Paper

• Role of G Protein-coupled Receptor Signaling in Systemic Energy Homeostasis
  KIMURA Takefumi
  The Shinshu Medical Journal, 70(4), 213-223, Aug. 2022
• Expression and Role of beta 3-Adrenergic Receptor during the Differentiation of 3T3-L1 Preadipocytes into Adipocytes
  Roshanzadeh, Amir; Yadav, Anil Kumar; Pydi, Sai-Prasad; Kimura, Takefumi; Jang, Byeong-Churl;
  BIOLOGY-BASEL, 11(5), 772, May 2022
• 2-Step PLT16-AST44 method: Simplified liver fibrosis detection system in patients with non-alcoholic fatty liver disease
  Fujimori, Naoyuki; Kimura, Takefumi; Tanaka, Naoki; Yamazaki, Tomoo; Okumura, Taiki; Kobayashi, Hiroyuki; Wakabayashi, Shun-Ichi; Yamashita, Yuki; Sugiura, Ayumi; Pham, Jonathan; Pydi, Sai P.; Sano, Kenji; Joshita, Satoru; Umemura, Takeji;
  HEPATOLOGY RESEARCH, 52(4), 352-363, Apr. 2022
• Adipocyte G(q) signaling is a regulator of glucose and lipid homeostasis in mice
  Kimura, Takefumi; Pydi, Sai P.; Wang, Lei; Haspula, Dhanush; Cui, Yinghong; Lu, Huiyan; Koenig, Gabriele M.; Kostenis, Evi; Steinberg, Gregory R.; Gavrilova, Oksana; Wess, Juergen;
  NATURE COMMUNICATIONS, 13(1), 1652, 2022
• Acidic Activated Charcoal Prevents Obesity and Insulin Resistance in High-Fat Diet-Fed Mice
  Zhang, Xuguang; Diao, Pan; Yokoyama, Hiroaki; Inoue, Yoshiki; Tanabe, Kazuhiro; Wang, Xiaojing; Hayashi, Chihiro; Yokoyama, Tomoki; Zhang, Zhe; Hu, Xiao; Nakajima, Takero; Kimura, Takefumi; Nakayama, Jun; Nakamuta, Makoto; Tanaka, Naoki;
  Frontiers in Nutrition, 9, 852767, 2022
• Mechanisms of Steatosis-Derived Hepatocarcinogenesis: Lessons from HCV Core Gene Transgenic Mice
  Diao, Pan; Jia, Fangping; Wang, Xiaojing; Hu, Xiao; Kimura, Takefumi; Nakajima, Takero; Aoyama, Toshifumi; Moriya, Kyoji; Koike, Kazuhiko; Tanaka, Naoki;
  ENGINEERING, 7(12), 1797-1805, Dec. 2021
• Impact of Dietary Fat on the Progression of Liver Fibrosis: Lessons from Animal and Cell Studies
  Jia, Fangping; Hu, Xiao; Kimura, Takefumi; Tanaka, Naoki;
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(19), 10303, Oct. 2021
• Receptor-Mediated Gq Signaling in Adipocytes as a Critical Modulator of Systemic Glucose and Lipid Homeostasis
  Kimura, Takefumi; Pydi, Sai Prasad; Wang, Lei; Cui, Yinghong; Gavrilova, Oksana; Wess, Jurgen;
  DIABETES, 70, Jun. 2021
• G(q) signaling in adipocytes is a key regulator of systemic glucose and lipid homeostasis
  Kimura, Takefumi; Pydi, Sai; Wang, Lei; Cui, Yinghong; Gavrilova, Oksana; Wess, Jurgen;
  FASEB JOURNAL, 35, May 2021
• Metabolic roles of G protein-coupled receptor signaling in obesity and type 2 diabetes
  Barella, Luiz F.; Jain, Shanu; Kimura, Takefumi; Pydi, Sai P.;
  FEBS JOURNAL, 288(8), 2622-2644, Apr. 2021
• Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD
  Kimura, Takefumi; Tanaka, Naoki; Fujimori, Naoyuki; Yamazaki, Tomoo; Katsuyama, Takahito; Iwashita, Yuichi; Pham, Jonathan; Joshita, Satoru; Pydi, Sai P.; Umemura, Takeji;
