博士（医学）, 岡山大学

Respiratory surgery, lung cancer

2000 - 2006, 岡山大学大学院医歯薬学総合研究科, 医学研究科, 外科系専攻

1994 - 2000, Sapporo Medical University, 医学部, 医学科

2019
第36回日本呼吸器外科学会, 呼吸器外科学会賞
International academic award

2018
第72回手術手技研究会, ビデオ賞
International academic award

2007
12th World Conference of Lung Cancer, Lectureship- Ginsberg award
International academic award

Efficacy, Safety, and Influence on the Tumor Microenvironment of Neoadjuvant Pembrolizumab plus Ramucirumab for PD-L1-Positive NSCLC: A Phase II Trial (EAST ENERGY).
Keiju Aokage; Shohei Koyama; Shogo Kumagai; Kotaro Nomura; Yoshihisa Shimada; Kiyotaka Yoh; Masashi Wakabayashi; Miki Fukutani; Hideki Furuya; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Tetsuro Taki; Takuo Hayashi; Jun Matsubayashi; Genichiro Ishii; Hiroyoshi Nishikawa; Norihiko Ikeda; Masahiro Tsuboi
Clinical cancer research : an official journal of the American Association for Cancer Research, 30(24), 5584-5592, Dec. 2024
Lead

The effect of epidermal growth factor receptor mutation on adjuvant chemotherapy with tegafur/uracil for patients with completely resected, non-lymph node metastatic non-small cell lung cancer (> 2 cm): a multicenter, retrospective, observational study as exploratory analysis of the CSPOR-LC03 study.
Tomohiro Miyoshi; Keiju Aokage; Shun-Ichi Watanabe; Hiroyuki Ito; Noriaki Sakakura; Mingyon Mun; Motohiro Yamashita; Yasuhisa Ohde; Tadashi Aoki; Wataru Nishio; Masataka Taguri; Masahiro Tsuboi
Japanese journal of clinical oncology, Sep. 2024
Lead

A novel histopathological feature of spatial tumor-stroma distribution predicts lung squamous cell carcinoma prognosis.
Tetsuro Taki; Yutaro Koike; Masahiro Adachi; Shingo Sakashita; Naoya Sakamoto; Motohiro Kojima; Keiju Aokage; Shumpei Ishikawa; Masahiro Tsuboi; Genichiro Ishii
Cancer science, Sep. 2024
Lead

Lymph node dissection in small peripheral lung cancer: Supplemental analysis of JCOG0802/WJOG4607L.
Tomohiro Maniwa; Jiro Okami; Tomohiro Miyoshi; Masashi Wakabayashi; Hiroshige Yoshioka; Takahiro Mimae; Makoto Endo; Aritoshi Hattori; Kazuo Nakagawa; Tetsuya Isaka; Mitsuhiro Isaka; Ryosuke Kita; Yuta Sekino; Noriko Mitome; Keiju Aokage; Hisashi Saji; Ryu Nakajima; Morihito Okada; Masahiro Tsuboi; Hisao Asamura; Haruhiko Fukuda; Shun-Ichi Watanabe
The Journal of thoracic and cardiovascular surgery, 168(3), 674-683, Sep. 2024
Lead

Long-term outcomes of 5-year survivors without recurrence after the complete resection of non-small cell lung cancer after lobectomy: a landmark analysis in consideration of competing risks.
Yutaro Koike; Keiju Aokage; Masashi Wakabayashi; Takashi Ikeno; Ken Onodera; Joji Samejima; Tomohiro Miyoshi; Kenta Tane; Kenji Suzuki; Masahiro Tsuboi
Surgery today, 54(9), 1005-1014, Sep. 2024
Lead

What is the Optimal Resection Extent for Preserving Respiratory Function in Segmentectomy?: Insights on Lung Resection Volume and Respiratory Function.
Seiyu Jeong-Yoo Ohtani-Kim; Joji Samejima; Masashi Wakabayashi; Makoto Tada; Yutaro Koike; Tomohiro Miyoshi; Kenta Tane; Keiju Aokage; Masahiro Tsuboi
Annals of surgical oncology, 31(9), 5766-5767, Sep. 2024
Lead

Updated review of perioperative treatment for non-small-cell lung cancer in the new era of immune checkpoint inhibitors: past, present, and future.
Shun-Ichi Watanabe; Masaya Yotsukura; Tomohiro Miyoshi; Aritoshi Hattori; Tetsuya Isaka; Tomohiro Maniwa; Mitsuhiro Isaka; Hiroshige Yoshioka; Makoto Endo; Takahiro Mimae; Yasuhiro Tsutani; Kazuo Nakagawa; Keiju Aokage
Japanese journal of clinical oncology, Aug. 2024
Lead

The Lung Cancer Surgical Study Group of the Japan Clinical Oncology Group: outstanding contribution and entering a new phase.
Kazuo Nakagawa; Masaya Yotsukura; Takahiro Mimae; Aritoshi Hattori; Tomohiro Miyoshi; Mitsuhiro Isaka; Makoto Endo; Yasuhiro Tsutani; Tetsuya Isaka; Tomohiro Maniwa; Ryu Nakajima; Hiroshige Yoshioka; Hidefumi Takei; Keiju Aokage; Shun-Ichi Watanabe
Japanese journal of clinical oncology, Aug. 2024
Lead

A randomized phase III trial of postoperative surveillance for pathological stage II and IIIA non-small cell lung cancer (JCOG2012, PHOENIX).
Kenta Tane; Satoshi Shiono; Masashi Wakabayashi; Tomoko Kataoka; Noriko Mitome; Haruhiko Fukuda; Keiju Aokage; Shun-Ichi Watanabe
Japanese journal of clinical oncology, 54(8), 926-929, Aug. 2024
Lead

Prognostic significance of micronest in cancer stroma in resected lung squamous cell carcinoma.
Yasunori Kaminuma; Tokiko Nakai; Keiju Aokage; Tetsuro Taki; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Saori Miyazaki; Naoya Sakamoto; Shingo Sakashita; Motohiro Kojima; Reiko Watanabe; Masahiro Tsuboi; Genichiro Ishii
Human pathology, 150, 20-28, Aug. 2024
Lead

Prognostic value of the international association for the study of lung cancer grading system and its association with the tumor microenvironment in stage I EGFR-muted lung adenocarcinoma.
Shoko Kubota; Tetsuro Taki; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Keiju Aokage; Masashi Wakabayashi; Kotaro Nomura; Michiko Nagamine; Motohiro Kojima; Shingo Sakashita; Naoya Sakamoto; Masahiro Tsuboi; Genichiro Ishii
European journal of cancer (Oxford, England : 1990), 207, 114184-114184, Aug. 2024
Lead

Spatial intratumor heterogeneity of programmed death-ligand 1 expression predicts poor prognosis in resected non-small cell lung cancer.
Yusuke Nagasaki; Tetsuro Taki; Kotaro Nomura; Kenta Tane; Tomohiro Miyoshi; Joji Samejima; Keiju Aokage; Seiyu Jeong-Yoo Ohtani-Kim; Motohiro Kojima; Shingo Sakashita; Naoya Sakamoto; Shumpei Ishikawa; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Journal of the National Cancer Institute, 116(7), 1158-1168, Jul. 2024
Lead

A case of lung metastasis from gastric cancer presenting as ground-glass opacity dominant nodules.
Takahiro Niimi; Joji Samejima; Yutaro Koike; Tomohiro Miyoshi; Kenta Tane; Keiju Aokage; Tetsuro Taki; Genichiro Ishii; Masahiro Tsuboi
Journal of cardiothoracic surgery, 19(1), 365-365, Jun. 2024
Lead

Effect of Resected Lung Volume on Pulmonary Function and Residual Lung Volume in Patients Undergoing Segmentectomy: A Retrospective Study.
Seiyu Jeong-Yoo Ohtani-Kim; Joji Samejima; Masashi Wakabayashi; Makoto Tada; Yutaro Koike; Tomohiro Miyoshi; Kenta Tane; Keiju Aokage; Masahiro Tsuboi
Annals of surgical oncology, Jun. 2024
Lead

Clinicopathological differences between EGFR mutated and EGFR wild-type lung adenocarcinoma with papillary predominant pattern.
Eisuke Goto; Tetsuro Taki; Kotaro Nomura; Yuko Miyakami; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Keiju Aokage; Michiko Nagamine; Shingo Sakashita; Naoya Sakamoto; Motohiro Kojima; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 192, 107830-107830, Jun. 2024
Lead

The significance of regular chest computed tomography in postoperative surveillance for surgically resected non-small cell lung cancer based on TNM 8th staging system.
Jun Suzuki; Tomohiro Miyoshi; Kenta Tane; Ken Onodera; Yutaro Koike; Takashi Sakai; Joji Samejima; Keiju Aokage; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 72(5), 346-354, May 2024
Lead

Ten-year follow-up outcomes of limited resection trial for radiologically less-invasive lung cancer.
Takahiro Niimi; Joji Samejima; Masashi Wakabayashi; Tomohiro Miyoshi; Kenta Tane; Keiju Aokage; Tetsuro Taki; Tokiko Nakai; Genichiro Ishii; Akitomo Kikuchi; Emi Yoshioka; Tomoyuki Yokose; Hiroyuki Ito; Masahiro Tsuboi
Japanese journal of clinical oncology, 54(4), 479-488, Apr. 2024
Lead

Predictors of residual simultaneous multiple ground-glass nodule progression after dominant lesion resection.
Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Keiju Aokage; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 72(3), 183-191, Mar. 2024
Lead

EGFR mutation impacts recurrence in high-risk early-stage lung adenocarcinoma in the IASLC grading system.
Kotaro Nomura; Keiju Aokage; Yasunori Kaminuma; Tokiko Nakai; Masashi Wakabayashi; Takashi Ikeno; Yutaro Koike; Tetsuro Taki; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Genichiro Ishii; Masahiro Tsuboi
International journal of clinical oncology, 29(3), 248-257, Mar. 2024
Lead

Rare but clinically important salivary gland-type tumor of the lung: A review.
Shinkichi Takamori; Yasushi Yatabe; Atsushi Osoegawa; Keiju Aokage; Hiroshige Yoshioka; Tomohiro Miyoshi; Takahiro Mimae; Makoto Endo; Aritoshi Hattori; Masaya Yotsukura; Tetsuya Isaka; Mitsuhiro Isaka; Tomohiro Maniwa; Ryu Nakajima; Shun-Ichi Watanabe
Japanese journal of clinical oncology, 54(2), 121-128, Feb. 2024
Lead

Aorta and main pulmonary artery segmentation using stacked U-Net and localization on non-contrast-enhanced computed tomography images.
Hidenobu Suzuki; Yoshiki Kawata; Keiju Aokage; Yuji Matsumoto; Toshihiko Sugiura; Nobuhiro Tanabe; Yasutaka Nakano; Takaaki Tsuchida; Masahiko Kusumoto; Kazuyoshi Marumo; Masahiro Kaneko; Noboru Niki
Medical physics, 51(2), 1232-1243, Feb. 2024
Lead

