平林 耕一 (ヒラバヤシ コウイチ)
学術研究院（医学系（附属病院））
医学部附属病院 小児科
講師
研究者情報
研究キーワード
- 小児血液学, 小児腫瘍学, がん免疫療法, 造血幹細胞移植, キメラ抗原受容体(CAR)T細胞療法
メールアドレス
- kohira★shinshu-u.ac.jp
経歴
学歴
研究活動情報
論文
- Factors Affecting Day-to-Day Variations in Tacrolimus Concentration among Children and Young Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Yuta Maruyama, Yuya Maejima, Koichi Hirabayashi, Hirokazu Morokawa, Eri Okura, Shoji Saito, Yozo Nakazawa
Transplantation and Cellular Therapy, 29(4), 270e1-270e8, 2023年01月19日, 査読有り, 招待無し
責任著者
- Follow-up System for Childhood Cancer Survivors Via Germline Clinical Sequencing
Watanabe Tatsuo, Hirabayashi Koichi, Morita Daisuke, Yamaguchi Tomomi, Okura Eri, Morokawa Hirokazu, Saito Shoji, Tanaka Miyuki, Nakazawa Yozo, Kosho Tomoki
Shinshu Medical Journal, 70(3), 157-167, 2022年06月
- Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration
Hongxia Li, Emily B Harrison, Huizhong Li, Koichi Hirabayashi, Jing Chen, Qi-Xiang Li, Jared Gunn, Jared Weiss, Barbara Savoldo, Joel S Parker, Chad V Pecot, Gianpietro Dotti, Hongwei Du
NATURE COMMUNICATIONS, 13, 2154, 2022年04月20日 - Skin and soft tissue infections in adolescent chronic myeloid leukemia under dasatinib treatment
Eriko Uchida, Shoji Saito, Daisuke Morita, Eri Okura, Koichi Hirabayashi, Miyuki Tanaka, Hideyuki Nakazawa, Akane Minagawa, Yozo Nakazawa
Pediatric blood & cancer, 69(8), e29714, 2022年04月20日, 査読有り, 招待無し - Intraoperative Placement of an Absorbable Spacer Prior to Radiation Therapy for a Malignant Peripheral Nerve Sheath Tumor
Yuki Endo, Taichi Fukuzawa, Masahiro Irie, Hideyuki Sasaki, Hironori Kudo, Ryo Ando, Ryuji Okubo, Saori Katayama, Masatoshi Hashimoto, Kosuke Sato, Masahito Tachibana, Hidekazu Aoki, Masayuki Araya, Koichi Hirabayashi, Shoji Saito, Hidekazu Masaki, Yozo Nakazawa, Yoji Sasahara, Motoshi Wada
Case Reports in Oncology, 15(2), 541-546, 2022年03月20日, 査読有り, 招待無し - Comment on: Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients
Daisuke Matsuoka, Koichi Hirabayashi, Tsubasa Murase, Shoji Saito, Yozo Nakazawa
Pediatric blood & cancer, 69(9), e29634, 2022年03月02日, 査読有り, 招待無し
責任著者 - Dual Targeting CAR-T Cells with Optimal Costimulation and Metabolic Fitness enhance Antitumor Activity and Prevent Escape in Solid Tumors
Koichi Hirabayashi, Hongwei Du, Yang Xu, Peishun Shou, Xin Zhou, Giovanni Fucá, Elisa Landoni, Chuang Sun, Yuhui Chen, Barbara Savoldo, Gianpietro Dotti
Nature Cancer, 2(9), 904-918, 2021年09月, 査読有り, 招待無し
筆頭著者 - Impact of acute kidney injury on overall survival in children and young adults undergoing allogeneic hematopoietic stem cell transplantation
Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 68(9), 2021年09月
- Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients
Matsuoka, Daisuke; Hirabayashi, Koichi; Murase, Tsubasa; Saito, Shoji; Hidaka, Yoshihiko; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 67(12), 2020年12月 - Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation
Shigemura, Tomonari; Sakashita, Kazuo; Okura, Eri; Morita, Daisuke; Komori, Kazutoshi; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Nakazawa, Yozo;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 111(5), 702-710, 2020年05月 - THEMIS-SHP1 Recruitment by 4-1BB Tunes LCK-Mediated Priming of Chimeric Antigen Receptor-Redirected T Cells
