博士（医学）, 信州大学

Medical, Dental, and Pharmaceutical Science

Boundary Medicine

Others, Laboratory Medicine

1977, Tokyo University of Pharmacy and Life Science, 薬学部

1980, 静岡県立静岡薬科大学, Graduate School, Division of Pharmaceutical Sciences

Altered Serum Lysophosphatidylethanolamine Species Profile in Patients with Autoimmune Pancreatitis
Yamaura Makoto, Hidaka Hiroya
Shinshu Medical Journal, 70(2), 91-100, Apr. 2022

Consumption of Nonfat Milk Results in a Less Atherogenic Lipoprotein Profile: A Pilot Study
Hidaka H, Takiwaki M, Yamashita M, Kawasaki K, Sugano M, Honda T. Hidaka H, Takiwaki M, Yamashita M, Kawasaki K, Sugano M, Honda T
Ann Nutr Metab, 61(2), 111-116, 2012

Mild acid hydrolysis of sphingolipids yields lysosphingolipids: a matrix-assisted laser desorption and ionization time-of-flight mass spectrometry study
Hidaka H, Takiwaki M, Yamashita M, Otsuki S, Kawasaki K, Sugano M, Honda T
J Anal Bio-Sci, 35(3), 241-248, 2012

The Investigators of Study on Prevention of Metabolic Syndrome among Children, Adolescents, and YoungAdults in Shinshu: Association between serum uric acid levels and cardiometabolic risk factors among Japanese junior high school students.
Hongo M, Hidaka H, Sakaguchi S, Nakanishi K, Ichikawa M, Hirota N, Tanaka N, Tsuruta G, Yazaki Y, Kinoshita O, Ikeda U, Koike K,
Circ J, 74, 1570-1577, 2010

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients.
Fukumoto H, Tokuda T, Kasai T, Ishigami N, Hidaka H, Kondo M, Allsop D, Nakagawa M.
FASEB J, 24(8), 2716-2726, 2010

透析患者におけるホモシステインと透析療法の検討
3. 塩澤　勉、中村啓章、田村克彦、長澤正樹、羽生　登、本田孝行、日高宏哉
腎と透析, 69, 164-169, 2010

Characterization of cysteine and homocysteine bound to human serum transthyretin.
Hanyu N, Shimizu T, Yamauchi K, Okumura N, Hidaka H.
Clin Chim Acta., 403(1-2), 70-75, 2009

一般中学生の高尿酸血症と生活習慣病との関連
本郷 実、日高宏哉、阪口しげ子、市川元基、池田宇一、田中直樹、鶴田悟郎、小池健一,
33, 17-26, 2009

Fluvastatin improves arterial stiffness in patients with coronary artery disease and hyperlipidemia: a 5-year follow-up study.
Hongo M, Tsutsui H, Mawatari E, Hidaka H, Kumazaki S, Yazaki Y, Takahashi M, Kinoshita O, Ikeda U.
Circ J., 72(5), 722-728, 2008

Specific, rapid, and sensitive enzymatic measurement of sphingomyelin, phosphatidylcholine and lysophosphatidylcholine in serum and lipid extracts.
Hidaka H, Yamauchi K, Ohta H, Akamatsu T, Honda T, Katsuyama T.
Clin Biochem., 41(14-15), 1211-1217, 2008

Analysis of human serum lipoprotein lipidcomposition using MALDI-TOF mass spectrometry.
Hidaka H, Hanyu N, Sugano M, Kawasaki K, Yamauchi K, Katsuyama T.
Ann Clin Lab Sci., 37(3), 213-221, 2007

Degradation of pre-beta-high density lipoproteins and their binding activity to human blood monocytes
Nakabayashi T, Yamauchi K, Sugano M, Sano K, Tozuka M, Hidaka H
Ann Clin Lab Sci, 34, 287-298, 2004

Purification and measurement of HDL3-binding proteins in human peripheral blood mononuclear cells
Hidaka H, Tozuka M, Yamauchi K, Ohta H, Nakayama J, Katsuyama T
Ann Clin Lab Sci, 33, 271-278, 2003

Purification and measurement of HDL3-binding proteins present in human peripheral monocytes.
Hiroya Hidaka, Minoru Tozuka, Kazuyoshi Yamauchi, Hiroyoshi Ohta,Jun Nakayama, and Tsutomu Katsuyama
Annals of clinical&laboratory science, 33(3), 2003

Detection of monoclonal immunoglobulin by serum protein electrophoresis of samples from patient of Shinonoi General Hospital from 1992-2001
Hanyu N, Kawaguchi K, Hshizume S, Shimizu T, Tozuka M, Fujita K, Hidaka H
Jornal of Analytical Bio-Science, 26, 422-427, 2003

