TAKAYA Tomohide
Institute of Agriculture, School of Science and Technology, Academic Assembly
Faculty of Agriculture Department of Agricultural and Life Sciences Division of Animal Science
Associate Professor
Researcher Information
Research Keyword
- Stem cell, regeneration, Skeletal muscle
Address
- 8304 Minami-minowa, Kami-ina, Nagano 399-4598, Japan
Mail Address
- ttakaya★shinshu-u.ac.jp
Web site
Career
- 2023
Associate Professor, Faculty of Agriculture, Shinshu University - 2015 - 2023
Assistant Professor, Faculty of Agriculture, Shinshu University - 2014 - 2015
Post-doctroral Fellow for Research Abroad, Japan Society for the Promotion of Science - 2013 - 2015
Post-doctoral Associate, Stem Cell Institute, University of Minnesota Medical School - 2011 - 2012
Research Fellow, Department of Vascular Physiology, National Cerebral and Cardiovascular Center Research Institute - 2009 - 2011
Research Fellow for Doctoral Course Students (DC2), Japan Society for the Promotion of Science - 2005 - 2009
Research Fellow, Division of Translational Research, National Hospital Organization Kyoto Medical Center
Research activity information
Award
Paper
- Lectin-like oxidized low-density lipoprotein receptor-1 plays an important role in vascular inflammation in current smokers.
Takanabe-Mori R, Ono K, Wada H, Takaya T, Ura S, Yamakage H, Satoh-Asahara N, Shimatsu A, Takahashi Y, Fujita M, Fujita Y, Sawamura T, Hasegawa K.
J Atheroscler Thromb, 20(6), 585-590, 2013, Refereed - Highly purified eicosapentaenoic acid increases interleukin-10 levels of peripheral blood monocytes in obese patients with dyslipidemia.
Satoh-Asahara N, Shimatsu A, Sasaki Y, Nakaoka H, Himeno A, Tochiya M, Kono S, Takaya T, Ono K, Wada H, Suganami T, Hasegawa K, Ogawa Y.
Diabetes Care, 35(12), 2631-2639, 2012, Refereed - Distinct characteristics of circulating vascular endothelial growth factor-A and C levels in human subjects.
Wada H, Ura S, Kitaoka S, Satoh-Asahara N, Horie T, Ono K, Takaya T, Takanabe-Mori R, Akao M, Abe M, Morimoto T, Murayama T, Yokode M, Fujita M, Shimatsu A, Hasegawa K.
PLOS ONE, 6(12), e29351, 2011, Refereed - A natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin-converting enzyme inhibitor, exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats.
Sunagawa Y, Morimoto T, Wada H, Takaya T, Katanasaka Y, Kawamura T, Yanagi S, Marui A, Sakata R, Shimatsu A, Kimura T, Kakeya H, Fujita M, Hasegawa K.
Circ J, 75(9), 2151-2159, 2011, Refereed - MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes.
Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, Watanabe S, Takaya T, Tamaki Y, Takanabe-Mori R, Wada H, Hasegawa K, Iwanaga Y, Kawamura T, Kita T, Kimura T.
Mol Cell Biol, 31(4), 744-755, 2011, Refereed - Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice.
Takanabe-Mori R, Ono K, Sowa N, Wada H, Takaya T, Horie T, Satoh-Asahara N, Shimatsu A, Fujita M, Sawamura T, Hasegawa K.
Biochem Biophys Res Commun, 398(3), 576-580, 2010, Refereed
Lectures, oral presentations, etc.
- The temporal changes of physiologic functions and gene expressions in drug-induced skeletal muscle specific DUX4 over expression mice.
Yosizawa T, Miyazaki D, Takaya T, Nakada T, Nakamura A, Kosho T.
Joint Conference of the 22nd Annual Meeting of Asian Oceanian Myology Center and The 10th Annual Meeting of Japan Muscle Society, 13 Sep. 2024Analysis for time cause of skeletal muscle disorder in FSHD model mice
Yoshizawa T, Miyazaki D, Takaya T, Nakamura A, Kosho T.
The 71st Annual Meeting of the Japanese Association for Laboratory Animal Science, 31 May 2024Identification of a candidate drug for the treatment of facioscapulohumeral muscular dystrophy.
Yoshizawa T, Tomiyama Y, Shiba N, Takaya T, Miyazaki D, Nakada T, Shiba Y, Nakamura A, Kosho T.
Human Genetics Asia 2023, 13 Oct. 2023Possible chicken meat production by ex-ovo embryo culture system and the application for poultry biotechnology.
Shindo H, Saito S, Takizawa S, Murai K, Takaya T, Hiramatsu K, Kawahara T, Kagami H.
