AKIYAMA Yoshiyuki
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
School of Medicine Department of Urology
Professor
Researcher Information
Career
Member History
- 2024 - Present
理事, 日本排尿機能学会 - 2023 - Present
Guidelines Committee Member (Co-Chairman), International Society for the Study of BPS (ESSIC) - 2022 - 2024
監事, 日本排尿機能学会 - 2021 - Present
幹事, 日本間質性膀胱炎研究会 - 2020 - Present
保険委員会/国際委員会 委員, 日本排尿機能学会 - 2020 - 2021
評議員, 日本間質性膀胱炎研究会 - 2018 - Present
間質性膀胱炎/膀胱痛症候群 診療ガイドライン 作成委員 - 2017 - Present
班員, 厚生労働省難治性疾患等政策研究事業研究班 - 2017 - Present
代議員, 日本排尿機能学会
Research activity information
Award
- 2024
IJU Most Cited Article Award of the Year 2022
International academic award - 2023
第110回日本泌尿器科学会総会 International Session Award
International academic award - 2023
IJU Most Cited Article Award of the Year 2021
International academic award - 2021
第109回日本泌尿器科学会総会 総会賞
International academic award - 2020
50th International Continence Society (ICS) annual meeting, BEST IN CATEGORY PRIZE (BEST BASIC SCIENCE)
Autoimmunity to urothelial antigen causes bladder inflammation, pelvic pain and voiding dysfunction: a novel animal model for Hunner type interstitial cystitis, International academic award
Akiyama Y;Lutgendorf S;Kreder K;O’Donnell M;Homma Y;Kume H;Luo Y - 2020
35th Annual EAU Congress of the European Association of Urology, Best Abstract Award (Second Prize for the Best Abstract in Non-Oncology)
Are glomerulations still characteristic marker for interstitial cystitis/bladder pain syndrome? Biological evidences from global gene expression and comprehensive immunohistochemical quantification analyses, International academic award
Yoshiyuki Akiyama - 2018
第106回日本泌尿器科学会総会 総会賞
International academic award
秋山 佳之 - 2017
第105回日本泌尿器科学会総会 総会賞
International academic award
秋山 佳之 - 2017
第26回泌尿器科分子・細胞研究会 研究奨励賞(口演部門)
International academic award
秋山 佳之 - 2016
第23回日本排尿機能学会 河邉賞
International academic award
秋山 佳之 - 2016
46th International Continence Society (ICS) annual meeting. Best Basic Science Abstract Award
International academic award
秋山 佳之 - 2014
44th International Continence Society (ICS) annual meeting. Delegates choice Award for open discussion posters
International academic award
秋山 佳之
Paper
APRIL /BAFF upregulation is associated with clonal B‐cell expansion in Hunner‐type interstitial cystitis
Masafumi Horie; Yoshiyuki Akiyama; Hiroto Katoh; Satoru Taguchi; Masaki Nakamura; Keishi Mizuguchi; Yukinobu Ito; Takashi Matsushita; Tetsuo Ushiku; Shumpei Ishikawa; Akiteru Goto; Haruki Kume; Yukio Homma; Daichi Maeda
The Journal of Pathology, Oct. 2024
Lead- Definition Change and Update of Clinical Guidelines for Interstitial Cystitis and Bladder Pain Syndrome.
Yukio Homma; Yoshiyuki Akiyama; Jang Hwan Kim; Yao-Chi Chuang; Seong Jin Jeong; En Meng; Takeya Kitta; Jia-Fong Jhang; Akira Furuta; Kyu-Sung Lee; Daichi Maeda
Lower urinary tract symptoms, 16(5), e12532, Sep. 2024
Lead - Oncologic and Functional Outcomes of Salvage Robot-Assisted Radical Prostatectomy: Report of the First 10 Cases.
Takahiro Oshina; Yuta Yamada; Tetsuya Fujimura; Satoru Taguchi; Yoshiyuki Akiyama; Jun Kamei; Tomoyuki Kaneko; Taketo Kawai; Daisuke Obinata; Daisuke Yamada; Hiroshi Fukuhara; Tohru Nakagawa; Satoru Takahashi; Haruki Kume
Current oncology (Toronto, Ont.), 31(8), 4762-4768, Aug. 2024
Lead - Novel clipping procedure for preventing post-operative inguinal hernia in robot-assisted radical prostatectomy.
Yuji Hakozaki; Yuta Yamada; Tetsuya Fujimura; Naoki Kimura; Kenichi Sasaki; Kazuki Maki; Kazuma Sugimoto; Taro Izumi; Jun Kaneko; Fumihiko Urabe; Mayuko Tokunaga; Yoichi Fujii; Jun Kamei; Taketo Kawai; Satoru Taguchi; Yoshiyuki Akiyama; Daisuke Yamada; Haruki Kume
International journal of urology : official journal of the Japanese Urological Association, Aug. 2024
Lead - Comparison of PDD-TURBT alone versus white light TURBT plus intravesical BCG therapy: A propensity-score matching study.
Jimpei Miyakawa; Yuta Yamada; Yuji Hakozaki; Katsuhiro Makino; Jun Kamei; Satoru Taguchi; Taketo Kawai; Yoshiyuki Akiyama; Daisuke Yamada; Haruki Kume
Photodiagnosis and photodynamic therapy, 48, 104254-104254, Aug. 2024
Lead - Development of risk-score model in patients with negative surgical margin after robot-assisted radical prostatectomy.
Yuta Yamada; Yoichi Fujii; Shigenori Kakutani; Naoki Kimura; Kazuma Sugimoto; Yuji Hakozaki; Toru Sugihara; Yuta Takeshima; Taketo Kawai; Masaki Nakamura; Jun Kamei; Satoru Taguchi; Yoshiyuki Akiyama; Yusuke Sato; Daisuke Yamada; Fumihiko Urabe; Hideyo Miyazaki; Yutaka Enomoto; Hiroshi Fukuhara; Tohru Nakagawa; Tetsuya Fujimura; Haruki Kume
Scientific reports, 14(1), 7607-7607, Mar. 2024
Lead - 包括的免疫ゲノムプロファイリングによるハンナ型間質性膀胱炎の本態解明(Comprehensive Immunogenomic Profiling of Hunner-type Interstitial Cystitis)
堀江 真史; 秋山 佳之; 加藤 洋人; 水口 敬司; 牛久 哲男; 石川 俊平; 後藤 明輝; 本間 之夫; 前田 大地
日本病理学会会誌, 113(1), 287-287, Feb. 2024
Lead - Efficacy and safety of intravesical dimethyl sulfoxide treatment for patients with refractory Hunner-type interstitial cystitis: Real-world data postofficial approval in Japan.
Yoshiyuki Akiyama; Aya Niimi; Akira Nomiya; Satoru Taguchi; Yuta Yamada; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Haruki Kume; Yukio Homma
International journal of urology : official journal of the Japanese Urological Association, 31(2), 111-118, Feb. 2024
Lead - Six-year outcomes of robot-assisted radical prostatectomy versus volumetric modulated arc therapy for localized prostate cancer: A propensity score-matched analysis.
Michio Noda; Satoru Taguchi; Kenshiro Shiraishi; Tetsuya Fujimura; Akihiro Naito; Taketo Kawai; Jun Kamei; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Tohru Nakagawa; Hideomi Yamashita; Keiichi Nakagawa; Osamu Abe; Hiroshi Fukuhara; Haruki Kume
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], Jan. 2024
Lead - Enfortumab vedotin versus platinum rechallenge in post-platinum, post-pembrolizumab advanced urothelial carcinoma: A multicenter propensity score-matched study.
