SHIBA Yuji
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences
Professor
Researcher Information
Web site
Research activity information
Award
Paper
- Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell-Derived Cardiac Spheroids.
Hideki Kobayashi; Shugo Tohyama; Hajime Ichimura; Noburo Ohashi; Shuji Chino; Yusuke Soma; Hidenori Tani; Yuki Tanaka; Xiao Yang; Naoko Shiba; Shin Kadota; Kotaro Haga; Taijun Moriwaki; Yuika Morita-Umei; Tomohiko C Umei; Otoya Sekine; Yoshikazu Kishino; Hideaki Kanazawa; Hiroyuki Kawagishi; Mitsuhiko Yamada; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
Circulation, Apr. 2024
Lead
- Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 1.
Naoko Shiba; Xiao Yang; Mitsuto Sato; Shin Kadota; Yota Suzuki; Masahiro Agata; Kohei Nagamine; Masaki Izumi; Yusuke Honda; Tomoya Koganehira; Hideki Kobayashi; Hajime Ichimura; Shinichiro Chuma; Junichi Nakai; Shugo Tohyama; Keiichi Fukuda; Daigo Miyazaki; Akinori Nakamura; Yuji Shiba
Molecular therapy. Nucleic acids, 34, 102060-102060, Dec. 2023
Lead - Mature human induced pluripotent stem cell-derived cardiomyocytes promote angiogenesis through alpha-B crystallin.
Yuki Tanaka; Shin Kadota; Jian Zhao; Hideki Kobayashi; Satomi Okano; Masaki Izumi; Yusuke Honda; Hajime Ichimura; Naoko Shiba; Takeshi Uemura; Yuko Wada; Shinichiro Chuma; Tsutomu Nakada; Shugo Tohyama; Keiichi Fukuda; Mitsuhiko Yamada; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba
Stem cell research & therapy, 14(1), 240-240, Sep. 2023
Lead - Cardiac Regeneration Using Pluripotent Stem Cells and Controlling Immune Responses.
Hajime Ichimura; Shuji Chino; Yuji Shiba
Heart, lung & circulation, 32(7), 836-843, Jul. 2023
Lead - Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration.
Hideki Kobayashi; Shugo Tohyama; Hideaki Kanazawa; Hajime Ichimura; Shuji Chino; Yuki Tanaka; Yota Suzuki; Jian Zhao; Naoko Shiba; Shin Kadota; Kazumasa Narita; Takafumi Naito; Tatsuichiro Seto; Koichiro Kuwahara; Yuji Shiba; Keiichi Fukuda
Journal of molecular and cellular cardiology, 174, 77-87, Jan. 2023
Lead - Restoring Dystrophin Expression with Duchenne Muscular Dystrophy Exon 45 Skipping in Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Mitsuto Sato; Naoko Shiba; Daigo Miyazaki; Yuji Shiba; Akinori Nakamura
Methods in molecular biology (Clifton, N.J.), 2587, 141-151, 2023
Lead - Chemical Genetics Reveals a Role of Squalene Synthase in TGFβ Signaling and Cardiomyogenesis.
Yasushi Takemoto; Shin Kadota; Itsunari Minami; Shinya Otsuka; Satoshi Okuda; Masahiro Abo; Louvy Lynn Punzalan; Yan Shen; Yuji Shiba; Motonari Uesugi
Angewandte Chemie (International ed. in English), 60(40), 21824-21831, Sep. 2021
Lead - Transplantation of Pluripotent Stem Cell-Derived Cardiomyocytes into a Myocardial Infarction Model of Cynomolgus Monkey.
Hideki Kobayashi; Hajime Ichimura; Noburou Ohashi; Yuji Shiba
Methods in molecular biology (Clifton, N.J.), 2320, 295-302, 2021
Lead - Pluripotent Stem Cells for Cardiac Regeneration - Current Status, Challenges, and Future Perspectives.
Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 84(12), 2129-2135, Nov. 2020
Lead - Establishment of a heart-on-a-chip microdevice based on human iPS cells for the evaluation of human heart tissue function.
Mosha Abulaiti; Yaxiaer Yalikun; Kozue Murata; Asako Sato; Mustafa M Sami; Yuko Sasaki; Yasue Fujiwara; Kenji Minatoya; Yuji Shiba; Yo Tanaka; Hidetoshi Masumoto
Scientific reports, 10(1), 19201-19201, Nov. 2020
Lead - Heart regeneration using pluripotent stem cells.
