菅 博幸 (スガ ヒロユキ)   

学術研究院(工学系)

工学部 物質化学科 

教授 

学位

  • 工学博士, 九州大学

研究キーワード

    複素環化合物, 付加環化反応, 分子触媒, 合成化学

研究分野

  • 有機合成化学
  • 構造有機化学、物理有機化学, 有機化学

経歴

  • 2006年
    信州大学 教授
  • 1998年
    信州大学 助手
  • 1998年
    信州大学 助教授
  • 1996年
    大阪大学大学院 (理学研究科) 助手
  • 1994年
    大阪大学 (理学部) 助手
  • 1988年
    九州大学 教務員
  • 1988年
    大阪大学 (教養部) 助手

学歴

  • 1996年, ミシガン大学
  • 1988年, 九州大学, 総合理工学研究科
  • 1985年, 九州大学, 総合理工学研究科
  • 1983年, 山口大学, 工学部

論文

  • Ring-fused hexahydro-1,2,4,5-tetrazines: synthesis, structure, and mechanistic studies on isolable rotational isomers
    Yasunori Toda, Airi Kooguchi, Kimiya Sukegawa, Ayaka Kikuchi, Hiroyuki Suga
    Chem. Commun., 59(6), 700-703, 2023年
  • Visible-Light-Driven C-H Imidation of Arenes and Heteroarenes by a Phosphonium Ylide Organophotoredox Catalyst: Application to C-H Functionalization of Alkenes
    Yasunori Toda, Toya Kobayashi, Fumiya Hirai, Takamichi Yano, Makoto Oikawa, Kimiya Sukegawa, Masahiro Shimizu, Fuyuki Ito, Hiroyuki Suga
    J. Org. Chem., 88(13), 9574-9578, 2023年
  • 多機能な分子性触媒を志向したホスホニウムイリドの創製
    戸田泰徳,菅 博幸
    有機合成化学協会誌, 81(4), 333-340, 2023年
  • Asymmetric Cycloadditions of Acyclic Carbonyl Ylides with Aldehydes Catalyzed by a Chiral Binaphthyldiimine-Ni(II) Complex: Enantioselective Synthesis of 1,3-Dioxolanes and Mechanistic Studies by DFT Calculations
    Yasunori Toda, Kayo Sato, Kensuke Sato, Kazuma Nagasaki, Hirotaka Nakajima, Ayaka Kikuchi, Kimiya Sukegawa, Hiroyuki Suga
    Org. Lett., 24(26), 4739-4744, 2022年
  • A phosphonium ylide as a visible light organophotoredox catalyst: A mechanistic study
    Yasunori Toda, Katsumi Tanaka, Riki Matsuda, Tomoyuki Sakamoto, Shiho Katsumi, Masahiro Shimizu, Fuyuki Ito, Hiroyuki Suga
    Chem. Commun., 57(19), 3591-3594, 2021年
  • Enantioselective Protonation of Cyclic Carbonyl Ylides by Chiral Lewis Acid Assisted Alcohols
    Yasunori Toda, Takayuki Yoshida, Kaoru Arisue, Kazuaki Fukushima, Hiroyoshi Esaki, Ayaka Kikuchi, Hiroyuki Suga
    Chem. Eur. J., 27(41), 10578-10582, 2021年
  • Switchable synthesis of cyclic carbamates by carbon dioxide fixation at atmospheric pressure
    Yasunori Toda, Minoru Shishido, Tatsuya Aoki, Kimiya Sukegawa, Hiroyuki Suga
    ROYAL SOC CHEMISTRY, 57(54), 6672-6675, 2021年
  • A phosphonium ylide as a ligand for [3 + 2] coupling reactions of epoxides with heterocumulenes under mild conditions
    Yasunori Toda, Kousuke Hashimoto, Yoko Mori, Hiroyuki Suga
    J. Org. Chem., 85(16), 10980-10987, 2020年
  • Synthesis of 1,2,5-Oxadiazinane Derivatives by Photochemical Cycloaddition of Nitrones with Diaminomethanes
    Kennosuke Itoh, Atsushi Takashino, Atsushi Ohtsuka, Mizuki Kobe, Shunsuke Sawamura, Ryo Kato, Shigeto Hirayama, Fumika Karaki, Takaaki Mizuguchi, Noriko Sato, Ken Tokunaga, Yasunori Toda, Hiroyuki Suga, Hitoshi Ishida, Hideaki Fujii
    CHEMPHOTOCHEM, 4(6), 388-392, 2020年
  • Enantioselective synthesis of 8-azabicyclo[3.2.1]octanes via asymmetric 1,3-dipolar cycloadditions of cyclic azomethine ylides using a dual catalytic system
    Hiroyuki SUGA, Masahiro YOSHIWARA, Takaaki YAMAGUCHI, Takashi BANDO, Mizuki TAGUCHI, Ayano INABA, Yuichi GOTO, Ayaka KiKUCHI, Kennosuke ITOH, Yasunori TODA
    Chem. Commun., 55(11), 1552-1555, 2019年
  • Use of trichloroacetonitrile as a hydrogen chloride generator for ring-opening reactions of aziridines
    Yasunori TODA, Riki MATSUDA, Shuto GOMYOU, Hiroyuki SUGA
    Org. Biomol. Chem., 17(15), 3825-3829, 2019年
  • Novel Asymmetric Photodimerization Reaction of Coumarin Derivatives Bearing a Chiral 2-Oxazolidinone Auxiliary
    Kennosuke ITOH, Fumiya ODATE, Takuma KARIKOMI, Keishi OBE, Tsutomu MIYAMORI, Hideaki KAMIYA, Kenji YOZA, Kenichiro NAGAI, Hideaki FUJII, Hiroyuki SUGA, Ken TOKUNAGA
    RSC Adv., 9(22), 12365-12369, 2019年
  • 4-Hydroxymethyl-substituted oxazolidinone synthesis by tetraarylphosphonium salt-catalyzed reactions of glycidols with isocyanates