Satoru Taguchi; Taketo Kawai; Yoshiki Ambe; Kenjiro Kishitani; Kazuma Sugimoto; Jimpei Miyakawa; Yu Nakamura; Michio Noda; Tomoyuki Kaneko; Jun Kamei; Daisuke Obinata; Kenya Yamaguchi; Shigenori Kakutani; Yoshitsune Furuya; Yujiro Sato; Yukari Uemura; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Yutaka Enomoto; Hiroaki Nishimatsu; Tetsuya Fujimura; Hiroshi Fukuhara; Tohru Nakagawa; Satoru Takahashi; Haruki Kume
International journal of urology : official journal of the Japanese Urological Association, 30(12), 1180-1186, Dec. 2023
Lead - Prostate-specific antigen doubling time predicts the efficacy of site-directed therapy for oligoprogressive castration-resistant prostate cancer.
Taketo Kawai; Satoru Taguchi; Keina Nozaki; Naoki Kimura; Takahiro Oshina; Takuya Iwaki; Hotaka Matsui; Aya Niimi; Jun Kamei; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Tomoyuki Kaneko; Subaru Sawayanagi; Hidetsugu Nakayama; Ryogo Minamimoto; Hideomi Yamashita; Hideyo Miyazaki; Tetsuya Fujimura; Tohru Nakagawa; Haruki Kume
Prostate international, 11(4), 239-246, Dec. 2023
Lead - Th1/17 polarization and potential treatment by an anti-interferon-γ DNA aptamer in Hunner-type interstitial cystitis.
Yoshiyuki Akiyama; Kaori Harada; Jimpei Miyakawa; Karl J Kreder; Michael A O'Donnell; Maeda Daichi; Hiroto Katoh; Miyuki Hori; Kensuke Owari; Kazunobu Futami; Shumpei Ishikawa; Tetsuo Ushiku; Haruki Kume; Yukio Homma; Yi Luo
iScience, 26(11), 108262-108262, Nov. 2023
Lead - 膀胱原発composite paraganglioma-ganglioneuromaの一例
秋山 量紀; 山田 雄太; 黒田 亮平; 亀井 潤; 田口 慧; 秋山 佳之; 佐藤 悠佑; 山田 大介; 牛久 哲男; 久米 春喜
日本泌尿器内視鏡・ロボティクス学会総会, 37回, P-4, Nov. 2023
Lead - Efficacy and safety of intravesical dimethyl sulfoxide treatment for patients with refractory Hunner-type interstitial cystitis: Real-world data postofficial approval in Japan.
Yoshiyuki Akiyama; Aya Niimi; Akira Nomiya; Satoru Taguchi; Yuta Yamada; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Haruki Kume; Yukio Homma
International journal of urology : official journal of the Japanese Urological Association, Oct. 2023
Lead - Efficacy and Safety of Low-dose Oral Prednisolone for Patients with Refractory Hunner-type Interstitial Cystitis.
Yoshiyuki Akiyama; Aya Niimi; Akira Nomiya; Satoru Taguchi; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Daichi Maeda; Tetsuo Ushiku; Haruki Kume; Yukio Homma
European urology open science, 56, 1-8, Oct. 2023
Lead - Enfortumab vedotin versus platinum rechallenge in post-platinum, post-pembrolizumab advanced urothelial carcinoma: A multicenter propensity score-matched study.
Satoru Taguchi; Taketo Kawai; Yoshiki Ambe; Kenjiro Kishitani; Kazuma Sugimoto; Jimpei Miyakawa; Yu Nakamura; Michio Noda; Tomoyuki Kaneko; Jun Kamei; Daisuke Obinata; Kenya Yamaguchi; Shigenori Kakutani; Yoshitsune Furuya; Yujiro Sato; Yukari Uemura; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Yutaka Enomoto; Hiroaki Nishimatsu; Tetsuya Fujimura; Hiroshi Fukuhara; Tohru Nakagawa; Satoru Takahashi; Haruki Kume
International journal of urology : official journal of the Japanese Urological Association, Sep. 2023
Lead - Validation of a drug-based score in advanced urothelial carcinoma treated with pembrolizumab.
Satoru Taguchi; Taketo Kawai; Sebastiano Buti; Melissa Bersanelli; Yukari Uemura; Kenjiro Kishitani; Jimpei Miyakawa; Kazuma Sugimoto; Yu Nakamura; Fusako Niimi; Tomoyuki Kaneko; Jun Kamei; Daisuke Obinata; Kenya Yamaguchi; Shigenori Kakutani; Koichiro Kanazawa; Yuriko Sugihara; Mayuko Tokunaga; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Yutaka Enomoto; Hiroaki Nishimatsu; Tetsuya Fujimura; Hiroshi Fukuhara; Tohru Nakagawa; Satoru Takahashi; Haruki Kume
Immunotherapy, 15(11), 827-837, Aug. 2023
Lead - Surgical resection of retinoblastoma-associated bladder leiomyosarcoma during pregnancy: a case report.
Hayato Hoshina; Satoru Taguchi; Hikaru Suyama; Kenjiro Kishitani; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Naoya Akiba; Keiichi Kumasawa; Mayuyo Mori-Uchino; Yutaka Osuga; Haruki Kume
BMC urology, 23(1), 125-125, Jul. 2023
Lead - Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis.
Yoshiyuki Akiyama; Kyuto Sonehara; Daichi Maeda; Hiroto Katoh; Tatsuhiko Naito; Kenichi Yamamoto; Takayuki Morisaki; Shumpei Ishikawa; Tetsuo Ushiku; Haruki Kume; Yukio Homma; Yukinori Okada
Cell reports. Medicine, 4(7), 101114-101114, Jul. 2023
Lead - Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis.
Yoshiyuki Akiyama; Kyuto Sonehara; Daichi Maeda; Hiroto Katoh; Tatsuhiko Naito; Kenichi Yamamoto; Takayuki Morisaki; Shumpei Ishikawa; Tetsuo Ushiku; Haruki Kume; Yukio Homma; Yukinori Okada
Cell reports. Medicine, 4(7), 101114-101114, Jul. 2023
Lead - Genome-wide association study identifies risk loci within the major histocompatibility complex region for Hunner-type interstitial cystitis
Yoshiyuki Akiyama; Kyuto Sonehara; Daichi Maeda; Hiroto Katoh; Tatsuhiko Naito; Kenichi Yamamoto; Biobank Japan Project; Takayuki Morisaki; Shumpei Ishikawa; Tetsuo Ushiku; Haruki Kume; Yukio Homma; Yukinori Okada
Cell Reports Medicine, 4(7), 101114-101114, Jul. 2023, Refereed
Lead - Validation of a drug-based score in advanced urothelial carcinoma treated with pembrolizumab.
