SAITO Shoji
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
Shinshu University Hospital Clinical Division of Pediatrics
Senior Assistant Professor
Researcher Information
Research Keyword
- Pediatrics, Hematology, Cancer immunotherapy
Field Of Study
Career
- 2019 - Present
Shinshu University School of Medicine, Assistant Professor - 2018 - 2019
Shinshu University School of Medicine, Assistant Professor - 2014 - 2016
Baylor Colloge of Medicine, Postdoctral associates - 2013 - 2014
Shinshu University Hospital, Advance Center for Cellular Therapy, Assistant professor
Research activity information
Paper
- Associations between maternal per- and polyfluoroalkyl substances exposure and lipid levels in maternal and cord blood: The Japan environment and Children's study.
Kohei Hasegawa; Yuji Inaba; Shoji Saito; Takumi Shibazaki; Shoji F Nakayama; Michihiro Kamijima; Teruomi Tsukahara; Tetsuo Nomiyama
Environmental research, 263(Pt 3), 120217-120217, Dec. 2024
Lead - Successful ibrutinib treatment for pulmonary involvement in a post-transplant patient with inherited bone marrow failure syndrome and very short telomeres.
Yu Furui; Shoji Saito; Yuta Maruyama; Eri Okura; Koichi Hirabayashi; Miyuki Tanaka; Yozo Nakazawa
Pediatric blood & cancer, 71(12), e31314, Dec. 2024
Corresponding - Real-world outcomes of commercial tisagenlecleucel for children, adolescents, and young adults with acute lymphoblastic leukemia in Japan.
Itaru Kato; Daisuke Tomizawa; Motohiro Kato; Shinsuke Hirabayashi; Atsushi Manabe; Masahiro Irie; Yoji Sasahara; Yuki Arakawa; Katsuyoshi Koh; Hirotoshi Sakaguchi; Masanaka Sugiyama; Chitose Ogawa; Takahiro Kamiya; Shoji Saito; Yozo Nakazawa; Nobuhiro Nishio; Yoshiyuki Takahashi; Naoko Iwai; Souichi Adachi; Junko Takita; Takako Miyamura; Satomi Yokoyama; Utako Oba; Tamaki Ueda; Yuhki Koga; Hidefumi Hiramatsu
Transplantation and cellular therapy, Nov. 2024
Lead - Paediatric acute lymphoblastic leukaemia-associated haemophagocytic lymphohistiocytosis develops during prednisolone prephase.
Sota Tanabe; Yu Furui; Shoji Saito; Eri Okura; Yuichiro Ide; Yuka Takezawa; Yuta Maruyama; Kenichi Sakamoto; Koichi Hirabayashi; Miyuki Tanaka; Ryu Yanagisawa; Yozo Nakazawa
British journal of haematology, 205(5), 2031-2035, Nov. 2024, Refereed, Not invited
Corresponding - Azacitidine treatment for myeloid leukemia associated with Down syndrome: A nationwide retrospective study in Japan.
Shota Kato; Kentaro Nakashima; Genki Yamato; Shoji Saito; Yuichi Taneyama; Nobuyuki Yamamoto; Takako Miyamura; Keisuke Kato; Yuya Sato; Ai Yamada; Takahiro Kamiya; Takuro Nishikawa; Suguru Uemura; Daisuke Tomizawa; Hiroshi Moritake; Kiminori Terui; Takashi Taga; Daisuke Hasegawa
Pediatric blood & cancer, 71(10), e31244, Oct. 2024
Lead - Successful haploidentical bone marrow transplantation in Griscelli syndrome type 2 with non-busulfan-based regimen and post-transplantation cyclophosphamide: a case report and review of the literature.
Saori Yamada; Yuta Maruyama; Shoji Saito; Kazutoshi Komori; Hirokazu Morokawa; Eri Okura; Koichi Hirabayashi; Yu Furui; Takashi Kurata; Makoto Nishioka; Tetsuhiro Fukuyama; Kazuo Sakashita; Yozo Nakazawa
Pediatric hematology and oncology, 1-5, Oct. 2023, Refereed
Corresponding - Nelarabine, intensive L-asparaginase, and protracted intrathecal therapy for newly diagnosed T-cell acute lymphoblastic leukaemia in children and young adults (ALL-T11): a nationwide, multicenter, phase 2 trial including randomisation in the very high-risk group
Sato A, Hatta Y, Imai C, Oshima K, Okamoto Y, Deguchi T, Hashii Y, Fukushima T, Hori T, Kiyokawa N, Kato M, Saito S, Anami K, Sakamoto T, Kosaka Y, Suenobu S, Imamura T, Kada A, Saito AM, Manabe A, Kiyoi H, Matsumura I, Koh K, Watanabe A, Miyazaki Y, Horibe K.
Lancet Haematol, 10(6), e419-e432, Jun. 2023 - Factors Affecting Day-to-Day Variations in Tacrolimus Concentration among Children and Young Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.
Yuta Maruyama; Yuya Maejima; Koichi Hirabayashi; Hirokazu Morokawa; Eri Okura; Shoji Saito; Yozo Nakazawa
Transplantation and cellular therapy, 29(4), 270.e1-270.e8, Apr. 2023
Lead - 急性骨髄性白血病に対する非ウイルス遺伝子改変IGF1R CAR-T細胞の開発
村上 陽太; 大野 龍之助; 丸山 悠太; 平林 耕一; 齋藤 章治; 田中 美幸; 柳生 茂希; 中沢 洋三
日本小児科学会雑誌, 127(2), 295-295, Feb. 2023
Lead - Basophil activation test for allergic and febrile non-haemolytic transfusion reactions among paediatric patients with haematological or oncological disease
Usami Y, Yanagisawa R, Kanai R, Ide Y, Konno S, Iwama M, Futatsugi A, Takeshita T, Furui Y, Komori K, Kurata T, Saito S, Tanaka M, Nakazawa Y, Sakashita K, Tozuka M.