Prognostic value of predominant subtype in pathological stage II-III lung adenocarcinoma with epidermal growth factor receptor mutation.
Shingo Kitagawa; Yoshitaka Zenke; Tetsuro Taki; Keiju Aokage; Tetsuya Sakai; Yuji Shibata; Hiroki Izumi; Kaname Nosaki; Shigeki Umemura; Shingo Matsumoto; Kiyotaka Yoh; Naoya Sakamoto; Shingo Sakashita; Motohiro Kojima; Masahiro Tsuboi; Koichi Goto; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 188, 107453-107453, Feb. 2024
Lead

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer with radiologically pure-solid appearance in Japan (JCOG0802/WJOG4607L): a post-hoc supplemental analysis of a multicentre, open-label, phase 3 trial.
Aritoshi Hattori; Kenji Suzuki; Kazuya Takamochi; Masashi Wakabayashi; Yuta Sekino; Yasuhiro Tsutani; Ryu Nakajima; Keiju Aokage; Hisashi Saji; Masahiro Tsuboi; Morihito Okada; Hisao Asamura; Kenichi Nakamura; Haruhiko Fukuda; Shun-Ichi Watanabe
The Lancet. Respiratory medicine, 12(2), 105-116, Feb. 2024
Lead

Prognostic impact of adjuvant therapy for cisplatin-unfit patients with non-small-cell lung cancer: A multicenter analysis.
Osamu Noritake; Shota Nakamura; Fumie Kinoshita; Keiju Aokage; Tetsuhiko Asao; Yosuke Matsuura; Toyofumi Fengshi Chen-Yoshikawa
Lung cancer (Amsterdam, Netherlands), 188, 107470-107470, Feb. 2024
Lead

An accurate prediction of negative lymph node metastasis with consideration of glucose metabolism in early-stage non-small cell lung cancer.
Ken Onodera; Keiju Aokage; Masashi Wakabayashi; Takashi Ikeno; Takahiro Morita; Shuhei Ohashi; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 72(1), 24-30, Jan. 2024
Lead

Risk Factors of Severe Postoperative Complication in Lung Cancer Patients with Diabetes Mellitus.
Yutaro Koike; Keiju Aokage; Keiichiro Osame; Masashi Wakabayashi; Tomohiro Miyoshi; Kenji Suzuki; Masahiro Tsuboi
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 30(1), 2024
Lead

Risk factors for loss of pulmonary function after wedge resection for peripheral ground-glass opacity dominant lung cancer.
Tomohiro Miyoshi; Hiroyuki Ito; Masashi Wakabayashi; Tadayoshi Hashimoto; Yuta Sekino; Kenji Suzuki; Masahiro Tsuboi; Yasumitsu Moriya; Ichiro Yoshino; Tetsuya Isaka; Aritoshi Hattori; Takahiro Mimae; Mitsuhiro Isaka; Tomohiro Maniwa; Makoto Endo; Hiroshige Yoshioka; Kazuo Nakagawa; Ryu Nakajima; Yasuhiro Tsutani; Hisashi Saji; Morihito Okada; Keiju Aokage; Haruhiko Fukuda; Shun-Ichi Watanabe
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 64(6), Dec. 2023
Lead

The prognostic impact of a high number of peritumoral alveolar macrophages in neuroendocrine carcinoma in the lung.
Takehiko Tanaka; Shigeki Umemura; Tomohiro Miyoshi; Tokiko Nakai; Osamu Noritake; Jun Suzuki; Kenta Tane; Joji Samejima; Keiju Aokage; Sachiyo Mimaki; Katsuya Tsuchihara; Tetsuro Taki; Saori Miyazaki; Reiko Watanabe; Shingo Sakashita; Naoya Sakamoto; Motohiro Kojima; Koichi Goto; Norihiko Ikeda; Masahiro Tsuboi; Genichiro Ishii
Pathology international, 73(10), 497-508, Oct. 2023
Lead

Long-term outcome of patients with peripheral ground-glass opacity-dominant lung cancer after sublobar resections.
Ichiro Yoshino; Yasumitsu Moriya; Kenji Suzuki; Masashi Wakabayashi; Hisashi Saji; Keiju Aokage; Makoto Suzuki; Hiroyuki Ito; Isao Matsumoto; Masashi Kobayashi; Tatsuro Okamoto; Morihito Okada; Motohiro Yamashita; Norihiko Ikeda; Shinichiro Nakamura; Tomoko Kataoka; Masahiro Tsuboi; Shun-Ichi Watanabe
The Journal of thoracic and cardiovascular surgery, 166(4), 1222-1231, Oct. 2023
Lead

Sublobar Resection for Non-Small Cell Lung Cancer in Octogenarians: A Prospective, Multicenter Study.
Takahiro Mimae; Hisashi Saji; Hiroshige Nakamura; Norihito Okumura; Masanori Tsuchida; Makoto Sonobe; Takuro Miyazaki; Keiju Aokage; Masayuki Nakao; Tomohiro Haruki; Morihito Okada; Kenji Suzuki; Ichiro Yoshino
The Annals of thoracic surgery, 116(3), 543-551, Sep. 2023
Lead

Efficacy of Preoperative Biopsy in Predicting the Newly Proposed Histologic Grade of Resected Lung Adenocarcinoma.
Seiyu Jeong-Yoo Ohtani-Kim; Tetsuro Taki; Kenta Tane; Tomohiro Miyoshi; Joji Samejima; Keiju Aokage; Yusuke Nagasaki; Motohiro Kojima; Shingo Sakashita; Reiko Watanabe; Naoya Sakamoto; Koichi Goto; Masahiro Tsuboi; Genichiro Ishii
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 36(9), 100209-100209, Sep. 2023
Lead

Segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less including ground-glass opacity (JCOG1211): a multicentre, single-arm, confirmatory, phase 3 trial.
Keiju Aokage; Kenji Suzuki; Hisashi Saji; Masashi Wakabayashi; Tomoko Kataoka; Yuta Sekino; Haruhiko Fukuda; Makoto Endo; Aritoshi Hattori; Takahiro Mimae; Tomohiro Miyoshi; Mitsuhiro Isaka; Hiroshige Yoshioka; Ryu Nakajima; Kazuo Nakagawa; Jiro Okami; Hiroyuki Ito; Hiroaki Kuroda; Masahiro Tsuboi; Norihito Okumura; Makoto Takahama; Yasuhisa Ohde; Tadashi Aoki; Yasuhiro Tsutani; Morihito Okada; Shun-Ichi Watanabe
The Lancet. Respiratory medicine, 11(6), 540-549, Jun. 2023
Lead

Asia expert consensus on segmentectomy in non-small cell lung cancer: A modified Delphi study.
Lunxu Liu; Keiju Aokage; Chang Chen; Chun Chen; Liang Chen; Yong-Hee Kim; Chang Young Lee; Chengwu Liu; Chia-Chuan Liu; Wataru Nishio; Kenji Suzuki; Lijie Tan; Yau-Lin Tseng; Masaya Yotsukura; Shun-Ichi Watanabe
JTCVS open, 14, 483-501, Jun. 2023
Lead

Clinicopathological features and prognostic impact of dirty necrosis in metastatic lung cancers from the colon and rectum.
Yasuhito Konishi; Tetsuro Taki; Tokiko Nakai; Takashi Kuroe; Ryo Morisue; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Keiju Aokage; Saori Miyazaki; Naoya Sakamoto; Shingo Sakashita; Reiko Watanabe; Motohiro Kojima; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Cancer science, 114(5), 2169-2177, May 2023
Lead

Long-term survival outcomes after lobe-specific nodal dissection in patients with early non-small-cell lung cancer.
Atsushi Kamigaichi; Keiju Aokage; Takashi Ikeno; Masashi Wakabayashi; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Masahiro Tsuboi
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 63(2), Feb. 2023
Lead

Comparison of various lung intersegmental plane identification methods.
Ken Onodera; Jun Suzuki; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Keiju Aokage; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 71(2), 90-97, Feb. 2023
Lead

Tumor size exceeding 5 cm as a valid prognostic factor in all stages of thymic epithelial tumors.
Takashi Sakai; Keiju Aokage; Tomohiro Miyoshi; Kenta Tane; Genichiro Ishii; Koichi Goto; Masahiro Tsuboi
Surgery today, 53(1), 42-50, Jan. 2023
Lead

Correction to: Tumor size exceeding 5 cm as a valid prognostic factor in all stages of thymic epithelial tumors.
Takashi Sakai; Keiju Aokage; Tomohiro Miyoshi; Kenta Tane; Genichiro Ishii; Koichi Goto; Masahiro Tsuboi
Surgery today, 53(1), 51-51, Jan. 2023
Lead

Real-world perioperative outcomes of segmentectomy versus lobectomy for early-stage lung cancer: a propensity score-matched analysis.
Junji Ichinose; Hiroyuki Yamamoto; Keiju Aokage; Haruhiko Kondo; Yukio Sato; Kenji Suzuki; Masayuki Chida
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 63(1), Dec. 2022
Lead

Prognostic impact of the number of peri-tumoral alveolar macrophages in patients with stage I lung adenocarcinoma.
Osamu Noritake; Keiju Aokage; Ayako Suzuki; Kenta Tane; Tomohiro Miyoshi; Joji Samejima; Toyohumi Yoshikawa; Shawhay Charles Murata; Tokiko Nakai; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 148(12), 3437-3447, Dec. 2022
Lead

BATF epigenetically and transcriptionally controls the activation program of regulatory T cells in human tumors.
Kota Itahashi; Takuma Irie; Junichiro Yuda; Shogo Kumagai; Tokiyoshi Tanegashima; Yi-Tzu Lin; Sho Watanabe; Yasushi Goto; Jun Suzuki; Keiju Aokage; Masahiro Tsuboi; Yosuke Minami; Genichiro Ishii; Yuichiro Ohe; Wataru Ise; Tomohiro Kurosaki; Yutaka Suzuki; Shohei Koyama; Hiroyoshi Nishikawa
Science immunology, 7(76), eabk0957, Oct. 2022
Lead

The C-reactive protein to albumin ratio is a prognostic factor for stage I non-small cell lung cancer in elderly patients: JACS1303.
Takuro Miyazaki; Hisashi Saji; Hiroshige Nakamura; Takeshi Nagayasu; Norihito Okumura; Masanori Tsuchida; Makoto Sonobe; Keiju Aokage; Masayuki Nakao; Tomohiro Haruki; Morihito Okada; Kenji Suzuki; Masayuki Chida; Ichiro Yoshino
Surgery today, 52(10), 1463-1471, Oct. 2022
Lead

Prognostic impact of examined mediastinal lymph node count in clinical N0 non-small cell lung cancer.
Atsushi Kamigaichi; Keiju Aokage; Shinya Katsumata; Genichiro Ishii; Masashi Wakabayashi; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Masahiro Tsuboi
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 62(2), Jul. 2022
Lead

