
JOSHITA Satoru
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
School of Medicine Department of Medicine
Professor
Researcher Information
Research Keyword
- chronic liver disease, autoimmune liver diseases, immunogenetics, non-invasive diagnostic test, viral hepatitis
Research activity information
Paper
- Higher Responsiveness for Women, High Transaminase Levels, and Fat Percentage to Pemafibrate Treatment for NAFLD
Iwadare T, Kimura T, Kunimoto H, Tanaka N, Wakabayashi SI, Yamazaki T, Okumura T, Kobayashi H, Yamashita Y, Sugiura A, Joshita S, Umemura T
BIOMEDICINES, 10(11), Nov. 2022 - Circulating thrombospondin 2 levels reflect fibrosis severity and disease activity in HCV-infected patients
Iwadare T, Kimura T, Tanaka N, Yamazaki T, Wakabayashi SI, Okumura T, Kobayashi H, Yamashita Y, Pydi SP, Nakajima T, Iwaya M, Sugiura A, Joshita S, Uehara T
Sci Rep, 12(1), 18900, Nov. 2022 - Toward the accumulation of evidence for a novel high-sensitivity hepatitis B core-related antigen assay in patients with hepatitis B virus infection
Joshita, S.
Hepatol Res, 52(9), 743-744, Sep. 2022 - Quantitative changes of lipoprotein(a) in chronic hepatitis C patients achieving a sustained virological response by direct-acting antivirals
Okumura T, Joshita S, Sugiura A, Ota M, Umemura T
Clin Res Hepatol Gastroenterol, 46(8), 102011, Aug. 2022 - The levels of IL-1beta and soluble IL-1 receptors in patients with IgG4-related periaortitis/periarteritis
Ashihara N, Ota M, Fujinaga Y, Ozawa M, Kuraishi Y, Watanabe T, Hamano H, Joshita S, Kawa S, Umemura T
Adv Med Sci, 67(2), 257-261, Jul. 2022 - The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4(+) eosinophils unique to the small intestine
Wang WL, Kasamatsu J, Joshita S, Gilfillan S, Di Luccia B, Panda SK, Kim DH, Desai P, Bando JK, Huang SC, Yomogida K, Hoshino H, Fukushima M, Jacobsen EA, Van Dyken SJ, Ruedl C, Cella M, Colonna M
Proc Natl Acad Sci U S A, 119(23), e2204557119, Jun. 2022 - Clinical practice guidelines for autoimmune hepatitis
Ohira H, Takahashi A, Zeniya M, Abe M, Arinaga-Hino T, Joshita S, Takaki A, Nakamoto N, Kang JH, Suzuki Y, Sogo T, Inui A, Koike K, Harada K, Nakamoto Y, Kondo Y, Genda T, Tsuneyama K, Matsui T, Tanaka A:
Hepatol Res, 52(7), 571-585, May 2022 - Risk factors for relapse of autoimmune hepatitis in Japan: A nationwide survey
Takahashi A, Ohira H, Abe K, Zeniya M, Abe M, Arinaga-Hino T, Nakamoto N, Takaki A, Kang JH, Joshita S, Suzuki Y, Koike K, Inui A, Tanaka A, Japan Autoimmune Hepatitis Study G
Hepatol Res, 52(7), 597-602, Apr. 2022 - IL-33 signaling in sensory neurons promotes dry skin itch
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RWt, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS
J Allergy Clin Immunol, 149(4), 1473-1480, Apr. 2022 - 2-Step PLT16-AST44 method: Simplified liver fibrosis detection system in patients with non-alcoholic fatty liver disease
Fujimori N, Kimura T, Tanaka N, Yamazaki T, Okumura T, Kobayashi H, Wakabayashi SI, Yamashita Y, Sugiura A, Pham J, Pydi SP, Sano K, Joshita S, Umemura T
Hepatol Res, 52(4), 352-363, Jan. 2022 - A Case of Liver Metastasis in Primary Renal Cell Carcinoma Diagnosed by Hepatectomy after 9 Years of Follow-up of Cystic Liver Lesion
SHIMIZU Yuki, SUGIURA Ayumi, JOSHITA Satoru, KOBAYASHI Hiroyuki, WAKABAYASHI Shun-ichi, YAMASHITA Yuki, YAMAZAKI Tomoo, UEHARA Takeshi, SHIMIZU Akira, SOEJIMA Yuji,UMEMURA Takeji
The Shinshu Medical Journal, 69(4), 209-215, Aug. 2021 - Adult Case of Acute Hepatitis Associated with Primary Cytomegalovirus Infection in Remission Phase of Crohn's Disease
YAMAZAKI Tomoo, JOSHITA Satoru, OHNO Kazuyuki, SUGA Tomoaki, KOBAYASHI Hiroyuki, WAKABAYASHI Shun-ichi, YAMASHITA Yuki, SUGIURA Ayumi, UMEMURA Takeji
The Shinshu Medical Journal, 69(3), 127-133, Jun. 2021 - Serum thrombospondin 2 is a novel predictor for the severity in the patients with NAFLD
Kimura T, Tanaka N, Joshita S (8th), et al.
