Kamiyoshi Akiko
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
Interdisciplinary Cluster for Cutting Edge Research Institute for Biomedical Sciences
Assistant Professor
Researcher Information
Research Keyword
- metabolism
Career
Educational Background
Research activity information
Paper
- Receptor activity-modifying proteins of adrenomedullin (RAMP2/3): Roles in the pathogenesis of ARDS
Kasahara T, Tanaka M, Zhao Y, Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Kawate H, Matsuda Y, Zhang Y, Guo Q, Li P, Hoshiyama K, Li J, Onishi N, Hayashi M, Sanjo H, Ishida K, Tanaka S, Kawamata M, Shindo T
Peptides, 171, 171118, Jan. 2024 - Role of adrenomedullin 2/Intermedin in the pathogenesis of neovascular age-related macular degeneration
Kakihara S, Matsuda Y, Hirabayashi K, Imai A, Iesato Y, Sakurai T, Kamiyoshi A, Tanaka M, Ichikawa-Shindo Y, Kawate H, Zhao Y, Zhang Y, Guo Q, Li P, Onishi N, Murata T, Shindo T
Lab Invest, 103(4), 100038, Apr. 2023 - Receptor activity modifying protein RAMP sub-isoforms and their functional differentiation, which regulates functional diversity of adrenomedullin
Shindo T, Tanaka M, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Sakurai T.
Biology, 11(5), 788, May 2022 - Adrenomedullin ameliorates pulmonary fibrosis by regulating TGF-b-Smads signaling and myofibroblast differentiation
Wei Y, Tanaka M, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Cui N, Kakihara S, Zhao Y, Aruga K, Sanjo H, Shindo T.
Endocrinology, 162(8), bqab090, Aug. 2021 - Adrenomedullin-Receptor Activity-Modifying Protein 2 System Ameliorates Subretinal Fibrosis by Suppressing Epithelial-Mesenchymal Transition in Age-Related Macular Degeneration
Tanaka M, Kakihara S, Hirabayashi K, Imai A, Toriyama Y, Iesato Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Cui N, Wei Y, Zhao Y, Aruga K, Yamauchi A, Murata T, Shindo T.
Am J Pathol, 191(4), 652-668, Apr. 2021 - Adrenomedullin-RAMP2 and -RAMP3 Systems Regulate Cardiac Homeostasis during Cardiovascular Stress
Cui N, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Tanaka M, Wei Y, Kakihara S, Zhao Y, Aruga K, Kawagishi H, Nakada T, Yamada M, Shindo T.
Endocrinology, 162(3), bqab001, Mar. 2021 - Deficiency of the adrenomedullin-RAMP3 system suppresses metastasis through the modification of cancer-associated fibroblasts
Dai K, Tanaka M, Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Kawate H, Cui N, Wei Y, Tanaka M, Kakihara S, Matsui S, Shindo T.
Oncogene, 39(9), 1914-1930, Feb. 2020 - Production of genetically engineered mice with higher efficiency, lower mosaicism, and multiplexing capability using maternally expressed Cas9
Sakurai T, Kamiyoshi A, Kawate H, Watanabe S, Sato M, Shindo T.
Sci Rep, 10(1), 1091, Jan. 2020 - Endogenous Calcitonin Gene-Related Peptide Deficiency Exacerbates Postoperative Lymphedema by Suppressing Lymphatic Capillary Formation and M2 Macrophage Accumulation
Matsui S, Tanaka M, Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Kawate H, Dai K, Cui N, Wei Y, Tanaka M, Kakihara S, Nakamura K, Yamauchi A, Ishida K, Tanaka S, Kawamata M, Shindo T.
Am J Pathol, 189(12), 2487-2502, Dec. 2019 - Bindel-PCR: a novel and convenient method for identifying CRISPR/Cas9-induced biallelic mutants through modified PCR using Thermus aquaticus DNA polymerase
Sakurai T, Kamiyoshi A, Takei N, Watanabe S, Sato M, Shindo T.