Shin Kadota; Yuki Tanaka; Yuji Shiba
Journal of cardiology, 76(5), 459-463, Nov. 2020
Lead - β-Arrestin-Biased AT1 Agonist TRV027 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate.
Toshihide Kashihara; Hiroyuki Kawagishi; Tsutomu Nakada; Takuro Numaga-Tomita; Shin Kadota; Elena E Wolf; Cheng-Kun Du; Yuji Shiba; Sachio Morimoto; Mitsuhiko Yamada
JACC. Basic to translational science, 5(11), 1057-1069, Nov. 2020
Lead - beta-Arrestin Biased AT(1) Agonist TRVO27 Causes a Neonatal-Specific Sustained Positive Inotropic Effect Without Increasing Heart Rate
Kashihara, Toshihide; Kawagishi, Hiroyuki; Nakada, Tsutomu; Numaga-Tomita, Takuro; Kadota, Shin; Wolf, Elena E.; Du, Cheng-Kun; Shiba, Yuji; Morimoto, Sachio; Yamada, Mitsuhiko;
JACC-BASIC TO TRANSLATIONAL SCIENCE, 5(11), 1057-1069, Nov. 2020 - Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
Hajime Ichimura; Shin Kadota; Toshihide Kashihara; Mitsuhiko Yamada; Kuniaki Ito; Hideki Kobayashi; Yuki Tanaka; Naoko Shiba; Shinichiro Chuma; Shugo Tohyama; Tatsuichiro Seto; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
Scientific reports, 10(1), 11883-11883, Jul. 2020
Lead - Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring.
Junjun Li; Lu Zhang; Leqian Yu; Itsunari Minami; Shigeru Miyagawa; Marcel Hörning; Ji Dong; Jing Qiao; Xiang Qu; Ying Hua; Nanae Fujimoto; Yuji Shiba; Yang Zhao; Fuchou Tang; Yong Chen; Yoshiki Sawa; Chao Tang; Li Liu
Communications biology, 3(1), 122-122, Mar. 2020
Lead - Amelioration of intracellular Ca2+ regulation by exon-45 skipping in Duchenne muscular dystrophy-induced pluripotent stem cell-derived cardiomyocytes.
Mitsuto Sato; Naoko Shiba; Daigo Miyazaki; Yuji Shiba; Yusuke Echigoya; Toshifumi Yokota; Hotake Takizawa; Yoshitsugu Aoki; Shin'ichi Takeda; Akinori Nakamura
Biochemical and biophysical research communications, 520(1), 179-185, Nov. 2019
Lead - Pluripotent Stem Cell-Derived Cardiomyocyte Transplantation for Heart Disease Treatment.
Shin Kadota; Yuji Shiba
Current cardiology reports, 21(8), 73-73, Jun. 2019
Lead - Therapeutic Potential of Pluripotent Stem Cells for Cardiac Repair after Myocardial Infarction.
Satomi Okano; Yuji Shiba
Biological & pharmaceutical bulletin, 42(4), 524-530, 2019
Lead - Cardiac Sodium Channel Disease Modeling Using Patient-Derived Induced Pluripotent Stem Cells.
Shin Kadota; Naoko Shiba; Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 81(12), 1764-1765, Nov. 2017
Lead - Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium.
Junjun Li; Itsunari Minami; Motoko Shiozaki; Leqian Yu; Shin Yajima; Shigeru Miyagawa; Yuji Shiba; Nobuhiro Morone; Satsuki Fukushima; Momoko Yoshioka; Sisi Li; Jing Qiao; Xin Li; Lin Wang; Hidetoshi Kotera; Norio Nakatsuji; Yoshiki Sawa; Yong Chen; Li Liu
Stem cell reports, 9(5), 1546-1559, Nov. 2017
Lead - Impact of extracellular matrix on engraftment and maturation of pluripotent stem cell-derived cardiomyocytes in a rat myocardial infarct model.