Sun, Chuang; Shou, Peishun; Du, Hongwei; Hirabayashi, Koichi; Chen, Yuhui; Herring, Laura E.; Ahn, Sarah; Xu, Yang; Suzuki, Kyogo; Li, Guangming; Tsahouridis, Ourania; Su, Lishan; Savoldo, Barbara; Dotti, Gianpietro;
CANCER CELL, 37(2), 216-+, 2020年 - In Vivo Administration of Recombinant Human Granulocyte Colony-Stimulating Factor Increases the Immune Effectiveness of Dendritic Cell-Based Cancer Vaccination
Shimodaira, Shigetaka; Yanagisawa, Ryu; Koya, Terutsugu; Hirabayashi, Koichi; Higuchi, Yumiko; Sakamoto, Takuya; Togi, Misa; Kato, Tomohisa, Jr.; Kobayashi, Takashi; Koizumi, Tomonobu; Koido, Shigeo; Sugiyama, Haruo;
VACCINES, 7(3), 2019年09月 - Cancer Immunotherapy with T Cells Carrying Bispecific Receptors That Mimic Antibodies
Ahn, Sarah; Li, Jingjing; Sun, Chuang; Gao, Keliang; Hirabayashi, Koichi; Li, Hongxia; Savoldo, Barbara; Liu, Rihe; Dotti, Gianpietro;
CANCER IMMUNOLOGY RESEARCH, 7(5), 773-783, 2019年05月 - Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning
Komori, Kazutoshi; Hirabayashi, Koichi; Morita, Daisuke; Hara, Yosuke; Kurata, Takashi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
PEDIATRIC TRANSPLANTATION, 23(3), 2019年05月 - Computationally Guided Design of Single-Chain Variable Fragment Improves Specificity of Chimeric Antigen Receptors
Krokhotin, Andrey; Du, Hongwei; Hirabayashi, Koichi; Popov, Konstantin; Kurokawa, Tomohiro; Wan, Xinhui; Ferrone, Soldano; Dotti, Gianpietro; Dokholyan, Nikolay, V;
MOLECULAR THERAPY-ONCOLYTICS, 15, 30-37, 2019年 - Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
Komori, Kazutoshi; Saito, Shoji; Araya, Masayuki; Morita, Daisuke; Kurata, Takashi; Hirabayashi, Koichi; Tanaka, Miyuki; Koiwai, Keiichiro; Tauchi, Katsunori; Masaki, Hidekazu; Nakazawa, Yozo;
PRACTICAL RADIATION ONCOLOGY, 9(5), 333-337, 2019年 - Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
Du, Hongwei; Hirabayashi, Koichi; Ahn, Sarah; Kren, Nancy Porterfield; Montgomery, Stephanie Ann; Wang, Xinhui; Tiruthani, Karthik; Mirlekar, Bhalchandra; Michaud, Daniel; Greene, Kevin; Herrera, Silvia Gabriela; Xu, Yang; Sun, Chuang; Chen, Yuhui; Ma, Xingcong; Ferrone, Cristina Rosa; Pylayeva-Gupta, Yuliya; Yeh, Jen Jen; Liu, Rihe; Savoldo, Barbara; Ferrone, Soldano; Dotti, Gianpietro;
CANCER CELL, 35(2), 221-+, 2019年 - Panobinostat inhibits the proliferation of CD34(+)CD38(-)cells under stimulation of hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia
Kurata, Takashi; Matsuda, Kazuyuki; Hirabayashi, Koichi; Shigemura, Tomonari; Sakashita, Kazuo; Nakahata, Tatsutoshi; Koike, Kenichi;
PEDIATRIC BLOOD & CANCER, 65(11), 2018年11月 - Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation
Yanagisawa, Toshimitsu; Saito, Shoji; Katsuyama, Yoshihiko; Hirabayashi, Koichi; Shigemura, Tomonari; Tanaka, Miyuki; Sakashita, Kazuo; Nakazawa, Yozo;
PEDIATRIC TRANSPLANTATION, 22(6), 2018年09月 - Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors
Hirabayashi, Koichi; Yanagisawa, Ryu; Saito, Shoji; Higuchi, Yumiko; Koya, Terutsugu; Sano, Kenji; Koido, Shigeo; Okamoto, Masato; Sugiyama, Haruo; Nakazawa, Yozo; Shimodaira, Shigetaka;
ANTICANCER RESEARCH, 38(4), 2227-2234, 2018年04月 - Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia
Hirabayashi, Koichi; Takatsuki, Mitsuho; Motobayashi, Mitsuo; Kurata, Takashi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Ishizone, Satoshi; Ota, Hiroyoshi; Koike, Kenichi;