Sci Rep, 9(1), 9923, 09 Jul. 2019 - Development of a Novel Model of Central Retinal Vascular Occlusion and the Therapeutic Potential of the Adrenomedullin-Receptor Activity-Modifying Protein 2 System
Hirabayashi, Kazutaka; Tanaka, Masaaki; Imai, Akira; Toriyama, Yuichi; Iesato, Yasuhiro; Sakurai, Takayuki; Kamiyoshi, Akiko; Ichikawa-Shindo, Yuka; Kawate, Hisaka; Tanaka, Megumu; Dai, Kun; Cui, Nanqi; Wei, Yangxuan; Nakamura, Keisei; Iida, Shiho; Matsui, Shuhei; Yamauchi, Akihiro; Murata, Toshinori; Shindo, Takayuki;
AMERICAN JOURNAL OF PATHOLOGY, 189(2), 449-466, Feb. 2019
- Regulation of cardiovascular development and homeostasis by the adrenomedullin-RAMP system
Shindo, Takayuki; Tanaka, Megumu; Kamiyoshi, Akiko; Ichikawa-Shindo, Yuka; Kawate, Hisaka; Yamauchi, Akihiro; Sakurai, Takayuki;
PEPTIDES, 111, 55-61, Jan. 2019 - RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders
Liu, Teng; Kamiyoshi, Akiko; Tanaka, Megumu; Iida, Shiho; Sakurai, Takayuki; Ichikawa-Shindo, Yuka; Kawate, Hisaka; Hirabayashi, Kazutaka; Dai, Kun; Cui, Nanqi; Tanaka, Masaaki; Wei, Yangxuan; Nakamura, Keisei; Matsui, Shuhei; Yamauchi, Akihiro; Shindo, Takayuki;
PEPTIDES, 110, 10-18, Dec. 2018 - Endogenous calcitonin gene-related peptide suppresses ischemic brain injuries and progression of cognitive decline.
Zhai L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Xian X, Hirabayashi K, Dai K, Cui N, Tanimura K, Liu T, Wei Y, Tanaka M, Tomiyama H, Yamauchi A, Igarashi K, Shindo T.
J Hypertens, 36(4), 876-891, Apr. 2018 - Placental extract ameliorates non-alcoholic steatohepatitis (NASH) by exerting protective effects on endothelial cells.
Yamauchi A, Kamiyoshi A, Koyama T, Iinuma N, Yamaguchi S, Miyazaki H, Hirano E, Kaku T, Shindo T.
Heliyon, 3(9), e00416, 27 Sep. 2017 - Adrenomedullin Suppresses Vascular Endothelial Growth Factor-Induced Vascular Hyperpermeability and Inflammation in Retinopathy.
Imai A, Toriyama Y, Iesato Y, Hirabayashi K, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Tanaka M, Liu T, Xian X, Zhai L, Dai K, Tanimura K, Liu T, Cui N, Yamauchi A, Murata T, Shindo T.
Am J Pathol, 187(5), 999-1015, May 2017 - Vasoprotective Activities of the Adrenomedullin-RAMP2 System in Endothelial Cells.
Xian X, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Tanaka M, Koyama T, Kawate H, Yang L, Liu T, Imai A, Zhai L, Hirabayashi K, Dai K, Tanimura K, Liu T, Cui N, Igarashi K, Yamauchi A, Shindo T.
Endocrinology, 158(5), 1359-1372, May 2017 - Endogenous Calcitonin Gene-Related Peptide Regulates Lipid Metabolism and Energy Homeostasis in Male Mice.
Liu T, Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Kawate H, Yang L, Tanaka M, Xian X, Imai A, Zhai L, Hirabayashi K, Dai K, Tanimura K, Liu T, Cui N, Igarashi K, Yamauchi A, Shindo T.
