Kiniwa Yukiko
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
School of Medicine Department of Dermatology
Associate Professor
Researcher Information
Career
- 2018
Associate Professor - 2006 - 2011
Shinshu University School of Medicine - 2003 - 2006
Post doctoral associate, Center for Cell and Gene Therapy, Baylor College of Medicine - 2000 - 2003
信州大学医学部皮膚科 医員 - 2000 - 2003
Shinshu University School of Medicine - 1998 - 2000
Keio University School of Medicine - 1995 - 1996
長野赤十字病院皮膚科 - 1993 - 1998
Shinshu University School of Medicine
Educational Background
Research activity information
Paper
- PIK3CA mutation status in apocrine carcinoma arising in apocrine gland hyperplasia/apocrine nevus: A study of four cases.
Goto K, Kiniwa Y, Hishima T, Honma K, Matsushita S, Aoki M, Nishihara K, Hiraki T.
J Cutan Pathol, 51(6), 399-402, Jun. 2024, Refereed
- Recurrent GATA3 P409Afs*99 Frameshift Extension Mutations in Sweat-gland Carcinoma With Neuroendocrine Differentiation.
Goto K, Kiniwa Y, Yoji Kukita, Shuichi Ohe, Tsubasa Hiraki, Tsunekazu Hishima, Toshihiro Takai, Keiichiro Honma.
Am J Surg Pathol, 48(5), 528-537, May 2024 - A case of acquired idiopathic generalized anhidrosis with perspiration maintained at sites of brodalumab injection to treat psoriasis vulgaris.
Mikoshiba A, Katsuie S, Satake K, Kitamura S, Sato Y, Kiniwa Y, Sano K, Okuyama R.
J Dermatol, 51(5), e160-e161, May 2024 - 皮膚の悪性腫瘍-研究と診療の進歩】乳房外パジェット病の臨床と研究の最前線．
中村 瞳、木庭幸子、奥山隆平
医学のあゆみ, 289(7), 496-501, May 2024
Corresponding - 皮膚がんの診断と検査Update（ダーモスコピー，リキッドバイオプシー）
木庭幸子
癌と化学療法, 51(4), 393-397, Apr. 2024
Lead - Recent treatment and prognosis in 643 patients with extramammary Paget’s disease.
Hatta N, Ogata D, Asai J, Maekawa T, Ito T, Takenouchi T, Kiniwa Y, Miyashita A, Miyagawa T, Muto I, Yamamoto Y, Nagano T, Kiyohara Y, Nakano E, Ohe S, Yamaguchi B, Fukuyama M, Matsuya T, Tsutsumida A, Namikawa K, Yamazaki N.
Exp Dermatol, 33(2), e15030, Feb. 2024 - Linear IgA bullous dermatosis in association with nodal peripheral T cell lymphoma with a T follicular helper phenotype and multiple myeloma: A case report and a literature review.
Masuda M, Kiniwa Y, Mikoshiba A, Kasuga M, Nishina S, Oguchi M, Ishii N, Okuyama R.
Eur J Dermatol, 33(6), 688-689, Dec. 2023, Refereed
Corresponding - Antiplatelet drugs may increase the risk for checkpoint inhibitor-related pneumonitis in advanced cancer patients.
Araki T, Kanda S, Ide T, Sonehara K, Komatsu M, Tateishi K, Minagawa T, Kiniwa Y, Kawakami S, Nomura S, Okuyama R, Hanaoka M, Koizumi T.
ESMO Open, 8(6), 102030, Oct. 2023, Refereed - Efficacy of salvage therapies for advanced acral melanoma after anti-PD-1 monotherapy failure: a multicenter retrospective study of 108 Japanese patients
Mori T; Namikawa K; Yamazaki N; Kiniwa Y; Yamasaki O; Yoshikawa S; Inozume T; Kato H; Nakai Y; Fukushima S; Takenouchi T; Maekawa T; Matsushita S ; Otsuka A; Nomura M ; Baba N; Isei T; Saito S; Fujimoto N; Tanaka R; Kaneko T; Kuwatsuka Y; Matsuya T ; Nagase K; Onishi M; Onuma T ; Nakamura Y
Frontier in Medicine, 10, 23 Aug. 2023, Refereed - Case of autosomal recessive woolly hair/hypotrichosis with compound heterozygous mutations in the LIPH gene at c.742C > A and c.614A > G: The first Japanese case
Yamaguchi N, Kiniwa Y, Hayashi R, Abe R, Katsuie S, Okuyama R.
The Journal of Dermatology, 50(8), e238-e239, Aug. 2023, Refereed - Combined use of nivolumab and ipilimumab among Japanese melanoma patients: Multi-center, retrospective study of 111 cases.
