ITO KEN-ICHI
Academic Assembly School of Medicine and Health Sciences Institute of Medicine
School of Medicine Department of Surgery Division of Breast and Endocrine Surgery
Professor
Researcher Information
Research activity information
Paper
- Changes in the pathophysiology of primary hyperparathyroidism and analysis of postoperative recurrence cases at a regional core hospital in Japan: experience of 35 years in Shinshu University Hospital.
Kanai T, Oba T, Morikawa H, Amitani M, Chino T, Shimizu T, Ono MT, Maeno K, Ito KI, Ito T.
Ann Palliat Med., 2023
- Significance of skeletal muscle index-to-body mass index ratio as a predictor of postsurgical bleeding after mastectomy in patients with breast cancer.
6. Morikawa H, Oba T, Kiyosawa N, Iji R, Amitani M, Chino T, Shimizu T, Ono M, Kanai T, Maeno K, Ito KI.
Breast Cancer., 2023 - Development of a predictive score for post-hemithyroidectomy hypothyroidism using skeletal muscle index, remnant thyroid index, and thyroid-stimulating hormone levels: a retrospective cohort study.
5. Amitani M, Oba T, Kiyosawa N, Iji R, Morikawa H, Chino T, Shimizu T, Ono M, Kanai T, Maeno K, Ito KI.
Quant Imaging Med Surg, 2023 - Eribulin promotes proliferation of CD8+ T cells and potentiates T cell-mediated anti-tumor activity against triple-negative breast cancer cells.
Shimizu T, Oba T, Oshi M, Ito KI.
Breast Cancer Res Treat., 2023 - The Advantage of Using an Optical See-Through Head-Mounted Display in Ultrasonography-Guided Needle Biopsy Procedures: A Prospective Randomized Study.
Shimizu T, Oba T, Ito KI.
J Clin Med, 2023 - Clinical and immunological relevance of SLAMF6 expression in the tumor microenvironment of breast cancer and melanoma.
Oba T, Long M, Ito KI, Ito F.
Sci Rep, 2023 - 甲状腺未分化癌治療における最近の進歩
伊藤研一、森川大樹、網谷正統、清水忠史、大場崇旦、伊藤勅子、金井敏晴
日本外科学会誌, 2023 - 人生100年時代の外科医療
2. 伊藤研一、山本雄造
日本臨床外科学会誌, 2023 - A Case of a Cystic Parathyroid Adenoma with Marked Hyperparathyroidism but Difficult Preoperative Diagnostic Imaging
KUBOTA Satoshi, SHIMADA Yasuho, TAKAYAMA Shohei, OBA Takaaki, ITO Ken-ichi, KOMATSU Mitsuhisa
The Shinshu Medical Journal, 70(3), 189-194, Jun. 2022 - Surgical resection of the primary tumor prevents an undesirable locoregional condition and improves the quality of life in patients with anaplastic thyroid cancer.
Kanai T, Ito T, Morikawa H, Amitani M, Shimizu T, Ohno K, Ono M, Oba T, Maeno K, Ito KI
Surg Today, 2022 - Epidermal growth factor receptor activation confers resistance to lenvatinib in thyroid cancer cells.
Ohno K, Shibata T, Ito KI.
Cancer Science., 2022 - Neutrophil-to-Lymphocyte Ratio Is Associated With the Proportion of Poorly Differentiated Components in Papillary Thyroid Carcinoma.
Oba T, Kazuma M, Kiyosawa N, Morikawa H, Amitani M, Chino T, Shimizu T, Ono M, Ito T, Kanai T, Ito KI.
J Surg Res., 2022 - Hypercalcemic crisis caused by primary hyperparathyroidism in a 11-year-old boy: a rare case report and review of the literature
Hayashi S, Oba T, Ichikawa K, Nakamura C, Hara Y, Kanai T, Sato Y, Uehara T, Ito KI.
Gland Surgery, 2022 - Skeletal muscle loss during neoadjuvant chemotherapy predicts poor prognosis in patients with breast cancer.
Amitani M, Oba T, Kiyosawa N, Morikawa H, Chino T, Soma A, Shimizu T, Ohno K, Ono M, Ito T, Kanai T, Maeno K, Ito KI.