Prognostic Impact of Mediastinal Lymph Node Dissection in Octogenarians With Lung Cancer: JACS1303.
Masayuki Nakao; Hisashi Saji; Mingoyn Mun; Hiroshige Nakamura; Norihito Okumura; Masanori Tsuchida; Makoto Sonobe; Takuro Miyazaki; Keiju Aokage; Tomohiro Haruki; Morihito Okada; Kenji Suzuki; Masayuki Chida
Clinical lung cancer, 23(3), e176-e184, May 2022
Lead

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial.
Hisashi Saji; Morihito Okada; Masahiro Tsuboi; Ryu Nakajima; Kenji Suzuki; Keiju Aokage; Tadashi Aoki; Jiro Okami; Ichiro Yoshino; Hiroyuki Ito; Norihito Okumura; Masafumi Yamaguchi; Norihiko Ikeda; Masashi Wakabayashi; Kenichi Nakamura; Haruhiko Fukuda; Shinichiro Nakamura; Tetsuya Mitsudomi; Shun-Ichi Watanabe; Hisao Asamura
Lancet (London, England), 399(10335), 1607-1617, Apr. 2022
Lead

Study protocol for JCOG1807C (DEEP OCEAN): a interventional prospective trial to evaluate the efficacy and safety of durvalumab before and after operation or durvalumab as maintenance therapy after chemoradiotherapy against superior sulcus non-small cell lung cancer.
Keiju Aokage; Masahiro Tsuboi; Yoshitaka Zenke; Hidehito Horinouchi; Naoki Nakamura; Satoshi Ishikura; Hiroyoshi Nishikawa; Shogo Kumagai; Shohei Koyama; Keisuke Kanato; Tomoko Kataoka; Masashi Wakabayashi; Miki Fukutani; Haruhiko Fukuda; Yuichiro Ohe; Shun-Ichi Watanabe
Japanese journal of clinical oncology, 52(4), 383-387, Apr. 2022
Lead

18F-fluorodeoxyglucose uptake in PET is associated with the tumor microenvironment in metastatic lymph nodes and prognosis in N2 lung adenocarcinoma.
Kotaro Nomura; Tokiko Nakai; Yukino Nishina; Naoya Sakamoto; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Keiju Aokage; Motohiro Kojima; Shingo Sakashita; Tetsuro Taki; Saori Miyazaki; Reiko Watanabe; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Cancer science, 113(4), 1488-1496, Apr. 2022
Lead

Prognostic impact of count of extratumoral lymphatic permeation in lung adenocarcinoma and its relation to the immune microenvironment.
Takahiro Niimi; Tokiko Nakai; Keiju Aokage; Kenta Tane; Tomohiro Miyoshi; Joji Samejima; Saori Miyazaki; Tetsuro Taki; Naoya Sakamoto; Shingo Sakashita; Reiko Watanabe; Motohiro Kojima; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Cancer science, 113(4), 1497-1506, Apr. 2022
Lead

Lung Cancer in Japan.
Hidehito Horinouchi; Masahiko Kusumoto; Yasushi Yatabe; Keiju Aokage; Shun-Ichi Watanabe; Satoshi Ishikura
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 17(3), 353-361, Mar. 2022
Lead

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments.
Shogo Kumagai; Shohei Koyama; Kota Itahashi; Tokiyoshi Tanegashima; Yi-Tzu Lin; Yosuke Togashi; Takahiro Kamada; Takuma Irie; Genki Okumura; Hidetoshi Kono; Daisuke Ito; Rika Fujii; Sho Watanabe; Atsuo Sai; Shota Fukuoka; Eri Sugiyama; Go Watanabe; Takuya Owari; Hitomi Nishinakamura; Daisuke Sugiyama; Yuka Maeda; Akihito Kawazoe; Hiroki Yukami; Keigo Chida; Yuuki Ohara; Tatsuya Yoshida; Yuki Shinno; Yuki Takeyasu; Masayuki Shirasawa; Kenta Nakama; Keiju Aokage; Jun Suzuki; Genichiro Ishii; Takeshi Kuwata; Naoya Sakamoto; Masahito Kawazu; Toshihide Ueno; Taisuke Mori; Naoya Yamazaki; Masahiro Tsuboi; Yasushi Yatabe; Takahiro Kinoshita; Toshihiko Doi; Kohei Shitara; Hiroyuki Mano; Hiroyoshi Nishikawa
Cancer cell, 40(2), 201-218, Feb. 2022
Lead

A single-arm study of sublobar resection for ground-glass opacity dominant peripheral lung cancer.
Kenji Suzuki; Shun-Ichi Watanabe; Masashi Wakabayashi; Hisashi Saji; Keiju Aokage; Yasumitsu Moriya; Ichiro Yoshino; Masahiro Tsuboi; Shinichiro Nakamura; Kenichi Nakamura; Tetsuya Mitsudomi; Hisao Asamura
The Journal of thoracic and cardiovascular surgery, 163(1), 289-301, Jan. 2022
Lead

Lymph node metastasis and predictive factors in clinical stage IA squamous cell carcinoma of the lung based on radiological findings.
Kenta Tane; Tomohiro Miyoshi; Joji Samejima; Keiju Aokage; Genichiro Ishii; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 70(1), 52-58, Jan. 2022
Lead

Prognostic impact of extranodal extension in patients with pN1-N2 lung adenocarcinoma.
Kotaro Nomura; Keiju Aokage; Tokiko Nakai; Shingo Sakashita; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 147(12), 3699-3707, Dec. 2021
Lead

Mediastinal lymph node dissection for the elderly with clinical stage I non-small cell lung cancer.
Shinya Katsumata; Kenta Tane; Jun Suzuki; Tomohiro Miyoshi; Joji Samejima; Keiju Aokage; Genichiro Ishii; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 69(12), 1560-1566, Dec. 2021
Lead

Highly immunogenic cancer cells require activation of the WNT pathway for immunological escape.
Yoshiko Takeuchi; Tokiyoshi Tanegashima; Eiichi Sato; Takuma Irie; Atsuo Sai; Kota Itahashi; Shogo Kumagai; Yasuko Tada; Yosuke Togashi; Shohei Koyama; Esra A Akbay; Takahiro Karasaki; Keisuke Kataoka; Soichiro Funaki; Yasushi Shintani; Izumi Nagatomo; Hiroshi Kida; Genichiro Ishii; Tomohiro Miyoshi; Keiju Aokage; Kazuhiro Kakimi; Seishi Ogawa; Meinoshin Okumura; Masatoshi Eto; Atsushi Kumanogoh; Masahiro Tsuboi; Hiroyoshi Nishikawa
Science immunology, 6(65), eabc6424, Nov. 2021
Lead

Survival of Octogenarians with Early-Stage Non-small Cell Lung Cancer is Comparable Between Wedge Resection and Lobectomy/Segmentectomy: JACS1303.
Takahiro Mimae; Hisashi Saji; Hiroshige Nakamura; Norihito Okumura; Masanori Tsuchida; Makoto Sonobe; Takuro Miyazaki; Keiju Aokage; Masayuki Nakao; Tomohiro Haruki; Morihito Okada; Kenji Suzuki; Masayuki Chida
Annals of surgical oncology, 28(12), 7219-7227, Nov. 2021
Lead

Prognostic influence of epidermal growth factor receptor mutation and radiological ground glass appearance in patients with early-stage lung adenocarcinoma.
Keiju Aokage; Tomohiro Miyoshi; Masashi Wakabayashi; Takashi Ikeno; Jun Suzuki; Kenta Tane; Joji Samejima; Masahiro Tsuboi
Lung cancer (Amsterdam, Netherlands), 160, 8-16, Oct. 2021
Lead

Clinicopathological, gene expression and genetic features of stage I lung adenocarcinoma with necrosis.
Hiroaki Oiwa; Keiju Aokage; Ayako Suzuki; Kei Sato; Takashi Kuroe; Sachiyo Mimaki; Kenta Tane; Tomohiro Miyoshi; Joji Samejima; Katsuya Tsuchihara; Koichi Goto; Kazuhito Funai; Masahiro Tsuboi; Tokiko Nakai; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 159, 74-83, Sep. 2021
Lead

Prospective evaluation of watchful waiting for early-stage lung cancer with ground-glass opacity: a single-arm confirmatory multicenter study: Japan Clinical Oncology Group study JCOG1906 (EVERGREEN study).
Tomohiro Miyoshi; Keiju Aokage; Masashi Wakabayashi; Ryo Shimoyama; Tomoko Kataoka; Haruhiko Fukuda; Shun-Ichi Watanabe
Japanese journal of clinical oncology, 51(8), 1330-1333, Aug. 2021
Lead

Correlation between the number of viable tumor cells and immune cells in the tumor microenvironment in non-small cell lung cancer after induction therapy.
Hironobu Hoshino; Keiju Aokage; Tomohiro Miyoshi; Kenta Tane; Motohiro Kojima; Masato Sugano; Takeshi Kuwata; Atsushi Ochiai; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Pathology international, 71(8), 512-520, Aug. 2021
Lead

Predicting pathological lymph node status in clinical stage IA peripheral lung adenocarcinoma.
Keiju Aokage; Kenji Suzuki; Masashi Wakabayashi; Tomonori Mizutani; Aritoshi Hattori; Haruhiko Fukuda; Shun-Ichi Watanabe
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 60(1), 64-71, Jul. 2021
Lead

Pathological features and prognostic implications of ground-glass opacity components on computed tomography for clinical stage I lung adenocarcinoma.
Shinya Katsumata; Keiju Aokage; Genichiro Ishii; Hironobu Hoshino; Jun Suzuki; Tomohiro Miyoshi; Kenta Tane; Joji Samejima; Masahiro Tsuboi
Surgery today, 51(7), 1188-1202, Jul. 2021
Lead

Continuation of aspirin perioperatively for lung resection: a propensity matched analysis.
Takashi Sakai; Keiju Aokage; Shinya Katsumata; Kenta Tane; Tomohiro Miyoshi; Masahiro Tsuboi
Surgery today, 51(6), 1054-1060, Jun. 2021
Lead

Prognostic impact of home oxygen therapy on patients with resected non-small-cell lung cancer with interstitial lung disease.
Keigo Sekihara; Keiju Aokage; Takashi Hiyama; Hiroaki Oiwa; Tomohiro Miyoshi; Kenta Tane; Genichiro Ishii; Masahiro Tsuboi
Surgery today, 51(6), 1036-1043, Jun. 2021
Lead

Prognostic impact of a ground-glass opacity component in clinical stage IA non-small cell lung cancer.
Aritoshi Hattori; Kenji Suzuki; Kazuya Takamochi; Masashi Wakabayashi; Keiju Aokage; Hisashi Saji; Shun-Ichi Watanabe
The Journal of thoracic and cardiovascular surgery, 161(4), 1469-1480, Apr. 2021
Lead