Fujisawa Y, Namikawa K, Yoshino K, Kiniwa Y, Ito T, Kato H, Matsushita S, Hoashi T, Nakamura Y, Yoshikawa S, Miyagawa T, Asai J, Matsuya T, Fukushima S, Kato J, Takenouchi T, Uchi H, Masuzawa M, Yanagi T, Maekawa T.
Br J Dermatol, 223-250, Jul. 2023 - Clinical features of pagetoid spread: Analysis of perianal lesions associated with anal canal adenocarcinoma and perianal primary extramammary Paget disease
Megumi Kosano, Yukiko Kiniwa, Asuka Mikoshiba, Mai Iwaya, Ryuhei Okuyama
The Journal of Dermatology, 50(4), 546-550, Apr. 2023, Refereed, Not invited
Corresponding - Analyzing the relationship between the efficacy of first-line immune checkpoint inhibitors and cumulative sun damage in Japanese patients with advanced BRAF wild-type nonacral cutaneous melanoma: A retrospective real-world, multicenter study.
Inozume T, Namikawa K, Kato H, Yoshikawa S, Kiniwa Y, Yoshino K, Mizuhashi S, Ito T, Takenouchi T, Matsushita S, Fujisawa Y, Matsuzawa T, Sugihara S, Asai J, Kitagawa H, Maekawa T, Isei T, Yasuda M, Yamazaki N, Uhara H, Nakamura Y.
J Dermatol Sci, 19(26), Apr. 2023 - Immune status and prognosis of stage II and III primary malignant melanoma: An analysis including 77 cases of acral lentiginous melanoma
Nakamura K, Ashida A, Kiniwa Y, Okuyama R.
The Journal of Dermatology, 50(4), e121-e122, Apr. 2023, Refereed - Systemic therapy for Asian patients with advanced BRAF V600-mutant melanoma in a real-world setting: A multi-center retrospective study in Japan (B-CHECK-RWD study).
Namikawa K, Ito T, Yoshikawa S, Yoshino K, Kiniwa Y, Ohe S, Isei T, Takenouchi T, Kato H, Mizuhashi S, Fukushima S, Yamamoto Y, Inozume T, Fujisawa Y, Yamasaki O, Nakamura Y, Asai J, Maekawa T, Funakoshi T, Matsushita S, Nakano E, Oashi K, Kato J, Uhara H, Miyagawa T, Uchi H, Hatta N, Tsutsui K, Maeda T, Matsuya T, Yanagisawa H, Muto I, Okumura M, Ogata D, Yamazaki N.
2023 - 乳房外パジェット病の発症病態とメカニズム
木庭幸子
皮膚科, 4(1), 9-11, 2023
Lead - Alopecia areata as an immune-related adverse event associated with response to immune checkpoint inhibitors
Rika Suzuki, Yukiko Kiniwa, Toshikazu Omodaka, Shiho Katsuie, Tatsuya Nihei, Ai Sato, Yuko Takazawa, Ryuhei Okuyama
EUROPEAN JOURNAL OF DERMATOLOGY, 32(4), 546-548, Jul. 2022, Refereed, Not invited
Corresponding - 特集 悪性黒色腫の最前線 分子標的治療の実際と今後の展開
木庭幸子
皮膚科, 2(1), 48-53, Jul. 2022
Lead - Toxic Epidermal Necrolysis Caused by Apalutamide: A Case Report of Treatment Using Etanercept with Conventional Steroid Therapy
Osawa, Kana; Kiniwa, Yukiko; Shimosato, Yuzuki; Midorikawa, Hirotaka; Shirai, Takushi; Sano, Tasuku; Nakamura, Kenta; Okuyama, Ryuhei;
ACTA DERMATO-VENEREOLOGICA, 102, adv00723, May 2022
- A Case of Apocrine Carcinoma Arising in a Sebaceous Naevus: Detection of HRAS G13R Mutation
KATSUIE, Shiho; KINIWA, Yukiko; MIKOSHIBA, Asuka; GOTO, Keisuke; OKUYAMA, Ryuhei;
ACTA DERMATO-VENEREOLOGICA, 102, adv00697, May 2022 - A Two-year-old Boy with a Depressed Area in the Groin Lipodystrophia centrifugalis abdominalis infantilis