  LIVER INTERNATIONAL, 41(3), 505-514, Mar. 2021
• Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic Treatment of Non-Alcoholic Fatty Liver Disease
  Kimura, Takefumi; Singh, Simran; Tanaka, Naoki; Umemura, Takeji;
  FRONTIERS IN ENDOCRINOLOGY, 12, 773432, 2021
• Susceptibility of the obese population to COVID-19
  Kimura, Takefumi; Namkoong, Ho;
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 101, 380-381, Dec. 2020
• A saturated fatty acid-rich diet enhances hepatic lipogenesis and tumorigenesis in HCV core gene transgenic mice
  Diao, Pan; Wang, Xiaojing; Jia, Fangping; Kimura, Takefumi; Hu, Xiao; Shirotori, Saki; Nakamura, Ibuki; Sato, Yoshiko; Nakayama, Jun; Moriya, Kyoji; Koike, Kazuhiko; Gonzalez, Frank J.; Aoyama, Toshifumi; Tanaka, Naoki;
  Journal of Nutritional Biochemistry, 85, 108460, Nov. 2020
• Metabolic Functions of G Protein-Coupled Receptors in Hepatocytes-Potential Applications for Diabetes and NAFLD
  Kimura, Takefumi; Pydi, Sai P.; Pham, Jonathan; Tanaka, Naoki;
  BIOMOLECULES, 10(10), 1445, Oct. 2020
• Acute liver failure with severe steatosis induced by mushroom
  Wakabayashi, Shun-ichi; Kimura, Takefumi; Tanaka, Naoki;
  LIVER INTERNATIONAL, 40(9), 2291-2292, Sep. 2020
• Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice
  Jia, Fangping; Diao, Pan; Wang, Xiaojing; Hu, Xiao; Kimura, Takefumi; Nakamuta, Makoto; Nakamura, Ibuki; Shirotori, Saki; Sato, Yoshiko; Moriya, Kyoji; Koike, Kazuhiko; Gonzalez, Frank J.; Nakayama, Jun; Aoyama, Toshifumi; Tanaka, Naoki;
  Liver Cancer, 9(5), 529-548, Sep. 2020
• Activation of Adipocyte Gq Signaling Causes Improved Whole-Body Glucose Homeostasis
  Kimura, Takefumi; Pydi, Sai Prasad; Wang, Lei; Cui, Yinghong; Gavrilova, Oksana; Wess, Jurgen;
  DIABETES, 69, Jun. 2020
• Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases
  Sugiura, Ayumi; Joshita, Satoru; Yamashita, Yuki; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Wada, Shuichi; Mori, Hiromitsu; Shibata, Soichiro; Yoshizawa, Kaname; Morita, Susumu; Furuta, Kiyoshi; Kamijo, Atsushi; Iijima, Akihiro; Kako, Satoko; Maruyama, Atsushi; Kobayashi, Masakazu; Komatsu, Michiharu; Matsumura, Makiko; Miyabayashi, Chiharu; Ichijo, Tetsuya; Takeuchi, Aki; Koike, Yuriko; Gibo, Yukio; Tsukadaira, Toshihisa; Inada, Hiroyuki; Nakano, Yoshiyuki; Usuda, Seiichi; Kiyosawa, Kendo; Tanaka, Eiji; Umemura, Takeji;
  BIOMEDICINES, 8(4), 74, Apr. 2020
• A trans-fatty acid-rich diet promotes liver tumorigenesis in HCV core gene transgenic mice
  Hu, Xiao; Wang, Xiaojing; Jia, Fangping; Tanaka, Naoki; Kimura, Takefumi; Nakajima, Takero; Sato, Yoshiko; Moriya, Kyoji; Koike, Kazuhiko; Gonzalez, Frank J.; Nakayama, Jun; Aoyama, Toshifumi;
  CARCINOGENESIS, 41(2), 159-170, Feb. 2020
• What will happen in patients with advanced nonalcoholic fatty liver disease?