    Yasunori TODA, Shoya TANAKA, Shuto GOMYOU, Ayaka KIKUCHI, Hiroyuki SUGA
    Chem. Commun., 55(41), 5761-5764, 2019年
  • Visible-light-triggered Catalytic Halohydrin Synthesis from Epoxides and Trichloroacetonitrile by Copper and Iron Salts
    Yasunori Toda, Katsumi Tanaka, Riki Matsuda, Hiroyuki Suga
    Chem. Lett., 48(12), 1469-1471, 2019年
  • Methoxy Groups Increase Reactivity of Bifunctional Tetraarylphosphonium Salt Catalysts for Carbon Dioxide Fixation: A Mechanistic Study
    Yasunori Toda, Yutaka Komiyama, Hiroyoshi Esaki, Kazuaki Fukushima, Hiroyuki Suga
    J. Org. Chem., 84(23), 15578-15589, 2019年
  • Three-Component Reactions of Diazoesters, Aldehydes, and Imines Using a Dual Catalytic System Consisting of a Rhodium(II) Complex and a Lewis Acid
    Yasunori TODA, Wakatake KAKU, Makoto TSURUOKA, Sho SHINOGAKI, Tomoka ABE, Hideaki KAMIYA, Ayaka KIKUCHI, Kennosuke ITOH, Hiroyuki SUGA
    Org. Lett., 20(9), 2659-2662, 2018年
  • ENANTIOSELECTIVE CYCLOADDITIONS BETWEEN ALIPHATIC NITRILE OXIDES AND 2-HYDROXYSTYRENES CATALYZED BY CHIRAL AMINE-UREA
    Yasunori TODA, Masato KOYAMA, Hiroyoshi ESAKI, Kazuaki FUKUSHIMA, Hiroyuki SUGA
    Heterocycles, 97(1), 147-150, 2018年
  • Lewis Acid Catalysis in Intermolecular [2+2] Photocycloaddition of Coumarin-3-carboxamide Bearing 2-Oxazolidinone Auxiliary with n-Propyl Vinyl Ether and Vinyl Pivalate
    Kennosuke ITOH, Junya MATSUURA, Hideaki KAMIYA, Ryuki KUDO, Yuki TAKAHASHI, Yuta HASHIMOTO, Kenji YOZA, Ken TOKUNAGA, Hideaki FUJII, Hiroyuki SUGA
    Heterocycles, 97(1), 591-603, 2018年
  • Efficient generation of an oxidopyrylium ylide using a Pd catalyst and its [5+2] cycloadditions with several dipolarophiles
    Hiroyuki Suga, Taichi Iwai, Masahiro Shimizu, Kie Takahashi, Yasunori Toda
    Chem. Commun., 54(9), 1109-1112, 2018年WebofScienceリポジトリ電子ジャーナル
  • Triethylamine Enables Catalytic Generation of Oxidopyrylium Ylides for [5+2] Cycloadditions with Alkenes: An Efficient Entry to 8-Oxabicyclo[3.2.1]octane Frameworks
    Yasunori TODA, Masahiro SHIMIZU, Taichi IWAI, Hiroyuki SUGA
    Adv. Synth. Catal., 360(12), 2377-2381, 2018年WebofScienceリポジトリ電子ジャーナル
  • A Phosphonium Ylide as an Ionic Nucleophilic Catalyst for Primary Hydroxyl Group Selective Acylation of Diols
    Yasunori Toda, Tomoyuki Sakamoto, Yutaka Komiyama, Ayaka Kikuchi, Hiroyuki Suga
    ACS Catal., 7(9), 6150-6154, 2017年
  • Tetraarylphosphonium Salt-Catalyzed Synthesis of Oxazolidinones from Isocyanates and Epoxides
    Yasunori Toda, Shuto Gomyou, Shoya Tanaka, Yutaka Komiyama, Ayaka Kikuchi, Hiroyuki Suga
    Org. Lett., 19(21), 5786-5789, 2017年
  • Amine‐Urea‐Mediated Asymmetric Cycloadditions between Nitrile Oxides and o‐Hydroxystyrenes by Dual Activation
    Hiroyuki Suga, Yohei Hashimoto, Yasunori Toda, Kazuaki Fukushima, Hiroyoshi Esaki, Ayaka Kikuchi
    Angew. Chem. Int. Ed., 56(39), 11936-11939, 2017年
  • Tetraarylphosphonium Salt-Catalyzed Carbon Dioxide Fixation at Atmospheric Pressure for the Synthesis of Cyclic Carbonates
    Yasunori Toda, Yutaka Komiyama, Ayaka Kikuchi, and Hiroyuki Suga
    ACS CATALYSIS, 6(10), 6906-6910, 2016年
  • Chiral Lewis Acid-Catalyzed Enantioselective Cycloadditions between Indoles and Cyclic Carbonyl Ylides Derived from Diazodiketone or Diazoketoester Derivatives
    Hiroyuki SUGA, Yurie SEKIKAWA, Shunta MISAWA, Daito KINUGAWA, Rinnosuke ODA, Kennosuke ITOH, Yasunori TODA, Ryotaro KIYONO
    J. Org. Chem., 80(13), 6687-6696, 2015年
  • Photochemically-induced C–C Bond Formation between Tertiary Amines and Nitrones
    Kennosuke ITOH, Ryo KATO, Daito KINUGAWA, Hideaki KAMIYA, Ryuki KUDO, Masayuki HASEGAWA, Hideaki FUJIIA, Hiroyuki SUGA
    Org. Biomol. Chem., 13(33), 8919-8924, 2015年
  • Diastereoselective Synthesis of Tetrahydrofurans by Lewis Acid Catalyzed Intermolecular Carbenoid−Carbonyl Reaction−Cycloaddition Sequences: Unusual Diastereoselectivity of Lewis Acid Catalyzed Cycloadditions