Surgical challenges in multimodal treatment of N2-stage IIIA non-small cell lung cancer.
Masafumi Yamaguchi; Kazuo Nakagawa; Kenji Suzuki; Kazuya Takamochi; Hiroyuki Ito; Jiro Okami; Keiju Aokage; Satoshi Shiono; Hiroshige Yoshioka; Tadashi Aoki; Yasuhiro Tsutani; Morihito Okada; Shun-Ichi Watanabe
Japanese journal of clinical oncology, 51(3), 333-344, Mar. 2021
Lead

Relationship between podoplanin-expressing cancer-associated fibroblasts and the immune microenvironment of early lung squamous cell carcinoma.
Jun Suzuki; Keiju Aokage; Shinya Neri; Takashi Sakai; Hiroko Hashimoto; Yinghan Su; Shota Yamazaki; Hiroshi Nakamura; Kenta Tane; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 153, 1-10, Mar. 2021
Lead

Prognostic impact of the tumor immune microenvironment in pulmonary pleomorphic carcinoma.
Ryosuke Amemiya; Tomohiro Miyoshi; Keiju Aokage; Jun Suzuki; Hironobu Hoshino; Hibiki Udagawa; Kenta Tane; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Koichi Goto; Norihiko Ikeda; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 153, 56-65, Mar. 2021
Lead

Recent advances and future perspectives in adjuvant and neoadjuvant immunotherapies for lung cancer.
Masaya Yotsukura; Kazuo Nakagawa; Kenji Suzuki; Kazuya Takamochi; Hiroyuki Ito; Jiro Okami; Keiju Aokage; Satoshi Shiono; Hiroshige Yoshioka; Tadashi Aoki; Yasuhiro Tsutani; Morihito Okada; Shun-Ichi Watanabe
Japanese journal of clinical oncology, 51(1), 28-36, Jan. 2021
Lead

Japanese Lung Cancer Society Guidelines for Stage IV NSCLC With EGFR Mutations.
Kiichiro Ninomiya; Shunsuke Teraoka; Yoshitaka Zenke; Hirotsugu Kenmotsu; Yukiko Nakamura; Yusuke Okuma; Akihiro Tamiya; Kaname Nosaki; Masahiro Morise; Keiju Aokage; Yuko Oya; Toshiyuki Kozuki; Tomohiro Sakamoto; Kentaro Tanaka; Hisashi Tanaka; Junko Tanizaki; Satoru Miura; Hideaki Mizutani; Eisaku Miyauchi; Ou Yamaguchi; Noriyuki Ebi; Yasushi Goto; Takaaki Sasaki; Haruko Daga; Satoshi Morita; Takeharu Yamanaka; Shinsuke Amano; Kazuo Hasegawa; Chiyo K Imamura; Kenichi Suzuki; Kazuko Nakajima; Hitomi Nishimoto; Satoshi Oizumi; Toyoaki Hida; Katsuyuki Hotta; Yuichi Takiguchi
JTO clinical and research reports, 2(1), 100107-100107, Jan. 2021
Lead

Randomized Phase III Study of Irinotecan Plus Cisplatin Versus Etoposide Plus Cisplatin for Completely Resected High-Grade Neuroendocrine Carcinoma of the Lung: JCOG1205/1206.
Hirotsugu Kenmotsu; Seiji Niho; Masahiro Tsuboi; Masashi Wakabayashi; Genichiro Ishii; Kazuo Nakagawa; Haruko Daga; Hiroshi Tanaka; Haruhiro Saito; Keiju Aokage; Toshiaki Takahashi; Toshi Menju; Takashi Kasai; Ichiro Yoshino; Koichi Minato; Morihito Okada; Junko Eba; Hisao Asamura; Yuichiro Ohe; Shun-Ichi Watanabe
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 38(36), 4292-4301, Dec. 2020
Lead

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies.
Shogo Kumagai; Yosuke Togashi; Takahiro Kamada; Eri Sugiyama; Hitomi Nishinakamura; Yoshiko Takeuchi; Kochin Vitaly; Kota Itahashi; Yuka Maeda; Shigeyuki Matsui; Takuma Shibahara; Yasuho Yamashita; Takuma Irie; Ayaka Tsuge; Shota Fukuoka; Akihito Kawazoe; Hibiki Udagawa; Keisuke Kirita; Keiju Aokage; Genichiro Ishii; Takeshi Kuwata; Kenta Nakama; Masahito Kawazu; Toshihide Ueno; Naoya Yamazaki; Koichi Goto; Masahiro Tsuboi; Hiroyuki Mano; Toshihiko Doi; Kohei Shitara; Hiroyoshi Nishikawa
Nature immunology, 21(11), 1346-1358, Nov. 2020
Lead

Continuing surgical education of non-technical skills.
Masaomi Yamane; Seiichiro Sugimoto; Etsuji Suzuki; Keiju Aokage; Mikio Okazaki; Junichi Soh; Makio Hayama; Yuji Hirami; Takashi Yorifuji; Shinichi Toyooka
Annals of medicine and surgery (2012), 58, 177-186, Oct. 2020
Lead

Sublobar resection versus lobectomy for patients with resectable stage I non-small cell lung cancer with idiopathic pulmonary fibrosis: a phase III study evaluating survival (JCOG1708, SURPRISE).
Kiyo Tanaka; Yasuhiro Tsutani; Masashi Wakabayashi; Tomonori Mizutani; Keiju Aokage; Yoshihiro Miyata; Hiroaki Kuroda; Hisashi Saji; Shun-Ichi Watanabe; Morihito Okada
Japanese journal of clinical oncology, 50(9), 1076-1079, Sep. 2020
Lead

Association between the mutational smoking signature and the immune microenvironment in lung adenocarcinoma.
Kei Sato; Sachiyo Mimaki; Riu Yamashita; Yosuke Togashi; Tomoyuki Naito; Hibiki Udagawa; Shinya Katsumata; Shoko Nakasone; Tomohiro Miyoshi; Kenta Tane; Keiju Aokage; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Koichi Goto; Masahiro Tsuboi; Katsuya Tsuchihara; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 147, 12-20, Sep. 2020
Lead

Machine learning-based histological classification that predicts recurrence of peripheral lung squamous cell carcinoma.
Yutaro Koike; Keiju Aokage; Kosuke Ikeda; Tokiko Nakai; Kenta Tane; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Toshiyuki Tanaka; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 147, 252-258, Sep. 2020
Lead

Perioperative pirfenidone treatment as prophylaxis against acute exacerbation of idiopathic pulmonary fibrosis: a single-center analysis.
Keigo Sekihara; Keiju Aokage; Tomohiro Miyoshi; Kenta Tane; Genichiro Ishii; Masahiro Tsuboi
Surgery today, 50(8), 905-911, Aug. 2020
Lead

Delayed cut-end recurrence after wedge resection for pulmonary ground-glass opacity adenocarcinoma despite negative surgical margin.
Keigo Sekihara; Junji Yoshida; Makoto Oda; Tomonari Oki; Takuya Ueda; Takuya Ito; Tomohiro Miyoshi; Keiju Aokage; Kenta Tane; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 68(6), 644-648, Jun. 2020
Lead

Optimal method for measuring invasive size that predicts survival in invasive mucinous adenocarcinoma of the lung.
Tomonari Oki; Keiju Aokage; Shogo Nomura; Kenta Tane; Tomohiro Miyoshi; Norihiko Shiiya; Kazuhito Funai; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 146(5), 1291-1298, May 2020
Lead

Long-term survival outcome after lobectomy in patients with clinical T1 N0 lung cancer.
Hiroyuki Ito; Kenji Suzuki; Tomonori Mizutani; Keiju Aokage; Masashi Wakabayashi; Haruhiko Fukuda; Shun-Ichi Watanabe
The Journal of thoracic and cardiovascular surgery, Jan. 2020
Lead

High-Risk Factors for Recurrence of Stage I Lung Adenocarcinoma: Follow-up Data From JCOG0201.
Yasuhiro Tsutani; Kenji Suzuki; Teruaki Koike; Masashi Wakabayashi; Tomonori Mizutani; Keiju Aokage; Hisashi Saji; Kazuo Nakagawa; Yoshitaka Zenke; Kazuya Takamochi; Hiroyuki Ito; Tadashi Aoki; Jiro Okami; Hiroshige Yoshioka; Morihito Okada; Shun-Ichi Watanabe
The Annals of thoracic surgery, 108(5), 1484-1490, Nov. 2019
Lead

Correlation between maximum standardized uptake values on FDG-PET and microenvironmental factors in patients with clinical stage IA radiologic pure-solid lung adenocarcinoma.
Tomohiro Ichikawa; Keiju Aokage; Tomohiro Miyoshi; Kenta Tane; Kenji Suzuki; Hideki Makinoshima; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 136, 57-64, Oct. 2019
Lead

Comparison of pulmonary segmentectomy and lobectomy: Safety results of a randomized trial.
Kenji Suzuki; Hisashi Saji; Keiju Aokage; Shun-Ichi Watanabe; Morihito Okada; Junki Mizusawa; Ryu Nakajima; Masahiro Tsuboi; Shinichiro Nakamura; Kenichi Nakamura; Tetsuya Mitsudomi; Hisao Asamura
The Journal of thoracic and cardiovascular surgery, 158(3), 895-907, Sep. 2019
Lead

Proportion of goblet cell is associated with malignant potential in invasive mucinous adenocarcinoma of the lung.
Tomonari Oki; Keiju Aokage; Takuya Ueda; Masato Sugano; Kenta Tane; Tomohiro Miyoshi; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Kazuhito Funai; Masahiro Tsuboi; Genichiro Ishii
Pathology international, 69(9), 526-535, Sep. 2019
Lead

Prediction of prolonged air leak after lung resection using continuous log data of flow by digital drainage system.
Masaki Goto; Keiju Aokage; Keigo Sekihara; Tomohiro Miyoshi; Kenta Tane; Kohei Yokoi; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 67(8), 684-689, Aug. 2019
Lead

Prognostic Impact of the Number of Metastatic Lymph Nodes on the Eighth Edition of the TNM Classification of NSCLC.
Shinya Katsumata; Keiju Aokage; Genichiro Ishii; Shoko Nakasone; Takashi Sakai; Satoshi Okada; Tomohiro Miyoshi; Kenta Tane; Masahiro Tsuboi
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 14(8), 1408-1418, Aug. 2019
Lead

Ground-Glass Opacity Is a Strong Prognosticator for Pathologic Stage IA Lung Adenocarcinoma.
Tomohiro Miyoshi; Keiju Aokage; Shinya Katsumata; Kenta Tane; Genichiro Ishii; Masahiro Tsuboi
The Annals of thoracic surgery, 108(1), 249-255, Jul. 2019
Lead

Growth patterns of small peripheral squamous cell carcinoma of the lung and their impacts on pathological and biological characteristics of tumor cells.
Tomokazu Omori; Keiju Aokage; Hiroshi Nakamura; Shinya Katsumata; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Norihiko Ikeda; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 145(7), 1773-1783, Jul. 2019
Lead

