博士(工学), 北九州市立大学

Exploring the effects of glyco-copolymer architectures on the solution self-assembly of amphiphilic thermoresponsive linear, star, and cyclic polymers
Naoki Ozawa, Ji Ha Lee, Isamu Akiba, Tomoki Nishimura
Polymer Chemistry, in press, 2023年

Countercation Engineering of Graphene-Oxide Nanosheets for Imparting a Thermoresponsive Ability
Shoma Kondo, Tomoki Nishimura, Yuta Nishina, Koki Sano
ACS Applied Materials & Interfaces, in press, 2023年

Bilayer-domain formation of thermoresponsive amphiphilic block copolymers in hybrid liposomes for synthetic molecular channels
Naoki Ozawa, Shunji Kosaka, Shota Fujii, Tomoki Nishimura
Polymer Chemistry, 14, 2198, 2023年

Development of a Water-Dispersible Supramolecular Complex of Polyphenol with Polypeptides for Attenuation of the Allergic Response using a Mechanochemical Strategy
Riku Kawasaki, Shogo Kawamura, Tomoki Kodama, Keita Yamana, Akira Maeda, Dilimulati Yimiti, Shigeru Miyaki, Shodai Hino, Naoki Ozawa, Tomoki Nishimura, Seiji Kawamoto, Atsushi Ikeda
Macromolecular Bioscience, 23(4), 2200462, 2023年

Fluorescence sensor using porous host molecules deposited on filter paper with vapochromic and mechanochromic properties
Sota Umezane, Satoshi Fukutomi, Toshikazu Ono*, Yoshio Hisaeda, Tomoki Nishimura, Riku Kawasaki, Atsushi Ikeda
NEW JOURNAL OF CHEMISTRY, 47, 4166, 2023年

A solid-in-oil-in-water emulsion: An adjuvant-based immune-carrier enhances vaccine effect
Yoshiro Tahara, Riko Mizuno, Tomoki Nishimura, Sada-atsu Mukai, Rie Wakabayashi, Noriho Kamiya, Kazunari Akiyoshi, Masahiro Goto
BIOMATERIALS, 282, 121385, 2022年

Theranostic Agent Combining Fullerene Nanocrystals and Gold Nanoparticles for Photoacoustic Imaging and Photothermal Therapy
Riku Kawasaki, Kosuke Kondo, Risako Miura, Keita Yamana, Hinata Isozaki, Risako Shimada, Shogo Kawamura, Hidetoshi Hirano, Tomoki Nishimura, Naoki Tarutani, Kiyofumi Katagiri, Alexandra Stubelius, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi, Atsushi Ikeda
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(9), 4686, 2022年

Supramolecular Shear-Thinning Glycopeptide Hydrogels for Injectable Enzyme Prodrug Therapy Applications
Yusuke Sakamoto, Fumi Suehiro, Isamu Akiba, Tomoki Nishimura
LANGMUIR, 38(18), 5883, 2022年

Single-component nanodiscs via the thermal folding of amphiphilic graft copolymers with the adjusted flexibility of the main chain
Tomoki Nishimura, Yusuke Hatatani, Mitsuru Ando, Yoshihiro Sasaki, Kazunari Akiyoshi
Chemical Science, 13(5243), 2022年

Bioorthogonal micellar nanoreactors for prodrug cancer therapy using an inverse-electron-demand Diels–Alder reaction
Fumi Suehiro, Shota Fujii, Tomoki Nishimura
Chemical Communications, 58, 7026, 2022年

Circularly Polarized Luminescence Active Supramolecular Nanotubes Based on Pt(II) Complexes that Undergo Dynamic Morphological Transformation and Helicity Inversion
Seok Gyu Kang, Ka Young Kim, Yumi Cho, Dong Yeun Jeong, Ji Ha Lee, Tomoki Nishimura, Shim Sung Lee, Sang Kyu Kwak, Youngmin You, Jong Hwa Jung
Angewandte Chemie International Edition, 66(38), e202207310, 2022年

Glycopeptoid Nanospheres: Glycosylation-Induced Coacervation of Poly(sarcosine)
Yota Okuno, Tomoki Nishimura, Yoshihiro Sasaki, Kazunari Akiyoshi
NANOSCALE ADVANCES, 4, 3707, 2022年

Recent advances in the self-assembly of sparsely grafted amphiphilic copolymers in aqueous solution
Yusuke Sakamoto, Tomoki Nishimura
Polymer Chemistry, 13, 6343, 2022年

Thermoresponsive Glycopolymer Vesicles: In situ Observation of Morphological Changes and Triggered Cargo Release
Tomoki Nishimura, Yoshihiro Sasaki, Kazunari Akiyoshi
POLYMER JOURNAL, 53, 1251, 2021年