    Yuta HASHIMOTO, Kennosuke ITOH, Akikazu KAKEHI, Motoo SHIRO, Hiroyuki SUGA
    J. Org. Chem., 78(12), 6182-6195, 2013年
  • Chiral Lewis Acid Catalyzed Asymmetric Cycloadditions of Carbonyl Ylides Generated from Diazoimide Derivatives and their Synthetic Applications to Indolizidine Alkaloids
    Hiroyuki SUGA, Yuta HASHIMOTO, Shingo YASUMURA, Ryota TAKEZAWA
    J. Org. Chem., 78(21), 10840-10852, 2013年
  • Molecular Recognition of 2-(Arylmethylthio)indolizine Derivatives Through an Intramolecular Aene-(cation) Interaction
    Akikazu KAKEHI, Kennosuke ITOH, Hiroyuki SUGA, Nobuhiro YAMAGUCHI, Takashi ABE, Yohei YUDA, Haruka KATSUMATA
    Heterocycles, 84(2), 753-764, 2012年
  • Novel Rearrangements of a 8aH-Pyrido[1,2-d]thieno[2’,3’-b][1,4]thiazepine Derivative
    Akikazu KAKEHI, Kennosuke ITOH, Hiroyuki SUGA, Yuuki OHKUBO, Ayaka KOBAYASHI, Takashi NISHI
    Heterocycles, 85(2), 305-312, 2012年
  • A New Synthetic Approch to Some Functionalized Cyclo[3.2.2]azine Derivatives
    Hideyuki MURANAKA, Akikazu KAKEHI, Hiroyuki SUGA, Kennosuke Itoh
    Heterocycles, 82(2), 1251-1266, 2011年
  • Unexpected Formation of Thiino[3’,4’:4,5]oxazolo[1,3-b][1,3]oxazepine Derivatives
    Akikazu KAKEHI, Kennosuke ITOH, Hiroyuki SUGA, Hirofumi KOBAYASHI, Hideyuki MURANAKA
    Heterocycles, 83(3), 1013-1016, 2011年
  • Asymmetric Cycloaddition Reactions of Diazoesters with 2-Alkenoic Acid Derivatives Catalyzed by Binaphthyldiimine Ni(II) complexes
    Hiroyuki Suga, Yasuhisa Furihata, Atsushi Sakamoto, Kennosuke Itoh, Yukihisa Okumura, Teruko Tsuchida, Akikazu Kakehi, Toshihide Baba
    J. Org. Chem., 76(18), 7377–7387, 2011年
  • Synthesis of Spiro[2-cyclopentene-1,3’-imidazo[1,2-a]pyridine] Derivatives and Their Interesting Behavior in 1H-NMR Spectra in Deuteriochloroform
    Abe, T.; Kakehi, A.; Suga, H.; Okumura, Y.; Itoh, K.
    Heterocycles, 81(9), 2075-2086, 2010年09月リポジトリ電子ジャーナル
  • ASYMMETRIC 1,3-DIPOLAR CYCLOADDITION REACTIONS OF AZOMETHINE IMINES WITH ACROLEIN CATALYZED BY L-PROLINE AND ITS DERIVATIVES
    Hiroyuki SUGA, Tadashi ARIKAWA, Kennosuke ITOH, Yukihisa OKUMURA, Akikazu KAKEHI, Motoo SHIRO
    Heterocycles, 81(7), 1669-1688, 2010年07月WebofScienceリポジトリ電子ジャーナル
  • Inverse electron demand asymmetric cycloadditions of cyclic carbonyl ylides catalyzed by chiral Lewis acids-Scope and limitations of diazo and olefinic substrates
    Suga, H; Higuchi, S; Ohtsuka, M; Ishimoto, D; Arikawa, T; Hashimoto, Y; Misawa, S; Tsuchida, T; Kakehi, A; Baba, T
    Tetrahedron, 66(16), 3070-3089, 2010年04月WebofScienceリポジトリ電子ジャーナル
  • A New Approach to Imidazo[1,2-a]pyridine Derivatives and Their Application to the Syntheses of Novel 2H-Pyrano[2’,3’:4,5]imidazo[1,2-a]pyridin-2-one Derivatives
    Abe, T.; Okumura, Y.; Suga, H.; Kakehi, A.
    Heterocycles, 80(1), 439-454, 2010年01月リポジトリ電子ジャーナル
  • PREPARATION OF NEW NITROGEN-BRIDGED HETEROCYCLES. 68. ONE-POT SYNTHSIS OF 4-SUBSTITUTED 5-ACYLTHIENO[3,2-d]THIAZOLE DERIVATIVES
    Kakehi, A; Suga, H; Okumura, Y; Nishi, T
    Heterocycles, 81(1), 175-184, 2010年01月WebofScienceリポジトリ電子ジャーナル
  • Preparation of new nitrogen-bridged heterocycles. 72. A New Approach to 1-Acyl-3-(substituted methylthio)thieno[3',4':4,5]imidazo[1,5-a]pyridine Derivatives
    Akikazu KAKEHI, Hiroyuki SUGA, Yukihisa OKUMURA, Kennosuke ITOH, Kouji KOBAYASHI, Yoshihiro AIKAWA, Kotaro MISAWA
    Chem. Pharm. Bull., 58(11), 1502-1510, 2010年
  • Asymmetric 1,3-Dipolar Cycloaddition Reactions of Nitrile Oxides Catalyzed by Chiral Binaphthyldiimine-Ni(II) Complexes
    Hiroyuki SUGA, Yuki ADACHI, Kouhei FUJIMOTO, Yasuhisa FURIHATA, Teruko TSUCHIDA, Akikazu KAKEHI, Toshihide BABA
    J. Org. Chem., 74(3), 1099-1113, 2009年
  • Preparation of New Nitrogen-bridged Heterocycles 64. A Smooth Formation of 2,4-Diarylpyrido[2,3-b]indolizine-10-carbonitrile Derivatives
    Akikazu KAKEHI, Hiroyuki SUGA, Shuichi SATO
    Heterocycles, 77(1), 471-481, 2009年
