EHARA TAKASHI

School of Medicine Department of Pathology 

Professor 

Degree

  • 博士(医学), 信州大学

Research Keyword

    Glomerulonephritis

Field Of Study

  • Human pathology
  • Experimental pathology

Educational Background

  • 1991 - 1992, University of Alabama at Birmingham
  • 1981 - 1986, 信州大学, 医学部, 病理
  • 1975 - 1981, 信州大学, 医学部, 医学科
Research activity information

Award

  • 2004
    信州医学会, 信州医学会賞
  • 1994
    松医会, 松医会賞

Paper

  • Collagenofibrotic Glomerulopathy
    Miyake M, Katayama K, Ehara T, Sado Y, Nawa S, Murata T, Mizutani Y, Joh K, Ito M, Dohi K.
    Intern Med., 60(6), 911-915, Mar. 2021
  • An autopsy case of amyloid tubulopathy exhibiting characteristic spheroid-type deposition
    chimata S, Hata Y, Abe R, Yoshinaga T, Katoh N, Kametani F, Yazaki M, Sekijima Y, Ehara T, Nishida N.
    Virchows Arch., 477(1), 157-163, Jul. 2020
  • Fibrillary glomerulopqathy with a high level of myeloperoxidase-ANCA: A case report
    Asakawa T, Ehara T
    Case reports in Nephrology, 2020
  • AL-Kappa primary amyloidosis with apolipoprotein A-IV deposition
    Intern Med., 61, 871-876, 2020
  • Tranilast modulates fibrosis,epithelial-mesenchymal transition and peritubular capillary injuries in unilateral ureteral obstruction rats
    Kaneyama T, Kobayashi S, Aoyagi D, Ehara T
    PATHOLOGY, 42(6), 564-573, 2010
  • Trypsin digestion on paraffin sections is a useful tool for diagnosis of Alport syndrome
    Jiang YS, Ehara T
    Ultrastructural Pathology, 34(4), 199-206, 2010
  • Comparison of the histological and immunohistochemical features of the thymus in young- and elderly-onset myasthenia gravis without thymoma
    Ishii, W; Matsuda, M; Hanyuda, M; Momose, M; Nakayama, J; Ehara, T; Ikeda, S
    JOURNAL OF CLINICAL NEUROSCIENCE, 14(2), 110-115, 2007WebofScienceリポジトリ電子ジャーナル
  • Mitochondrial complex I activity is significantly decreased in a patient with maternally inherited type 2 diabetes mellitus and hypertrophic cardiomyopathy associated with mitochondrial DNA C3310T mutation: A cybrid study
    Chen, J; Hattori, Y; Nakajima, K; Eizawa, T; Ehara, T; Koyama, M; Hirai, T; Fukuda, Y; Kinoshita, M; Sugiyama, A; Hayashi, JI; Onaya, T; Kobayashi, T; Tawata, M
    DIABETES RESEARCH AND CLINICAL PRACTICE, 74(2), 148-153, 2006WebofScience
  • Rapid demonstration of diversity of sulfatide molecular species from biological materials by MALDI-TOF MS
    Kyogashima, M; Tamiya-Koizumi, K; Ehara, T; Li, G; Hu, R; Hara, A; Aoyama, T; Kannagi, R
    GLYCOBIOLOGY, 16(8), 719-728, 2006WebofScience
  • Ethnicity affects the diagnostic validity of alpha-fetoprotein in hepatocellular carcinoma
    Gad A, Tanaka E, Matsumoto A, Serwah Ael-H , Attia F , Hassan A, Ali K , Abbas A, el-Deeb Ael- , Sun X, Umemura T, Ichijyo T, Ehara T, Yoshizawa K, Kiyosawa K
    Asia-Pacific Journal of clinical oncology, 1, 64-70, 2005
  • 最近の腎臓病学の進歩とあゆみ
    江原孝史
    信州医学雑誌, 53, 365-379, 2005
  • 直腸原発malignant rhabdoid tumor の1例
    中山 中,辻本和雄,伊藤憲雄,竹内信道,松下昌充,江原孝史
    日本消化器外科学会雑誌, 38, 1630-1635, 2005
  • Decreased distribution of nitric oxide synthase and vasoactive intestinal polypeptide positive nerve cells in the sphincter of Oddi in humans with pancreatobiliary diseases
    Zhang M, Shimojo H, Ehara T, Shigematsu H
    Arch Histol Cytol, 68(2), 121-131, 2005WebofScience
  • A heteroplasmic mitochondrial DNA 3310 mutation in the ND1 gene in a patient with type 2 diabetes, hypertrophic cardiomyopathy, and mental retardation
    Hattori Y, Takeoka M, Nakajima K, Ehara T, Koyama M
    Exp Clin Endocr Diab, 113(6), 318-323, 2005WebofScience