The 68th International Congress of Meat Science and Technology, 24 Aug. 2022Application of a novel chick embryo culture system for developmental studies and chicken meat production.
Murai K, Takizawa S, Saito S, Shindo H, Takaya T, Hiramatsu K, Kawahara T, Kagami H.
The 68th International Congress of Meat Science and Technology, 24 Aug. 2022Avian stem cell technologies for cellular agriculture.
Kagami H, Murai K, Takizawa S, Shindo H, Saito S, Takaya T, Hiramatsu K, Sheng G.
The 7th International Scientific Conference on Cultured Meat, 30 Nov. 2021Discovery and application of myogenetic oligodeoxynucleotides (myoDNs).
Takaya T.
International Joint Seminar 2019 Sejong University-Shinshu University-Kasetsart University, 24 Sep. 2019Action mechanism of myogenetic oligodeoxynucleotides (myoDNs).
Shinji S, Takaya T.
International Joint Seminar 2019 Sejong University-Shinshu University-Kasetsart University, 24 Sep. 2019Expression of helix-loop-helix transcription factor Ascl4 induces myogenic program in embryonic stem cells.
Asakura A, Kodaka Y, Watanabe S, Ito H, Verma M, Takaya T, Asakura Y, Kyba M.
Frontiers in Myogenesis Meeting, 24 Sep. 2019Application of myogenetic oligodeoxynucleotide to diabetic skeletal muscle myoblasts.
Nakamura S, Umezawa K, Yonekura S, Shimosato T, Takaya T.
日本核酸医薬学会第5回年会, 11 Jul. 2019RNA sequencing for global gene expression associated with proliferation and differentiation in chicken skeletal muscle myoblasts.
Nihashi Y, Umezawa K, Hamaguchi Y, Kobayashi H, Kono T, Ono T, Kagami H, Takaya T.
The 2nd International Conference on Tropical Animal Science and Production, 10 Jul. 2019Induction of cardiac differentiation of pluripotent stem cells by myogenetic oligodeoxynucleotide.
Ishioka M, Nihashi Y, Umezawa K, Kagami H, Shimosato T, Takaya T.
日本核酸医薬学会第5回年会, 10 Jul. 2019Conformational difference between two types of biologically active oligodeoxynucleotides.
Umezawa K, Yamamoto Y, Shimosato T, Takaya T.
日本核酸医薬学会第5回年会, 10 Jul. 2019Myogenic differentiation-inducing oligodeoxynucleotide recovers the myoblast differentiation impaired by abnormal glucose concentration.
Nakamura S, Yonekura S, Shimosato T, Takaya T.
The 4th International Conference on Pharma-Food, 15 Nov. 2018Toll-like receptor ligand-dependent inflammatory responses in chick skeletal muscle myoblasts.
Nihashi Y, Ono T, Kagami H, Takaya T.
2018 International Symposium on Animal Science and Technology, 10 Aug. 2018Functional structure analyses of the DNA-alkaloid complex promoting myogenic differentiation.
Shinji S, Umezawa K, Shimosato T, Takaya T.
2018 International Symposium on Animal Science and Technology, 10 Aug. 2018Myogenic oligodeoxynucleotide, myoDN, induces myocardial differentiation of murine iPS cells.
Ishioka M, Nihashi Y, Kagami H, Shimosato T, Takaya T.
2018 International Symposium on Animal Science and Technology, 10 Aug. 2018Intermittent glucose stimulation impairs proliferation and differentiation of C2C12 myoblasts.
Nakamura S, Yonekura S, Takaya T.
2018 International Symposium on Animal Science and Technology, 10 Aug. 2018Developmental analysis of the donor mice ES cells in the recipient chick embryo.
Asai M, Kusudo T, Kobayashi K, Watanabe K, Ono T, Takaya T, Tomioka I, Kagami H.
2018 International Symposium on Animal Science and Technology, 10 Aug. 2018Comprehensive gene expression analyses between broiler and layer chick skeletal muscle myoblasts.
Takaya T.
2018 International Symposium on Animal Science and Technology, 09 Aug. 2018, InvitedDistinct expression of TLR genes between broiler and layer chick skeletal muscle myoblasts.
Nihashi Y, Ono T, Kagami H, Takaya T.
The 11th Asian Pacific Poulty Conference, 26 Mar. 2018Novel DNA aptamer activating skeletal muscle stem cells.
Takaya T.
Symposium on Advanced Materials and 3D Printing for Biomedical Applications, 20 Oct. 2017, InvitedRegulation of skeletal muscle stem cells for meat production.
Takaya T.
