yan, J., Ge, F., Zhan, B., Qian, J., Naiki, H., Sawashita, J., Mori, M., Higuchi, K., Joint work, Mouse senile amyloidosis: possible horizontal transmission in the mouse room
    CRC Press, 10-12 2007
  • XIth International Symposium on Amyloidosis
    Higuchi, K., Ge, F., Fu, X., Yao, J., Zhan, B., Zhan, H., Qian, J., Sawashita, J., Mori, M., Joint work, Amyloidosis in the transgenic mice of mouse amyloidgenic apolipoprotein A-II (Apoa2C)
    CRC Press, 143-145 2007
  • Transmission of Mouse AApoAII Amyloidosis by the Amyloid Fibrils; Inhibitory Effects on Transmission by the Denaturation/Degradation of Amyloid FibrilsGrateau G, Kyle RA, Skinner M eds: Amyloid and Amyloidosis
    Sawashita J, Zhang H, Fu X, Korenaga T, Mori M, Higuchi K, Joint work
    CRC Press, Boca Raton, pp 457-459 2005
  • Transmission of Mouse AApoAII Amyloidosis from Mother to Pups. Grateau G, Kyle RA, Skinner eds: Amyloid and Amyloidosis
    Korenaga T, Fu X, Mori M, Sawashita J, Naiki H, Matsushita T, Higuchi K, Joint work
    CRC Press, Boca Raton,, pp 457-459 2005
  • Nomura Y, Takeda T, Okuma Y ed.: The Senescence-Accelerated Mouse(SAM): An animal model of senescence
    Higuchi K, Xing Y, Fu X, Korenaga T, Guo Z, Nakamura A, Mori M, Joint work, Mouse senile amyloidosis in the SAM model
    Elsevier, Amsterdam, pp 35-40 2004
  • Nomura Y, Takeda T, Okuma Y ed.: The Senescence-Accelerated Mouse(SAM): An animal model of senescence
    Mori M, Higuchi K, Joint work, Genetic monitoring system for SAM strains utilizing DNA markers
    Elsevier, Amsterdam, pp 187-190 2004
  • Nomura Y, Takeda T, Okuma Y ed.: The Senescence-Accelerated Mouse(SAM): An animal model of senescence
    Fu X, Korenaga T, Xing Y, Fu L, Guo Z, Matsushita T, Hosokawa M, Naiki H, Mori M, Higuchi K, Joint work, Induction of AApoAⅡ and AA amyloidosis by the injection of various amyloid fibrils
    Elsevier, Amsterdam, pp 383-386 2004
  • 森脇和郎,山村研一,米川博通編:モデル動物の作製と維持
    樋口京一,森 政之, Joint work, SAM(老化促進モデルマウス)
    エル・アイ・シー,東京, pp 929-936 2004
  • モデル動物の作製と維持
    森脇和郎、山村研一、米川博通編, Joint work
    エル・アイ・シー,東京, 929-936 2004
  • 老年医学テキスト
    社団法人日本老年医学会編, Joint work
    メジカルビュー社, 17-19 2003

Affiliated academic society

  • 老化促進モデルマウス(SAM)学会

Research Themes

  • 病態遺伝学(老化病態の分子生物学)