KANNO Hiroyuki
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
School of Medicine Department of Pathology
Professor
Researcher Information
Research Keyword
- Connective tissue disease, Epstein-Barr virus, immune disease, malignant lymphoma, Vasculitis
TEL
- +81-263-37-2608
Mail Address
- hirokan★shinshu-u.ac.jp
Career
- 2011
Professor, Shinshu University School of Medicine - 2002 - 2011
Associate Professor, Iwate Medical University - 2001 - 2001
文部省短期在外研究員（海外研究開発動向調査派遣） - 2000 - 2002
Associate Professor, Hokkaido University Institute for Genetic Medicine - 1993 - 1999
Assistent Professor and Associate Professor, Osaka University Medical School
Research activity information
Paper
- Establishment of Epstein-Barr virus (EBV) latent gene-expressing T-cell lines with an expression vector harboring EBV nuclear antigen 1
Kanno H, Osada T, Tateishi A
Microorganisms, 11, 2624, Oct. 2023, Refereed, Not invited
Lead, Corresponding - Expert perspectives on pathological findings in vasculitis.
1. Ishizu A, Kawakami T, Kanno H, Takahashi K, Miyazaki T, Ikeda E, Oharaseki T, Ogawa Y, Onimaru M, Kurata M, Nakazawa D, Muso E, Harigai M, for the Japan Research Committee of the Ministry of Health, Labour and Welfare for Intractable Vasculitis
Mod. Rheumatol., 33(1), 1-11, Jan. 2023, Refereed - An autopsy case of fulminant myocarditis after severe acute respiratory syndrome coronavirus 2 vaccine inoculation.
4. Satomi H, Katano H, Kanno H, Kobayashi M, Ohkuma Y, Hashidume N, Usui T, Tsukada S, Ito I
Pathol. Int., 72(10), 519-524, Oct. 2022, Refereed
Corresponding - 大型血管の血管炎
菅野祐幸、小林実喜子
病理と臨床, 39(11), 1106-1109, Nov. 2021, Invited
Lead, Corresponding - Spread of vimentin-immunoreactive cells within the plaque-like lesion in the spinal anterior horn of a patient with post-poliomyelitis syndrome.
Hineno A, Oyanagi K, Yoshida T, Sakai Y, Kanno H, Sekijima Y
Neuropathology, 41, 406-411, Oct. 2021, Refereed, Not invited - 皮膚悪性腫瘍（第２版下）—基礎と臨床の最新研究動向— VII皮膚リンパ腫 ３．臨床検査 （１）免疫組織化学(immunohistochemistry: IHC)検査
大谷真紀、菅野祐幸
日本臨床, 79(増刊号3), 413-417, Jul. 2021, Invited
Last - Orbital Epstein-Barr virus-related post-transplant lymphoproliferative disorder in a 13-year-old girl with cord blood transplantation.
5. Shigemura T, Maruyama Y, Shigeto S, Nakazawa Y, Kanno H
Transpl. Infect. Dis., 23(3), e13536, Jun. 2021, Refereed, Not invited
Last - 皮膚悪性腫瘍（第２版上）—基礎と臨床の最新研究動向— Iメラノーマ ２．メラノーマの分類と病理組織学 （４）免疫組織化学（免疫染色）
小林実喜子、布麻里奈、菅野祐幸
日本臨床, 79(増刊号2), 41-46, May 2021, Invited
Last - Histological and immunohistochemical evaluation of infiltrating inflammatory cells in Kawasaki disease arteritis lesions.
Kobayashi M, Matsumoto Y, Ohya M, Harada K, Kanno H
Appl. Immunohistochem. Mol. Morphol., 29(1), 62-67, Jan. 2021 - An anaplastic pleomorphic xanthoastrocytoma with periventricular extension: an autopsy scase report amd review of the literature.
