医学博士, 新潟大学（日本）

Anatomy and histopathology of nervous system, Neurodegenerative desease

Anterior horn damage in brachial multisegmental amyotrophy with superficial siderosis and dural tear: an autopsy case report.
151. Takahashi Y, Kodaira1 M, Yamada M, Uehara K, Ito K, Kaneko T, Ohashi H, Yazaki M, Sekijima Y.
BMC Neurol., 23, 129, 2023, Refereed

The large neuron involvement in the neostriatum in Lewy body diseases.
Oyanagi K, Hayashi H, Yamada M, Kakita A.
Neuropathology, 42, 459-463, 2022

Delayed detection of hydrocephalus following mildly traumatic subarachnoid hemorrhage in corticobasal degeneration: A case report.
Mochizuki Y, Kodaira M, Kondo Y, Yamada M, Kuroiwa M, Kaneko T, Sato M, Sekijima Y.
Case Rep Neurol, 14, 268-273, 2022

Praja1 RING-finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease-associated protein aggregation.
Watabe K, Niida-Kawaguchi M, Tada M, Kato Y, Murata M, Tanji K, Wakabayashi K, Yamada M, Kakita A, Shibata N.
Neuropathology, 2022

The neostriatum in polyglutamine diseases: preferential decreases in large neurons in dentatorubral-pallidoluysian atrophy and Machado-Joseph disease, but in small neurons in Huntington disease.
Oyanagi K, Shimizu H, Yamada M, Kakita A.
Neuropathology, 2022

Repeat conformation heterogeneity in cerebellar ataxia, neuropathy, vestibular areflexia syndrome.
Miyatake S, Yoshida K, Yamada M, Doi H, Tsuyuzaki J, Kodaira M, Koshimizu E, Taguri M, Imamura S, Fukuda H, Hamanaka K, Fujita A, Satoh M, Miyama T, Watanabe N, Onoue H, Koyano S, Kurita Y, Takahashi T, Ueda N, Tanaka K, Miyake N, Tanaka F, Mizuguchi T and Matsumoto N.
Brain, 145(3), 1139-1150, 2021, Refereed

Pathologic basis of the preferential thinning of the corpus callosum in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP).
Kinoshita M, Oyanagi K, Kondo Y, Ishizawa K, Ishihara K, Yoshida M, Inoue T, Mitsuyama Y, Yoshida K, Yamada M, Sekijima Y, Ikeda S
eNeurologicalSci, 22, 2021, Refereed

An elderly case of paraneoplastic anti-NMDA receptor encephalitis associated with small-cell lung cancer expressing NR1 subunits.
Kobayashi Y, Sato M, Kinoshita M, Kakizawa M, Higuchi K, Yamada M, Kodaira M, Sekijima Y
Intern Med, 59, 2307–2309, 2020, Refereed

Appropriate surgical procedures for Chiari type 1 malformation and associated syrinx based on radiological characteristics of the craniovertebral junction.
Ito K, Yamada M, Horiuchi T, Hongo K.
Neurosurg Rev, 2019

A Japanese Family of Spinocerebellar Ataxia Type 21: Clinical and Neuropathological Studies.
Yahikozawa H, Miyatake S, Sakai T, Uehara T, Yamada M, Hanyu N, Futatsugi Y, Doi H, Koyano S, Tanaka F, Suzuki A, Matsumoto N, Yoshida K.
CEREBELLUM, 17(5), 525-530, 2018

Brain gangliosides in Alzheimer’s disease: Increased expression of cholinergic neuron-specific gangliosides.
Fukami Y, Ariga T, Yamada M, Yuki N.
Curr Alzheimer Res, 14, 1-6, 2017, Refereed

Complete remission of isolated central nervous system lymphomatoid granulomatosis associated with acquired immunodeficiency syndrome: a case report and literature review.
Kano, Y, Kodaira M, Ushiki A, Kosaka M, Yamada M, Shingu K, Nishihara H, Hanaoka M, Sekijima Y.
Intern Med, 56, 2497-2501, 2017