  • First Formation of Thiepino[2,3-b]- and Thiepino[3,2-a]indolizine Derivatives
    Hidetoshi ISAWA, Hiroyuki SUGA, Akikazu KAKEHI
    Heterocycles, 78(2), 319-324, 2009年
  • Preparation of New Nitrogen-bridged Heterocycles 67. Syntheses of ,’-Bis-o-, m-, and p-xylene Derivatives and Their Conformational Structures
    Akikazu KAKEHI, Hiroyuki SUGA, Yukihisa OKUMURA, Masatoshi SHINOHARA, Tomonao KAKO, Takeshi SEKIGUCHI, Motoo SHIRO
    Chem. Pharm. Bull., 57(12), 1385-1390, 2009年
  • Reaction of Potassium Pyrazolo[1,5-a]pyridine-2-thiolates with Electron-poor Alkynes
    Hidetoshi ISAWA, Akikazu KAKEHI, Hiroyuki SUGA
    Hetreocyclic Commun., 14(3), 141-148, 2008年
  • Preparation of New Nitrogen-bridged Heterocycles 63. Unexpected Formation of Thieno[3’,4’:4,5]imidazo[1,2-a]pyridines
    Akikazu KAKEHI, Hiroyuki SUGA, Atsushi Izumida, Takashi Abe
    Heterocycles, 76(1), 391-399, 2008年
  • Lewis Acid-Catalyzed Michael Addition Reactions of N-Boc-2-silyloxypyrroles to 3-Acryloyl-2-oxazolidinone
    Suga H., Takemoto H, Kakehi A.
    Heterocycles, 71(2), 361-371, 2007年01月リポジトリ
  • Highly Enantioselective and Diastereoselective 1,3-Dipolar Cycloaddition Reactions between Azomethine Imines and 3-Acryloyl-2-oxazolidinone Catalyzed by Binaphthyldiimine-Ni(II) Complexes
    Hiroyuki SUGA, Akira FUNYU, Akikazu KAKEHI
    Org. Lett., 9(1), 97-100, 2007年
  • Dipole-LUMO/Dipolarophile-HOMO Controlled Asymmetric Cycloadditions of Carbonyl Ylides Catalyzed by Chiral Lewis Acids
    Hiroyuki SUGA, Daisuke ISHIMOTO, Satoshi HIGUCHI, Motoo OHTSUKA
    Org. Lett., 9(21), 4359-4362, 2007年
  • Preparation of New Nitrogen-bridged Heterocycles 59. Syntheses and Intramolecular Interactions of 3-(Acylmethylthio)- and 3-[(3-Ethoxycarbonyl-2-propenyl)thio]thieno[3,4-b]indolizine Derivatives
    Akikazu KAKEHI, Hiroyuki SUGA, Hirohide, ISOGAI
    Chem. Pharm. Bull., 55(1), 95-101, 2007年
  • Syntheses and Conformational Analyses of Bis(indolizin-1-yl) Disulfides
    Akikazu KAKEHI, Hiroyuki SUGA, Hiroko OKUNO, Masaki OKUHARA, Akira OHTA
    Chem. Pharm. Bull., 55(10), 1458-1465, 2007年
  • First ring contraction-desulfurization of 1-(arylcarbonyl)pyrido[2,1-c]-1,4-thiazines to 1-(arylcarbonyl)indolizines and its application to 3-arylthieno[3,2-a]indolizine synthesis
    Akikazu KAKEHI, Hiroyuki SUGA, Yuichi GOTO, Nobuhiro YAMAGUCHI
    Heterocycles, 74, 521-532, 2007年
  • Asymmetric cycloaddition reactions between 2-benzopyrylium-4-olates and 3-(2-alkenoyl)-2-oxazolidinones in the presence of 2,6-bis(oxazolinyl)pyridine-lanthanoid complexes
    Suga H., Suzuki T., Inoue K., Kakehi A.
    Tetrahedron, 62(39), 9218-9225, 2006年09月WebofScienceリポジトリ電子ジャーナル
  • Efficient catalytic effects of Lewis acids in the 1,3-dipolar cycloaddition reactions of carbonyl ylides with imines
    Suga, H; Ebiura, Y; Fukushima, K; Kakehi, A; Baba, T
    JOURNAL OF ORGANIC CHEMISTRY, 70(26), 10782-10791, 2005年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 58. - Syntheses and intramolecular arene-pi interactions of 3-(allylthio)- and 3-(propargylthio)thieno[3,4-b]indolizine derivatives
    Kakehi, A; Suga, H; Kaneko, Y; Fujii, T; Tanaka, N
    CHEMICAL & PHARMACEUTICAL BULLETIN, 53(11), 1430-1438, 2005年WebofScience
  • Highly exo-selective and enantioselective cycloaddition reactions of nitrones catalyzed by a chiral binaphthyidiimine-Ni(II) complex
    Suga, H; Nakajima, T; Itoh, K; Kakehi, A
    ORGANIC LETTERS, 7(7), 1431-1434, 2005年WebofScience
  • Chiral 2,6-bis (oxazolinyl)pyridine-rare earth metal complexes as catalysts for highly enantioselective 1,3-dipolar cycloaddition reactions of 2-benzopyrylium-4-olates
    Suga, H; Inoue, K; Inoue, S; Kakehi, A; Shiro, M
    JOURNAL OF ORGANIC CHEMISTRY, 70(1), 47-56, 2005年WebofScience
  • Syntheses of some 1-(alpha-hydroxybenzyl)thieno[3,4-b]indolizine derivatives and their unexpected condensation reactions
    Kakehi, A; Suga, H; Hatayama, S; Kubo, D
