KOBAYASHI NORIMOTO
School of Medicine Department of Pediatrics
Assistant Professor
Researcher Information
Research activity information
Paper
- Efficacy of tocilizumab for interstitial lung disease associated with polyarticular juvenile idiopathic arthritis
Maruyama Y, Shigemura T, Kobayashi N, Nakazawa Y.
Pediatr Int ., 64(1), e14737, Jan. 2022 - Clinical impact of myositis-specific autoantibodies on long-term prognosis of juvenile idiopathic inflammatory myopathies: multicentre study
Yamasaki Y, Kobayashi N, Akioka S, Yamazaki K, Takezaki S, Nakaseko H, Ohara A, Nishimura K, Nishida Y, Sato S, Kishi T, Hashimoto M, Mori M, Okazaki Y, Kuwana M, Ohta A.
Rheumatology (Oxford) ., 60(10), 4821-4831, Oct. 2021 - Clinical practice guidance for juvenile dermatomyositis (JDM) 2018-Update.
Kobayashi I, Akioka S, Kobayashi N, Iwata N, Takezaki S, Nakaseko H, Sato S, Nishida Y, Nozawa T, Yamasaki Y, Yamazaki K, Arai S, Nishino I, Mori M.
Mod Rheumatol., 30(3), 411-423, May 2020 - Clinical features and new diagnostic criteria for the syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis.
Takeuchi Y, Shigemura T, Kobayashi N, Nagumo H, Furumoto M, Ogasawara K, Fujii H, Takizawa M, Soga T, Matoba H, Masumoto J, Fukushima K, Migita K, Ojima T, Umeda Y, Agematsu K.
Int J Rheum Dis., 22(8), 1489-1497, Aug. 2019 - Mosaicism of an ELANE Mutation in an Asymptomatic Mother
Shigemura T, Kobayashi N, Agematsu K, Ohara O, Nakazawa Y.
J Clin Immunol., 39(1), 106-111, Jan. 2019 - Analysis of biomarker serum levels in IVIG and infliximab refractory Kawasaki disease patients.
Hachiya A, Kobayashi N, Matsuzaki S, Takeuchi Y, Akazawa Y, Shigemura T, Motoki N, Masumoto J, Agematsu K.
Clin Rheumatol., 37(7), 1937, 2018 - Characteristics and outcome of intractable vasculitis syndrome in children: Nation-wide survey in Japan.
Nakano N, Mori M, Umebayashi H, Iwata N, Kobayashi N, Masunaga K, Imagawa T, Murata T, Kinjo N, Nagai K, Miyoshi M, Takei S, Yokota S, Ishii E.
28(4), 697, 2018 - Heterozygous Mutations in OAS1 Cause Infantile-Onset Pulmonary Alveolar Proteinosis with Hypogammaglobulinemia.
Cho K, Yamada M, Agematsu K, Kanegane H, Miyake N, Ueki M, Akimoto T, Kobayashi N, Ikemoto S, Tanino M, Fujita A, Hayasaka I, Miyamoto S, Tanaka-Kubota M, Nakata K, Shiina M, Ogata K, Minakami H, Matsumoto N, Ariga T.
Am J Hum Genet., 102(3), 480, 2018 - Infliximab versus intravenous immunoglobulin for refractory Kawasaki disease: a phase 3, randomized, open-label, active-controlled, parallel-group, multicenter trial.
Mori M, Hara T, Kikuchi M, Shimizu H, Miyamoto T, Iwashima S, Oonishi T, Hashimoto K, Kobayashi N, Waki K, Suzuki Y, Otsubo Y, Yamada H, Ishikawa C, Kato T, Fuse S.
Sci Rep., 8(1), 2018 - A Pediatric Case of Relapsing-Remitting Multiple Sclerosis Onset following Varicella Zoster Ophthalmicus with Optic Neuritis.
Shiba N, Inaba Y, Motobayashi M, Nishioka M, Kawasaki Y, Noda S, Matsuura H, Kobayashi N, Matsuoka T, Nakamura A, Nakazawa Y.
Case Rep Pediatr, 2018 - Analysis of serum IL-38 in juvenile-onset systemic lupus erythematosus. Agematsu K.