Vox Sang, 118(1), 41-48, Jan. 2023 - Non-viral inducible caspase 9 mRNA delivery using lipid nanoparticles against breast cancer: An in vitro study.
Ikumi Nakashima; Shoji Saito; Eiichi Akahoshi; Shigeki Yagyu; Mitsuko Sugano-Ishihara; Yozo Nakazawa
Biochemical and biophysical research communications, 635, 144-153, Dec. 2022, Refereed
Corresponding - Basophil activation test for allergic and febrile non-haemolytic transfusion reactions among paediatric patients with haematological or oncological disease.
Yoko Usami; Ryu Yanagisawa; Ryo Kanai; Yuichiro Ide; Saori Konno; Maria Iwama; Akiko Futatsugi; Tomoko Takeshita; Yu Furui; Kazutoshi Komori; Takashi Kurata; Shoji Saito; Miyuki Tanaka; Yozo Nakazawa; Kazuo Sakashita; Minoru Tozuka
Vox sanguinis, Oct. 2022
Lead - Comment on: Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients.
Daisuke Matsuoka; Koichi Hirabayashi; Tsubasa Murase; Shoji Saito; Yozo Nakazawa
Pediatric blood & cancer, 69(9), e29634, Sep. 2022
Lead - Prognostic factors of children and adolescents with T-cell acute lymphoblastic leukemia after allogeneic transplantation.
Hisashi Ishida; Motohiro Kato; Yuta Kawahara; Sae Ishimaru; Yuho Najima; Shinichi Kako; Maho Sato; Mitsuteru Hiwatari; Maiko Noguchi; Keisuke Kato; Katsuyoshi Koh; Keiko Okada; Fuminori Iwasaki; Ryoji Kobayashi; Shunji Igarashi; Shoji Saito; Yoshiyuki Takahashi; Atsushi Sato; Junji Tanaka; Yoshiko Hashii; Yoshiko Atsuta; Hirotoshi Sakaguchi; Toshihiko Imamura
Hematological oncology, 40(3), 457-468, Aug. 2022
Lead - Skin and soft tissue infections in adolescent chronic myeloid leukemia under dasatinib treatment.
Eriko Uchida; Shoji Saito; Daisuke Morita; Eri Okura; Koichi Hirabayashi; Miyuki Tanaka; Hideyuki Nakazawa; Akane Minagawa; Yozo Nakazawa
Pediatric blood & cancer, 69(8), e29714, Aug. 2022, Refereed
Corresponding - Impact of KIR-ligand mismatch on pediatric T-cell acute lymphoblastic leukemia in unrelated cord blood transplantation.
Yuta Kawahara; Sae Ishimaru; Junji Tanaka; Shinichi Kako; Masahiro Hirayama; Minoru Kanaya; Hisashi Ishida; Maho Sato; Ryoji Kobayashi; Motohiro Kato; Kumiko Goi; Shoji Saito; Yuhki Koga; Yoshiko Hashii; Koji Kato; Atsushi Sato; Yoshiko Atsuta; Hirotoshi Sakaguchi
Transplantation and cellular therapy, 28(9), 598.e1-598.e8, Jun. 2022
Lead - Relationship between allergic transfusion reactions and allergic predisposition among pediatric patients with hematological/oncological disease.
Ryu Yanagisawa; Nau Ishimine; Kazutoshi Komori; Takashi Kurata; Shoji Saito; Miyuki Tanaka; Kazuo Sakashita; Minoru Tozuka; Yozo Nakazawa
Transfusion, 62(5), 1035-1044, May 2022
Lead - Outcomes of third allogeneic hematopoietic stem cell transplantation in relapsed/refractory acute leukemia after a second transplantation.
Shinichi Kobayashi; Yoshinobu Kanda; Takaaki Konuma; Yoshihiro Inamoto; Kimikazu Matsumoto; Naoyuki Uchida; Kazuhiro Ikegame; Toshihiro Miyamoto; Noriko Doki; Hirohisa Nakamae; Yuta Katayama; Satoshi Takahashi; Souichi Shiratori; Shoji Saito; Toshiro Kawakita; Junya Kanda; Takahiro Fukuda; Yoshiko Atsuta; Fumihiko Kimura
Bone marrow transplantation, 57(1), 43-50, Jan. 2022
Lead - Hematopoietic Cell Transplantation Rescues Inflammatory Bowel Disease and Dysbiosis of Gut Microbiota in XIAP Deficiency.
Shintaro Ono; Kozue Takeshita; Yuko Kiridoshi; Motohiro Kato; Takahiro Kamiya; Akihiro Hoshino; Masakatsu Yanagimachi; Katsuhiro Arai; Ichiro Takeuchi; Nariaki Toita; Toshihiko Imamura; Yoji Sasahara; Junichi Sugita; Kazuko Hamamoto; Masanobu Takeuchi; Shoji Saito; Masaei Onuma; Hiroshi Tsujimoto; Masahiro Yasui; Takashi Taga; Yuki Arakawa; Yuichi Mitani; Nobuyuki Yamamoto; Kohsuke Imai; Wataru Suda; Masahira Hattori; Osamu Ohara; Tomohiro Morio; Kenya Honda; Hirokazu Kanegane
The journal of allergy and clinical immunology. In practice, 9(10), 3767-3780, Jul. 2021
Lead - Mutated GM-CSF-based CAR-T cells targeting CD116/CD131 complexes exhibit enhanced anti-tumor effects against acute myeloid leukaemia.
Aiko Hasegawa; Shoji Saito; Shogo Narimatsu; Shigeru Nakano; Mika Nagai; Hideki Ohnota; Yoichi Inada; Hirokazu Morokawa; Ikumi Nakashima; Daisuke Morita; Yuichiro Ide; Kazuyuki Matsuda; Haruko Tashiro; Shigeki Yagyu; Miyuki Tanaka; Yozo Nakazawa
Clinical & translational immunology, 10(5), e1282, 2021, Refereed
Corresponding - A lymphodepleted non-human primate model for the assessment of acute on-target and off-tumor toxicity of human chimeric antigen receptor-T cells.