Satoru Taguchi; Taketo Kawai; Sebastiano Buti; Melissa Bersanelli; Yukari Uemura; Kenjiro Kishitani; Jimpei Miyakawa; Kazuma Sugimoto; Yu Nakamura; Fusako Niimi; Tomoyuki Kaneko; Jun Kamei; Daisuke Obinata; Kenya Yamaguchi; Shigenori Kakutani; Koichiro Kanazawa; Yuriko Sugihara; Mayuko Tokunaga; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Yutaka Enomoto; Hiroaki Nishimatsu; Tetsuya Fujimura; Hiroshi Fukuhara; Tohru Nakagawa; Satoru Takahashi; Haruki Kume
Immunotherapy, 15(11), 827-837, May 2023
Lead - PSA倍加時間は非転移性もしくはオリゴ転移性去勢抵抗性前立腺癌に対するsite-directed therapyの効果を予測する(PSA doubling time predicts the efficiency of site-directed therapy for non-metastatic or oligometastatic castration-resistant prostate cancer)
川合 剛人; 野崎 圭夏; 田口 慧; 秋山 佳之; 山田 雄太; 佐藤 悠佑; 山田 大介; 新美 文彩; 宮嵜 英世; 南本 亮吾; 山下 英臣; 中川 徹; 久米 春喜
日本泌尿器科学会総会, 110回, AOP05-07, Apr. 2023
Lead - 間質性膀胱炎(ハンナ型)の炎症特性解明と核酸アプタマーを用いた新規治療薬開発(Th1/17 polarization and potential treatment by an anti-interferon-gamma DNA aptamer in Hunner-type interstitial cystitis)
秋山 佳之; Kreder Karl; O'donnell Michael; 宮川 仁平; 前田 大地; 牛久 哲男; 久米 春喜; 本間 之夫; Luo Yi
日本泌尿器科学会総会, 110回, AOP02-02, Apr. 2023
Lead - Subclassification of pT3 upper tract urothelial carcinoma: a multicenter retrospective study.
Yukio Yamada; Tohru Nakagawa; Jimpei Miyakawa; Taketo Kawai; Satoru Taguchi; Mariko Tabata; Tomoyuki Kaneko; Akira Ishikawa; Hideyo Miyazaki; Yasushi Kondo; Akihiko Matsumoto; Akihiro Naito; Masahiro Hikatsu; Yoichi Fujii; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Akira Nomiya; Daisuke Yamada; Taro Murata; Motofumi Suzuki; Yutaka Enomoto; Hiroaki Nishimatsu; Takumi Takeuchi; Yoshinori Tanaka; Haruki Kume
World journal of urology, 41(3), 767-776, Mar. 2023
Lead - Deep Learning Models for Cystoscopic Recognition of Hunner Lesion in Interstitial Cystitis.
Takuya Iwaki; Yoshiyuki Akiyama; Hirokazu Nosato; Manami Kinjo; Aya Niimi; Satoru Taguchi; Yuta Yamada; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Hidenori Sakanashi; Haruki Kume; Yukio Homma; Hiroshi Fukuhara
European urology open science, 49, 44-50, Mar. 2023
Lead - Usefulness of lysophosphatidylcholine measurement in the cerebrospinal fluid for differential diagnosis of neuropathic pain: Possible introduction into clinical laboratory testing.
Makoto Kurano; Masahiko Sumitani; Yoshiyuki Akiyama; Masaki Yamada; Daiki Fujimura; Satoshi Yamaki; Kuniyuki Kano; Junken Aoki; Kentaro Hayakawa; Takuya Takahashi; Takashi Hirai; Atsushi Okawa; Haruki Kume; Toru Ogata; Sakae Tanaka; Hirotaka Chikuda; Yutaka Yatomi
Clinica chimica acta; international journal of clinical chemistry, 541, 117249-117249, Feb. 2023
Lead - Low hemoglobin and PSA kinetics are prognostic factors of overall survival in metastatic castration-resistant prostate cancer patients.
Yuji Hakozaki; Yuta Yamada; Yuta Takeshima; Satoru Taguchi; Taketo Kawai; Masaki Nakamura; Takuya Iwaki; Taro Teshima; Yoshitaka Kinoshita; Yoshiyuki Akiyama; Yusuke Sato; Daisuke Yamada; Motofumi Suzuki; Haruki Kume
Scientific reports, 13(1), 2672-2672, Feb. 2023
Lead - Subclassification of pT3 upper tract urothelial carcinoma: a multicenter retrospective study.
Yukio Yamada; Tohru Nakagawa; Jimpei Miyakawa; Taketo Kawai; Satoru Taguchi; Mariko Tabata; Tomoyuki Kaneko; Akira Ishikawa; Hideyo Miyazaki; Yasushi Kondo; Akihiko Matsumoto; Akihiro Naito; Masahiro Hikatsu; Yoichi Fujii; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Akira Nomiya; Daisuke Yamada; Taro Murata; Motofumi Suzuki; Yutaka Enomoto; Hiroaki Nishimatsu; Takumi Takeuchi; Yoshinori Tanaka; Haruki Kume
World journal of urology, 41(3), 767-776, Feb. 2023
Lead - Cumulative Incidence and Clinical Risk Factors of Radiation Cystitis after Radiotherapy for Prostate Cancer.
Katsuhiro Makino; Yusuke Sato; Ryosuke Takenaka; Hideomi Yamashita; Yoshiyuki Akiyama; Yuta Yamada; Masaki Nakamura; Taketo Kawai; Daisuke Yamada; Motofumi Suzuki; Haruki Kume
Urologia internationalis, 107(5), 440-446, 2023
Lead - Improved survival in real-world patients with advanced urothelial carcinoma: A multicenter propensity score-matched cohort study comparing a period before the introduction of pembrolizumab (2003-2011) and a more recent period (2016-2020).
Satoru Taguchi; Taketo Kawai; Tohru Nakagawa; Jimpei Miyakawa; Kenjiro Kishitani; Kazuma Sugimoto; Yu Nakamura; Jun Kamei; Daisuke Obinata; Kenya Yamaguchi; Tomoyuki Kaneko; Kanae Yoshida; Sachi Yamamoto; Shigenori Kakutani; Koichiro Kanazawa; Yuriko Sugihara; Mayuko Tokunaga; Akihiko Matsumoto; Yukari Uemura; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Yutaka Enomoto; Hiroaki Nishimatsu; Akira Ishikawa; Yoshinori Tanaka; Yasushi Nagase; Tetsuya Fujimura; Hiroshi Fukuhara; Satoru Takahashi; Haruki Kume
International journal of urology : official journal of the Japanese Urological Association, 29(12), 1462-1469, Dec. 2022
Lead - Comparison of full-dose gemcitabine/cisplatin, dose-reduced gemcitabine/cisplatin, and gemcitabine/carboplatin in real-world patients with advanced urothelial carcinoma.
Kazuma Sugimoto; Satoru Taguchi; Kenjiro Kishitani; Taketo Kawai; Kazuki Masuda; Yu Nakamura; Manami Kinjo; Mitsuhiro Tambo; Jimpei Miyakawa; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Tohru Nakagawa; Hiroshi Fukuhara; Haruki Kume
BMC urology, 22(1), 177-177, Nov. 2022
Lead - オリゴ転移にどう対応するか?-手術療法,放射線療法,薬物療法の最適化- PSA倍加時間は非転移性/オリゴ転移性CRPCへのsite-directed therapyの効果を予測する
川合 剛人; 野崎 圭夏; 田口 慧; 秋山 佳之; 山田 雄太; 佐藤 悠佑; 山田 大介; 金子 智之; 新美 文彩; 澤柳 昴; 南本 亮吾; 山下 英臣; 宮嵜 英世; 中川 徹; 久米 春喜
日本癌治療学会学術集会抄録集, 60回, WS7-9, Oct. 2022
Lead - Time to castration resistance is a novel prognostic factor of cancer-specific survival in patients with nonmetastatic castration-resistant prostate cancer.