Takeuchi Y, Seki T, Kobayashi N, Sano K, Shigemura T, Shimojo H, Matsumoto K, Agematsu K.
Mod Rheumatol., 2018 - Early diagnosis of early-onset sarcoidosis: a case report with functional analysis and review of the literature.
Takeuchi Y, Shigemura T, Kobayashi N, Kaneko N, Iwasaki T, Minami K, Kobayashi K, Masumoto J, Agematsu K.
Clin Rheumatol., 36(5), 1189, 2017, Refereed - IFR4/MUM1-positive lymphoma in Waldeyer ring with co-expression of CD5 and CD10.
Chen L, Al-Kzayer LF, Liu T, Kobayashi N, Nakazawa Y, Koike K.
Pediatr Blood Cancer, 64(2), 311, 2017, Refereed - Acute Myeloid Leukemia in a Patient With X-linked Severe Combined Immunodeficiency.
Shigemura T, Motobayashi M, Matsuda K, Shimodaira T, Kurata T, Kobayashi N, Agematsu K, Nakazawa Y.
J Pediatr Hematol Oncol., 2017, Refereed - Markedly elevated CD64 expression on neutrophils and monocytes as a biomarker for diagnosis and therapy assessment in Kawasaki disease
Hokibara, Sho; Kobayashi, Norimoto; Kobayashi, Keiko; Shigemura, Tomonari; Nagumo, Haruo; Takizawa, Masahiro; Yamazaki, Takashi; Agematsu, Kazunaga;
INFLAMMATION RESEARCH, 65(7), 579-585, Jul. 2016
- Immune Complex-Mediated Glomerulonephritis in a Patient with Wiskott-Aldrich Syndrome
Shigemura, Tomonari; Nakazawa, Yozo; Shimojo, Hisashi; Kobayashi, Norimoto; Agematsu, Kazunaga;
JOURNAL OF CLINICAL IMMUNOLOGY, 36(4), 357-359, May 2016 - A novel surfactant protein C L55F mutation associated with interstitial lung disease alters subcellular localization of proSP-C in A549 cells
Liu, Tingting; Sano, Kenji; Ogiwara, Naoko; Kobayashi, Norimoto;
PEDIATRIC RESEARCH, 79(1), 27-33, Jan. 2016 - Novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal-dominant Behçet's disease.
Shigemura T, Kaneko N, Kobayashi N, Kobayashi K, Takeuchi Y, Nakano N, Masumoto J, Agematsu K.
RMD open, 2(1), 2016, Refereed - IL-18 serum concentration is markedly elevated in typical familial Mediterranean fever with M694I mutation and can distinguish it from atypical type
Yamazaki, Takashi; Shigemura, Tomonari; Kobayashi, Norimoto; Honda, Kimiko; Yazaki, Masahide; Masumoto, Junya; Migita, Kiyoshi; Agematsu, Kazunaga;
MODERN RHEUMATOLOGY, 26(2), 315-317, 2016 - Increased Serum B Cell Activating Factor and a Proliferation-inducing Ligand Are Associated with Interstitial Lung Disease in Patients with Juvenile Dermatomyositis
Kobayashi, Norimoto; Kobayashi, Ichiro; Mori, Masaaki; Sato, Shinji; Iwata, Naomi; Shigemura, Tomonari; Agematsu, Kazunaga; Yokota, Shumpei; Koike, Kenichi;
JOURNAL OF RHEUMATOLOGY, 42(12), 2412-2418, Dec. 2015 - Cytomegalovirus Encephalitis in a Patient with Severe Combined Immunodeficiency
Motobayashi, Mitsuo; Shigemura, Tomonari; Tanaka, Miyuki; Kurata, Takashi; Kobayashi, Norimoto; Agematsu, Kazunaga; Amano, Yoshiro; Inaba, Yuji; Koike, Kenichi; Nakazawa, Yozo;