Shigeki Yagyu; Hidemi Mochizuki; Kumiko Yamashima; Hiroshi Kubo; Shoji Saito; Miyuki Tanaka; Kengo Sakamoto; Akihito Shimoi; Yozo Nakazawa
Clinical & translational immunology, 10(6), e1291, 2021
Lead - Assessment of kidney function using inulin-based and estimated glomerular filtration rates before and after allogeneic hematopoietic stem cell transplantation in pediatric patients.
Daisuke Matsuoka; Koichi Hirabayashi; Tsubasa Murase; Shoji Saito; Yoshihiko Hidaka; Yozo Nakazawa
Pediatric blood & cancer, 67(12), e28733, Dec. 2020
Lead - 小児・AYA腫瘍の最近の進歩 小児AYAがんに対する腫瘍指向性リポソームを用いた新規mRNA医薬の開発
齋藤 章治; 赤星 英一; 菅野 美津子; 柳生 茂希; 中沢 洋三
日本癌学会総会記事, 79回, SST6-7, Oct. 2020
Lead - piggyBac遺伝子改変CAR-T細胞の安全性評価のための霊長類モデルの開発
師川 紘一; 田中 美幸; 柳生 茂希; 望月 秀美; 下井 昭仁; 齋藤 章治; 中沢 洋三
日本がん免疫学会総会プログラム・抄録集, 24回, 117-117, Sep. 2020
Lead - Transfusion outcome for volume- and plasma-reduced platelet concentrates for pediatric patients.
Miyuki Tanaka; Ryu Yanagisawa; Manjiro Yamanaka; Saori Konno; Kayo Takemura; Shunsuke Kojima; Eri Okura; Daisuke Morita; Shoji Saito; Kazutoshi Komori; Haruka Matsuzawa; Kazuo Sakashita; Minoru Tozuka; Yozo Nakazawa
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 59(4), 102776-102776, Aug. 2020
Lead - 遺伝子改変T細胞の実用化のための霊長類モデルを用いた安全性評価系の開発
望月 秀美; 坂本 憲吾; 師川 紘一; 田中 美幸; 齋藤 章治; 柳生 茂希; 中沢 洋三; 下井 昭仁
The Journal of Toxicological Sciences, 45(Suppl.), S85-S85, Jun. 2020
Lead - Comparative analysis of graft-versus-host disease prophylaxis with tacrolimus in combination with methylprednisolone or methotrexate after umbilical cord blood transplantation.
Tomonari Shigemura; Kazuo Sakashita; Eri Okura; Daisuke Morita; Kazutoshi Komori; Takashi Kurata; Koichi Hirabayashi; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Yozo Nakazawa
International journal of hematology, 111(5), 702-710, May 2020
Lead - Complete measurable residual disease response after combination chemotherapy with AML-type and ALL-type regimens in pediatric B/myeloid acute bilineal leukemia.
Shoji Saito; Chiaki Taira; Kazuyuki Matsuda; Ryu Yanagisawa; Daisuke Morita; Tomonari Shigemura; Kentaro Yoshikawa; Miyuki Tanaka; Kazuo Sakashita; Saki Mukai; Shigetaka Shimodaira; Kenichi Koike; Yozo Nakazawa
Leukemia & lymphoma, 61(4), 967-970, Apr. 2020
Lead, Corresponding - Delayed methotrexate clearance and acute kidney injury after high-dose methotrexate chemotherapy concurrent with dasatinib in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia: A case report.
Haruka Morota; Shoji Saito; Eriko Uchida; Eri Okura; Daisuke Matsuoka; Yoshihiko Hidaka; Takenori Natsume; Tatsuo Watanabe; Tomonari Shigemura; Daisuke Morita; Miyuki Tanaka; Takashi Kurata; Kazuo Sakashita; Yozo Nakazawa
Pediatric blood & cancer, 67(4), e28173, Apr. 2020, Refereed
Corresponding - Multiple heterogeneous bone invasions of B lymphoblastic lymphoma with the TCF3/PBX1 fusion gene: a case report.
Eri Okura; Shoji Saito; Takenori Natsume; Daisuke Morita; Miyuki Tanaka; Nobutaka Kiyokawa; Yozo Nakazawa
International journal of hematology, 111(2), 163-165, Feb. 2020, Refereed
Corresponding - Prophylactic piperacillin administration in pediatric patients with solid tumors following different intensities of chemotherapy.
Shoji Saito; Ryu Yanagisawa; Kisei Minami; Eriko Uchida; Tatsuo Watanabe; Kazutoshi Komori; Takashi Kurata; Tomohiko Nakamura; Kazuo Sakashita
Pediatrics international : official journal of the Japan Pediatric Society, 62(2), 158-168, Feb. 2020, Refereed
Lead - Autologous non-human primate model for safety assessment of piggyBac transposon-mediated chimeric antigen receptor T cells on granulocyte-macrophage colony-stimulating factor receptor.
Hirokazu Morokawa; Shigeki Yagyu; Aiko Hasegawa; Miyuki Tanaka; Shoji Saito; Hidemi Mochizuki; Kengo Sakamoto; Akihito Shimoi; Yozo Nakazawa
Clinical & translational immunology, 9(11), e1207, 2020
Lead - Ovarian function after allogeneic hematopoietic stem cell transplantation in children and young adults given 8-Gy total body irradiation-based reduced-toxicity myeloablative conditioning.