Liver Int., 41(3), 505-514, 20 Jan. 2021, Refereed - The ursodeoxycholic acid response score predicts pathological features in primary biliary cholangitis
Kawata K, Joshita S (2nd), Shimoda S, et al.
Hepatol Res., 51(1), 80-89, 01 Jan. 2021, Refereed - Relationship of early acute complications and insertion site in push method percutaneous endoscopic gastrostomy
Suzuki H (FA), Joshita S (FA), Nagaya T (CA), et al.
Sci Rep, 10(1), 20551, 25 Nov. 2020, Refereed - Clinical utility of steatohepatitis-related FibroScan-aspartate aminotransferase score for predicting hepatocellular carcinoma in chronic hepatitis C virus patients achieving a sustained virological response by direct-acting antivirals
Joshita S (FA), Umemura T (CA).
Alimentary Pharmacology & Therapeutics., 52(7), 1222-1223, 01 Oct. 2020, Refereed - A case report of pancreatic panniculitis due to acute pancreatitis with intraductal papillary mucinous neoplasm
Yamashita Y (FA), Joshita S (CA), Ito T, Maruyama M, Wada S, Umemura T.
BMC Gastroenterol., 20(1), 286, 24 Aug. 2020, Refereed - Clinical impact of normal alanine aminotransferase on direct‐acting antiviral outcome in patients with chronic hepatitis C virus infection
Joshita S (FA), Sugiura A (FA), Umemura T (CA), et al.
JGH Open., 4, 574-581, 01 Aug. 2020, Refereed - A validation study of the Ursodeoxycholic Acid Response Score in Japanese patients with primary biliary cholangitis
Yagi M, Matsumoto K, Joshita S (15th), et al.
Liver Int., 40(8), 1926-1933, 01 Aug. 2020, Refereed - Polymorphism at rs9264942 is associated with HLA-C expression and inflammatory bowel disease in the Japanese
Suzuki H (FA), Joshita S (CA), Hirayama H, et al.
Sci Rep., 10(1), 12424, 24 Jul. 2020, Refereed - Clinical utility of FibroScan as a non-invasive diagnostic test for primary biliary cholangitis.
Joshita S (FA/CA), Yamashita Y, Sugiura A, et al.
J Gastroenterol Hepatol., 35(7), 1208-1214, 01 Jul. 2020, Refereed - Effectiveness of Glecaprevir/Pibrentasvir for Hepatitis C: Real-World Experience and Clinical Features of Retreatment Cases.
Sugiura A (FA), Joshita S (CA), Yamashita Y, et al.
Biomedicines., 8(4), E74, 03 Apr. 2020, Refereed - Clinical In¬fluence of Hepatitis C Virus Eradication by Direct-acting Antivirals on Lipid Levels and “Ningen Dock” Health Check-up Categories in Patients with Chronic Hepatitis C Virus Infection
Joshita S (FA/CA), Sugiura A, Yamazaki T, et al.
Ningen Dock International., 7, 19-25, 01 Mar. 2020, Refereed - KIR/HLA genotypes confer susceptibility and progression in patients with autoimmune hepatitis.