Tatsuki Ogasawara; Satomi Okano; Hajime Ichimura; Shin Kadota; Yuki Tanaka; Itsunari Minami; Motonari Uesugi; Yuko Wada; Naoto Saito; Kenji Okada; Koichiro Kuwahara; Yuji Shiba
Scientific reports, 7(1), 8630-8630, Aug. 2017
Lead - 多能性幹細胞を用いた心筋再生治療
門田 真; 柴 祐司
信州医学雑誌, 65(3), 143-152, 10 Jun. 2017 - Recent Progress Using Pluripotent Stem Cells for Cardiac Regenerative Therapy.
Hajime Ichimura; Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 81(7), 929-935, Jun. 2017
Lead - A Synthetic Hybrid Molecule for the Selective Removal of Human Pluripotent Stem Cells from Cell Mixtures.
Di Mao; Shin Ando; Shin-Ichi Sato; Ying Qin; Nao Hirata; Yousuke Katsuda; Eihachiro Kawase; Ting-Fang Kuo; Itsunari Minami; Yuji Shiba; Kazumitsu Ueda; Norio Nakatsuji; Motonari Uesugi
Angewandte Chemie (International ed. in English), 56(7), 1765-1770, Feb. 2017
Lead - Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts.
Yuji Shiba; Toshihito Gomibuchi; Tatsuichiro Seto; Yuko Wada; Hajime Ichimura; Yuki Tanaka; Tatsuki Ogasawara; Kenji Okada; Naoko Shiba; Kengo Sakamoto; Daisuke Ido; Takashi Shiina; Masamichi Ohkura; Junichi Nakai; Narumi Uno; Yasuhiro Kazuki; Mitsuo Oshimura; Itsunari Minami; Uichi Ikeda
Nature, 538(7625), 388-391, Oct. 2016
Lead - [iPS cells as a source of cardiac regeneration].
Tatsuki Ogasawara; Yuji Shiba
Nihon rinsho. Japanese journal of clinical medicine, 74 Suppl 6, 287-92, Aug. 2016
Lead - Association between estimated glomerular filtration rate and peripheral arterial disease.
Saeko Yamasaki; Atsushi Izawa; Megumi Koshikawa; Tatsuya Saigusa; Soichiro Ebisawa; Takashi Miura; Yuji Shiba; Takeshi Tomita; Yusuke Miyashita; Jun Koyama; Uichi Ikeda
Journal of cardiology, 66(5), 430-4, Nov. 2015
Lead - Differential roles of MMP-9 in early and late stages of dystrophic muscles in a mouse model of Duchenne muscular dystrophy.
Naoko Shiba; Daigo Miyazaki; Takahiro Yoshizawa; Kazuhiro Fukushima; Yuji Shiba; Yuji Inaba; Michihiro Imamura; Shin'ichi Takeda; Kenichi Koike; Akinori Nakamura
Biochimica et biophysica acta, 1852(10 Pt A), 2170-82, Oct. 2015
Lead - [Therapeutic angiogenesis by adipose - derived regenerative cell transplantation for severe peripheral artery disease].
Kazuhiro Kimura; Yuji Shiba; Uichi Ikeda
Nihon rinsho. Japanese journal of clinical medicine, 73 Suppl 5, 529-33, Jun. 2015
Lead - Transplantation of adipose tissue-derived stem cells improves cardiac contractile function and electrical stability in a rat myocardial infarction model.
Milan Gautam; Daiki Fujita; Kazuhiro Kimura; Hinako Ichikawa; Atsushi Izawa; Masamichi Hirose; Toshihide Kashihara; Mitsuhiko Yamada; Masafumi Takahashi; Uichi Ikeda; Yuji Shiba
Journal of molecular and cellular cardiology, 81, 139-49, Apr. 2015
Lead - A young patient with atypical type-B Wolff-Parkinson-White syndrome accompanied by left ventricular dysfunction.
Takahiro Takeuchi; Takeshi Tomita; Hiroki Kasai; Daisuke Kashiwagi; Koji Yoshie; Tomonori Yaguchi; Yasutaka Oguchi; Ayako Kozuka; Milan Gautam; Hirohiko Motoki; Ayako Okada; Yuji Shiba; Kazunori Aizawa; Atsushi Izawa; Yusuke Miyashita; Jun Koyama; Minoru Hongo; Uichi Ikeda
Journal of arrhythmia, 31(1), 50-4, Feb. 2015
Lead - New strategy for the treatment of myocarditis by cell-sheet technology.