JOURNAL OF CLINICAL IMMUNOLOGY, 35(8), 689-691, Nov. 2015 - 若年性皮膚筋炎における間質性肺病変 (特集 小児リウマチ性疾患の最新治療) -- (その他の膠原病)
小林 法元;
小児科診療, 78(8), 1109-1114, Aug. 2015
- Clinical and laboratory features of fatal rapidly progressive interstitial lung disease associated with juvenile dermatomyositis
Kobayashi, Norimoto; Takezaki, Shunichiro; Kobayashi, Ichiro; Iwata, Naomi; Mori, Masaaki; Nagai, Kazushige; Nakano, Naoko; Miyoshi, Mari; Kinjo, Noriko; Murata, Takuji; Masunaga, Kenji; Umebayashi, Hiroaki; Imagawa, Tomoyuki; Agematsu, Kazunaga; Sato, Shinji; Kuwana, Masataka; Yamada, Masafumi; Takei, Shuji; Yokota, Shumpei; Koike, Kenichi; Ariga, Tadashi;
RHEUMATOLOGY, 54(5), 784-791, May 2015 - Clinical and laboratory features of fatal rapidly progressive interstitial lung disease associated with juvenile dermatomyositis
Kobayashi, Norimoto; Takezaki, Shunichiro; Kobayashi, Ichiro; Iwata, Naomi; Mori, Masaaki; Nagai, Kazushige; Nakano, Naoko; Miyoshi, Mari; Kinjo, Noriko; Murata, Takuji; Masunaga, Kenji; Umebayashi, Hiroaki; Imagawa, Tomoyuki; Agematsu, Kazunaga; Sato, Shinji; Kuwana, Masataka; Yamada, Masafumi; Takei, Shuji; Yokota, Shumpei; Koike, Kenichi; Ariga, Tadashi;
RHEUMATOLOGY, 54(5), 784-791, May 2015 - An Increase in Circulating B Cell-Activating Factor in Childhood-Onset Ocular Myasthenia Gravis
Motobayashi, Mitsuo; Inaba, Yuji; Nishimura, Takafumi; Kobayashi, Norimoto; Nakazawa, Yozo; Koike, Kenichi;
PEDIATRIC NEUROLOGY, 52(4), 404-409, Apr. 2015 - Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes
Nakagawa, Kenji; Gonzalez-Roca, Eva; Souto, Alejandro; Kawai, Toshinao; Umebayashi, Hiroaki; Maria Campistol, Josep; Canellas, Jeronima; Takei, Syuji; Kobayashi, Norimoto; Luis Callejas-Rubio, Jose; Ortego-Centeno, Norberto; Ruiz-Ortiz, Estibaliz; Rius, Fina; Anton, Jordi; Iglesias, Estibaliz; Jimenez-Trevino, Santiago; Vargas, Carmen; Fernandez-Martin, Julian; Calvo, Inmaculada; Hernandez-Rodriguez, Jose; Mendez, Maria; Teresa Dordal, Maria; Basagana, Maria; Bujan, Segundo; Yashiro, Masato; Kubota, Tetsuo; Koike, Ryuji; Akuta, Naoko; Shimoyama, Kumiko; Iwata, Naomi; Saito, Megumu K.; Ohara, Osamu; Kambe, Naotomo; Yasumi, Takahiro; Izawa, Kazushi; Kawai, Tomoki; Heike, Toshio; Yaguee, Jordi; Nishikomori, Ryuta; Arostegui, Juan I.;
ANNALS OF THE RHEUMATIC DISEASES, 74(3), 603-610, Mar. 2015 - Successful treatment for West syndrome with severe combined immunodeficiency
Motobayashi, Mitsuo; Inaba, Yuji; Fukuyama, Tetsuhiro; Kurata, Takashi; Niimi, Taemi; Saito, Shoji; Shiba, Naoko; Nishimura, Takafumi; Shigemura, Tomonari; Nakazawa, Yozo; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Ichikawa, Motoki; Koike, Kenichi;
BRAIN & DEVELOPMENT, 37(1), 140-144, Jan. 2015 - Dramatic Improvement in the Multifocal Positron Emission Tomography Findings of a Young Adult with Chronic Granulomatous Disease Following Allogeneic Hematopoietic Stem Cell Transplantation