Umemura T, Joshita S (2nd), Saito H, Yoshizawa K, Norman GL, Tanaka E, Ota M.
JHEP Rep., 1(5), 353-360, 25 Oct. 2019, Refereed - Long-term luseogliflozin therapy improves histological activity of non-alcoholic steatohepatitis accompanied by type 2 diabetes mellitus
Fujimori N, Tanaka N, Joshita S (11th), et al.
Clin J Gastroenterol., 13(1), 83-89, 10 Jul. 2019, Refereed - Biochemical and plasma lipid responses to pemafibrate in patients with primary biliary cholangitis
Joshita S (FA/CA), Umemura T, Yamashita Y, et al.
Hepatol Res., 49(10), 1236-1243, 14 Jun. 2019, Refereed - Bezafibrate Improves GLOBE and UK-PBC Scores and Long-Term Outcomes in Patients With Primary Biliary Cholangitis
Honda A, Tanaka A, Joshita S (15th), et al.
Hepatology., 70(6), 2035-2046, 12 Apr. 2019, Refereed - A Case of Adult T-Cell Leukemia/Lymphoma Complicated with Bilateral Chylothorax
Kako S (FA), Joshita S (CA), Matsuo A, et al.
Case Rep Oncol Med., 2019, 8357893, 17 Feb. 2019, Refereed - Improvement of porphyria cutanea tarda following treatment of hepatitis C virus by direct-acting antivirals: A case report.
Nihei T, Kiniwa Y, Joshita S (4th), et al.
J Dermatol., 46(5), E149-E151, 03 Nov. 2018, Refereed - Quantitative analysis of serum chemokines associated with treatment failure of direct-acting antivirals in chronic hepatitis C.
Umemura T, Yamazaki T, Joshita S (3rd), et al.
Cytokine., 111(1), 357-363, 05 Oct. 2018, Refereed - Past history of hepatocellular carcinoma is an independent risk factor of treatment failure in patients with chronic hepatitis C virus infection receiving direct-acting antivirals.
Sugiura A (FA), Joshita S (FA), Umemura T (CA), et al.
J Viral Hepat., 25(12), 1462-1471, 30 Aug. 2018, Refereed - A cis-eQTL of HLA-DPB1 Affects Susceptibility to Type 1 Autoimmune Hepatitis.
Yamazaki T, Umemura T, Joshita S (3rd), et al.
Sci Rep., 8(1), 11924, 09 Aug. 2018, Refereed - Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients.
Komatsu M, Tanaka N, Joshita S (10th), et al .
Hepatol Res., 48(13), 1092-1098, 27 Jul. 2018, Refereed - Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease.
Fujimori N, Umemura T, Joshita S (7th), et al.
World J Gastroenterol., 24(11), 1239-1249, 21 May 2018, Refereed - Salmonella Enteritidis cholecystitis with chronic granulomatous disease.
Yamashita Y, Kimura T, Joshita S (6th). et al.
IDCases., 12(1), 49-52, 14 May 2018, Refereed - KIR2DL2 combined with HLA-C1 confers risk of hepatitis C virus-related hepatocellular carcinoma in younger patients.
Saito H, Umemura T, Joshita S (3rd), et al.
Oncotarget., 9(28), 19650-19661, 13 Apr. 2018, Refereed - Association between KIR-HLA combination and ulcerative colitis and Crohn's disease in a Japanese population.
Saito H, Hirayama A, Joshita S (4th), et al.
PLoS One., 13(4), e0195778, 12 Apr. 2018, Refereed - Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis.
Kimura T, Tanaka N, Joshita S (6th), et al.
World J Gastroenterol., 24(13), 1440-1450, 07 Apr. 2018, Refereed - Changes in serum levels of autotaxin with direct-acting antiviral therapy in patients with chronic hepatitis C.
Yamazaki T (FA), Joshita S (FA), Umemura T (CA), et al.
PLoS One., 13(4), e0195632, 04 Apr. 2018, Refereed - Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey.
Joshita S (FA), Yoshizawa K (CA), Umemura T, et al.
