TANAKA Sachi
Academic Assembly School of Science and Technology Institute of Agriculture
Faculty of Agriculture Department of Agricultural and Life Sciences Division of Animal Science
Professor
Researcher Information
Research activity information
Paper
- Antitumor Effect of Apilactobacillus kosoi 10H by Inducing Immunostimulatory Macrophages.
Takahashi F, Chiou TY, Tsukamoto M, Moriyama S, Takahashi T, Tanaka S.
Cellular Microbiology., 2025(1), 4115145, Feb. 2025 - Mechanisms of interleukin-10 induction in murine spleen and RAW264 cells by Latilactobacillus curvatus K4G4 isolated from fermented Brassica rapa L.
Okano A, Tanaka S, Yamada K, Hashimoto N, Watanabe J.
Biosci Microbiota Food Health., 43(3), 227-233, May 2024 - Heat-killed Lactiplantibacillus plantarum Shinshu N-07 exerts antiobesity effects in western diet-induced obese mice.
Tanaka Y, Inaba C, Sawa T, Endo K, Saiki T, Haga H, Niitsuma F, Kawahara T, Watanabe J, Tanaka S.
J Appl Microbiol., 135(5), lxae119, May 2024 - Characterization and anti-tumor activities of polysaccharide isolated from Brassica rapa L. via activation of macrophages through TLR2-and TLR4-Dependent pathways.
Matsui R, Endo K, Saiki T, Haga H, Shen W, Wang X, Yamazaki S, Katayama S, Nagata K, Kitamura H, Tanaka S.
Arch Biochem Biophys., 752, 109879, Feb. 2024 - Oral administration of procyanidin B2 3,3"-di-O-gallate ameliorates experimental autoimmune encephalomyelitis through immunosuppressive effects on CD4+ T cells by regulating glycolysis.
Endo K, Sawa T, Tanaka Y, Saiki T, Haga H, Rizeq L, Aso H, Isono M, Niitsuma F, Masaki A, Makabe H, Tanaka S.
European Journal of Pharmacology, 954, 175879, Jul. 2023 - Brassica rapa L. prevents Western diet-induced obesity in C57BL/6 mice through its binding capacity of cholesterol and fat.
Tanaka Y, Inaba C, Sawa T, Endo K, Saiki T, Haga H, Tanaka S.
Biomed Pharmacother., 86, Jun. 2023 - Procyanidin B2 3,3''-di-O-gallate ameliorates imiquimod-induced skin inflammation by suppressing TLR7 signaling through the inhibition of endosomal acidification in dendritic cells.
Sawa T, Endo K, Nakashima A, Tanaka Y, Makabe H, Tanaka S
International Immunopharmacology., 121, 110444, Jun. 2023 - Modulation of immune function and changes in intestinal flora by Brassica rapa L. (Nozawana).
Sashi Tanaka
Biosci Biotechnol Biochem., 87(5), 465-472, Apr. 2023 - Procyanidin B2 3,3″-di-O-gallate suppresses IFN-γ production in murine CD4+ T cells through the regulation of glutamine influx via direct interaction with ASCT2.
Endo K, Sawa T, Kitamura H, Umezawa K, Makabe H, Tanaka S.
International Immunopharmacology., 115, 109617, Dec. 2022 - Long-term caloric restriction ameliorates T cell immunosenescence in mice.
Asami T, Endo K, Matsui R, Sawa T, Tanaka Y, Saiki T, Tanba N, Haga H, Tanaka S.
Mech Ageing Dev., 206, 111710, 20 Jul. 2022 - Metabolomic evaluation of different starter culture effects on water-soluble and volatile compound profiles in nozawana pickle fermentation.
Tomita S, Watanabe J, Kuribayashi T, Tanaka S, Kawahara T.
Food Chemistry: Molecular Sciences., 2, 100019, Jul. 2022 - Dietary Supplementation with Fermented Brassica rapa L. Stimulates Defecation Accompanying Change in Colonic Bacterial Community Structure.
Tanaka S, Yamamoto K, Hamajima C, Takahashi F, Endo K, Uyeno Y.
Nutrients, 13(6), 1847, May 2021 - Brassica rapa L. activates macrophages via Toll-like receptors.
Takahashi F, Endo K, Matsui R, Yamamoto K, Tanaka S.