Yuji Hakozaki; Yuta Yamada; Taketo Kawai; Masaki Nakamura; Yuta Takeshima; Takuya Iwaki; Taro Teshima; Yoshitaka Kinoshita; Yoichi Fujii; Yoshiyuki Akiyama; Yusuke Sato; Daisuke Yamada; Motofumi Suzuki; Mayu Kashiwagi-Hakozaki; Tetsuo Ushiku; Haruki Kume
Scientific reports, 12(1), 16202-16202, Sep. 2022
Lead - Improved survival in real-world patients with advanced urothelial carcinoma: A multicenter propensity score-matched cohort study comparing a period before the introduction of pembrolizumab (2003-2011) and a more recent period (2016-2020).
Satoru Taguchi; Taketo Kawai; Tohru Nakagawa; Jimpei Miyakawa; Kenjiro Kishitani; Kazuma Sugimoto; Yu Nakamura; Jun Kamei; Daisuke Obinata; Kenya Yamaguchi; Tomoyuki Kaneko; Kanae Yoshida; Sachi Yamamoto; Shigenori Kakutani; Koichiro Kanazawa; Yuriko Sugihara; Mayuko Tokunaga; Akihiko Matsumoto; Yukari Uemura; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Yutaka Enomoto; Hiroaki Nishimatsu; Akira Ishikawa; Yoshinori Tanaka; Yasushi Nagase; Tetsuya Fujimura; Hiroshi Fukuhara; Satoru Takahashi; Haruki Kume
International journal of urology : official journal of the Japanese Urological Association, 29(12), 1462-1469, Aug. 2022
Lead - Principal component analysis of early immune cell dynamics during pembrolizumab treatment of advanced urothelial carcinoma.
Taro Teshima; Yukari Kobayashi; Taketo Kawai; Yoshihiro Kushihara; Koji Nagaoka; Jimpei Miyakawa; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Nobuyuki Tanaka; Tatsuhiko Tsunoda; Haruki Kume; Kazuhiro Kakimi
Oncology letters, 24(2), 265-265, Aug. 2022
Lead - The 'prostate-muscle index': a simple pelvic cavity measurement predicting estimated blood loss and console time in robot-assisted radical prostatectomy.
Naoki Kimura; Yuta Yamada; Yuta Takeshima; Masafumi Otsuka; Nobuhiko Akamatsu; Yuji Hakozaki; Jimpei Miyakawa; Yusuke Sato; Yoshiyuki Akiyama; Daisuke Yamada; Tetsuya Fujimura; Haruki Kume
Scientific reports, 12(1), 11945-11945, Jul. 2022
Lead - 精巣癌の自覚症状の出現から高位精巣摘除術までの期間と臨床病理学的因子の検討
白鳥 太一; 川合 剛人; 田口 慧; 皆川 英之; 本多 一貴; 中村 雄; 金子 智之; 秋山 佳之; 山田 雄太; 佐藤 悠佑; 山田 大介; 福原 浩; 中川 徹; 久米 春喜
泌尿器外科, 35(臨増), 834-834, Jul. 2022
Lead - 精巣癌の自覚症状の出現から高位精巣摘除術までの期間と臨床病理学的因子の検討
白鳥 太一; 川合 剛人; 田口 慧; 皆川 英之; 本多 一貴; 中村 雄; 金子 智之; 秋山 佳之; 山田 雄太; 佐藤 悠佑; 山田 大介; 福原 浩; 中川 徹; 久米 春喜
泌尿器外科, 35(臨増), 834-834, Jul. 2022
Lead - Cumulative Incidence and Clinical Risk Factors of Radiation Cystitis after Radiotherapy for Prostate Cancer.
Katsuhiro Makino; Yusuke Sato; Ryosuke Takenaka; Hideomi Yamashita; Yoshiyuki Akiyama; Yuta Yamada; Masaki Nakamura; Taketo Kawai; Daisuke Yamada; Motofumi Suzuki; Haruki Kume
Urologia internationalis, 107(5), 1-7, Mar. 2022
Lead - A case of miliary tuberculosis following transurethral surgery and prostate biopsy after intravesical Bacillus Calmette–Guerin immunotherapy
Yoshiaki Kurokawa; Taketo Kawai; Jimpei Miyakawa; Naohiro Makise; Yoshiyuki Akiyama; Yuta Yamada; Yusuke Sato; Daisuke Yamada; Tetsuo Ushiku; Haruki Kume
IJU Case Reports, 5(1), 45-47, Jan. 2022
Lead - The association between the parameters of uroflowmetry and lower urinary tract symptoms in prostate cancer patients after robot-assisted radical prostatectomy.
Yuta Takeshima; Yuta Yamada; Kotaro Takemura; Naoki Kimura; Yuji Hakozaki; Jimpei Miyakawa; Satoru Taguchi; Yoshiyuki Akiyama; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Tetsuya Fujimura; Haruki Kume
PloS one, 17(10), e0275069, 2022
Lead - Early recurrence of bladder cancer in the colon after robot-assisted radical cystectomy: Disappearance following dose-dense methotrexate, vinblastine, doxorubicin and cisplatin treatment.
Michio Noda; Masaki Nakamura; Taketo Kawai; Yusuke Sato; Yuta Yamada; Yoshiyuki Akiyama; Daisuke Yamada; Motofumi Suzuki; Haruki Kume
IJU case reports, 4(6), 429-432, Nov. 2021
Lead - Cystectomy for patients with Hunner-type interstitial cystitis at a tertiary referral center in Japan.
Yoshiyuki Akiyama; Aya Niimi; Yasuhiko Igawa; Akira Nomiya; Yuta Yamada; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Haruki Kume; Yukio Homma
Lower urinary tract symptoms, 14(2), 102-108, Oct. 2021
Lead - Overexpression of HIF1α in Hunner Lesions of Interstitial Cystitis: Pathophysiological Implications.
Yoshiyuki Akiyama; Jimpei Miyakawa; Michael A O'Donnell; Karl J Kreder; Yi Luo; Daichi Maeda; Tetsuo Ushiku; Haruki Kume; Yukio Homma
The Journal of urology, 207(3), 101097JU0000000000002278-646, Oct. 2021
Lead - 精巣癌自覚症状出現から高位精巣摘除術までの期間と精巣癌進行 多施設共同後向き研究
白鳥 太一; 川合 剛人; 田口 慧; 皆川 英之; 本多 一貴; 中村 雄; 金子 智之; 秋山 佳之; 山田 雄太; 佐藤 悠佑; 山田 大介; 福原 浩; 中川 徹; 久米 春喜
日本癌治療学会学術集会抄録集, 59回, O59-1, Oct. 2021
Lead - 精巣癌自覚症状出現から高位精巣摘除術までの期間と精巣癌進行 多施設共同後向き研究
白鳥 太一; 川合 剛人; 田口 慧; 皆川 英之; 本多 一貴; 中村 雄; 金子 智之; 秋山 佳之; 山田 雄太; 佐藤 悠佑; 山田 大介; 福原 浩; 中川 徹; 久米 春喜
日本癌治療学会学術集会抄録集, 59回, O59-1, Oct. 2021
Lead - Clinicopathological features and oncological outcomes of urothelial carcinoma involving the ureterovesical junction.
Takahiro Oshina; Satoru Taguchi; Jimpei Miyakawa; Yoshiyuki Akiyama; Yusuke Sato; Taketo Kawai; Hiroshi Fukuhara; Tohru Nakagawa; Haruki Kume
Japanese journal of clinical oncology, 52(1), 65-72, Sep. 2021
Lead - Editorial Comment from Dr Akiyama to Decreased urothelial cytoskeleton and cell proliferation protein expression suggest interstitial cystitis/bladder pain syndrome patients with Hunner's lesion and grade 3 glomerulation might be different from other types of patients.
