工学博士, 九州大学

有機合成化学

構造有機化学、物理有機化学, 有機化学

2006年
信州大学 教授

1998年
信州大学 助手

1998年
信州大学 助教授

1996年
大阪大学大学院 （理学研究科） 助手

1994年
大阪大学 （理学部） 助手

1988年
九州大学 教務員

1988年
大阪大学 （教養部） 助手

1996年, ミシガン大学

1988年, 九州大学, 総合理工学研究科

1985年, 九州大学, 総合理工学研究科

1983年, 山口大学, 工学部

Mechanistic Insights into Urea-, Thiourea-, and Isothiourea-Based Bifunctional Tetraarylphosphonium Salt Catalysis for Conversion of Carbon Dioxide to Cyclic Carbonates
Yasunori TODA, Daiki SUENAGA, Ren YAMAGUCHI, Hiroyuki SUGA
Eur. J. Org. Chem., 27(16), e202400137-e202400137, 2024年

Ring-fused hexahydro-1,2,4,5-tetrazines: synthesis, structure, and mechanistic studies on isolable rotational isomers
Yasunori Toda, Airi Kooguchi, Kimiya Sukegawa, Ayaka Kikuchi, Hiroyuki Suga
Chem. Commun., 59(6), 700-703, 2023年

Visible-Light-Driven C-H Imidation of Arenes and Heteroarenes by a Phosphonium Ylide Organophotoredox Catalyst: Application to C-H Functionalization of Alkenes
Yasunori Toda, Toya Kobayashi, Fumiya Hirai, Takamichi Yano, Makoto Oikawa, Kimiya Sukegawa, Masahiro Shimizu, Fuyuki Ito, Hiroyuki Suga
J. Org. Chem., 88(13), 9574-9578, 2023年

多機能な分子性触媒を志向したホスホニウムイリドの創製
戸田泰徳，菅　博幸
有機合成化学協会誌, 81(4), 333-340, 2023年

Visible-Light-Driven C–H Imidation of Arenes and Heteroarenes by a Phosphonium Ylide Organophotoredox Catalyst: Application to C–H Functionalization of Alkenes
Yasunori TODA, Toya KOBAYASHI, Fumiya HIRAI, Takamichi YANO, Makoto OIKAWA, Kimiya SUKEGAWA, Masahiro SHIMIZU, Fuyuki ITO, Hiroyuki SUGA
J. Org. Chem., 88(13), 9574-9578, 2023年

Base-mediated Synthesis of Cyclic Dithiocarbamates from 1-Amino-3-chloropropan-2-ol Derivatives and Carbon Disulfide
Yasunori TODA, Masaya IWASAKI, Hiroyuki SUGA
Org. Biomol. Chem., 21(31), 6293-6297, 2023年

Development of Phosphonium Ylides as Multifunctional Organocatalysts
Yasunori TODA, Hiroyuki SUGA
J. Synth. Org. Chem. Jpn., 81, 333-340, 2023年

Asymmetric Cycloadditions of Acyclic Carbonyl Ylides with Aldehydes Catalyzed by a Chiral Binaphthyldiimine-Ni(II) Complex: Enantioselective Synthesis of 1,3-Dioxolanes and Mechanistic Studies by DFT Calculations
Yasunori Toda, Kayo Sato, Kensuke Sato, Kazuma Nagasaki, Hirotaka Nakajima, Ayaka Kikuchi, Kimiya Sukegawa, Hiroyuki Suga
Org. Lett., 24(26), 4739-4744, 2022年

A phosphonium ylide as a visible light organophotoredox catalyst: A mechanistic study
Yasunori Toda, Katsumi Tanaka, Riki Matsuda, Tomoyuki Sakamoto, Shiho Katsumi, Masahiro Shimizu, Fuyuki Ito, Hiroyuki Suga
Chem. Commun., 57(19), 3591-3594, 2021年

Enantioselective Protonation of Cyclic Carbonyl Ylides by Chiral Lewis Acid Assisted Alcohols
Yasunori Toda, Takayuki Yoshida, Kaoru Arisue, Kazuaki Fukushima, Hiroyoshi Esaki, Ayaka Kikuchi, Hiroyuki Suga
Chem. Eur. J., 27(41), 10578-10582, 2021年

Switchable synthesis of cyclic carbamates by carbon dioxide fixation at atmospheric pressure
Yasunori Toda, Minoru Shishido, Tatsuya Aoki, Kimiya Sukegawa, Hiroyuki Suga
ROYAL SOC CHEMISTRY, 57(54), 6672-6675, 2021年

A phosphonium ylide as a ligand for [3 + 2] coupling reactions of epoxides with heterocumulenes under mild conditions
Yasunori Toda, Kousuke Hashimoto, Yoko Mori, Hiroyuki Suga
J. Org. Chem., 85(16), 10980-10987, 2020年

Synthesis of 1,2,5-Oxadiazinane Derivatives by Photochemical Cycloaddition of Nitrones with Diaminomethanes
Kennosuke Itoh, Atsushi Takashino, Atsushi Ohtsuka, Mizuki Kobe, Shunsuke Sawamura, Ryo Kato, Shigeto Hirayama, Fumika Karaki, Takaaki Mizuguchi, Noriko Sato, Ken Tokunaga, Yasunori Toda, Hiroyuki Suga, Hitoshi Ishida, Hideaki Fujii
CHEMPHOTOCHEM, 4(6), 388-392, 2020年