Osawa, Kana; Kiniwa, Yukiko; Okuyama, Ryuhei;
ACTA DERMATO-VENEREOLOGICA, 102, adv00643, May 2022 - Prognoses of patients with melanoma who continue/discontinue anti-programmed death-1 therapy after achieving a complete response in a real-world setting: a multicentre retrospective study
Kato, Junji; Namikawa, Kenjiro; Uehara, Jiro; Nomura, Motoo; Nakamura, Yasuhiro; Uhara, Hisashi; Uchi, Hiroshi; Yoshikawa, Shusuke; Kiniwa, Yukiko; Nakamura, Yoshiyuki; Miyagawa, Takuya; Matsushita, Shigeto; Takenouchi, Tatsuya; Hatta, Naohito; Ohno, Fumitaka; Maeda, Taku; Fukushima, Satoshi; Yamazaki, Naoya;
BRITISH JOURNAL OF DERMATOLOGY, 2022 - Concordance in judgment of clinical borders of basal cell carcinomas in Japanese patients: A preliminary study of JCOG2005 (J-BASE-MARGIN)
Kamimura, Anna; Nakamura, Yasuhiro; Takenouchi, Tatsuya; Matsushita, Shigeto; Omodaka, Toshikazu; Yamamura, Kentaro; Uchi, Hiroshi; Yoshikawa, Shusuke; Yanagisawa, Hiroto; Ito, Takamichi; Kiyohara, Yoshio; Nakamura, Yoshio; Aoki, Megumi; Ishizuki, Shoichiro; Oashi, Kohei; Miyagawa, Takuya; Maeda, Taku; Ogata, Dai; Hatta, Naohito; Ohe, Shuichi; Isei, Taiki; Takahashi, Akira; Umeda, Yoshiyasu; Yamaguchi, Buntaro; Ishikawa, Masashi; Horimoto, Kohei; Fujsawa, Yasuhiro; Uehara, Jiro; Shibayama, Yoshitsugu; Kiniwa, Yukiko; Kawahara, Yu; Matsuya, Taisuke; Uhara, Hisashi; Kato, Junji; Nakamura, Yoshiyuki; Murakami, Takuo; Namikawa, Kenjiro; Yoshino, Koji; Funakoshi, Takeru; Takatsuka, Sumiko; Matsui, Yu; Sasaki, Jin; Koga, Hiroshi; Yokota, Kenji; Komori, Takaya; Fukushima, Satoshi; Yamazaki, Naoya;
JOURNAL OF DERMATOLOGY, 2022 - Prevalence of Psoriatic Arthritis in Nagano Prefecture, Japan, and Efficacy of the Psoriasis Epidemiology Screening Tool: A Real-World Survey
Meling, Maureen Tania; Ogawa, Eisaku; Sato, Yuki; Minagawa, Akane; Kiniwa, Yukiko; Okuyama, Ryuhei;
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 257(3), 205-210, 2022 - Case of bullous pemphigoid following coronavirus disease 2019 vaccination
Nakamura, Kenta; Kosano, Megumi; Sakai, Yuzuki; Saito, Nana; Takazawa, Yuko; Omodaka, Toshikazu; Kiniwa, Yukiko; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 48(12), E606-E607, Dec. 2021 - Real-world efficacy of anti-PD-1 antibody or combined anti-PD-1 plus anti-CTLA-4 antibodies, with or without radiotherapy, in advanced mucosal melanoma patients: A retrospective, multicenter study
Umeda, Yoshiyasu; Yoshikawa, Shusuke; Kiniwa, Yukiko; Maekawa, Takeo; Yamasaki, Osamu; Isei, Taiki; Matsushita, Shigeto; Nomura, Motoo; Nakai, Yasuo; Fukushima, Satoshi; Saito, Shintaro; Takenouchi, Tatsuya; Tanaka, Ryo; Kato, Hiroshi; Otsuka, Atsushi; Matsuya, Taisuke; Baba, Natsuki; Nagase, Kotaro; Inozume, Takashi; Onuma, Takehiro; Kuwatsuka, Yutaka; Fujimoto, Noriki; Kaneko, Takahide; Onishi, Masazumi; Namikawa, Kenjiro; Yamazaki, Naoya; Nakamura, Yasuhiro;