Yuji Shiba
Circulation journal : official journal of the Japanese Circulation Society, 79(1), 51-2, 2015
Lead - Low levels of high-density lipoprotein cholesterol predict the presence of coronary artery disease in patients with aortic aneurysms.
Tatsuya Saigusa; Atsushi Izawa; Takashi Miura; Soichiro Ebisawa; Yuji Shiba; Yusuke Miyashita; Takeshi Tomita; Jun Koyama; Daisuke Fukui; Tamaki Takano; Jun Amano; Uichi Ikeda
Angiology, 65(8), 710-5, Sep. 2014
Lead - Electrical Integration of Human Embryonic Stem Cell-Derived Cardiomyocytes in a Guinea Pig Chronic Infarct Model.
Yuji Shiba; Dominic Filice; Sarah Fernandes; Elina Minami; Sarah K Dupras; Benjamin Van Biber; Peter Trinh; Yusuke Hirota; Joseph D Gold; Mohan Viswanathan; Michael A Laflamme
Journal of cardiovascular pharmacology and therapeutics, 19(4), 368-381, Jul. 2014
Lead - Importance of fatty acid compositions in patients with peripheral arterial disease.
Milan Gautam; Atsushi Izawa; Yuji Shiba; Hirohiko Motoki; Takahiro Takeuchi; Ayako Okada; Takeshi Tomita; Yusuke Miyashita; Jun Koyama; Uichi Ikeda
PloS one, 9(9), e107003, 2014
Lead - Presence of diastolic dysfunction in patients with peripheral artery disease.
Saeko Yamasaki; Atsushi Izawa; Yuji Shiba; Takeshi Tomita; Yusuke Miyashita; Jun Koyama; Uichi Ikeda
Angiology, 64(7), 540-3, Oct. 2013
Lead - Prostacyclin: a potential new target for endothelial progenitor cell-mediated angiogenesis.
Yuji Shiba; Uichi Ikeda
Circulation journal : official journal of the Japanese Circulation Society, 77(4), 906-7, 2013
Lead - Crucial role of hyaluronan in neointimal formation after vascular injury.
Yuichiro Kashima; Masafumi Takahashi; Yuji Shiba; Naoki Itano; Atsushi Izawa; Jun Koyama; Jun Nakayama; Shun'ichiro Taniguchi; Koji Kimata; Uichi Ikeda
PloS one, 8(3), e58760, 2013
Lead - Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts.
Yuji Shiba; Sarah Fernandes; Wei-Zhong Zhu; Dominic Filice; Veronica Muskheli; Jonathan Kim; Nathan J Palpant; Jay Gantz; Kara White Moyes; Hans Reinecke; Benjamin Van Biber; Todd Dardas; John L Mignone; Atsushi Izawa; Ramy Hanna; Mohan Viswanathan; Joseph D Gold; Michael I Kotlikoff; Narine Sarvazyan; Matthew W Kay; Charles E Murry; Michael A Laflamme
Nature, 489(7415), 322-5, Sep. 2012
Lead - Creation of human cardiac cell sheets using pluripotent stem cells.
Katsuhisa Matsuura; Masanori Wada; Tatsuya Shimizu; Yuji Haraguchi; Fumiko Sato; Kasumi Sugiyama; Kanako Konishi; Yuji Shiba; Hinako Ichikawa; Aki Tachibana; Uichi Ikeda; Masayuki Yamato; Nobuhisa Hagiwara; Teruo Okano
Biochemical and biophysical research communications, 425(2), 321-7, Aug. 2012
Lead - Targeting N-acetylglucosamine-bearing polymer-coated liposomes to vascular smooth muscle cells.
Mamiko Ise; Hirohiko Ise; Yuji Shiba; Satoshi Kobayashi; Mitsuaki Goto; Masafumi Takahashi; Toshihiro Akaike; Uichi Ikeda
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 14(4), 301-9, Dec. 2011
Lead - Notch signaling regulates the differentiation of bone marrow-derived cells into smooth muscle-like cells during arterial lesion formation.