    Heterocycles, 65(7), 1557-1560, 2005年WebofScienceリポジトリ
  • Chiral 2,2’-Binaphthyldiimine-nickel(II) Complexes as Lewis Acid Catalysts for Enantioselective Diels-Alder Reactions
    Hiroyuki SUGA, Akikazu KAKEHI, Masashi MITSUDA
    Bull. Chem. Soc. Jpn., 77(3), 561-568, 2004年03月WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 56. Syntheses and reactions of 1-[2,2-bis(alkylthio)-1-(ethoxycarbonylacetyl)vinyl]pyridinium salts
    Kakehi, A; Suga, H; Yamauchi, Y; Yasuraoka, K; Kobayashi, T; Ohta, A
    CHEMICAL & PHARMACEUTICAL BULLETIN, 52(11), 1316-1321, 2004年WebofScience
  • Asymmetric Michael addition reactions of 2-silyloxyfurans catalyzed by binaphthyldiimine-Ni(II) complexes
    Suga, H; Kitamura, T; Kakehi, A; Baba, T
    Chemical Communications, (12), 1414-1415, 2004年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 55. Reinvestigation of the bromination/dehydrobromination of ethyl 3-[2-(methylthio)indolizin-3-yl]acrylate derivatives
    Kakehi, A; Ito, S; Suga, H; Kobayashi, Y; Zuo, P; Iriye, R
    CHEMICAL & PHARMACEUTICAL BULLETIN, 52(2), 279-281, 2004年WebofScience
  • Stereoselectivity in 1,3-Dipolar Cycloaddtion Reactions of 2-Benzopyrylium-4-olate with Acrylic Acid Derivatives Catalyzed by Rare Earth Metal Triflate
    Kei INOUE, Hiroyuki SUGA, Shuichi INOUE, Hiroki SATO, Akikazu KAKEHI
    Synthesis, 2003(9), 1413-1418, 2003年09月WebofScience
  • Enantio- and Diastereoselectivity in 1,3-Dipolar Cycloaddition Reactions of Nitrones with 3-Crotonoyl-2-oxazolidinone Catalyzed by Ni(II)-Binaphthyldiimine Complexes
    Hiroyuki SUGA, Akikazu KAKEHI, Suketaka ITO, and Hiroaki SUGIMOTO
    Bull. Chem. Soc. Jpn., 76(2), 327-334, 2003年02月WebofScience
  • Asymmetric Cyclopropanation and Aziridination Reactions of Olefins Catalyzed by Cu(I)-Binaphthyldiimine Complexes
    Hiroyuki SUGA, Akikazu KAKEHI, Suketaka ITO, Toshikazu IBATA, Tomomi FUDO, Yuzuru WATANABE, Yoshinori KINOSHITA
    Bull. Chem. Soc. Jpn., 76(1), 189-199, 2003年01月WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 54. Increased arene-arene interactions of 3-(bicyclic and tricyclic arylmethylthio)thieno[3,4-b]indolizine derivatives
    Kakehi, A; Suga, H; Kako, T; Fujii, T; Tanaka, N; Kobayashi, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 51(11), 1246-1252, 2003年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 53. Syntheses of 3-(benzylthio)thieno[3,4-b]indolizine derivatives and their intramolecular arene-arene interactions
    Kakehi, A; Ito, S; Suga, H; Miwa, T; Mori, T; Fujii, T; Tanaka, N; Kobayashi, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 51(1), 75-84, 2003年WebofScience
  • Asymmetric Diels-Alder Reactions Catalyzed by Chiral Ni(II)-Binaphthyldiimine Complexes
    Hiroyuki SUGA, Akikazu KAKEHI, Masashi MITSUDA
    Chem. Lett., 2002(9), 900-901, 2002年WebofScience
  • Highly Enantioselective 1,3-Dipolar Cycloaddition Reactions of 2-Benzopyrylium-4-olate Catalyzed by Chiral Lewis Acids
    Hiroyuki SUGA, Kei INOUE, Shuichi INOUE, Akikazu KAKEHI
    J. Am. Chem. Soc, 124(50), 14836-14837, 2002年WebofScience
  • A through-space interaction of 3-benzylthiothieno[3,4-b]indolizine derivatives combined by a highly flexible spacer
    Kakehi, A; Ito, S; Suga, H; Miwa, T; Mori, T; Kobayashi, T
    Heterocycles, 57(1), 17-20, 2002年WebofScience
  • Regioselectivity in Formal [3 + 2] Cycloaddition Reaction of 5-Alkoxyoxazoles with Diethyl Oxomalonate and 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone
    Hiroyuki SUGA, Xiaolan SHI, Toahikazu IBATA, Akikazu KAKEHI
    Heterocycles, 55(9), 1711-1725, 2001年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 51. Syntheses and structures of compounds having two indolizine nuclei in a molecule
    Kakehi, A; Ito, S; Suga, H; Sakurai, S; Kobayashi, T
    CHEMICAL & PHARMACEUTICAL BULLETIN, 49(11), 1401-1405, 2001年WebofScience