EUROPEAN JOURNAL OF CANCER, 157, 361-372, Nov. 2021 - TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment
Kawashima, Shusuke; Inozume, Takashi; Kawazu, Masahito; Ueno, Toshihide; Nagasaki, Joji; Tanji, Etsuko; Honobe, Akiko; Ohnuma, Takehiro; Kawamura, Tatsuyoshi; Umeda, Yoshiyasu; Nakamura, Yasuhiro; Kawasaki, Tomonori; Kiniwa, Yukiko; Yamasaki, Osamu; Fukushima, Satoshi; Ikehara, Yuzuru; Mano, Hiroyuki; Suzuki, Yutaka; Nishikawa, Hiroyoshi; Matsue, Hiroyuki; Togashi, Yosuke;
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 9(11), e003134, Nov. 2021 - Increased expression of secreted protein acidic and rich in cysteine and tissue inhibitor of metalloproteinase-3 in epidermotropic melanoma metastasis
Meling, Maureen Tania; Kiniwa, Yukiko; Ogawa, Eisaku; Sato, Yuki; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 48(11), 1772-1779, Nov. 2021 - 新・皮膚科セミナリウム：皮膚癌の発生メカニズムはどこまで明らかになったか！ 分子レベルでみたメラノーマの発症メカニズム
木庭幸子
日本皮膚科学会誌, 131(9), 2009-2016, Sep. 2021
Lead - Case of annular pustular psoriasis/circinate erythematous psoriasis induced by hydroxychloroquine in a patient with systemic lupus erythematosus: Possible association with CARD-14 mutation
Hirotaka Midorikawa, Yukiko Kiniwa, Akane Minagawa, Kana Osawa, Takushi Shirai, Tasuku Sano, Kenta Nakamura, Atsuko Ashida, Ken-Ichi Ueno, Takuya Takeichi, Masashi Akiyama, Ryuhei Okuyama
J Dermatol, 02 Jun. 2021 - 【皮膚悪性腫瘍（第２版）上-基礎と臨床の最新研究動向-】メラノーマ メラノーマの治療 免疫チェックポイント阻害薬 抗PD-1抗体薬．
木庭幸子
日本臨床, 79(増2), May 2021
Lead - 【皮膚悪性腫瘍（第２版）上-基礎と臨床の最新研究動向-】メラノーマメラノーマの治療 免疫チェックポイント阻害薬 新規免疫チェックポイント阻害薬 LAG-3抗体, TIM-3抗体, TIGIT抗体
木庭幸子
日本臨床, 79(増2), 407-413, May 2021
Lead - 【皮膚悪性腫瘍（第２版）上-基礎と臨床の最新研究動向-】メラノーマ メラノーマの分子病理学およびゲノミクス 分子生物学 メラノーマの循環腫瘍細胞
木庭幸子
日本臨床, 79(増2), 112-117, May 2021
Lead - アレルギー用語解説シリーズ 免疫チェックポイント阻害薬（解説）
木庭幸子，奥山隆平
アレルギー, 70(3), 224-225, May 2021
Lead - CCL5 production by fibroblasts through a local renin–angiotensin system in malignant melanoma affects tumor immune responses.
Nakamura K, Kiniwa Y, Okuyama R.
J Cancer Res Clin Oncol, 26 Mar. 2021 - Usefulness of monitoring circulating tumor cells as a therapeutic biomarker in melanoma with BRAF mutation
Kiniwa Y, Nakamura K, Mikoshiba A, Ashida A, Akiyama Y, Morimoto A, Okuyama R
BMC CANCER, 21(1), 287, 17 Mar. 2021 - Recent advances in molecular targeted therapy for unresectable and metastatic BRAF-mutated melanoma.
Kiniwa Y, Okuyama R
Jpn J Clin Oncol, 51(3), 315-20, Mar. 2021 - Ligand bound fatty acid binding protein 7 (FABP7) drives melanoma cell proliferation via modulation of Wnt/β-catenin signaling.
Umaru BA, Kagawa Y, Shil SK, Arakawa N, Pan Y, Miyazaki H, Kobayashi S, Yang S, Cheng A, Wang Y, Shinoda Y, Kiniwa Y, Okuyama R, Fukunaga K, Owada Y
Pharm Res, 38(3), 479-490, Mar. 2021 - Comparing the clinical efficacies of anti-PD-1 antibody monotherapy and anti-PD-1 and anti-CTLA-4 combination therapy as first-line immunotherapy in Japanese advanced acral melanoma: A retrospective, multicenter study (JAMP-neo study).
