竹下 敏一 (タケシタ トシカズ)
学術研究院（医学系）
医学部 医学科 病理組織学
特任教授
研究者情報
研究活動情報
論文
- MK-6, a novel not-alpha IL-2, elicits a potent antitumor activity by improving the effector to regulatory T cell balance
Kobayashi, Maki; Kojima, Katsuhiko; Murayama, Kazutaka; Amano, Yuji; Koyama, Takashi; Ogama, Naoko; Takeshita, Toshikazu; Fukuhara, Tatsuro; Tanaka, Nobuyuki;
CANCER SCIENCE, 112(11), 4478-4489, 2021年11月
- Relationship between allergic sensitisation-associated single-nucleotide polymorphisms and allergic transfusion reactions and febrile non-haemolytic transfusion reactions in paediatric cases.
Yuichiro Ide, Ryu Yanagisawa, Jun Kobayashi, Kazutoshi Komori, Kazuyuki Matsuda, Yuji Amano, Yozo Nakazawa, Toshikazu Takeshita, Kazuo Sakashita, Minoru Tozuka
Blood Transfusion, 2021年02月03日, 査読有り - A low-frequency IL-4R locus variant in Japanese patients with intravenous immunoglobulin therapy-unresponsive Kawasaki disease.
Amano Y., Akazawa K., Yasuda J., Yoshino K., Kojima K., Kobayashi K., Matsuzaki S., Nakasaki M.,Kawai Y., Minegishi N., Ishida N., Motoki N.,Hachiya A.,Nakazawa Y.,Yamamoto M., Koike K. Takeshita T
Pediatr Rheumatol, (17(1):34), 2019年07月03日
- Physical interaction of junctophilin and the Ca(V)1.1 C terminus is crucial for skeletal muscle contraction
Nakada, Tsutomu; Kashihara, Toshihide; Komatsu, Masatoshi; Kojima, Katsuhiko; Takeshita, Toshikazu; Yamada, Mitsuhiko;
Proceedings of the National Academy of Sciences of the United States of America, 115(17), 4507-4512, 2018年 - Angiotensin II activates Ca(V)1.2 Ca2+ channels through beta-arrestin2 and casein kinase 2 in mouse immature cardiomyocytes
Kashihara, Toshihide; Nakada, Tsutomu; Kojima, Katsuhiko; Takeshita, Toshikazu; Yamada, Mitsuhiko;
JOURNAL OF PHYSIOLOGY-LONDON, 595(13), 4207-4225, 2017年 - Morphogenetic and molecular analyses of cyst wall components in the ciliated protozoan Colpoda cucullus Nag-1
Funadani R, Sogame Y, Kojima K, Takeshita T, Yamamoto K, Tsujizono T, Suizu F, Miyata S, Yagyu KI, Suzuki T, Arikawa M, Matsuoka T
FEMS Microbiol Lett, 363(18), fnw203, 2016年09月 - ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule(STAM) and the complex formation with STAM promotes its endosomal dissociation (vol 289, pg 33296, 2014)
Kojima, Katsuhiko; Amano, Yuji; Yoshino, Kazuhisa; Tanaka, Nobuyuki; Sugamura, Kazuo; Takeshita, Toshikazu;
JOURNAL OF BIOLOGICAL CHEMISTRY, 290(13), 8065-8066, 2015年 - ESCRT-0 Protein Hrs Is Targeted to Endosomes Independent of STAM and the Complex Formation with STAM Promotes Its Endosomal Dissociation.
1. Kojima K., Amano Y., Yoshino K., Tanaka N., Sugamura K., Takeshita T.
JOURNAL OF BIOLOGICAL CHEMISTRY, 289, 33296-33310, 2014年 - A hydrophobic amino acid cluster inserted into the C-terminus of a recycling cell surface receptor functions as an endosomal sorting signal.
Amano Y., Yoshino K, Kojima K., Takeshita T
Biochem Biophys Res Commun, 441, 164-168, 2013年 - Protein phosphorylation in encystment-induced Colpoda cucullus: localization and identification of phosphoproteins
Yoichiro Sogame, Katsuhiko Kojima, Toshikazu Takeshita, Sigeki Fujiwara, Seiji Miyata, Eiji Kinoshita, Tatsuomi Matsuoka
FEMS Microbiology Letters (in press), 2012年 - Hrs Recognizes a Hydrophobic Amino Acid Cluster in Cytokine Receptors during Ubiquitin-independent Endosomal Sorting
Yuji Amano, Yuki Yamashita, Katsuhiko Kojima, Kazuhisa Yoshino, Nobuyuki Tanaka, Kazuo Sugamura and Toshikazu Takeshita
JOURNAL OF BIOLOGICAL CHEMISTRY, 286(17), 15458-15472, 2011年 - Identification of a high incidence region for retroviral vector integration near exon 1 of the LMO2 locus
Yamada, Koichiro; Tsukahara, Tomonori; Yoshino, Kazuhisa; Kojima, Katsuhiko; Agawa, Hideyuki; Yamashita, Yuki; Amano, Yuji; Hatta, Mariko; Matsuzaki, Yasunori; Kurotori, Naoki; Wakui, Keiko; Fukushima, Yoshimitsu; Osada, Ryosuke; Shiozawa, Tanri; Sakashita, Kazuo; Koike, Kenichi; Kumaki, Satoru; Tanaka, Nobuyuki; Takeshita, Toshikazu
RETROVIROLOGY, 6, 79,, 2009年09月 - Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain
Yamashita, Yuki; Kojima, Katsuhiko; Tsukahara, Tomonori; Agawa, Hideyuki; Yamada, Koichiro; Amano, Yuji; Kurotori, Naoki; Tanaka, Nobuyuki; Sugamura, Kazuo; Takeshita, Toshikazu;
JOURNAL OF CELL SCIENCE, 121(10), 1727-1738, 2008年 - Murine leukemia virus vector integration favors promoter regions and regional hot spots in a human T-cell line.
Tsukahara T., Agawa H., Matsumoto S., Matsuda M., Ueno S., YamashitaY., Yamada K., Tanaka N., Kojima K., Takeshita T
Biochem Biophys Res Commun., 345, 1099-1107,, 2006年 - Deborah Brancho（他９名）Davis.: Mechanism of p38 MAP kinase activation in vivo.2.
Genes Dev., 17, 1969-1978,, 2003年 - IL2レセプターγ鎖
竹下敏一
Annual Review免疫, 113-118, 1994年 - Cloning of the gamma chain of human IL-2 receptor
Takeshita, T., Asao, H., Ohtani, K., Ishii, N., Tanaka, N., Munakata, H., Nakamura, M., Sugamura, K.
science, 257, 379-382, 1992年, 査読有り
筆頭著者 - IL-2レセプターの新たなサブユニット, γ鎖
竹下敏一
臨免疫, 23, 1066-1072, 1991年