  • Stereocontrol in a ytterbium triflate-catalyzed 1,3-dipolar cycloaddition reaction of carbonyl ylide with N-substituted maleimides and dimethyl fumarate
    Suga, H; Kakehi, A; Ito, S; Inoue, K; Ishida, H; Ibata, T
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 74(6), 1115-1121, 2001年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 50. Syntheses of some heterocyclic compounds starting from pyridinium 1-(ethoxycarbonylacetyl)methylides
    Kakehi, A; Ito, S; Suga, H; Yasuraoka, K
    Heterocycles, 54(1), 185-200, 2001年WebofScience
  • Conformation of Polychloronitrophenyl N-Substituted Morpholines Studied by DNMR and X-Ray Crystal Structure
    Xinzhou ZOU, Hiro KUMA, Toshikazu IBATA, Hiroyuki SUGA
    J. Chem. Research (S), 265, 2001年WebofScience
  • Stereocontrol in rare earth metal triflate-catalyzed 1,3-dipolar cycloaddition reaction of 2-benzopyrylium-4-olate with aldehydes
    Suga, H; Kakehi, A; Ito, S; Inoue, K; Ishida, H; Ibata, T
    ORGANIC LETTERS, 2(20), 3145-3148, 2000年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 47. Reactions of 2-indolizinethiolates with acetylenic compounds
    Kakehi, A; Ito, S; Suga, H; Takahashi, H; Dobashi, K
    Heterocycles, 52(1), 215-226, 2000年WebofScience
  • Cis and enantioselective synthesis of 2-oxazoline-4-carboxylates through Lewis acid-catalyzed formal [3+2] cycloaddition of 5-alkoxyoxazoles with aldehydes
    Suga, H; Ikai, K; Ibata, T
    JOURNAL OF ORGANIC CHEMISTRY, 64(19), 7040-7047, 1999年WebofScience
  • Lewis acid catalyzed formal [3+2] cycloaddition of 5-alkoxyoxazoles and thiiazoles
    Suga, H; Ibata, T
    REVIEWS ON HETEROATOM CHEMISTRY, 21, 195-221, 1999年WebofScience
  • Total Synthesis of (±)-Quinolizidine 217A
    William H. PEARSON, Hiroyuki SUGA
    J. Org. Chem., 64(19), 7040-7047, 1998年
  • Enantioselective Synthesis of cis-2-Oxazoline-4-carboxylates by Lewis Acid Catalyzed Formal [3 + 2] Cycloaddition of 5-Alkoxyoxazoles with Aldehydes
    Hiroyuki SUGA, Kosei IKAI, Toshikazu IBATA
    Tetrahedron Lett., 39(8), 869-872, 1998年
  • Preparation of new nitrogen-bridged heterocycles. 46. Selective formation of 4(1H)-8,8a-dihydro-1,4-thiazino[3,4,5-cd]indolizinone and (E)-3-(1,3-oxathiol-2-ylidene)-2(3H)-indolizinone derivatives
    Kakehi, A; Ito, S; Suga, H; Kobayashi, T; Hatanaka, S
    CHEMICAL & PHARMACEUTICAL BULLETIN, 46(12), 1866-1871, 1998年WebofScience
  • Preparation of new nitrogen-bridged heterocycles. 45. Smooth hydrolysis of 6-membered heterocyclic 2-imines with partial aromaticity
    Kakehi, A; Ito, S; Suga, H; Takano, S; Hirata, K
    CHEMICAL & PHARMACEUTICAL BULLETIN, 46(10), 1632-1634, 1998年WebofScience
  • Cu(I)-binaphthyldiimine catalyzed asymmetric cyclopropanation of olefin with diazoacetate
    Suga, H; Fudo, T; Ibata, T
    Synlett, (8), 933-935, 1998年WebofScience
  • Synthesis of 2,5-dihydro-1,2,4-oxadiazoles through formal [3+2] cycloaddition of oxazoles with nitrosobenzene derivatives
    Suga, H; Shi, XL; Ibata, T
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 71(5), 1231-1236, 1998年WebofScience電子ジャーナル
  • Stereocontrol of metal-catalyzed cycloaddition of carbonyl ylide with N-substituted maleimide
    Suga, H; Ishida, H; Ibata, T
    Tetrahedron Letters, 39(20), 3165-3166, 1998年WebofScience電子ジャーナル
  • Regio-Selectivity and Relative Reactivity of Ylide Formation in the Reaction of Ketocarbenoid with Hetero-Cumulenes
    Toshikazu IBATA, Motomu HIMORI, Kazuaki FUKUSHIMA, Hiroyuki SUGA, Hirofumi NAKANO
    Heterocyclic Commun., 2(1), 87-90, 1996年
  • Regio-Control of Formal [3 + 2] Cycloadditions of 5-Alkoxyoxazoles with Diethyl Oxomalonate
    Hiroyuki SUGA, Xiaolan SHI, Toshikazu IBATA
    Chem. Lett., (9), 1673-1676, 1994年
  • Highly Diastereoselective Synthesis of 2-Oxazoline-4-carboxylates by Formal [3 + 2] Cycloadditions of a 5-Alkoxyoxazole with -Alkoxyaldehydes Catalyzed by Tin(IV) Chloride
    Hiroyuki SUGA, Hiroki FUJIEDA, Yoshihiro HIROTSU, Toshikazu IBATA