Enantioselective synthesis of 8-azabicyclo[3.2.1]octanes via asymmetric 1,3-dipolar cycloadditions of cyclic azomethine ylides using a dual catalytic system
Hiroyuki SUGA, Masahiro YOSHIWARA, Takaaki YAMAGUCHI, Takashi BANDO, Mizuki TAGUCHI, Ayano INABA, Yuichi GOTO, Ayaka KiKUCHI, Kennosuke ITOH, Yasunori TODA
Chem. Commun., 55(11), 1552-1555, 2019年

Use of trichloroacetonitrile as a hydrogen chloride generator for ring-opening reactions of aziridines
Yasunori TODA, Riki MATSUDA, Shuto GOMYOU, Hiroyuki SUGA
Org. Biomol. Chem., 17(15), 3825-3829, 2019年

Novel Asymmetric Photodimerization Reaction of Coumarin Derivatives Bearing a Chiral 2-Oxazolidinone Auxiliary
Kennosuke ITOH, Fumiya ODATE, Takuma KARIKOMI, Keishi OBE, Tsutomu MIYAMORI, Hideaki KAMIYA, Kenji YOZA, Kenichiro NAGAI, Hideaki FUJII, Hiroyuki SUGA, Ken TOKUNAGA
RSC Adv., 9(22), 12365-12369, 2019年

4-Hydroxymethyl-substituted oxazolidinone synthesis by tetraarylphosphonium salt-catalyzed reactions of glycidols with isocyanates
Yasunori TODA, Shoya TANAKA, Shuto GOMYOU, Ayaka KIKUCHI, Hiroyuki SUGA
Chem. Commun., 55(41), 5761-5764, 2019年

Visible-light-triggered Catalytic Halohydrin Synthesis from Epoxides and Trichloroacetonitrile by Copper and Iron Salts
Yasunori Toda, Katsumi Tanaka, Riki Matsuda, Hiroyuki Suga
Chem. Lett., 48(12), 1469-1471, 2019年

Methoxy Groups Increase Reactivity of Bifunctional Tetraarylphosphonium Salt Catalysts for Carbon Dioxide Fixation: A Mechanistic Study
Yasunori Toda, Yutaka Komiyama, Hiroyoshi Esaki, Kazuaki Fukushima, Hiroyuki Suga
J. Org. Chem., 84(23), 15578-15589, 2019年

Three-Component Reactions of Diazoesters, Aldehydes, and Imines Using a Dual Catalytic System Consisting of a Rhodium(II) Complex and a Lewis Acid
Yasunori TODA, Wakatake KAKU, Makoto TSURUOKA, Sho SHINOGAKI, Tomoka ABE, Hideaki KAMIYA, Ayaka KIKUCHI, Kennosuke ITOH, Hiroyuki SUGA
Org. Lett., 20(9), 2659-2662, 2018年

ENANTIOSELECTIVE CYCLOADDITIONS BETWEEN ALIPHATIC NITRILE OXIDES AND 2-HYDROXYSTYRENES CATALYZED BY CHIRAL AMINE-UREA
Yasunori TODA, Masato KOYAMA, Hiroyoshi ESAKI, Kazuaki FUKUSHIMA, Hiroyuki SUGA
Heterocycles, 97(1), 147-150, 2018年

Lewis Acid Catalysis in Intermolecular [2+2] Photocycloaddition of Coumarin-3-carboxamide Bearing 2-Oxazolidinone Auxiliary with n-Propyl Vinyl Ether and Vinyl Pivalate
Kennosuke ITOH, Junya MATSUURA, Hideaki KAMIYA, Ryuki KUDO, Yuki TAKAHASHI, Yuta HASHIMOTO, Kenji YOZA, Ken TOKUNAGA, Hideaki FUJII, Hiroyuki SUGA
Heterocycles, 97(1), 591-603, 2018年

Efficient generation of an oxidopyrylium ylide using a Pd catalyst and its [5+2] cycloadditions with several dipolarophiles
Hiroyuki Suga, Taichi Iwai, Masahiro Shimizu, Kie Takahashi, Yasunori Toda
Chem. Commun., 54(9), 1109-1112, 2018年

Triethylamine Enables Catalytic Generation of Oxidopyrylium Ylides for [5+2] Cycloadditions with Alkenes: An Efficient Entry to 8-Oxabicyclo[3.2.1]octane Frameworks
Yasunori TODA, Masahiro SHIMIZU, Taichi IWAI, Hiroyuki SUGA
Adv. Synth. Catal., 360(12), 2377-2381, 2018年

A Phosphonium Ylide as an Ionic Nucleophilic Catalyst for Primary Hydroxyl Group Selective Acylation of Diols
Yasunori Toda, Tomoyuki Sakamoto, Yutaka Komiyama, Ayaka Kikuchi, Hiroyuki Suga
ACS Catal., 7(9), 6150-6154, 2017年

Tetraarylphosphonium Salt-Catalyzed Synthesis of Oxazolidinones from Isocyanates and Epoxides
Yasunori Toda, Shuto Gomyou, Shoya Tanaka, Yutaka Komiyama, Ayaka Kikuchi, Hiroyuki Suga
Org. Lett., 19(21), 5786-5789, 2017年

Amine‐Urea‐Mediated Asymmetric Cycloadditions between Nitrile Oxides and o‐Hydroxystyrenes by Dual Activation
Hiroyuki Suga, Yohei Hashimoto, Yasunori Toda, Kazuaki Fukushima, Hiroyoshi Esaki, Ayaka Kikuchi
Angew. Chem. Int. Ed., 56(39), 11936-11939, 2017年