Kazutoshi Komori; Koichi Hirabayashi; Daisuke Morita; Yosuke Hara; Takashi Kurata; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Kazuo Sakashita; Kenichi Koike; Yozo Nakazawa
Pediatric transplantation, 23(3), e13372, May 2019
Lead - Proton Beam Therapy for Adolescent Primary Central Nervous System Lymphoma With Residual Tumor After Intensive Chemotherapy: A Case Report
Komori, Kazutoshi; Saito, Shoji; Araya, Masayuki; Morita, Daisuke; Kurata, Takashi; Hirabayashi, Koichi; Tanaka, Miyuki; Koiwai, Keiichiro; Tauchi, Katsunori; Masaki, Hidekazu; Nakazawa, Yozo;
PRACTICAL RADIATION ONCOLOGY, 9(5), 333-337, 2019, Refereed - Radiation necrosis following proton therapy successfully treated by low-dose bevacizumab in a patient with relapsed anaplastic ependymoma.
Shoji Saito; Yosuke Miyairi; Masayuki Araya; Shoji Yomo; Haruki Kuwabara; Eriko Uchida; Tatsuo Watanabe; Takashi Kurata; Kazuo Sakashita; Hiroaki Shigeta
Pediatric blood & cancer, 65(8), e27088, Aug. 2018, Refereed
Corresponding - Successful induction of therapeutic urinary concentration by intravenous ganciclovir and oral valganciclovir with remission of adenoviral hemorrhagic cystitis after cord blood transplantation.
Toshimitsu Yanagisawa; Shoji Saito; Yoshihiko Katsuyama; Koichi Hirabayashi; Tomonari Shigemura; Miyuki Tanaka; Kazuo Sakashita; Yozo Nakazawa
Pediatric transplantation, e13241, Jun. 2018, Refereed
Lead - Feasibility and Immune Response of WT1 Peptide Vaccination in Combination with OK-432 for Paediatric Solid Tumors.
Koichi Hirabayashi; Ryu Yanagisawa; Shoji Saito; Yumiko Higuchi; Terutsugu Koya; Kenji Sano; Shigeo Koido; Masato Okamoto; Haruo Sugiyama; Yozo Nakazawa; Shigetaka Shimodaira
Anticancer research, 38(4), 2227-2234, Apr. 2018
Lead - Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells.
Daisuke Morita; Nobuhiro Nishio; Shoji Saito; Miyuki Tanaka; Nozomu Kawashima; Yusuke Okuno; Satoshi Suzuki; Kazuyuki Matsuda; Yasuhiro Maeda; Matthew H Wilson; Gianpietro Dotti; Cliona M Rooney; Yoshiyuki Takahashi; Yozo Nakazawa
Molecular therapy. Methods & clinical development, 8, 131-140, Mar. 2018, Refereed
Corresponding - Increasing Risk of Disturbed Root Development in Permanent Teeth in Childhood Cancer Survivors Undergoing Cancer Treatment at Older Age.
Miyuki Tanaka; Takahiro Kamata; Ryu Yanagisawa; Daisuke Morita; Shoji Saito; Kazuo Sakashita; Masaaki Shiohara; Hiroshi Kurita; Kenichi Koike; Yozo Nakazawa
Journal of pediatric hematology/oncology, 39(3), e150-e154, Apr. 2017
Lead - Nonocclusive Mesenteric Ischemia after Chemotherapy in an Adolescent Patient with a History of Three Allogeneic Hematopoietic Stem Cell Transplantations for Acute Lymphoblastic Leukemia.
Koichi Hirabayashi; Mitsuho Takatsuki; Mitsuo Motobayashi; Takashi Kurata; Shoji Saito; Tomonari Shigemura; Yozo Nakazawa; Kazuo Sakashita; Satoshi Ishizone; Hiroyoshi Ota; Kenichi Koike
Pediatrics and neonatology, 58(1), 81-84, Feb. 2017
Lead - Catheter-Related Bacteremia Due to Gordonia sputi in a Patient with Acute Lymphocytic Leukemia: a Case Report.
Tatsuya Negishi; Takehisa Matsumoto; Shoji Saito; Eriko Kasuga; Kazuki Horiuchi; Tatsuya Natori; Kenta Takehara; Mitsutoshi Sugano; Takayuki Honda
Japanese journal of infectious diseases, 69(4), 342-3, Jul. 2016
Lead - Clinical and laboratory outcomes after umbilical cord blood transplantation in a patient with mucolipidosis II alpha/beta.
Takumi Shibazaki; Koichi Hirabayashi; Shoji Saito; Tomonari Shigemura; Yozo Nakazawa; Kazuo Sakashita; Mineo Takagi; Masaaki Shiohara; Kaori Adachi; Eiji Nanba; Norio Sakai; Kenichi Koike
American journal of medical genetics. Part A, 170A(5), 1278-82, May 2016
Lead - Loss of Mismatched HLA on the Leukemic Blasts of Patients With Relapsed Lymphoid Malignancies Following Bone Marrow Transplantation From Related Donors With HLA Class II Mismatches in the Graft Versus Host Direction.
Koichi Hirabayashi; Takashi Kurata; Kazuki Horiuchi; Shoji Saito; Tomonari Shigemura; Miyuki Tanaka; Ryu Yanagisawa; Kazuyuki Matsuda; Kazuo Sakashita; Kenichi Koike; Yozo Nakazawa
Pediatric blood & cancer, 63(4), 709-11, Apr. 2016
Lead - Intrathecal donor lymphocyte infusion for isolated leukemia relapse in the central nervous system following allogeneic stem cell transplantation: a case report and literature review.
Ryu Yanagisawa; Yozo Nakazawa; Kazuo Sakashita; Shoji Saito; Miyuki Tanaka; Masaaki Shiohara; Shigetaka Shimodaira; Kenichi Koike
International journal of hematology, 103(1), 107-11, Jan. 2016
Lead - GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies.