    J. Org. Chem., 59(12), 3359-3364, 1994年
  • Stereoselective Synthesis of 2-Oxazoline-4-carboxylates through Lewis Acid-Catalyzed Formal [3 + 2] Cycloadditions of 5-Alkoxyoxazoles with Aldehydes
    Hiroyuki SUGA, Xiaolan SHI, Toshikazu IBATA
    J. Org. Chem., 58(26), 7397-7405, 1993年
  • Abnormal Diels-Alder Reaction of 5-Alkoxythiazoles with Highly Reactive Dienophiles; 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione, Diethyl Azodicarboxylate, and Diethyl Oxomalonate
    Xiaolan SHI, Toshikazu IBATA, Hiroyuki SUGA, Kiyoshi MATSUMOTO
    Bull. Chem. Soc. Jpn., 65(12), 3315-3321, 1992年
  • Abnormal Diels-Alder Reaction of Oxazoles with 4-Phenyl-3H-1,2,4-triazole-3,5(4H)-dione and Diethyl Azodicarboxylate, and X-Ray Crystal Structure of an Adduct
    Toshikazu IBATA, Hiroyuki SUGA, Yasushi ISOGAMI, Hatsue TAMURA, Xiaolan SHI
    Bull. Chem. Soc. Jpn., 65(11), 2998-3007, 1992年
  • Abnormal Diels-Alder Reaction of 5-Alkoxyoxazoles with Tetracyanoethylene and X-Ray Crystal Structure of an Adduct
    Toshikazu IBATA, Yasushi ISOGAMI, Hiroyuki NAKAWA, Hatsue TAMURA, Hiroyuki SUGA, Xiaolan SHI, Hiroki FUJIEDA
    Bull. Chem. Soc. Jpn., 65(11), 1771-1778, 1992年
  • Reactions of 5-Alkoxyoxazoles with Aldehydes in the Presence of Lewis Acid: Regio- and Stereoselective Formation of 4-Alkoxycarbonyl-2-oxazolines
    Hiroyuki SUGA, Xiaolan SHI, Hiroki FUJIEDA, Toshikazu IBATA
    Tetrahedron Lett., 32(47), 6911-6914, 1991年
  • Reaction of Oxazoles with Nitrosobenzene. A Route to 1,2,4-Oxadiazolines
    Hiroyuki SUGA, Toshikazu IBATA
    Chem. Lett., (7), 1221-1224, 1991年
  • Acid-Catalyzed Transformation of -Hydroxy--oxo Acetals to -Oxo Esters. A Novel Deconjugation of 4-Oxo-2-alkenal Acetals
    Shuji KANEMASA, Norihiko NAKAGAWA, Hiroyuki SUGA, Otohiko TSUGE
    Bull. Chem. Soc. Jpn., 62(1), 180-184, 1989年
  • Synthesis of 4-[(E)-1-Alkenyl]-2-hydroxybutanolides and (Z)-4-Alkylidene-2-butenolides through Cycloadditions Using a Phosphorus-Functionalized Nitrile Oxide
    Shuji KANEMASA, Norihiko NAKAGAWA, Hiroyuki SUGA, Otohiko TSUGE
    Bull. Chem. Soc. Jpn., 62(1), 171-179, 1989年
  • Generation of Sulfur-Functionalized Nitrile Oxide, (Phenylthio)acetonitrile Oxide, and Synthetic Applications
    Shuji KANEMASA, Yasumasa NORISUE, Hiroyuki SUGA, Otohiko TSUGE
    Bull. Chem. Soc. Jpn., 61(11), 3973-3982, 1988年
  • Synthesis of 2-(1-Phosphorylalkyl)- and 2-(1-Alkenyl)furans through Nitrile Oxide Cycloaddition Route
    Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA
    Bull. Chem. Soc. Jpn., 61(6), 2133-2146, 1988年
  • Horner-Emmons Olefination of 4-Hydroxy-2-oxoalkylphosphonates and Related Compounds: Applications to the Syntheses of (±)-Gingerol, (±)-Yashabushiketol, and (±)-Dihydroyashabushiketol
    Otohiko TSUGE, Shuji KANEMASA, Norihiko NAKAGAWA, Hiroyuki SUGA
    Bull. Chem. Soc. Jpn., 60(11), 4091-4098, 1987年
  • Synthesis of (Diethoxyphosphoryl)acetonitrile Oxide and Its Cycloaddition to Olefins. Synthetic Applications to 3,5-Disubstituted 2-Isoxazolines
    Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA, Norihiko NAKAGAWA
    Bull. Chem. Soc. Jpn., 60(7), 2463-2473, 1987年
  • An Entry to 5-(1-Alkenyl)-3(2H)-furanones through Cycloaddition of Phosphorus-Functionalized Nitrile Oxide to Acetylene Alcohols. An Effective Synthesis of Geiparvarin
    Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA
    Chem. Lett., (2), 323-326, 1987年
  • Synthesis of a New Phosphorus-Functionalized Nitrile Oxide, -(Diethylphosphono)acetonitrile Oxide, and Cycloaddition Leading to 3-(Diethylphosphonomethyl)-2-isoxazolines
    Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA
    Chem. Lett., (2), 183-186, 1986年
  • A Novel Ring-Opening Reaction of Aziridine Induced by the Formation of Nitrogen-Substituted Carbanion of Nonstabilized Type
    Otohiko TSUGE, Shuji KANEMASA, Hiroyuki SUGA, Koyo MATSUDA
    Heterocycles, 22(9), 1955-1958, 1984年