BMC CANCER, 2022 - The mechanisms involved in the resistance of estrogen receptor-positive breast cancer cells to palbociclib are multiple and change over time
Ono, Mayu; Oba, Takaaki; Shibata, Tomohiro; Ito, Ken-Ichi;
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 147(11), 3211-3224, Nov. 2021
- HDAC6 inhibition enhances the anti-tumor effect of eribulin through tubulin acetylation in triple-negative breast cancer cells
Oba, Takaaki; Ono, Mayu; Matoba, Hisanori; Uehara, Takeshi; Hasegawa, Yoshie; Ito, Ken-ichi;
Breast Cancer Research and Treatment, 186(1), 37-51, Feb. 2021 - Concomitant use of F-18-FDG PET-CT SUVmax is useful in the assessment of Ki67 labeling index in core-needle biopsy specimens of breast cancer
Nakajima, Hiroki; Maeno, Kazuma; Ito, Tokiko; Kanai, Toshiharu; Oba, Takaaki; Ono, Mayu; Takayama, Fumiyoshi; Uehara, Tsuyoshi; Ito, Ken-ichi;
Gland Surgery, 10(1), 1-9, Jan. 2021 - Prognostic Nutritional Index Is Superior to Neutrophil-to-lymphocyte Ratio as a Prognostic Marker in Metastatic Breast Cancer Patients Treated With Eribulin
Oba, Takaaki; Maeno, Kazuma; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
Anticancer Research, 41(1), 445-452, Jan. 2021 - Tamoxifen resistance alters sensitivity to 5-fluorouracil in a subset of estrogen receptor-positive breast cancer
Watanabe, Takayuki; Oba, Takaaki; Tanimoto, Keiji; Shibata, Tomohiro; Kamijo, Shinobu; Ito, Ken-ichi;
PLOS ONE, 16(6), e0252822, 2021 - Surgical treatment for mediastinal lymph node metastasis of thyroid cancer
Kanai Toshiharu;Amitani Masatugu;Shimizu Tadafumi;Ohno Koichi;Ono Mayu;Oba Takaaki;Ito Tokiko;Maeno Kazuma;Ito Ken-ichi
Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery, 38(2), 63-67, 2021 - Bone morphogenetic protein-7 expression reflects the high proliferative ability and aggressiveness of thymic epithelial tumors
Miura, Kentaro; Hamanaka, Kazutoshi; Uehara, Tsuyoshi; Momose, Masanobu; Kanai, Yukiko; Matsuoka, Shunichiro; Takeda, Tetsu; Agatsuma, Hiroyuki; Hyogotani, Akira; Ito, Ken-ichi;
JOURNAL OF THORACIC DISEASE, 12(3), 448-456, Mar. 2020 - Neoadjuvant chemotherapy-induced decrease of prognostic nutrition index predicts poor prognosis in patients with breast cancer
Oba, Takaaki; Maeno, Kazuma; Takekoshi, Daiya; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Ito, Ken-ichi;
BMC CANCER, 20(1), 2020 - Comparative efficacy and safety of tyrosine kinase inhibitors for thyroid cancer: a systematic review and meta-analysis
Oba, Takaaki; Chino, Tatsunori; Soma, Ai; Shimizu, Tadafumi; Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi;
Endocrine journal, 67(12), 1215-1226, 2020 - 癌微小環境研究up-date(第5回)癌微小環境に基づいた乳癌治療
伊藤 研一
Cancer board of the breast = キャンサーボードオブザブレスト, 5(2), 102-104, Sep. 2019 - A Case of Hereditary Breast and Ovarian Cancer Syndrome with Serous Tubal Intraepithelial Lesions in Bilateral Fimbriae Resected by Laparoscopic Risk-reducing Salpingo-oophorectomy
KASHIMA Hiroyasu, OKA Kenji, SHINAGAWA Manaka, YAMANAKA Sakura, ONO Motoki, TAKEUCHI Hodaka, IDA Koichi, HIGUCHI Shotaro, YAMADA Yasushi, KOBARA Hisanori, KIKUCHI Norihiko, MIYAMOTO Tsutomu, TACHIBANA Ryota, FUKUSHIMA Yoshimitsu, KOSHO Tomoki, IESATO Asumi, ITO Ken-ichi, ASAKA Shiho, UEHARA Takeshi, SHIOZAWA Tanri
The Shinshu Medical Journal, 67(3), 209-215, Jun. 2019