Biosci Biotechnol Biochem., 85(3), 656-665, 24 Feb. 2021 - The suppression of IL-17 production from T cells by gallate-type procyanidin is mediated by selectively inhibiting cytokine production from dendritic cells.
Endo K, Matsui R, Asami T, Sawa T, Nakashima A, Tanaka Y, Makabe H, Tanaka S.
Biomed Pharmacother., 137, 111346, 05 Feb. 2021 - Procyanidin B2 gallate regulates TNF-alpha production from T cells through inhibiting glycolytic activity via mTOR-HIF-1 pathway
Endo, Katsunori; Matsui, Rina; Sugiyama, Momona; Asami, Takuya; Inaba, Chihiro; Kobayashi, Shuhei; Makabe, Hidefumi; Tanaka, Sachi;
Biochemical Pharmacology, 177, Jul. 2020
- MicroRNA 16-5p is upregulated in calorie-restricted mice and modulates inflammatory cytokines of macrophages.
Yamada K, Takizawa S, Ohgaku Y, Asami T, Furuya K, Yamamoto K, Takahashi F, Hamajima C, Inaba C, Endo K, Matsui R, Kitamura H, Tanaka S.
GENE, 725, 144191, Jan. 2020 - Transcriptome analysis of the effect of C-C chemokine receptor 5 deficiency on cell response to Toxoplasma gondii in brain cells.
Kobayashi K, Umeda K, Ihara F, Tanaka S, Yamagishi J, Suzuki Y, Nishikawa Y.
BMC Genomics., 20, 705, Sep. 2019 - Involvement of Toll-like receptor 2 in the cerebral immune response and behavioral changes caused by latent Toxoplasma infection in mice.
Ihara F, Tanaka S, Fereig RM, Nishimura M, Nishikawa Y.
PLoS One., 14, e0220560, Aug. 2019 - Characterization of Microbiota that Influence Immunomodulatory Effects of Fermented Brassica rapa L.
Bayanjargal Sandagdorj, Chisato Hamajima, Takeshi Kawahara, Jun Watanabe, Sachi Tanaka
Microbes and Environments, 34, 206-214, Jun. 2019 - Enhanced Anti-Allergic Activity of Milk Casein Phosphopeptide by Additional Phosphorylation in Ovalbumin-Sensitized Mice.
Lebetwa N, Suzuki Y, Tanaka S, Nakamura S, Katayama S.
MOLECULES, 24, E738, Feb. 2019 - Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain.
Shimizu A, Mitani T, Tanaka S, Fujii H, Maebuchi M, Amiya Y, Tanaka M, Matsui T, Nakamura S, Katayama S.
J Agric Food Chem., 66(30), 7935-7941, 01 Aug. 2018 - Enhancement of natural killer activity and IFN-γ production in an IL-12-dependent manner by a Brassica rapa L.
Yamamoto K, Furuya K, Yamada K, Takahashi F, Hamajima C, and Tanaka S.
Bioscience, Biotechnology, and Biochemistry., 82, 654-668, Apr. 2018 - Transcriptional profiling 1 of Toll-like receptor 2-deficient primary murine brain cells during Toxoplasma gondii infection.
Umeda K, Tanaka S, Ihara F, Yamagishi J, Suzuki Y, and Nishikawa Y.
PLoS One., 12, e0187703, 06 Nov. 2017 - Changes in Gut Microbial Ecology and Immunological Responses of Mice Fed the Insoluble Fraction of Brassica rapa L. that was Fermented or Not.
Tanaka S, Furuya K, Yamamoto K, Yamada K, Ichikawa M, Suda M, Makabe H.
Microbes and Environments, 32, 268-274, Sep. 2017 - Procyanidin B2 gallates inhibit IFN-γ and IL-17 production in T cells by suppressing T-bet and RORγt expression.
Tanaka S, Furuya K, Yamamoto K, Yamada K, Ichikawa M, Suda M, Makabe H.
International Immunopharmacology., 44, 87-96, Mar. 2017 - Relationship of enhanced butyrate production by colonic butyrate-producing bacteria and immunomodulatory effects in normal mice fed insoluble fraction of Brassica rapa L..
Tanaka S, Yamamoto K, Yamada K, Furuya K, Uyeno Y.
Applied and Environmental Microbiology., 82, 2693-2699, Apr. 2016 - Transcriptome and Histopathological Changes in Mouse Brain Infected with Neospora caninum.