Yoshiyuki Akiyama
International journal of urology : official journal of the Japanese Urological Association, 28(8), 831-831, Aug. 2021
Lead - Clinical significance and risk factors of International Society of Urological Pathology (ISUP) grade upgrading in prostate cancer patients undergoing robot-assisted radical prostatectomy.
Yuta Takeshima; Yuta Yamada; Taro Teshima; Tetsuya Fujimura; Shigenori Kakutani; Yuji Hakozaki; Naoki Kimura; Yoshiyuki Akiyama; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Haruki Kume
BMC cancer, 21(1), 501-501, May 2021
Lead - Clinical significance and risk factors of urethrovesical anastomotic urinary leakage following robot-assisted radical prostatectomy: a multi-institutional study.
Shigenori Kakutani; Yuta Takeshima; Yuta Yamada; Tetsuya Fujimura; Shoichi Nagamoto; Yutaka Enomoto; Yuji Hakozaki; Naoki Kimura; Taro Teshima; Yoshiyuki Akiyama; Yusuke Sato; Taketo Kawai; Daisuke Yamada; Haruki Kume
BMC urology, 21(1), 75-75, May 2021
Lead - Efficacy and safety of intravesical instillation of KRP-116D (50% dimethyl sulfoxide solution) for interstitial cystitis/bladder pain syndrome in Japanese patients: A multicenter, randomized, double-blind, placebo-controlled, clinical study.
Naoki Yoshimura; Yukio Homma; Hikaru Tomoe; Atsushi Otsuka; Takeya Kitta; Naoya Masumori; Yoshiyuki Akiyama; Aya Niimi; Takahiko Mitsui; Masaharu Nanri; Takashige Namima; Mineo Takei; Akito Yamaguchi; Yuki Sekiguchi; Mitsuru Kajiwara; Shinya Kobayashi; Kaname Ameda; Yozo Ohashi; Sadaaki Sakamoto; Osamu Muraki; Toshihide Shishido; Shinji Kageyama; Koji Kokura; Homare Okazoe; Tomonori Yamanishi; Toyohiko Watanabe; Takashi Uno; Akira Ohinata; Tomohiro Ueda
International journal of urology : official journal of the Japanese Urological Association, 28(5), 545-553, May 2021
Lead - Impact of Initial Computed Tomography Findings on Management of Atypical Urinary Cytology of the Upper Urinary Tract.
Kotaro Takemura; Taketo Kawai; Yusuke Sato; Jimpei Miyakawa; Satoru Taguchi; Yoshiyuki Akiyama; Yuta Yamada; Masaki Nakamura; Daisuke Yamada; Motofumi Suzuki; Tohru Nakagawa; Haruki Kume
Urologia internationalis, 105(7-8), 1-5, Jan. 2021
Lead - Relationship between the frequency of electrocautery of Hunner lesions and changes in bladder capacity in patients with Hunner type interstitial cystitis.
Yoshiyuki Akiyama; Masayoshi Zaitsu; Daiji Watanabe; Itsuki Yoshimura; Aya Niimi; Akira Nomiya; Yuta Yamada; Yusuke Sato; Masaki Nakamura; Taketo Kawai; Daisuke Yamada; Motofumi Suzuki; Haruki Kume; Yukio Homma
Scientific reports, 11(1), 105-105, Jan. 2021
Lead - Impact of age, body mass index, and renal function for severe hypotension caused by oral 5-aminolevulinic acid administration in patients undergoing transurethral resection of bladder tumor.
Jimpei Miyakawa; Taketo Kawai; Katsuhiro Makino; Yoshiyuki Akiyama; Yuta Yamada; Masaki Nakamura; Yusuke Sato; Daisuke Yamada; Motofumi Suzuki; Haruki Kume
Photodiagnosis and photodynamic therapy, 33, 102179-102179, Jan. 2021
Lead - Clinical characterization of interstitial cystitis/bladder pain syndrome in women based on the presence or absence of Hunner lesions and glomerulations.
Daiji Watanabe; Yoshiyuki Akiyama; Aya Niimi; Akira Nomiya; Yuta Yamada; Yusuke Sato; Masaki Nakamura; Taketo Kawai; Daisuke Yamada; Motofumi Suzuki; Yasuhiko Igawa; Haruki Kume; Yukio Homma
Lower urinary tract symptoms, 13(1), 139-143, Jan. 2021
Lead - Autoimmunity to urothelial antigen causes bladder inflammation, pelvic pain and voiding dysfunction: a novel animal model for Hunner type interstitial cystitis.
Yoshiyuki Akiyama; Jian-Rong Yao; Karl J Kreder; Michael A O'Donnell; Susan K Lutgendorf; Dan Lyu; Daichi Maeda; Haruki Kume; Yukio Homma; Yi Luo
American journal of physiology. Renal physiology, 320(2), F174-F182, Dec. 2020
Lead - A Fatal Case of Myocarditis Following Myositis Induced by Pembrolizumab Treatment for Metastatic Upper Urinary Tract Urothelial Carcinoma.
Hotaka Matsui; Taketo Kawai; Yusuke Sato; Junichi Ishida; Hiroshi Kadowaki; Yoshiyuki Akiyama; Yuta Yamada; Masaki Nakamura; Daisuke Yamada; Hiroshi Akazawa; Motofumi Suzuki; Issei Komuro; Haruki Kume
International heart journal, 61(5), 1070-1074, Sep. 2020
Lead - Inverted papilloma of the urinary bladder shows fluorescence on photodynamic diagnosis using 5-aminolevulinic acid.
Takahiro Oshina; Taketo Kawai; Yusuke Sato; Jimpei Miyakawa; Yu Miyama; Katsuhiro Makino; Yoshiyuki Akiyama; Yuta Yamada; Masaki Nakamura; Daisuke Yamada; Motofumi Suzuki; Tetsuo Ushiku; Haruki Kume
Photodiagnosis and photodynamic therapy, 30, 101766-101766, Jun. 2020, Refereed, Not invited
Lead - Clinical guidelines for interstitial cystitis/bladder pain syndrome
Yukio Homma; Yoshiyuki Akiyama; Hikaru Tomoe; Akira Furuta; Tomohiro Ueda; Daichi Maeda; Alex TL Lin; Hann-Chorng Kuo; Ming-Huei Lee; Seung-June Oh; Joon Chul Kim; Kyu-Sung Lee
International Journal of Urology, 27(7), 578-589, Apr. 2020, Refereed, Not invited
Lead - Update on the pathophysiology of interstitial cystitis/bladder pain syndrome. Current Bladder Dysfunction Reports.
Yoshiyuki Akiyama
Current Bladder Dysfunction Reports, 15, 1-8, Jan. 2020, Refereed, Invited
Lead, Corresponding - Classification, Characterization, and Sub-Grouping of Interstitial Cystitis
Homma Y, Akiyama Y, Niimi A, Nomiya A, Igawa Y
Current Bladder Dysfunction Reports, 14, 294-300, Nov. 2019, Refereed, Invited
Lead - Molecular Taxonomy of Interstitial Cystitis/Bladder Pain Syndrome Based on Whole Transcriptome Profiling by Next-Generation RNA Sequencing of Bladder Mucosal Biopsies.