Endocrinology, 158(5), 1194-1206, May 2017 - A non-inheritable maternal Cas9-based multiple-gene editing system in mice
Sakurai T, Kamiyoshi A, Kawate H, Mori C, Watanabe S, Tanaka M, Uetake R, Sato M, Shindo T
Sci Rep, 6(20011), 2016 - The endothelial adrenomedullin-RAMP2 system regulates vascular integrity and suppresses tumor metastasis
Tanaka M, Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Liu T, Xian X, Imai A, Zhai L, Hirabayashi K, Owa S, Yamauchi A, Igarashi K, Taniguchi S, Shindo T
Cardiovasc Res, 111(4), 398-409, 2016 - Pathophysiological Function of Endogenous Calcitonin Gene-Related Peptide in Ocular Vascular Diseases
Toriyama Y, Iesato Y, Imai A, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Igarashi K, Tanaka M, Liu T, Xian X, Zhai L, Owa S, Murata T, Shindo T
Am J Pathol, 185(6), 1783-94, 2015 - Adrenomedullin-RAMP2 System in Vascular Endothelial Cells
Koyama T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Shindo T
J Atheroscler Thromb, 22(7), 647-53, 2015 - A single blastocyst assay optimized for detecting CRISPR/Cas9 system-induced indel mutations in mice
Sakurai T, Watanabe S, Kamiyoshi A, Sato M, Shindo T
BMC Biotechnol, 14, 69, 2014 - Adrenomedullin-RAMP2 System Suppresses ER Stress-Induced Tubule Cell Death and Is Involved in Kidney Protection
Uetake R, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Yoshizawa T, Koyama T, Yang L, Toriyama Y, Yamauchi A, Igarashi K, Tanaka M, Kuwabara T, Mori K, Yanagita M, Mukoyama M, Shindo T
PLOS ONE, 9(2), e87667, 2014 - Pathophysiological roles of adrenomedullin-RAMP2 system in acute and chronic cerebral ischemia
Igarashi K, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Toriyama Y, Tanaka M, Liu T, Xian X, Imai A, Zhai L. Owa S, Koyama T, Uetake R, Ihara M, Shindo T
PEPTIDES, 62, 21-31, 2014 - Functional differentiation of RAMP2 and RAMP3 in their regulation of the vascular system
Yamauchi A, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Igarashi K, Toriyama Y, Tanaka M, Liu T, Xian X, Imai A, Zhai L, Owa S, Arai T, Shindo T
J Mol Cell Cardiol, 77, 73-85, 2014 - Vascular Endothelial Adrenomedullin-RAMP2 System Is Essential for Vascular Integrity and Organ Homeostasis
Koyama T, Ochoa-Callejero L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Arai T, Yoshizawa T, Iesato Y, Lei Y, Uetake R, Okimura A, Yamauchi A, Tanaka M, Igarashi K, Toriyama Y, Kawate H, Adams RH, Kawakami H, Mochizuki N, Martinez A, Shindo T
Circulation, 127(7), 842-853, 2013 - Novel Regulation of Cardiac Metabolism and Homeostasis by the Adrenomedullin-Receptor Activity-Modifying Protein 2 System
Yoshizawa T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Koyama T, Uetake R, Yang L, Yamauchi A, Tanaka M, Toriyama Y, Igarashi K, Nakada T, Kashihara T, Yamada M, Kawakami H, Nakanishi H, Taguchi R, Nakanishi T, Akazawa H, Shindo T
Hypertension, 61(2), 341-351, 2013 - Endogenous CGRP protects against neointimal hyperplasia following wire-induced vascular injury
Yang L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yoshizawa T, Koyama T, Iesato Y, Uetake R, Yamauchi A, Tanaka M, Toriyama Y, Igarashi K, Shindo T
J Mol Cell Cardiol, 59, 55-66, 2013 - Adrenomedullin-RAMP2 System Is Crucially Involved in Retinal Angiogenesis
Iesato Y, Toriyama Y, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yoshizawa T, Koyama T, Uetake R, Yang L, Yamauchi A, Tanaka M, Igarashi K, Murata T, Shindo T
Am J Pathol, 182(6), 2380-2390, 2013 - Regulation of adrenomedullin and its family peptide by RAMP system--lessons from genetically engineered mice
Shindo T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Shimoyama N, Iinuma N, Arai T, Miyagawa S
Curr Protein Pept Sci, 14(5), 347-357, 2013
- Adrenomedullin-RAMP2 system in cardiovascular development and homeostasis
Shindo T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y