PEDIATRICS AND NEONATOLOGY, 58(1), 81-84, 2017年02月 - Anaplastic large-cell lymphoma of the left ventricle presenting with arrhythmia and cerebral infarction due to cardiogenic embolism (vol 63, pg 755, 2016)
Hirabayashi, Koichi; Yamauchi, Shoko; Matsuzaki, Satoshi; Komatsu, Kazunori; Sano, Kenji; Koike, Kenichi; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 63(6), 1132-1132, 2016年06月 - Clinical and Laboratory Outcomes After Umbilical Cord Blood Transplantation in a Patient with Mucolipidosis II Alpha/Beta
Shibazaki, Takumi; Hirabayashi, Koichi; Saito, Shoji; Shigemura, Tomonari; Nakazawa, Yozo; Sakashita, Kazuo; Takagi, Mineo; Shiohara, Masaaki; Adachi, Kaori; Nanba, Eiji; Sakai, Norio; Koike, Kenichi;
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 170(5), 1278-1282, 2016年05月 - Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction
Hirabayashi, Koichi; Kurata, Takashi; Horiuchi, Kazuki; Saito, Shoji; Shigemura, Tomonari; Tanaka, Miyuki; Yanagisawa, Ryu; Matsuda, Kazuyuki; Sakashita, Kazuo; Koike, Kenichi; Nakazawa, Yozo;
PEDIATRIC BLOOD & CANCER, 63(4), 709-711, 2016年04月 - Dendritic Cell-Based Adjuvant Vaccination Targeting Wilms' Tumor 1 in Patients with Advanced Colorectal Cancer.
Shimodaira S, Sano K, Hirabayashi K, Koya T, Higuchi Y, Mizuno Y, Yamaoka N, Yuzawa M, Kobayashi T, Ito K, Koizumi T.
Vaccines (Basel), 3(4), 1004-18, 2015年12月 - Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature
Saito, Shoji; Yanagisawa, Ryu; Yoshikawa, Kentaro; Higuchi, Yumiko; Koya, Terutsugu; Yoshizawa, Kiyoshi; Tanaka, Miyuki; Sakashita, Kazuo; Kobayashi, Takashi; Kurata, Takashi; Hirabayashi, Koichi; Nakazawa, Yozo; Shiohara, Masaaki; Yonemitsu, Yoshikazu; Okamoto, Masato; Sugiyama, Haruo; Koike, Kenichi; Shimodaira, Shigetaka;
CYTOTHERAPY, 17(3), 330-335, 2015年03月 - Dramatic Improvement in the Multifocal Positron Emission Tomography Findings of a Young Adult with Chronic Granulomatous Disease Following Allogeneic Hematopoietic Stem Cell Transplantation
Shigemura, Tomonari; Nakazawa, Yozo; Hirabayashi, Koichi; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Koike, Kenichi;
JOURNAL OF CLINICAL IMMUNOLOGY, 35(1), 84-86, 2015年01月 - Mudd's disease (MAT I/III deficiency): a survey of data for MAT1A homozygotes and compound heterozygotes
Chien, Yin-Hsiu; Abdenur, Jose E.; Baronio, Federico; Bannick, Allison Anne; Corrales, Fernando; Couce, Maria; Donner, Markus G.; Ficicioglu, Can; Freehauf, Cynthia; Frithiof, Deborah; Gotway, Garrett; Hirabayashi, Koichi; Hofstede, Floris; Hoganson, George; Hwu, Wuh-Liang; James, Philip; Kim, Sook; Korman, Stanley H.; Lachmann, Robin; Levy, Harvey; Lindner, Martin; Lykopoulou, Lilia; Mayatepek, Ertan; Muntau, Ania; Okano, Yoshiyuki; Raymond, Kimiyo; Rubio-Gozalbo, Estela; Scholl-Buergi, Sabine; Schulze, Andreas; Singh, Rani; Stabler, Sally; Stuy, Mary; Thomas, Janet; Wagner, Conrad; Wilson, William G.; Wortmann, Saskia; Yamamoto, Shigenori; Pao, Maryland; Blom, Henk J.;
ORPHANET JOURNAL OF RARE DISEASES, 10, 2015年 - Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia
Matsuda, K; Nakazawa, Y; Iwashita, C; Kurata, T; Hirabayashi, K; Saito, S; Tanaka, M; Yoshikawa, K; Yanagisawa, R; Sakashita, K; Sasaki, S; Honda, T; Koike, K