  Kimura, Takefumi; Tanaka, Naoki; Tanaka, Eiji;
  HEPATOBILIARY SURGERY AND NUTRITION, 8(3), 283-285, Jun. 2019
• A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice (vol, pg, )
  Wang, Xiaojing; Tanaka, Naoki; Hu, Xiao; Kimura, Takefumi; Lu, Yu; Jia, Fangping; Sato, Yoshiko; Nakayama, Jun; Moriya, Kyoji; Koike, Kazuhiko; Aoyama, Toshifumi;
  ARCHIVES OF TOXICOLOGY, 93(6), 1727-1728, Jun. 2019
• A high-cholesterol diet promotes steatohepatitis and liver tumorigenesis in HCV core gene transgenic mice
  Wang, Xiaojing; Tanaka, Naoki; Hu, Xiao; Kimura, Takefumi; Lu, Yu; Jia, Fangping; Sato, Yoshiko; Nakayama, Jun; Moriya, Kyoji; Koike, Kazuhiko; Aoyama, Toshifumi;
  ARCHIVES OF TOXICOLOGY, 93(6), 1713-1725, Jun. 2019
• Red plasma and ascites under ultraviolet A
  Wakabayashi, Shun-ichi; Kimura, Takefumi; Tanaka, Naoki; Komatsu, Michiharu; Tanaka, Eiji;
  LANCET GASTROENTEROLOGY & HEPATOLOGY, 4(4), 324-324, Apr. 2019
• Current status, problems, and perspectives of non-alcoholic fatty liver disease research
  Tanaka, Naoki; Kimura, Takefumi; Fujimori, Naoyuki; Nagaya, Tadanobu; Komatsu, Michiharu; Tanaka, Eiji;
  WORLD JOURNAL OF GASTROENTEROLOGY, 25(2), 163-177, 2019
• Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals
  Sugiura, Ayumi; Joshita, Satoru; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Usami, Yoko; Wada, Shuichi; Mori, Hiromitsu; Shibata, Soichiro; Yoshizawa, Kaname; Morita, Susumu; Furuta, Kiyoshi; Kamijo, Atsushi; Iijima, Akihiro; Kako, Satoko; Maruyama, Atsushi; Kobayashi, Masakazu; Komatsu, Michiharu; Matsumura, Makiko; Miyabayashi, Chiharu; Ichijo, Tetsuya; Takeuchi, Aki; Koike, Yuriko; Gibo, Yukio; Tsukadaira, Toshihisa; Inada, Hiroyuki; Kiyosawa, Kendo; Tanaka, Eiji;
  JOURNAL OF VIRAL HEPATITIS, 25(12), 1462-1471, Dec. 2018
• Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients
  Komatsu, Michiharu; Tanaka, Naoki; Kimura, Takefumi; Fujimori, Naoyuki; Sano, Kenji; Horiuchi, Akira; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 48(13), 1092-1098, Dec. 2018
• THE RELATIONSHIP BETWEEN SERUM AUTOTAXIN LEVELS AND LIVER HISTOLOGICAL FINDINGS IN PATIENT WITH NON-ALCOHOLIC FATTY LIVER DISEASE
  Fujimori, Naoyuki; Kimura, Takefumi; Tanaka, Naoki;
  GASTROENTEROLOGY, 154(6), S1171-S1171, May 2018
• Two Cases of Primary Biliary Cholangitis with Hepatocellular Carcinoma in a Non-cirrhotic Stage
  SUGIURA Ayumi, JOSHITA Satoru, YAMASHITA Yuki, KIMURA Takefumi, YAMAZAKI Tomoo, FUJIMORI Naoyuki, KOMATSU Michiharu, MATSUMOTO Akihiro, KOBAYASHI Shota, UMEMURA Takeji, TANAKA Eiji
  The Shinshu Medical Journal, 66(1), 39-49, Feb. 2018
• Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis
  Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Yamashita, Yuki; Norman, Gary L.; Sugiura, Ayumi; Yamazaki, Tomoo; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Yoshizawa, Kaname; Ota, Masao; Tanaka, Eiji;
  SCIENTIFIC REPORTS, 8, 8159, 2018
• Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C