Characterization of triglyceride rich lipoproteins with very light density by ultracentrifugation and agarose gel electrophoresis using triglyceride- and cholesterol-staining
Hiroya Hidaka, Minoru Tozuka, Barbara Meyer, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Tetsuo Nakabayashi, and Tsutomu Katsuyama.
Annals of clinical&laboratory science, 33(2), 167-178, 2003

自動生化学分析機を用いた免疫比濁法による血清および髄液中トランスサイレチンの測定
笹野桂子、日高宏哉、菅野光俊、鈴木剛史、広仲英治、戸塚　実
医学検査, 51(8), 1146-1149, 2002

栄養アセスメント蛋白の測定法．－アルブ-ン，トランスフェリン，トランスサイレチン，レチノール結合蛋白－
日高宏哉，戸塚　実
検査と技術, 30, 1377-1382, 2002

Isoform-specific effect of apolipoprotein E on endocytosis of beta-amyloid in cultures of neuroblastoma cells.
Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka,Tetsuo Nakabayashi , Mitsutoshi Sugano, and Tsutomu Katsuyama
Annals of clinical&laboratory science, 32(1), 65-74, 2002

Predominant apolipoprotein J exists as lipid-poor mixtures in cerebrospinal fluid
Takefumi Suzuki,Minoru Tozuka, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Testuo Nakabayashi, Nobuo Okumura, Hiroya Hidaka, Tshutomu Katsuyama
Ann Clin Lab Sci, 32(4), 369-376, 2002

Analysis of hemoglobin and globin chain variants by a commonly used capillary isoelctric focusing method
Mitsutoshi Sugano, Hiroya Hidaka,Kazuyoshi Yamauchi, Tetsuo Nakabayashi,Yumiko Higuchi,Kiyotaka Fujita, Nobuo Okumura, Yoshihisa Ushiyama, Minoru Tozuka, and Tshutomu Katsuyama T.
Electrophoresis, 21, 3016-3019, 2001

Confirmation of minor components of less polar neutral and acidic glycolipids in monkey brain tissue.
Tamotsu Taketomi,Eiko Sugiyama, Kei-ichi Uemura, Atsushi Hara, Hiroya Hidaka, Minoru Tozuka,Tetsuo Nakabayashi, and Tsutomu Katsuyama.
Journal of Lipid Research, 42, 873-885, 2001

リポ蛋白分画中の脂質組成の分析
日高宏哉、山内一由、戸塚　実
検査と技術, 29(9), 1053-1059, 2001

Size-related and size-unrelated functional heterogeneity among pancreatic islets
Toru Aizawa, Tsuyoshi Kaneko, Keishi Yamauchi, Hiroki Yajima, Tomoko Nishizawa, Toshihiko Yada, Hiroshi Matsukawa, Minoru Nagai, Satoko Yamada, Yoshihiko Sato, Mitsuhisa Komatsu, Nobuo Itoh, Hiroya Hidaka, Yoshitaka Kajimoto and Kiyoshi Hashizume
Life Science, 69, 2627-2639, 2001

LDアイソザイムの測定
羽生　登、清水敏夫、日高宏哉
検査と技術, 29(12), 1329-1336, 2001

過去５年間、血清蛋白電気泳動法により検出されたM蛋白の集計
羽生　登、橋詰幸子、田中順子、永井久美子、清水敏夫、戸塚　実、日高宏哉
医学検査, 50(8), 1037-1041, 2001

酵素法による液状カルシウム測定試薬「ダイヤカラー・リキッドCa」の基礎的検討
菅野光俊、日高宏哉、鈴木剛史、笹野桂子、広仲英治、野本昭三、戸塚　実
現代医療., 33, 134-138, 2001

Characterization of an apolipoprotein E3 variant (Arg 145 ->His) associated with mild hypertriglyceridemia
Hidaka, H; Tozuka, M; Hidaka, E; Yamauchi, K; Ota, H; Honda, T; Katsuyama, T
ANNALS OF CLINICAL AND LABORATORY SCIENCE, 31(2), 163-170, 2001

Helicobacter pylori and two ultrastructurally distinct layers of gastric mucous cell mucins in the surface mucous gel layer
Eiko Hidaka, Hiroyoshi Ota, Hiroya Hidaka, Masayoshi Hayama, Taiji Akamatsu, Jun Nakayama and Tsutomu Katsuyama
Gut., 49(4), 474-480, 2001

Evaluation of the automatic fluorescent image analyzer,Image Titer, for quantitative analysis of antinuclear antibodies
Tetsuo Nakabayashi, Toshiko Kumagai, Kazuyoshi Yamauchi, Mitsutoshi Sugano, Kiyptaka Fujita, Hiroya Hidaka, Minoru Tozuka
Journal of Clin Pathology, 115(3), 424-429, 2001