  • Immunohistochemical detection of immunoglobulins and complements in formaldehyde-fixed and paraffin-embedded renal biopsy tissues: an adjunct for diagnosis of glomerulonephritis
    Chowdhury AKM, Ehara T, Higuchi M, Hora K, Shigematsu H
    Nephrology, 10(3), 298-304, 2005WebofScience
  • Renal cholesterol embolism: Analysis of two spontaneous autopsy cases
    Ehara T, Yazawa M, Konishi K, Hora K, Shigematsu H
    Nephrology, 10(1), 90-96, 2005WebofScience
  • 最近の腎臓病学の進歩とあゆみ : Slit diaphragmと糸球体腎炎を中心に
    江原孝史
    信州医学雑誌, 53(6), 365-379, 2005リポジトリ
  • 穿刺吸引細胞診で推測しえた甲状腺硝子化索状腺腫の1例
    半田幸雄,中村ひさ子,小嶋紀子,草間 律,江原孝史
    日本臨床細胞学会雑誌, 43, 281-285, 2004
  • 肥満細胞と腎障害
    江原孝史,重松秀一
    腎と透析, 57, 410-418, 2004
  • MPO-ANCA, PR3-ANCA, 抗GBM抗体陽性の肺腎症候群の1剖検例
    村木真紀子,出浦 正,徳永真一,渡辺正秀,江原孝史,重松秀一,洞 和彦,清沢研道
    腎と透析, 57, 130-133, 2004
  • Calponin h1 expression in renal tumor vessels: correlations with multiple pathological factors of renal cell carcinoma
    Islam AH, Ehara T, Kato H, Hayama M, Kobayashi S, Igawa Y, Nishizawa O
    J Urol, 171(3), 1319-1323, 2004WebofScience
  • Angiomyolipoma of kidney involving the inferior vena cava
    Islam AH, Ehara T, Kato H, Hayama M, Kashiwabara T, Nishizawa O
    Int J Urol, 11(10), 897-902, 2004WebofScience
  • Loss of calponin h1 in renal angiomyolipoma correlates with aggressive clinical behavior
    Islam AH, Ehara T, Kato H, Hayama M, Nishizawa O
    Urology, 64(3), 468-473, 2004WebofScience
  • 尿細管間質病変の病理
    江原孝史,重松秀一
    腎と透析, 55, 429-437, 2003
  • 尿細管間質性病変を呈した腎生検例の検討-1990年から2002年までの53例について
    江原孝史,小口智雄,下条久志,重松秀一
    信州医学雑誌, 51, 411-418, 2003
  • Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter
    Takeda T, Inaba H, Yamazaki M, Kyo S, Miyamoto T, Suzuki S, Ehara T,Kakizawa T, Hara M, DeGroot LJ, Hashizume K
    J Clin Endoclinol Metab, 88(8), 3531-3538, 2003WebofScience
  • Younger onset myeloperoxidase-specific antineutrophil cytoplasmic antibody-(MPO-ANCA) related glomerulonephritis accompanied with nephrotic syndrome
    Kaneko Y, Kamijo Y, Kobayashi N, Higuchi M, Ehara T, Hora K, Shigematsu S, Kiyosawa K
    Clin Nephrol, 60(4), 275-278, 2003WebofScience
  • Reduced expression of actin-binding proteins, h-caldesmon and calponin h1, in the vascular smooth muscle inside melanoma lesions: an adverse prognostic factor for malignant melanoma
    Koganehira Y, Takeoka M, Ehara T, Sasaki K, Murata H, Saida T, Taniguchi S
    British J Dermatology, 148(5), 971-980, 2003WebofScience
  • Heteroplasmic mitochondrial DNA 3310 mutation in NADH dehydrogenase subunit 1 associated with type 2 diabetes, hypertrophic cardiomyopathy, and mental retardation in a single patient
    Hattori Y, Nakajima K, Eizawa T, Ehara T, Koyama M, Hirai T, Fukuda Y, Kinoshita M
    Diabetes Care, 26(3), 952-953, 2003WebofScience
  • Mast cells in the kidney
    Ehara T, Shigematsu H
    Nephrology, 8(3), 130-138, 2003WebofScience
  • Structural and phenotypic changes of podocyte in puromycin aminonucleosisde and protamine sulfate intermittent treated rat model.
    Ichikawa, T; Shimojo, H; Kaneko, Y; Kamijo, Y; Higuchi, M; Hora, K; Kiyosawa, K; Otani, M; Ehara, T; Shigematsu, H
    Journal of the American Society of Nephrology, 14, 155A-155A, 2003WebofScience
  • A study of IgA nephropathy cases with minor glomerular abnormalities and nephrotic syndrome
    Ehara T,Shigematsu H
    Nephrology, 7, A102, 2002
  • 腎生検で診断し得たコレステロール塞栓症の2例-腎組織に出現した炎症細胞についての検討-
    江原孝史,上條祐司,金子洋子,中沢功,重松秀一
    信州医学雑誌, 50, 361-369, 2002
  • Calponin h1 suppresses tumor growth of src-induced transformed 3Y1 cells in association with a decrease in angiogenesis
    Kaneko M, Takeoka M, Oguchi M, Koganehira Y, Murata H, Ehara T, Tozuka M, Saida T, Taniguchi S
    Jpn J Cancer Res, 93(8), 935-943, 2002WebofScience