Nakamura, Yasuhiro; Kiniwa, Yukiko; Kato, Hiroshi; Yamasaki, Osamu; Maekawa, Takeo; Matsushita, Shigeto; Takenouchi, Tatsuya; Inozume, Takashi; Nakai, Yasuo; Fukushima, Satoshi; Saito, Shintaro; Otsuka, Atsushi; Fujimoto, Noriki; Isei, Taiki; Baba, Natsuki; Matsuya, Taisuke; Tanaka, Ryo; Kaneko, Takahide; Onishi, Masazumi; Yoshikawa, Shusuke;
JOURNAL OF CLINICAL ONCOLOGY, 39(15), 2021 - Case of bullous pemphigoid following coronavirus disease 2019 vaccination
Nakamura, Kenta; Kosano, Megumi; Sakai, Yuzuki; Saito, Nana; Takazawa, Yuko; Omodaka, Toshikazu; Kiniwa, Yukiko; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 2021
- Chemokine level predicts the therapeutic effect of anti-PD-1 antibody (nivolumab) therapy for malignant melanoma
Nakamura, Kenta; Ashida, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei;
ARCHIVES OF DERMATOLOGICAL RESEARCH, 2021 - Successful treatment of cutaneous infection due toPurpureocillium lilacinumusing voriconazole
Suzuki, Rika; Kiniwa, Yukiko; Shirai, Takushi; Takazawa, Yuko; Natori, Tatsuya; Mochizuki, Takashi; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 47(9), E342-E343, Sep. 2020 - Paraneoplastic pemphigus associated with Waldenstrom's macroglobulinemia
Shirai, Takushi; Kiniwa, Yukiko; Ishii, Norito; Hashimoto, Takashi; Senoo, Yasushi; Urushihata, Kazuhisa; Ashida, Atsuko; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 47(5), E200-E201, May 2020 - Detecting copy number alterations of oncogenes in cell-free DNA to monitor treatment response in acral and mucosal melanoma
Mikoshiba, Asuka; Ashida, Atsuko; Sakaizawa, Kaori; Kiniwa, Yukiko; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGICAL SCIENCE, 97(3), 172-178, Mar. 2020 - BRAF Mutation Heterogeneity in Melanoma Lesions
Sakaizawa, Kaori; Ashida, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei;
ACTA DERMATO-VENEREOLOGICA, 100(1), adv00045, Jan. 2020 - p63 overexpression in the epidermis of spiny keratoderma
Widyasaputra, Maureen Tania; Ogawa, Eisaku; Saiki, Minoru; Kiniwa, Yukiko; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 47(1), E29-E30, Jan. 2020 - Anti-PD1 checkpoint inhibitor therapy in acral melanoma: a multicenter study of 193 Japanese patients.
Nakamura Y, Namikawa K, Yoshino K, Yoshikawa S, Uchi H, Goto K, Nakamura Y, Fukushima S, Kiniwa Y, Takenouchi T, Uhara H, Kawai T, Hatta N, Funakoshi T, Teramoto Y, Otsuka A, Doi H, Ogata D, Matsushita S, Isei T, Hayashi T, Shibayama Y, Yamazaki N.
Ann Oncol, 31(9), 1198-1206, 2020 - 分子生物学からみたメラノーマの発症機序と新たな病型分類.
木庭幸子
MB Derma, 298, 11-18, 2020
Lead - Hemophagocytic syndrome associated with pembrolizumab therapy successfully controlled by cyclosporin
Sakai, Yuzuki; Nakamura, Kenta; Midorikawa, Hirotaka; Osawa, Kana; Shirai, Takushi; Sano, Tasuku; Kiniwa, Yukiko; Nakazawa, Hideyuki; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 2020 - Circulating Tumour DNA Reflects Tumour Burden Independently of Adverse Events Caused by Systemic Therapies for Melanoma
Ashida, Atsuko; Sakaizawa, Kaori; Mikoshiba, Asuka; Kiniwa, Yukiko; Okuyama, Ryuhei;
ACTA DERMATO-VENEREOLOGICA, 99(12), 1184-1185, Nov. 2019 - Thymoma-associated graft-versus-host-like disease treated with high-dose i.v. immunoglobulin
Sato, Yuki; Shirota, Shiho; Kiniwa, Yukiko; Sekiguchi, Nodoka; Okuyama, Ryuhei; Koizumi, Tomonobu;
JOURNAL OF DERMATOLOGY, 46(6), E224-E225, Jun. 2019 - Improvement of porphyria cutanea tarda following treatment of hepatitis C virus by direct-acting antivirals: A case report
Nihei, Tatsuya; Kiniwa, Yukiko; Mikoshiba, Yasutomo; Joshita, Satoru; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 46(5), E149-E151, May 2019 - Identification of genetic alterations in extramammary Paget disease using whole exome analysis
Kiniwa, Yukiko; Yasuda, Jun; Saito, Sakae; Saito, Rumiko; Motoike, Ikuko N.; Danjoh, Inaho; Kinoshita, Kengo; Fuse, Nobuo; Yamamoto, Masayuki; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGICAL SCIENCE, 94(1), 229-235, Apr. 2019 - Presence of antibodies to striated muscle and acetylcholine receptor in association with occurrence of myasthenia gravis with myositis and myocarditis in a patient with melanoma treated with an anti-programmed death 1 antibody
Shirai, T.; Kiniwa, Y.; Sato, R.; Sano, T.; Nakamura, K.; Mikoshiba, Y.; Ohashi, N.; Sekijima, Y.; Okuyama, R.;
EUROPEAN JOURNAL OF CANCER, 106, 193-195, Jan. 2019 - Real-world efficacy of anti-PD-1 antibodies in advanced acral melanoma patients: A retrospective, multicenter study (JAMP study).