Hiroshi Doi; Tatsuya Iso; Yuji Shiba; Hiroko Sato; Miki Yamazaki; Yoshiaki Oyama; Hideo Akiyama; Toru Tanaka; Tomoyuki Tomita; Masashi Arai; Masafumi Takahashi; Uichi Ikeda; Masahiko Kurabayashi
Biochemical and biophysical research communications, 381(4), 654-9, Apr. 2009
Lead - Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis.
Yuji Shiba; Masafumi Takahashi; Takeki Hata; Hideki Murayama; Hajime Morimoto; Hirohiko Ise; Takashi Nagasawa; Uichi Ikeda
Cardiovascular research, 81(1), 169-77, Jan. 2009
Lead - Cardiac applications for human pluripotent stem cells.
Yuji Shiba; Kip D Hauch; Michael A Laflamme
Current pharmaceutical design, 15(24), 2791-806, 2009
Lead - Deficiency of tumour necrosis factor-alpha and interferon-gamma in bone marrow cells synergistically inhibits neointimal formation following vascular injury.
Hideki Murayama; Masafumi Takahashi; Masaya Takamoto; Yuji Shiba; Hirohiko Ise; Jun Koyama; Yoh-Ichi Tagawa; Yoichiro Iwakura; Uichi Ikeda
Cardiovascular research, 80(2), 175-80, Nov. 2008
Lead - Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice.
Noriyuki Yajima; Masafumi Takahashi; Hajime Morimoto; Yuji Shiba; Yasuko Takahashi; Junya Masumoto; Hirohiko Ise; Junji Sagara; Jun Nakayama; Shun'ichiro Taniguchi; Uichi Ikeda
Circulation, 117(24), 3079-87, Jun. 2008
Lead - Critical role of bone marrow-derived ASC, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice.
Yajima N, Takahashi M, Morimoto H, Shiba Y, Takahashi Y, Masumoto J, Ise H, J Sagara, Nakayama J, Taniguchi S, Ikeda U.
Circulation, 117, 3079-3087, 2008
Lead - Models for the study of angiogenesis.
Yuji Shiba; Masafumi Takahashi; Uichi Ikeda
Current pharmaceutical design, 14(4), 371-7, 2008
Lead - Bone marrow-derived CXCR4+ cells mobilized by macrophage colony-stimulating factor participate in the reduction of infarct area and improvement of cardiac remodeling after myocardial infarction in mice.
Hajime Morimoto; Masafumi Takahashi; Yuji Shiba; Atsushi Izawa; Hirohiko Ise; Minoru Hongo; Kiyohiko Hatake; Kazuo Motoyoshi; Uichi Ikeda
The American journal of pathology, 171(3), 755-66, Sep. 2007
Lead - M-CSF accelerates neointimal formation in the early phase after vascular injury in mice: the critical role of the SDF-1-CXCR4 system.
Yuji Shiba; Masafumi Takahashi; Toru Yoshioka; Noriyuki Yajima; Hajime Morimoto; Atsushi Izawa; Hirohiko Ise; Kiyohiko Hatake; Kazuo Motoyoshi; Uichi Ikeda
Arteriosclerosis, thrombosis, and vascular biology, 27(2), 283-9, Feb. 2007
Lead - Granulocyte colony-stimulating factor (G-CSF) accelerates reendothelialization and reduces neointimal formation after vascular injury in mice.
Toru Yoshioka; Masafumi Takahashi; Yuji Shiba; Chihiro Suzuki; Hajime Morimoto; Atsushi Izawa; Hirohiko Ise; Uichi Ikeda
Cardiovascular research, 70(1), 61-9, Apr. 2006
Lead - [Post-myocardial infarction ventricular aneurysm and intractable ventricular tachycardia supported by left ventricular assist device: a case report].
Katsuhito Ueno; Toshio Konishi; Mutsumu Fukata; Kazuhiro Okura; Hiroshi Furukawa; Yuji Shiba; Kazuhiko Yumoto; Toshiyuki Tamaki; Akihiko Nogami; Ken-ichi Kato
Journal of cardiology, 43(5), 231-5, May 2004
Lead - Percutaneous cardiopulmonary support aids resuscitation from sustained ventricular tachycardia.