Yoshiyuki Akiyama; Daichi Maeda; Hiroto Katoh; Teppei Morikawa; Aya Niimi; Akira Nomiya; Yusuke Sato; Taketo Kawai; Akiteru Goto; Tetsuya Fujimura; Hiroshi Fukuhara; Tohru Nakagawa; Yasuhiko Igawa; Shumpei Ishikawa; Masashi Fukayama; Haruki Kume; Yukio Homma
The Journal of urology, 202(2), 290-300, Aug. 2019, Refereed, Not invited
Lead - ロボット支援下膀胱全摘除術の初期経験
中村 真樹; 山田 大介; 松井 甫雄; 秋山 佳之; 木下 善隆; 手島 太郎; 佐藤 悠佑; 川合 剛人; 野田 軌夫; 藤村 哲也; 久米 春喜
日本泌尿器科学会総会, 107回, PP2-116, Apr. 2019, Refereed, Not invited
Lead - ロボット支援下根治的前立腺全摘除術後のcontinence recoveryと膀胱造影検査所見との関連の検討
塩澤 迪夫; 秋山 佳之; 川合 剛人; 山田 大介; 松本 明彦; 藤村 哲也; 福原 浩; 久米 春喜
日本泌尿器科学会総会, 106回, OP-011, Apr. 2018, Refereed, Not invited
Lead - Extent of Hunner lesions: The relationships with symptom severity and clinical parameters in Hunner type interstitial cystitis patients
Yoshiyuki Akiyama; Aya Niimi; Akira Nomiya; Yukio Yamada; Tohru Nakagawa; Tetsuya Fujimura; Hiroshi Fukuhara; Haruki Kume; Yasuhiko Igawa; Yukio Homma
Neurourology and Urodynamics, 37(4), 1441-1447, Apr. 2018, Refereed, Not invited
Lead - Diagnostic value of urinary CXCL10 as a biomarker for predicting Hunner type interstitial cystitis.
Aya Niimi; Yasuhiko Igawa; Naoki Aizawa; Toshiki Honma; Akira Nomiya; Yoshiyuki Akiyama; Jun Kamei; Tetsuya Fujimura; Hiroshi Fukuhara; Yukio Homma
Neurourology and urodynamics, 37(3), 1113-1119, Mar. 2018, Refereed, Not invited
Lead - Digital quantitative analysis of mast cell infiltration in interstitial cystitis
Yoshiyuki Akiyama; Daichi Maeda; Teppei Morikawa; Aya Niimi; Akira Nomiya; Yukio Yamada; Yasuhiko Igawa; Akiteru Goto; Masashi Fukayama; Yukio Homma
Neurourology and Urodynamics, 37(2), 650-657, Feb. 2018, Refereed, Not invited
Lead - 膀胱用超音波診断装置Liliumα-200による定時膀胱容量測定の妥当性 ビデオウロダイナミクス検査との比較検討
亀井 潤; 秋山 佳之; 渡邉 大仁; 松井 甫雄; 藤村 哲也; 福原 浩; 井川 靖彦
日本排尿機能学会誌, 28(1), 242-242, Sep. 2017
Lead - Toll-like receptor 7 is overexpressed in the bladder of Hunner-type interstitial cystitis, and its activation in the mouse bladder can induce cystitis and bladder pain
Koji Ichihara; Naoki Aizawa; Yoshiyuki Akiyama; Jun Kamei; Naoya Masumori; Karl-Erik Andersson; Yukio Homma; Yasuhiko Igawa
PAIN, 158(8), 1538-1545, Aug. 2017, Refereed, Not invited
Lead - Increased CXCR3 Expression of Infiltrating Plasma Cells in Hunner Type Interstitial Cystitis
Yoshiyuki Akiyama; Teppei Morikawa; Daichi Maeda; Yukako Shintani; Aya Niimi; Akira Nomiya; Atsuhito Nakayama; Yasuhiko Igawa; Masashi Fukayama; Yukio Homma
SCIENTIFIC REPORTS, 6, 28652-28652, Jun. 2016, Refereed, Not invited
Lead - FREQUENT EXPANSION OF CLONAL B-CELLS SUGGESTIVE OF SPECIFIC IMMUNE RESPONSES IN HUNNER TYPE INTERSTITIAL CYSTITIS
Yoshiyuki Akiyama; Daichi Maeda; Teppei Morikawa; Akira Nomiya; Yukio Yamada; Jun Kamei; Naoki Aizawa; Yasuhiko Lgawa; Masashi Fukayama; Yukio Homma
JOURNAL OF UROLOGY, 195(4), E952-E952, Apr. 2016, Refereed, Not invited
Lead - Hunner-Type (Classic) Interstitial Cystitis: A Distinct Inflammatory Disorder Characterized by Pancystitis, with Frequent Expansion of Clonal B-Cells and Epithelial Denudation
Daichi Maeda; Yoshiyuki Akiyama; Teppei Morikawa; Akiko Kunita; Yasunori Ota; Hiroto Katoh; Aya Niimi; Akira Nomiya; Shumpei Ishikawa; Akiteru Goto; Yasuhiko Igawa; Masashi Fukayama; Yukio Homma
PLOS ONE, 10(11), e0143316, Nov. 2015, Refereed, Not invited
Lead - Video-urodynamic effects of mirabegron, a (3)-adrenoceptor agonist, in patients with low-compliance bladder
Jun Kamei; Akira Furuta; Yoshiyuki Akiyama; Aya Niimi; Koji Ichihara; Tetsuya Fujimura; Hiroshi Fukuhara; Haruki Kume; Yukio Homma; Yasuhiko Igawa
INTERNATIONAL JOURNAL OF UROLOGY, 22(10), 956-961, Oct. 2015, Refereed, Not invited
Lead - Botulinum toxin typeA injection for refractory interstitial cystitis: A randomized comparative study and predictors of treatment response
Yoshiyuki Akiyama; Akira Nomiya; Aya Niimi; Yukio Yamada; Tetsuya Fujimura; Tohru Nakagawa; Hiroshi Fukuhara; Haruki Kume; Yasuhiko Igawa; Yukio Homma
INTERNATIONAL JOURNAL OF UROLOGY, 22(9), 835-841, Sep. 2015, Refereed, Not invited
Lead - PREVENTIVE EFFECTS OF CALORIC RESTRICTION ON AGING-ASSOCIATED BIOLOGICAL AND MOLECULAR CHANGES IN THE RAT BLADDER AND DORSAL ROOT GANGLIA