Japan-Thailand International Symposium on Animal Biotechnology, 05 Jul. 2017, InvitedAutonomous xenogenic cell fusion of murine and chick skeletal muscle myoblasts.
Takaya T, Nihashi Y, Kojima S, Ono T, Kagami H.
Japan-Thailand International Symposium on Animal Biotechnology, 05 Jul. 2017Distinct cell characteristics between broiler and layer chick skeletal muscle myoblasts.
Nihashi Y, Ono T, Kagami H, Takaya T.
Japan-Thailand International Symposium on Animal Biotechnology, 05 Jul. 2017Application of the oligodeoxynucleotide from lactic acid bacteria that promotes myogenic differentiation.
Shinji S, Nihashi Y, Umezawa K, Shimosato T, Takaya T.
Japan-Thailand International Symposium on Animal Biotechnology, 05 Jul. 2017Efficient production of chicks by ex ovo culture system with novel avian assisted reproductive technology (AART).
Sato S, Sato T, Miki S, Ono T, Takaya T, Kagami H.
Japan-Thailand International Symposium on Animal Biotechnology, 05 Jul. 2017Courses
- Animal Life Science (2016-)
Shinshu University - Seminar for Freshmen (2017-2021, 2023-)
Shinshu University - Reading of Foreign Articles I (2016)
Shinshu University - Biochemistry (2017-2022)
Shinshu University - Compendium of Animal Life Science (2017-)
Shinshu University - Bioanalytical Chemistry
Shinshu University - Special Lecture for Cutting Edge (2024-)
Shinshu University - Career Design (2018, 2023)
Shinshu University - Volunteer I (2018, 2023)
Shinshu University - Volunteer II (2018, 2023)
Shinshu University - Volunteer III (2018, 2023)
Shinshu University - Volunteer IV (2018, 2023)
Shinshu University - Internship I (2018, 2023)
Shinshu University - Internship II (2018, 2023)
Shinshu University - Internship III (2018, 2023)
Shinshu University - Animal Genetics and Breeding (2019)
Shinshu University - Studies on Domestic Animals (2021)
Shinshu University - Animal Science (2018)
Shinshu University - Animal Cell Biology (2022-)
Shinshu University - Biostatistics for Animal Experiments (2016-)
Shinshu University - Experiments in Animal Bioscience
Shinshu University - Hands-on Seminar on Farm Practices (2017, 2021, 2023)
Shinshu University - Scientific English II (2017-)
Shinshu University - Presentation I (2017-)
Shinshu University - Presentation II (2018-)
Shinshu University - Selected Seminar (2017-)
Shinshu University - Thesis Research I (2017-)
Shinshu University - Thesis Research II (2018-)
Shinshu University - Thesis Research (2018-)
Shinshu University - Advanced Lecture in Food, Agricultural and Environmental Sciences (2020, 2023)
Shinshu University - Advanced Lecture in Integrated Bioscience (2016-)
Shinshu University - Advanced Seminar for Integrated Bioscience (2016, 2023)
Shinshu University - Advanced Internship (2016, 2023)
Shinshu University - Special Research (2019-)
Shinshu University - Advanced Lecture in Animal Biotechnology (2018-)
Shinshu University - Advanced Seminar for Cellular Systems I (2018-)
Shinshu University - Advanced Seminar for Cellular Systems II (2018-)
Shinshu University - Advanced Experimental Course on Cellular Systems (2018-)
Shinshu University - Molecular Biotechnology (2018-)
Shinshu University - Special Seminar (2020-)
Shinshu University - Special Seminar on Research Subject
Shinshu University
Affiliated academic society
- Jan. 2018
Japanese Society of Anti-Aging Medicine - Jul. 2017
Nucleic Acids Therapeutics Society of Japan - Mar. 2017
Japan Poultry Science Association - Mar. 2017
Japan Society for Bioscience, Biotechnology, and Agrochemistry - Nov. 2016
Japanese Society of Animal Science - Apr. 2013
Japan Cardiovascular Association
Media Coverage
- iSN04: A novel nucleic acid drug for the treatment of vascular diseases
EurekAlert!, 20 Aug. 2024, Internet - DNA aptamer finds novel application in regulating cell differentiation
EurekAlert!, 10 Oct. 2023, Internet - Identification of osteogenetic oligodeoxynucleotide that promotes bone differentiation
EurekAlert!, 23 May 2022, Internet - Skeletal muscle loss exacerbated by diabetes improved with oligo DNA
EurekAlert!, 26 May 2021, Internet - Identification of oligo-DNA that promotes skeletal muscle differentiation
EurekAlert!, 25 Jan. 2021, Internet
Educational activity information