Xinan Wang; Hideki Muramatsu; Yusuke Okuno; Hirotoshi Sakaguchi; Kenichi Yoshida; Nozomu Kawashima; Yinyan Xu; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Shoji Saito; Yozo Nakazawa; Taro Masunari; Tadashi Hirose; Shaimaa Elmahdi; Atsushi Narita; Sayoko Doisaki; Olfat Ismael; Hideki Makishima; Asahito Hama; Satoru Miyano; Yoshiyuki Takahashi; Seishi Ogawa; Seiji Kojima
Haematologica, 100(10), e398-401, Oct. 2015
Lead - Safety and tolerability of allogeneic dendritic cell vaccination with induction of Wilms tumor 1-specific T cells in a pediatric donor and pediatric patient with relapsed leukemia: a case report and review of the literature.
Shoji Saito; Ryu Yanagisawa; Kentaro Yoshikawa; Yumiko Higuchi; Terutsugu Koya; Kiyoshi Yoshizawa; Miyuki Tanaka; Kazuo Sakashita; Takashi Kobayashi; Takashi Kurata; Koichi Hirabayashi; Yozo Nakazawa; Masaaki Shiohara; Yoshikazu Yonemitsu; Masato Okamoto; Haruo Sugiyama; Kenichi Koike; Shigetaka Shimodaira
Cytotherapy, 17(3), 330-5, Mar. 2015, Refereed
Lead - Successful treatment for West syndrome with severe combined immunodeficiency.
Mitsuo Motobayashi; Yuji Inaba; Tetsuhiro Fukuyama; Takashi Kurata; Taemi Niimi; Shoji Saito; Naoko Shiba; Takafumi Nishimura; Tomonari Shigemura; Yozo Nakazawa; Norimoto Kobayashi; Kazuo Sakashita; Kazunaga Agematsu; Motoki Ichikawa; Kenichi Koike
Brain & development, 37(1), 140-4, Jan. 2015
Lead - Evaluation of Mucorales DNA load in cerebrospinal fluid in a patient with possible cerebral mucormycosis treated with intravenous liposomal amphotericin B.
Tomonari Shigemura; Yozo Nakazawa; Kazuyuki Matsuda; Mitsuo Motobayashi; Shoji Saito; Kenichi Koike
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 29, 200-2, Dec. 2014
Lead - Reduced-toxicity myeloablative conditioning consisting of 8-Gy total body irradiation, cyclophosphamide and fludarabine for pediatric hematological malignancies.
Koichi Hirabayashi; Yozo Nakazawa; Kazuo Sakashita; Takashi Kurata; Shoji Saito; Kentaro Yoshikawa; Miyuki Tanaka; Ryu Yanagisawa; Kenichi Koike
Scientific reports, 4, 6942-6942, Nov. 2014
Lead - Anti-leukemic potency of piggyBac-mediated CD19-specific T cells against refractory Philadelphia chromosome-positive acute lymphoblastic leukemia.
Shoji Saito; Yozo Nakazawa; Akane Sueki; Kazuyuki Matsuda; Miyuki Tanaka; Ryu Yanagisawa; Yasuhiro Maeda; Yuko Sato; Seiichi Okabe; Takeshi Inukai; Kanji Sugita; Matthew H Wilson; Cliona M Rooney; Kenichi Koike
Cytotherapy, 16(9), 1257-69, Sep. 2014, Refereed
Lead - Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation.
Tomonari Shigemura; Yozo Nakazawa; Kazuyuki Matsuda; Kenji Sano; Takashi Yaguchi; Mitsuo Motobayashi; Shoji Saito; Shunsuke Noda; Norimoto Kobayashi; Kazunaga Agematsu; Takayuki Honda; Kenichi Koike
International journal of hematology, 100(2), 206-9, Aug. 2014
Lead - Myeloid progenitors with PTPN11 and nonRAS pathway gene mutations are refractory to treatment with 6-mercaptopurine in juvenile myelomonocytic leukemia
Matsuda, K; Nakazawa, Y; Iwashita, C; Kurata, T; Hirabayashi, K; Saito, S; Tanaka, M; Yoshikawa, K; Yanagisawa, R; Sakashita, K; Sasaki, S; Honda, T; Koike, K
Leukemia, 28(7), 1545-1548, Jul. 2014, Refereed - Risk factors for diabetes mellitus and impaired glucose tolerance following allogeneic hematopoietic stem cell transplantation in pediatric patients with hematological malignancies.
Kanae Hirabayashi; Yozo Nakazawa; Hiroki Matsuura; Yosuke Hara; Takashi Kurata; Koichi Hirabayashi; Shoji Saito; Kentaro Yoshikawa; Miyuki Tanaka; Ryu Yanagisawa; Kazuo Sakashita; Kenichi Koike
International journal of hematology, 99(4), 477-86, Apr. 2014
Lead - Successful cord blood transplantation after repeated transfusions of unmobilized neutrophils in addition to antifungal treatment in an infant with chronic granulomatous disease complicated by invasive pulmonary aspergillosis.
Tomonari Shigemura; Yozo Nakazawa; Kentaro Yoshikawa; Koichi Hirabayashi; Shoji Saito; Norimoto Kobayashi; Kazuo Sakashita; Masaaki Shiohara; Taizo Wada; Shigetaka Shimodaira; Kazunaga Agematsu; Kenichi Koike
Transfusion, 54(3), 516-21, Mar. 2014
Lead - Usefulness of allogeneic hematopoietic stem cell transplantation in first complete remission for pediatric blastic plasmacytoid dendritic cell neoplasm with skin involvement: a case report and review of literature.
Kazuo Sakashita; Shoji Saito; Ryu Yanagisawa; Miyuki Tanaka; Kentaro Yoshikawa; Koichi Hirabayashi; Keiko Tsukahara; Mitsuo Motobayashi; Yozo Nakazawa; Kenichi Koike
Pediatric blood & cancer, 60(11), E140-2, Nov. 2013
Lead - Replaced platelet concentrates containing a new additive solution, M-sol: safety and efficacy for pediatric patients.