J Gastroenterol., 53(9), 1079-1088, 23 Feb. 2018, Refereed - Emergence of anti-mitochondrial M2 antibody in patient with angioimmunoblastic T-cell lymphoma.
Wakabayashi SI, Kimura T, Joshita S (4th), et al.
Clin J Gastroenterol., 11(4), 302-308, 10 Feb. 2018, Refereed - Two Cases of Primary Biliary Cholangitis with Hepatocellular Carcinoma in a Non-cirrhotic Stage
SUGIURA Ayumi, JOSHITA Satoru, YAMASHITA Yuki, KIMURA Takefumi, YAMAZAKI Tomoo, FUJIMORI Naoyuki, KOMATSU Michiharu, MATSUMOTO Akihiro, KOBAYASHI Shota, UMEMURA Takeji, TANAKA Eiji
The Shinshu Medical Journal, 66(1), 39-49, 10 Feb. 2018 - Renal impairment is associated with increased risk of mortality in patients with cirrhosis: A retrospective cohort study
Umemura T, Joshita S (2nd), Shibata S, et al.
Medicine (Baltimore)., 98(6), e14475, 01 Feb. 2018, Refereed - Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development.
Vainchtein ID, Chin G, Joshita S (12th), et al.
Science., 359(6381), 1269-1273, 01 Feb. 2018, Refereed - Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.
Song WM (FA), Joshita S (FA), Zhou Y, et al.
J Exp Med., 215(3), 745-760, 10 Jan. 2018, Refereed - A case of liver abscess co-infected with Desulfovibrio desulfuricans and Escherichia coli and review of the literature.
Yamazaki T (FA), Joshita S (CA), Kasuga E, et al.
J Infect Chemother., 24(5), 393-397, 18 Dec. 2017, Refereed - Serum autotaxin is a useful liver fibrosis marker in patients with chronic hepatitis B virus infection.
Joshita S (FA), Ichikawa Y (FA), Umemura T (CA), et al.
Hepatol Res., 48(4), 275-285, 04 Dec. 2017, Refereed - Genetics and epigenetics in the pathogenesis of primary biliary cholangitis.
Joshita S (FA/CA), Umemura T, Tanaka E, Ota M.
Clin J Gastroenterol., 11(1), 11-18, 20 Nov. 2017, Refereed - Association of autoimmune hepatitis with Src homology 2 adaptor protein 3 gene polymorphisms in Japanese patients
Umemura T, Joshita S (2nd), Hamano H, et al.
J Hum Genet., 62(11), 963-967, 01 Nov. 2017, Refereed - Cimetidine/lactulose therapy ameliorates erythropoietic protoporphyria-related liver injury
Fujimori N, Komatsu M, Joshita S (13th), et al.
Clin J Gastroenterol., 10(5), 452-458, 01 Oct. 2017, Refereed - Association of Serum Autotaxin Levels with Liver Fibrosis in Patients with Chronic Hepatitis C
Yamazaki T (FA), Joshita S (FA), Umemura T (CA), et al.
Sci Rep., 20(7), 46705, 01 Apr. 2017, Refereed - A Patency Capsule Remained Intact in the Colon over 210 Hours.
Hihara Y, Joshita S (CA), Takahashi T, et al.
2017(2017), 1201404, 22 Feb. 2017, Refereed - Lymphocyte Antigen 75 Polymorphisms Are Associated with Disease Susceptibility and Phenotype in Japanese Patients with Inflammatory Bowel Disease.
Hirayama A, Joshita S (CA), Kitahara K, et al.
Dis Markers., 2016(2016), 6485343, 14 Nov. 2016, Refereed - Serum Wisteria floribunda agglutinin-positive human Mac-2 binding protein may predict liver fibrosis and progression to hepatocellular carcinoma in patients with chronic hepatitis B virus infection.
Ichikawa Y (FA), Joshita S (FA), Umemura T (CA), et al.
Hepatol Res., 47(2), 226-233, 22 Apr. 2016, Refereed - AST/platelet ratio index associates with progression to hepatic failure and correlates with histological fibrosis stage in Japanese patients with primary biliary cirrhosis.
Joshita S (FA/CA), Umemuta T, Ota M, Tanaka E.