Matsumoto Y, Kobayashi M, Shingu K, Tateishi A, Ohya M, Sano K, Negishi T, Shigeto S, Kobayashi T, Hara Y, Kakizawa Y, Kanno H
Neuropathology, 40, 507-514, Oct. 2020 - The ratio of CD163-positive macrophages to Iba 1-positive macrophages is low in the intima in the early stage of cutaneous arteritis.
Kobayashi M, Matsumoto Y, Satomi H, Tateishi A, Ohya M, Ito I, Kanno H
Immunologic Res., 68(3), 152-160, Jun. 2020 - Ultrastructure of CIC-DUX4 sarcoma: the first pathological report.
Tamada H, Kobayashi M, Sano K, Uehara T, Matsumoto Y, Tateishi A, Ohya M, Kito M, Aoki K, Kanno H
Ultrastruct. Pathol., 44(2), 237-277, Mar. 2020 - Automated acquisition of explainable knowledge from unannotated histopathology images.
Yamamoto Y, Tsuzuki T, Akatsuka J, Ueki M, Morikawa H, Numata Y, Takahara T, Tsuyuki T, Tsutsumi K, Nakazawa R, Shimizu A, Maeda I, Tsuchiya S, Kanno H, Kondo Y, Fukumoto M, Tamiya G, Ueda N, Kimura G
NATURE COMMUNICATIONS, 10(1), 5642, Dec. 2019 - Malignant peritoneal mesothelioma diagnosed 50 years post-radiotherapy for ovarian cancer in a patient with a history of multiple malignancies: An autopsy case.
Ohya M, Kobayashi M, Suzuki T, Kanno H, Nakazawa K.
Molecular and Clinical Oncology, 11(4), 397-400, Oct. 2019 - An autopsy case of widespread brain dissemination of glioblastoma unnoticed by magnetic resonance imaging after treatment with bevacizymab.
Hardian RF, Goto T, Kuwabara H, Hanaoka Y, Kobayashi S, Kanno H, Shimojo H, Horiuchi T, Hongo K.
Surgical Neurology International, 10, 137, Jul. 2019 - A fulminant case of classical Hodgkin lymphoma: A diagnostic dilemma of Epstein-Barr virus-positive large B-cell neoplasms.
Ichimata S, Kobayashi M, Ohya M, Otsuki T, Yanagisawa K, Tateishi K, Kato A, Matsuo A, Kanno H
Pathology Internaional, 69(7), 407-413, Jul. 2019 - Effects of Morinda citrifolia on Rheumatoid Arthritis in SKG Mice
Kustiarini, Dyah Aninta; Nishigaki, Toshiaki; Kanno, Hiroyuki; To, Hideto;
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 42(3), 496-500, Mar. 2019
- Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture
Hirashima, Kanji; Yue, Fengming; Kobayashi, Mikiko; Uchida, Yuriko; Nakamura, Shunsuke; Tomotsune, Daihachiro; Matsumoto, Ken; Takizawa-Shirasawa, Sakiko; Yokoyama, Tadayuki; Kanno, Hiroyuki; Sasaki, Katsunori;
CELL AND TISSUE RESEARCH, 375(3), 697-707, Mar. 2019
- Lower number of 5-hydroxymethylcytosine-expressing cells in plasma cell myeloma than in reactive plasma cell hyperplasia: a useful immunohistochemical approach for identification of neoplastic plasma cells
Ohya, Maki; Nakazawa, Koh; Kanno, Hiroyuki;
PATHOLOGY, 51(1), 81-85, Jan. 2019 - First pathological report of a de novo CD5-positive diffuse large B-cell lymphoma patient presenting with Guillain-Barre syndrome-like neuropathy due to neurolymphomatosis
Kobayashi, Mikiko; Sakai, Yasuhiro; Kariya, Yuta; Sakai, Hitoshi; Hineno, Akiyo; Oyanagi, Kiyomitsu; Kanno, Hiroyuki;
Neuropathology, 38(4), 417-421, Aug. 2018 - Usefulness of gastroduodenal biopsy in the differential diagnosis of systemic AH amyloidosis from systemic AL amyloidosis
Ichimata, Shojiro; Kobayashi, Mikiko; Shimojo, Hisashi; Katoh, Nagaaki; Yazaki, Masahide; Kanno, Hiroyuki;
HISTOPATHOLOGY, 73(2), 230-239, Aug. 2018 - Induction of Interleukin-10 in the Stable Transformants of Human T-Cell Line Expressing Epstein-Barr Virus-Encoded Small RNAs
Junaidi Ayako Tateishi, Hiroyuki Kanno
信州医学雑誌, 66(3), 195-204, 10 Jun. 2018
- Histopathological findings of pregnancy-induced hypertension: histopathology of early-onset type reflects two-stage disorder theory
Tateishi, Ayako; Ohira, Satoshi; Yamamoto, Yoichiro; Kanno, Hiroyuki;
VIRCHOWS ARCHIV, 472(4), 635-642, Apr. 2018 - In vasculitis of small muscular arteries, activation of vessel-infiltrating CD8 T cells seems to be antigen-independent.