Ryu Yanagisawa; Shigetaka Shimodaira; Shunsuke Kojima; Nobuhiko Nakasone; Shinsuke Ishikawa; Kayo Momose; Takayuki Honda; Kentaro Yoshikawa; Shoji Saito; Miyuki Tanaka; Yozo Nakazawa; Kazuo Sakashita; Masaaki Shiohara; Mitsuaki Akino; Junichi Hirayama; Hiroshi Azuma; Kenichi Koike
Transfusion, 53(9), 2053-60, Sep. 2013
Lead - Recipient seropositivity for adenovirus type 11 (AdV11) is a highly predictive factor for the development of AdV11-induced hemorrhagic cystitis after allogeneic hematopoietic SCT.
Nakazawa Y, Saito S, Yanagisawa R, Suzuki T, Ito T, Ishida F, Muramatsu H, Matsumoto K, Kato K, Ishida H, Umeda K, Adachi S, Nakahata T, Koike K.
Bone Marrow Transplant., 48(5), 737-9, May 2013, Refereed - Food allergy after cord blood transplantation in children.
Kazuo Sakashita; Yozo Nakazawa; Ryu Yanagisawa; Miyuki Tanaka; Shoji Saito; Kentaro Yoshikawa; Koichi Hirabayashi; Mai Kusakari; Sawako Kato; Nao Hidaka; Yoshiko Nakayama; Tomonari Shigemura; Norimoto Kobayashi; Mikiko Kobayashi; Masaaki Shiohara; Kenichi Koike
British journal of haematology, 158(5), 672-6, Sep. 2012
Lead - Critical illness polyneuropathy and myopathy caused by Bacillus cereus sepsis in acute lymphoblastic leukemia.
Koichi Hirabayashi; Masaaki Shiohara; Takefumi Suzuki; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Goro Tsuruta; Tetsuhiro Fukuyama; Yoshihiko Hidaka; Yozo Nakazawa; Takashi Shimizu; Kazuo Sakashita; Kenichi Koike
Journal of pediatric hematology/oncology, 34(3), e110-3, Apr. 2012
Lead - Application of allele-specific quantitative PCR using genomic DNA to monitor minimal residual disease based on mutant gene levels following allogeneic hematopoietic stem cell transplantation in patients with hematological malignancies: comparison of mutant levels with autologous DNA percentage by short tandem repeat-PCR.
Chiaki Taira; Kazuyuki Matsuda; Shoji Saito; Kazuo Sakashita; Mitsutoshi Sugano; Nobuo Okumura; Takayuki Honda
Clinica chimica acta; international journal of clinical chemistry, 413(3-4), 516-9, Feb. 2012
Lead - Genetic analysis of TP53 in childhood myelodysplastic syndrome and juvenile myelomonocytic leukemia.
Shoji Saito; Kazuyuki Matsuda; Chiaki Taira; Kenji Sano; Miyuki Tanaka-Yanagisawa; Ryu Yanagisawa; Yozo Nakazawa; Kazuo Sakashita; Masaaki Shiohara; Kenichi Koike
Leukemia research, 35(12), 1578-84, Dec. 2011, Refereed
Lead - Retrospective analysis of risk factors for development of liver dysfunction in transient leukemia of Down syndrome.
Koichi Hirabayashi; Masaaki Shiohara; Daijiro Takahashi; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Kazuo Sakashita; Tomohiko Nakamura; Eizaburo Ishii; Kenichi Koike
Leukemia & lymphoma, 52(8), 1523-7, Aug. 2011
Lead - Disappearance of minimal residual disease after the early withdrawal of immunosuppressants in a patient with juvenile myelomonocytic leukemia.
Ryu Yanagisawa; Kazuyuki Matsuda; Kazuo Sakashita; Yozo Nakazawa; Miyuki Tanaka; Shoji Saito; Kentaro Yoshikawa; Takehiko Kamijo; Masaaki Shiohara; Kenichi Koike
Pediatric blood & cancer, 56(3), 501-2, Mar. 2011
Lead - Increased pretransplant QT dispersion as a risk factor for the development of cardiac complications during and after preparative conditioning for pediatric allogeneic hematopoietic stem cell transplantation.
Noriko Motoki; Takashi Shimizu; Yohei Akazawa; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Hirohiko Motoki; Yozo Nakazawa; Kazuo Sakashita; Yasushi Iwasaki; Masaaki Shiohara; Kenichi Koike
Pediatric transplantation, 14(8), 986-92, Dec. 2010
Lead - Polymyxin-direct hemoperfusion for sepsis-induced multiple organ failure.
Koichi Hirabayashi; Masaaki Shiohara; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Goro Tsuruta; Tetsuhiro Fukuyama; Yoshihiko Hidaka; Yozo Nakazawa; Takashi Shimizu; Kazuo Sakashita; Kenichi Koike
Pediatric blood & cancer, 55(1), 202-5, Jul. 2010
Lead - Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations.
Kazuyuki Matsuda; Chiaki Taira; Kazuo Sakashita; Shoji Saito; Miyuki Tanaka-Yanagisawa; Ryu Yanagisawa; Yozo Nakazawa; Masaaki Shiohara; Keitaro Fukushima; Megumi Oda; Takayuki Honda; Tatsutoshi Nakahata; Kenichi Koike
Blood, 115(26), 5429-31, Jul. 2010
Lead - Ela2 mutations and clinical manifestations in familial congenital neutropenia.
Masaaki Shiohara; Tomonari Shigemura; Shoji Saito; Miyuki Tanaka; Ryu Yanagisawa; Kazuo Sakashita; Hiroshi Asada; Eizaburo Ishii; Kazutoshi Koike; Motoaki Chin; Masao Kobayashi; Kenichi Koike
Journal of pediatric hematology/oncology, 31(5), 319-24, May 2009
Lead - Bilateral perisylvian polymicrogyria, periventricular nodular heterotopia, and left ventricular noncompaction in a girl with 10.5-11.1 Mb terminal deletion of 1p36.
