MURAKAMI Aito
Institute for Aqua Regeneration
Assistant Professor
Researcher Information
Career
Educational Background
- 2023 - 2025, Shinshu University, Graduate School of Medicine, Science and Technology, Department of Science and Technology
- 2020 - 2022, Shinshu University, Graduate School of Science and Technology, Department of Agriculture
- 2015 - 2020, Shinshu University, Faculty of Agriculture, Department of Agricultural and Life Sciences, Division of Animal Science
Research activity information
Award
- 2024
Japanese Society of Animal Science, JSAS Excellent Presentation Award - 2023
Japanese Society for Lactic Acid Bacteria, Excellence Award for Poster Presentation - 2022
Shinshu University, Patron’s Award - 2021
Japanese Society of Animal Science, English Presentation Award - 2020
Shinshu University, Patron’s Award - 2019
Japanese Dairy Science Association, Young Poster Award of Dairy Science Symposium in 2019
Paper
- Genetically Modified Lactococcus lactis Hypersecreting IL‐1Ra Improves Glucose Metabolism and Modulates the Gut Microbiota in an Obese Mouse Model
Masahiro Yoda; Natsumi Nomura; Shoko Yoda; Mao Kagotani; Aito Murakami; Fu Namai; Tadashi Fujii; Takumi Tochio; Takashi Sato; Takeshi Shimosato
Journal of Diabetes Research, 2026(1), Jan. 2026
- CpG-ODN from Streptococcus thermophilus as a tool for inducing extrinsic apoptosis via caspase-8 activation in mouse splenocytes.
Md Rayhan Chowdhury; Takuma Okajima; Aito Murakami; Ariful Islam; Takeshi Shimosato
Journal of immunological methods, 545, 113999-113999, Dec. 2025 - Construction of genetically modified lactic acid bacteria producing an Anti-Interleukin-31 receptor A Single-chain variable fragment.
Aito Murakami; Hotaru Ikeda; Masahiro Yoda; Fu Namai; Takashi Sato; Takeshi Shimosato
Molecular biology reports, 53(1), 81-81, Nov. 2025 - Ribosome-engineered Lacticaseibacillus rhamnosus GG with enhanced adhesion and immune activation via surface moonlighting proteins.
Masami Tsukagoshi; Jamiyanpurev Soyolmaa; Shunsaku Nomoto; Fu Namai; Aito Murakami; Kazuma Inoue; Masahiro Yoda; Tomoyuki Hibi; Takashi Sato; Hideki Kinoshita; Takeshi Shimosato
Microbiology spectrum, 13(12), e0263525, Oct. 2025 - Development of a Genetically Modified Lactococcus lactis Strain that Produces a Single-Chain Variable Fragment Targeting Interleukin-6 Receptor α to Suppress Serum Amyloid A.
Masahiro Yoda; Kaho Suzuki; Shoko Yoda; Kazuma Inoue; Mao Kagotani; Misato Kubo; Aito Murakami; Fu Namai; Takashi Sato; Takeshi Shimosato
Current microbiology, 82(11), 522-522, Sep. 2025 - Development of engineered IL-36γ-hypersecreting Lactococcus lactis to improve the intestinal environment.
Masahiro Yoda; Shogo Takase; Kaho Suzuki; Aito Murakami; Fu Namai; Takashi Sato; Tadashi Fujii; Takumi Tochio; Takeshi Shimosato
World journal of microbiology & biotechnology, 40(11), 363-363, Oct. 2024 - Ad libitum feeding of silkworm larvae powder-containing diets specifically influences metabolism-related and short-chain fatty acid-producing gut bacteria in mice.
Aito Murakami; Haruka Yamaguchi; Fu Namai; Takashi Sato; Maki Yamazaki; Hiroshi Uehara; Tadashi Fujii; Takumi Tochio; Kunihiro Shiomi; Takeshi Shimosato
Frontiers in cellular and infection microbiology, 14, 1383774-1383774, 2024 - Koji amazake produced by double saccharification contains more isomaltose and modifies the gut microbiota in mice.
Aito Murakami; Atsushi Saito; Fu Namai; Tadashi Fujii; Takumi Tochio; Jinichi Toida; Takeshi Shimosato
Frontiers in nutrition, 11, 1489912-1489912, 2024 - Oral administration of Limosilactobacillus ingluviei C37 inhibits Campylobacter jejuni colonization in chicks.
Aito Murakami; Ayako Watanabe-Yanai; Taketoshi Iwata; Fu Namai; Takashi Sato; Tadashi Fujii; Takumi Tochio; Sutisa Khempaka; Takeshi Shimosato
Frontiers in microbiology, 15, 1491039-1491039, 2024 - Oral administration of Brevibacterium linens from washed cheese increases the proportions of short-chain fatty acid-producing bacteria and lactobacilli in the gut microbiota of mice.