  • A case of mixed membranous nephropathy and purpura nephritis
    Ehara T, Muramatsu T, Shigematsu H
    Clin Nephrol, 57(6), 480-483, 2002WebofScience
  • A case of an ABO-incompatible renal transplant with abundant intratubular basement membrane immune deposits
    Shiozawa S, Ichikawa T, Nakazawa K, Ehara T, Shigematsu H
    Clin Transplant, 16, 68-71, 2002WebofScience
  • Calponin H1 induced a flattened morphology and suppressed the growth of human fibrosasrcoma HT1080 cells
    Takeoka M, Ehara T, Hashimoto S, Taniguchi S
    Eur J Cancer, 38(3), 436-442, 2002WebofScience
  • Structural fragility of blood vessels and peritoneum in calponin h1-deficient mice, resulting in an increase in hematogenous metastasis and peritoneal dissemination of malignant tumor cells
    Taniguchi, S; Takeoka, M; Ehara, T; Hashimoto, S; Shibuki, H; Yoshimura, N; Shigematsu, H; Takahashi, K; Katsuki, M
    CANCER RESEARCH, 61(20), 7627-7634, 2001WebofScience
  • Close relation of reduced expression of actin-binding proteins, calponin-h1 and h-caldesmon, in the vascular smooth muscle inside human malignant melanoma with the poor prognosis
    Koganehira, Y; Takeoka, T; Ehara, T; Hashimoto, S; Murata, H; Saida, T; Taniguchi, S
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 117(2), 393-393, 2001WebofScience
  • CyA-mediated renal interstitial and vascular lesions in the rat under low-sodium diet
    Nagasawa, T; Ehara, T
    TOXICOLOGIC PATHOLOGY, 28(4), 518-528, 2000WebofScience
  • Nodular lung disease with five year survival and unilateral pleural effusion in AL amyloidosis
    Ikeda, S; Takabayashi, Y; Maejima, Y; Tachibana, N; Ehara, T; Nezu, A; Hoshii, Y
    AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION, 6(4), 292-296, 1999WebofScience
  • Reduced expression of an actin binding protein, calponin h 1 (CNh1), in blood vessels of human malignant skin tumors
    Koganehira, Y; Ehara, T; Takeoka, M; Saida, T; Taniguchi, S
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 112(4), 569-569, 1999WebofScience
  • Promoted dermal fibrosis during wound healing in calponin h 1 (CNhl)-deleted mice
    Takeoka, M; Ehara, T; Murata, H; Saida, T; Katsuki, M; Takahashi, K; Taniguchi, S
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 112(4), 583-583, 1999WebofScience
  • Contribution of mast cells to the tubulointerstitial lesions in IgA nephritis
    Ehara, T; Shigematsu, H
    KIDNEY INTERNATIONAL, 54(5), 1675-1683, 1998WebofScience電子ジャーナル
  • BASEMENT-MEMBRANE CHONDROITIN SULFATE PROTEOGLYCAN ALTERATIONS IN A RAT MODEL OF POLYCYSTIC KIDNEY-DISEASE
    EHARA, T; CARONE, FA; MCCARTHY, KJ; COUCHMAN, JR
    AMERICAN JOURNAL OF PATHOLOGY, 144(3), 612-621, 1994WebofScience
  • HIGH-RESOLUTION ULTRASOUND OF THE CHEST-WALL
    SAKAI, F; SONE, S; KIYONO, K; IMAI, S; IZUNO, I; OGUCHI, M; OKAZAKI, Y; KASUGA, T; EHARA, T
    FORTSCHRITTE AUF DEM GEBIETE DER RONTGENSTRAHLEN UND DER NEUEN BILDGEBENDEN VERFAHREN, 153(4), 390-394, 1990WebofScience
  • CHARACTERIZATION OF GLYCOCONJUGATES FOUND IN GRANULAR-CELL TUMORS, WITH SPECIAL REFERENCE TO KERATAN SULFATE
    EHARA, T; KATSUYAMA, T
    VIRCHOWS ARCHIV B-CELL PATHOLOGY INCLUDING MOLECULAR PATHOLOGY, 58(3), 221-227, 1990WebofScience

Affiliated academic society

  • 日本腎臓学会
  • 日本癌学会
  • 日本臨床細胞学会
  • 日本細胞生物学会
  • 日本小児科学会
  • International Acedemy of pathology
  • International Society of Nephrology

Research Themes

  • IL. 1beta, IL. 18を活性化するASCを標的とした関節リウマチ治療実験
    科学研究費補助金, 基盤研究(C)
    2009 - 2010
  • 進行性腎障害に関する調査研究
    厚生労働省科学研究費助成金
    2008 - 2010
  • 病気の教育方法についての研究(バーチャル病気博物館の作成)
    科学研究費補助金, 基盤研究(C)
    2005 - 2006
  • 腎線維化