Tetraarylphosphonium Salt-Catalyzed Carbon Dioxide Fixation at Atmospheric Pressure for the Synthesis of Cyclic Carbonates
Yasunori Toda, Yutaka Komiyama, Ayaka Kikuchi, and Hiroyuki Suga
ACS CATALYSIS, 6(10), 6906-6910, 2016年

Chiral Lewis Acid-Catalyzed Enantioselective Cycloadditions between Indoles and Cyclic Carbonyl Ylides Derived from Diazodiketone or Diazoketoester Derivatives
Hiroyuki SUGA, Yurie SEKIKAWA, Shunta MISAWA, Daito KINUGAWA, Rinnosuke ODA, Kennosuke ITOH, Yasunori TODA, Ryotaro KIYONO
J. Org. Chem., 80(13), 6687-6696, 2015年

Photochemically-induced C–C Bond Formation between Tertiary Amines and Nitrones
Kennosuke ITOH, Ryo KATO, Daito KINUGAWA, Hideaki KAMIYA, Ryuki KUDO, Masayuki HASEGAWA, Hideaki FUJIIA, Hiroyuki SUGA
Org. Biomol. Chem., 13(33), 8919-8924, 2015年

Diastereoselective Synthesis of Tetrahydrofurans by Lewis Acid Catalyzed Intermolecular Carbenoid−Carbonyl Reaction−Cycloaddition Sequences: Unusual Diastereoselectivity of Lewis Acid Catalyzed Cycloadditions
Yuta HASHIMOTO, Kennosuke ITOH, Akikazu KAKEHI, Motoo SHIRO, Hiroyuki SUGA
J. Org. Chem., 78(12), 6182-6195, 2013年

Chiral Lewis Acid Catalyzed Asymmetric Cycloadditions of Carbonyl Ylides Generated from Diazoimide Derivatives and their Synthetic Applications to Indolizidine Alkaloids
Hiroyuki SUGA, Yuta HASHIMOTO, Shingo YASUMURA, Ryota TAKEZAWA
J. Org. Chem., 78(21), 10840-10852, 2013年

Molecular Recognition of 2-(Arylmethylthio)indolizine Derivatives Through an Intramolecular Aene-(cation) Interaction
Akikazu KAKEHI, Kennosuke ITOH, Hiroyuki SUGA, Nobuhiro YAMAGUCHI, Takashi ABE, Yohei YUDA, Haruka KATSUMATA
Heterocycles, 84(2), 753-764, 2012年

Novel Rearrangements of a 8aH-Pyrido[1,2-d]thieno[2’,3’-b][1,4]thiazepine Derivative
Akikazu KAKEHI, Kennosuke ITOH, Hiroyuki SUGA, Yuuki OHKUBO, Ayaka KOBAYASHI, Takashi NISHI
Heterocycles, 85(2), 305-312, 2012年

A New Synthetic Approch to Some Functionalized Cyclo[3.2.2]azine Derivatives
Hideyuki MURANAKA, Akikazu KAKEHI, Hiroyuki SUGA, Kennosuke Itoh
Heterocycles, 82(2), 1251-1266, 2011年

Unexpected Formation of Thiino[3’,4’:4,5]oxazolo[1,3-b][1,3]oxazepine Derivatives
Akikazu KAKEHI, Kennosuke ITOH, Hiroyuki SUGA, Hirofumi KOBAYASHI, Hideyuki MURANAKA
Heterocycles, 83(3), 1013-1016, 2011年

Asymmetric Cycloaddition Reactions of Diazoesters with 2-Alkenoic Acid Derivatives Catalyzed by Binaphthyldiimine Ni(II) complexes
Hiroyuki Suga, Yasuhisa Furihata, Atsushi Sakamoto, Kennosuke Itoh, Yukihisa Okumura, Teruko Tsuchida, Akikazu Kakehi, Toshihide Baba
J. Org. Chem., 76(18), 7377–7387, 2011年

Synthesis of Spiro[2-cyclopentene-1,3’-imidazo[1,2-a]pyridine] Derivatives and Their Interesting Behavior in 1H-NMR Spectra in Deuteriochloroform
Abe, T.; Kakehi, A.; Suga, H.; Okumura, Y.; Itoh, K.
Heterocycles, 81(9), 2075-2086, 2010年09月

ASYMMETRIC 1,3-DIPOLAR CYCLOADDITION REACTIONS OF AZOMETHINE IMINES WITH ACROLEIN CATALYZED BY L-PROLINE AND ITS DERIVATIVES
Hiroyuki SUGA, Tadashi ARIKAWA, Kennosuke ITOH, Yukihisa OKUMURA, Akikazu KAKEHI, Motoo SHIRO
Heterocycles, 81(7), 1669-1688, 2010年07月

Inverse electron demand asymmetric cycloadditions of cyclic carbonyl ylides catalyzed by chiral Lewis acids-Scope and limitations of diazo and olefinic substrates
Suga, H; Higuchi, S; Ohtsuka, M; Ishimoto, D; Arikawa, T; Hashimoto, Y; Misawa, S; Tsuchida, T; Kakehi, A; Baba, T
Tetrahedron, 66(16), 3070-3089, 2010年04月

A New Approach to Imidazo[1,2-a]pyridine Derivatives and Their Application to the Syntheses of Novel 2H-Pyrano[2’,3’:4,5]imidazo[1,2-a]pyridin-2-one Derivatives
Abe, T.; Okumura, Y.; Suga, H.; Kakehi, A.
Heterocycles, 80(1), 439-454, 2010年01月