Large pulmonary sclerosing pneumocytoma with massive necrosis and vascular invasion: a case report.
Takashi Sakai; Tomohiro Miyoshi; Shigeki Umemura; Jun Suzuki; Shoko Nakasone; Satoshi Okada; Kenta Tane; Keiju Aokage; Koichi Goto; Noriko Motoi; Genichiro Ishii; Masahiro Tsuboi
Oxford medical case reports, 2019(7), Jul. 2019
Lead

Survival and prognostic factors after pulmonary metastasectomy of head and neck cancer: what are the clinically informative prognostic indicators?
Tomonari Oki; Tomoyuki Hishida; Junji Yoshida; Masaki Goto; Keigo Sekihara; Tomohiro Miyoshi; Keiju Aokage; Genichiro Ishii; Masahiro Tsuboi
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 55(5), 942-947, May 2019
Lead

Clinicopathological characteristics associated with necrosis in pulmonary metastases from colorectal cancer.
Jun Suzuki; Motohiro Kojima; Keiju Aokage; Takashi Sakai; Hiroshi Nakamura; Yuuki Ohara; Kenta Tane; Tomohiro Miyoshi; Masato Sugano; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Masaaki Ito; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Virchows Archiv : an international journal of pathology, 474(5), 569-575, May 2019
Lead

Radiologic Criteria in Predicting Pathologic Less Invasive Lung Cancer According to TNM 8th Edition.
Shinya Katsumata; Keiju Aokage; Shoko Nakasone; Takashi Sakai; Satoshi Okada; Tomohiro Miyoshi; Kenta Tane; Ryuichi Hayashi; Genichiro Ishii; Masahiro Tsuboi
Clinical lung cancer, 20(2), e163-e170, Mar. 2019
Lead

Stapling cartridge lavage cytology in limited resection for pulmonary malignant tumors: assessment of cytological status of the surgical margin.
Tomohiro Miyoshi; Junji Yoshida; Keiju Aokage; Kenta Tane; Genichiro Ishii; Masahiro Tsuboi
Heliyon, 5(2), e01240, Feb. 2019
Lead

Clinical prediction of solitary pulmonary nodule after a curative resection for gastric cancer.
Risa Kanai; Kenta Tane; Genichiro Ishii; Jun Suzuki; Takashi Sakai; Satoshi Okada; Tomohiro Miyoshi; Keiju Aokage; Masahiro Tsuboi
Japanese journal of clinical oncology, 48(12), 1083-1087, Dec. 2018
Lead

Characterization of the tumor immune-microenvironment of lung adenocarcinoma associated with usual interstitial pneumonia.
Takuya Ueda; Keiju Aokage; Sachiyo Mimaki; Kenta Tane; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Masahiko Kusumoto; Kenji Suzuki; Katsuya Tsuchihara; Hiroyoshi Nishikawa; Koichi Goto; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 126, 162-169, Dec. 2018
Lead

Link between tumor-promoting fibrous microenvironment and an immunosuppressive microenvironment in stage I lung adenocarcinoma.
Takashi Sakai; Keiju Aokage; Shinya Neri; Hiroshi Nakamura; Shogo Nomura; Kenta Tane; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Akira Iyoda; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 126, 64-71, Dec. 2018
Lead

Extended bronchoplasty for locally advanced left lower lobe lung cancer: surgical technique and outcomes.
Tomoyuki Hishida; Keiju Aokage; Junji Yoshida; Tomohiro Miyoshi; Masahiro Tsuboi
Interactive cardiovascular and thoracic surgery, 27(4), 602-605, Oct. 2018
Lead

Differences of tumor microenvironment between stage I lepidic-positive and lepidic-negative lung adenocarcinomas.
Shinya Katsumata; Keiju Aokage; Tomohiro Miyoshi; Kenta Tane; Hiroshi Nakamura; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Ryuichi Hayashi; Masahiro Tsuboi; Genichiro Ishii
The Journal of thoracic and cardiovascular surgery, 156(4), 1679-1688, Oct. 2018
Lead

Utility of Site-Specific Biopsy for Diagnosis of Desmoplastic Malignant Mesothelioma.
Takashi Sakai; Kenta Tane; Yuko Usui; Tomohiro Miyoshi; Shingo Matsumoto; Keiju Aokage; Koichi Goto; Masayuki Suzuki; Genichiro Ishii; Masahiro Tsuboi
The Annals of thoracic surgery, 106(3), e125-e128, Sep. 2018
Lead

Immunosuppressive tumor microenvironment of usual interstitial pneumonia-associated squamous cell carcinoma of the lung.
Takuya Ueda; Keiju Aokage; Hiroyoshi Nishikawa; Shinya Neri; Hiroshi Nakamura; Masato Sugano; Kenta Tane; Tomohiro Miyoshi; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Masahiko Kusumoto; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 144(5), 835-844, May 2018
Lead

Podoplanin-positive cancer-associated fibroblast recruitment within cancer stroma is associated with a higher number of single nucleotide variants in cancer cells in lung adenocarcinoma.
Shoko Nakasone; Sachiyo Mimaki; Tomohiro Ichikawa; Keiju Aokage; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Masahiro Tsuboi; Koichi Goto; Katsuya Tsuchihara; Genichiro Ishii
Journal of cancer research and clinical oncology, 144(5), 893-900, May 2018
Lead

A proposal for a comprehensive risk scoring system for predicting postoperative complications in octogenarian patients with medically operable lung cancer: JACS1303.
Hisashi Saji; Takahiko Ueno; Hiroshige Nakamura; Norihito Okumura; Masanori Tsuchida; Makoto Sonobe; Takuro Miyazaki; Keiju Aokage; Masayuki Nakao; Tomohiro Haruki; Hiroyuki Ito; Kazuhiko Kataoka; Kazunori Okabe; Kenji Tomizawa; Kentaro Yoshimoto; Hirotoshi Horio; Kenji Sugio; Yasuhisa Ode; Motoshi Takao; Morihito Okada; Masayuki Chida
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 53(4), 835-841, Apr. 2018
Lead

Influence of Ground Glass Opacity and the Corresponding Pathological Findings on Survival in Patients with Clinical Stage I Non-Small Cell Lung Cancer.
Keiju Aokage; Tomohiro Miyoshi; Genichiro Ishii; Masahiro Kusumoto; Shogo Nomura; Shinya Katsumata; Keigo Sekihara; Kenta Tane; Masahiro Tsuboi
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 13(4), 533-542, Apr. 2018
Lead

Long-term survival after complete resection of non-small-cell lung cancer in patients with interstitial lung disease.
Keigo Sekihara; Keiju Aokage; Tomonari Oki; Tomokazu Omori; Shinya Katsumata; Takuya Ueda; Tomohiro Miyoshi; Masaki Goto; Shoko Nakasone; Tomohiro Ichikawa; Tomoyuki Hishida; Junji Yoshida; Kakeru Hisakane; Koichi Goto; Masahiro Tsuboi
Interactive cardiovascular and thoracic surgery, 26(4), 638-643, Apr. 2018
Lead

The ratio of cancer cells to stroma within the invasive area is a histologic prognostic parameter of lung adenocarcinoma.
Tomohiro Ichikawa; Keiju Aokage; Masato Sugano; Tomohiro Miyoshi; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 118, 30-35, Apr. 2018
Lead

A randomized Phase III trial of lobe-specific vs. systematic nodal dissection for clinical Stage I-II non-small cell lung cancer (JCOG1413).
Tomoyuki Hishida; Hisashi Saji; Shun-Ichi Watanabe; Hisao Asamura; Keiju Aokage; Tomonori Mizutani; Masashi Wakabayashi; Taro Shibata; Morihito Okada
Japanese journal of clinical oncology, 48(2), 190-194, Feb. 2018
Lead

Abundant tumor promoting stromal cells in lung adenocarcinoma with hypoxic regions.
Hiroshi Nakamura; Tomohiro Ichikawa; Shoko Nakasone; Tomohiro Miyoshi; Masato Sugano; Motohiro Kojima; Satoshi Fujii; Atsushi Ochiai; Takeshi Kuwata; Keiju Aokage; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 115, 56-63, Jan. 2018
Lead

Neoadjuvant and adjuvant therapy for Stage III non-small cell lung cancer.
Shun-Ichi Watanabe; Kazuo Nakagawa; Kenji Suzuki; Kazuya Takamochi; Hiroyuki Ito; Jiro Okami; Keiju Aokage; Hisashi Saji; Hiroshige Yoshioka; Yoshitaka Zenke; Tadashi Aoki; Yasuhiro Tsutani; Morihito Okada
Japanese journal of clinical oncology, 47(12), 1112-1118, Dec. 2017
Lead

Effectiveness of Bone Suppression Imaging in the Detection of Lung Nodules on Chest Radiographs: Relevance to Anatomic Location and Observer's Experience.
Tomohiro Miyoshi; Junji Yoshida; Nao Aramaki; Yuki Matsumura; Keiju Aokage; Tomoyuki Hishida; Tsuyoshi Kobayashi; Shinichi Tsubura; Shinsuke Katsuhara; Satoshi Kasai; Yasuhiko Sasano; Kanji Nagai; Masahiro Tsuboi
Journal of thoracic imaging, 32(6), 398-405, Nov. 2017
Lead

Immunohistochemical and genetic characteristics of lung cancer mimicking organizing pneumonia.
Tomohiro Ichikawa; Koichi Saruwatari; Sachiyo Mimaki; Masato Sugano; Keiju Aokage; Motohiro Kojima; Tomoyuki Hishida; Satoshi Fujii; Junji Yoshida; Takeshi Kuwata; Atsushi Ochiai; Kenji Suzuki; Masahiro Tsuboi; Koichi Goto; Katsuya Tsuchihara; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 113, 134-139, Nov. 2017
Lead

Long-term survival outcome after postoperative recurrence of non-small-cell lung cancer: who is 'cured' from postoperative recurrence?
Keigo Sekihara; Tomoyuki Hishida; Junji Yoshida; Tomonari Oki; Tomokazu Omori; Shinya Katsumata; Takuya Ueda; Tomohiro Miyoshi; Masaki Goto; Syoko Nakasone; Tomohiro Ichikawa; Reiko Matsuzawa; Keiju Aokage; Koichi Goto; Masahiro Tsuboi
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 52(3), 522-528, Sep. 2017
Lead

Clinical and Pathological Staging Validation in the Eighth Edition of the TNM Classification for Lung Cancer: Correlation between Solid Size on Thin-Section Computed Tomography and Invasive Size in Pathological Findings in the New T Classification.
Keiju Aokage; Tomohiro Miyoshi; Genichiro Ishii; Masahiro Kusumoto; Shogo Nomura; Shinya Katsumata; Keigo Sekihara; Tomoyuki Hishida; Masahiro Tsuboi
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 12(9), 1403-1412, Sep. 2017
Lead