Nishimura M, Tanaka S, Ihara F, Muroi Y, Yamagishi J, Furuoka H, Suzuki Y, Nishikawa Y.
Scientific Reports., 5, 7936, Jan. 2015 - Antioxidant and cytoprotective activities of extracts prepared from fruit and vegetable wastes and by-products.
Kabir F, Tow WW, Hamauzu Y, Katayama S, Tanaka S, Nakamura S,
Food Chemistry, 15, 358-362, Jan. 2015 - Role of the chemokine receptor CCR5-dependent host defense system in Neospora caninum infections.
Abe C, Tanaka S, Nishimura M, Ihara F, Xuan X, Nishikawa Y.
Parasites & Vectors., 8, 5, Jan. 2015 - Inhibitory/suppressive oligodeoxynucleotide nanocapsules as simple oral delivery devices for preventing atopic dermatitis in mice.
Wang Y, Yamamoto Y, Shigemori S, Watanabe T, Oshiro K, Wang X, Wang P, Sato T, Yonekura S, Tanaka S, Kitazawa H, Shimosato T.
Molecular Therapy., 23(2), 297-309, 2015 - Plasmodium berghei circumsporozoite protein encapsulated in oligomannose-coated liposomes confers protection against sporozoite infection in mice.
Terkawi MA, Kuroda Y, Fukumoto S, Tanaka S, Kojima N, Nishikawa Y.
Malaria Journal., 13, 426, Nov. 2014 - Macrophage depletion prior to Neospora caninum infection results in severe neosporosis in mice.
Abe C, Tanaka S, Ihara F, Nishikawa Y,
Clinical and Vaccine Immunology, 21, 1185-1188, Aug. 2014 - Vaccination with profilin encapsulated in oligomannose-coated liposomes induces significant protective immunity against Toxoplasma gondii
Tanaka S, Kuroda Y, Ihara F, Nishimura M, Hiasa J, Kojima N, Nishikawa Y.
Vaccine, 32, 1781-1785, Apr. 2014 - Overproduction of Toxoplasma gondii cyclophilin-18 regulates host cell migration and enhances parasite dissemination in a CCR5-independent manner
Ibrahim HM, Nishimura M, Tanaka S, Awadin W, Furuoka H, Xuan X, Nishikawa Y.
BMC Microbiology, 14, 76, Mar. 2014 - Transcriptome Analysis of Mouse Brain Infected with Toxoplasma gondii
Tanaka S, Nishimura M, Ihara F, Yamagishi J, Suzuki Y, Nishikawa Y
Infection and Immunity, 81(10), 3609-3619, Oct. 2013 - Oligomannose-coated liposome-entrapped dense granule protein 7 induces protective immune response to Neospora caninum in cattle
Nishimura M, Kohara J, Kuroda Y, Hiasa J, Tanaka S, Muroi Y, Kojima N, Furuoka H, Nishikawa Y
Vaccine, 31(35), 3528-3535, Aug. 2013 - Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner
Koizumi SI, Masuko K, Wakita D, Tanaka S, Mitamura R, Kato Y, Tabata H, Nakahara M, Kitamura H, Nishimura T
CELLULAR IMMUNOLOGY, 276, 153-161, Apr. 2012 - Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L.