- FGF2-FGFR1 pathway activation together with thymidylate synthase upregulation is induced in pemetrexed-resistant lung cancer cells
Miura K, Oba T, Hamanaka K, Ito K
Oncotarget, 10, 1171-1192, 2019 - 甲状腺乳頭癌の再発リスク分類
金井敏晴、伊藤研一、千野辰徳、小野真由、大野晃一、伊藤勅子、前野一真
日本内分泌外科学会雑誌, 36(4), 209-212, 2019 - Clinical features and long-term results of poorly differentiated carcinoma of thyroid ~single-center analysis
Maeno Kazuma;Ito Ken-ichi;Shimizu Tadafumi;Soma Ai;Takekoshi Daiya;Ono Mayu;Oba Takaaki;Ito Tokiko;Kanai Toshiharu;Uehara Takeshi
Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery, 36(4), 235-239, 2019 - Lenvatinib (VEGFR inhibitor) : Results of clinical trials and its proper use
伊藤 研一;清水 忠史;相馬 藍;竹腰 大也;小野 真由;大場 崇旦;伊藤 勅子;金井 敏晴;前野 一真
腫瘍内科 = Clinical oncology, 22(4), 404-409, Oct. 2018 - A Retrospective Study of the Efficacy of Perioperative Oral Management on Prevention of Postoperative Pneumonia Associated with Lung Cancer Surgery
KAJIHARA Ryo, YAMADA Shin-ichi, NISHIMAKI Fumihiro, KONDO Eiji, KAMATA Takahiro, KOYAMA Tsutomu, MATSUOKA Shunichiro, TAKEDA Tetsu, MIURA Kentaro, YAMADA Kyoko, HAMANAKA Kazutoshi, ITO Ken-ichi, KURITA Hiroshi
The Shinshu Medical Journal, 66(4), 249-256, Aug. 2018 - Small molecule inhibitor : Lenvatinib
伊藤 勅子;伊藤 研一
腫瘍内科 = Clinical oncology, 21(6), 675-682, Jun. 2018 - Combination of two anti-tubulin agents, eribulin and paclitaxel, enhances anti-tumor effects on triple-negative breast cancer through mesenchymal-epithelial transition.
Oba T, Ito KI.
Oncotarget, 9(33), 22986-23002, May 2018 - Increased Expression of Y-Box-Binding Protein-1 in Hind-Limb Muscles During Regeneration from Ischemic Injury in Mice
Fuke, Megumi; Narita, Makoto; Wada, Yuko; Seto, Tatsuichiro; Okada, Kenji; Nakayama, Jun; Izumi, Hiroto; Ito, Ken-ichi;
TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 244(1), 53-62, Jan. 2018 - Analysis of surgical treatment of Masaoka stage III-IV thymic epithelial tumors.
Hamanaka K, Koyama T, Matsuoka S, Takeda T, Miura K, Yamada K, Hyogotani A, Seto T, Okada K, Ito KI.
Gen Thorac Cardiovasc Surg, in press, 2018 - A case of mixed type squamous cell carcinoma of the breast with enlarged squamous component during neoadjuvant chemotherapy
Kanai Toshiharu;Oba Takaaki;Ito Tokiko;Maeno Kazuma;Ito Ken-ichi;Tamada Hisashi
Official Journal of the Japan Association of Endocrine Surgeons and the Japanese Society of Thyroid Surgery, 35(4), 282-287, 2018 - A Case of Juvenile Fibroadenoma of the Breast Enlarging Rapidly Soon after Menarche in a 14-year-old Girl
IKEHARA Tomohiko;OBA Takaaki;MAENO Kazuma;ITO Ken-ichi;KOBAYASHI Sho;UEHARA Takeshi
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association), 79(6), 1187-1192, 2018 - Chylous leakage after axillary lymph node dissection in a patient with breast cancer
Oba, Takaaki; Ono, Mayu; Iesato, Asumi; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi;
BREAST JOURNAL, 24(3), 438-440, 2018 - A Case of Adenomyoepithelioma of the Breast Showing Strong Uptake of (18) F-Fluorodeoxyglucose on a Positron Emission Tomography.
Oba T, Maeno K, Ono M, Iesato A, Ito T, Kanai T, Mochizuki Y, Ito KI, Yoshizawa A, Takayama F.
Breast J, 23(2), 220-224, Mar. 2017 - Case of painless thyroiditis that developed during adjuvant chemotherapy for breast cancer.
Iesato A, Oba T, Ono K, Watanabe T, Ito T, Kanai T, Maeno K, Ito K.