  Yamazaki, Tomoo; Joshita, Satoru; Umemura, Takeji; Usami, Yoko; Sugiura, Ayumi; Fujimori, Naoyuki; Kimura, Takefumi; Matsumoto, Akihiro; Igarashi, Koji; Ota, Masao; Tanaka, Eiji;
  PLOS ONE, 13(4), e0195632, 2018
• Hepatic Angiosarcoma with Kasabach-Merritt Phenomenon: A Case Report and Review of the Literature
  Fujii, Fumika; Kimura, Takefumi; Tanaka, Naoki; Kubota, Daisuke; Sugiura, Ayumi; Umemura, Takeji; Wada, Shuichi; Tanaka, Eiji;
  ANNALS OF HEPATOLOGY, 17(4), 655-660, 2018
• Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis
  Kimura, Takefumi; Tanaka, Naoki; Fujimori, Naoyuki; Sugiura, Ayumi; Yamazaki, Tomoo; Joshita, Satoru; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
  WORLD JOURNAL OF GASTROENTEROLOGY, 24(13), 1440-1450, 2018
• Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease
  Fujimori, Naoyuki; Umemura, Takeji; Kimura, Takefumi; Tanaka, Naoki; Sugiura, Ayumi; Yamazaki, Tomoo; Joshita, Satoru; Komatsu, Michiharu; Usami, Yoko; Sano, Kenji; Igarashi, Koji; Matsumoto, Akihiro; Tanaka, Eiji;
  WORLD JOURNAL OF GASTROENTEROLOGY, 24(11), 1239-1249, 2018
• Two cases of non-cirrhotic primary biliary cirrhosis with complicating hepatocellular carcinoma
  Sugiura, Ayumi; Joshita, Satoru; Yamashita, Yuki; Hihara, Yu; Fujimori, Naoyuki; Yamazaki, Tomoo; Maruyama, Yasuhiro; Shibata, Souichiro; Ichikawa, Yuki; Kimura, Takefumi; Ito, Tetsuya; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 32, 186-186, Sep. 2017
• Association between lower air pressure and the onset of ischemic colitis: a case-control study
  Kimura, Takefumi; Shinji, Akihiro; Tanaka, Naoki; Koinuma, Masayoshi; Yamaura, Maki; Nagaya, Tadanobu; Joshita, Satoru; Komatsu, Michiharu; Umemura, Takeji; Horiuchi, Akira; Wada, Shuichi; Tanaka, Eiji;
  EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 29(9), 1071-1078, Sep. 2017
• ASSOCIATION BETWEEN LOWER AIR PRESSURE AND THE ONSET OF ISCHEMIC COLITIS: A NOVEL METEOROLOGICAL ASPECT
  Kimura, Takefumi; Tanaka, Naoki;
  GASTROENTEROLOGY, 152(5), S945-S945, Apr. 2017
• Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection
  Kimura, Takefumi; Kobayashi, Akira; Tanaka, Naoki; Sano, Kenji; Komatsu, Michiharu; Fujimori, Naoyuki; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Horiuchi, Akira; Mori, Hiromitsu; Wada, Shuichi; Kiyosawa, Kendo; Miyagawa, Shin-ichi; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 47(5), 405-418, Apr. 2017
• Vonoprazan-Based Regimen Is More Useful than PPI-Based One as a First-Line Helicobacter pylori Eradication: A Randomized Controlled Trial
  Maruyama, Masafumi; Tanaka, Naoki; Kubota, Daisuke; Miyajima, Masayuki; Kimura, Takefumi; Tokutake, Koujiro; Imai, Ryujiro; Fujisawa, Toru; Mori, Hiromitsu; Matsuda, Yoshiaki; Wada, Shuichi; Horiuchi, Akira; Kiyosawa, Kendo;
  CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 4385161, 2017
• Association between endotoxemia and histological features of nonalcoholic fatty liver disease