Nakamura, Yasuhiro; Namikawa, Kenjiro; Yoshino, Koji; Yoshikawa, Shusuke; Uchi, Hiroshi; Goto, Katsunobu; Nakamura, Yoshiyuki; Fukushima, Satoshi; Kiniwa, Yukiko; Takenouchi, Tatsuya; Uhara, Hisashi; Kawai, Toru; Hatta, Naohito; Funakoshi, Takeru; Teramoto, Yukiko; Otsuka, Atsushi; Doi, Haruki; Ogata, Dai; Matsushita, Shigeto; Yamazaki, Naoya;
JOURNAL OF CLINICAL ONCOLOGY, 37(15), 2019 - Sarcoidosis mimicking malar rash: a case of lupus pernio
Sato, Rika; Kiniwa, Yukiko; Shirai, Takushi; Okuyama, Ryuhei;
EUROPEAN JOURNAL OF DERMATOLOGY, 29(3), 331-332, 2019 - Type 1 diabetes in a melanoma patient treated with ipilimumab after nivolumab
Omodaka, Toshikazu; Kiniwa, Yukiko; Sato, Yuki; Suwa, Manabu; Sato, Misato; Yamaguchi, Tomohiko; Sato, Ai; Miyake, Tomomi; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 45(10), E289-e290, Oct. 2018 - Diversity of circulating tumor cells in peripheral blood: Detection of heterogeneous BRAF mutations in a patient with advanced melanoma by single-cell analysis
Kiniwa, Yukiko; Nakamura, Kenta; Mikoshiba, Asuka; Akiyama, Yasuyuki; Morimoto, Atsushi; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGICAL SCIENCE, 90(2), 211-213, May 2018 - Involvement of local renin-angiotensin system in immunosuppression of tumor microenvironment
Nakamura, Kenta; Yaguchi, Tomonori; Ohmura, Gaku; Kobayashi, Asuka; Kawamura, Naoshi; Iwata, Takashi; Kiniwa, Yukiko; Okuyama, Ryuhei; Kawakami, Yutaka;
CANCER SCIENCE, 109(1), 54-64, Jan. 2018 - Expression of Mucin 1 in Mycosis Fungoides Tumour Cells: A Case Report
Shirai, Takushi; Kiniwa, Yukiko; Asaka, Shiho; Shimojo, Yasuyo; Kamijo, Fuminao; Okuyama, Ryuhei;
ACTA DERMATO-VENEREOLOGICA, 97(6), 747-748, Jun. 2017 - Hypohidrotic ectodermal dysplasia: A report of two cases
Miyake, Tomomi; Kiniwa, Yukiko; Kosho, Tomoki; Nakano, Hajime; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 44(4), 479-481, Apr. 2017 - Polyarteritis nodosa in a patient with haemophilia A
Tsuji, Asuka; Kiniwa, Yukiko; Kamijo, Fuminao; Miyake, Tomomi; Ohashi, Atsuko; Senoo, Noriko; Urushihata, Kazuhisa; Okuyama, Ryuhei;
EUROPEAN JOURNAL OF DERMATOLOGY, 27(2), 203-204, Mar. 2017 - Cutaneous plasmacytosis associated with autoimmune hemolytic anemia
Kiniwa, Yukiko; Matoba, Hisanori; Hamano, Hideaki; Senoo, Yasushi; Okuyama, Ryuhei;
JOURNAL OF DERMATOLOGY, 43(3), 343-345, Mar. 2016 - Intratumoral expression levels of PD-L1, GZMA, and HLA-A along with oligoclonal T cell expansion associate with response to nivolumab in metastatic melanoma
Inoue, Hiroyuki; Park, Jae-Hyun; Kiyotani, Kazuma; Zewde, Makda; Miyashita, Azusa; Jinnin, Masatoshi; Kiniwa, Yukiko; Okuyama, Ryuhei; Tanaka, Ryota; Fujisawa, Yasuhiro; Kato, Hiroshi; Morita, Akimichi; Asai, Jun; Katoh, Norito; Yokota, Kenji; Akiyama, Masashi; Ihn, Hironobu; Fukushima, Satoshi; Nakamura, Yusuke;
ONCOIMMUNOLOGY, 5(9), 2016 - A case of Kindler syndrome with severe esophageal stenosis
Ohashi, Atsuko; Kiniwa, Yukiko; Okuyama, Ryuhei; Kosho, Tomoki; Suga, Tomoaki; Has, Cristina; Kubo, Hitomi;
INTERNATIONAL JOURNAL OF DERMATOLOGY, 54(4), E106-E108, Apr. 2015 - A nonsense nucleotide substitution in the oculocutaneous albinism II gene underlies the original pink-eyed dilution allele (Oca2p) in mice. Exp Anim.