Leukemia, 28(7), 1545-1548, 2014年07月 - Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies
Hirabayashi, Kanae; Nakazawa, Yozo; Matsuura, Hiroki; Hara, Yosuke; Kurata, Takashi; Hirabayashi, Koichi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 99(4), 477-486, 2014年04月 - Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis
Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Kentaro; Hirabayashi, Koichi; Saito, Shoji; Kobayashi, Norimoto; Sakashita, Kazuo; Shiohara, Masaaki; Wada, Taizo; Shimodaira, Shigetaka; Agematsu, Kazunaga; Koike, Kenichi;
TRANSFUSION, 54(3), 516-521, 2014年03月 - Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies
Hirabayashi, Koichi; Nakazawa, Yozo; Sakashita, Kazuo; Kurata, Takashi; Saito, Shoji; Yoshikawa, Kentaro; Tanaka, Miyuki; Yanagisawa, Ryu; Koike, Kenichi;
SCIENTIFIC REPORTS, 4, 2014年 - Usefulness of Allogeneic Hematopoietic Stem Cell Transplantation in First Complete Remission for Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm With Skin Involvement: A Case Report and Review of Literature
Sakashita, Kazuo; Saito, Shoji; Yanagisawa, Ryu; Tanaka, Miyuki; Yoshikawa, Kentaro; Hirabayashi, Koichi; Tsukahara, Keiko; Motobayashi, Mitsuo; Nakazawa, Yozo; Koike, Kenichi;
PEDIATRIC BLOOD & CANCER, 60(11), E140-E142, 2013年11月 - Successful ganciclovir therapy in a patient with human herpesvirus-6 encephalitis after unrelated cord blood transplantation: usefulness of longitudinal measurements of viral load in cerebrospinal fluid.
Hirabayashi K, Nakazawa Y, Katsuyama Y, Yanagisawa T, Saito S, Yoshikawa K, Shigemura T, Sakashita K, Ichikawa M, Koike K
Infection, 41(1), 219-223, 2013年02月 - Neurologically normal development of a patient with severe methionine adenosyltransferase I/III deficiency after continuing dietary methionine restriction
Hirabayashi, Koichi; Shiohara, Masaaki; Yamada, Kazuhiro; Sueki, Akane; Ide, Yuichiro; Takeuchi, Koichi; Hagimoto, Rokuro; Kinoshita, Tatsuya; Yabuhara, Akihiko; Mudd, S. Harvey; Koike, Kenichi;
GENE, 530(1), 104-108, 2013年 - Food allergy after cord blood transplantation in children
Sakashita, Kazuo; Nakazawa, Yozo; Yanagisawa, Ryu; Tanaka, Miyuki; Saito, Shoji; Yoshikawa, Kentaro; Hirabayashi, Koichi; Kusakari, Mai; Kato, Sawako; Hidaka, Nao; Nakayama, Yoshiko; Shigemura, Tomonari; Kobayashi, Norimoto; Kobayashi, Mikiko; Shiohara, Masaaki; Koike, Kenichi;
BRITISH JOURNAL OF HAEMATOLOGY, 158(5), 672-676, 2012年09月 - Critical Illness Polyneuropathy and Myopathy Caused by Bacillus Cereus Sepsis in Acute Lymphoblastic Leukemia
Hirabayashi, Koichi; Shiohara, Masaaki; Suzuki, Takefumi; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 34(3), E110-E113, 2012年04月 - Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome
Hirabayashi, Koichi; Shiohara, Masaaki; Takahashi, Daijiro; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Sakashita, Kazuo; Nakamura, Tomohiko; Ishii, Eizaburo; Koike, Kenichi;
LEUKEMIA & LYMPHOMA, 52(8), 1523-1527, 2011年08月 - Polymyxin-Direct Hemoperfusion for Sepsis-Induced Multiple Organ Failure
Hirabayashi, Koichi; Shiohara, Masaaki; Saito, Shoji; Tanaka, Miyuki; Yanagisawa, Ryu; Tsuruta, Goro; Fukuyama, Tetsuhiro; Hidaka, Yoshihiko; Nakazawa, Yozo; Shimizu, Takashi; Sakashita, Kazuo; Koike, Kenichi;
PEDIATRIC BLOOD & CANCER, 55(1), 202-205, 2010年