Magnetically Navigated Protein Transduction In Vivo using Iron Oxide-Nanogel Chaperone Hybrid
Riku Kawasaki, Yoshihiro Sasaki, Tomoki Nishimura, Kiyofumi Katagiri, Kei‐ichi Morita, Yurina Sekine, Shin-ichi Sawada, Sada-atsu Mukai, Kazunari Akiyoshi
Advanced Healthcare Materials, 10(9), 2001988, 2021年

Thermoresponsive Carbohydrate-b-Polypeptoid Polymer Vesicles with Selective Solute Permeability and Permeable Factors for Solutes
Yota Okuno, Tomoki Nishimura, Yoshihiro Sasaki, Kazunari Akiyoshi
Biomacromolecules, 22(7), 3099, 2021年

Manipulating the Morphology of Amphiphilic Graft-Copolymer Assemblies by Adjusting the Flexibility of the Main Chain
Tomoki Nishimura, Shota Fujii, Kazuo Sakurai, Yoshihiro Sasaki, Kazunari Akiyoshi
Macromolecules, 54(14), 7003, 2021年

Preparation of Aqueous Solutions with Information on Solids (ASIS) of a Mechanochromic Luminescent Tetraphenylethylene Derivative by Complexation with Polysaccharides
Riku Omokawa, Riku Kawasaki, Kouta Sugikawa, Tomoki Nishimura, Toshimi Nakaya, Atsushi Ikeda
ACS Applied Polymer Materials, 3(8), 3708, 2021年

Substrate-sorting nanoreactors based on permeable peptide polymer vesicles and hybrid liposomes with synthetic macromolecular channels
Tomoki Nishimura, Shin Hirose, Yoshihiro Sasaki, Kazunari Akiyoshi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(1), 154, 2020年

Artificial Molecular Chaperone Systems for Proteins, Nucleic Acids, and Synthetic Molecules
Tomoki Nishimura, Kazunari Akiyoshi
Bioconjugate chemistry, 31(5), 1259, 2020年

Thermoresponsive Polysaccharide Graft Polymer Vesicles with Tunable Size and Structural Memory
Tomoki Nishimura, Shen Shishi, Yoshihiro Sasaki, Kazunari Akiyoshi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(27), 11784, 2020年

Determining the Hydration in the Hydrophobic Layer of Permeable Polymer Vesicles by Neutron Scattering
Tomoki Nishimura, Liliana de Campo, Hiroki Iwase, Kazunari Akiyoshi
Macromolecules, 53(17), 7546, 2020年

Biocatalytic Hybrid Films Self-Assembled from Carbohydrate Block Copolymers and Polysaccharides for Enzyme Prodrug Therapy
Tomoki Nishimura, Yusuke Nakamura, Naoya Kinoshita, Katsuhiro Yamamoto, Yoshihiro Sasaki, Kazunari Akiyoshi
ACS Applied Bio Materials, 3(12), 8865, 2020年

Intrinsically permeable polymer vesicles based on carbohydrate-conjugated poly(2-oxazoline) s synthesized using a carbohydrate-based initiator system
Tomoki Nishimura, Naoki Sumi, Yuta Koda, Yoshihiro Sasaki, Kazunari Akiyoshi
Polymer Chemistry, 10(6), 691, 2019年

Synthesis and function of amphiphilic glucan dendrimers as nanocarriers for protein delivery
Shigeo Takeda, Tomoki Nishimura, Kaori Umezaki, Akiko Kubo, Michiyo Yanase, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
Biomaterials, Science, 7(4), 1617, 2019年

Supramacromolecular injectable hydrogels by crystallization-driven self-assembly of carbohydrate-conjugated poly(2-isopropyloxazoline) s for biomedical applications
Tomoki Nishimura, Naoki Sumi, Sada-atsu Mukai, Yoshihiro Sasaki, Kazunari Akiyoshi
JOURNAL OF MATERIALS CHEMISTRY B, 7(14), 6362, 2019年

Biotransporting biocatalytic reactors toward therapeutic nanofactories
Tomoki Nishimura, Kazunari Akiyoshi
ADVANCED SCIENCE, 5(11), 1800801, 2018年

Synthesis and Characterization of Shell‐Cross‐Linked Glycopolymer Bilayer Vesicles
Tomoki Nishimura, Wei‐Lun Toh, Kazunari Akiyoshi
MACROMOLECULAR RAPID COMMUNICATIONS, 39(23), 1800384, 2018年

Amylose engineering: phosphorylase‐catalyzed polymerization of functional saccharide primers for glycobiomaterials
Tomoki Nishimura, Kazunari Akiyoshi
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(2), e1423, 2017年

Biotransporting Self‐Assembled Nanofactories Using Polymer Vesicles with Molecular Permeability for Enzyme Prodrug Cancer Therapy
Tomoki Nishimura, Yoshihiro Sasaki, Kazunari Akiyoshi
ADVANCED MATERIALS, 29(36), 1702406, 2017年

Self-assembled polypeptide nanogels with enzymatically transformable surface as a small interfering RNA delivery platform
Tomoki Nishimura, Akina Yamada, Kaori Umezaki, Shin-ichi Sawada, Sada-atsu Mukai, Yoshihiro Sasaki, Kazunari Akiyoshi
Biomacromolecules, 18(15), 3913, 2017年