Hiroki Ito; Naoki Aizawa; Rino Sugiyama; Jun Kamei; Yoshiyuki Akiyama; Koji Ichihara; Yasunori Fujita; Toshio Kojima; Yukio Homma; Yoshinobu Kubota; Masafumi Ito; Karl-Erik Andersson; Yasuhiko Igawa
JOURNAL OF UROLOGY, 193(4), E75-E75, Apr. 2015, Refereed, Not invited
Lead - FUNCTIONAL CHANGES OF THE BLADDER IN VIVO IN MICE LACKING TRANSIENT RECEPTOR POTENTIAL MELASTAIN 2 (TRPM2) CHANNELS
Jun Kamei; Naoki Aizawa; Takayuki Nakagawa; Hiroki Ito; Rino Sugiyama; Yoshiyuki Akiyama; Koji Ichihara; Shuji Kaneko; Yukio Homma; Yasuhiko Igawa
JOURNAL OF UROLOGY, 193(4), E128-E129, Apr. 2015, Refereed, Not invited
Lead
MISC
- 間質性膀胱炎における拡張後粘膜出血の診断的意義 網羅的遺伝子発現/組織定量解析法による検討
秋山 佳之; 新美 文彩; 野宮 明; 渡辺 大仁; 久米 春喜; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 29(1), 275 - 275, Sep. 2018, Not invited
Lead - 間質性膀胱炎とその類縁疾患における臨床像の比較
渡邉 大仁; 秋山 佳之; 野宮 明; 新美 文彩; 相澤 直樹; 久米 春喜; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 29(1), 278 - 278, Sep. 2018, Not invited
Lead - ハンナ型間質性膀胱炎に対する神経障害性疼痛関連物質であるリゾリン脂質の関与
新美 文彩; 竹村 光太郎; 山田 幸央; 亀井 潤; 秋山 佳之; 野宮 明; 井川 靖彦; 本間 之夫
日本泌尿器科学会総会, 106回, OP - 418, Apr. 2018, Not invited
Lead - ハンナ型間質性膀胱炎に対する神経障害性疼痛関連物質であるリゾリン脂質の関与
新美 文彩; 竹村 光太郎; 山田 幸央; 亀井 潤; 秋山 佳之; 野宮 明; 井川 靖彦; 本間 之夫
日本泌尿器科学会総会, 106回, OP - 418, Apr. 2018, Not invited
Lead - 間質性膀胱炎に対するヘパリンとヘパリン・リドカインカクテルによる膀胱内注入療法の無作為化二重盲検並行群間比較試験
野宮 明; 田畑 真梨子; 新美 文彩; 秋山 佳之; 榎本 裕; 福原 浩; 井川 靖彦; 本間 之夫; 久米 春喜
日本泌尿器科学会総会, 106回, OP - 545, Apr. 2018, Not invited
Lead - ハンナ型間質性膀胱炎に対する神経障害性疼痛関連物質であるリゾフォスファチジルコリンの関与
新美 文彩; 山田 幸央; 竹村 光太郎; 野宮 明; 秋山 佳之; 亀井 潤; 相澤 直樹; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 28(1), 187 - 187, Sep. 2017, Not invited
Lead - 間質性膀胱炎患者における細菌性膀胱炎に関する検討
野宮 明; 田畑 真梨子; 山本 幸; 本田 圭; 依田 憲治; 亀井 潤; 秋山 佳之; 新美 文彩; 飯田 勝之; 榎本 裕; 井川 靖彦; 本間 之夫
日本泌尿器科学会総会, 105回, OP09 - 7, Apr. 2017, Not invited
Lead - 頻尿を伴う炎症性膀胱痛に対するTransient receptor potential(TRP) M2およびTRPA1チャネルの役割 ノックアウトマウスを用いたLPS膀胱内注入による検討
亀井 潤; 相澤 直樹; 中川 貴之; 秋山 佳之; 金子 周司; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 27(1), 177 - 177, Dec. 2016, Not invited
Lead - 間質性膀胱炎粘膜におけるTRPC1、4発現の検討
野宮 明; 新美 文彩; 秋山 佳之; 亀井 潤; 藤村 哲也; 福原 浩; 榎本 裕; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 27(1), 217 - 217, Dec. 2016, Not invited
Lead - 間質性膀胱炎の経過中に低容量膀胱となった症例の臨床的検討
新美 文彩; 秋山 佳之; 亀井 潤; 野宮 明; 山田 幸央; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 27(1), 219 - 219, Dec. 2016, Not invited
Lead - 肥満細胞浸潤は真に間質性膀胱炎に特徴的な所見か? 組織定量解析法による検証
秋山 佳之; 前田 大地; 新美 文彩; 野宮 明; 山田 幸央; 後藤 明輝; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 27(1), 216 - 216, Dec. 2016, Not invited
Lead - 間質性膀胱炎生検検体における肥満細胞浸潤の意義
前田 大地; 秋山 佳之; 後藤 明輝
日本病理学会会誌, 105(1), 432 - 432, Apr. 2016, Not invited
Lead - 雄性下部尿路閉塞ラットにおける膀胱伸展受容一次求心性神経活動の解析 膀胱微小収縮との関連性の検討
杉山 梨乃; 相澤 直樹; 伊藤 悠城; 亀井 潤; 秋山 佳之; 市原 浩司; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 26(1), 138 - 138, Sep. 2015, Not invited
Lead - β3作動薬ミラベグロンは低コンプライアンス膀胱に対してビデオウロダイナミクス所見を改善する
亀井 潤; 古田 昭; 秋山 佳之; 新美 文彩; 市原 浩司; 藤村 哲也; 福原 浩; 久米 春喜; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 26(1), 141 - 141, Sep. 2015, Not invited
Lead - Toll-like receptor(TLR)7の活性化はマウスにおいて頻尿・膀胱痛・膀胱炎を惹起しうる
市原 浩司; 相澤 直樹; 杉山 梨乃; 伊藤 悠城; 亀井 潤; 秋山 佳之; 舛森 直哉; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 26(1), 213 - 213, Sep. 2015, Not invited
Lead - ラット膀胱伸展受容一次求心性神経のAδおよびC線維の活動性に及ぼすresiniferatoxin脱感作の直接作用
相澤 直樹; 伊藤 悠城; 杉山 梨乃; 亀井 潤; 秋山 佳之; 市原 浩司; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 26(1), 216 - 216, Sep. 2015, Not invited
Lead - ハンナ型間質性膀胱炎の一部はB細胞のクローナル増殖を伴う慢性炎症・免疫疾患群である
秋山 佳之; 前田 大地; 森川 鉄平; 新美 文彩; 野宮 明; 山田 幸央; 相澤 直樹; 杉山 梨乃; 亀井 潤; 伊藤 悠城; 市原 浩司; 藤村 哲也; 中川 徹; 福原 浩; 久米 春喜; 井川 靖彦; 深山 正久; 本間 之夫
日本排尿機能学会誌, 26(1), 219 - 219, Sep. 2015, Not invited
Lead - CHARACTERIZATION OF THE MECHANOSENSITIVE BLADDER AFFERENT ACTIVITIES IN RELATION WITH MICROCONTRACTIONS IN MALE RATS WITH BLADDER OUTLET OBSTRUCTION
R. Sugiyama; N. Aizawa; H. Ito; J. Kamei; Y. Akiyama; K. Ichihara; H. Fukuhara; Y. Homma; Y. Igawa
NEUROUROLOGY AND URODYNAMICS, 34, S435 - S437, Aug. 2015, Not invited
Lead - 除脳マウスにおいてToll like receptor(TLR)7刺激薬イミキモドの膀胱内注入は頻尿を誘発する
市原 浩司; 相澤 直樹; 杉山 梨乃; 伊藤 悠城; 亀井 潤; 秋山 佳之; 舛森 直哉; 本間 之夫; 井川 靖彦
日本泌尿器科学会総会, 103回, 477 - 477, Apr. 2015, Not invited