Thin-section computed tomography findings of lung adenocarcinoma with inherent metastatic potential.
Shigeki Suzuki; Keiju Aokage; Junji Yoshida; Genichiro Ishii; Yuki Matsumura; Tomohiro Haruki; Tomoyuki Hishida; Kanji Nagai
Surgery today, 47(5), 619-626, May 2017
Lead

A non-randomized confirmatory trial of segmentectomy for clinical T1N0 lung cancer with dominant ground glass opacity based on thin-section computed tomography (JCOG1211).
Keiju Aokage; Hisashi Saji; Kenji Suzuki; Tomonori Mizutani; Hiroshi Katayama; Taro Shibata; Syunichi Watanabe; Hisao Asamura
General thoracic and cardiovascular surgery, 65(5), 267-272, May 2017
Lead

Histology is a Prognostic Indicator After Pulmonary Metastasectomy from Renal Cell Carcinoma.
Yoichi Ohtaki; Kimihiro Shimizu; Keiju Aokage; Masayuki Nakao; Junji Yoshida; Mitsuhiro Kamiyoshihara; Masayuki Sugano; Yusuke Takahashi; Seshiru Nakazawa; Toshiteru Nagashima; Kai Obayashi; Tomoyuki Hishida; Masahiro Tsuboi; Shohei Mori; Mingyon Mun; Sakae Okumura; Hitoshi Igai; Noriyuki Matsutani; Akira Mogi; Hiroyuki Kuwano
World journal of surgery, 41(3), 771-779, Mar. 2017
Lead

Is cancer history really an exclusion criterion for clinical trial of lung cancer? Influence of gastrointestinal tract cancer history on the outcomes of lung cancer surgery.
Keiju Aokage; Morihito Okada; Kenji Suzuki; Shogo Nomura; Shigeki Suzuki; Norifumi Tsubokawa; Takahiro Mimae; Aritoshi Hattori; Tomoyuki Hishida; Junji Yoshida; Masahiro Tsuboi
Japanese journal of clinical oncology, 47(2), 145-156, Feb. 2017
Lead

Is cancer history really an exclusion criterion for clinical trial of lung cancer? Influence of gastrointestinal tract cancer history on the outcomes of lung cancer surgery.
Keiju Aokage; Morihito Okada; Kenji Suzuki; Shogo Nomura; Shigeki Suzuki; Norifumi Tsubokawa; Takahiro Mimae; Aritoshi Hattori; Tomoyuki Hishida; Junji Yoshida; Masahiro Tsuboi
Japanese journal of clinical oncology, 47(2), 190-190, Feb. 2017
Lead

Genomic Profiling of Large-Cell Neuroendocrine Carcinoma of the Lung.
Tomohiro Miyoshi; Shigeki Umemura; Yuki Matsumura; Sachiyo Mimaki; Satoshi Tada; Hideki Makinoshima; Genichiro Ishii; Hibiki Udagawa; Shingo Matsumoto; Kiyotaka Yoh; Seiji Niho; Hironobu Ohmatsu; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Kanji Nagai; Koichi Goto; Masahiro Tsuboi; Katsuya Tsuchihara
Clinical cancer research : an official journal of the American Association for Cancer Research, 23(3), 757-765, Feb. 2017
Lead

The ratio of cancer cells to stroma after induction therapy in the treatment of non-small cell lung cancer.
Masaki Goto; Masahito Naito; Koichi Saruwatari; Kakeru Hisakane; Motohiro Kojima; Satoshi Fujii; Takeshi Kuwata; Atsushi Ochiai; Shogo Nomura; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Kohei Yokoi; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 143(2), 215-223, Feb. 2017
Lead

Clinicopathological significance of caveolin-1 expression by cancer-associated fibroblasts in lung adenocarcinoma.
Kei Shimizu; Keisuke Kirita; Keiju Aokage; Motohiro Kojima; Tomoyuki Hishida; Takeshi Kuwata; Satoshi Fujii; Atsushi Ochiai; Kazuhito Funai; Junji Yoshida; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 143(2), 321-328, Feb. 2017
Lead

The role of pulmonary resection in tumors metastatic from esophageal carcinoma.
Jun Kanamori; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Masahiro Tsuboi; Takeo Fujita; Masato Nagino; Hiroyuki Daiko
Japanese journal of clinical oncology, 47(1), 25-31, Jan. 2017
Lead

Limited resection for early-stage non-small cell lung cancer as function-preserving radical surgery: a review.
Keiju Aokage; Junji Yoshida; Tomoyuki Hishida; Masahiro Tsuboi; Hisashi Saji; Morihito Okada; Kenji Suzuki; Syunichi Watanabe; Hisao Asamura
Japanese journal of clinical oncology, 47(1), 7-11, Jan. 2017
Lead

Wedge Resection Versus Anatomic Resection: Extent of Surgical Resection for Stage I and II Lung Cancer.
Hisao Asamura; Keiju Aokage; Masaya Yotsukura
American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 37, 426-433, 2017
Lead

Feasibility and efficacy of salvage lung resection after definitive chemoradiation therapy for Stage III non-small-cell lung cancer.
Yoshihisa Shimada; Kenji Suzuki; Morihito Okada; Haruhiko Nakayama; Hiroyuki Ito; Tetsuya Mitsudomi; Hisashi Saji; Kazuya Takamochi; Yujin Kudo; Aritoshi Hattori; Takahiro Mimae; Keiju Aokage; Teppei Nishii; Masahiro Tsuboi; Norihiko Ikeda
Interactive cardiovascular and thoracic surgery, 23(6), 895-901, Dec. 2016
Lead

Microenvironmental changes in the progression from adenocarcinoma in situ to minimally invasive adenocarcinoma and invasive lepidic predominant adenocarcinoma of the lung.
Masahito Naito; Keiju Aokage; Kouichi Saruwatari; Kakeru Hisakane; Tomohiro Miyoshi; Tomoyuki Hishida; Junji Yoshida; Sugano Masato; Motohiro Kojima; Takeshi Kuwata; Satoshi Fujii; Atsushi Ochiai; Yukitoshi Sato; Masahiro Tsuboi; Genichiro Ishii
Lung cancer (Amsterdam, Netherlands), 100, 53-62, Oct. 2016
Lead

Long-term outcome of surgical resection for residual or regrown advanced non-small cell lung carcinomas following EGFR-TKI treatment: report of four cases.
Tomoyuki Hishida; Junji Yoshida; Keiju Aokage; Kanji Nagai; Masahiro Tsuboi
General thoracic and cardiovascular surgery, 64(7), 429-33, Jul. 2016
Lead

The difference in Ezrin-pAkt signaling axis between lepidic and papillary predominant invasive adenocarcinomas of the lung.
Kazunori Hata; Junji Yoshida; Hibiki Udagawa; Hiroko Hashimoto; Satoshi Fujii; Tomoyuki Hishida; Takeshi Kuwata; Keiju Aokage; Motohiro Kojima; Atsushi Ochiai; Kenji Suzuki; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 142(7), 1421-30, Jul. 2016
Lead

Interstitial growth as an aggressive growth pattern in primary lung cancer.
Shigeki Suzuki; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Takeshi Kuwata; Chisako Yamauchi; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 142(7), 1591-8, Jul. 2016
Lead

Severity of lung fibrosis affects early surgical outcomes of lung cancer among patients with combined pulmonary fibrosis and emphysema.
Takahiro Mimae; Kenji Suzuki; Masahiro Tsuboi; Norihiko Ikeda; Kazuya Takamochi; Keiju Aokage; Yoshihisa Shimada; Yoshihiro Miyata; Morihito Okada
Medicine, 95(29), e4314, Jul. 2016
Lead

The association of intravascular stromal cells with prognosis in high-grade neuroendocrine carcinoma of the lung.
Keigo Sekihara; Tomoyuki Hishida; Shinnosuke Ikemura; Koichi Saruwatari; Masahiro Morise; Takeshi Kuwata; Satoshi Fujii; Motohiro Kojima; Atsushi Ochiai; Kazuhito Funai; Keiju Aokage; Junji Yoshida; Masahiro Tsuboi; Genichiro Ishii
Journal of cancer research and clinical oncology, 142(5), 905-12, May 2016
Lead

Postoperative oligo-recurrence of non-small-cell lung cancer: clinical features and survival†.
Tomoyuki Hishida; Junji Yoshida; Keiju Aokage; Kanji Nagai; Masahiro Tsuboi
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 49(3), 847-53, Mar. 2016
Lead

Drastic morphological and molecular differences between lymph node micrometastatic tumors and macrometastatic tumors of lung adenocarcinoma.
Nao Aramaki; Genichiro Ishii; Eiji Yamada; Masahiro Morise; Keiju Aokage; Motohiro Kojima; Tomoyuki Hishida; Junji Yoshida; Norihiko Ikeda; Masahiro Tsuboi; Atsushi Ochiai
Journal of cancer research and clinical oncology, 142(1), 37-46, Jan. 2016
Lead

Expression profiling of receptor tyrosine kinases in high-grade neuroendocrine carcinoma of the lung: a comparative analysis with adenocarcinoma and squamous cell carcinoma.
Yuki Matsumura; Shigeki Umemura; Genichiro Ishii; Koji Tsuta; Shingo Matsumoto; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Yuichiro Ohe; Hiroyuki Suzuki; Atsushi Ochiai; Koichi Goto; Kanji Nagai; Katsuya Tsuchihara
Journal of cancer research and clinical oncology, 141(12), 2159-70, Dec. 2015
Lead

Limited resection trial for pulmonary ground-glass opacity nodules: case selection based on high-resolution computed tomography-interim results.
Junji Yoshida; Genichiro Ishii; Tomoyuki Hishida; Keiju Aokage; Masahiro Tsuboi; Hiroyuki Ito; Tomoyuki Yokose; Haruhiko Nakayama; Kouzo Yamada; Kanji Nagai
Japanese journal of clinical oncology, 45(7), 677-81, Jul. 2015
Lead

Mediastinal nodal involvement in patients with clinical stage I non-small-cell lung cancer: possibility of rational lymph node dissection.
Tomohiro Haruki; Keiju Aokage; Tomohiro Miyoshi; Tomoyuki Hishida; Genichiro Ishii; Junji Yoshida; Masahiro Tsuboi; Hiroshige Nakamura; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 10(6), 930-6, Jun. 2015
Lead

Surgical outcomes of non-small-cell lung carcinoma in patients previously treated for gastric cancer.
Norifumi Tsubokawa; Takahiro Mimae; Keiju Aokage; Aritoshi Hattori; Kenji Suzuki; Kanji Nagai; Masahiro Tsuboi; Morihito Okada
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 47(4), 648-52, Apr. 2015
Lead

Ezrin-expressing lung adenocarcinoma cells and podoplanin-positive fibroblasts form a malignant microenvironment.
Shigeki Suzuki; Genichiro Ishii; Rie Matsuwaki; Shinya Neri; Hiroko Hashimoto; Chisako Yamauchi; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Mitsutomo Kohno; Kanji Nagai; Atsushi Ochiai
Journal of cancer research and clinical oncology, 141(3), 475-84, Mar. 2015
Lead