PREPARATION OF NEW NITROGEN-BRIDGED HETEROCYCLES. 68. ONE-POT SYNTHSIS OF 4-SUBSTITUTED 5-ACYLTHIENO[3,2-d]THIAZOLE DERIVATIVES
Kakehi, A; Suga, H; Okumura, Y; Nishi, T
Heterocycles, 81(1), 175-184, 2010年01月

Preparation of new nitrogen-bridged heterocycles. 72. A New Approach to 1-Acyl-3-(substituted methylthio)thieno[3',4':4,5]imidazo[1,5-a]pyridine Derivatives
Akikazu KAKEHI, Hiroyuki SUGA, Yukihisa OKUMURA, Kennosuke ITOH, Kouji KOBAYASHI, Yoshihiro AIKAWA, Kotaro MISAWA
Chem. Pharm. Bull., 58(11), 1502-1510, 2010年

Asymmetric 1,3-Dipolar Cycloaddition Reactions of Nitrile Oxides Catalyzed by Chiral Binaphthyldiimine-Ni(II) Complexes
Hiroyuki SUGA, Yuki ADACHI, Kouhei FUJIMOTO, Yasuhisa FURIHATA, Teruko TSUCHIDA, Akikazu KAKEHI, Toshihide BABA
J. Org. Chem., 74(3), 1099-1113, 2009年

Preparation of New Nitrogen-bridged Heterocycles 64. A Smooth Formation of 2,4-Diarylpyrido[2,3-b]indolizine-10-carbonitrile Derivatives
Akikazu KAKEHI, Hiroyuki SUGA, Shuichi SATO
Heterocycles, 77(1), 471-481, 2009年

First Formation of Thiepino[2,3-b]- and Thiepino[3,2-a]indolizine Derivatives
Hidetoshi ISAWA, Hiroyuki SUGA, Akikazu KAKEHI
Heterocycles, 78(2), 319-324, 2009年

Preparation of New Nitrogen-bridged Heterocycles 67. Syntheses of ,’-Bis-o-, m-, and p-xylene Derivatives and Their Conformational Structures
Akikazu KAKEHI, Hiroyuki SUGA, Yukihisa OKUMURA, Masatoshi SHINOHARA, Tomonao KAKO, Takeshi SEKIGUCHI, Motoo SHIRO
Chem. Pharm. Bull., 57(12), 1385-1390, 2009年

Reaction of Potassium Pyrazolo[1,5-a]pyridine-2-thiolates with Electron-poor Alkynes
Hidetoshi ISAWA, Akikazu KAKEHI, Hiroyuki SUGA
Hetreocyclic Commun., 14(3), 141-148, 2008年

Preparation of New Nitrogen-bridged Heterocycles 63. Unexpected Formation of Thieno[3’,4’:4,5]imidazo[1,2-a]pyridines
Akikazu KAKEHI, Hiroyuki SUGA, Atsushi Izumida, Takashi Abe
Heterocycles, 76(1), 391-399, 2008年

Lewis Acid-Catalyzed Michael Addition Reactions of N-Boc-2-silyloxypyrroles to 3-Acryloyl-2-oxazolidinone
Suga H., Takemoto H, Kakehi A.
Heterocycles, 71(2), 361-371, 2007年01月

Highly Enantioselective and Diastereoselective 1,3-Dipolar Cycloaddition Reactions between Azomethine Imines and 3-Acryloyl-2-oxazolidinone Catalyzed by Binaphthyldiimine-Ni(II) Complexes
Hiroyuki SUGA, Akira FUNYU, Akikazu KAKEHI
Org. Lett., 9(1), 97-100, 2007年

Dipole-LUMO/Dipolarophile-HOMO Controlled Asymmetric Cycloadditions of Carbonyl Ylides Catalyzed by Chiral Lewis Acids
Hiroyuki SUGA, Daisuke ISHIMOTO, Satoshi HIGUCHI, Motoo OHTSUKA
Org. Lett., 9(21), 4359-4362, 2007年

Preparation of New Nitrogen-bridged Heterocycles 59. Syntheses and Intramolecular Interactions of 3-(Acylmethylthio)- and 3-[(3-Ethoxycarbonyl-2-propenyl)thio]thieno[3,4-b]indolizine Derivatives
Akikazu KAKEHI, Hiroyuki SUGA, Hirohide, ISOGAI
Chem. Pharm. Bull., 55(1), 95-101, 2007年

Syntheses and Conformational Analyses of Bis(indolizin-1-yl) Disulfides
Akikazu KAKEHI, Hiroyuki SUGA, Hiroko OKUNO, Masaki OKUHARA, Akira OHTA
Chem. Pharm. Bull., 55(10), 1458-1465, 2007年

First ring contraction-desulfurization of 1-(arylcarbonyl)pyrido[2,1-c]-1,4-thiazines to 1-(arylcarbonyl)indolizines and its application to 3-arylthieno[3,2-a]indolizine synthesis
Akikazu KAKEHI, Hiroyuki SUGA, Yuichi GOTO, Nobuhiro YAMAGUCHI
Heterocycles, 74, 521-532, 2007年

Asymmetric cycloaddition reactions between 2-benzopyrylium-4-olates and 3-(2-alkenoyl)-2-oxazolidinones in the presence of 2,6-bis(oxazolinyl)pyridine-lanthanoid complexes
Suga H., Suzuki T., Inoue K., Kakehi A.
Tetrahedron, 62(39), 9218-9225, 2006年09月