Kobayashi M, Ogawa E, Okuyama R, Kanno H
Virchows Archiev, 472(2), 271, 2018 - Impact of the genetic variants of GLCC11 on clinical features of asthmatic patients.
Chiba S, Nakamura Y, Mizuno T, Abe K, Horii Y, Nagashima H, Sasaki N, Kanno H, Tanita T, Yamauchi K.
Clinical Respiratory Journal, 12(3), 1166, 2018 - Acquired amegakaryocytic thrombocytopenia with autoantibodies to thrombopoietin receptor (c-Mpl) in a patient with hepatitis C virus infection.
Ichimata S, Kobayashi M, Honda K, Shibata S, Matsumoto A, Kanno H.
WORLD JOURNAL OF GASTROENTEROLOGY, 23(35), 6540, 2017 - Quantitative diagnosis of breast tumors by morphometric classification of microenvironmental myoepithelial cells using a machine learning approach.
Yamamoto Y, Saito A, Tateishi A, Shimojo H, Kanno H, Tsuchiya S, Ito K, Cosatto E, Graf HP, Moraleda RR, Elis R, Grabe N.
SCIENTIFIC REPORTS, 7, 46732, 2017 - Tumor and immune cell dynamics explain the PSA bounce after prostate cancer brachytherapy
7. Yamamoto Y, Offord CP, Kimura G, Kuribayashi S, Takeda H, Tsuchiya S, Shimojo H, Kanno H, Bozic I, Nowak M, Bajzer Z, Dingli D
BRITISH JOURNAL OF CANCER, 115, 195-202, 2016 - Therapeutic implication of genetic variants of IL13 and STAT4 in airway remodelling with bronchial asthma
6. Nakamura Y, Suzuki R, Mizuno T, Abe K, Chiba S, Horii Y, Tsuboi J, Ito S, Obara W, Tanita T, Kanno H, Yamauchi K
Clinical and Experimental Allergy, 46(9), 1152-1161, 2016 - Axonal TDP-43 aggregates in sporadic amyotrophic lateral sclerosis.
Onozato T, Nakahara A, Suzuki-Kouyama E, Hineno A, Yasuda T, Nakamura T, Yahikozawa H, Watanabe M, Kayanuma K, Makishita H, Ohara S, Hashimoto T, Higuchi K, Sakai T, AsanoK, Hashimoto T, Kanno H, Nakayama J, Oyanagi K.
Neuropathol. Appl. Neurobiol., 42(6), 561-572, 2016 - Late-onset rejection of a unilateral donor lung with vascular C4d deposition in bilateral living-donor lobar lung transplantation: An autopsy case report.