Aito Murakami; Koharu Toyomoto; Fu Namai; Takashi Sato; Tadashi Fujii; Takumi Tochio; Takeshi Shimosato
Animal science journal = Nihon chikusan Gakkaiho, 94(1), e13905, 2023
MISC
- Intratracheal therapy using nintedanib amorphous particles in murine pulmonary fibrosis
Kaho Suzuki; Fu Namai; Aito Murakami; Yuichi Sato; Akihiro Kotsugai; Takeshi Shimosato; Takashi Sato
Idiopathic interstitial pneumonias, OA4557 - OA4557, 14 Sep. 2024
https://syndication.highwire.org/content/doi/10.1183/13993003.congress-2024.OA4557
Lectures, oral presentations, etc.
- Brevibacterium linens as a Beneficial Dairy Microorganism: Immunostimulatory Effects and Promotion of Lactobacillus Growth via Oral Intake
Aito Murakami; Takeshi Shimosato
IDF World Dairy Summit, Nov. 2026IMMUNOMODULATORY PROPERTIES OF LIMOSILACTOBACILLUS INGLUVIEI AND ITS EFFICACY AGAINST CAMPYLOBACTER JEJUNI COLONIZATION IN CHICKS
Aito Murakami, Takeshi Shimosato
VII International Symposium on Lactic Acid Bacteria, Aug. 2026, InvitedEvaluation of Interleukin-36γ Producing Genetically Modified Lactic Acid Bacteria for an Intestinal Environment
Aito Murakami; Masahiro Yoda; Fu Namai; Takashi Sato; Takeshi Shimosato
Asian Federation of Societies for Lactic Acid Bacteria 15 (AFSLAB15), Nov. 2025ジャージー種由来腸内細菌叢の解析とセルロース分解菌の分離
久保美怜; 籠谷万音; 村上愛斗; 生井楓; 下里剛士
酪農科学シンポジウム2025Limosilactobacillus ingluviei C37投与が幼雛腸管で示すCampylobacter jejuniの定着阻害効果
村上愛斗; 生井楓; Khempaka Sutisa; 下里剛士
酪農科学シンポジウム2025NicXを産生するLactococcus lactis組換え体の構築
中村英美華; 依田将宏; 村上愛斗; 生井楓; 下里剛士
酪農科学シンポジウム2025Lacticaseibacillus rhamnosus GGにおけるrpsL遺伝子変異がもたらす免疫賦活能の変化
野本駿作; 村上愛斗; 井上和真; 依田将宏; 生井楓; 下里剛士
酪農科学シンポジウム2025抗IL-31Ra低分子抗体を産生するLactococcus lactis 組換え体の構築と機能評価
村上愛斗; 生井楓; 下里剛士
2025年度日本乳酸菌学会大会Brevibacterium linensの経口投与はマウスの腸管内で乳酸菌や短鎖脂肪酸産生菌の増殖を促す
村上愛斗; 下里剛士
日本畜産学会第131回大会抗インターロイキン6Rα低分子抗体を産生する乳酸菌組換え体の抗炎症作用
依田将宏; 村上愛斗; 生井楓; 下里剛士
日本畜産学会第131回大会抗LAG-3低分子抗体を産生する乳酸菌組換え体の構築
梶村彩香; 依田将宏; 村上愛斗; 下里剛士
酪農科学シンポジウム2024プレバイオティクスが関節炎モデルマウスにもたらす影響
中田梨央; 村上愛斗; 依田将宏; 下里剛士
酪農科学シンポジウム2024Limosilactobacillus ingluviei C37投与は肉用鶏ブロイラー幼雛腸管内でのCampylobacter jejuniの定着を阻害する
村上愛斗; 渡部綾子; 下里剛士
2024年度日本乳酸菌学会Administration of probiotics in one-week-old chicks suppresses Campylobacter jejuni colonization
Aito Murakami; Ayako Watanabe-Yanai; Takeshi Shimosato
Joint AAAP and AAAS Animal Production Congress 2024免疫チェックポイント阻害乳酸菌の経鼻投与による原発性肺ガンの抑制効果（若手優秀ポスター賞 受賞）
野村奈津実; 生井楓; 村上愛斗; 佐藤隆; 下里剛士
酪農科学シンポジウム2023IL-36γを産生するLactococcus lactis組換え体によるムチン産生促進作用
髙瀨渉吾、生井楓、村上愛斗、佐藤隆、下里剛士
酪農科学シンポジウム2023Construction of genetically modified lactic acid bacteria producing anti-IL31Ra single-chain Fragment variable (English Presentation Award)
Aito Murakami; Fu Namai; Suguru Shigemori; Ogita Tasuku; Takeshi Shimosato
The 129th Annual Meeting of Japanese Society of Animal Science抗PD-L1scFvを分泌する乳酸菌組換え体の構築
村上愛斗; 生井楓; 重盛駿; 荻田佑; 下里剛士
日本畜産学会第128回大会