Shigemura, Tomonari; Nakazawa, Yozo; Hirabayashi, Koichi; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Koike, Kenichi;
JOURNAL OF CLINICAL IMMUNOLOGY, 35(1), 84-86, Jan. 2015 - Dramatic Improvement in the Multifocal Positron Emission Tomography Findings of a Young Adult with Chronic Granulomatous Disease Following Allogeneic Hematopoietic Stem Cell Transplantation
Shigemura, Tomonari; Nakazawa, Yozo; Hirabayashi, Koichi; Kobayashi, Norimoto; Sakashita, Kazuo; Agematsu, Kazunaga; Koike, Kenichi;
JOURNAL OF CLINICAL IMMUNOLOGY, 35(1), 84-86, Jan. 2015 - Clinical Course in a Patient With Neutrophil-Specific Granule Deficiency and Rapid Detection of Neutrophil Granules as a Screening Test
Shigemura, Tomonari; Yamazaki, Takashi; Shiohara, Masaaki; Kobayashi, Norimoto; Naganuma, Kuniaki; Koike, Kenich; Agematsu, Kazunaga;
JOURNAL OF CLINICAL IMMUNOLOGY, 34(7), 780-783, Oct. 2014 - Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation
Shigemura, Tomonari; Nakazawa, Yozo; Matsuda, Kazuyuki; Sano, Kenji; Yaguchi, Takashi; Motobayashi, Mitsuo; Saito, Shoji; Noda, Shunsuke; Kobayashi, Norimoto; Agematsu, Kazunaga; Honda, Takayuki; Koike, Kenichi;
INTERNATIONAL JOURNAL OF HEMATOLOGY, 100(2), 206-209, Aug. 2014 - Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis
Shigemura, Tomonari; Nakazawa, Yozo; Yoshikawa, Kentaro; Hirabayashi, Koichi; Saito, Shoji; Kobayashi, Norimoto; Sakashita, Kazuo; Shiohara, Masaaki; Wada, Taizo; Shimodaira, Shigetaka; Agematsu, Kazunaga; Koike, Kenichi;
TRANSFUSION, 54(3), 516-521, Mar. 2014 - Clinical Utility of Anti-CADM-140/Melanoma Differentiation-Associated Gene 5 Autoantibody Titers in Patients with Juvenile Dermatomyositis and Rapidly Progressive Interstitial Lung Disease
Sato, Shinji; Kobayashi, Norimoto; Yamazaki, Kazuko; Suzuki, Yasuo;
ARTHRITIS AND RHEUMATISM, 64(10), S128-S128, Oct. 2012 - Food allergy after cord blood transplantation in children.
Sakashita K, Nakazawa Y, Yanagisawa R, Tanaka M, Saito S, Yoshikawa K, Hirabayashi K, Kusakari M, Kato S, Hidaka N, Nakayama Y, Shigemura T, Kobayashi N, Kobayashi M, Shiohara M, Koike K.
Br J Haematol, 158(5), 1365, Sep. 2012 - TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells.
Albacker LA, Karisola P, Chang YJ, Umetsu SE, Zhou M, Akbari O, Kobayashi N, Baumgarth N, Freeman GJ, Umetsu DT, DeKruyff RH.
J Immunol, 185(11), 6839-49, 2010 - Distinct response in maintenance of human naive and memory B cells via IL-21 receptor and TCL1/Akt pathways.
Nagumo H, Abe J, Kano H, Taki S, Yamazaki K, Yamazaki T, Kobayashi N, Koike K, Sugane K, Saito H, Agematsu K.
Cell Immunol, 256(1-2), 56, 2009 - TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells.