Int Cancer Conf J, 6(4), 184-187, 2017 - PATZ1 knockdown enhances malignant phenotype in thyroid epithelial follicular cells and thyroid cancer cells
Iesato, Asumi; Nakamura, Teruo; Izumi, Hiroto; Uehara, Takeshi; Ito, Ken-Ichi;
Oncotarget, 8(47), 82754-82772, 2017 - Human 3 beta-hydroxysteroid dehydrogenase type 1 in human breast cancer: clinical significance and prognostic associations
Hanamura, Toru; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Shimojo, Yasuyo; Uehara, Takeshi; Suzuki, Takashi; Hayashi, Shin-ichi; Ito, Ken-ichi;
CANCER MEDICINE, 5(7), 1405-1415, Jul. 2016 - 女性のがん患者の生活・生命の質（QOL）の実態調査 : 術後1年間のQOL調査結果から
増樺京子, 竹内沙弥香, 所真由美, 執印抄枝子, 青柳美恵子, 伊藤勅子, 伊藤研一, 樋口正太郎, 塩沢丹里
信州大学医学部附属病院看護研究集録, 45(1), 1-6, Mar. 2016 - Significance of sentinel lymph nodes with low gamma counts in breast cancer patients via radioisotopic sentinel lymph node biopsy
Maeno K, Ito T, Koyama H, Kanai T, Mochizuki Y, Ito K
Arch Surg Oncol, 2, 1, 2016 - ABCB1 and ABCC11 confer resistance to eribulin in breast cancer cell lines
Oba, Takaaki; Izumi, Hiroto; Ito, Ken-ichi;
Oncotarget, 7(43), 70011-70027, 2016 - Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review
Oba, Takaaki; Ono, Mayu; Iesato, Asumi; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ito, Ken-ichi; Tateishi, Ayako; Yoshizawa, Akihiko; Takayama, Fumiyoshi;
OncoTargets and Therapy, 9, 1641-1646, 2016 - Breast metastases of gastric signet-ring cell carcinoma: a report of two cases and review of the literature
Iesato, Asumi; Oba, Takaaki; Ono, Mayu; Hanamura, Toru; Watanabe, Takayuki; Ito, Tokiko; Kanai, Toshiharu; Maeno, Kazuma; Ishizaka, Katsuhiko; Kitabatake, Hiroyuki; Takeuchi, Daisuke; Suzuki, Akira; Nakayama, Jun; Ito, Ken-ichi;
OncoTargets and Therapy, 8, 91-97, 2015 - Coexpression of EpCAM, CD44 Variant Isoforms and Claudin-7 in Anaplastic Thyroid Carcinoma
Okada, Toshihiro; Nakamura, Teruo; Watanabe, Takayuki; Onoda, Naoyoshi; Ashida, Atsuko; Okuyama, Ryuhei; Ito, Ken-ichi;
PLOS ONE, 9(4), e94487, 2014 - Expression of Polypeptide N-Acetylgalactosaminyl Transferase-3 and Its Association with Clinicopathological Factors in Thyroid Carcinomas
Mochizuki, Yasuhiro; Ito, Ken-ichi; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun;
THYROID, 23(12), 1553-1560, 2013 - Rapid tumor necrosis and massive hemorrhage induced by bevacizumab and paclitaxel combination therapy in a case of advanced breast cancer
Ono, Mayu; Ito, Tokiko; Kanai, Toshiharu; Murayama, Koichi; Koyama, Hiroshi; Maeno, Kazuma; Mochizuki, Yasuhiro; Iesato, Asumi; Hanamura, Toru; Okada, Toshihiro; Watanabe, Takayuki; Ito, Ken-ichi;
OncoTargets and Therapy, 6, 1393-1398, 2013 - Association of Nuclear YB-1 Localization With Lung Resistance-related Protein and Epidermal Growth Factor Receptor Expression in Lung Cancer
Hyogotani, Akira; Ito, Ken-ichi; Yoshida, Kazuo; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun;
CLINICAL LUNG CANCER, 13(5), 375-384, Sep. 2012 - Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer
Ito, Tokiko; Kamijo, Shinobu; Izumi, Hiroto; Kohno, Kimitoshi; Amano, Jun; Ito, Ken-ichi;
Breast Cancer Research and Treatment, 133(1), 145-159, May 2012 - Multimodality therapeutic outcomes In anaplastic thyroid carcinoma: Improved survival in subgroups of patients with localized primary tumors
Ito, Ken-ichi; Hanamura, Toru; Murayama, Koichi; Okada, Toshihiro; Watanabe, Takayuki; Harada, Michihiko; Ito, Tokiko; Koyama, Hiroshi; Kanai, Toshiharu; Maeno, Kazuma; Mochizuki, Yasuhiro; Amano, Jun;
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 34(2), 230-237, Feb. 2012 - Full-thickness chest-wall resection followed by thorax reconstruction for recurrent malignant phyllodes tumor