Current Hypertension Reviews, 7, 217-227, 2011 - Induction of LYVE-1/stabilin-2-positive liver sinusoidal endothelial-like cells from embryoid bodies by modulation of adrenomedullin-RAMP2 signaling
Arai T, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Iesato Y, Koyama T, Yoshizawa T, Uetake R, Yamauchi A, Yang L, Kawate H, Ogawa S, Kobayashi A, Miyagawa S, Shindo T
PEPTIDES, 32(9), 1855-1865, 2011 - Adrenomedullin in sinusoidal endothelial cells play protective roles against cold injury of liver
Iinuma N, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Arai T, Yoshizawa T, Koyama T, Uetake R, Kawate H, Muto S, Tagawa Y, Miyagawa S, Shindo T
PEPTIDES, 31(5), 865-871, 2010 - Endogenous a-calcitonin gene-related peptide mitigates liver fibrosis in chronic hepatitis induced byrepeated administration of concanavalin A
Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Iinuma N, Kawate H, Yoshizawa T, Koyama T, Muto S, Shindo T
Liver Int, 29(5), 642-649, 2009 - GPCRmodulator protein RAMP2 is essential for angiogenesis and vascular integrity
Ichikawa-Shindo Y, Sakurai T, Kamiyoshi A, Kawate H, Iinuma N, Yoshizawa T, Koyama T, Fukuchi J, Iimuro S, Moriyama N, Kawakami H, Murata T, Kangawa K, Nagai R, Shindo T
J Clin Invest, 118(1), 29-39, 2008 - Rapid zygosity determination in mice by SYBR Green real-time genomic PCR of a crude DNA solution
Sakurai T, Kamiyoshi A, Watanabe S, Sato M, Shindo T
Transgenic Res, 17(1), 149-155, 2008 - Endogenous alphaCGRP protects against concanavalin A-induced hepatitis in mice
Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Fukuchi J, Kawate H, Muto S, Tagawa Y, Shindo T
Biochem Biophys Res Commun, 343(1), 152-158, 2006 - Azelnidipine, a long-acting dihydropyridine calcium channel blocker, suppresses the development of cardiac hypertrophy and fibrosis in adrenomedullin knock out mice.
Shindo T, Niu P, Kamiyoshi A, Sakurai T, Ichikawa Y, Iinuma N, Kawate H
Circulation, 114(18), 13-13, 2006 - Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system
Tsutsui M, Ogawa S, Inada Y, Tomioka E, Kamiyoshi A, Tanaka S, Kishida T, Nishiyama M, Murakami M, Kuroda J, Hashikura Y, Miyagawa S, Satoh F, Shibata N, Tagawa Y
Drug Metabolism and Disposition, 34(4), 696-701, 2006 - Effect of zinc on hepatoprotectivity of a1-acid glycoprotein
Kawase M, Kagaya N, Kamiyoshi A, Tagawa Y, Yagi K
Biomedical Research on Trace Elements, 16(4), 299-301, 2005 - Suppression of cell death in primary rat hepatocytes by a1-acid glycoprotein
Kagaya N, Kamiyoshi A, Tagawa Y, Akamatsu S, Isoda K, Kawase M, Yagi K
J Biosci Bioeng, 99(1), 81-83, 2005 - Interaction of rubratoxin B with serum albumin
Kagaya N, Kamiyoshi A, Tagawa Y, Nagashima H, Kawase M, Yagi K
Mycotoxins, 55(1), 23-26, 2005 - Tea catechin, epigallocatechin-3-gallate, inhibits rubratoxin B-induced apoptosis of hepatocytes through MAPK p38 pathway
Kagaya N, Kamiyoshi A, Tagawa Y, Nagashima H, Kawase M, Yagi K
Mycotoxins, 55(1), 17-22, 2005 - Liver organogenesis from murine embryonic stem cells - A substitute system for an animal experiment
Ogawa S, Tagawa Y, Kamiyoshi A, Motoyama H, Tsutsui M, Sato F, Nishiyama M, Nakayama J, Hashikura Y, Miyagawa S
Hepatology, 42(4), 746A-747A, 2005 - Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system
Ogawa S, Tagawa Y, Kamiyoshi A, Suzuki A, Nakayama J, Hashikura Y, Miyagawa S
Stem Cells, 23(7), 903-913, 2005 - Liver protection by bis(maltolato)zinc(II) complex
Kawase M, Kagaya N, Akamatsu S, Kamiyoshi A, Muto S, Tagawa Y, Yagi K
Exp Anim, 53(1), 1-9, 2004 - Novel function of rare catechin, epigallocatechin-3-(3"-O-methyl)gallate, against cold injury in primary rat hepatocytes
Kagaya N, Hara Y, Saijo R, Kamiyoshi A, Tagawa Y, Kawase M, Yagi K
J Biosci Bioeng, 96(6), 559-563, 2003 - Survival and function of mouse embryonic stem cell-derived cardiomyocytes in ectopic transplants
Johkura K, Cui L, Suzuki A, Teng RF, Kamiyoshi A, Okamura S, Kubota S, Zhao X, Asanuma K, Okouchi Y, Ogiwara N, Tagawa Y, Sasaki K
Cardiovascular Research, 58(2), 435-443, 2003