Cell Lineage Specificity of Newly Raised Monoclonal Antibodies Against Gastric Mucins in Normal, Metaplastic and Neoplastic Human Tissues and Their Application for Pathology Diagnosis.
Hiroyoshi Ota, Masayoshi Hayama, Jun Nakayama, Hiroya Hidaka, Takayuki Honda, Keiko Ishii, Mana Fukushima, Takeshi Uehara, Makoto Kurihara, Kazuhiko Ishihara, Kyoko Hotta, Tsutomu Katsuyama
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 115(1), 69-79, 2001

Relation of Helicobacter pylori to mucins and mucouscells in human stomach.
Eiko Hidaka, Hiroyashi Ota, Masayoshi Hayama, Hiroya Hidaka, Keiko Ishii, Kosei Nakajima, Akihiko Yoshizawa, Tsutomu Katsuyama
Journal of Cell Molecular Medicine, 4(3), 224-225, 2000

合成基質を用いた液状リパ－ゼ測定試薬の検討
菅野光俊、山内一由、広仲英治、中林徹雄、日高宏哉、戸塚　実
医学検査, 49, 1608-1611, 2000

イムノクロマトグラフィー法による感染症簡易検出キットの緊急検査適用についての検討-HBs抗原、HBs抗体およびTP抗体検出キットについて
浜　尚枝、中林徹雄，熊谷俊子、日高宏哉，戸塚　実
医学検査, 49(2), 150-154, 2000

Effect of apolipoprotein AII on the interaction of apolipoprotein E with beta-amyloid: some apo(E-AII) complexes inhibit the internalization of beta-amyloid in cultures of neuroblastoma cells.
Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka, Tetsuo Nakabayashi, Mitsutoshi Sugano, KondoYoshiyuki, Akira Nakagawara, and Tshutomu Katsuyama
Journal of Neuroscience Research, 62(4), 608-614, 2000

Coexistence of gland mucous cell-type mucin and lysozyme in gastric gland mucous cells
Eiko Hidaka, Hiroyoshi Ota, Tsutomu Katsuyama, Jun Nakayama , Masanobu Momose, Hiroya Hidaka, Keiko Ishii, Fusayoshi Murata, Shinichiro Tsuyama, Makoto Kurihata, Kazuhiko Ishihara, Kyoko Hotta
Histochem Biol Cell, 113(2), 91-98, 2000

The identification of specific high density lipoprotein3 binding sites on human blood monocytes using fluorescence-labeled ligand.
Hiroya Hidaka, Eiko Hidaka,Minoru Tozuka,Jun Nakayama, Tsutomu Katsuyama, and Noel Fidge
Journal of Lipid Research, 40(6), 1131-1139, 1999

Characterization of apolipoprotein E-containing lipoproteins in cerebrospinal fluid: eddect of phenotype on the distribution of apolipoprotein E
Kazuyoshi Yamauchi, Minoru Tozuka, Hiroya Hidaka, Eiko Hidaka, Yoshiyuki Kondo, and Tsutomu Katsuyama
CLINICAL CHEMISTRY, 45(9), 1431-1438, 1999

Higher avidity binding of apolipoprotein (E-AII) complex than of apolipoprotein E monomer to beta-amyloid
Kazuyoshi Yamauchi, Minoru Tozuka, Tetsuo Nakabayashi, Mitsutoshi Sugano, Hiroya Hidaka, Yoshiyuki Kondo, Tsutomu Katsuyama
JOURNAL OF NEUROSCIENCE RESEARCH, 58(2), 301-307, 1999

Genetic analyses in homozygous and heterozygous variants of lactate dehydrogenase-B(H) subunit-LD-B Matsumoto I and II (LD-B W323R)
Nobuo Okumura, Fumiko Terasawa, Ichiro Ueno, Keiko Oki, Kazuyoshi Yamauchi, Hiroya Hidaka, Minoru Tozuka, Mitsue Okura, Tsutomu Katsuyama
Clinical Chimica Acta, 287(1-2), 163-171, 1999

Japanese Society of Laboratory Medicine

Japabese Association of Medical Technology

Japan Atherosclerosis Society

The Society of Analytical Bio-Science

Japan Society of Clinical Chemistry

炎症性腸管疾患の脂質及びアポ蛋白代謝機序と質量分析による病態指標検査法の開発
科学研究費補助金, 基盤研究（C）
2008 - 2010

炎症性腸管疾患の血清脂質とアポ蛋白の代謝機序を解明するための質量分析法の開発
科学研究費補助金, 萌芽研究
2006 - 2007

The elucidation of the mechanism of lipidosis
2003

Adipose intestinal absorption and metabolism
2003

Analysis of HDL-binding proteins
2003

Young life-style related diseases prevention and education
2003

Quality management of clinical laboratory tests
2003

Laboratory assessment of nutrition management
2003

Analysis of phospholipid by mass spectrometry
1995

Denaturation of the apolipoprotein
1995

Analysis and metabolism of high density lipoprotein (HDL)
1989