SUZUKI Emi
School of Medicine Department of Molecular & Cellular Physiology
Assistant Professor
Researcher Information
Research Keyword
- IQSEC2, CRISPR/Cas9, CASK, synapse
Career
Research activity information
Paper
- Deep-Learning-Based Analysis Reveals a Social Behavior Deficit in Mice Exposed Prenatally to Nicotine
Mengyun Zhou 1, Wen Qiu , Nobuhiko Ohashi, Lihao Sun, Marie-Louis Wronski, Emi Kouyama-Suzuki, Yoshinori Shirai, Toru Yanagawa, Takuma Mori and Katsuhiko Tabuchi
Cells., 13(3), Feb. 2024, Refereed
- Structural Analysis Implicates CASK-Liprin-α2 Interaction in Cerebellar Granular Cell Death in MICPCH Syndrome
Qi Guo, Emi Kouyama-Suzuki, Yoshinori Shirai 1, Xueshan Cao, Toru Yanagawa, Takuma Mori, and Katsuhiko Tabuchi
Cells., 12(8), Apr. 2023, Refereed - An Epilepsy-Associated Mutation of Salt-Inducible Kinase 1 Increases the Susceptibility to Epileptic Seizures and Interferes with Adrenocorticotropic Hormone Therapy for Infantile Spasms in Mice
Bo Pang, Takuma Mori, Moataz Badawi, Mengyun Zhou, Qi Guo, Emi Suzuki-Kouyama, Toru Yanagawa, Yoshinori Shirai, and Katsuhiko Tabuchi
International Journal of Molecular Sciences, 23(14), Jul. 2022, Refereed - IQSEC3 Deletion Impairs Fear Memory Through Upregulation of Ribosomal S6K1 Signaling in the Hippocampus
Dongwook Kim, Hyeji Jung, Yoshinori Shirai, Hyeonho Kim, Jinhu Kim, Dongseok Lim, Takuma Mori, Hyojeong Lee, Dongseok Park, Hee Young Kim, Qi Guo, Bo Pang, Wen Qiu, Xueshan Cao, Emi Kouyama-Suzuki, Takeshi Uemura, Enas Kasem, Yu Fu, Seungjoon Kim, Akinori Tokunaga, Takahiro Yoshizawa, Tatsuo Suzuki, Hiroyuki Sakagami, Kea Joo Lee, Jaewon Ko, Katsuhiko Tabuchi, and Ji Won Um
Biological Psychiatry, 91(9), 821-831, May 2022, Refereed - Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
Takeshi Uemura , Emi Suzuki-Kouyama, Shiori Kawase , Taiga Kurihara , Misato Yasumura , Tomoyuki Yoshida , Shuya Fukai, Maya Yamazaki, Peng Fei , Manabu Abe , Masahiko Watanabe , Kenji Sakimura, Masayoshi Mishina , Katsuhiko Tabuchi
Cell Report., 39(1), Apr. 2022, Refereed - IQSEC2 Deficiency Results in Abnormal Social Behaviors Relevant to Autism by Affecting Functions of Neural Circuits in the Medial Prefrontal Cortex
Anuradha Mehta, Yoshinori Shirai, Emi Kouyama-Suzuki, Mengyun Zhou, Takahiro Yoshizawa, Toru Yanagawa, Takuma Mori, and Katsuhiko Tabuchi
Cells., 10(10), Oct. 2021, Refereed - Risperidone Mitigates Enhanced Excitatory Neuronal Function and Repetitive Behavior Caused by an ASD-Associated Mutation of SIK1.
Badawi M, Mori T, Kurihara T, Yoshizawa T, Nohara K, Kouyama-Suzuki E, Yanagawa T, Shirai Y, Tabuchi K.
Front Mol Neurosci., 14, Jul. 2021, Refereed - Inhibition of DNA ligase IV enhances the CRISPR/Cas9-mediated knock-in efficiency in mouse brain neurons.
Cao X, Kouyama-Suzuki E, Pang B, Kurihara T, Mori T, Yanagawa T, Shirai Y, Tabuchi K.
Biochem Biophys Res Commun., 533(3), 449-457, Dec. 2020, Refereed - DNA repair protein RAD51 enhances the CRISPR/Cas9-mediated knock-in efficiency in brain neurons.
Kurihara T, Kouyama-Suzuki E, Satoga M, Li X, Badawi M, Thiha, Baig DN, Yanagawa T, Uemura T, Mori T, Tabuchi K.
Biochem Biophys Res Commun., 524(3), 621-628, Apr. 2020, Refereed - X染色体不活性化による発現/欠損細胞のモザイク分布と機能異常
森 琢磨, Kasem Enas, 鈴木 絵美, 曹 雪杉, 栗原 大河, 田渕 克彦
日本生理学雑誌, 82(1), 2, Feb. 2020 - 塩誘導性キナーゼ1変異を有するてんかんマウスにおけるシナプス異常および行動障害(Synaptic and behavioral deficits in mice with an epilepsy-associated mutation of salt induced kinase 1
森 琢磨, Badawi Moataz, 鈴木 絵美, 栗原 大河, 野原 克裕, 吉沢 隆浩, 田渕 克彦
てんかん研究, 37(2), 515, Sep. 2019 - Deficiency of calcium/calmodulin-dependent serine protein kinase disrupts the excitatory-inhibitory balance of synapses by down-regulating GluN2B.