The availability of pre- and intraoperative evaluation of a solitary pulmonary nodule in breast cancer patients.
Tomonari Kinoshita; Junji Yoshida; Genichiro Ishii; Tomoyuki Hishida; Masahiro Wada; Keiju Aokage; Kanji Nagai
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 21(1), 31-6, 2015
Lead

Tumor-size-based morphological features of metastatic lymph node tumors from primary lung adenocarcinoma.
Eiji Yamada; Genichiro Ishii; Nao Aramaki; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Motohiro Kojima; Kanji Nagai; Atsushi Ochiai
Pathology international, 64(12), 591-600, Dec. 2014
Lead

Prognosis of lung cancer patients with a past history of colorectal cancer.
Aritoshi Hattori; Kenji Suzuki; Keiju Aokage; Takahiro Mimae; Kanji Nagai; Masahiro Tsuboi; Morihito Okada
Japanese journal of clinical oncology, 44(11), 1088-95, Nov. 2014
Lead

Prognostic impact of microscopic vessel invasion and visceral pleural invasion in non-small cell lung cancer: a retrospective analysis of 2657 patients.
Shinya Neri; Junji Yoshida; Genichiro Ishii; Yuki Matsumura; Keiju Aokage; Tomoyuki Hishida; Kanji Nagai
Annals of surgery, 260(2), 383-8, Aug. 2014
Lead

Immunophenotypic features of metastatic lymph node tumors to predict recurrence in N2 lung squamous cell carcinoma.
Rie Matsuwaki; Genichiro Ishii; Yoshitaka Zenke; Shinya Neri; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Satoshi Fujii; Haruhiko Kondo; Tomoyuki Goya; Kanji Nagai; Atsushi Ochiai
Cancer science, 105(7), 905-11, Jul. 2014
Lead

Impact of extratumoral lymphatic permeation on postoperative survival of non-small-cell lung cancer patients.
Yuki Matsumura; Tomoyuki Hishida; Yoshihisa Shimada; Genichiro Ishii; Keiju Aokage; Junji Yoshida; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 9(3), 337-44, Mar. 2014
Lead

Surgical outcomes after initial surgery for clinical single-station N2 non-small-cell lung cancer.
Tomoyuki Hishida; Junji Yoshida; Yuichiro Ohe; Keiju Aokage; Genichiro Ishii; Kanji Nagai
Japanese journal of clinical oncology, 44(1), 85-92, Jan. 2014
Lead

Multiple perivascular epithelioid cell tumors: clear cell tumor of the lung accompanied by angiomyolipoma of the liver.
Shinya Neri; Genichiro Ishii; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Mitsuyo Nishimura; Kanji Nagai
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 20 Suppl, 453-6, 2014
Lead

Identification of early t1b lung adenocarcinoma based on thin-section computed tomography findings.
Keiju Aokage; Junji Yoshida; Genichiro Ishii; Yuki Matsumura; Tomohiro Haruki; Tomoyuki Hishida; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 8(10), 1289-94, Oct. 2013
Lead

Low-fat diet management strategy for chylothorax after pulmonary resection and lymph node dissection for primary lung cancer.
Teruhisa Takuwa; Junji Yoshida; Shotaro Ono; Tomoyuki Hishida; Mitsuyo Nishimura; Keiju Aokage; Kanji Nagai
The Journal of thoracic and cardiovascular surgery, 146(3), 571-4, Sep. 2013
Lead

Identification of intravascular tumor microenvironment features predicting the recurrence of pathological stage I lung adenocarcinoma.
Kaoru Kaseda; Genichiro Ishii; Keiju Aokage; Akiko Takahashi; Takeshi Kuwata; Tomoyuki Hishida; Junji Yoshida; Mitsutomo Kohno; Kanji Nagai; Atsushi Ochiai
Cancer science, 104(9), 1262-9, Sep. 2013
Lead

The differences of biological behavior based on the clinicopathological data between resectable large-cell neuroendocrine carcinoma and small-cell lung carcinoma.
Tomonari Kinoshita; Junji Yoshida; Genichiro Ishii; Keiju Aokage; Tomoyuki Hishida; Kanji Nagai
Clinical lung cancer, 14(5), 535-40, Sep. 2013
Lead

Prognostic impact of intratumoural microvascular invasion and microlymphatic permeation on node-negative non-small-cell lung cancer: which indicator is the stronger prognostic factor?
Tomoyuki Hishida; Junji Yoshida; Ryo Maeda; Genichiro Ishii; Keiju Aokage; Mitsuyo Nishimura; Kanji Nagai
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 43(4), 772-7, Apr. 2013
Lead

Podoplanin-positive cancer-associated fibroblasts could have prognostic value independent of cancer cell phenotype in stage I lung squamous cell carcinoma: usefulness of combining analysis of both cancer cell phenotype and cancer-associated fibroblast phenotype.
Shotaro Ono; Genichiro Ishii; Kanji Nagai; Teruhisa Takuwa; Junji Yoshida; Mitsuyo Nishimura; Tomoyuki Hishida; Keiju Aokage; Satoshi Fujii; Norihiko Ikeda; Atsushi Ochiai
Chest, 143(4), 963-970, Apr. 2013
Lead

Forkhead box P3 regulatory T cells coexisting with cancer associated fibroblasts are correlated with a poor outcome in lung adenocarcinoma.
Tomonari Kinoshita; Genichiro Ishii; Nobuyoshi Hiraoka; Shunki Hirayama; Chisako Yamauchi; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Kanji Nagai; Atsushi Ochiai
Cancer science, 104(4), 409-15, Apr. 2013
Lead

The clinical outcome of non-small cell lung cancer patients with adjacent lobe invasion: the optimal classification according to the status of the interlobar pleura at the invasion point.
Yoichi Ohtaki; Tomoyuki Hishida; Junji Yoshida; Genichiro Ishii; Akikazu Kawase; Keiju Aokage; Mitsuyo Nishimura; Kanji Nagai
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 43(2), 302-9, Feb. 2013
Lead

Distinctive histopathological features of lepidic growth predominant node-negative adenocarcinomas 3-5 cm in size.
Yusuke Takahashi; Genichiro Ishii; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Kanji Nagai
Lung cancer (Amsterdam, Netherlands), 79(2), 118-24, Feb. 2013
Lead

Cancer-initiating cell marker-positive cells generate metastatic tumors that recapitulate the histology of the primary tumors.
Nobuhiko Nishijima; Genichiro Ishii; Kanji Nagai; Naho Atsumi; Keiju Aokage; Yuichi Tokunaga; Hideomi Ichinokawa; Yuichiro Ohe; Atsushi Ochiai
Pathology international, 63(2), 94-101, Feb. 2013
Lead

Prognostic impact of CD204-positive macrophages in lung squamous cell carcinoma: possible contribution of Cd204-positive macrophages to the tumor-promoting microenvironment.
Shunki Hirayama; Genichiro Ishii; Kanji Nagai; Shotaro Ono; Motohiro Kojima; Chisako Yamauchi; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Kenji Suzuki; Atsushi Ochiai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7(12), 1790-1797, Dec. 2012
Lead

Pulmonary metastasis from encapsulated cervical ectopic type a thymoma.
Tomonari Kinoshita; Junji Yoshida; Genichiro Ishii; Keiju Aokage; Tomoyuki Hishida; Kanji Nagai
The Annals of thoracic surgery, 94(6), e141-2, Dec. 2012
Lead

Reasonable extent of lymph node dissection in intentional segmentectomy for small-sized peripheral non-small-cell lung cancer: from the clinicopathological findings of patients who underwent lobectomy with systematic lymph node dissection.
Yuki Matsumura; Tomoyuki Hishida; Junji Yoshida; Keiju Aokage; Genichiro Ishii; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7(11), 1691-7, Nov. 2012
Lead

The recurrence of malignant pleural mesothelioma 14 years after extrapleural pneumonectomy: possible histological transformation.
Tomonari Kinoshita; Genichiro Ishii; Yuki Matsumura; Toshihiro Shiozawa; Keiju Aokage; Tomoyuki Hishida; Junji Yoshida; Kanji Nagai
Pathology international, 62(11), 754-7, Nov. 2012
Lead

Long-term outcomes of 50 cases of limited-resection trial for pulmonary ground-glass opacity nodules.
Masayuki Nakao; Junji Yoshida; Koichi Goto; Genichiro Ishii; Akikazu Kawase; Keiju Aokage; Tomoyuki Hishida; Mitsuyo Nishimura; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 7(10), 1563-6, Oct. 2012
Lead

Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis.
Yuki Matsumura; Genichiro Ishii; Keiju Aokage; Takeshi Kuwata; Tomoyuki Hishida; Junji Yoshida; Mitsuyo Nishimura; Kanji Nagai; Atsushi Ochiai
Cancer science, 103(7), 1342-7, Jul. 2012
Lead

Differences between squamous cell carcinoma and adenocarcinoma of the lung: are adenocarcinoma and squamous cell carcinoma prognostically equal?
Akikazu Kawase; Junji Yoshida; Genichiro Ishii; Masayuki Nakao; Keiju Aokage; Tomoyuki Hishida; Mitsuyo Nishimura; Kanji Nagai
Japanese journal of clinical oncology, 42(3), 189-95, Mar. 2012
Lead

Molecular oncology of lung cancer.
Shinichi Toyooka; Tetsuya Mitsudomi; Junichi Soh; Keiju Aokage; Masaomi Yamane; Takahiro Oto; Katsuyuki Kiura; Shinichiro Miyoshi
General thoracic and cardiovascular surgery, 59(8), 527-37, Aug. 2011
Lead

Dynamic molecular changes associated with epithelial-mesenchymal transition and subsequent mesenchymal-epithelial transition in the early phase of metastatic tumor formation.
Keiju Aokage; Genichiro Ishii; Yoichi Ohtaki; Yoko Yamaguchi; Tomoyuki Hishida; Junji Yoshida; Mitsuyo Nishimura; Kanji Nagai; Atsushi Ochiai
International journal of cancer, 128(7), 1585-95, Apr. 2011
Lead

Prognostic significance of a solid component in pulmonary adenocarcinoma.
Yoichi Ohtaki; Junji Yoshida; Genichiro Ishii; Keiju Aokage; Tomoyuki Hishida; Mitsuyo Nishimura; Izumi Takeyoshi; Kanji Nagai
The Annals of thoracic surgery, 91(4), 1051-7, Apr. 2011
Lead

Histological progression of small intrapulmonary metastatic tumor from primary lung adenocarcinoma.
Keiju Aokage; Genichiro Ishii; Junji Yoshida; Tomoyuki Hishida; Mitsuyo Nishimura; Kanji Nagai; Atsushi Ochiai
Pathology international, 60(12), 765-73, Dec. 2010
Lead