Efficient catalytic effects of Lewis acids in the 1,3-dipolar cycloaddition reactions of carbonyl ylides with imines
Suga, H; Ebiura, Y; Fukushima, K; Kakehi, A; Baba, T
JOURNAL OF ORGANIC CHEMISTRY, 70(26), 10782-10791, 2005年

Preparation of new nitrogen-bridged heterocycles. 58. - Syntheses and intramolecular arene-pi interactions of 3-(allylthio)- and 3-(propargylthio)thieno[3,4-b]indolizine derivatives
Kakehi, A; Suga, H; Kaneko, Y; Fujii, T; Tanaka, N
CHEMICAL & PHARMACEUTICAL BULLETIN, 53(11), 1430-1438, 2005年

Highly exo-selective and enantioselective cycloaddition reactions of nitrones catalyzed by a chiral binaphthyidiimine-Ni(II) complex
Suga, H; Nakajima, T; Itoh, K; Kakehi, A
ORGANIC LETTERS, 7(7), 1431-1434, 2005年

Chiral 2,6-bis (oxazolinyl)pyridine-rare earth metal complexes as catalysts for highly enantioselective 1,3-dipolar cycloaddition reactions of 2-benzopyrylium-4-olates
Suga, H; Inoue, K; Inoue, S; Kakehi, A; Shiro, M
JOURNAL OF ORGANIC CHEMISTRY, 70(1), 47-56, 2005年

Syntheses of some 1-(alpha-hydroxybenzyl)thieno[3,4-b]indolizine derivatives and their unexpected condensation reactions
Kakehi, A; Suga, H; Hatayama, S; Kubo, D
Heterocycles, 65(7), 1557-1560, 2005年

Chiral 2,2’-Binaphthyldiimine-nickel(II) Complexes as Lewis Acid Catalysts for Enantioselective Diels-Alder Reactions
Hiroyuki SUGA, Akikazu KAKEHI, Masashi MITSUDA
Bull. Chem. Soc. Jpn., 77(3), 561-568, 2004年03月

Preparation of new nitrogen-bridged heterocycles. 56. Syntheses and reactions of 1-[2,2-bis(alkylthio)-1-(ethoxycarbonylacetyl)vinyl]pyridinium salts
Kakehi, A; Suga, H; Yamauchi, Y; Yasuraoka, K; Kobayashi, T; Ohta, A
CHEMICAL & PHARMACEUTICAL BULLETIN, 52(11), 1316-1321, 2004年

Asymmetric Michael addition reactions of 2-silyloxyfurans catalyzed by binaphthyldiimine-Ni(II) complexes
Suga, H; Kitamura, T; Kakehi, A; Baba, T
Chemical Communications, (12), 1414-1415, 2004年

Preparation of new nitrogen-bridged heterocycles. 55. Reinvestigation of the bromination/dehydrobromination of ethyl 3-[2-(methylthio)indolizin-3-yl]acrylate derivatives
Kakehi, A; Ito, S; Suga, H; Kobayashi, Y; Zuo, P; Iriye, R
CHEMICAL & PHARMACEUTICAL BULLETIN, 52(2), 279-281, 2004年

Stereoselectivity in 1,3-Dipolar Cycloaddtion Reactions of 2-Benzopyrylium-4-olate with Acrylic Acid Derivatives Catalyzed by Rare Earth Metal Triflate
Kei INOUE, Hiroyuki SUGA, Shuichi INOUE, Hiroki SATO, Akikazu KAKEHI
Synthesis, 2003(9), 1413-1418, 2003年09月

Enantio- and Diastereoselectivity in 1,3-Dipolar Cycloaddition Reactions of Nitrones with 3-Crotonoyl-2-oxazolidinone Catalyzed by Ni(II)-Binaphthyldiimine Complexes
Hiroyuki SUGA, Akikazu KAKEHI, Suketaka ITO, and Hiroaki SUGIMOTO
Bull. Chem. Soc. Jpn., 76(2), 327-334, 2003年02月

Asymmetric Cyclopropanation and Aziridination Reactions of Olefins Catalyzed by Cu(I)-Binaphthyldiimine Complexes
Hiroyuki SUGA, Akikazu KAKEHI, Suketaka ITO, Toshikazu IBATA, Tomomi FUDO, Yuzuru WATANABE, Yoshinori KINOSHITA
Bull. Chem. Soc. Jpn., 76(1), 189-199, 2003年01月

Preparation of new nitrogen-bridged heterocycles. 54. Increased arene-arene interactions of 3-(bicyclic and tricyclic arylmethylthio)thieno[3,4-b]indolizine derivatives
Kakehi, A; Suga, H; Kako, T; Fujii, T; Tanaka, N; Kobayashi, T
CHEMICAL & PHARMACEUTICAL BULLETIN, 51(11), 1246-1252, 2003年

Preparation of new nitrogen-bridged heterocycles. 53. Syntheses of 3-(benzylthio)thieno[3,4-b]indolizine derivatives and their intramolecular arene-arene interactions
Kakehi, A; Ito, S; Suga, H; Miwa, T; Mori, T; Fujii, T; Tanaka, N; Kobayashi, T
CHEMICAL & PHARMACEUTICAL BULLETIN, 51(1), 75-84, 2003年