Kobayashi N, Karisola P, Peña-Cruz V, Dorfman DM, Jinushi M, Umetsu SE, Butte MJ, Nagumo H, Chernova I, Zhu B, Sharpe AH, Ito S, Dranoff G, Kaplan GG, Casasnovas JM, Umetsu DT, Dekruyff RH, Freeman GJ
Immunity, 27(6), 927-40, 2007 - Differential effects of short-acting beta(2)-agonists on human granulocyte functions
Yasui, K; Kobayashi, N; Yamazaki, T; Agematsu, K; Matsuzaki, S; Nakata, S; Baba, A
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 139(1), 1-8, 2006 - Successful treatment with methotrexate of a child with atlantoaxial subluxation from enthesitis-related arthritis
Kobayashi, N; Yasui, K; Nagumo, H; Agematsu, K; Koike, K
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 24(2), 211-212, 2006 - CD30+anaplastic large cell lymphoma complicated by pyoderma gangrenosum with increased levels of serum cytokines
Saito, S; Yasui, K; Hosoda, W; Ogawa, M; Kobayashi, N; Sakashita, K; Koike, K
EUROPEAN JOURNAL OF HAEMATOLOGY, 77(3), 251-254, 2006 - Polarization of Th1/Th2 in human CD4+ T cells separated by CD62L: analysis by transcription factors
Matsuzaki S, Shinozaki K, Kobayashi N, Agematsu K
ALLERGY, 60, 780-787, 2005 - Superoxide dismutase (SOD) as a potential inhibitory mediator ofinflammation via neutrophil apoptosis
Yasui K, Kobayashi N, Yamazaki T, Agematsu K, Matsuzaki S, Ito S, Nakata S, Baba A, Koike K
Free Radic Res, 39, 755-762, 2005 - Neutrophilic inflammation in childhood bronchial asthma
Yasui K, Kobayashi N, Yamazaki T, Koike K, Fukushima K, Taniuchi S, Kobayashi Y
Thorax, 60, 704-705, 2005 - Neutrophil-mediated inflammation in respiratory syncytial viral bronchiolitis
Yasui K, Baba A, Iwasaki Y, Kubo T, Aoyama K, Mori T, Yamazaki T, Kobayashi N, Ishiguro A
Pediatr Int, 47, 190-195, 2005 - Effective combination therapy using interferon-gamma and interleukin-2 for disseminated Mycobacterium avium complexinfection in a pediatric patient with AIDS
Sekiguchi Y, Yasui K, Yamazaki T, Agematsu K, Kobayashi N, Koike K
Clin Infect Dis, 41, e104-e106, 2005 - Thalidomide as an immunotherapeutic agent: The effects on neutrophil-mediated inflammation
Yasui, K; Kobayashi, N; Yamazaki, T; Agematsu, K
Current Pharmaceutical Design, 11(3), 395-401, 2005 - Bilineage acute leukemia of T-lymphoid and myeloid lineages
Kobayashi N, Matsuda K, Sakashita K, Matsuzaki S, Iwasaki R, Koike K
Haematologica, 89, 1139-1141, 2004 - Expansion of clonotype-restricted HLA-identical maternal CD4+ T cells in a patient with severe combined immunodeficiency and a homozygous mutation in the Artemis gene
Kobayashi N, Agematsu K, Nagumo H, Yasui K, Katsuyama Y, Yoshizawa K, Ota M, Yachie A, Komiyama A
Clin Immunol, 108, 159-166, 2003 - Novel Artemis gene mutations of radiosensitive severe combined immunodeficiency in Japanese families
Kobayashi N, Agematsu K, Sugita K, Sako M, Nonoyama S, Yachie A, Kumaki S, Tsuchiya S, Ochs HD, Sugita K, Fukushima Y, Komiyama A
Hum Genet, 112, 348-352, 2003 - IL-10 enhances B-cell IgE synthesis by promoting differentiation into plasma cells, a process that is inhibited by CD27/CD70 interaction
Kobayashi N, Nagumo H, Agematsu K
Clin Exp Immunol, 129, 446-452, 2002 - Absence of memory B cells in patients with common variable immunodeficiency
Agematsu K, Futatani T, Hokibara N, Kobayashi H, Takamoto M, Tsukada S, Suzuki H, Koyasu S, Miyawaki T, Sugane K, Komiyama A, Ochs HD
Clin Immunol, 103, 34-42, 2002 - Interferon-gamma and interteukin-2 combination therapy for a AIDS girl with mycobacterium avium-intracellulare complex infection.
Sekiguchi, Y; Kobayashi, N; Nagumo, H; Agematsu, K; Komiyama, A
Clinical Immunology, 103(3), S78-S78, 2002 - The different process of class switching and somatic hypermutation; a novel analysis by CD27(-) naive B cells
Nagumo, H; Agematsu, K; Kobayashi, N; Shinozaki, K; Hokibara, S; Nagase, H; Takamoto, M; Yasui, K; Sugane, K; Komiyama, A
BLOOD, 99(2), 567-575, 2002