Atsushi Izawa; Osamu Kinoshita; Yuji Shiba; Wataru Takahashi; Shin-Ichiro Uchikawa; Hiroshi Imamura; Mafumi Owa; Keishi Kubo
Circulation journal : official journal of the Japanese Circulation Society, 67(12), 1061-3, Dec. 2003
Lead
Books and other publications
- 循環器ジャーナル 68 3
門田 真; 柴 祐司, バイオペースメーカー
医学書院, 422-427 2020心不全に対する再生医療の現状 eLetter 2019年 夏号
柴 祐司
日本心不全学会, 4-5 2019日本臨牀 75 増刊号4号
柴 祐司; 池田宇一, 皮下脂肪由来間葉系前句細胞
日本臨牀社, 256-260 2017化学工業 68 5
岡野怜己; 柴 祐司, 多能性幹細胞を用いた心筋再生治療の開発
小峰工業出版, 8/12 2017日本臨牀増刊号 74 6
小笠原達樹、柴 祐司, 最新冠動脈疾患学（下）
日本臨牀社, 287-292 20 Aug. 2016幹細胞を用いた心筋再生 14 2
柴 祐司, Single work, 循環器疾患における再生医療の展望
循環plus, 10-12 2013心筋細胞移植と不整脈 3 9
柴 祐司, Single work, 特集循環器再生医療の現状と展望
月刊循環器, 77-84 2013Research Themes
- 心筋再生を実用化するための免疫制御法の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
01 Apr. 2024 - 31 Mar. 2028 - 移植免疫の理解に基づく新たな心筋再生治療の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
01 Apr. 2024 - 31 Mar. 2025 - 自己細胞を用いた心臓再生への挑戦
科学研究費助成事業, 日本学術振興会, 挑戦的研究(萌芽)
信州大学
30 Jun. 2022 - 31 Mar. 2024 - 移植免疫の理解に基づく新たな心筋再生治療の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
信州大学
01 Apr. 2021 - 31 Mar. 2025 - 新しい心筋補填材料の開発～iPS細胞由来心筋細胞を用いたバイオシートの検討
科学研究費助成事業, 日本学術振興会, 基盤研究(C)
信州大学
01 Apr. 2021 - 31 Mar. 2024 - Development of a new myocardial regeneration therapy using human iPS-derived cardiomyocytes for severe heart failure
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Keio University
01 Apr. 2020 - 31 Mar. 2023 - Evaluation of Post-Transplant Arrhythmia in Human iPSC-Derived Purified Ventricular Cardiomyocytes
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Research (Exploratory)
Keio University
28 Jun. 2019 - 31 Mar. 2021 - Exploration of Self-Assembling Bioactive Small Molecules
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A)
Kyoto University
01 Apr. 2019 - 31 Mar. 2022 - iPS cells for cardiac electrical regeneration
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Research (Exploratory)
Shinshu University
29 Jun. 2018 - 31 Mar. 2020 - Development of DMD exon 3-9 skipping therapy using iPSc
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2018 - 31 Mar. 2021 - Development of a method of functional integration between host and graft on the transplantation therapy of human iPS cell-derived cardiac tissues
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Kyoto University
01 Apr. 2018 - 31 Mar. 2021 - Research on pathogenesis and development of therapies for cardiac failure using dystrophin-deficient-cardiomyocytes derived from DMD patients
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Shinshu University
01 Apr. 2018 - 31 Mar. 2021 - Transplantation study of iPS cell-derived cardiomyocytes in non-human primates
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2017 - 31 Mar. 2021 - 安全・配向・成熟心筋移植片の開発
科学研究費助成事業, 日本学術振興会, 基盤研究(B)
京都大学
01 Apr. 2015 - 31 Mar. 2018 - Exon 45 skipping theraphy using iPS cells deleted exons 46-55 in the DMD gene
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2015 - 31 Mar. 2018 - MHC-matched allogeneic transplantation of iPS cell-derived cardiomyocytes
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
Shinshu University
01 Apr. 2014 - 31 Mar. 2017 - Therapeutic angiogenesis using adipose-derived regenerative cell
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Shinshu University
01 Apr. 2014 - 31 Mar. 2017 - Multifaceted profiling of pluripotent stem cells applied in regenerative medicine
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (A)
Shinshu University
01 Apr. 2012 - 31 Mar. 2015 - Novel 3D-culture System for iPS Cell-Derived Cardiomyocytes for Cardiac Repair
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B)
Shinshu University
01 Apr. 2012 - 31 Mar. 2014