  Kitabatake, Hiroyuki; Tanaka, Naoki; Fujimori, Naoyuki; Komatsu, Michiharu; Okubo, Ayaka; Kakegawa, Kyogo; Kimura, Takefumi; Sugiura, Ayumi; Yamazaki, Tomoo; Shibata, Soichiro; Ichikawa, Yuki; Joshita, Satoru; Umemura, Takeji; Matsumoto, Akihiro; Koinuma, Masayoshi; Sano, Kenji; Aoyama, Toshifumi; Tanaka, Eiji;
  WORLD JOURNAL OF GASTROENTEROLOGY, 23(4), 712-722, 2017
• Controlled attenuation parameter is correlated with actual hepatic fat content in patients with non-alcoholic fatty liver disease with none-to-mild obesity and liver fibrosis
  Fujimori, Naoyuki; Tanaka, Naoki; Shibata, Soichiro; Sano, Kenji; Yamazaki, Tomoo; Sekiguchi, Tomohiro; Kitabatake, Hiroyuki; Ichikawa, Yuki; Kimura, Takefumi; Komatsu, Michiharu; Umemura, Takeji; Matsumoto, Akihiro; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 46(10), 1019-1027, Sep. 2016
• Liver stiffness-spleen size-to-platelet ratio risk score identifies esophageal varices in Japanese patients with chronic hepatitis C
  Shibata, Soichiro; Umemura, Takeji; Yamazaki, Tomoo; Fujimori, Naoyuki; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 46(9), 884-889, Aug. 2016
• A Randomized Controlled Trial Comparing the First-Line Eradication Rate Using Vonoprazan or PPI for Helicobacter pylori Infectious Gastritis
  Maruyama, Masafumi; Kubota, Daisuke; Miyajima, Masayuki; Kimura, Takefumi; Tokutake, Koujiro; Imai, Ryujiro; Fujisawa, Toru; Mori, Hiromitsu; Matsuda, Yoshiaki; Wada, Shuichi; Kiyosawa, Kendo;
  GASTROENTEROLOGY, 150(4), S1269-S1269, Apr. 2016
• Primary hepatocellular carcinoma in a patient with neurofibromatosis type I
  Kimura, Takefumi; Tanaka, Naoki; Umemura, Takeji; Tanaka, Eiji;
  LIVER INTERNATIONAL, 35(8), 2057-2058, Aug. 2015
• Serum sodium concentration is associated with increased risk of mortality in patients with compensated liver cirrhosis
  Umemura, Takeji; Shibata, Soichiro; Sekiguchi, Tomohiro; Kitabatake, Hiroyuki; Nozawa, Yuichi; Okuhara, Sadahisa; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 45(7), 739-744, Jul. 2015
• Serum Wisteria floribunda Agglutinin-Positive Mac-2-Binding Protein Level Predicts Liver Fibrosis and Prognosis in Primary Biliary Cirrhosis
  Umemura, Takeji; Joshita, Satoru; Sekiguchi, Tomohiro; Usami, Yoko; Shibata, Soichiro; Kimura, Takefumi; Komatsu, Michiharu; Matsumoto, Akihiro; Ota, Masao; Tanaka, Eiji;
  AMERICAN JOURNAL OF GASTROENTEROLOGY, 110(6), 857-864, Jun. 2015
• Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPAR alpha
  Komatsu, Michiharu; Kimura, Takefumi; Yazaki, Masahide; Tanaka, Naoki; Yang, Yang; Nakajima, Takero; Horiuchi, Akira; Fang, Zhong-Ze; Joshita, Satoru; Matsumoto, Akihiro; Umemura, Takeji; Tanaka, Eiji; Gonzalez, Frank J.; Ikeda, Shu-Ichi; Aoyama, Toshifumi;
  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1852(3), 473-481, Mar. 2015
• Serum Cell Death Biomarkers for Prediction of Liver Fibrosis and Poor Prognosis in Primary Biliary Cirrhosis