Tanaka S, Koizumi S, Masuko K, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Ohkuri T, Wakita D, Chamoto K, Kitamura H, Nishimura T
International Immunopharmacology, 11, 226-232, 2011 - The extract of Japanese soybean, Kurosengoku activates the production of IL-12 and IFN-γ by DC or NK1.1(+) cells in a TLR4- and TLR2-dependent manner
Tanaka S, Koizumi S, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Wakita D, Chamoto K, Kitamura H, Nishimura T
CELLULAR IMMUNOLOGY, 266, 135-142, 2011 - Intrauterine administration of peripheral blood mononuclear cells enhances early development of the pre-implantation bovine embryo
Ideta A, Hayama K, Nakamura Y, Sakurai T, Tsuchiya K, Tanaka S, Yamaguchi T, Fujiwara H, Imakawa K, Aoyagi Y
Molecular Reproduction and Development, 77, 954-962, 2010 - Transcytosis of murine-adapted bovine spongiform encephalopathy agents in an in vitro bovine M cell model
Miyazawa K, Kanaya T, Takakura I, Tanaka S, Hondo T, Watanabe H, Rose MT, Kitazawa H, Yamaguchi T, Katamine S, Nishida N, Aso H
Journal of virology, 84, 12285-12291, 2010 - Characterization of newly established bovine intestinal epithelial cell line
Miyazawa K, Hondo T, Kanaya T, Tanaka S, Takakura I, Itani W, Rose MT, Kitazawa H, Yamaguchi T, Aso H
HISTOCHEMISTRY AND CELL BIOLOGY, 133, 125-134, 2010 - Differential responses between monocytes and monocyte-derived macrophages for lipopolysaccharide stimulation of calves
Guo Y, Zhao G, Tanaka S, Yamaguchi T
Cellular&Molecular Immunology, 6, 223-229, 2009 - Expression of hyaluronan synthase 1 and distribution of hyaluronan during follicular atresia in pig ovaries
Miyake Y, Sakurai M, Tanaka S, Tunjung WA, Yokoo M, Matsumoto H, Aso H, Yamaguchi T, Sato E
BIOLOGY OF REPRODUCTION, 80, 249-257, 2009 - Anterior pituitary progenitor cells express costimulatory molecule 4Ig-B7-H3
Nagai Y, Aso H, Ogasawara H, Tanaka S, Taketa Y, Watanabe K, Ohwada S, Rose MT, Kitazawa H, Yamaguchi T
JOURNAL OF IMMUNOLOGY, 181, 6073-6081, 2008 - Presence of neuropeptide Y in somatotrophs of cattle
Ogasawara H, Aso H, Nagai Y, Matsumoto K, Okumura H, Tanaka S, Watanabe K, Ohwada S, Yamaguchi T
DOMESTIC ANIMAL ENDOCRINOLOGY, 35, 274-280, 2008 - Differential cytokine expression in T cell subsets from bovine peripheral blood
Tanaka S, Nagai Y, Noguchi Y, Miyake M, Watanabe K, Ohwada S, Aso H, Yamaguchi T
ANIMAL SCIENCE JOURNAL, 79, 597-604, 2008 - Localization of leptin and leptin receptor in the bovine adenohypophysis
Ogasawara H, Ohwada S, Nagai Y, Taketa Y, Matsuzaki M, Tanaka S, Watanabe K, Aso H, Yamaguchi T
DOMESTIC ANIMAL ENDOCRINOLOGY, 35, 8-15, 2008 - Differential expression of myostatin and its receptor in the porcine anterior pituitary gland
Taketa Y, Nagai Y, Ogasawara H, Hayashi S, Miyake M, Tanaka S, Watanabe K, Ohwada S, Aso H, Yamaguchi T
ANIMAL SCIENCE JOURNAL, 79, 382-390, 2008 - Age-related changes in leukocytes and T cell subsets in peripheral blood of Japanese Black cattle
Tanaka S, Miyazawa K, Kuwano A, Watanabe K, Ohwada S, Aso H, Nishida S, Yamaguchi T
ANIMAL SCIENCE JOURNAL, 79, 368-374, 2008 - Myostatin and MyoD family expression in skeletal muscle of IGF-1 knockout mice
Miyake M, Hayashi S, Sato T, Taketa Y, Watanabe K, Hayashi S, Tanaka S, Ohwada S, Aso H, Yamaguchi T
CELL BIOLOGY INTERNATIONAL, 3, 1274-1279, 2007 - Differential cytokine gene expression in CD4+ and CD8+ T cell subsets of calves
Tanaka S, Aso H, Miyazawa K, Nagai Y, Watanabe K, Ohwada S, Kobayashi J, Yamaguchi T
Veterinary Immunology and Immunopathology, 118, 84-91, 2007 - Immunohistochemical characterization of cell types expressing the cellular prion protein in the small intestine of cattle and mice
Miyazawa K, Kanaya T, Tanaka S, Takakura I, Watanabe K, Ohwada S, Kitazawa H, Rose MT, Sakaguchi S, Katamine S, Yamaguchi T, Aso H
HISTOCHEMISTRY AND CELL BIOLOGY, 127, 291-301, 2007 - Comparison of T cell subsets between somatic cloned and normal cow
Tanaka S, Miyazawa K, Watanabe K, Ohwada S, Aso H, Yonai M, Saito N, Yamaguchi T
American Journal of Reproductive Immunology, 55, 28-35, 2006