A light sensitive self-assembled nanogel as a tecton for protein patterning materials
Tomoki Nishimura, Masahiro Takara, Sada-atsu Mukai, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
Chemical Communications, 52(6), 1222, 2016年

Self-assembled nanogels of cholesterol-bearing hydroxypropyl cellulose: a thermoresponsive building block for nanogel tectonic materials
Yoshiro Tahara, Mizuki Sakiyama, Shigeo Takeda, Tomoki Nishimura, Sada-atsu Mukai, Shin-ichi Sawada, Yoshihiro Sasaki, Kazunari Akiyoshi
LANGMUIR, 32(47), 12283, 2016年

Glyco star polymers as helical multivalent host and biofunctional nano-platform
Tomoki Nishimura, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi
ACS Macro Letters, 4(4), 367, 2015年

Long-lasting and efficient tumor imaging using a high relaxivity polysaccharide nanogel magnetic resonance imaging contrast agent
Minnie Chan, Jacques Lux, Tomoki Nishimura, Kazunari Akiyoshi, Adah Almutairi
Biomacromolecules, 16(9), 2964, 2015年

Amylose-based cationic star polymers for siRNA delivery
Tomoki Nishimura, Kaori Umezaki, Sada-atsu Mukai, Shin-ichi Sawada, Kazunari Akiyoshi
BioMed Research International, 962941, 2015年

A bimolecular micelle constructed from amphiphilic pillar [5] arene molecules
Tomoki Nishimura, Yusuke Sanada, Takuma Matsuo, Tadashi Okobira, Efstratios Mylonas, Naoto Yagi, Kazuo Sakurai
Chemical Commucations, 46(23), 3052, 2013年

A simple visual sensor with the potential for determining the concentration of fluoride in water at environmentally significant levels
Tomoki Nishimura, Su-Ying Xu, Yun-Bao Jiang, John S Fossey, Kazuo Sakurai, Steven D Bull, Tony D James
Chemical Communications, 46(23), 3052, 2013年

Pyrene-anchored boronic acid receptors on carbon nanoparticle supports: fluxionality and pore effects
Katherine Lawrence, Tomoki Nishimura, Peter Haffenden, John M Mitchels, Kazuo Sakurai, John S Fossey, Steven D Bull, Tony D James Frank Marken
NEW JOURNAL OF CHEMISTRY, 37(7), 1883, 2013年

A stimulus-responsive shape-persistent micelle bearing a calix [4] arene building block: reversible pH-dependent transition between spherical and cylindrical forms
Shota Fujii, Yusuke Sanada, Tomoki Nishimura, Isamu Akiba, Kazuo Sakurai, Naoto Yagi Efstratios Mylonas
LANGMUIR, 28(6), 3092, 2012年

Thermodynamics of lipoplex formation: relationship between the lipid alkyl tail length and thermodynamic functions
Shota Fujii, Tomoki Nishimura, Kazuo Sakurai
Chemistry Letters, 41(5), 501, 2012年

Metal-ion induced transition from multi-to single-bilayer tubes in histidine bearing lipids and formation of monodisperse Au nanoparticles
Tomoki Nishimura, Takuma Matsuo, Kazuo Sakurai
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 13(35), 15899, 2011年

Quaternary-ammonium-bearing Aromatic Surfactants: Effect of the Alkyl Chain Positions on Their Micelle and DNA-complex Structures
Takuma Matsuo, Shota Fujii, Yumi Kamikawa, Tomoki Nishimura, Yusuke Sanada, Shinichi Mochizuki, Kazuo Sakurai
Chemistry Letters, 40(12), 1340, 2011年

Cation-specific Transition from Vesicle to Lamella for an Aromatic Diamine Lipid in Aqueous Solutions
Tomoki Nishimura, Hiroyasu Masunaga, Hiroki Ogawa, Isamu Akiba, Kazuo Sakurai
Chemistry Letters, 39(7), 686, 2010年

Synthesis of a highly hydrophobic cationic lipid and structural and thermodynamic studies for interaction with DNA
Tomoki Nishimura, Takeshi Cho, Andrew M Kelley, Magdalena E Powell, John S Fossey, Steven D Bull, Tony D James, Hiroyasu Masunaga, Isamu Akiba, Kazuo Sakurai
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 83(9), 1010, 2010年

DNA conformational switching by use of an intercalator and its receptor
Tomoki Nishimura, Yoichi Takeda, Naohiko Shimada, Kazuo Sakurai
Chemistry Letters, 36(3), 388, 2007年

DNA binding of tilorone: 1H NMR and calorimetric studies of the intercalation
Tomoki Nishimura, Tadashi Okobira, Andrew M Kelly, Naohiko Shimada, Yoichi Takeda, Kazuo Sakurai
Biochemistry, 46(27), 8156, 2007年