脊髄小脳変性症における神経病理の変遷： ポリグルタミン病を巡る20年
山田光則
信州医学雑誌, 65(5), 249-257, 2017

Spinocerebellar degeneration: Discrepancies between clinical and pathological diagnoses.
Yamada M, Toyoshima Y, Makifuchi T, Kakita A, Takahashi H.
2016

Clinicopathological features in anterior visual pathway in neuromyelitis optica.
Hokari M, Yokoseki A, Arakawa M, Saji E, Yanagawa K, Yanagimura F, Toyoshima Y, Okamoto K, Ueki S, Hatase T, Ohashi R, Fukuchi T, Akazawa K, Yamada M, Kakita A, Takahashi H, Nishizawa M, Kawachi I.
2016

The type III transporters (PiT-1 and PiT-2) are the major sodium-dependent phosphate transporters in the mice and human brains.
Inden M, Iriyama M, Zennami M, Sekine S, Hara A, Yamada M, Hozumi I.
2016

Cerebral amyloid angiopathy in post-transplant patients with hereditary ATTR amyloidosis.
Sekijima Y, Yazaki M, Oguchi K, Ezawa N, Yoshinaga T, Yamada M, Yahikozawa H, Watanabe M, Kametani F, Ikeda S.
2016

A Fulminant Case of Granulomatosis with Polyangiitis with Meningeal and Parenchymal Involvement.
Yajima R, Toyoshima Y, Wada Y, Takahashi T, Arakawa H, Ito G, Kobayashi D, Yamada M, Kawachi I, Narita I, Takahashi H, Nishizawa M.
Case Rep Neurol., 2015

Variants associated with Gaucher disease in multiple system atrophy.
Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Takashima H, Kikuchi A, Aoki M, Ishiura H, Yasuda T, Date H, Ahsan B, Iwata A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S.
2015

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, Kambe T, Yamada M, Inden M, Hara H, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I.
J Neurosci Res, 93, 370-379, 2015, Refereed

Generation of Rat Induced Pluripotent Stem Cells using a non-viral vector and variation in reactivity to a cell surface keratan sulfate recognizing antibody.
Makanga JO, Kobayashi M, Ikeda H, Christianto A, Yamada M, Kawasaki T, Inazu T.
Biol Pharm Bullet, 38, 127-133, 2015, Refereed

ポリグルタミン病における異常蛋白伝播
山田光則
Clinical Neuroscience, 33(3), 332-334, 2015

Neostriatum in patients with polyglutamine diseases: a quantitative and immunohistological investigation
Oyanagi K, Shimizu H, Yamada M, Kakita A
2020, 日本神経病理学会

高齢で発症し自然経過を辿った多系統萎縮症の一剖検例．
福島和広，宮平鷹揚，小口賢哉，中村昭則，武井洋一，大原愼司，腰原啓史，山田光則．
2019, 日本神経病理学会上信越地方会

中枢神経病変を有する成人ランゲルハンス細胞組織球症の１剖検例．
山田光則，小出隆司，藤尾由美，屋代英樹，内藤加奈子，田川朝子，川島裕平，木花いづみ，亀山香織，上野彰久，松本有機．
2019, 日本神経病理学会

BPAN/SENDA: impairment of autophagy and its clinicopathological implications.
Shimizu H, Muramatsu K, Morishita H, Seike N, Tanaka H, Shimizu N, Sawamura M, Ozawa T, Shimomura T, Yamada M, Mizushima N, Kakita A.
2019, 日本神経病理学会

振戦で発症後パーキンソニズムと垂直性眼球運動障害を呈したFTLD-TDP：3剖検例の臨床病理像．
田中英智，豊島靖子，清水宏，他田真理，石原智彦，坂井健二，岩永圭介，川崎浩一，若林孝一，山田光則，高橋均，小野寺理，柿田明美．
2019, 日本神経病理学会

異常蛋白はシナプスを越えるのか。ポリグルタミン
山田光則
第55回日本神経病理学会総会, 2014

神経病理学のゆくえ
山田光則
第6回日本神経病理学会東海・北陸地方会, 2014, Invited

日本神経病理学会

日本病理学会

日本神経学会

日本小児神経学会