Mori T, Kasem EA, Suzuki-Kouyama E, Cao X, Li X, Kurihara T, Uemura T, Yanagawa T, Tabuchi K
Mol Psychiatry., 24(7), Jan. 2019, Refereed - 新規PDYN変異が見出された脊髄小脳変性症23型2家系の臨床的、細胞生物学的検討
近藤 恭史, 佐藤 俊一, 大原 愼司, 鈴木 絵美, 宮崎 大吾, 中村 勝哉, 山口 智美, 石川 真澄, 涌井 敬子, 古庄 知己, 福嶋 義光, 関島 良樹, 吉田 邦広
臨床神経学, 58(Suppl.), S265, Dec. 2018 - Adult onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) and Nasu-Hakola disease: lesion staging and dynamic changes of axons and microglial subsets
Oyanagi K, Kinoshita M, Suzuki-Kouyama E, Inoue T, Nakahara A, Tokiwai M, Arai N, Satoh JI, Aoki N, Jinnai K, Yazawa I, Arai K, Ishihara K, Kawamura M, Ishizawa K, Hasegawa K, Yagisita S, Amano N, Yoshida K, Terada S, Yoshida M, Akiyama H, Mitsuyama Y, Ikeda SI
BRAIN PATHOLOGY, 27(6), 748-769, Nov. 2017, Refereed - A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2
Sakai E, Miura Y, Suzuki-Kouyama E, Oka K, Tachibana M, Kawabata K, Sakurai F, Mizuguchi H
SCIENTIFIC REPORTS, Jul. 2017, Refereed - Axonal TDP-43 aggregates in sporadic amyotrophic lateral sclerosis.
Onozato T, Nakahara A, Suzuki-Kouyama E, Hineno A, Yasude T, Nakamura T, Yahikozawa H, Watanabe M, Kayanuma K, Makishita H, Ohara S, Hashimoto T, Higuchi K, Sakai T, Asano K, Hashimoto T, Kanno H, Nakayama J, Oyanagi K.
Neurophathol Appl Neurobiol., 42(6), 561-572, Oct. 2016, Refereed - "Gliomatosis encephali" as a novel category of brain tumors by the first autopsy case report of gliomatosis cerebelli
Asa Nakahara , Toshikazu Yoshida, Masanobu Yazawa, Takashi Ehara, Jun Nakayama, Akiyoshi Kakita, Ryosuke Ogura, Mika Asakawa, Emi Suzuki-Kouyama, Kiyomitsu Oyanagi
Neurp@athology, 34(3), 295-303, Jun. 2014, Refereed - 4 多系統萎縮症とレビー小体病 : シヌクレイノパチーの合併剖検例（Ⅰ. 一般演題, 第39回上信越神経病理懇談会）
小柳 清光; 木下 朋実; 浅川 美果; 鈴木 絵美; 矢澤 正信
新潟医学会雑誌, 128(4), 190-190, Apr. 2014 - Distinctive features of degenerating Purkinje cells in spinocerebellar ataxia type 31
Yoshida K, Asakawa M, Suzuki-Kouyama E, Tabata K, Shintaku M, Ikeda S, Oyanagi K.
Neuropathology., 34(3), 261-267, Jan. 2014, Refereed - マイクロRNAを手掛かりとした新規血管新生制御遺伝子の同定と機能解析
三浦裕介、 酒井英子 、成井信博、香山絵美、櫻井文教、川端健二、水口裕之
日本薬学会年会要旨集, 132(4), 179, 05 Mar. 2012 - Hexon-specific PEGylated adenovirus vectors utilizing avidin-biotin interaction.
Suzuki-Kouyama E, Katayama K, Sakurai F, Yamaguchi T, Kurachi S, Kawabata K, Nakagawa S, Mizuguchi H.
Biomaterials., 32(6), 1724-1730, Feb. 2011, Refereed
Lead - Induction of type I interferon by adenovirus-encoded small RNAs.
Yamaguchi T, Kawabata K, Kouyama E, Ishii KJ, Katayama K, Suzuki T, Kurachi S, Sakurai F, Akira S, Mizuguchi H.
Proc Natl Acad Sci U S A., 107(40), 17286-17291, Sep. 2010, Refereed - miR-122a-Regulated Expression of a Suicide Gene Prevents Hepatotoxicity Without Altering Antitumor Effects in Suicide Gene Therapy.
Suzuki T, Sakurai F, Nakamura SI, Kouyama E, Kawabata K, Kondoh M, Yagi K, Mizuguchi H.
Oct. 2008 - Analysis of B cell selection in the germinal center reaction during a T-dependent antibody response at a single cell level.
Okazawa T, Magari M, Kimoto T, Kouyama E, Ohmori H, Kanayama N.
Immunol Lett., 117(1), 96-105, Apr. 2008, Refereed - Analysis of antigen-stimulated B cell migration into germinal centers during the early stage of a T-dependent immune response.
Kouyama E, Nishikawa Y, Okazawa T, Magari M, Ohmori H, Kanayama N.
Immunol Lett., 109(1), 28-35, Jan. 2007, Refereed
Lead