Asymmetric Diels-Alder Reactions Catalyzed by Chiral Ni(II)-Binaphthyldiimine Complexes
Hiroyuki SUGA, Akikazu KAKEHI, Masashi MITSUDA
Chem. Lett., 2002(9), 900-901, 2002年

Highly Enantioselective 1,3-Dipolar Cycloaddition Reactions of 2-Benzopyrylium-4-olate Catalyzed by Chiral Lewis Acids
Hiroyuki SUGA, Kei INOUE, Shuichi INOUE, Akikazu KAKEHI
J. Am. Chem. Soc, 124(50), 14836-14837, 2002年

A through-space interaction of 3-benzylthiothieno[3,4-b]indolizine derivatives combined by a highly flexible spacer
Kakehi, A; Ito, S; Suga, H; Miwa, T; Mori, T; Kobayashi, T
Heterocycles, 57(1), 17-20, 2002年

Regioselectivity in Formal [3 + 2] Cycloaddition Reaction of 5-Alkoxyoxazoles with Diethyl Oxomalonate and 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone
Hiroyuki SUGA, Xiaolan SHI, Toahikazu IBATA, Akikazu KAKEHI
Heterocycles, 55(9), 1711-1725, 2001年

Preparation of new nitrogen-bridged heterocycles. 51. Syntheses and structures of compounds having two indolizine nuclei in a molecule
Kakehi, A; Ito, S; Suga, H; Sakurai, S; Kobayashi, T
CHEMICAL & PHARMACEUTICAL BULLETIN, 49(11), 1401-1405, 2001年

Stereocontrol in a ytterbium triflate-catalyzed 1,3-dipolar cycloaddition reaction of carbonyl ylide with N-substituted maleimides and dimethyl fumarate
Suga, H; Kakehi, A; Ito, S; Inoue, K; Ishida, H; Ibata, T
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 74(6), 1115-1121, 2001年

Preparation of new nitrogen-bridged heterocycles. 50. Syntheses of some heterocyclic compounds starting from pyridinium 1-(ethoxycarbonylacetyl)methylides
Kakehi, A; Ito, S; Suga, H; Yasuraoka, K
Heterocycles, 54(1), 185-200, 2001年

Conformation of Polychloronitrophenyl N-Substituted Morpholines Studied by DNMR and X-Ray Crystal Structure
Xinzhou ZOU, Hiro KUMA, Toshikazu IBATA, Hiroyuki SUGA
J. Chem. Research (S), 265, 2001年

Stereocontrol in rare earth metal triflate-catalyzed 1,3-dipolar cycloaddition reaction of 2-benzopyrylium-4-olate with aldehydes
Suga, H; Kakehi, A; Ito, S; Inoue, K; Ishida, H; Ibata, T
ORGANIC LETTERS, 2(20), 3145-3148, 2000年

Preparation of new nitrogen-bridged heterocycles. 47. Reactions of 2-indolizinethiolates with acetylenic compounds
Kakehi, A; Ito, S; Suga, H; Takahashi, H; Dobashi, K
Heterocycles, 52(1), 215-226, 2000年

Cis and enantioselective synthesis of 2-oxazoline-4-carboxylates through Lewis acid-catalyzed formal [3+2] cycloaddition of 5-alkoxyoxazoles with aldehydes
Suga, H; Ikai, K; Ibata, T
JOURNAL OF ORGANIC CHEMISTRY, 64(19), 7040-7047, 1999年

Lewis acid catalyzed formal [3+2] cycloaddition of 5-alkoxyoxazoles and thiiazoles
Suga, H; Ibata, T
REVIEWS ON HETEROATOM CHEMISTRY, 21, 195-221, 1999年

Total Synthesis of (±)-Quinolizidine 217A
William H. PEARSON, Hiroyuki SUGA
J. Org. Chem., 64(19), 7040-7047, 1998年

Enantioselective Synthesis of cis-2-Oxazoline-4-carboxylates by Lewis Acid Catalyzed Formal [3 + 2] Cycloaddition of 5-Alkoxyoxazoles with Aldehydes
Hiroyuki SUGA, Kosei IKAI, Toshikazu IBATA
Tetrahedron Lett., 39(8), 869-872, 1998年

Preparation of new nitrogen-bridged heterocycles. 46. Selective formation of 4(1H)-8,8a-dihydro-1,4-thiazino[3,4,5-cd]indolizinone and (E)-3-(1,3-oxathiol-2-ylidene)-2(3H)-indolizinone derivatives
Kakehi, A; Ito, S; Suga, H; Kobayashi, T; Hatanaka, S
CHEMICAL & PHARMACEUTICAL BULLETIN, 46(12), 1866-1871, 1998年

Preparation of new nitrogen-bridged heterocycles. 45. Smooth hydrolysis of 6-membered heterocyclic 2-imines with partial aromaticity
Kakehi, A; Ito, S; Suga, H; Takano, S; Hirata, K
CHEMICAL & PHARMACEUTICAL BULLETIN, 46(10), 1632-1634, 1998年

Cu(I)-binaphthyldiimine catalyzed asymmetric cyclopropanation of olefin with diazoacetate
Suga, H; Fudo, T; Ibata, T
Synlett, (8), 933-935, 1998年

Synthesis of 2,5-dihydro-1,2,4-oxadiazoles through formal [3+2] cycloaddition of oxazoles with nitrosobenzene derivatives
Suga, H; Shi, XL; Ibata, T
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 71(5), 1231-1236, 1998年

Stereocontrol of metal-catalyzed cycloaddition of carbonyl ylide with N-substituted maleimide
Suga, H; Ishida, H; Ibata, T
Tetrahedron Letters, 39(20), 3165-3166, 1998年