Lead - 加齢に伴うラット排尿動態の変化と長期カロリー制限による予防効果 排尿行動測定(FV測定)および膀胱内圧測定(CMG)による検討
亀井 潤; 伊藤 悠城; 相澤 直樹; 杉山 梨乃; 秋山 佳之; 市原 浩司; 藤田 泰典; 伊藤 雅史; 本間 之夫; 井川 靖彦
日本泌尿器科学会総会, 103回, 552 - 552, Apr. 2015, Not invited
Lead - B-cell異常に着目した間質性膀胱炎の病理組織学的研究
前田 大地; 秋山 佳之; 森川 鉄平; 後藤 明輝; 深山 正久
日本病理学会会誌, 104(1), 276 - 276, Mar. 2015, Not invited
Lead - ラット膀胱の加齢性収縮能減弱とそれに対する長期カロリー制限による予防効果の背景因子の検討 脂質酸化ストレスおよび線維化の関与
伊藤 悠城; 相澤 直樹; 杉山 梨乃; 亀井 潤; 秋山 佳之; 鈴木 基文; 市原 浩司; 小島 俊男; 藤田 泰典; 伊藤 雅史; 本間 之夫; 窪田 吉信; 井川 靖彦
日本排尿機能学会誌, 25(1), 149 - 149, Sep. 2014, Not invited
Lead - Transient receptor potential melastatin 2(TRPM2)チャネルの膀胱機能調節における生理的意義 ノックアウトマウスを用いた機能解析
亀井 潤; 相澤 直樹; 中川 貴之; 伊藤 悠城; 杉山 梨乃; 秋山 佳之; 市原 浩司; 新美 文彩; 金子 周司; 藤村 哲也; 鈴木 基文; 福原 浩; 久米 春喜; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 25(1), 150 - 150, Sep. 2014, Not invited
Lead - ラット膀胱伸展受容一次求心性神経のC線維の活動性に対する膀胱ムスカリン受容体の促進的寄与
相澤 直樹; 伊藤 悠城; 杉山 梨乃; 亀井 潤; 秋山 佳之; 市原 浩司; 藤村 哲也; 鈴木 基文; 福原 浩; 久米 春喜; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 25(1), 177 - 177, Sep. 2014, Not invited
Lead - ラット膀胱伸展受容求心性神経活動制御における膀胱アドレナリンα1D受容体の生理的役割
相澤 直樹; 伊藤 悠城; 杉山 梨乃; 亀井 潤; 秋山 佳之; 市原 浩司; 藤村 哲也; 鈴木 基文; 福原 浩; 久米 春喜; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 25(1), 177 - 177, Sep. 2014, Not invited
Lead - ハンナ型間質性膀胱炎と非ハンナ型間質性膀胱炎は別の病態か Tissue Studioを用いた病理組織の定量的解析
秋山 佳之; 前田 大地; 山田 幸央; 新美 文彩; 野宮 明; 亀井 潤; 相澤 直樹; 鈴木 基文; 藤村 哲也; 中川 徹; 福原 浩; 久米 春喜; 井川 靖彦; 深山 正久; 本間 之夫
日本排尿機能学会誌, 25(1), 180 - 180, Sep. 2014, Not invited
Lead - 膀胱出口部閉塞後亜急性期の雄性ラットの尿流動態に対するTRPA1およびTRPV1チャネルの関与
杉山 梨乃; 相澤 直樹; 伊藤 悠城; 亀井 潤; 秋山 佳之; 市原 浩司; 藤村 哲也; 鈴木 基文; 福原 浩; 久米 春喜; 本間 之夫; 井川 靖彦
日本排尿機能学会誌, 25(1), 199 - 199, Sep. 2014, Not invited
Lead - 難治性間質性膀胱炎に対するボツリヌス毒素膀胱壁内注入療法の効果予測因子の検討 当院における無作為化比較試験結果から
秋山 佳之; 野宮 明; 新美 文彩; 山田 幸央; 亀井 潤; 鈴木 基文; 藤村 哲也; 中川 徹; 福原 浩; 久米 春喜; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 25(1), 212 - 212, Sep. 2014, Not invited
Lead - ハンナ病変凝固術の効果持続期間に影響を与える因子の検討
新美 文彩; 山田 幸央; 野宮 明; 秋山 佳之; 亀井 潤; 藤村 哲也; 井川 靖彦; 本間 之夫
日本排尿機能学会誌, 25(1), 263 - 263, Sep. 2014, Not invited
Lead - ベータ3作動薬ミラベグロンの低コンプライアンス膀胱に対する有効性の検討
亀井 潤; 古田 昭; 新美 文彩; 秋山 佳之; 吉田 美香子; 鈴木 基文; 藤村 哲也; 久米 春喜; 真田 弘美; 井川 靖彦; 本間 之夫
日本泌尿器科学会総会, 102回, 567 - 567, Apr. 2014, Not invited
Lead
Books and other publications
- 今日の治療指針
秋山 佳之, Joint work, 副腎腫瘍
医学書院, 2019泌尿器外科
秋山 佳之, Joint work, 泌尿器慢性疾患の生活指導:間質性膀胱炎患者の生活指導
医学図書出版, 2018排尿障害プラクティス
秋山 佳之, Joint work, 受賞演題・論文解説
メディカルレビュー社, 2018別冊BIO Clinica 泌尿器系疾患と慢性炎症
秋山 佳之, Joint work, 間質性膀胱炎について
北隆館, 2018泌尿器ケア
秋山 佳之, Joint work, 下部尿路機能障害の治療とケア:間質性膀胱炎の病態と治療
メディカ出版, 2017排尿障害プラクティス Cutting Edge
秋山 佳之, Joint work, ICS2016 PRIZE AWARD
2017泌尿器外科:後期研修医がおさえておきたい泌尿器疾患TOP30
秋山 佳之, Joint work, 間質性膀胱炎
2017Urology Today
秋山 佳之, Joint work, 間質性膀胱炎の疾患概念の転換
2017腎臓内科・泌尿器科
秋山 佳之, Joint work
科学評論社, 2017泌尿器ケア:過活動膀胱の診断・治療とケア
秋山 佳之, Single work, 過活動膀胱の薬物療法
メディカ出版, 2014日本医師会雑誌
秋山 佳之, Joint work, 高齢社会における下部尿路障害:過活動膀胱の行動療法と薬物療法
日本医師会, 2014Research Themes
- Development of a novel murine model and potential treatment by a DNA aptamer in Hunner-type interstitial cystitis and
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Early-Career Scientists
The University of Tokyo
01 Apr. 2022 - 31 Mar. 2025 - Fluorescent Substrates for Cancer Detection Using Clinical Specimens and Animal Models Aiming for Negative Margin of Prostate Cancer Surgery
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
The University of Tokyo
01 Apr. 2021 - 31 Mar. 2026 - 尿路上皮における遺伝子変異の蓄積と癌化のメカニズムの解明
科学研究費助成事業, 日本学術振興会, 基盤研究(C)
東京大学
01 Apr. 2021 - 31 Mar. 2024 - 全ゲノム関連解析によるハンナ型間質性膀胱炎の疾患感受性遺伝子と新規治療標的の探索
科学研究費助成事業 若手研究, 文部科学省
Apr. 2019 - Mar. 2022 - 髄液中リゾリン脂質測定の客観的疼痛マーカーとしての臨床検査への導入
日本医療研究開発機構研究費, 国立研究開発法人日本医療研究開発機構
Apr. 2019 - 間質性膀胱炎の難治性疼痛における疼痛関連分子であるリゾリン脂質の関与
科学研究費助成事業 基盤研究(C), 文部科学省
Apr. 2018 - Mar. 2021 - 間質性膀胱炎の患者登録と診療ガイドラインに関する研究
厚生労働科学研究費補助金, 厚生労働省
Apr. 2018 - Mar. 2020 - 免疫ゲノムプロファイリングによるハンナ型間質性膀胱炎の病態解明研究
平成29年度医学研究奨励助成, 難病医学研究財団
Apr. 2017 - Mar. 2018 - 免疫性炎症と尿路上皮剥離の遺伝学的変化探索によるハンナ型間質性膀胱炎の病態解明
科学研究費助成事業 研究活動スタート支援, 文部科学省
2017 - 2018 - ゲノム病態解析を基軸としたハンナ型間質性膀胱炎の診断精度向上と新規治療法開発に関する研究
日本医療研究開発機構研究費, 国立研究開発法人日本医療研究開発機構
Apr. 2016 - Mar. 2019 - ゲノム病理学的アプローチによる間質性膀胱炎の病態解明
第16回 Asahi Kasei Pharma Urological Academy研究助成
Apr. 2016 - Mar. 2017