Yamamoto H, Yoshida K, Koizumi T, Tokoro Y, Fukushima T, Tateishi K, Ushiki A, Yokoyama T, Yasuo M, Urushihara K, Hanaoka M, Shingu K, Shimojo H, Kanno H, Yoshizawa A, Kawakami S, Miyagawa-Hayashino A, Date H, Kubo K
Intern Medicine, 53, 1645-1650, 2014 - Polymyxins as novel and safe mucosal adjuvants to induce humoral immune responses in mice.
6. Yoshino, N., Endo, M., Kanno, H., Matsukawa, N., Tsutsumi, R., Takeshita, R., and Sato, S.
PLOS ONE, 8, e61643, 2013 - World’s first telepathology experiments employing ultra-high-speed internet satellite, nicknamed “KIZUNA”.
5. Sawai, T., Uzuki, M., Miura, Y., Kamataki, A., Matsumura, T., Saito, K., Kurose, A., Osamura, Y. R., Yoshimi, N., Kanno, H., Moriya, T., Ishida, Y., Satoh, Y., Nakao, M., Ogawa, E., Matsuo, S., Kasai, H., Kumagai, K., Motoda, T., and Hopson, N.
Journal of Pathology Informatics, 4, 24, 2013 - Mucosal immune responses in W/Wv and Sl/Sld munant mice.
Yoshino, N., Kanno, H., Takahashi, K., Endo, M., and Sato, S.
EXPERIMENTAL ANIMALS, 61(4), 407-416, 2012 - Prospective randomized controlled study comparing cell block method and conventional smear method for pancreatic juice cytology.
Noda Y, Fujita N, Kobayashi G, Ito K, Horaguchi J, Obana T, Koshita S, Kanno Y, Yamashita Y, Kato Y, Ogawa T, Tsuchiya T, Oikawa M, Sawai T, Kanno H, and Kurose A.
DIGESTIVE ENDOSCOPY, 24(3), 168-174, 2012 - Systemic sclerosis presented as congestive heart failure: an autopsy case.
Kanno, H., Segawa, T., Miura, Y., Miyata, M., Yoshida, A., Nakamura, M., and Sawai, T.
Modern Rheumatol., 21(4), 423-427, 2011 - Effect of genetic variation of IL-13 on airway remodeling in bronchial asthma.
Nagashima, H., Nakamura, Y., Kanno, H., Sawai, T., Inoue, H., and Yamauchi, K.
ALLERGOLOGY INTERNATIONAL, 60(3), 291-298, 2011
Lectures, oral presentations, etc.
- スポンサードシンポジウム６：補体と免疫疾患-基礎から最新治療薬まで：ANCA関連血管炎・腎炎の病理
菅野祐幸
第37回日本臨床リウマチ学会, 29 Oct. 2022Heavy chain amyloidosis in gastroduodenal biopsies-the histopathological features-
Ichimata S, Kobayashi M, Shimojo H, Katoh N, Yazaki M, Kanno H.
XVIth International Symposium on Amyloidosis, 27 Mar. 2018, Not invitedPredominant infiltration of CD8 T cells activated in antigen-independent manner in vasculitis of small muscular arteries.
Kobayashi, M., Ogawa, E., Okuyama, R., and Kanno, H.
18th International Vasculitis and ANCA Workshop: Diversity and Integration for Tomorrow, 25 Mar. 2017, Not invitedIntestinal Ischemia due to vasculitis following the reactivation of Epstein-Barr virus infection.
Ichimata, S., Ishigame, H., Mitsuishi, T., Yamamoto, K., and Kanno, H
18th International Vasculitis and ANCA Workshop: Diversity and Integration for Tomorrow, 25 Mar. 2017, Not invitedIncreased adhesion of Epstein-Berr virus-encoded small RNA-expressing T cells to cultured endothelial cells.
Kanno, H., and Sawai, T.
The Asia Paciffic meeting of vasculitis and ANCA workshop 2012, 29 Mar. 2012, Not invitedAffiliated academic society
Educational activity information