Regio-Selectivity and Relative Reactivity of Ylide Formation in the Reaction of Ketocarbenoid with Hetero-Cumulenes
Toshikazu IBATA, Motomu HIMORI, Kazuaki FUKUSHIMA, Hiroyuki SUGA, Hirofumi NAKANO
Heterocyclic Commun., 2(1), 87-90, 1996年

Regio-Control of Formal [3 + 2] Cycloadditions of 5-Alkoxyoxazoles with Diethyl Oxomalonate
Hiroyuki SUGA, Xiaolan SHI, Toshikazu IBATA
Chem. Lett., (9), 1673-1676, 1994年

Highly Diastereoselective Synthesis of 2-Oxazoline-4-carboxylates by Formal [3 + 2] Cycloadditions of a 5-Alkoxyoxazole with -Alkoxyaldehydes Catalyzed by Tin(IV) Chloride
Hiroyuki SUGA, Hiroki FUJIEDA, Yoshihiro HIROTSU, Toshikazu IBATA
J. Org. Chem., 59(12), 3359-3364, 1994年

Stereoselective Synthesis of 2-Oxazoline-4-carboxylates through Lewis Acid-Catalyzed Formal [3 + 2] Cycloadditions of 5-Alkoxyoxazoles with Aldehydes
Hiroyuki SUGA, Xiaolan SHI, Toshikazu IBATA
J. Org. Chem., 58(26), 7397-7405, 1993年

Abnormal Diels-Alder Reaction of 5-Alkoxythiazoles with Highly Reactive Dienophiles; 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, Diethyl Azodicarboxylate, and Diethyl Oxomalonate
Xiaolan SHI, Toshikazu IBATA, Hiroyuki SUGA, Kiyoshi MATSUMOTO
Bull. Chem. Soc. Jpn., 65(12), 3315-3321, 1992年

Abnormal Diels-Alder Reaction of Oxazoles with 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione and Diethyl Azodicarboxylate, and X-Ray Crystal Structure of an Adduct
Toshikazu IBATA, Hiroyuki SUGA, Yasushi ISOGAMI, Hatsue TAMURA, Xiaolan SHI
Bull. Chem. Soc. Jpn., 65(11), 2998-3007, 1992年

Abnormal Diels-Alder Reaction of 5-Alkoxyoxazoles with Tetracyanoethylene and X-Ray Crystal Structure of an Adduct
Toshikazu IBATA, Yasushi ISOGAMI, Hiroyuki NAKAWA, Hatsue TAMURA, Hiroyuki SUGA, Xiaolan SHI, Hiroki FUJIEDA
Bull. Chem. Soc. Jpn., 65(11), 1771-1778, 1992年

Reactions of 5-Alkoxyoxazoles with Aldehydes in the Presence of Lewis Acid: Regio- and Stereoselective Formation of 4-Alkoxycarbonyl-2-oxazolines
Hiroyuki SUGA, Xiaolan SHI, Hiroki FUJIEDA, Toshikazu IBATA
Tetrahedron Lett., 32(47), 6911-6914, 1991年

Reaction of Oxazoles with Nitrosobenzene. A Route to 1,2,4-Oxadiazolines
Hiroyuki SUGA, Toshikazu IBATA
Chem. Lett., (7), 1221-1224, 1991年

Acid-Catalyzed Transformation of -Hydroxy--oxo Acetals to -Oxo Esters. A Novel Deconjugation of 4-Oxo-2-alkenal Acetals
Shuji KANEMASA, Norihiko NAKAGAWA, Hiroyuki SUGA, Otohiko TSUGE
Bull. Chem. Soc. Jpn., 62(1), 180-184, 1989年

Synthesis of 4-[(E)-1-Alkenyl]-2-hydroxybutanolides and (Z)-4-Alkylidene-2-butenolides through Cycloadditions Using a Phosphorus-Functionalized Nitrile Oxide
Shuji KANEMASA, Norihiko NAKAGAWA, Hiroyuki SUGA, Otohiko TSUGE
Bull. Chem. Soc. Jpn., 62(1), 171-179, 1989年

Generation of Sulfur-Functionalized Nitrile Oxide, (Phenylthio)acetonitrile Oxide, and Synthetic Applications
Shuji KANEMASA, Yasumasa NORISUE, Hiroyuki SUGA, Otohiko TSUGE
Bull. Chem. Soc. Jpn., 61(11), 3973-3982, 1988年

Synthesis of 2-(1-Phosphorylalkyl)- and 2-(1-Alkenyl)furans through Nitrile Oxide Cycloaddition Route
Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA
Bull. Chem. Soc. Jpn., 61(6), 2133-2146, 1988年

Horner-Emmons Olefination of 4-Hydroxy-2-oxoalkylphosphonates and Related Compounds: Applications to the Syntheses of (±)-Gingerol, (±)-Yashabushiketol, and (±)-Dihydroyashabushiketol
Otohiko TSUGE, Shuji KANEMASA, Norihiko NAKAGAWA, Hiroyuki SUGA
Bull. Chem. Soc. Jpn., 60(11), 4091-4098, 1987年

Synthesis of (Diethoxyphosphoryl)acetonitrile Oxide and Its Cycloaddition to Olefins. Synthetic Applications to 3,5-Disubstituted 2-Isoxazolines
Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA, Norihiko NAKAGAWA
Bull. Chem. Soc. Jpn., 60(7), 2463-2473, 1987年