  Sekiguchi, Tomohiro; Umemura, Takeji; Fujimori, Naoyuki; Shibata, Soichiro; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji; Ota, Masao;
  PLOS ONE, 10(6), e0131658, 2015
• Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion
  Kamijo, Nozomi; Matsumoto, Akihiro; Umemura, Takeji; Shibata, Soichiro; Ichikawa, Yuki; Kimura, Takefumi; Komatsu, Michiharu; Tanaka, Eiji;
  WORLD JOURNAL OF GASTROENTEROLOGY, 21(2), 541-548, 2015
• Characteristics and prediction of hepatitis B e-antigen negative hepatitis following seroconversion in patients with chronic hepatitis B
  Morita, Susumu; Matsumoto, Akihiro; Umemura, Takeji; Shibata, Soichiro; Kamijo, Nozomi; Ichikawa, Yuki; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Yoshizawa, Kaname; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 44(10), E45-E53, Oct. 2014
• Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B
  Okuhara, Sadahisa; Umemura, Takeji; Joshita, Satoru; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Katsuyama, Yoshihiko; Ota, Masao; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 44(10), E172-E180, Oct. 2014
• KIR3DL1-HLA-Bw4 combination and IL28B polymorphism predict response to Peg-IFN and ribavirin with and without telaprevir in chronic hepatitis C
  Umemura, Takeji; Ota, Masao; Katsuyama, Yoshihiko; Wada, Shuichi; Mori, Hiromitsu; Maruyama, Atsushi; Shibata, Soichiro; Nozawa, Yuichi; Kimura, Takefumi; Morita, Susumu; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Kamijo, Atsushi; Kobayashi, Masakazu; Takamatsu, Masato; Yoshizawa, Kaname; Kiyosawa, Kendo; Tanaka, Eiji;
  HUMAN IMMUNOLOGY, 75(8), 822-826, Aug. 2014
• Laparoscopic findings of congenital hepatic fibrosis: A case report and review of the published work
  Komatsu, Michiharu; Tanaka, Naoki; Shibata, So-Ichirou; Kimura, Takefumi; Ichikawa, Yuki; Morita, Susumu; Joshita, Satoru; Nagaya, Tadanobu; Umemura, Takeji; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Tanaka, Eiji;
  HEPATOLOGY RESEARCH, 44(7), 818-824, Jul. 2014
• Natural History and Prognosis of Asymptomatic and Symptomatic Japanese Patients With Primary Biliary Cirrhosis: Results of a Median 9-Year Follow-Up Study
  Joshita, Satoru; Umemura, Takeji; Nozawa, Yuichi; Okuhara, Sadahisa; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Ota, Masao; Tanaka, Eiji;
  GASTROENTEROLOGY, 146(5), S906-S906, May 2014
• Human Leukocyte Antigen Class II Haplotypes Affect Clinical Characteristics and Progression of Type 1 Autoimmune Hepatitis in Japan
  Umemura, Takeji; Katsuyama, Yoshihiko; Yoshizawa, Kaname; Kimura, Takefumi; Joshita, Satoru; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji; Ota, Masao;
  PLOS ONE, 9(6), e100565, 2014
• Steatogenesis in adult-onset type II citrullinemia is associated with down-regulation of PPAR alpha
  Kimura, Takefumi;
  Hepatology, 60, 819A-819A, 2014
• STAT4 Gene Polymorphisms Are Associated with Susceptibility and ANA Status in Primary Biliary Cirrhosis
  Joshita, Satoru; Umemura, Takeji; Nakamura, Minoru; Katsuyama, Yoshihiko; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Ishibashi, Hiromi; Tanaka, Eiji; Ota, Masao;