Shoji Saito; Rie Kawamura; Tomoki Kosho; Takashi Shimizu; Koki Aoyama; Kenichi Koike; Takahito Wada; Naomichi Matsumoto; Mitsuhiro Kato; Keiko Wakui; Yoshimitsu Fukushima
American journal of medical genetics. Part A, 146A(22), 2891-7, Nov. 2008, Refereed
Lead
MISC
- Comprehensive Genetic Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Leukemia Entity
Akira Nishimura; Kazuaki Yokoyama; Chika Yamagishi; Toshihiko Imamura; Takuya Naruto; Tomohiro Morio; Yukie Tanaka; Akinori Kanai; Hirotaka Matsui; Naoko Higuchi; Akiko Takada; Haruna Okuno; Shoji Saito; Shuhei Karakawa; Shogo Kobayashi; Daisuke Hasegawa; Hiroyuki Fujisaki; Daiichiro Hasegawa; Kazutoshi Koike; Takashi Koike; Shinya Rai; Katsutsugu Umeda; Hideki Sano; Yujin Sekinaka; Atsushi Ogawa; Akitoshi Kinoshita; Norio Shiba; Mizuka Miki; Fumihiko Kimura; Hideki Nakayama; Yozo Nakazawa; Takashi Taga; Tomohiko Taki; Souichi Adachi; Atsushi Manabe; Katsuyoshi Koh; Yasushi Ishida; Arinobu Tojo; Masatoshi Takagi
BLOOD, 136, Nov. 2020
Lead - Clinical Feature and Genetic Alterations in Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia and Myeloid/NK Cell Acute Leukemia
Akira Nishimura; Kazuaki Yokoyama; Chika Yamagishi; Takuya Naruto; Tomohiro Morio; Akinori Kanai; Hirotaka Matsui; Naoko Higuchi; Akiko Takada; Haruna Okuno; Shoji Saito; Shuhei Karakawa; Shogo Kobayashi; Hideki Sano; Takashi Koike; Daisuke Hasegawa; Hiroyuki Fujisaki; Daiichiro Hasegawa; Kazutoshi Koike; Atsushi Ogawa; Akitoshi Kinoshita; Norio Shiba; Mizuka Miki; Hideki Nakayama; Yozo Nakazawa; Toshihiko Imamura; Takashi Taga; Souichi Adachi; Katsuyoshi Koh; Atsushi Manabe; Tomohiko Taki; Yasushi Ishida; Arinobu Tojo; Masatoshi Takagi
BLOOD, 132, Nov. 2018
Lead - 抗てんかん薬によりアカシジアが誘発された後頭葉てんかん女児の髄液鉄の検討
柴 直子; 塚原 孝典; 斉藤 章治; 日高 義彦; 本林 光雄; 新美 妙美; 西村 貴文; 石田 岳史; 稲葉 雄二; 小池 健一
脳と発達, 44(4), 346 - 346, Jul. 2012, Not invited
Lead - CD19-Specific T-Cell Therapy for Refractory Philadelphia-Chromosome-Positive Acute Lymphoblastic Leukemia Using PiggyBac Transposon-Based Gene Modification and Low Autoserum-Containing, but Xeno-Free and Tumor Cell Line-Free Culture System
Shoji Saito; Yozo Nakazawa; Miyuki Tanaka; Ryu Yanagisawa; Yasuhiro Maeda; Takeshi Inukai; Kanji Sugita; Matthew H. Wilson; Cliona M. Rooeny; Kenichi Koike
MOLECULAR THERAPY, 20, S184 - S185, May 2012, Not invited
Lead
Lectures, oral presentations, etc.
- A first-in-human clinical trial of GMR CAR-T for CD116+ myeloid malignancies.
Saito S, Nakazawa Y.
第80回日本癌学会, 01 Oct. 2021A first-in-human clinical trial of GMR CAR-T for CD116 + myeloid malignancies.
Saito S, Tanaka M, Hasegawa A, Morokawa H, Hirabayashi K, Inada Y, Kojima S, Usami Y, Yanagisawa R, Nakazawa H, Tashiro H, Yagyu S, Nakazawa Y.
第83回日本血液学会学術集会, 24 Sep. 2021Non-Viral Delivery of Therapeutic mRNA Using Tumor-Tropic Liposomes for the Treatment of Solid Tumors
Saito S, Nakashima I, Akahoshi E, Ishihara-Sugano M, Yagyu S, Nakazawa Y.