Shoji H, Kiniwa Y, Okuyama R, Yang M, Higuchi K, Mori M.
Exp Anim., Epub ahead of print, Epub ahead of print, 22 Jan. 2015, Refereed - Identification of DRG-1 As a Melanoma-Associated Antigen Recognized by CD4(+) Th1 Cells
Kiniwa, Yukiko; Li, Jiang; Wang, Mingjun; Sun, Chuang; Lee, Jeffrey E.; Wang, Rong-Fu; Wang, Helen Y.;
PLOS ONE, 10(5), 2015 - 5-Hydroxymethylcytosine as a useful marker to differentiate between malignant melanomas and benign melanocytic nevi.
Uchiyama R,Uhara H, Uchiyama A, Ogawa E, Takazawa Y, Ashida A, Koga H, Hayashi K, Kiniwa Y, Okuyama R
J Dermatol Sci., 73(2), 161-3, 01 Feb. 2014, Refereed - Toll-like receptor 4 signaling promotes the migration of human melanoma cells.
Takazawa Y, Kiniwa Y, Ogawa E, Uchiyama A, Ashida A, Uhara H, Goto Y, Okuyama R.
Tohoku J Exp Med, 234, 57-65, 2014 - Generalized pustulosis associated with disseminated Mycobacterium avium infection in a non-AIDS patient.
Asai Y, Kiniwa Y, Okada N, Futatsugi T, Ushiki A, Uhara H, Okuyama R.
Eur J Dermatol., 24(3), 402-3, 2014 - IgA/IgG Pemphigus with Infiltration of Neutrophils and Eosinophils in an Ulcerative Colitis Patient.
Uchiyama R, Ishii N, Arakura F, Kiniwa Y, Nakazawa K, Uhara H, Hashimoto T, Okuyama R.
Acta Derm Venereol, 94, in press, 2014 - 悪性黒色腫の治療（９）免疫療法 ２）ワクチン療法
木庭幸子
日本臨床, 71(増4), 378-382, Aug. 2013 - 悪性黒色腫の治療（１０）分子標的薬 ３）抗体療法
木庭幸子
日本臨床,, 71(増4), 397-401, Aug. 2013 - 悪性黒色腫の浸潤・転移（２）浸潤・転移に関連する非免疫機序
木庭幸子
日本臨床, 71(増4), 171-175, Aug. 2013 - NRAS mutations in primary and metastatic melanomas of Japanese patients.
Uhara H, Ashida A, Koga H, Ogawa E, Uchiyama A, Uchiyama R, Hayashi K, Kiniwa Y, Okuyama R.,
Int J Clin Oncol, ., ., 06 Jun. 2013 - Low p53 positivity in verrucous skin lesion in diabetic neuropathy occurring on the dorsum of the foot.
Ashida A, Kiniwa Y, Kobayashi A, Okuyama R
Int J Dermatol, 52(3), 378-80, Mar. 2013 - 悪性黒色腫の抗体治療
木庭幸子、奥山隆平
日本臨床, 70(12), 2172-76, 01 Dec. 2012 - 非腫瘍性疾患の分子標的薬 アトピー性皮膚炎
木庭幸子、奥山隆平
日本臨床, 70(増刊号), 555-60, 20 Nov. 2012 - Assessment of BRAF and KIT mutations
Atsuko Ashida, Hisashi Uhara, Yukiko Kiniwa, Misae Oguchi, Hiroshi Murata, Yasufumi Goto, Aya Uchiyama, Eisaku Ogawa, Koichi Hayashi, Hiroshi Koga, Ryuhei Okuyama
J Dermatological Science, 66, 240-242, 01 Apr. 2012 - Mutation analysis of BRAF and KIT in circulating melanoma cells at the single cell level
Sakaizawa K, Goto Y, Kiniwa Y, Uchiyama A, Harada K, Shimada S, Saida T, Ferrone S, Takata M, Uhara H, Okuyama R.
British J Cancer, 106, 939-46, 01 Feb. 2012 - A case of epidermolysis bullosa acquisitaassociated with laryngeal stenosis.
Kiniwa Y, Ashida A, Ohashi A, Kitoh R, Fukuda S, Hashimoto T, Okuyama R.
Acta Derm Venereol, 92, 93-94, 15 Jan. 2012 - A case of angiosarcoma arising on a closed shunt in a patient with chronic renal failure.