  DISEASE MARKERS, 2014, 727393, 2014
• Peroxisome proliferator-activated receptor alpha mediates enhancement of gene expression of cerebroside sulfotransferase in several murine organs
  Nakajima, Takero; Kamijo, Yuji; Huang Yuzhe; Kimura, Takefumi; Tanaka, Naoki; Sugiyama, Eiko; Nakamura, Kozo; Kyogashima, Mamoru; Hara, Atsushi; Aoyama, Toshifumi;
  GLYCOCONJUGATE JOURNAL, 30(6), 553-560, Aug. 2013
• Cutaneous sarcoidosis in a chronic hepatitis C patient receiving pegylated interferon and ribavirin therapy
  Joshita, Satoru; Shirahata, Kumiko; Yazaki, Yoshikazu; Okaniwa, Shinji; Nakamura, Yoshiyuki; Kimura, Takefumi; Noami, Sugiko; Horigome, Reiko; Yagi, Hikaru; Ito, Nobuo; Yamazaki, Asami; Akahane, Yuki; Umemura, Takeji; Yoshizawa, Kaname; Tanaka, Eiji; Ota, Masao;
  HEPATOLOGY RESEARCH, 43(7), 801-807, Jul. 2013
• Association analysis of toll-like receptor 4 polymorphisms in Japanese primary biliary cirrhosis
  Morita, Susumu; Joshita, Satoru; Umemura, Takeji; Katsuyama, Yoshihiko; Kimura, Takefumi; Komatsu, Michiharu; Matsumoto, Akihiro; Yoshizawa, Kaname; Kamijo, Astushi; Yamamura, Nobuyoshi; Tanaka, Eiji; Ota, Masao;
  HUMAN IMMUNOLOGY, 74(2), 219-222, Feb. 2013
• KIR, HLA, and IL28B Variant Predict Response to Antiviral Therapy in Genotype 1 Chronic Hepatitis C Patients in Japan
  Nozawa, Yuichi; Umemura, Takeji; Joshita, Satoru; Katsuyama, Yoshihiko; Shibata, Soichiro; Kimura, Takefumi; Morita, Susumu; Komatsu, Michiharu; Matsumoto, Akihiro; Tanaka, Eiji; Ota, Masao;
  PLOS ONE, 8(12), e83381, 2013
• Clinical Characteristics of Young-Onset Ischemic Colitis
  Kimura, Takefumi; Shinji, Akihiro; Horiuchi, Akira; Tanaka, Naoki; Nagaya, Tadanobu; Shigeno, Takashi; Nakamura, Naoshi; Komatsu, Michiharu; Umemura, Takeji; Arakura, Norikazu; Matsumoto, Akihiro; Tanaka, Eiji;
  DIGESTIVE DISEASES AND SCIENCES, 57(6), 1652-1659, Jun. 2012
• Hepatic Cerebroside Sulfotransferase is Induced by PPAR alpha Activation in Mice
  Kimura, Takefumi; Nakajima, Takero; Tanaka, Naoki; Komatsu, Michiharu; Kamijo, Yuji; Tanaka, Eiji; Aoyama, Toshifumi;
  GASTROENTEROLOGY, 142(5), S988-S988, May 2012
• Association of IL28B gene polymorphism with development of hepatocellular carcinoma in Japanese patients with chronic hepatitis C virus infection
  Joshita, Satoru; Umemura, Takeji; Katsuyama, Yoshihiko; Ichikawa, Yuki; Kimura, Takefumi; Morita, Susumu; Kamijo, Atsushi; Komatsu, Michiharu; Ichijo, Tetsuya; Matsumoto, Akihiro; Yoshizawa, Kaname; Kamijo, Nozomi; Ota, Masao; Tanaka, Eiji;
  HUMAN IMMUNOLOGY, 73(3), 298-300, Mar. 2012
• Fatty Acid Accumulation and Resulting PPAR alpha Activation in Fibroblasts due to Trifunctional Protein Deficiency
  Wakabayashi, Masato; Kamijo, Yuji; Nakajima, Takero; Tanaka, Naoki; Sugiyama, Eiko; Tian Yangyang; Kimura, Takefumi; Aoyama, Toshifumi;
  PPAR RESEARCH, 2012, 371691, 2012
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