American Society of Gene and Cell Therapy 24th Annual meeting, May 2021, Not invited難治性血液腫瘍に対する遺伝子・細胞治療の開発
Shoji Saito
第124回日本小児科学会学術集会, 16 Apr. 2021, InvitedNon-Viral Delivery of Therapeutic mRNA Using Tumor-Tropic Liposomes for the Treatment of Solid Tumors
Shoji Saito; Ikumi Nakashima; Eiichi Akahoshi; Mitsuko Ishihara-Sugano; Shigeki Yagyu; Yozo Nakazawa
MOLECULAR THERAPY, Apr. 2021, CELL PRESSTumor-tropic liposome-mediated therapeutic delivery of mRNA for pediatric / adolescent and young adult cancers
Shoji Saito; Eiichi Akahoshi; Mitsuko Ishihara-Sugano; Shigeki Yagyu; Yozo Nakazawa
CANCER SCIENCE, Feb. 2021, WILEYTumor-Tropic Liposome-Based Delivery of Therapeutic mRNA for T Cell Leukemias
Shoji Saito; Ikumi Nakashima; Aiko Hasegawa; Eiichi Akahoshi; Mitsuko Sugano; Shigeki Yagyu; Yozo Nakazawa
PEDIATRIC BLOOD & CANCER, Dec. 2020, WILEYA First-in-Human Clinical Trial of Novel Chimeric Antigen Receptor T-Cell Therapy Targeting Granulocyte-Macrophage Colony-Stimulating Factor Receptor for Acute Myeloid Leukemia
Shoji Saito; Aiko Hasegawa; Miyuki Tanaka; Hirokazu Morokawa; Daisuke Morita; Yoichi Inada; Shunsuke Kojima; Ryu Yanagisawa; Shigeki Yagyu; Yozo Nakazawa
PEDIATRIC BLOOD & CANCER, Dec. 2020, WILEYMutated GM-CSF-Based CAR T-Cells Targeting CD116/CD131 Complexes Exhibit Enhanced Anti-Tumor Effects Against Acute Myeloid Leukemia
Saito S, Hasegawa A, Nagai M, Inada Y, Morokawa H, Nakashima I, Morita D, Ide Y, Matsuda K, Tashiro H, Yagyu S, Tanaka M, Nakazawa Y
62nd Annual Meeting and Exposition of American Society of Hematology, Dec. 2020, Not invitedTumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
Shoji Saito; Ikumi Nakashima; Aiko Hasegawa; Eiichi Akahoshi; Mitsuko Ishihara-Sugano; Shigeki Yagyu; Yozo Nakazawa
BLOOD, Nov. 2020, AMER SOC HEMATOLOGY,Mutated GM-CSF-Based CAR T-Cells Targeting CD116/CD131 Complexes Exhibit Enhanced Anti-Tumor Effects Against Acute Myeloid Leukemia
Shoji Saito; Aiko Hasegawa; Mika Nagai; Yoichi Inada; Hirokazu Morokawa; Ikumi Nakashima; Daisuke Morita; Yuichiro Ide; Kazuyuki Matsuda; Haruko Tashiro; Shigeki Yagyu; Miyuki Tanaka; Yozo Nakazawa
BLOOD, Nov. 2020, AMER SOC HEMATOLOGY,Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
Shoji Saito, Ikumi Nakashima, Aiko Hasegawa, Eiichi Akahoshi, Mitsuko Ishihara-Sugano, Shigeki Yagyu, and Yozo Nakazawa
ASGCT 23rd Annual Meeting, 12 May 2020Tumor-Tropic Liposome-Mediated Therapeutic Delivery of mRNA for T Cell Malignancies
Shoji Saito; Ikumi Nakashima; Aiko Hasegawa; Eiichi Akahoshi; Mitsuko Ishihara-Sugano; Shigeki Yagyu; Yozo Nakazawa
MOLECULAR THERAPY, Apr. 2020, CELL PRESSTumor-tropic liposome-mediated therapeutic delivery of mRNA for pediatric / adolescent and young adult cancers
Saito S, Nakashima I, Hasegawa A, Akahshi E, Ishihara-Sugano M, Yagyu S, Nakazawa Y
第79回日本癌学会学術集会, Jan. 2020, Hiroshima, Japan, Not invitedPiggyBac-modified GM-CSF receptor-specific CAR-T therapy for acute myeloid leukemia.
Saito S, Hasegawa A, Tanaka M, Morita D, Nakashima I, Morokawa H, Nagai M, Inada Y, Matsuda K, Ide Y, Tashiro H, Yagyu S, Tanaka M, Nakazawa Y
82nd Annual meeting of Japanese Society of Hematology, Jan. 2020, Kyoto, Japan, Not invitedCombining oncolytic viruses with CAR-T cells for the treatment of solid tumors
齋藤章治
第60回小児血液・がん学会学術集会, 15 Nov. 2018, 小児血液・がん学会Combining Oncolytic Viruses with CAR-T Cells for the Treatment of Solid Tumors
Shoji Saito
PEDIATRIC BLOOD & CANCER, Nov. 2018, WILEY臍帯血移植にて長期寛解を維持しているX連鎖リンパ増殖症 type 2の 1例
齋藤章治 中沢洋三 重村倫成 平林耕一 倉田敬 坂下一夫 小池健一 金兼弘和
第55回日本小児血液・がん学会学術集会, 01 Dec. 2013WT1抗原特異的アロ樹状細胞療法によって長期寛解が得られた難治性急性リンパ性白血病の1例
齋藤章治、田中美幸、柳沢龍、坂下一夫、吉川健太郎、倉田敬、平林耕一、中沢洋三、小池健一、下平滋隆
第75回日本血液学会学術集会20, 11 Oct. 2013, Not invitedAffiliated academic society
- Jan. 2017
The Internattional Society of Paediatric Oncology (SIOP) - American Society of Gene & Cell Therapy
- American Society of Hematology
- JAPAN PEDIATRIC SOCIETY
- Japanese Society for Transplantation and Cellular Therapy
- The Japan Society of Transfusion Medicine and Cell Therapy
- Japanse Society of Hematology
- The Japanese Society of Pediatric Hematology and Oncology
Research Themes
- Developing a combinatorial treatment of CAR-T therapy and liposome-based mRNA vaccination for pediatric solid tumors
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Shinshu University
Apr. 2023 - Mar. 2027 - Tumor-tropic liposome-mediated therapeutic delivery of mRNA for the treatment of adolescent and young adult cancers.
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (C)
Shinshu University
Apr. 2020 - Mar. 2023 - がんに対する新規キメラ抗原受容体(CAR)-T細胞療法開発に関する国際共同研究
国立研究開発法人日本医療研究開発機構
2019 - 2022 - Combining oncolytic virus with genetically modified T cell therapy for the treatment of cancer
Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Grant-in-Aid for Early-Career Scientists
Shinshu University
Apr. 2018 - Mar. 2020 - PiggyBac transposon-mediated CD19-specific T cells against Ph+ acute lymphoblastic leukemia
Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B)
Shinshu University
Apr. 2012 - Mar. 2014