Kamijo F, Kiniwa Y, Goto Y, Tanaka A, Kobayashi A, Shirota S, Fukuzawa M, Saida S
J Am Acad Dermatol, 65(4), 882-883, Apr. 2011 - Thermal Angioedema Induced by Hot Water
Kobayashi A, Uhara H, Ashida A, Kiniwa Y, Okuyama R
Acta Derm Veneneol, 91(3), 343-344, Mar. 2011 - A case of systemic anaplastic large cell lymphoma with “Hodgkin-like” appearance and skin involvement mimicking lymphomatoid papulosis.
Kiniwa Y, Ide Y, Fukushima M,Asano N, Saida T
J Cutan Pathol,, 8(1), 38-42, 2011 - NADPH oxidase 4 contributes to transformation phenotype of melanoma cells by regulating G2-M cell cycle progression
YamauraM, MitsushitaJ, Furuta, S, Kiniwa Y,Ashida A, Goto Y, Shang W. H, Kubodera M, Kato M, Takata M, Saida T,Kamata T,
Cancer Res, 69(6), 2647-54, 2009 - Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway.
Peng G, Wang HY, Peng W, Kiniwa Y , Seo KH , Wang RF
Immunity, 27(2), 334-348, 2007 - CD8+ Foxp3+ regulatory T cells mediate immune suppression in prostate cancer
Kiniwa Y, Wang HY, Peng W, Peng G, Wheeler T, Thompson T, Wang RF
Clin Cancer Res, 13(23), 6947-58, 2007 - Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function.
Peng G, Guo Z, Kiniwa Y, Voo KS, Peng W, Fu T, Wang DY, Li Y, Wang HY, Wang RF
Science., 309, 1380-1384, 2005 - Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy
Wang HY, Lee DA, Peng G, Guo Z, Li Y, Kiniwa Y, Shevach EM, Wang RF
Immunity, 20(1), 107-118, 2004 - Identification of bladder cancer antigens recognized by IgG antibodies of a patient with metastatic bladder cancer
Ito K, Fujita T, Akada M, Kiniwa Y, Tsukamoto M, Yamamoto A, Matsuzaki Y, Matsushita M, Asano T, Nakashima J, Tachibana M, Hayakawa M, Ikeda H, Murai M, Kawakami Y
Int J Cancer, 108(5), 712-724, 2004 - Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma
Kiniwa, Y; Fujita, T; Akada, M; Ito, K; Shofuda, T; Suzuki, Y; Yamamoto, A; Saida, T; Kawakami, Y
CANCER RESEARCH, 61(21), 7900-7907, 2001
Books and other publications
- 今日の治療指針2024版―私はこう治療している【褥瘡】
木庭幸子
福井 次矢 / 高木 誠 / 小室 一成・医学書院, Jan. 2024
ISBN:978-4-260-05343-3「褥瘡」 『今日の治療指針2020』
木庭幸子, Joint work
医学書院, 1326-7 01 Jan. 2020
ISBN:978-4-260-03939-0１冊でわかる皮膚がん
木庭幸子, Joint work, 悪性黒色腫の免疫療法
文光堂（斎田俊明、宮地良樹、清水宏、編）, 07 Feb. 2011Research Themes
- 循環腫瘍細胞を用いたメラノーマに対するプレシジョン医療の開発
科学研究費補助金, 科研費 基盤研究(C)
2020 - 2022 - AMED次世代がん医療創生研究事業
2016 - 2019 - 悪性黒色腫の循環腫瘍細胞を用いた個別化医療の開発と耐性機序の解明
科学研究費補助金, 基盤C一般
2016 - 2018 - Notchシグナルがメラノーマで果たす役割の解明と治療への応用
科学研究費補助金, 基盤研究(C)
2013 - 2015 - メラノーマにおける制御性T細胞誘導へのケモカインと腫瘍浸潤マクロファージの関与
科学研究費補助金, 基盤研究(C)
2009 - 2012 - 創薬化を目指したglypican-3由来がんペプチドワクチン療法のエビデンス創出のための臨床試験エビデンス創出のための臨床試験創薬化を目指したglypican-3由来がんペプチドワクチン療法のエビデンス創出のための臨床試験創薬化を目指したglypican-3由来がんペプチドワクチン療法のエビデンス創出のための臨床試験
科学研究費補助金, 厚生労働科学研究費補助金
2008 - 2011 - ヒトメラノーマにおける腫瘍拒絶能と制御性Ｔ細胞による腫瘍エスケープ機構の解明
科学研究費補助金, 基盤研究(C)
2007 - 2008 - メラノーマにおける抗原特異的な制御性リンパ球の解析
2009 - ヒトメラノーマにおける癌幹細胞の同定
2008 - 悪性黒色腫における癌幹細胞の同定
2007 - development of precision medicine for melanoma
- circulating tumor cells in melanoma
- Identification of genomic alterations in extramammary Paget disease using whole exome sequencing