Subcarinal lymph node in upper lobe non-small cell lung cancer patients: is selective lymph node dissection valid?
Keiju Aokage; Junji Yoshida; Genichiro Ishii; Tomoyuki Hishida; Mitsuyo Nishimura; Kanji Nagai
Lung cancer (Amsterdam, Netherlands), 70(2), 163-7, Nov. 2010
Lead

Prognostic impact of node involvement pattern in pN1 non-small cell lung cancer patients.
Masayuki Nakao; Junji Yoshida; Genichiro Ishii; Akikazu Kawase; Ryo Maeda; Keiju Aokage; Tomoyuki Hishida; Mitsuyo Nishimura; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 5(10), 1576-82, Oct. 2010
Lead

Histopathologic features of the tumor budding in adenocarcinoma of the lung: tumor budding as an index to predict the potential aggressiveness.
Yoko Yamaguchi; Genichiro Ishii; Motohiro Kojima; Kiyotaka Yoh; Hajime Otsuka; Yoichi Otaki; Keiju Aokage; Shingo Yanagi; Kanji Nagai; Yutaka Nishiwaki; Atsushi Ochiai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 5(9), 1361-8, Sep. 2010
Lead

Long-term survival and risk factors for recurrence in stage I non-small cell lung cancer patients with tumors up to 3 cm in maximum dimension.
Ryo Maeda; Junji Yoshida; Genichiro Ishii; Tomoyuki Hishida; Keiju Aokage; Mitsuyo Nishimura; Yutaka Nishiwaki; Kanji Nagai
Chest, 138(2), 357-62, Aug. 2010
Lead

Long-term outcome and late recurrence in patients with completely resected stage IA non-small cell lung cancer.
Ryo Maeda; Junji Yoshida; Genichiro Ishii; Keiju Aokage; Tomoyuki Hishida; Mitsuyo Nishimura; Yutaka Nishiwaki; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 5(8), 1246-50, Aug. 2010
Lead

Late recurrence of non-small cell lung cancer more than 5 years after complete resection: incidence and clinical implications in patient follow-up.
Ryo Maeda; Junji Yoshida; Tomoyuki Hishida; Keiju Aokage; Mitsuyo Nishimura; Yutaka Nishiwaki; Kanji Nagai
Chest, 138(1), 145-50, Jul. 2010
Lead

Impact of positive pleural lavage cytology on survival in patients having lung resection for non-small-cell lung cancer: An international individual patient data meta-analysis.
Eric Lim; Rachel Clough; Peter Goldstraw; Lyn Edmonds; Keiju Aokage; Junji Yoshida; Kanji Nagai; Yasushi Shintani; Mitsunori Ohta; Meinoshin Okumura; Teruo Iwasaki; Tsutomu Yasumitsu; Morihito Okada; Takeshi Mimura; Noriaki Tsubota; Tatsuo Nakagawa; Norihito Okumura; Yukitoshi Satoh; Sakae Okumura; Ken Nakagawa; Masahiko Higashiyama; Ken Kodama; Marc Riquet; Giovanni Vicidomini; Mario Santini; Christophoros Kotoulas; Jeng-Yuan Hsu; Chih-Yi Chen
The Journal of thoracic and cardiovascular surgery, 139(6), 1441-6, Jun. 2010
Lead

The impact on survival of positive intraoperative pleural lavage cytology in patients with non-small-cell lung cancer.
Keiju Aokage; Junji Yoshida; Genichiro Ishii; Sotarou Enatsu; Tomoyuki Hishida; Mitsuyo Nishimura; Yutaka Nishiwaki; Kanji Nagai
The Journal of thoracic and cardiovascular surgery, 139(5), 1246-52, May 2010
Lead

Possible delayed cut-end recurrence after limited resection for ground-glass opacity adenocarcinoma, intraoperatively diagnosed as Noguchi type B, in three patients.
Junji Yoshida; Genichiro Ishii; Tomoyuki Yokose; Keiju Aokage; Tomoyuki Hishida; Mitsuyo Nishimura; Takuya Onuki; Masayuki Noguchi; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 5(4), 546-50, Apr. 2010
Lead

Breast cancer with cartilaginous and/or osseous metaplasia diagnosed by lymph nodal metastasis: a case report.
Kazunori Tsukuda; Hisashi Tsuji; Tadayoshi Kunitomo; Keiju Aokage; Takayoshi Miyake; Saki Nakahara; Hiroko Masuda
Acta medica Okayama, 63(6), 367-71, Dec. 2009
Lead

Living-donor lobar lung transplantation and closure of atrial septal defect for adult Eisenmenger's syndrome.
Keiju Aokage; Hiroshi Date; Megumi Okazaki; Yoshifumi Sano; Takahiro Oto; Kengo Kusano; Keiji Goto; Shunji Sano; Shinichiro Miyoshi
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 28(10), 1107-9, Oct. 2009
Lead

Predominant infiltration of macrophages and CD8(+) T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer.
Osamu Kawai; Genichiro Ishii; Kaoru Kubota; Yukinori Murata; Yoichi Naito; Tetsuya Mizuno; Keiju Aokage; Nagahiro Saijo; Yutaka Nishiwaki; Akihiko Gemma; Syoji Kudoh; Atsushi Ochiai
Cancer, 113(6), 1387-95, Sep. 2008
Lead

Long-term survival in two cases of resected gastric metastasis of pulmonary pleomorphic carcinoma.
Keiju Aokage; Junji Yoshida; Genichiro Ishii; Shinichiro Takahashi; Masanori Sugito; Mitsuyo Nishimura; Atsushi Ochiai; Kanji Nagai
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 3(7), 796-9, Jul. 2008
Lead

Annual abdominal ultrasonographic examination after curative NSCLC resection.
Keiju Aokage; Junji Yoshida; Mitsuyo Nishimura; Yutaka Nishiwaki; Kanji Nagai
Lung cancer (Amsterdam, Netherlands), 57(3), 334-8, Sep. 2007
Lead

Intrapulmonary metastasis in resected pathologic stage IIIB non-small cell lung cancer: possible contribution of aerogenous metastasis to the favorable outcome.
Keiju Aokage; Genichiro Ishii; Kanji Nagai; Osamu Kawai; Yoichi Naito; Takahiro Hasebe; Mitsuyo Nishimura; Junji Yoshida; Atsushi Ochiai
The Journal of thoracic and cardiovascular surgery, 134(2), 386-91, Aug. 2007
Lead

Post-mortem administration of urokinase in canine lung transplantation from non-heart-beating donors.
Ryujiro Sugimoto; Hiroshi Date; Seiichiro Sugimoto; Mikio Okazaki; Keiju Aokage; Hidetoshi Inokawa; Motoi Aoe; Yoshifumi Sano
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 25(9), 1148-53, Sep. 2006
Lead

Optimal time for post-mortem heparinization in canine lung transplantation with non-heart-beating donors.
Mikio Okazaki; Hiroshi Date; Hidetoshi Inokawa; Daisuke Okutani; Keiju Aokage; Itaru Nagahiro; Motoi Aoe; Yoshifumi Sano; Nobuyoshi Shimizu
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 25(4), 454-60, Apr. 2006
Lead

A canine experimental study to assess the potential of unilateral double lobar lung transplantation.
Keiju Aokage; Hiroshi Date; Ryujiro Sugimoto; Mikio Okazaki; Daisuke Okutani; Hidetoshi Inokawa; Motoi Aoe; Nobuyoshi Shimizu
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 29(1), 40-4, Jan. 2006
Lead

Effects of postmortem heparinization in canine lung transplantation with non-heart-beating donors.
Hidetoshi Inokawa; Hiroshi Date; Mikio Okazaki; Daisuke Okutani; Keiju Aokage; Itaru Nagahiro; Motoi Aoe; Yoshifumi Sano; Nobuyoshi Shimizu
The Journal of thoracic and cardiovascular surgery, 129(2), 429-34, Feb. 2005
Lead

肺尖部胸壁浸潤癌に対する化学放射線療法後の術前後デュルバルマブもしくはデュルバルマブ維持療法を併用した集学的治療に関する単群検証的試験（JCOG1807C）
臨床研究・治験推進研究事業, 国立研究開発法人日本医療研究開発機構
国立研究開発法人国立がん研究センター
2024 - 2027

胸部薄切CT所見に基づく早期肺癌に対する経過観察の単群検証的試験
日本医療研究開発機構研究費 革新的がん医療実用化研究事業, 国立研究開発法人日本医療研究開発機構
国立研究開発法人国立がん研究センター
2024 - 2026

臨床病期I/II期非小細胞肺癌におけるリンパ節郭清の縮小化の治療的意義を検証するランダム化比較試験
日本医療研究開発機構研究費 革新的がん医療実用化研究事業, 国立研究開発法人日本医療研究開発機構
広島大学
2023 - 2025

特発性肺線維症（IPF）合併臨床病期I期非小細胞肺癌に対する肺縮小手術に関するランダム化比較第III相試験
日本医療研究開発機構研究費 革新的がん医療実用化研究事業, 国立研究開発法人日本医療研究開発機構
広島大学
2023 - 2025

非浸潤または小型非小細胞肺がんに対する機能温存手術の確立に関する研究
日本医療研究開発機構研究費 革新的がん医療実用化研究事業, 国立研究開発法人日本医療研究開発機構
国立研究開発法人国立がん研究センター
2023 - 2024

がん全ゲノム解析等による実践的個別化医療体系構築と拡充をめざした多施設共同研究
革新的がん医療実用化研究事業, 国立研究開発法人日本医療研究開発機構
国立研究開発法人国立がん研究センター
2022 - 2026

Analysis of PD-1+ tumor-infiltrating T cells according to cancer antigen hierarchy
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
01 Apr. 2020 - 31 Mar. 2023

Quantitative diagnosis of early-stage lung cancer by fusing non-contrast and contrast high-definition CT images
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
The University of Tokushima
01 Apr. 2020 - 31 Mar. 2023

Association of immune responses with racial differences of cancer development
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (S)
Nagoya University
31 May 2017 - 31 Mar. 2022

Immunological assay for development of a novel treatment guideline in malignant melanoma
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Exploratory Research
Nagoya University
01 Apr. 2016 - 31 Mar. 2018

Cancer Diagnosis and Prognosis Assistance Based on Multidisciplinary Computational Anatomy
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
The University of Tokushima
10 Jul. 2014 - 31 Mar. 2019

Lung cancer probability and prognostic prediction using a large-scale CT image database
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
The University of Tokushima
01 Apr. 2014 - 31 Mar. 2017

Activation of anti-tumor immune responses by the control of regulatory T cells
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Scientific Research (B)
01 Apr. 2014 - 31 Mar. 2017

Genomic profiling of large-cell neuroendocrine cartinoma of the lung for the development of new targeted therapies
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Young Scientists (B)
National Cancer Center Japan
01 Apr. 2014 - 31 Mar. 2016

Development of target therapy for stromal cells
Grants-in-Aid for Scientific Research, Japan Society for the Promotion of Science, Grant-in-Aid for Challenging Exploratory Research
National Center of Neurology and Psychiatry
01 Apr. 2012 - 31 Mar. 2014