Ito, Tokiko; Ito, Ken-ichi; Okada, Toshihiro; Murayama, Koichi; Hanamura, Toru; Kanai, Toshiharu; Maeno, Kazuma; Mochizuki, Yasuhiro; Kondo, Ryoichi; Amano, Jun; Osada, Yoshiro; Asano, Koji;
International journal of clinical oncology, 16(2), 156-160, Apr. 2011 - Upregulation of the apoptosis-related inflammasome in cardiac allograft rejection
Seto, Tatsuichiro; Kamijo, Shinobu; Wada, Yuko; Yamaura, Kazuhiro; Takahashi, Kohei; Komatsu, Kazunori; Otsu, Yoshinori; Terasaki, Takamitsu; Fukui, Daisuke; Amano, Jun; Taniguchi, Shun'ichiro; Sagara, Junji; Ito, Ken-ichi;
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 29(3), 352-359, Mar. 2010 - ENDOSCOPIC-ASSISTED SKIN-SPARING MASTECTOMY COMBINED WITH SENTINEL NODE BIOPSY
Ito, Ken-Ichi; Kanai, Toshiharu; Gomi, Kuniyuki; Watanabe, Takayuki; Ito, Tokiko; Komatsu, Akira; Fujita, Tomoyuki; Amano, Jun;
ANZ JOURNAL OF SURGERY, 78(10), 894-898, Oct. 2008 - Hepatocyte growth factor prevents pulmonary ischernia-reperfusion injury in mice
Makiuchi, Akiko; Yamaura, Kazuhiro; Mizuno, Shinya; Matsumoto, Kunio; Nakamura, Toshikazu; Amano, Jun; Ito, Ken-ichi;
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 26(9), 935-943, Sep. 2007 - Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo
Ohtsu Y, Johkura K, Ito K, Akashima T, Asanuma K, Ogiwara N, Oka T, Komuro I, Sasaki K, Amano J
CURRENT MEDICAL RESEARCH AND OPINION, 21(5), 795-803, 2005 - Increased nuclear localization of transcription factor Y-box binding protein 1 accompanied by up-regulation of P-glycoprotein in breast cancer pretreated with paclitaxel
Fujita T, Ito K, Izumi H, Kimura M, Sano M, Nakagomi H, Maeno K, Hama Y, Shingu K, Tsuchiya S, Kohno K, Fujimori M
CLINICAL CANCER RESEARCH, 11(24), 8837-8844, 2005 - Suppression of acute and chronic rejection by hepatocyte growth factor in a murine model of cardiac transplantation - Induction of tolerance and prevention of cardiac allograft vasculopathy
Yamaura, K; Ito, K; Tsukioka, K; Wada, Y; Makiuchi, A; Sakaguchi, M; Akashima, T; Fujimori, M; Sawa, Y; Morishita, R; Matsumoto, K; Nakamura, T; Suzuki, J; Amano, J; Isobe, M
Circulation, 110(12), 1650-1657, 2004 - Mutation of proline residues in the NH2-terminal region of the multidrug resistance protein, MRP1(ABCC1): effects on protein expression, membrane localization, and transport function.
Ito K, Weigl LE, Deeley RG, Cole SPC.
Biochim Biophys Acta-Biomember1615, 103-114, 2003 - Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer
Maeno K, Ito K, Hama Y, Shingu K, Kimura M, Sano M, Nakagomi H, Tsuchiya S, Fujimori M
Cancer Letters, 198(1), 89-97, 2003 - Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport
K. Ito/ S. Cole
J. Biol. Chem, 276, 15616-15624, 2001 - Mutation of Trp1254 in the multispecific organic anion transporter, MRP2 (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity
Ito K, Oleschuk CJ, Westlake C, Vasa MZ, Deeley RG, Cole SPC
J. Biol. Chem, 276, 38108-38114, 2001 - Clinical significance of the increased multidrug resistance-associated protein (MRP) gene expression in patients with primary breast cancer
K. Ito/ M. Fujimori/ J. Amano
Oncol Res, 10, 99-109, 1998 - Expression of tissue-type plasminogen activator and its inhibitor couples with development of capillary network by human microvascular endothelial cells on Matrigel
Ito K, Ryuto M, Ushiro S, Ono M, Sugenoya A, Kuraoka A, Shibata Y, Kuwano M
J. Cell. Physiol, 162, 213-024, 1995 - anti-angiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvasucular endothelial cells and neovascularization in mice.
Ito k, Abe T, Tomita M, Morimoto A, Kohno K, Mori T, Ono M, Sugenoya A, Nishihira T, Kuwano M.
Int J Cancer, 55(4), 660-666, 1993