J Hepatol., 61(6), 1443-5, 01 Dec. 2014, Refereed - Serum levels of interleukin-22 and hepatitis B core-related antigen are associated with treatment response to entecavir therapy in chronic hepatitis B.
Okuhara S, Umemura T, Joshita S (3rd), et al.
Hepatol Res., 44(10), E172-80, 01 Oct. 2014, Refereed - Characteristics and prediction of hepatitis B e-antigen negative hepatitis following seroconversion in patients with chronic hepatitis B.
Morita S, Matsumoto A, Joshita S (8th), et al.
Hepatol Res., 44(10), E45-53, 01 Oct. 2014, Refereed - KIR3DL1-HLA-Bw4 combination and IL28B polymorphism predict response to Peg-IFN and ribavirin with and without telaprevir in chronic hepatitis C.
Umemura T, Ota M, Joshita S (11th), et al,.
Hum Immunol., 75(8), 822-6, 01 Aug. 2014, Refereed - Laparoscopic findings of congenital hepatic fibrosis: A case report and review of the published work.
Komatsu M, Tanaka N, Joshita S (7th), et al.
Hepatol Res., 44(7), 818-24, 01 Jul. 2014, Refereed - Genetic polymorphism in IFNL4 and response to pegylated interferon-α and ribavirin in Japanese chronic hepatitis C patients.
Nozawa Y, Umemura Y, Joshita S (7th), et al.
Tissue Antigens., 83(1), 45-8, 01 Jan. 2014, Refereed - KIR, HLA, and IL28B variant predict response to antiviral therapy in genotype 1 chronic hepatitis C patients in Japan.
Nozawa Y, Umemura T, Joshita S (3rd), et al.
PLOS ONE, 8(12), e83381, 12 Dec. 2013, Refereed - Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population
Nakamura M, Nishida N, Joshita S (42th), et al.
Am J Hum Genet., 91(4), 721-728, 20 Sep. 2012, Refereed - Super high resolution for single molecule-sequence-based typing of classical HLA loci at the 8-digit level using next generation sequencers
Shiina T, Suzuki S, Joshita S (9th), et al.
Tissue Antigens., 80(4), 305-316, 04 Aug. 2012, Refereed - Long-term outcome of japanese patients with type 1 autoimmune hepatitis
Yoshizawa K, Matsumoto A, Joshita S (5th), et al.
Hepatology., 56(2), 668-676, 06 Jul. 2012, Refereed - Changes in the serum level of hepatitis B virus (HBV) surface antigen over the natural course of HBV infection
Matsumoto A, Tanaka E, Joshita S (LA), et al.
J Gastroenterol., 47(9), 1006-1013, 29 Feb. 2012, Refereed - Genetic polymorphisms in CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients
Aiba Y, Nakamura M, Joshita S (3rd), et al.
J Gastroenterol., 46(10), 1203-1212, 19 May 2011, Refereed - Cytokine profiles affecting the pathogenesis of autoimmune hepatitis in Japanese patients
Kamijo A, Yoshizawa K, Joshita S (3rd), et al.
Hepatol Res., 41(4), 350-357, 24 Feb. 2011, Refereed - Down-regulation of SREBP-1c is associated with the development of burned-out NASH.
Nagaya T, Tanaka N, Joshita S (9th), et al.
J Hepatol., 53(4), 724-31, 01 Jul. 2010, Refereed - Pretreatment prediction of virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients using viral and host factors.
Shirakawa H, Matsumoto A, Joshita S (3rd), et al.
Hepatolgy., 48(6), 1753-60, 01 Dec. 2008, Refereed - Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: a 27-year follow-up case.
Nagaya T, Tanaka N, Joshita S (7th), et al.
Clin J Gastroenterol., 1(3), 116-121, 01 Oct. 2008, Refereed - Thrombotic thrombocytopenic purpura associated with pegylated-interferon alpha-2a by an ADAMTS13 inhibitor in a patient with chronic hepatitis C.
Kitano K, Gibo Y, Joshita S (6th), et al.
Haematologica., 91(8), ECR34, 01 Aug. 2006, Refereed