An Entry to 5-(1-Alkenyl)-3(2H)-furanones through Cycloaddition of Phosphorus-Functionalized Nitrile Oxide to Acetylene Alcohols. An Effective Synthesis of Geiparvarin
Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA
Chem. Lett., (2), 323-326, 1987年

Synthesis of a New Phosphorus-Functionalized Nitrile Oxide, -(Diethylphosphono)acetonitrile Oxide, and Cycloaddition Leading to 3-(Diethylphosphonomethyl)-2-isoxazolines
Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA
Chem. Lett., (2), 183-186, 1986年

A Novel Ring-Opening Reaction of Aziridine Induced by the Formation of Nitrogen-Substituted Carbanion of Nonstabilized Type
Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA, Koyo MATSUDA
Heterocycles, 22(9), 1955-1958, 1984年

Inverse-Electron-Demand 1,3-Dipolar Cycloadditions Using Organocatalysts
Hiroyuki SUGA, Yasunori TODA
Heterocycles, 106, 1649-1686

Methods and Applications of Cycloaddition Reactions in Organic Syntheses
Manabu ABE, Haruyasu ASAHARA, Ramil Y. BAIAZITOV, Scott BUR, Pauline CHIU, Steven D. R. CHRISTIE, Hervé CLAVIER, Jun DENG, Scott E. DENMARK, Francesco De SARLO, James DOUGLAS, Xu-Fei FU, Michael HARMATA, Richard P. HSUNG, Kennosuke ITOH, Darin E. JONES, Akio KAMIMURA, Chitoshi KITAMURA, Kensuke KIYOKAWA, Sarah Y. Y. LAM, Fabrizio MACHETTI, Satoshi MINAKATA, Louis C. MORRILL, *Nagatoshi NISHIWAKI, Albert PADWA, Hélène PELLISSIER, Edward RICHMOND, Andrew D. SMITH, Takahiro SOETA, Hiroyuki SUGA, Ryukichi TAKAGI, Kiyosei TAKASU, Youhei TAKEDA, Osamu TAMURA, Yutaka UKAJI, Hidemitsu UNO, Xiao-Na WANG, Hayley T. A. WATSON, Yosuke YAMAOKA, Zhi-Xiang YU, 共著
John Wiley & Sons, 175-204 2014年

有機立体化学
信州大学

有機化学Ⅱ
信州大学

有機化学演習
信州大学

有機化学実験
信州大学

有機合成化学特論
信州大学

有機合成化学演習
信州大学

有機合成化学特別実験第１
信州大学

有機合成化学特別実験第２
信州大学

一般化学Ⅱ
信州大学

日本化学会

アメリカ化学会

有機合成化学協会

International Society of Heterocyclic Chemestry

有機分子触媒下での逆電子要請型不斉1,3-双極性付加環化反応-方法論の開拓と確立
科学研究費補助金, 基盤研究（C)
2022年 - 2024年

「金属／酸」ハイブリッド触媒系における双極性化合物の立体選択的反応の開発
科学研究費補助金, 基盤研究（C)
2019年 - 2021年

計算化学的スクリーニングを利用した有機分子触媒反応の設計および開発
科学研究費補助金, 基盤研究（C)（特設分野）
2017年 - 2019年

イリド活性化法を基軸とする新規立体選択的分子変換法の開拓と合成化学的応用
科学研究費補助金, 基盤研究（C)
2015年 - 2017年

架橋ヘテロ原子化合物の構築を基盤とする革新的アルカロイド不斉合成法の開拓
科学研究費補助金, 基盤研究（Ｃ）
2012年 - 2014年

キラルルイス酸を触媒とする汎用性不斉双極性付加環化の開発と合成化学的応用
科学研究費補助金, 新学術領域研究
2008年 - 2010年

架橋酸素多環式化合物の汎用性不斉合成法の開拓と合成化学的応用
科学研究費補助金, 基盤研究（Ｃ）
2008年 - 2010年

キラルテクノロジーを用いる触媒的生理活性複素環の合成
科学研究費補助金, 基盤研究（Ｃ）
2005年 - 2006年

キラルルイス酸触媒を用いるカルボニルイリドの不斉付加環化反応の開発
科学研究費補助金, 基盤研究（Ｃ）
2004年

キラルルイス酸を用いるカルボニルイリドの不斉付加環化反応の開発
科学研究費補助金, 基盤研究(C)（一般）
2003年

分子内アセタール誘導体の立体選択的合成とその生理活性に関する研究
受託事業
2002年

軸不斉金属触媒存在下でのジアゾカルボニル化合物を用いる不斉反応の開発
科学研究費補助金, 基盤研究(C)
2000年

軸不斉金属触媒存在下でのジアゾカルボニル化合物を用いる不斉反応の開発
科学研究費補助金, 基盤研究(C)
1999年

オキサゾールとアルデヒド類との反応による2-オキサゾリンの不斉合成
科学研究費補助金, 奨励研究(A)
1995年

オキサゾールおよびチアゾールと電子受容性化合物との反応と合成化学への利用
科学研究費補助金, 奨励研究(A)
1991年

複素芳香族化合物をジエン，親双極子とする超高圧下の周辺環状付加反応
科学研究費補助金, 奨励研究(A)
1989年

複素環化合物の合成及び合成化学的利用

立体選択的反応の開発と合成化学的応用

分子触媒を用いる新規エナンチオ選択的反応の開発

触媒的不斉1,3-双極性付加環化反応の開発