書籍等出版物

  • Methods and Applications of Cycloaddition Reactions in Organic Syntheses
    Manabu ABE, Haruyasu ASAHARA, Ramil Y. BAIAZITOV, Scott BUR, Pauline CHIU, Steven D. R. CHRISTIE, Hervé CLAVIER, Jun DENG, Scott E. DENMARK, Francesco De SARLO, James DOUGLAS, Xu-Fei FU, Michael HARMATA, Richard P. HSUNG, Kennosuke ITOH, Darin E. JONES, Akio KAMIMURA, Chitoshi KITAMURA, Kensuke KIYOKAWA, Sarah Y. Y. LAM, Fabrizio MACHETTI, Satoshi MINAKATA, Louis C. MORRILL, *Nagatoshi NISHIWAKI, Albert PADWA, Hélène PELLISSIER, Edward RICHMOND, Andrew D. SMITH, Takahiro SOETA, Hiroyuki SUGA, Ryukichi TAKAGI, Kiyosei TAKASU, Youhei TAKEDA, Osamu TAMURA, Yutaka UKAJI, Hidemitsu UNO, Xiao-Na WANG, Hayley T. A. WATSON, Yosuke YAMAOKA, Zhi-Xiang YU, 共著
    John Wiley & Sons, 175-204 2014年

担当経験のある科目_授業

  • 有機立体化学
    信州大学
  • 有機化学Ⅱ
    信州大学
  • 有機化学演習
    信州大学
  • 有機化学実験
    信州大学
  • 有機合成化学特論
    信州大学
  • 有機合成化学演習
    信州大学
  • 有機合成化学特別実験第1
    信州大学
  • 有機合成化学特別実験第2
    信州大学
  • 一般化学Ⅱ
    信州大学

所属学協会

  • 日本化学会
  • アメリカ化学会
  • 有機合成化学協会
  • International Society of Heterocyclic Chemestry

共同研究・競争的資金等の研究課題

  • 「金属/酸」ハイブリッド触媒系における双極性化合物の立体選択的反応の開発
    科学研究費補助金, 基盤研究(C)
    2019年 - 2021年
  • 計算化学的スクリーニングを利用した有機分子触媒反応の設計および開発
    科学研究費補助金, 基盤研究(C)(特設分野)
    2017年 - 2019年
  • イリド活性化法を基軸とする新規立体選択的分子変換法の開拓と合成化学的応用
    科学研究費補助金, 基盤研究(C)
    2015年 - 2017年
  • 架橋ヘテロ原子化合物の構築を基盤とする革新的アルカロイド不斉合成法の開拓
    科学研究費補助金, 基盤研究(C)
    2012年 - 2014年
  • キラルルイス酸を触媒とする汎用性不斉双極性付加環化の開発と合成化学的応用
    科学研究費補助金, 新学術領域研究
    2008年 - 2010年
  • 架橋酸素多環式化合物の汎用性不斉合成法の開拓と合成化学的応用
    科学研究費補助金, 基盤研究(C)
    2008年 - 2010年
  • キラルテクノロジーを用いる触媒的生理活性複素環の合成
    科学研究費補助金, 基盤研究(C)
    2005年 - 2006年
  • キラルルイス酸触媒を用いるカルボニルイリドの不斉付加環化反応の開発
    科学研究費補助金, 基盤研究(C)
    2004年
  • キラルルイス酸を用いるカルボニルイリドの不斉付加環化反応の開発
    科学研究費補助金, 基盤研究(C)(一般)
    2003年
  • 分子内アセタール誘導体の立体選択的合成とその生理活性に関する研究
    受託事業
    2002年
  • 軸不斉金属触媒存在下でのジアゾカルボニル化合物を用いる不斉反応の開発
    科学研究費補助金, 基盤研究(C)
    2000年
  • 軸不斉金属触媒存在下でのジアゾカルボニル化合物を用いる不斉反応の開発
    科学研究費補助金, 基盤研究(C)
    1999年
  • オキサゾールとアルデヒド類との反応による2-オキサゾリンの不斉合成
    科学研究費補助金, 奨励研究(A)
    1995年
  • オキサゾールおよびチアゾールと電子受容性化合物との反応と合成化学への利用
    科学研究費補助金, 奨励研究(A)
    1991年
  • 複素芳香族化合物をジエン,親双極子とする超高圧下の周辺環状付加反応
    科学研究費補助金, 奨励研究(A)
    1989年
  • 複素環化合物の合成及び合成化学的利用
  • 立体選択的反応の開発と合成化学的応用
  • 分子触媒を用いる新規エナンチオ選択的反応の開発
  • 触媒的不斉1,3-双極性付加環化反応の開発